CN105193842A - Effervescent tablets capable of supplementing antioxidant and application of effervescent tablets - Google Patents
Effervescent tablets capable of supplementing antioxidant and application of effervescent tablets Download PDFInfo
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- CN105193842A CN105193842A CN201510743718.4A CN201510743718A CN105193842A CN 105193842 A CN105193842 A CN 105193842A CN 201510743718 A CN201510743718 A CN 201510743718A CN 105193842 A CN105193842 A CN 105193842A
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- astaxanthin
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Abstract
The invention discloses effervescent tablets capable of supplementing an antioxidant. The raw materials of the effervescent tablets comprise components in parts by weight as follows: 1-10 parts of astaxanthin, 50-100 parts of sugar, 1-10 parts of potassium carbonate, 0.1-1.5 parts of calcium carbonate, 0.1-1.5 parts of magnesium sulfate, 1-10 parts of vitamin C, 1-10 parts of sodium chloride, 2-16 parts of sodium bicarbonate and 2-16 parts of citric acid. The electrolyte effervescent tablets can supplement the antioxidant timely during or after sports, can be applied to other carriers for preparation of preparations or solutions and can be added to health care products and food for supplementing energy. According to the specific characteristic that the effervescent tablets are ionized under the action of water to generate a large amount of carbon dioxide, the tablets are disintegrated and melted rapidly, the astaxanthin can be dispersed in the solution rapidly and uniformly, a uniformly mixed solution can be formed, absorption by a human body is better facilitated, and the effect is taken quickly. Fatigue recovery after sports can be improved remarkably, inflammation can be reduced remarkably, and physical strength is recovered quickly.
Description
Technical field
The present invention relates to medicine, health-related technical field of pharmaceuticals, particularly relate to material and the application thereof of antioxidant drug.
Background technology
Human body is in normal life oxidation activity, and organic compound incomplete oxidation will produce free radical.Under normal condition, human body antioxidant system meeting scavenging free radicals, maintains organism balance.But at vigorous exercise, during the mental activity of high concentration, because body runs up, power consumption is large, and the energy supply material of metabolism consumes a large amount of oxygen at short notice, and free radical can be caused to roll up.
The oxygen consumption activity having research to confirm to exceed usual 70% can produce the free radical of 12 times, human body antioxidant system cannot remove the free radical because highly energy-consuming height oxygen consumption state produces in a large number in time, highly active free radical can capture the electronics of cell, cause cell, mitochondrion, DNA, hyaluronic destruction, causes muscle tendon fatigue of joint and aches and inflammation.Therefore supplement antioxidant and can alleviate the hyaluronic destruction of radical pair cell mitochondrial DNA, to play allaying tiredness, prevention is ached and inflammation.
Astaxanthin (astaxanthin), has another name called astaxanthin, Astaxanthin, astaxanthin chemical name: 3,3 '-dihydroxy-4,4 '-diketo beta-carotene, pigment Aj067-69CASNo:472-61-7, molecular formula C40H52O4, molecular weight is 596.86.
Astaxanthin is a Carotenoids, and be also the highest level product of carotenogenesis, in rediance, chemical constitution is similar to beta-carotene.And beta-carotene, phylloxanthin, canthaxanthin, lycopene etc. are all the intermediate products of carotenogenesis, therefore at nature, astaxanthin has the strongest non-oxidizability.Extensively be present in biosphere, in the feather of particularly shrimp, Eriocheir sinensis, fish, frond, yeast and birds, content is higher, and be one of carotenoid main in marine organism, it has following characteristic.
Superpower non-oxidizability: astaxanthin is a kind of chain interruption type antioxidant, be current most powerful antioxidant, its oxidation resistance is 1000 times of vitamin E, 10 times of lycopene.It has the most comprehensively " high anti-oxidation " effect, and antioxidation process is very complete.Unlike antioxidant as β mono-carotene, lycopene, cryptoxanthin etc., be only simply neutralized the free radical in body.These " after neutralization molecules " will stop always and pile up in vivo, lack perfect process, become on the contrary " pro-oxidant ", McNulty adopts x line diffraction analysis also to prove, β mono-carotene and lycopene are by the phospholipid bilayer upsetting cell membrane, there is enzymatic oxidation effect on the contrary, astaxanthin then can good stabilizing cell membrane, present powerful anti-oxidation characteristics, natural astaxanthin then can be attached on free matrix, stop the raw chain reaction of destruction of free radical forevermore, and itself can not become pro-oxidant.
Extremely strong penetration power: astaxanthin can penetrate blood brain barrier, blood pancreas barrier, this three large mankind's main barrier of blood-testis barrier, and being the carotenoid that uniquely can penetrate blood brain barrier, is therefore possible act on brain cell and the unique Carotenoids of eyeball retina.
Cross-film stability: biological cell film is made up of phospholipid bilayer, natural astaxanthin (supper vitamin E) can cross over the phospholipid bilayer of cell membrane, prevent the oxidized infringement of phospholipid molecule, well ensure the stability of cell membrane, thus the life-span of significant prolongation cell.
Superabsorbent: because astaxanthin molecular weight is little---596.8 dalton, even if add that the ester group at two ends is also less than 1000 dalton, is very easily absorbed by the body, namely can arrive each organ of human body in 20 minutes.
Therefore before motion, supplement the oxidation resistance that astaxanthin can strengthen human body in motion and after motion, allaying tiredness prevention is ached and inflammation.
Astaxanthin is liposoluble substance, makes soft capsule at present more.Exist and reach assigned address not rapidly, drug effect plays the delayed problem of timeliness.
In motion, electrolyte metabolism is very strong, and electrolyte runs off in a large number with perspiration.Electrolyte ingredient is mainly sodium K-Mg-Ca and other trace element.Hyponatremia and muscle spasm can be caused during human body sodium deficiency.Potassium deficiency can affect amount of insulin secretion, and to cause sugar to utilize limited, and muscle blood flow amount reduces and causes muscle weakness cardiac disorder.Magnesium deficiency can affect sodium Potassium Metabolism makes myocardial cell potassium deficiency, and cause arrhythmia, motor capacity declines to a great extent.Simple moisturizing can further exacerbate water salt metabolism unbalance, and therefore during moisturizing, suitable electrolyte supplement is conducive to the balance maintaining body fluid, maintains normal motor capacity.
Summary of the invention
The present invention is directed to above situation and propose a kind of water dispersible microscapsule powder using astaxanthin to make after embedding, and using effervescent tablet that powder particle is made as adding ingredient, this form fully in aqueous solution, absorption of human body can be beneficial to by dispersing and dissolving.
The effervescent tablet of a kind of supplementary antioxidant involved in the present invention, effervescent tablet raw material, according to weight score, comprises following composition: astaxanthin 1 ~ 10 part; Sugar 50 ~ 100 parts; Potassium carbonate 1 ~ 10 part; Calcium carbonate 0.1 ~ 1.5 part; 0.1 ~ 1.5 part, magnesium sulfate; Vitamin C 1 ~ 10 part; 1 ~ 10 part, sodium chloride; Sodium bicarbonate 2 ~ 16 parts; Citric acid 2 ~ 16 parts.
Say further: this effervescent tablet raw material, according to weight score, comprises following composition: astaxanthin 1 ~ 8 part; Sugar 50 ~ 80 parts; Potassium carbonate 1 ~ 8 part; Calcium carbonate 0.1 ~ 1.5 part; 0.1 ~ 1.5 part, magnesium sulfate; Vitamin C 1 ~ 8 part; 1 ~ 10 part, sodium chloride; Sodium bicarbonate 4 ~ 16 parts; Citric acid 4 ~ 16 parts.
Further illustrate: the score by weight of effervescent tablet raw material, comprises following component: astaxanthin 1 ~ 6 part; Sugar 50 ~ 70 parts; Potassium carbonate 2 ~ 6 parts; Calcium carbonate 0.1 ~ 1 part; 0.1 ~ 1 part, magnesium sulfate; Vitamin C 1 ~ 6 part; 2 ~ 10 parts, sodium chloride; Sodium bicarbonate 6 ~ 16 parts; Citric acid 6 ~ 16 parts.
Further illustrate: the score by weight of effervescent tablet raw material, comprises following component: astaxanthin 1 ~ 2 part; Sugar part 50 ~ 60 parts; Potassium carbonate 3 ~ 4 parts; Calcium carbonate 0.1 ~ 1 part; 0.1 ~ 1 part, magnesium sulfate; Vitamin C 1 ~ 2 part; 3 ~ 8 parts, sodium chloride; Sodium bicarbonate 8 ~ 14 parts; Citric acid 8 ~ 14 parts.
Further illustrate: the score by weight of effervescent tablet raw material, comprises following component:
Astaxanthin 2 parts;
Sugar 56 parts;
Potassium carbonate 3.6 parts;
Calcium carbonate 0.8 part;
0.6 part, magnesium sulfate;
Catergen part;
4 parts, sodium chloride;
Sodium bicarbonate 12 parts;
Citric acid 10 parts.
Above-mentioned sugar comprises anhydrous glucose, Oligomeric maltose, fructose.
The effervescent tablet of a kind of supplementary antioxidant involved in the present invention can add medical science or bromatology or the upper receptible carrier of health product snow and make the preparation being applied to and supplementing antioxidant in motion after motion in time.
The present invention also discloses a kind of for supplementing antioxidant and electrolytical effervescent tablet after motion in moving in time for the preparation of the medicine mending enough energy to body, for the health product to body makeup energy, for the application in the food to body makeup energy.
The invention discloses after one can move at the volley, supplement the electrolyte effervescent tablets of antioxidant in time, this effervescent tablet can also be applied to other carriers and make preparation or solution, and in the health product that can add makeup energy to and food.Ionize under the effect of water by effervescent tablet is distinctive, produce a large amount of carbon dioxide, make the rapid disintegrate of tablet and thawing, astaxanthin can be allowed to disperse rapidly in the solution uniform, form the solution of mix homogeneously, advantageously in absorption of human body, realize the object of rapid-onset.Significantly can improve post exercise fatigue recovery and reduce inflammation and occur, regain one's strength rapidly.
[detailed description of the invention]
To be described in further detail the present invention according to detailed description of the invention below.
Embodiment 1: this effervescent tablet raw material comprises following component by weight: astaxanthin 1 part, sugar 56 parts, potassium carbonate 3.6 parts, calcium carbonate 0.8 part, 0.6 part, magnesium sulfate, vitamin C 1 part, 4 parts, sodium chloride, sodium bicarbonate 12 parts, citric acid 10 parts.
Embodiment 2: this effervescent tablet raw material comprises following component by weight: astaxanthin 2 parts, sugar 56 parts, potassium carbonate 3.6 parts, calcium carbonate 0.8 part, 0.6 part, magnesium sulfate, Catergen part, 4 parts, sodium chloride, sodium bicarbonate 12 parts, citric acid 12 parts.
Embodiment 3: this effervescent tablet raw material comprises following component by weight: astaxanthin 3 parts, sugar 60 parts, potassium carbonate 3.6 parts, calcium carbonate 0.8 part, 0.6 part, magnesium sulfate, vitamin C 3 parts, 4 parts, sodium chloride, sodium bicarbonate 12 parts, citric acid 14 parts.
Embodiment 4: this effervescent tablet raw material comprises following component by weight: astaxanthin 4 parts, sugar 60 parts, potassium carbonate 3.6 parts, calcium carbonate 0.8 part, 0.6 part, magnesium sulfate, vitamin C 3 parts, 4 parts, sodium chloride, sodium bicarbonate 12 parts, citric acid 14 parts.
Embodiment 5: this effervescent tablet raw material comprises following component by weight: astaxanthin 5 parts, sugar 80 parts, potassium carbonate 3.6 parts, calcium carbonate 0.8 part, 0.6 part, magnesium sulfate, vitamin C 3 parts, 4 parts, sodium chloride, sodium bicarbonate 12 parts, citric acid 12 parts.
The invention discloses after one can move at the volley, supplement the effervescent tablet of antioxidant in time, this effervescent tablet can also be applied to other carriers and make preparation or solution, and in the health product that can add makeup energy to and food.Ionize under the effect of water by effervescent tablet is distinctive, produce a large amount of carbon dioxide, make the rapid disintegrate of tablet and thawing, astaxanthin can be allowed to disperse rapidly in the solution uniform, form the solution of mix homogeneously, advantageously in absorption of human body, realize the object of rapid-onset.Significantly can improve post exercise fatigue recovery and reduce inflammation and occur, regain one's strength rapidly.
Of the present invention for supplementing antioxidant and electrolytical effervescent tablet between moving period to the sportive recovery from fatigue effect of sport people for checking, carry out following experiment:
1, subject material: with embodiment one for laboratory sample, with heat G/Ws such as equal-volumes for control sample;
2, study subject: choose pulse close, nearly 5 kilometers to run achievements, in the recent period training plan, moon race amount and nearest 30 kilometers of achievements be that conditional filtering goes out to run friendly 40 people and participates in the experiment.Be divided into experimental group and matched group at random, often organize 20 people.Experiment the last fortnight starts to take a made aqueous solution 500ml of laboratory sample, until experiment terminates.Study subject maintains full diet, does not take other nutritional supplements;
3, experimental technique: with certain marathon for formally to test day, experimental subject need be run through to create personal best record for target as possible, as discomfort in way, can abandon.Collect rich and next day in morning after wakeing up early morning on the same day, morning on the 3rd wins data.Data variation was won to judge fatigue recovery degree morning on the same day relative to match with next day and three days data.
Recovery extent criterion:
Recovering completely to win morning won in 5 times relative to match morning on the same day;
It is rich relative to winning in 10 times morning on the same day of competing that part recovers morning;
Do not recover to win morning and won more than 10 times morning on the same day relative to match.
4, experimental result:
Result can be found out:
Experimental group complete recovery rate next day is recover completely for the 60%, three day 100%;
Matched group complete recovery rate next day is recover completely for the 25%, three day 75%.
Other formula of compositions of the present invention can reach good resisting fatigue effect equally.Above-mentioned experiment shows, compositions of the present invention is suitable for the fatigue recovery between moving period very much, ensure that persistency and the endurance of motion, to raising sports achievement, has facilitation.
The above, it is only present pre-ferred embodiments, not any pro forma restriction is done to the present invention, although the present invention discloses as above with preferred embodiment, but and be not used to limit the present invention, any those skilled in the art, do not departing within the scope of technical solution of the present invention, make a little change when the technology contents of above-mentioned announcement can be utilized or be modified to the Equivalent embodiments of equivalent variations, in every case be do not depart from technical solution of the present invention content, any simple modification that above embodiment is done is referred to according to the technology of the present invention, equivalent variations and modification, all belong in the scope of technical solution of the present invention.
Claims (8)
1. an effervescent tablet for supplementary antioxidant, is characterized in that, this effervescent tablet raw material, according to weight score, comprises following composition: astaxanthin 1 ~ 10 part; Sugar 50 ~ 100 parts; Potassium carbonate 1 ~ 10 part; Calcium carbonate 0.1 ~ 1.5 part; 0.1 ~ 1.5 part, magnesium sulfate; Vitamin C 1 ~ 10 part; 1 ~ 10 part, sodium chloride; Sodium bicarbonate 2 ~ 16 parts; Citric acid 2 ~ 16 parts.
2. supplement the effervescent tablet of antioxidant according to claim 1, it is characterized in that, this effervescent tablet raw material, according to weight score, comprises following composition: astaxanthin 1 ~ 8 part; Sugar 50 ~ 80 parts; Potassium carbonate 1 ~ 8 part; Calcium carbonate 0.1 ~ 1.5 part; 0.1 ~ 1.5 part, magnesium sulfate; Vitamin C 1 ~ 8 part; 1 ~ 10 part, sodium chloride; Sodium bicarbonate 4 ~ 16 parts; Citric acid 4 ~ 16 parts.
3. supplement the effervescent tablet of antioxidant according to claim 1, it is characterized in that, the score by weight of effervescent tablet raw material, comprises following component: astaxanthin 1 ~ 6 part; Sugar 50 ~ 70 parts; Potassium carbonate 2 ~ 6 parts; Calcium carbonate 0.1 ~ 1 part; 0.1 ~ 1 part, magnesium sulfate; Vitamin C 1 ~ 6 part; 2 ~ 10 parts, sodium chloride; Sodium bicarbonate 6 ~ 16 parts; Citric acid 6 ~ 16 parts.
4. supplement the effervescent tablet of antioxidant according to claim 1, it is characterized in that, the score by weight of effervescent tablet raw material, comprises following component: astaxanthin 1 ~ 2 part; Sugar part 50 ~ 60 parts; Potassium carbonate 3 ~ 4 parts; Calcium carbonate 0.1 ~ 1 part; 0.1 ~ 1 part, magnesium sulfate; Vitamin C 1 ~ 2 part; 3 ~ 8 parts, sodium chloride; Sodium bicarbonate 8 ~ 14 parts; Citric acid 8 ~ 14 parts.
5. supplement the effervescent tablet of antioxidant according to claim 1, it is characterized in that, the score by weight of effervescent tablet raw material, comprises following component:
Astaxanthin 2 parts;
Sugar 56 parts;
Potassium carbonate 3.6 parts;
Calcium carbonate 0.8 part;
0.6 part, magnesium sulfate;
Catergen part;
4 parts, sodium chloride;
Sodium bicarbonate 12 parts;
Citric acid 10 parts.
6. according to claim 1-5, supplement the effervescent tablet of antioxidant, it is characterized in that, above-mentioned sugar comprises anhydrous glucose, Oligomeric maltose, fructose.
7. supplement the application of the effervescent tablet of antioxidant according to claim 6, it is characterized in that, for supplementing antioxidant and electrolyte in time, this effervescent tablet can add medical science or bromatology or the upper receptible carrier of health product snow and make preparation.
8. supplement the application of the effervescent tablet of antioxidant according to claim 6, it is characterized in that, for supplementing antioxidant and electrolyte in time after motion in motion, the medicine into body benefit enough energy can be applied to, to the health product of body makeup energy, in the food to body makeup energy.
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| CN201510743718.4A CN105193842A (en) | 2015-11-05 | 2015-11-05 | Effervescent tablets capable of supplementing antioxidant and application of effervescent tablets |
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| CN201510743718.4A CN105193842A (en) | 2015-11-05 | 2015-11-05 | Effervescent tablets capable of supplementing antioxidant and application of effervescent tablets |
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017206026A1 (en) * | 2016-05-30 | 2017-12-07 | 阿士力(深圳)运动健康科技有限公司 | Energy composition for enhancing athletic ability |
| CN107802643A (en) * | 2017-12-12 | 2018-03-16 | 江苏扬新生物医药有限公司 | A kind of soft capsule containing astaxanthin |
| CN108308493A (en) * | 2018-01-25 | 2018-07-24 | 江苏神华药业有限公司 | A kind of anti-fatigue solid beverage and preparation method of astaxanthin-containing |
| CN109007521A (en) * | 2018-10-16 | 2018-12-18 | 云南爱尔康生物技术有限公司 | A kind of Astaxanthin In Haematococcus Pluvialis effervescent tablet and preparation method thereof |
| CN109527325A (en) * | 2018-11-20 | 2019-03-29 | 江苏汉典生物科技股份有限公司 | A kind of sports type effervescent tablet and preparation method thereof |
| CN110876440A (en) * | 2019-11-26 | 2020-03-13 | 睿藻生物科技（苏州）有限公司 | Astaxanthin effervescent tablet for improving athletic ability and preparation method thereof |
| CN110881604A (en) * | 2019-12-07 | 2020-03-17 | 安徽克菱保健科技有限公司 | Vc effervescent tablet |
| CN112890067A (en) * | 2021-03-14 | 2021-06-04 | 云南爱尔康生物技术有限公司 | Colorful effervescent bead containing haematococcus pluvialis-derived astaxanthin and preparation method thereof |
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Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017206026A1 (en) * | 2016-05-30 | 2017-12-07 | 阿士力(深圳)运动健康科技有限公司 | Energy composition for enhancing athletic ability |
| CN109475513A (en) * | 2016-05-30 | 2019-03-15 | 阿士力(深圳)运动健康科技有限公司 | The energy composition of lifting motion ability |
| CN107802643A (en) * | 2017-12-12 | 2018-03-16 | 江苏扬新生物医药有限公司 | A kind of soft capsule containing astaxanthin |
| CN107802643B (en) * | 2017-12-12 | 2020-03-27 | 江苏扬新生物医药有限公司 | Soft capsule containing astaxanthin |
| CN108308493A (en) * | 2018-01-25 | 2018-07-24 | 江苏神华药业有限公司 | A kind of anti-fatigue solid beverage and preparation method of astaxanthin-containing |
| CN109007521A (en) * | 2018-10-16 | 2018-12-18 | 云南爱尔康生物技术有限公司 | A kind of Astaxanthin In Haematococcus Pluvialis effervescent tablet and preparation method thereof |
| CN109527325A (en) * | 2018-11-20 | 2019-03-29 | 江苏汉典生物科技股份有限公司 | A kind of sports type effervescent tablet and preparation method thereof |
| CN110876440A (en) * | 2019-11-26 | 2020-03-13 | 睿藻生物科技（苏州）有限公司 | Astaxanthin effervescent tablet for improving athletic ability and preparation method thereof |
| CN110881604A (en) * | 2019-12-07 | 2020-03-17 | 安徽克菱保健科技有限公司 | Vc effervescent tablet |
| CN112890067A (en) * | 2021-03-14 | 2021-06-04 | 云南爱尔康生物技术有限公司 | Colorful effervescent bead containing haematococcus pluvialis-derived astaxanthin and preparation method thereof |
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