CN105126717A - Chitosan-coated vitamin C micro-capsule and preparing method thereof - Google Patents
Chitosan-coated vitamin C micro-capsule and preparing method thereof Download PDFInfo
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- CN105126717A CN105126717A CN201510558492.0A CN201510558492A CN105126717A CN 105126717 A CN105126717 A CN 105126717A CN 201510558492 A CN201510558492 A CN 201510558492A CN 105126717 A CN105126717 A CN 105126717A
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Abstract
The invention discloses a chitosan-coated vitamin C micro-capsule. The chitosan-coated vitamin C micro-capsule is prepared from, by mass, 0.4-2.5 parts of vitamin C, 0.02-0.04 part of anhydrous magnesium sulfate, 15.5-27.0 parts of soybean oil, 0.4-0.6 part of Span 80, 0.6-1.2 parts of glacial acetic acid, 0.6-1.0 part of chitosan, 1.6-2.9 parts of polysorbate 80, 0.4-0.6 part of curing agents and the balance deionized water. The invention further provides a preparing method for the chitosan-coated vitamin C micro-capsule. The chitosan-coated vitamin C micro-capsule prepared by adopting a multiphase emulsion method is of a regular spherical multi-core structure, and the coverage rate of vitamin C can be 20-50%. The prepared vitamin C micro-capsule effectively prevents the vitamin C from being oxidized, and has good biocompatibility and degradability.
Description
Technical field
The invention belongs to chemical field, relate to a kind of vitamin C microcapsule, specifically a kind of Chitosan-coated vitamin C microcapsule and preparation method thereof.
Background technology
Vitamin C is widely used in the numerous areas such as medicine, food, cosmetics as a kind of natural antioxidant.But vitamin C can be subject to the ambient influnences such as high temperature, pH, moisture, light and air and decompose rotten, limits ascorbic action effect and range of application.Utilize microcapsules technology to carry out embedding to vitamin C and can not only improve the stability of vitamin C to environment, and vitamin C can be made to carry out slowly-releasing.The main preparation method of current vitamin C capsule has spray drying process, sugared vitrification, oil phase phase separation method, interfacial polymerization, drying with water bath method and yeast microcapsule method.Multiphase emulsion method has that method is easy, reaction condition is gentle and the advantage such as equipment is simple and enjoy favor.Be that the microcapsules of wall material have good biocompatibility, stability, controlled capability and antibiotic property with Chitosan-phospholipid complex, and wide material sources are with low cost.Multiphase emulsion method is utilized to be that wall material carries out coated to vitamin C with shitosan; can exempt from be affected by the external environment and go bad by available protecting vitamin C; there is the advantages such as clad ratio is high, good stability; and preparation is simple, every field can be applied to as antiseptic and antioxidant.Current is that wall material is not yet reported by the correlative study of multiphase emulsion legal system for vitamin C capsule with shitosan.
Summary of the invention
For above-mentioned technical problem of the prior art, the invention provides a kind of Chitosan-coated vitamin C microcapsule and preparation method thereof, it is not high that described this Chitosan-coated vitamin C microcapsule and preparation method thereof solves vitamin C microcapsule clad ratio of the prior art, the technical problem that stability is not good.
The invention provides a kind of Chitosan-coated vitamin C microcapsule, the parts by weight of each raw material are as follows:
Vitamin C 0.4-2.5 part,
Anhydrous magnesium sulfate 0.02-0.04 part,
Soybean oil 15.5-27.0 part,
Sorbester p17 0.4-0.6 part,
Glacial acetic acid 0.6-1.2 part,
Shitosan 0.6-1.0 part,
Tween 80 1.6-2.9 part,
Curing agent 0.4-0.6 part,
Surplus is deionized water.
Further, described curing agent is sodium phosphate trimer, calcium chloride or sodium alginate.
Present invention also offers the preparation method of above-mentioned a kind of Chitosan-coated vitamin C microcapsule, comprise the following steps:
(1) 0.4-2.5 part vitamin C is dissolved in 3.16-10.88 part deionized water, after adding 0.02-0.04 part anhydrous magnesium sulfate, ultrasonic complete soluble in water rear for subsequent use to vitamin C;
(2) vitamin C aqueous solution step (1) obtained, 15.5-27.0 part soybean oil and 0.4-0.6 part sorbester p17 are placed in a reaction vessel, and after 300-500r/min mechanical agitation 1-2h, homogeneous 4-6 minute obtains interior phase Water-In-Oil solution;
(3) be dissolved in by 0.6-1.0 part shitosan after in aqueous acetic acid for subsequent use, described aqueous acetic acid is mixed with 53.28-67.72 part water by 0.6-1.2 part glacial acetic acid;
(4) the shitosan aqueous acetic acid that step (3) obtains is poured in the reaction vessel in step (2), add 1.6-2.9 part Tween 80, after 300-500r/min mechanical agitation 10-30min, add 0.4-0.6 part curing agent, 300-500r/min mechanical agitation 10-30min;
(5) solution centrifugal in step (4) be separated and wash by absolute ethyl alcohol and deionized water respectively, after vacuum freeze drying, obtaining Chitosan-coated vitamin C microcapsule.
Chitosan-coated vitamin C microcapsule of the present invention utilizes multiphase emulsion method that vitamin C is uniformly dispersed, interior phase water-in-oil emulsion drop not only completely cuts off air and stops vitamin C to external diffusion, the Chitosan-coated vitamin C microcapsule of above-mentioned gained is regular spherical coenocytism, vitamin C clad ratio can reach 20-50%, effectively prevent ascorbic autoxidation.
Owing to adopting, to have good filming and rich surface containing amino shitosan be wall material, by the electrostatical binding between curing agent, chitosan film solidified thus strengthen shitosan shell stability.In addition, the microcapsule method adopting multiphase emulsion legal system standby is easy, reaction condition is gentle, equipment is simple; Shitosan wall material has good biocompatibility, stability, controlled capability and antibiotic property, and the advantage that wide material sources are with low cost.Therefore the vitamin C microcapsule prepared of the present invention not only simple process, wide material sources are with low cost but also have good biocompatibility, stability, anti-oxidant and fungistatic effect, have a good application prospect.
The present invention compares with prior art, and its technological progress is significant.Vitamin C microcapsule prepared by the present invention effectively prevent ascorbic oxidation, has good biocompatibility and degradability.
Accompanying drawing explanation
Fig. 1 is the electron microscope picture of Chitosan-coated vitamin C microcapsule of the present invention.
detailed description of the invention:
Also by reference to the accompanying drawings the present invention is described in further detail below by embodiment, but do not limit the present invention.
embodiment 1
A kind of Chitosan-coated vitamin C microcapsule, the parts by weight of each raw material are as follows:
Vitamin C 0.4 part
Anhydrous magnesium sulfate 0.02 part
Soybean oil 15.5 parts
Sorbester p17 0.4 part
0.6 part, glacial acetic acid
Shitosan 0.6 part
Tween 80 1.6 parts
Sodium phosphate trimer 0.4 part
Surplus is deionized water.
The preparation method of above-mentioned Chitosan-coated vitamin C microcapsule comprises the following steps:
1) 0.4 part of vitamin C is dissolved in 3.16 parts of deionized waters, after adding 0.02 part of anhydrous magnesium sulfate, ultrasonic complete soluble in water rear for subsequent use to vitamin C.
2) vitamin C aqueous solution step (1) obtained, 15.5 portions of soybean oils and 0.4 part of sorbester p17 are placed in 100mL there-necked flask, and after 300r/min mechanical agitation 1h, homogeneous obtains interior phase Water-In-Oil solution for 4 minutes
3) 0.6 part of shitosan is dissolved in aqueous acetic acid (0.6 part of glacial acetic acid mixes with 77.32 parts of water) for subsequent use afterwards.
4) the shitosan aqueous acetic acid that step (3) obtains is poured in the there-necked flask in step (2), add 1.6 parts of Tween 80s, after 300r/min mechanical agitation 10min, add 0.4 part of sodium phosphate trimer, 300r/min mechanical agitation 10min.
5) solution centrifugal in step (4) be separated and wash by absolute ethyl alcohol and deionized water respectively, after vacuum freeze drying 48h, obtaining Chitosan-coated vitamin C microcapsule.
Measure through thermogravimetric analyzer Q5000, in the vitamin C microcapsule of gained, vitamin C clad ratio is 20.5%.
embodiment 2
A kind of Chitosan-coated vitamin C microcapsule, the parts by weight of each raw material are as follows:
Catergen .5 part
Anhydrous magnesium sulfate 0.04 part
Soybean oil 27.0 parts
Sorbester p17 0.6 part
1.2 parts, glacial acetic acid
Shitosan 1.0 parts
Tween 80 2.9 parts
Sodium alginate 0.6 part
Surplus is deionized water.
The preparation method of above-mentioned Chitosan-coated vitamin C microcapsule comprises the following steps:
1) 2.5 parts of vitamin Cs are dissolved in 10.88 parts of deionized waters, after adding 0.04 part of anhydrous magnesium sulfate, ultrasonic complete soluble in water rear for subsequent use to vitamin C.
2) vitamin C aqueous solution step (1) obtained, 27.0 portions of soybean oils and 0.6 part of sorbester p17 are placed in 100mL there-necked flask, and after 500r/min mechanical agitation 2h, homogeneous obtains interior phase Water-In-Oil solution for 6 minutes
3) 1.0 parts of shitosans are dissolved in aqueous acetic acid (1.2 parts of glacial acetic acid mix with 53.28 parts of water) for subsequent use afterwards.
4) the shitosan aqueous acetic acid that step (3) obtains is poured in the there-necked flask in step (2), add 2.9 parts of Tween 80s, after 500r/min mechanical agitation 30min, add 0.6 part of sodium alginate, 500r/min mechanical agitation 30min.
5) solution centrifugal in step (4) be separated and wash by absolute ethyl alcohol and deionized water respectively, after vacuum freeze drying 48h, obtaining Chitosan-coated vitamin C microcapsule.
Measure through thermogravimetric analyzer Q5000, in the vitamin C microcapsule of gained, vitamin C clad ratio is 38.6%.
embodiment 3
A kind of Chitosan-coated vitamin C microcapsule, the parts by weight of each raw material are as follows:
Vitamin C 0.7 part
Anhydrous magnesium sulfate 0.03 part
Soybean oil 22.0 parts
Sorbester p17 0.5 part
0.8 part, glacial acetic acid
Shitosan 0.8 part
Tween 80 1.8 parts
0.5 part, calcium chloride
Surplus is deionized water.
The preparation method of above-mentioned Chitosan-coated vitamin C microcapsule comprises the following steps:
1) 0.7 part of vitamin C is dissolved in 10.32 parts of deionized waters, after adding 0.03 part of anhydrous magnesium sulfate, ultrasonic complete soluble in water rear for subsequent use to vitamin C.
2) vitamin C aqueous solution step (1) obtained, 22.0 portions of soybean oils and 0.5 part of sorbester p17 are placed in 100mL there-necked flask, and after 400r/min mechanical agitation 1.5h, homogeneous obtains interior phase Water-In-Oil solution for 5 minutes.
3) 0.8 part of shitosan is dissolved in aqueous acetic acid (0.8 part of glacial acetic acid mixes with 62.28 parts of water) for subsequent use afterwards.
4) the shitosan aqueous acetic acid that step (3) obtains is poured in the there-necked flask in step (2), add 1.8 parts of Tween 80s, after 400r/min mechanical agitation 20min, add 0.5 part of calcium chloride, 400r/min mechanical agitation 20min.
5) solution centrifugal in step (4) be separated and wash by absolute ethyl alcohol and deionized water respectively, after vacuum freeze drying 48h, obtaining Chitosan-coated vitamin C microcapsule.
Measure through thermogravimetric analyzer Q5000, in the vitamin C microcapsule of gained, vitamin C clad ratio is 26.5%.
embodiment 4
A kind of Chitosan-coated vitamin C microcapsule, the parts by weight of each raw material are as follows:
Vitamin C 1.6 parts
Anhydrous magnesium sulfate 0.04 part
Soybean oil 24.0 parts
Sorbester p17 0.5 part
1.0 parts, glacial acetic acid
Shitosan 0.7 part
Tween 80 2.2 parts
Sodium alginate 0.5 part
Surplus is deionized water.
The preparation method of above-mentioned Chitosan-coated vitamin C microcapsule comprises the following steps:
1) 1.6 parts of vitamin Cs are dissolved in 6.26 parts of deionized waters, after adding 0.04 part of anhydrous magnesium sulfate, ultrasonic complete soluble in water rear for subsequent use to vitamin C.
2) vitamin C aqueous solution step (1) obtained, 24.0 portions of soybean oils and 0.5 part of sorbester p17 are placed in 100mL there-necked flask, and after 500r/min mechanical agitation 2h, homogeneous obtains interior phase Water-In-Oil solution for 6 minutes
3) 0.7 part of shitosan is dissolved in aqueous acetic acid (1.0 parts of glacial acetic acid mix with 63.2 parts of water) for subsequent use afterwards.
4) the shitosan aqueous acetic acid that step (3) obtains is poured in the there-necked flask in step (2), add 2.2 parts of Tween 80s, after 500r/min mechanical agitation 30min, add 0.5 part of sodium alginate, 500r/min mechanical agitation 30min.
5) solution centrifugal in step (4) be separated and wash by absolute ethyl alcohol and deionized water respectively, after vacuum freeze drying 48h, obtaining Chitosan-coated vitamin C microcapsule.
Measure through thermogravimetric analyzer Q5000, in the vitamin C microcapsule of gained, vitamin C clad ratio is 38.9%.
embodiment 5
A kind of Chitosan-coated vitamin C microcapsule, the parts by weight of each raw material are as follows:
Vitamin C 1.8 parts
Anhydrous magnesium sulfate 0.03 part
Soybean oil 18.5 parts
Sorbester p17 0.4 part
0.8 part, glacial acetic acid
Shitosan 0.8 part
Tween 80 2.0 parts
0.6 part, calcium chloride
Surplus is deionized water.
The preparation method of above-mentioned Chitosan-coated vitamin C microcapsule comprises the following steps:
1) 1.8 parts of vitamin Cs are dissolved in 5.26 parts of deionized waters, after adding 0.03 part of anhydrous magnesium sulfate, ultrasonic complete soluble in water rear for subsequent use to vitamin C.
2) vitamin C aqueous solution step (1) obtained, 18.5 portions of soybean oils and 0.4 part of sorbester p17 are placed in 100mL there-necked flask, and after 500r/min mechanical agitation 1h, homogeneous obtains interior phase Water-In-Oil solution for 6 minutes
3) 0.8 part of shitosan is dissolved in aqueous acetic acid (0.8 part of glacial acetic acid mixes with 69.81 parts of water) for subsequent use afterwards.
4) the shitosan aqueous acetic acid that step (3) obtains is poured in the there-necked flask in step (2), add 2.0 parts of Tween 80s, after 500r/min mechanical agitation 20min, add 0.6 part of calcium chloride, 500r/min mechanical agitation 20min.
5) solution centrifugal in step (4) be separated and wash by absolute ethyl alcohol and deionized water respectively, after vacuum freeze drying 48h, obtaining Chitosan-coated vitamin C microcapsule.
Measure through thermogravimetric analyzer Q5000, in the vitamin C microcapsule of gained, vitamin C envelop rate is 49.1%.
Above said content be only the present invention conceive under basic explanation, and according to any equivalent transformation that technical scheme of the present invention is done, all should protection scope of the present invention be belonged to.
Claims (3)
1. a Chitosan-coated vitamin C microcapsule, is characterized in that the parts by weight of each raw material are as follows:
Vitamin C 0.4-2.5 part,
Anhydrous magnesium sulfate 0.02-0.04 part,
Soybean oil 15.5-27.0 part,
Sorbester p17 0.4-0.6 part,
Glacial acetic acid 0.6-1.2 part,
Shitosan 0.6-1.0 part,
Tween 80 1.6-2.9 part,
Curing agent 0.4-0.6 part,
Surplus is deionized water.
2. a kind of Chitosan-coated vitamin C microcapsule according to claim 1, is characterized in that: described curing agent is sodium phosphate trimer, calcium chloride or sodium alginate.
3. right 1 requires the preparation method of described a kind of Chitosan-coated vitamin C microcapsule, it is characterized in that comprising the following steps:
(1) 0.4-2.5 part vitamin C is dissolved in 3.16-10.88 part deionized water, after adding 0.02-0.04 part anhydrous magnesium sulfate, ultrasonic complete soluble in water rear for subsequent use to vitamin C;
(2) vitamin C aqueous solution step (1) obtained, 15.5-27.0 part soybean oil and 0.4-0.6 part sorbester p17 are placed in a reaction vessel, and after 300-500r/min mechanical agitation 1-2h, homogeneous 4-6 minute obtains interior phase Water-In-Oil solution;
(3) be dissolved in by 0.6-1.0 part shitosan after in aqueous acetic acid for subsequent use, described aqueous acetic acid is mixed with 53.28-67.72 part water by 0.6-1.2 part glacial acetic acid;
(4) the shitosan aqueous acetic acid that step (3) obtains is poured in the reaction vessel in step (2), add 1.6-2.9 part Tween 80, after 300-500r/min mechanical agitation 10-30min, add 0.4-0.6 part curing agent, 300-500r/min mechanical agitation 10-30min;
(5) solution centrifugal in step (4) be separated and wash by absolute ethyl alcohol and deionized water respectively, after vacuum freeze drying, obtaining Chitosan-coated vitamin C microcapsule.
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106580728A (en) * | 2017-01-17 | 2017-04-26 | 上海应用技术大学 | Vitamin C microcapsule and preparation method thereof |
| CN107384326A (en) * | 2017-07-25 | 2017-11-24 | 延安大学 | Gelatin chitosan nano silicon multinuclear microcapsules of storing energy through phase change preparation method |
| CN107699558A (en) * | 2017-11-23 | 2018-02-16 | 湖北文理学院 | Immobilised enzymes, its preparation method and its application in atrazine-contaminated soil is repaired |
| CN108043335A (en) * | 2018-01-29 | 2018-05-18 | 广东兴叶生物科技有限公司 | A kind of preparation method of the broken capsule of cigarette |
| CN110338301A (en) * | 2019-05-27 | 2019-10-18 | 浙江绿发饲料科技有限公司 | A kind of egg feedstuff and preparation method thereof conducive to digestion |
| CN112535181A (en) * | 2020-12-04 | 2021-03-23 | 江苏省农业科学院 | Chrysanthemum essential oil microcapsule and preparation method and application thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20110064778A1 (en) * | 2003-12-18 | 2011-03-17 | Martha Moser | Continuous multi-microencapsulation process for improving the stability and storage life of biologically active ingredients |
| CN102406197A (en) * | 2011-10-08 | 2012-04-11 | 北京中天神舟航天食品技术研究院 | Microcapsule type nutrition-fortified freeze-dried instant soup bases and preparation method thereof |
| CN103599067A (en) * | 2013-10-29 | 2014-02-26 | 盐城工学院 | W/O microemulsion, and preparation method and applications thereof |
-
2015
- 2015-09-06 CN CN201510558492.0A patent/CN105126717B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20110064778A1 (en) * | 2003-12-18 | 2011-03-17 | Martha Moser | Continuous multi-microencapsulation process for improving the stability and storage life of biologically active ingredients |
| CN102406197A (en) * | 2011-10-08 | 2012-04-11 | 北京中天神舟航天食品技术研究院 | Microcapsule type nutrition-fortified freeze-dried instant soup bases and preparation method thereof |
| CN103599067A (en) * | 2013-10-29 | 2014-02-26 | 盐城工学院 | W/O microemulsion, and preparation method and applications thereof |
Non-Patent Citations (1)
| Title |
|---|
| 郎轶咏，李峥，张晓莉，王强: "壳聚糖-海藻酸钠微球载体的制备", 《解放军药学学报》 * |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106580728A (en) * | 2017-01-17 | 2017-04-26 | 上海应用技术大学 | Vitamin C microcapsule and preparation method thereof |
| CN107384326A (en) * | 2017-07-25 | 2017-11-24 | 延安大学 | Gelatin chitosan nano silicon multinuclear microcapsules of storing energy through phase change preparation method |
| CN107384326B (en) * | 2017-07-25 | 2020-08-04 | 延安大学 | Preparation method of gelatin chitosan-nano silicon dioxide multi-core phase change energy storage microcapsule |
| CN107699558A (en) * | 2017-11-23 | 2018-02-16 | 湖北文理学院 | Immobilised enzymes, its preparation method and its application in atrazine-contaminated soil is repaired |
| CN108043335A (en) * | 2018-01-29 | 2018-05-18 | 广东兴叶生物科技有限公司 | A kind of preparation method of the broken capsule of cigarette |
| CN108043335B (en) * | 2018-01-29 | 2020-11-03 | 广东兴叶生物科技有限公司 | Preparation method of breakable capsule for cigarettes |
| CN110338301A (en) * | 2019-05-27 | 2019-10-18 | 浙江绿发饲料科技有限公司 | A kind of egg feedstuff and preparation method thereof conducive to digestion |
| CN112535181A (en) * | 2020-12-04 | 2021-03-23 | 江苏省农业科学院 | Chrysanthemum essential oil microcapsule and preparation method and application thereof |
| CN112535181B (en) * | 2020-12-04 | 2021-09-24 | 江苏省农业科学院 | Chrysanthemum essential oil microcapsule and preparation method and application thereof |
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