CN105193952A - Care composition capable of removing undesirable odor of foot and preparation method thereof - Google Patents
Care composition capable of removing undesirable odor of foot and preparation method thereof Download PDFInfo
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- CN105193952A CN105193952A CN201510707887.2A CN201510707887A CN105193952A CN 105193952 A CN105193952 A CN 105193952A CN 201510707887 A CN201510707887 A CN 201510707887A CN 105193952 A CN105193952 A CN 105193952A
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Abstract
The invention discloses a care composition capable of removing undesirable odor of a foot and a preparation method thereof. The care composition comprises the following raw materials: extract of Lobelia taliensis Diels, extract of Bidens pilosa L., extract of Embelia laeta (L.) Mez, extract of celandine, extract of tender leaf of eucommia, extract of Lentinus lepideus Fr., extract of leaf of Decaspermum gracilentum, extract of Phoebe sheareri, sodium azulene sulfonate, potassium chloride, vitamin, cetyl pyridinium chloride, glycerin, saccharin and propylene glycol. Through reasonable combination of the above-mentioned raw materials, the fungus Trichophyton mentagrophytes can be killed, and sweat is allowed to react with the composition on the premise of an unchanged amount of dried sweat at the bottom of the foot after the reaction, so waste excreted through sweat at the bottom of the foot is eliminated, the residual amount of the waste excreted through the sweat is reduced and normal growth of Trichophyton mentagrophytes is hindered; thus, the purpose of prevention and treatment of the undesirable odor of the foot is achieved. The care composition is convenient to use and carry, guarantees continuous medication of a patient, prevents intermittent usage of the care composition and ensures care effect.
Description
Technical field
The present invention relates to nursing practical technique field, especially a kind ofly remove care composition of foot abnormal flavour and preparation method thereof.
Background technology
Foot abnormal flavour is also foot odor, is because arch of the foot sweat gland is many, easily perspires, and removes moisture content, salt exceptionally in perspiration, also containing lactic acid and carbamide.Under hyperhidrosis condition, the antibacterial amount reproduction on foot also decomposes keratoprotein, adds the carbamide in perspiration, lactic acid, will send a kind of stink like this.Cause the arch-criminal of foot abnormal flavour to be a kind of fungus crying tinea alba bacterium, the tinea pedis bacterium namely usually said, it produces unpleasant stench after decomposing skin metabolism thing.
In prior art, the research for foot odor is relatively many, and for this disease of foot odor, development has multi-medicament and care method, and foot bath after preparing water as adopted edible salt, white turnip endure water except foot odor etc.; For another example the patent No. is that 201210196381.6 " a kind of Chinese medicine preparation for the treatment of bad smell of feet and beriberi " comprise following component: aluminium potassium sulfate, Borneolum Syntheticum, Herba Menthae, Moschus, and the weight portion of described raw material is: aluminium potassium sulfate 100-200 part, Borneolum Syntheticum 3-5 part, Herba Menthae 3-8 part, Moschus 1-3 part.Excellent effect, easy to use, safety, effective percentage are high, be convenient for carrying; Do not affect the normal perspiration functions of foot, be harmful to human health; Treatment beriberi effective percentage is up to more than 91%.But Moschus belongs to rare medicinal herbs, cost is high, and price is high, and be not that general common income crowd can the rising of optional consumption, and Moschus is for women, especially anemia of pregnant woman, has certain side effect, and therefore this Chinese medicine preparation extensively can not popularize utilization.
In addition, although the above-mentioned treatment effective percentage of document to foot abnormal flavour about removing foot abnormal flavour medication field of the prior art is high, but be still difficult to radical cure, its reason is that the vitality of this fungus of tinea alba bacterium is stronger, and then cause foot odor again and again, make the worries of foot odor patient be difficult to thorough elimination; And when using said medicine to treat, in out on tours, when to be on home leave etc., its medication is inconvenient, but also the medication of foot odor treatment and nursing can be caused intermittent, and then make nursing cost higher, effect is poor.
Summary of the invention
The technical problem that the present invention solves is to provide a kind ofly removes care composition of foot abnormal flavour and preparation method thereof, the care composition of this removal foot abnormal flavour has good curative effect for foot odor, and the care composition of this removal foot abnormal flavour can facilitate patient's continuous use, improve nursing efficacy, the object thoroughly removing patient suffering can be reached.
For solving the problem, the technical solution adopted in the present invention is as follows:
Remove a care composition for foot abnormal flavour, its material composition with parts by weight is: blood-snow willow extract 1 ~ 20 part, sticky people's grass extract 1 ~ 20 part, Radix embeliae laetae extract 1 ~ 20 part, Herba Chelidonii extract 1 ~ 20 part, Folium Eucommiae ulmoidis extract 1 ~ 20 part, amethyst mushroom extract 1 ~ 20 part, Decaspermum gracilentum (Hance) Merr et Perry leaf extract 1 ~ 20 part, Cortex phoebes sheareri extract 1 ~ 20 part, Sodium Azulenesulfonate 0.005 ~ 0.5 part, 0.1 ~ 3 part, potassium chloride, vitamin C 1 ~ 3 part, cetylpyridinium chloride 0.1 ~ 0.3 part, glycerol 5 ~ 10 parts, 1 ~ 5 part, glucide, propylene glycol 1 ~ 3 part.
Further, described material composition with parts by weight is: blood-snow willow extract 10 parts, sticky people's grass extract 10 parts, Radix embeliae laetae extract 10 parts, Herba Chelidonii extract 10 parts, Folium Eucommiae ulmoidis extract 10 parts, amethyst mushroom extract 10 parts, Decaspermum gracilentum (Hance) Merr et Perry leaf extract 10 parts, Cortex phoebes sheareri extract 10 parts, Sodium Azulenesulfonate 0.3 part, 1 part, potassium chloride, Catergen part, cetylpyridinium chloride 0.2 part, glycerol 7 parts, 3 parts, glucide, propylene glycol 2 parts.
Further, described a kind of care composition removing foot abnormal flavour, can also add hibitane 0.01 ~ 0.03 part, L-Mentholum 0.01 ~ 0.3 part as adjuvant.
Further, described blood-snow willow extract, sticky people's grass extract, amethyst mushroom extract, Decaspermum gracilentum (Hance) Merr et Perry leaf extract, Cortex phoebes sheareri extract, its preparation method is: by blood-snow willow, sticky people's grass, amethyst mushroom, Decaspermum gracilentum (Hance) Merr et Perry leaf, after Cortex phoebes sheareri pretreatment, mixing, obtain mixing medicinal raw material, be placed in boiler, add the clear water relative to its weight 5 ~ 7 times, the temperature of 120 ~ 130 DEG C is adopted to decoct extraction 1 ~ 3 time, each extraction time is 40 ~ 50min, filter, merging filtrate, after being cooled to room temperature again, precipitation process is carried out with the ethanol that mass concentration is 85%, the supernatant obtained takes out, be concentrated into 35 ~ 45%, obtain,
Further, described Radix embeliae laetae extract, Herba Chelidonii extract, its preparation method is: Radix embeliae laetae and Herba Chelidonii are dried, be placed in grinder grind into powder, obtain hybrid medicine powder, adding relative to the mass concentration of its weight 3 ~ 4 times in gained hybrid medicine powder is the ethanol of 52 ~ 55%, adopts ultrasonic frequency to be that 30 ~ 50Hz extracts 10 ~ 20min, filter, obtain solution and get final product;
Further, described Folium Eucommiae ulmoidis extract, its preparation method is: cleaned by Folium Eucommiae ulmoidis after drying, be placed in pulverizer and be ground into coarse powder, take out, be cooled to room temperature, then to be placed in baking oven 80 ~ 85 DEG C of bakings after 20 ~ 30 minutes, be placed in super micron mill and pulverize, cross 100 mesh sieves, obtain powder and get final product;
The preparation method of the care composition of this removal foot abnormal flavour, comprises the following steps:
(1) blood-snow willow extract is prepared, sticky people's grass extract, amethyst mushroom extract, Decaspermum gracilentum (Hance) Merr et Perry leaf extract and Cortex phoebes sheareri extract: by blood-snow willow, sticky people's grass, amethyst mushroom, Decaspermum gracilentum (Hance) Merr et Perry leaf, after Cortex phoebes sheareri pretreatment, mixing, obtain mixing medicinal raw material, be placed in boiler, add the clear water relative to its weight 5 ~ 7 times, the temperature of 120 ~ 130 DEG C is adopted to decoct extraction 1 ~ 3 time, each extraction time is 40 ~ 50min, filter, merging filtrate, after being cooled to room temperature again, precipitation process is carried out with the ethanol that mass concentration is 85%, the supernatant obtained takes out, be concentrated into 35 ~ 45%, obtain,
(2) Radix embeliae laetae extract and Herba Chelidonii extract is prepared: Radix embeliae laetae and Herba Chelidonii are dried, be placed in grinder grind into powder, obtain hybrid medicine powder, adding relative to the mass concentration of its weight 3 ~ 4 times in gained hybrid medicine powder is the ethanol of 52 ~ 55%, ultrasonic frequency is adopted to be that 30 ~ 50Hz extracts 10 ~ 20min, filter, obtain solution and get final product;
(3) Folium Eucommiae ulmoidis extract is prepared: cleaned by Folium Eucommiae ulmoidis after drying, be placed in pulverizer and be ground into coarse powder, take out, be cooled to room temperature, then be placed in baking oven 80 ~ 85 DEG C of bakings after 20 ~ 30 minutes, be placed in super micron mill and pulverize, cross 100 mesh sieves, obtain powder and get final product;
(4) raw material mixing: by potassium chloride, vitamin C, hibitane, cetylpyridinium chloride, L-Mentholum, glycerol 7 parts, glucide, propylene glycol, Sodium Azulenesulfonate, hibitane, the mixing of L-Mentholum in dispensing canister, add the blood-snow willow extract obtained by above-mentioned steps (1) to (3), sticky people's grass extract, amethyst mushroom extract, Decaspermum gracilentum (Hance) Merr et Perry leaf extract, Cortex phoebes sheareri extract, Radix embeliae laetae extract, Herba Chelidonii extract, Folium Eucommiae ulmoidis extract again, stir, obtain raw mixture;
(5) above-mentioned steps (4) gained raw mixture is placed in ultrasound wave dispersing apparatus and carries out ultrasonic disperse process, the care composition removing foot abnormal flavour can be obtained, the care composition of this removal foot abnormal flavour is carried out the division of dosage each time according to the order of severity of conditions of patients, according to described various different dosage, the care composition of this removal foot abnormal flavour is distributed into independent fractional pack again, packaging indicates dose, after patient determines the dosage of oneself according to the state of an illness, different packagings is selected again according to required dosage, not only easy to use, and it is easy to carry.
Further, the process conditions that described raw mixture ultrasound wave dispersing apparatus carries out ultrasonic disperse process are: first ultrasonic frequency is adjusted to 60 ~ 100Hz, process 30 ~ 50s, then to adjust ultrasonic frequency be 130 ~ 150Hz, process 10 ~ 20s.
Selected by the present invention, the present Research of Chinese crude drug is as follows:
Blood-snow willow: [source] campanulaceae blood-snow willow LobeliataliensisDiels, is used as medicine with root.
[nature and flavor] are pungent, cool, slightly poisonous.[function cures mainly] anti-inflammatory analgetic, sterilization; Cure mainly malaria.
Sticky people's grass: [source] pulse family glues people's grass Desmodiumgangeticum (L.) DC., is used as medicine with root.[nature and flavor] are sweet, micro-pungent, flat.[function cures mainly] antiinflammatory, sterilization, menstruction regulating and pain relieving; Cure mainly uterine prolapse, proctoptosis, stomachache, amenorrhea, psoriasis, neurodermatitis.
Radix embeliae laetae: the root that [source] is Myrsinacea plant Fructus embeliae laetae and branch and leaf.Root, the whole year can adopt, and cleans section, dries.[nature and flavor] acid; Puckery; Cool in nature.[function cures mainly] heat-clearing and toxic substances removing; Dissipating blood stasis stops blooding.
Main pharyngitis; Gingiva bleeding gingival hemorrhage; Dysentery; Have loose bowels; Furuncle ulcer; Skin pruritus; Swelling and pain of hemorrhoid; Traumatic injury.
Herba Chelidonii: [nature and flavor] are bitter, cool.Poisonous.[function cures mainly] heat-clearing and toxic substances removing, pain relieving, cough-relieving.For gastritis, gastric ulcer, stomachache, enteritis, dysentery, jaundice, chronic tracheitis, pertussis; Paddy-field dermatitis is controlled in external, insect-bite.
Folium Eucommiae ulmoidis: [source] is the nascent tender leaf of the Eucommiaceae plant Cortex Eucommiae.[nature and flavor] are sweet; Property is put down.[function cures mainly] tonify deficiency promotes the production of body fluid; Removing toxic substances; Hemostasis.Main physical weakness; Swelling and pain of hemorrhoid; Have blood in stool.
Amethyst mushroom: [source] medical material Ji Yuan: be the sporophore of Bai Mo section fungus Lepista mucla (Bull.:Fr.) Cooke.[nature and flavor] are sweet; Property is put down.[return through] spleen channel.[function cures mainly] invigorating the spleen to clear away damp pathogen.
Decaspermum gracilentum (Hance) Merr et Perry leaf: [source] medical material Ji Yuan: be the leaf of myrtle Decaspermum gracilentum (Hance) Merr et Perry.[nature and flavor] acrid in the mouth; Bitter; Property is put down.[function cures mainly] regulating QI to expel dampness; Removing toxic substances parasite killing.Main humidity hysteresis abdominal distention; Dysentery; Eczema; Scabies.
Cortex phoebes sheareri: [source] Lauraceae Phoebe Nees Cortex phoebes sheareri Phoebesheareri (Hemsl.) Gamble, is used as medicine with leaf, root.The four seasons can adopt.[nature and flavor] are pungent, temperature.[function cures mainly] leaf: warming middle-JIAO is regulated the flow of vital energy.For beriberi edema, abdominal distention.Root: removing blood stasis to reduce swelling.For traumatic injury.
Compared with prior art, technique effect of the present invention is embodied in:
(1) the present invention passes through blood-snow willow extract, sticky people's grass extract, amethyst mushroom extract, Decaspermum gracilentum (Hance) Merr et Perry leaf extract, Cortex phoebes sheareri extract, Radix embeliae laetae extract, Herba Chelidonii extract, Folium Eucommiae ulmoidis extract, potassium chloride, vitamin C, cetylpyridinium chloride, glycerol 7 parts, glucide, propylene glycol, Sodium Azulenesulfonate carries out rational compatible combination, this fungus of tinea alba bacterium can be killed, and under the prerequisite that the amount of draining off of sole can be made constant, the perspiration flowed out can be had an effect with compositions, and then the refuse that after reaching reaction, elimination sole perspiration excretes, the garbage that reduction perspiration excretes is in the residual quantity of sole, hinder tinea alba bacterium normal growth, and then reach the object of control foot abnormal flavour.
(2) the present invention is in conjunction with the ultrasonic mixed processing in preparation process, the fusion degree each other of various ingredient is under control, improve the contact rate of ingredient, and then make the cooperative effect between various ingredient obvious, and promote the cooperative effect of medicine, reduce the consumption of ingredient raw material, reduce cost.
(3) care composition of this removal foot abnormal flavour is carried out the division of dosage each time by the present invention according to the order of severity of conditions of patients, according to described various different dosage, the care composition of this removal foot abnormal flavour is distributed into independent fractional pack again, packaging indicates dose, after patient determines the dosage of oneself according to the state of an illness, different packagings is selected again according to required dosage, not only easy to use, and it is easy to carry, ensure that patient is during medication nursing, such as in out on tours, when to be on home leave etc., can continuous use, avoid the desultory situation of foot abnormal flavour treatment and nursing medication, greatly ensure that nursing efficacy, the object thoroughly removing patient suffering can be reached.
Detailed description of the invention
Below in conjunction with concrete embodiment, technical scheme of the present invention is further described in detail, but claimed scope is not only confined to done description.
Embodiment 1:
Remove a care composition for foot abnormal flavour, its material composition with parts by weight is: blood-snow willow extract 1 part, sticky people's grass extract 1 part, Radix embeliae laetae extract 1 part, Herba Chelidonii extract 1 part, Folium Eucommiae ulmoidis extract 1 part, amethyst mushroom extract 1 part, Decaspermum gracilentum (Hance) Merr et Perry leaf extract 1 part, Cortex phoebes sheareri extract 1 part, Sodium Azulenesulfonate 0.005 part, 0.1 part, potassium chloride, vitamin C 1 part, cetylpyridinium chloride 0.1 part, glycerol 5 parts, 1 part, glucide, propylene glycol 1 part; Add hibitane 0.01 part, L-Mentholum 0.01 part as adjuvant.
Wherein, described blood-snow willow extract, sticky people's grass extract, amethyst mushroom extract, Decaspermum gracilentum (Hance) Merr et Perry leaf extract, Cortex phoebes sheareri extract, its preparation method is: by blood-snow willow, sticky people's grass, amethyst mushroom, Decaspermum gracilentum (Hance) Merr et Perry leaf, after Cortex phoebes sheareri pretreatment, mixing, obtain mixing medicinal raw material, be placed in boiler, add the clear water relative to its weight 5 times, the temperature of 120 DEG C is adopted to decoct extraction 1 time, each extraction time is 40min, filter, merging filtrate, after being cooled to room temperature again, precipitation process is carried out with the ethanol that mass concentration is 85%, the supernatant obtained takes out, be concentrated into 35%, obtain, described Radix embeliae laetae extract, Herba Chelidonii extract, its preparation method is: Radix embeliae laetae and Herba Chelidonii are dried, be placed in grinder grind into powder, obtain hybrid medicine powder, adding relative to the mass concentration of its weight 3 ~ 4 times in gained hybrid medicine powder is the ethanol of 52%, adopt ultrasonic frequency to be that 30Hz extracts 10min, filter, obtain solution and get final product, described Folium Eucommiae ulmoidis extract, its preparation method is: cleaned by Folium Eucommiae ulmoidis after drying, be placed in pulverizer and be ground into coarse powder, take out, be cooled to room temperature, then to be placed in baking oven 80 DEG C of bakings after 20 minutes, be placed in super micron mill and pulverize, cross 100 mesh sieves, obtain powder and get final product,
The preparation method of the care composition of this removal foot abnormal flavour is:
(1) blood-snow willow extract is prepared, sticky people's grass extract, amethyst mushroom extract, Decaspermum gracilentum (Hance) Merr et Perry leaf extract and Cortex phoebes sheareri extract: by blood-snow willow, sticky people's grass, amethyst mushroom, Decaspermum gracilentum (Hance) Merr et Perry leaf, after Cortex phoebes sheareri pretreatment, mixing, obtain mixing medicinal raw material, be placed in boiler, add the clear water relative to its weight 5 times, the temperature of 120 DEG C is adopted to decoct extraction 1 time, each extraction time is 40min, filter, merging filtrate, after being cooled to room temperature again, precipitation process is carried out with the ethanol that mass concentration is 85%, the supernatant obtained takes out, be concentrated into 35%, obtain,
(2) Radix embeliae laetae extract and Herba Chelidonii extract is prepared: Radix embeliae laetae and Herba Chelidonii are dried, be placed in grinder grind into powder, obtain hybrid medicine powder, adding relative to the mass concentration of its weight 3 times in gained hybrid medicine powder is the ethanol of 52%, ultrasonic frequency is adopted to be that 30Hz extracts 10min, filter, obtain solution and get final product;
(3) prepare Folium Eucommiae ulmoidis extract: cleaned by Folium Eucommiae ulmoidis after drying, be placed in pulverizer and be ground into coarse powder, take out, be cooled to room temperature, then to be placed in baking oven 80 DEG C of bakings after 20 minutes, be placed in super micron mill and pulverize, cross 100 mesh sieves, obtain powder and get final product;
(4) raw material mixing: by potassium chloride, vitamin C, hibitane, cetylpyridinium chloride, L-Mentholum, glycerol, glucide, propylene glycol, Sodium Azulenesulfonate, hibitane, the mixing of L-Mentholum in dispensing canister, add the blood-snow willow extract obtained by above-mentioned steps (1) to (3), sticky people's grass extract, amethyst mushroom extract, Decaspermum gracilentum (Hance) Merr et Perry leaf extract, Cortex phoebes sheareri extract, Radix embeliae laetae extract, Herba Chelidonii extract, Folium Eucommiae ulmoidis extract again, stir, obtain raw mixture;
(5) above-mentioned steps (4) gained raw mixture is placed in ultrasound wave dispersing apparatus and carries out ultrasonic disperse process: first ultrasonic frequency is adjusted to 60Hz, process 30s, adjusting ultrasonic frequency is again 130Hz, process 10s, the care composition removing foot abnormal flavour can be obtained, the care composition of this removal foot abnormal flavour is carried out the division of dosage each time according to the order of severity of conditions of patients, according to described various different dosage, the care composition of this removal foot abnormal flavour is distributed into independent fractional pack again, packaging indicates dose, after patient determines the dosage of oneself according to the state of an illness, different packagings is selected again according to required dosage, not only easy to use, and it is easy to carry.
Embodiment 2:
Remove a care composition for foot abnormal flavour, its material composition with parts by weight is: blood-snow willow extract 10.5 parts, sticky people's grass extract 10.5 parts, Radix embeliae laetae extract 10.5 parts, Herba Chelidonii extract 10.5 parts, Folium Eucommiae ulmoidis extract 10.5 parts, amethyst mushroom extract 10.5 parts, Decaspermum gracilentum (Hance) Merr et Perry leaf extract 10.5 parts, Cortex phoebes sheareri extract 10.5 parts, Sodium Azulenesulfonate 0.2525 part, 1.55 parts, potassium chloride, Catergen part, cetylpyridinium chloride 0.2 part, glycerol 7.5 parts, 3 parts, glucide, propylene glycol 2 parts; Add hibitane 0.02 part, L-Mentholum 0.155 part as adjuvant.
Wherein, described blood-snow willow extract, sticky people's grass extract, amethyst mushroom extract, Decaspermum gracilentum (Hance) Merr et Perry leaf extract, Cortex phoebes sheareri extract, its preparation method is: by blood-snow willow, sticky people's grass, amethyst mushroom, Decaspermum gracilentum (Hance) Merr et Perry leaf, after Cortex phoebes sheareri pretreatment, mixing, obtain mixing medicinal raw material, be placed in boiler, add the clear water relative to its weight 6 times, the temperature of 125 DEG C is adopted to decoct extraction 2 times, each extraction time is 45min, filter, merging filtrate, after being cooled to room temperature again, precipitation process is carried out with the ethanol that mass concentration is 85%, the supernatant obtained takes out, be concentrated into 40%, obtain, described Radix embeliae laetae extract, Herba Chelidonii extract, its preparation method is: Radix embeliae laetae and Herba Chelidonii are dried, be placed in grinder grind into powder, obtain hybrid medicine powder, adding relative to the mass concentration of its weight 3.5 times in gained hybrid medicine powder is the ethanol of 53.5%, adopt ultrasonic frequency to be that 40Hz extracts 15min, filter, obtain solution and get final product, described Folium Eucommiae ulmoidis extract, its preparation method is: cleaned by Folium Eucommiae ulmoidis after drying, be placed in pulverizer and be ground into coarse powder, take out, be cooled to room temperature, then to be placed in baking oven 82.5 DEG C of bakings after 25 minutes, be placed in super micron mill and pulverize, cross 100 mesh sieves, obtain powder and get final product,
The preparation method of the care composition of this removal foot abnormal flavour is:
(1) blood-snow willow extract is prepared, sticky people's grass extract, amethyst mushroom extract, Decaspermum gracilentum (Hance) Merr et Perry leaf extract and Cortex phoebes sheareri extract: by blood-snow willow, sticky people's grass, amethyst mushroom, Decaspermum gracilentum (Hance) Merr et Perry leaf, after Cortex phoebes sheareri pretreatment, mixing, obtain mixing medicinal raw material, be placed in boiler, add the clear water relative to its weight 6 times, the temperature of 125 DEG C is adopted to decoct extraction 2 times, each extraction time is 45min, filter, merging filtrate, after being cooled to room temperature again, precipitation process is carried out with the ethanol that mass concentration is 85%, the supernatant obtained takes out, be concentrated into 40%, obtain,
(2) Radix embeliae laetae extract and Herba Chelidonii extract is prepared: Radix embeliae laetae and Herba Chelidonii are dried, be placed in grinder grind into powder, obtain hybrid medicine powder, adding relative to the mass concentration of its weight 3.5 times in gained hybrid medicine powder is the ethanol of 53.5%, ultrasonic frequency is adopted to be that 40Hz extracts 15min, filter, obtain solution and get final product;
(3) prepare Folium Eucommiae ulmoidis extract: cleaned by Folium Eucommiae ulmoidis after drying, be placed in pulverizer and be ground into coarse powder, take out, be cooled to room temperature, then to be placed in baking oven 82.5 DEG C of bakings after 25 minutes, be placed in super micron mill and pulverize, cross 100 mesh sieves, obtain powder and get final product;
(4) raw material mixing: by potassium chloride, vitamin C, hibitane, cetylpyridinium chloride, L-Mentholum, glycerol 7 parts, glucide, propylene glycol, Sodium Azulenesulfonate, hibitane, the mixing of L-Mentholum in dispensing canister, add the blood-snow willow extract obtained by above-mentioned steps (1) to (3), sticky people's grass extract, amethyst mushroom extract, Decaspermum gracilentum (Hance) Merr et Perry leaf extract, Cortex phoebes sheareri extract, Radix embeliae laetae extract, Herba Chelidonii extract, Folium Eucommiae ulmoidis extract again, stir, obtain raw mixture;
(5) above-mentioned steps (4) gained raw mixture is placed in ultrasound wave dispersing apparatus and carries out ultrasonic disperse process: first ultrasonic frequency is adjusted to 80Hz, process 40s, adjusting ultrasonic frequency is again 140Hz, process 15s, the care composition removing foot abnormal flavour can be obtained, the care composition of this removal foot abnormal flavour is carried out the division of dosage each time according to the order of severity of conditions of patients, according to described various different dosage, the care composition of this removal foot abnormal flavour is distributed into independent fractional pack again, packaging indicates dose, after patient determines the dosage of oneself according to the state of an illness, different packagings is selected again according to required dosage, not only easy to use, and it is easy to carry.
Embodiment 3:
Remove a care composition for foot abnormal flavour, its material composition with parts by weight is: blood-snow willow extract 20 parts, sticky people's grass extract 20 parts, Radix embeliae laetae extract 20 parts, Herba Chelidonii extract 20 parts, Folium Eucommiae ulmoidis extract 20 parts, amethyst mushroom extract 20 parts, Decaspermum gracilentum (Hance) Merr et Perry leaf extract 20 parts, Cortex phoebes sheareri extract 20 parts, Sodium Azulenesulfonate 0.5 part, 3 parts, potassium chloride, vitamin C 3 parts, cetylpyridinium chloride 0.3 part, glycerol 10 parts, 5 parts, glucide, propylene glycol 3 parts; Add hibitane 0.03 part, L-Mentholum 0.3 part as adjuvant.
Wherein, described blood-snow willow extract, sticky people's grass extract, amethyst mushroom extract, Decaspermum gracilentum (Hance) Merr et Perry leaf extract, Cortex phoebes sheareri extract, its preparation method is: by blood-snow willow, sticky people's grass, amethyst mushroom, Decaspermum gracilentum (Hance) Merr et Perry leaf, after Cortex phoebes sheareri pretreatment, mixing, obtain mixing medicinal raw material, be placed in boiler, add the clear water relative to its weight 7 times, the temperature of 130 DEG C is adopted to decoct extraction 3 times, each extraction time is 50min, filter, merging filtrate, after being cooled to room temperature again, precipitation process is carried out with the ethanol that mass concentration is 85%, the supernatant obtained takes out, be concentrated into 45%, obtain, described Radix embeliae laetae extract, Herba Chelidonii extract, its preparation method is: Radix embeliae laetae and Herba Chelidonii are dried, be placed in grinder grind into powder, obtain hybrid medicine powder, adding relative to the mass concentration of its weight 4 times in gained hybrid medicine powder is the ethanol of 55%, adopt ultrasonic frequency to be that 50Hz extracts 20min, filter, obtain solution and get final product, described Folium Eucommiae ulmoidis extract, its preparation method is: cleaned by Folium Eucommiae ulmoidis after drying, be placed in pulverizer and be ground into coarse powder, take out, be cooled to room temperature, then to be placed in baking oven 85 DEG C of bakings after 30 minutes, be placed in super micron mill and pulverize, cross 100 mesh sieves, obtain powder and get final product,
The preparation method of the care composition of this removal foot abnormal flavour is:
(1) blood-snow willow extract is prepared, sticky people's grass extract, amethyst mushroom extract, Decaspermum gracilentum (Hance) Merr et Perry leaf extract and Cortex phoebes sheareri extract: by blood-snow willow, sticky people's grass, amethyst mushroom, Decaspermum gracilentum (Hance) Merr et Perry leaf, after Cortex phoebes sheareri pretreatment, mixing, obtain mixing medicinal raw material, be placed in boiler, add the clear water relative to its weight 7 times, the temperature of 130 DEG C is adopted to decoct extraction 3 times, each extraction time is 50min, filter, merging filtrate, after being cooled to room temperature again, precipitation process is carried out with the ethanol that mass concentration is 85%, the supernatant obtained takes out, be concentrated into 45%, obtain,
(2) Radix embeliae laetae extract and Herba Chelidonii extract is prepared: Radix embeliae laetae and Herba Chelidonii are dried, be placed in grinder grind into powder, obtain hybrid medicine powder, adding relative to the mass concentration of its weight 4 times in gained hybrid medicine powder is the ethanol of 55%, ultrasonic frequency is adopted to be that 50Hz extracts 20min, filter, obtain solution and get final product;
(3) prepare Folium Eucommiae ulmoidis extract: cleaned by Folium Eucommiae ulmoidis after drying, be placed in pulverizer and be ground into coarse powder, take out, be cooled to room temperature, then to be placed in baking oven 85 DEG C of bakings after 30 minutes, be placed in super micron mill and pulverize, cross 100 mesh sieves, obtain powder and get final product;
(4) raw material mixing: by potassium chloride, vitamin C, hibitane, cetylpyridinium chloride, L-Mentholum, glycerol 7 parts, glucide, propylene glycol, Sodium Azulenesulfonate, hibitane, the mixing of L-Mentholum in dispensing canister, add the blood-snow willow extract obtained by above-mentioned steps (1) to (3), sticky people's grass extract, amethyst mushroom extract, Decaspermum gracilentum (Hance) Merr et Perry leaf extract, Cortex phoebes sheareri extract, Radix embeliae laetae extract, Herba Chelidonii extract, Folium Eucommiae ulmoidis extract again, stir, obtain raw mixture;
(5) above-mentioned steps (4) gained raw mixture is placed in ultrasound wave dispersing apparatus and carries out ultrasonic disperse process: first ultrasonic frequency is adjusted to 100Hz, process 50s, adjusting ultrasonic frequency is again 150Hz, process 20s, the care composition removing foot abnormal flavour can be obtained, the care composition of this removal foot abnormal flavour is carried out the division of dosage each time according to the order of severity of conditions of patients, according to described various different dosage, the care composition of this removal foot abnormal flavour is distributed into independent fractional pack again, packaging indicates dose, after patient determines the dosage of oneself according to the state of an illness, different packagings is selected again according to required dosage, not only easy to use, and it is easy to carry.
Embodiment 4:
Remove a care composition for foot abnormal flavour, its material composition with parts by weight is: blood-snow willow extract 10 parts, sticky people's grass extract 10 parts, Radix embeliae laetae extract 10 parts, Herba Chelidonii extract 10 parts, Folium Eucommiae ulmoidis extract 10 parts, amethyst mushroom extract 10 parts, Decaspermum gracilentum (Hance) Merr et Perry leaf extract 10 parts, Cortex phoebes sheareri extract 10 parts, Sodium Azulenesulfonate 0.3 part, 1 part, potassium chloride, Catergen part, cetylpyridinium chloride 0.2 part, glycerol 7 parts, 3 parts, glucide, propylene glycol 2 parts; Add hibitane 0.018 part, L-Mentholum 0.15 part as adjuvant.
Wherein, described blood-snow willow extract, sticky people's grass extract, amethyst mushroom extract, Decaspermum gracilentum (Hance) Merr et Perry leaf extract, Cortex phoebes sheareri extract, its preparation method is: by blood-snow willow, sticky people's grass, amethyst mushroom, Decaspermum gracilentum (Hance) Merr et Perry leaf, after Cortex phoebes sheareri pretreatment, mixing, obtain mixing medicinal raw material, be placed in boiler, add the clear water relative to its weight 6 times, the temperature of 125 DEG C is adopted to decoct extraction 2 times, each extraction time is 45min, filter, merging filtrate, after being cooled to room temperature again, precipitation process is carried out with the ethanol that mass concentration is 85%, the supernatant obtained takes out, be concentrated into 40%, obtain, described Radix embeliae laetae extract, Herba Chelidonii extract, its preparation method is: Radix embeliae laetae and Herba Chelidonii are dried, be placed in grinder grind into powder, obtain hybrid medicine powder, adding relative to the mass concentration of its weight 3.5 times in gained hybrid medicine powder is the ethanol of 53.5%, adopt ultrasonic frequency to be that 40Hz extracts 15min, filter, obtain solution and get final product, described Folium Eucommiae ulmoidis extract, its preparation method is: cleaned by Folium Eucommiae ulmoidis after drying, be placed in pulverizer and be ground into coarse powder, take out, be cooled to room temperature, then to be placed in baking oven 82.5 DEG C of bakings after 25 minutes, be placed in super micron mill and pulverize, cross 100 mesh sieves, obtain powder and get final product,
The preparation method of the care composition of this removal foot abnormal flavour is:
(1) blood-snow willow extract is prepared, sticky people's grass extract, amethyst mushroom extract, Decaspermum gracilentum (Hance) Merr et Perry leaf extract and Cortex phoebes sheareri extract: by blood-snow willow, sticky people's grass, amethyst mushroom, Decaspermum gracilentum (Hance) Merr et Perry leaf, after Cortex phoebes sheareri pretreatment, mixing, obtain mixing medicinal raw material, be placed in boiler, add the clear water relative to its weight 6 times, the temperature of 125 DEG C is adopted to decoct extraction 2 times, each extraction time is 45min, filter, merging filtrate, after being cooled to room temperature again, precipitation process is carried out with the ethanol that mass concentration is 85%, the supernatant obtained takes out, be concentrated into 40%, obtain,
(2) Radix embeliae laetae extract and Herba Chelidonii extract is prepared: Radix embeliae laetae and Herba Chelidonii are dried, be placed in grinder grind into powder, obtain hybrid medicine powder, adding relative to the mass concentration of its weight 3.5 times in gained hybrid medicine powder is the ethanol of 53.5%, ultrasonic frequency is adopted to be that 40Hz extracts 15min, filter, obtain solution and get final product;
(3) prepare Folium Eucommiae ulmoidis extract: cleaned by Folium Eucommiae ulmoidis after drying, be placed in pulverizer and be ground into coarse powder, take out, be cooled to room temperature, then to be placed in baking oven 82.5 DEG C of bakings after 25 minutes, be placed in super micron mill and pulverize, cross 100 mesh sieves, obtain powder and get final product;
(4) raw material mixing: by potassium chloride, vitamin C, hibitane, cetylpyridinium chloride, L-Mentholum, glycerol 7 parts, glucide, propylene glycol, Sodium Azulenesulfonate, hibitane, the mixing of L-Mentholum in dispensing canister, add the blood-snow willow extract obtained by above-mentioned steps (1) to (3), sticky people's grass extract, amethyst mushroom extract, Decaspermum gracilentum (Hance) Merr et Perry leaf extract, Cortex phoebes sheareri extract, Radix embeliae laetae extract, Herba Chelidonii extract, Folium Eucommiae ulmoidis extract again, stir, obtain raw mixture;
(5) above-mentioned steps (4) gained raw mixture is placed in ultrasound wave dispersing apparatus and carries out ultrasonic disperse process: first ultrasonic frequency is adjusted to 80Hz, process 40s, adjusting ultrasonic frequency is again 140Hz, process 15s, the care composition removing foot abnormal flavour can be obtained, the care composition of this removal foot abnormal flavour is carried out the division of dosage each time according to the order of severity of conditions of patients, according to described various different dosage, the care composition of this removal foot abnormal flavour is distributed into independent fractional pack again, packaging indicates dose, after patient determines the dosage of oneself according to the state of an illness, different packagings is selected again according to required dosage, not only easy to use, and it is easy to carry.
Clinical efficacy is verified
1, clinical data:
In the foot abnormal flavour patient accepted for medical treatment during certain hospital year January in January, 2011 to 2014, random selecting 300 routine foot abnormal flavour patients, wherein men and women half and half, minimum 16 years old of patient age, maximum 68 years old, cardinal symptom had: sweaty foot is many, pruritus pain, play pustule, get blister, fester, stench, desquamation, redness etc.
2, Therapeutic Method:
After foot cleans up every day by method 1, patient just before going to bed, get the care composition of removal foot abnormal flavour prepared by the embodiment of the present invention 2, uniform application is in affected part, and after drying in the air 8 ~ 10 minutes, medicine can absorb completely, and using continuously 7th is a course for the treatment of, totally four courses for the treatment of.
3, criterion of therapeutical effect: recovery from illness: all clinical symptom disappearance such as foot pruritus, foot abnormal flavour, sweaty foot; Effective: the clinical symptom reliefs such as foot pruritus, foot abnormal flavour, sweaty foot; Invalid: the clinical symptoms such as foot pruritus, foot abnormal flavour, sweaty foot are without alleviation.
4, therapeutic outcome statistics:
In 300 routine foot abnormal flavour patients, wherein have 263 people to fully recover after 2 courses for the treatment of of medication, medication has 284 people's recoveries from illness after 3 courses for the treatment of, and medication has 297 people's recoveries from illness after 4 courses for the treatment of, only 3 people are invalid, and cure rate reaches 99%
Model case:
1, Lee, man, 46 years old, suffer from beriberi nearly 10 years, foot often perspired, and desquamation also with stench, is very itched unbearably during outbreak, festered between toe, and summer is serious, and winter slightly takes a turn for the better.Once repeatedly used various Chinese medicine and western medicine, therapeutic effect is undesirable, continuous recurrent exerbation.After 1 course for the treatment of of care composition of continuous use removal foot of the present invention abnormal flavour, foot pruritus transference cure, after 2 courses for the treatment of, the clinical symptoms such as foot abnormal flavour, sweaty foot also disappear, symptom of festering between toe also disappears, and continuation medication was fully recovered after 3 courses for the treatment of, follows up a case by regular visits to without recurrence after 1 year.
2, bavin, man, 55 years old, suffer from beriberi nearly 20 years, foot often perspired, and with stench, very itches unbearably, fester between toe during outbreak, and summer is serious, and winter slightly takes a turn for the better.Once repeatedly used various Chinese medicine and western medicine, therapeutic effect is undesirable, continuous recurrent exerbation.After 1 course for the treatment of of care composition of continuous use removal foot of the present invention abnormal flavour, foot pruritus transference cure, after 2 courses for the treatment of, the clinical symptoms such as foot abnormal flavour, sweaty foot also disappear, after 3 courses for the treatment of, and the skin rehabilitation of festering between toe, continuation medication was fully recovered after 4 courses for the treatment of, followed up a case by regular visits to without recurrence after 1 year.
Last it is noted that above embodiment is only in order to illustrate technical scheme of the present invention, be not intended to limit; Although with reference to previous embodiment to invention has been detailed description, those of ordinary skill in the art is to be understood that: it still can be modified to the technical scheme described in previous embodiment, or carries out equivalent replacement to wherein portion of techniques feature; And these amendments or replacement, do not make the essence of appropriate technical solution depart from the spirit and scope of embodiment of the present invention technical scheme.
Claims (8)
1. remove the care composition of foot abnormal flavour for one kind, it is characterized in that, its material composition with parts by weight is: blood-snow willow extract 1 ~ 20 part, sticky people's grass extract 1 ~ 20 part, Radix embeliae laetae extract 1 ~ 20 part, Herba Chelidonii extract 1 ~ 20 part, Folium Eucommiae ulmoidis extract 1 ~ 20 part, amethyst mushroom extract 1 ~ 20 part, Decaspermum gracilentum (Hance) Merr et Perry leaf extract 1 ~ 20 part, Cortex phoebes sheareri extract 1 ~ 20 part, Sodium Azulenesulfonate 0.005 ~ 0.5 part, 0.1 ~ 3 part, potassium chloride, vitamin C 1 ~ 3 part, cetylpyridinium chloride 0.1 ~ 0.3 part, glycerol 5 ~ 10 parts, 1 ~ 5 part, glucide, propylene glycol 1 ~ 3 part.
2. a kind of care composition removing foot abnormal flavour as claimed in claim 1, it is characterized in that, described material composition with parts by weight is: blood-snow willow extract 10 parts, sticky people's grass extract 10 parts, Radix embeliae laetae extract 10 parts, Herba Chelidonii extract 10 parts, Folium Eucommiae ulmoidis extract 10 parts, amethyst mushroom extract 10 parts, Decaspermum gracilentum (Hance) Merr et Perry leaf extract 10 parts, Cortex phoebes sheareri extract 10 parts, Sodium Azulenesulfonate 0.3 part, 1 part, potassium chloride, Catergen part, cetylpyridinium chloride 0.2 part, glycerol 7 parts, 3 parts, glucide, propylene glycol 2 parts.
3. a kind of care composition removing foot abnormal flavour as claimed in claim 1 or 2, is characterized in that, can also add hibitane 0.01 ~ 0.03 part, L-Mentholum 0.01 ~ 0.3 part as adjuvant.
4. a kind of care composition removing foot abnormal flavour as claimed in claim 1 or 2, it is characterized in that, described blood-snow willow extract, sticky people's grass extract, amethyst mushroom extract, Decaspermum gracilentum (Hance) Merr et Perry leaf extract, Cortex phoebes sheareri extract, its preparation method is: by blood-snow willow, sticky people's grass, amethyst mushroom, Decaspermum gracilentum (Hance) Merr et Perry leaf, after Cortex phoebes sheareri pretreatment, mixing, obtain mixing medicinal raw material, be placed in boiler, add the clear water relative to its weight 5 ~ 7 times, the temperature of 120 ~ 130 DEG C is adopted to decoct extraction 1 ~ 3 time, each extraction time is 40 ~ 50min, filter, merging filtrate, after being cooled to room temperature again, precipitation process is carried out with the ethanol that mass concentration is 85%, the supernatant obtained takes out, be concentrated into 35 ~ 45%, obtain.
5. a kind of care composition removing foot abnormal flavour as claimed in claim 1 or 2, it is characterized in that, described Radix embeliae laetae extract, Herba Chelidonii extract, its preparation method is: Radix embeliae laetae and Herba Chelidonii are dried, be placed in grinder grind into powder, obtain hybrid medicine powder, adding relative to the mass concentration of its weight 3 ~ 4 times in gained hybrid medicine powder is the ethanol of 52 ~ 55%, adopt ultrasonic frequency to be that 30 ~ 50Hz extracts 10 ~ 20min, filter, obtain solution and get final product.
6. a kind of care composition removing foot abnormal flavour as claimed in claim 1 or 2, it is characterized in that, described Folium Eucommiae ulmoidis extract, its preparation method is: cleaned by Folium Eucommiae ulmoidis after drying, be ground into coarse powder, take out, be cooled to room temperature, then be placed in baking oven 80 ~ 85 DEG C of bakings after 20 ~ 30 minutes, be placed in super micron mill and pulverize, cross 100 mesh sieves, obtain powder and get final product.
7. a kind of preparation method removing the care composition of foot abnormal flavour as described in any one of claim 1 ~ 6, is characterized in that, comprise the following steps:
(1) blood-snow willow extract is prepared, sticky people's grass extract, amethyst mushroom extract, Decaspermum gracilentum (Hance) Merr et Perry leaf extract and Cortex phoebes sheareri extract: by blood-snow willow, sticky people's grass, amethyst mushroom, Decaspermum gracilentum (Hance) Merr et Perry leaf, after Cortex phoebes sheareri pretreatment, mixing, obtain mixing medicinal raw material, be placed in boiler, add the clear water relative to its weight 5 ~ 7 times, the temperature of 120 ~ 130 DEG C is adopted to decoct extraction 1 ~ 3 time, each extraction time is 40 ~ 50min, filter, merging filtrate, after being cooled to room temperature again, precipitation process is carried out with the ethanol that mass concentration is 85%, the supernatant obtained takes out, be concentrated into 35 ~ 45%, obtain,
(2) Radix embeliae laetae extract and Herba Chelidonii extract is prepared: Radix embeliae laetae and Herba Chelidonii are dried, be placed in grinder grind into powder, obtain hybrid medicine powder, adding relative to the mass concentration of its weight 3 ~ 4 times in gained hybrid medicine powder is the ethanol of 52 ~ 55%, ultrasonic frequency is adopted to be that 30 ~ 50Hz extracts 10 ~ 20min, filter, obtain solution and get final product;
(3) prepare Folium Eucommiae ulmoidis extract: cleaned by Folium Eucommiae ulmoidis after drying, be ground into coarse powder, take out, be cooled to room temperature, then to be placed in baking oven 80 ~ 85 DEG C of bakings after 20 ~ 30 minutes, be placed in super micron mill and pulverize, cross 100 mesh sieves, obtain powder and get final product;
(4) raw material mixing: by potassium chloride, vitamin C, hibitane, cetylpyridinium chloride, L-Mentholum, glycerol, glucide, propylene glycol, Sodium Azulenesulfonate, hibitane, the mixing of L-Mentholum in dispensing canister, add the blood-snow willow extract obtained by above-mentioned steps (1) to (3), sticky people's grass extract, amethyst mushroom extract, Decaspermum gracilentum (Hance) Merr et Perry leaf extract, Cortex phoebes sheareri extract, Radix embeliae laetae extract, Herba Chelidonii extract, Folium Eucommiae ulmoidis extract again, stir, obtain raw mixture;
(5) above-mentioned steps (4) gained raw mixture is placed in ultrasound wave dispersing apparatus and carries out ultrasonic disperse process, the care composition removing foot abnormal flavour can be obtained.
8. a kind of preparation method removing the care composition of foot abnormal flavour as claimed in claim 7, it is characterized in that, the process conditions that described raw mixture ultrasound wave dispersing apparatus carries out ultrasonic disperse process are: first ultrasonic frequency is adjusted to 60 ~ 100Hz, process 30 ~ 50s, adjusting ultrasonic frequency is again 130 ~ 150Hz, process 10 ~ 20s.
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| CN103446343A (en) * | 2013-09-13 | 2013-12-18 | 吕培卖 | External pharmaceutical composition for treating dermatophytosis and foot ordor |
| CN104107373A (en) * | 2014-07-01 | 2014-10-22 | 王统述 | Traditional Chinese medicine for treating beriberi, foot odor and foot sweating |
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|---|---|---|---|---|
| CN103446343A (en) * | 2013-09-13 | 2013-12-18 | 吕培卖 | External pharmaceutical composition for treating dermatophytosis and foot ordor |
| CN104107373A (en) * | 2014-07-01 | 2014-10-22 | 王统述 | Traditional Chinese medicine for treating beriberi, foot odor and foot sweating |
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