CN105213061A - A kind of medical experiment animal fixing device - Google Patents

A kind of medical experiment animal fixing device Download PDF

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Publication number
CN105213061A
CN105213061A CN201510512181.0A CN201510512181A CN105213061A CN 105213061 A CN105213061 A CN 105213061A CN 201510512181 A CN201510512181 A CN 201510512181A CN 105213061 A CN105213061 A CN 105213061A
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CN
China
Prior art keywords
animal
box
fixing device
medical experiment
sidewall
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201510512181.0A
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Chinese (zh)
Inventor
王磊
张利
吕维加
潘浩波
彭松林
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Shenzhen Institute of Advanced Technology of CAS
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Shenzhen Institute of Advanced Technology of CAS
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Publication date
Application filed by Shenzhen Institute of Advanced Technology of CAS filed Critical Shenzhen Institute of Advanced Technology of CAS
Priority to CN201510512181.0A priority Critical patent/CN105213061A/en
Publication of CN105213061A publication Critical patent/CN105213061A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61DVETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D3/00Appliances for supporting or fettering animals for operative purposes

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Husbandry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Catching Or Destruction (AREA)

Abstract

The invention provides a kind of medical experiment animal fixing device, comprise and detect box and fixed part, the sidewall that described detection box to comprise at the bottom of box and upwards extends along box feather edge, at the bottom of described box and described sidewall jointly surround one for accommodating the receiving space of animal, be provided with the detection zone that at least one light conducting stimulates or pain stimulates at the bottom of described box, described fixed part is arranged at the box basal surface of described detection box or sidewall surfaces for the limbs to be detected of animal are fixed on described detection zone.Medical experiment animal fixing device provided by the invention can make laboratory animal limbs to be detected rest in surveyed area and retain certain limb range of activity in the wrong, move after avoiding animal to be subject to pain stimulation or change position, keep Therapy lasted to carry out, make experimental implementation time saving and energy saving; Simultaneously apparatus of the present invention simple and easy, easily assemble, simple to operate.

Description

A kind of medical experiment animal fixing device
Technical field
The present invention relates to medical experiment animal device field, be specifically related to a kind of medical experiment animal fixing device.
Background technology
Burning pain stimulation instrument is a kind of Special experimental instrument for pain sensation research, but because it is unified, can the supporting animal experiment device capable of convenient assembling, therefore, research worker need make animal experiment device capable by oneself when using this instrument, homemade device is general more complicated, and the homemade time is longer.In addition, homemade animal experiment device capable often cannot allow laboratory animal limbs to be detected rest in particular detection region, animal is after being subject to pain stimulation, position or movement can be changed, force experiment to be interrupted, cause detecting the insincere or distortion of data, the persistence of testing can not be kept, finally cause experimental implementation to waste time and energy, have impact on the progress of experiment and the service efficiency of instrument.
Summary of the invention
For solving the problem, the invention provides a kind of medical experiment animal fixing device.This device is simple and practical, and laboratory animal limbs to be detected can be made to be fixed in particular detection region, and avoid mobile or change position, what maintenance was tested continues to carry out.Described device can support the use with burning pain stimulation instrument simultaneously.
The invention provides a kind of medical experiment animal fixing device, comprise and detect box and fixed part, the sidewall that described detection box to comprise at the bottom of box and upwards extends along box feather edge, at the bottom of described box and described sidewall jointly surround one for accommodating the receiving space of animal, be provided with the detection zone that at least one light conducting stimulates or pain stimulates at the bottom of described box, described fixed part is arranged at the box basal surface of described detection box or sidewall surfaces for being fixed in described detection zone by the limbs to be detected of animal.
Preferably, animal fixing device of the present invention uses for coordinating the instrument providing described photostimulation or described pain to stimulate.
Preferably, the material of described detection zone is float glass.
Preferably, described fixed part comprises the fixture of fixing band for bondage animal and fixing described fixing band.
More preferably, described fixed part comprises at least two fixtures and a fixing band, described fixture is oppositely arranged on the sidewall of described detection box respectively, the two ends of described fixing band are individually fixed on described fixture, described fixing band is provided with magic tape, a receiving space is formed, for binding the abdominal part of animal and making the limbs to be detected of animal be positioned at described detection zone after described magic tape bonding.
More preferably, described fixture is projecting fence on described sidewall, screw or the projection being provided with through hole.
More preferably, described fixing band is fixed on described fixture by hook, safety buckle or direct mode of binding.
Further preferably, described fence comprises two montants erect and the many cross bars be vertically fixed between two described montants, and described cross bar is arranged between described two montants equidistantly.
Further preferably, the two ends of described fixing band are directly bound to respectively on the cross bar on two described fence, by the described cross bar that described fixing band is bundled in differing heights adjusting the level altitude of animal.
Preferably, described medical experiment animal fixing device comprises the support component for supporting described detection box.
Medical experiment animal fixing device provided by the invention can make laboratory animal limbs to be detected rest in surveyed area and retain certain limb range of activity in the wrong, move after avoiding animal to be subject to pain stimulation or change position, Therapy lasted is kept to carry out, make experimental implementation time saving and energy saving, simple; Apparatus of the present invention are simple and easy, simple to operate simultaneously, can support the use with burning pain stimulation instrument.
To sum up, beneficial effect of the present invention comprises the following aspects:
1, animal fixing device provided by the invention can make laboratory animal limbs to be detected rest in particular detection region, moves or change position after avoiding animal to be subject to pain stimulation, keeps Therapy lasted to carry out;
2, apparatus of the present invention are simple and easy, simple to operate, can support the use with burning pain stimulation instrument.
Accompanying drawing explanation
Fig. 1 is the structural representation of an embodiment of the present invention Chinese medicine experimental animal fixing device;
Fig. 2 is the detection box of an embodiment of the present invention Chinese medicine experimental animal fixing device and the structural representation of fixed part;
Fig. 3 is the structural representation that an embodiment of the present invention comprises the medical experiment animal fixing device of support component;
Fig. 4 is the structural representation of support component in an embodiment of the present invention;
Fig. 5 is the structural representation of support column in an embodiment of the present invention.
Detailed description of the invention
The following stated is the preferred embodiment of the present invention; it should be pointed out that for those skilled in the art, under the premise without departing from the principles of the invention; can also make some improvements and modifications, these improvements and modifications are also considered as protection scope of the present invention.
The invention provides a kind of medical experiment animal fixing device, comprise and detect box and fixed part, detect the sidewall that box to comprise at the bottom of box and upwards extends along box feather edge, at the bottom of box and sidewall jointly surround one for accommodating the receiving space of animal, be provided with the detection zone that at least one light conducting stimulates or pain stimulates at the bottom of box, fixed part is arranged at and detects the box basal surface of box or sidewall surfaces for the limbs to be detected of animal are fixed on detection zone.
Preferably, animal fixing device of the present invention is for coordinating the use of the instrument providing photostimulation or pain to stimulate.
More preferably, animal fixing device of the present invention is for coordinating the use of the full-automatic burning pain stimulation instrument of BME-410C type.
Laboratory animal device provided by the invention in like manner with the burning pain stimulation instrument of other models, the instrument similar with burning pain stimulation instrument or can support the use with the instrument of other types.
Preferably, detect box and be provided with opening, be convenient to animal to be placed in this receiving space.
Preferably, four sidewalls that box to comprise at the bottom of box and upwards extends along box feather edge are detected.
More preferably, the wide * height of long * detecting box is 30cm*20cm*20cm.
Preferably, the material detecting box sidewall is plank, metal or glass.
Preferably, the material at the bottom of box is glass.
Preferably, the material of the detection zone at the bottom of box is float glass, and except detection zone, at the bottom of box, other zone material are not limit.
Except detection zone material is float glass, other zone material at the bottom of box are not limit, can be plank or metal, when at the bottom of material and the box of detection zone, the material in other regions is different, the float glass of detection zone with other regions at the bottom of box as plank or metal can be connected by modes such as bonding, inlay.
Preferably, detection zone is diameter is 5cm, thickness is the border circular areas of 3mm.
Preferably, the position of detection zone is positioned at the central area detected at the bottom of box box.
Preferably, detection zone is two, is symmetricly set on the two ends detected at the bottom of box box respectively, for forelimb and the hind leg of difference test animal.
Preferably, fixed part comprises the fixture of fixing band for bondage animal and fixing fixing band.
More preferably, fixed part comprises a fixture and a fixing band, and fixture is arranged on sidewall, and fixing band one end is fixed on sidewall, and the other end is used for bondage animal.
More preferably, fixed part comprises at least two fixtures and a fixing band, fixture is oppositely arranged on the sidewall of detection box respectively, the two ends of fixing band are individually fixed on fixture, fixing band is provided with magic tape, a receiving space is formed, for binding the abdominal part of animal and making the limbs to be detected of animal be fixed in detection zone after magic tape bonding.
More preferably, fixture is projecting fence on sidewall, screw or the projection being provided with through hole.
More preferably, fixing band is fixed on fixture by hook, safety buckle or direct mode of binding.
Further preferably, the end of fixing band is provided with hook, and fixture is the projecting projection at sidewall, and projection has the through hole being suitable for linking up with mounting.
Further preferably, fence comprises two montants erect and the many cross bars be fixed on perpendicular to montant between two montants, and cross bar is arranged between two montants equidistantly.
Further preferably, the montant in fence is perpendicular to box baseplane.
Further preferably, the two ends of fixing band are directly bound to respectively on the cross bar on two fence, by the cross bar that fixing band is bundled in differing heights adjusting the level altitude of animal.By fixing band being fixed on cross bars different on fence with the level altitude of the height and then adjustment animal that adjust fixing band.The height of animal of the present invention is that animal foot can land, and can lift lower limb, but can not be unsettled.
Preferably, fence is fixed on by welding, bonding or other fixed forms and detects on box sidewall.
Preferably, fence is arranged on the centre position of sidewall or is symmetricly set on the two ends of sidewall.
Preferably, the number of fence is 2 or 4, can arrange according to the fixing tightness of the size of animal or needs.
Preferably, the distance between two montants of fence is 1cm.
Preferably, fixing band is the flat elastic ribbon being provided with magic tape.
More preferably, flat elastic ribbon is rubber strip or belt, and width is 1cm.
Preferably, the length of fixing band is 28cm.
Preferably, magic tape is sewn on binding strip.
Preferably, the width of magic tape is 1cm.
Preferably, medical experiment animal fixing device comprises for supporting the support component detecting box.
Support component concrete structure is not limit, and can support and detects box and have the space of placing the instrument providing photostimulation or pain to stimulate.
Preferably, support component comprises cushion block and expansion link or support column, detects box and is connected by cushion block with expansion link or support column.
Preferably, support component comprises four pieces of cushion blocks and four support columns, and cushion block is arranged on four angles place at the bottom of box, detects box and is connected by cushion block with support column.
Preferably, cushion block with at the bottom of box by welding, bonding or other modes are fixedly connected with.
Preferably, the material of cushion block is metal.
Preferably, the height of cushion block is 2cm.
Preferably, cushion block offers screwed hole, support column is threaded with cushion block.
Preferably, the height of support column is 34cm.
Preferably, support column comprises the first support column and the second support column, and the first support column is threaded with cushion block, and the second support column is threaded with the first support column.
Preferably, the height of the first support column is 18cm, and the height of the second support column is 16cm.
More preferably, the external thread length of the first support column is 1.5cm, and the external thread length of the second support column is 1.5cm.
Support column of the present invention is detachable, thus can reduce the volume of this animal fixing device.
Fig. 1 is the structural representation of an embodiment of the present invention Chinese medicine experimental animal fixing device, and Fig. 2 is the detection box of an embodiment of the present invention Chinese medicine experimental animal fixing device and the structural representation of fixed part.As can be seen from Figure 1, medical experiment animal fixing device provided by the invention comprises detection box 1 and fixed part 2, as can be seen from Figure 2, detect box 1 to comprise at the bottom of box 11 and the sidewall that upwards extended by box feather edge as 14 and 16, at the bottom of box and sidewall jointly surround one for accommodating the receiving space of animal, at the bottom of box, 11 are provided with the detection zone 12 that a light conducting stimulates or pain stimulates, and fixed part 2 is arranged at the sidewall surfaces of detection box for being fixed in detection zone 12 by the limbs to be detected of animal.
Particularly, fixed part 2 comprises two fence, 21,22 and fixing band 23, two fence 21 and 22 are oppositely arranged on respectively and detect on box sidewall as being separately positioned on sidewall 14 and 16, fence 21 comprises two montants 211 erect and the many cross bars 212 be fixed on perpendicular to montant between two montants, cross bar 212 is arranged between two montants equidistantly, and the montant 211 in fence is perpendicular to box baseplane.The two ends of fixing band 23 are individually fixed on two fence 21,22, and the middle part of fixing band 23 is provided with magic tape 24, and magic tape 24 bonds rear formation one receiving space, for binding the abdominal part of animal and making the extremity of animal rest in detection zone 12.The two ends of fixing band 23 are directly bound to respectively on the cross bar on two fence, by the cross bar that fixing band is bundled in differing heights adjusting the level altitude of animal.
Fig. 3 is the structural representation that an embodiment of the present invention comprises the medical experiment animal fixing device of support component; Medical experiment animal fixing device provided by the invention comprises detection box 1 and fixed part 2, also comprises for supporting the support component 3 detecting box 1.
Fig. 4 is the structural representation of support component 3 in an embodiment of the present invention; The structural representation of support column in Fig. 5 an embodiment of the present invention.As can be seen from Fig. 4 and Fig. 5, support component 3 comprises cushion block 31 and support column 32, support column 32 comprises the first support column 321 and the first support column 322, one end that cushion block 31 is connected with the first support column 321 offers screwed hole (not shown), one end that first support column 321 is connected with cushion block is provided with the external screw thread (external thread length is L1) coordinated with cushion block screwed hole, the other end that first support column 321 is connected with the second support column 322 offers screwed hole (not shown), one end that second support column 322 is connected with the first support column 321 is provided with the external screw thread (external thread length is L2) coordinated with this screwed hole, first support column and cushion block are threaded connection, first support column and the second support column are threaded connection.
When coordinating burning pain stimulation instrument to use this animal fixing device, first this animal fixing device being assembled, after burning pain stimulation instrument is connected power source, thermostimulation rod being arranged on below detection zone; Animal is detected in box as white mice or rabbit are placed on, then a receiving space is formed by after the magic tape bonding in fixing band, for binding the abdominal part of animal and making the extremity of animal stop in the detection, then open thermostimulation rod, light transmission detection zone is irradiated to the limbs to be detected of animal.In experimentation, even if animal can lift foot due to self-shield reaction, but tightly fixed due to animal, therefore can not occur to change position or movement, maintain experiment continue carry out.
Animal fixing device of the present invention and conventional self-built animal device are carried out the comparison of experiment effect, result is as follows:
Self-built animal experiment device capable, needs prepare raw material and build, estimates 1 week used time.In testing process, ANIMAL PAIN changes position, movement after stimulating, and causes experiment cannot continue to carry out, need repeatedly readjust animal position, test always more than about 1 week consuming time.
But according to animal fixing device of the present invention, within 15 minutes, this animal fixing device can be assembled, within 2 minutes, can animal be fixed, and make its limbs to be measured be fixed in detection zone, within 10 minutes, automatically detect.About 30 minutes consuming time of aforesaid operations.
Result shows that laboratory animal device provided by the invention is simple, and be easy to assembling, can fix animal limbs to be detected and be positioned at detection zone in experimentation, it is time saving and energy saving to test.
The present invention originally will need self manufacture without unified and each experiment and cannot allow laboratory animal detect the limbs animal device be fixed in particular detection region be designed to unified, can simple and easyly assemble, simple to operate, laboratory animal can be allowed simultaneously to detect limbs and to be fixed on animal fixing device in particular detection region, can experimentally actual needs apparatus for assembling whenever and wherever possible, simultaneously can fix laboratory animal, avoid it to move or changing position, cause experiment to stop.Make experiment time saving and energy saving, simple.Laboratory animal device provided by the invention is also reusable, to reduce unnecessary waste.In addition, in transportation, burning pain stimulation instrument main frame can be put into, be convenient in transportation, protect burning pain stimulation instrument main frame, avoid it to be collided.
The above embodiment only have expressed several embodiment of the present invention, and it describes comparatively concrete and detailed, but therefore can not be interpreted as the restriction to the scope of the claims of the present invention.It should be pointed out that for the person of ordinary skill of the art, without departing from the inventive concept of the premise, can also make some distortion and improvement, these all belong to protection scope of the present invention.Therefore, the protection domain of patent of the present invention should be as the criterion with claims.

Claims (10)

1. a medical experiment animal fixing device, it is characterized in that, comprise and detect box and fixed part, the sidewall that described detection box to comprise at the bottom of box and upwards extends along box feather edge, at the bottom of described box and described sidewall jointly surround one for accommodating the receiving space of animal, be provided with the detection zone that at least one light conducting stimulates or pain stimulates at the bottom of described box, described fixed part is arranged at the box basal surface of described detection box or sidewall surfaces for the limbs to be detected of animal are fixed on described detection zone.
2. medical experiment animal fixing device as claimed in claim 1, is characterized in that, described animal fixing device is for coordinating the use of the instrument providing described photostimulation or described pain to stimulate.
3. a medical experiment animal fixing device as claimed in claim 1, is characterized in that, the material of described detection zone is float glass.
4. a medical experiment animal fixing device as claimed in claim 1, is characterized in that, described fixed part comprises the fixture of fixing band for bondage animal and fixing described fixing band.
5. medical experiment animal fixing device as claimed in claim 4, it is characterized in that, described fixed part comprises at least two fixtures and a fixing band, described fixture is oppositely arranged on the sidewall of described detection box respectively, the two ends of described fixing band are individually fixed on described fixture, described fixing band is provided with magic tape, forms a receiving space, for binding the abdominal part of animal and making the limbs to be detected of animal be fixed in described detection zone after described magic tape bonding.
6. the medical experiment animal fixing device as described in claim 4 or 5, is characterized in that, described fixture is projecting fence on described sidewall, screw or the projection being provided with through hole.
7. medical experiment animal fixing device as claimed in claim 6, is characterized in that, described fixing band is fixed on described fixture by hook, safety buckle or direct mode of binding.
8. medical experiment animal fixing device as claimed in claim 6, is characterized in that, described fence comprises two montants erect and the many cross bars be vertically fixed between two described montants, and described cross bar is arranged between described two montants equidistantly.
9. medical experiment animal fixing device as claimed in claim 8, it is characterized in that, the two ends of described fixing band are directly bound to respectively on the cross bar on two described fence, by the described cross bar that described fixing band is bundled in differing heights adjusting the level altitude of animal.
10. medical experiment animal fixing device as claimed in claim 1, it is characterized in that, described medical experiment animal fixing device comprises the bracing or strutting arrangement for supporting described detection box.
CN201510512181.0A 2015-08-19 2015-08-19 A kind of medical experiment animal fixing device Pending CN105213061A (en)

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Application Number Priority Date Filing Date Title
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106983575A (en) * 2017-03-31 2017-07-28 贾文玉 A kind of multipurpose prevents scratching urgent animal first aid platform and animal inspects fixing means
WO2021068362A1 (en) * 2019-10-12 2021-04-15 中国科学院深圳先进技术研究院 Living body stimulation device and system

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2118502U (en) * 1992-03-21 1992-10-14 中国人民解放军第四军医大学 Hamster hot and pain reaction incubation period measuribng instrument
CN201642409U (en) * 2009-12-08 2010-11-24 上海中医药大学附属龙华医院 Fixing device for experimental animal
CN201906031U (en) * 2010-12-15 2011-07-27 骆振东 Adjustable fixing device for treating small animal
CN202198578U (en) * 2011-08-25 2012-04-25 上海中医药大学附属龙华医院 Heat-pain test device applicable to BME-410C type fully-automatic heat-pain stimulators
CN203154001U (en) * 2013-04-18 2013-08-28 陈新伟 Universal fixing device for animal quarantine treatment
CN203195665U (en) * 2013-05-06 2013-09-18 叶宁 Electromagnetic drive embattling needling pain threshold detector
CN203677301U (en) * 2013-12-24 2014-07-02 成都中医药大学 Animal experiment device capable of changing experiment board
CN203677088U (en) * 2014-01-26 2014-07-02 四川大学华西医院 Compatible fixing device of small animal formation of image
CN104068944A (en) * 2013-03-26 2014-10-01 燕铁斌 Three-dimensional adjustment animal restraining and fixing device and restraining method thereof
CN204121198U (en) * 2014-10-15 2015-01-28 谭曜 A kind of rabbit skin test fixtures

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2118502U (en) * 1992-03-21 1992-10-14 中国人民解放军第四军医大学 Hamster hot and pain reaction incubation period measuribng instrument
CN201642409U (en) * 2009-12-08 2010-11-24 上海中医药大学附属龙华医院 Fixing device for experimental animal
CN201906031U (en) * 2010-12-15 2011-07-27 骆振东 Adjustable fixing device for treating small animal
CN202198578U (en) * 2011-08-25 2012-04-25 上海中医药大学附属龙华医院 Heat-pain test device applicable to BME-410C type fully-automatic heat-pain stimulators
CN104068944A (en) * 2013-03-26 2014-10-01 燕铁斌 Three-dimensional adjustment animal restraining and fixing device and restraining method thereof
CN203154001U (en) * 2013-04-18 2013-08-28 陈新伟 Universal fixing device for animal quarantine treatment
CN203195665U (en) * 2013-05-06 2013-09-18 叶宁 Electromagnetic drive embattling needling pain threshold detector
CN203677301U (en) * 2013-12-24 2014-07-02 成都中医药大学 Animal experiment device capable of changing experiment board
CN203677088U (en) * 2014-01-26 2014-07-02 四川大学华西医院 Compatible fixing device of small animal formation of image
CN204121198U (en) * 2014-10-15 2015-01-28 谭曜 A kind of rabbit skin test fixtures

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106983575A (en) * 2017-03-31 2017-07-28 贾文玉 A kind of multipurpose prevents scratching urgent animal first aid platform and animal inspects fixing means
WO2021068362A1 (en) * 2019-10-12 2021-04-15 中国科学院深圳先进技术研究院 Living body stimulation device and system

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