CN105125855A - Traditional Chinese medicine composition for matching tumor chemotherapy - Google Patents
Traditional Chinese medicine composition for matching tumor chemotherapy Download PDFInfo
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- CN105125855A CN105125855A CN201510613710.6A CN201510613710A CN105125855A CN 105125855 A CN105125855 A CN 105125855A CN 201510613710 A CN201510613710 A CN 201510613710A CN 105125855 A CN105125855 A CN 105125855A
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Abstract
The invention relates to a traditional Chinese medicine composition for matching tumor chemotherapy, which is prepared from the following traditional medicinal raw materials in parts by weight: 1-3 parts of rhizome of david woodbetony, 3-4 parts of calystegia hederacea, 3-5 parts of herb of carpet thyme, 5-10 parts of flavedo, 2-4 parts of root of small diuranthera, 1-3 parts of asclepias physocarpa, 1-3 parts of glycine max, 2-5 parts of citron, 2-5 parts of whorlleaf stonecrop herb root, 3-7 parts of acanthopanax obovatus hoo, 3-7 parts of common hawksbeard, 2-4 parts of birchleaf pear branches and leaves, 5-8 parts of fructus piperis longi root, 5-8 parts of typhonium blumei, 1-4 parts of ilex cornuta lindl, 2-3 parts of passiflora wilsonii, 1-4 parts of adenia chevali, and 2-7 parts of tendrilleaf solomonseal rhizome. The traditional Chinese medicine composition has effects of strengthening the spleen and stomach, calming the adverse-rising energy and preventing or arresting vomiting, nourishing liver and kidney, nourishing yin and promoting secretion of saliva or body liquid, smoothening and adjusting qi function, improving immunity of the organism, effectively relieving side effects of weakness, vomiting and alopecia caused by the chemotherapy and obvious in therapeutic effect.
Description
Technical field
The invention belongs to the field of Chinese medicines, be specifically related to a kind of Chinese medicine composition coordinating chemotherapy of tumors.
Background technology
The object of chemotherapy is to kill tumor cell, so chemotherapeutic cytotoxicity is stronger, dosage is larger, stronger to the lethal effect of tumor cell.Feature due to Chemotherapy is all the DNA acting on cell, so it is not optionally.To the lethal effect of tumor cell, with to Normocellular effect, such as hematopoietic cell, immunocyte, gastrointestinal tract cell, even all not optionally to liver, kidney, cause serious toxic and side effects thus, such as: leukocyte obviously reduces, gastrointestinal reaction almost makes patient not take food or to vomit, and also has liver, kidney injury etc.These side effect reduce the antineoplastic immune power of patient self on the contrary, cause the state of an illness to worsen further.
The treatment of Chinese medicine to chemotherapy of tumors harmful effect and toxic and side effects has certain advantage and the curative effect of uniqueness.As the liver function injury that chemotherapy causes, can invigorating the spleen for eliminating dampness, dispersing the stagnated liver-QI for regulating the stomach, regulating functional activities of qi, ruling by law of helping to detoxify.The bone marrow supression caused chemotherapy can fill blood, strengthening the spleen kidney, helps and controls it with blood circulation promoting and blood stasis dispelling, and note tune the five internal organs of holding concurrently ... all can receive comparatively ideal curative effect.
Summary of the invention
One is the object of the present invention is to provide effectively to alleviate chemical therapy toxic side effect, the Chinese medicine composition of cooperation chemotherapy of tumors evident in efficacy.
The technical solution adopted for the present invention to solve the technical problems is: a kind of Chinese medicine composition coordinating chemotherapy of tumors, be made up of the raw material of Chinese medicine of following weight proportioning: Rhizoma Pedicularis Davidii 1-3 part, DAWANHUA 3-4 part, Herba Thymi 3-5 part, Pericarpium Citri junoris 5-10 part, Radix Diurantherae Minoris 2-4 part, Fructus Gomphocarpi futicosi 1-3 Fen ， Semen sojae atricolor 1-3 part, Fructus Citri 2-5 part, Pedicularis rex C. B. Clarke ex Maxim. 2-5 part, Acanthopanax obouatus Hoo 3-7 part, Crepis crocea Babc.(C.turczaninowii C.A.Mey.) 3-7 part, Ramulus et folium pyri betulaefoliae 2-4 part, Radix Piperis Longi 5-8 part, Rhizoma Arisaematis Intermedii 5-8 part, Radix Ilicis Cornutae 1-4 part, Herba Passiflorae Wilsonii 2-3 part, Adenia heterophylla (Bl.) Koord.[A.che-ualieri Gagnep. 1-4 part, Rhizoma Polygonati Cirrhifolii 2-7 part.
Preferably, coordinate the Chinese medicine composition of chemotherapy of tumors, be made up of the raw material of Chinese medicine of following weight proportioning: Rhizoma Pedicularis Davidii 2 parts, DAWANHUA 3 parts, Herba Thymi 3 parts, Pericarpium Citri junoris 7 parts, Radix Diurantherae Minoris 3 parts, Fructus Gomphocarpi futicosi 3 parts, big shield bean 2 parts, Fructus Citri 2 parts, Pedicularis rex C. B. Clarke ex Maxim. 4 parts, Acanthopanax obouatus Hoo 5 parts, Crepis crocea Babc.(C.turczaninowii C.A.Mey.) 5 parts, Ramulus et folium pyri betulaefoliae 3 parts, Radix Piperis Longi 5 parts, Rhizoma Arisaematis Intermedii 7 parts, Radix Ilicis Cornutae 3 parts, Herba Passiflorae Wilsonii 3 parts, Adenia heterophylla (Bl.) Koord.[A.che-ualieri Gagnep. 2 parts, Rhizoma Polygonati Cirrhifolii 5 parts.
The pharmacologically active of each raw material of Chinese medicine of the present invention is as follows:
Rhizoma Pedicularis Davidii is the rhizome of goatweed David Radix seu Herba Pedicularis, rough Radix seu Herba Pedicularis, Deng Shi Radix seu Herba Pedicularis, Radix seu Herba Pedicularis attractive in appearance etc., sweet in the mouth, and micro-hardship is warm in nature, enriching yin and nourishing kidney; Replenishing QI to invigorate the spleen.Main asthenia of both the spleen and kidney; Osteopyrexia and fever; Arthralgia; Anorexia.
DAWANHUA is the root stock of Convolvulaceae calystegia plant DAWANHUA, sweet, light, flat, invigorating the spleen and benefiting QI, diuresis, regulating menstruation, leukorrhagia stopping; For insufficiency of the spleen dyspepsia, menoxenia, leucorrhea, milk is rare.
Herba Thymi is the thymic herb of labiate, acrid in the mouth, and property is put down, dispelling wind stopping cough; Spleen invigorating circulation of qi promoting; Dampness removing is treating stranguria.Main headache due to common cold; Cough; Pertussis; Epigastric pain; Dyspepsia; Vomiting and diarrhoea; Toothache; Difficulty and pain in micturition; Eczema pruritus; Sore, carbuncle and painful swelling." Shaanxi Chinese herbal medicine ": warming spleen and stomach for dispelling cold, strengthening the spleen to promote digestion, analgesia of dispeling the wind.Control cold syndrome of the stomach pain, little distention and fullness in the abdomen, dyspepsia, general aching, toothache.
Pericarpium Citri junoris is the peel of rutaceae Fructus Citri sinensis, pungent, bitter, and temperature, returns spleen, lung meridian, circulation of qi promoting spleen invigorating; Lowering the adverse-rising QI and eliminating phlegm.The distension and fullness in the abdomen of main stagnation of QI in spleen and stomach; Nausea and vomiting; Inappetence; Expectorant stops up the cough with copious phlegm of QI rising in reverse order; Septum pectorale is full vexed; Globus hystericus." Traditional Chinese Medicine in Sichuan will ": promoting the circulation of QI and reducing phlegm, spleen invigorating stomach warming.Control inappetence, breast abdominal distention is swollen has a pain, active borhorygmus and stool or half congealed or rush down.
Radix Diurantherae Minoris is the root of the little Diuranthera Hemsl of liliaceous plant, lightly seasoned, and property is put down, spleen invigorating removing food stagnancy; Relaxing muscles and tendons and activating QI and blood in the collateral; Removing toxic substances and promoting subsidence of swelling.Main infantile malnutrition; Lukorrhagia due to hypofunction of the spleen, arthralgia chiefly caused by damp pathogen is ached; Acute mastitis swells and ache.
Fructus Gomphocarpi futicosi is the aerial parts of trailing plants section plant Fructus Gomphocarpi futicosi, sweet, flat, returns spleen, stomach warp, invigorating the spleen and regulating the stomach; Lung benefiting.Main vomiting in children; Have loose bowels; Do not think to receive food; Pulmonary tuberculosis cough.
Semen sojae atricolor is the seed of pulse family big shield bean, tonifying speen and tonifying kidney, yin nourishing relieving restlessness.Cure mainly deficiency of YIN dysphoria with smothery sensation, spontaneous sweating, rheumatic Bi syndrome.。
Fructus Citri, be rutaceae citron or fragrant round mature fruit, pungent, bitter, acid, returns liver, lung, spleen channel, regulating QI and lowering the adverseness; The chest stuffiness relieving reduces phlegm.Main breast abdominal distention is vexed; Distending pain over the hypochondrium; Cough with copious phlegm.
Pedicularis rex C. B. Clarke ex Maxim., be the root of goatweed Pedicularis rex, taste is micro-sweet, cool in nature, returns liver, spleen channel, invigorating qi and benefiting blood; Invigorating spleen to remove dampness.Main deficiency of YIN hectic fever; Puerperal hypogalactia; Chronic hepatitis; Cirrhotic ascites; Infantile malnutrition.
Acanthopanax obouatus Hoo is root or the stem of Araliaceae Acanthopanax obouatus Hoo, sweet in the mouth, and micro-hardship is warm in nature, invigorating the spleen and benefiting QI; Kidney calming; Relaxing muscles and tendons and activating QI and blood in the collateral.Main body void is weak; Inappetence; Soreness of the waist and knees; Sexual impotence; Insomnia and dreamful sleep; Forgetful; Anemofrigid-damp arthralgia.
Crepis crocea Babc.(C.turczaninowii C.A.Mey.) is the root of feverfew Crepis phoenix Dunn, and bitter in the mouth is sweet, warm in nature, liver and kidney tonifying; Invigorating spleen to remove dampness.Master has a dizzy spell; Soreness of the waist and knees; Edema; Leukorrhagia infantile malnutrition; Hypogalactia.
Ramulus et folium pyri betulaefoliae is the branch and leaf of rosaceous plant Fructus pyri betulaefoliae, acid, sweet puckery, cold, returns large intestine channel, soothing liver-QI stomach function regulating, emergency antidiarrheal.Food is told in main regurgitation, and cholera is vomited and diarrhoea, convulsion stomachache.
Radix Piperis Longi is the root of Piperaceae plant Fructus Piperis Longi, pungent, and temperature, returns kidney, stomach warp, warming middle-JIAO to promote flow of QI; Sending down the abnormal ascending QI helps digestion; Dispersing cold for relieving pain; Preventing the attack (or recurrence) of malaria.Main invasion by pathogenic cold distension and fullness in the abdomen; Vomiting; Accumulation of food in the stomach and intes tine due to indigestion; Hernia swells; Women's infertility; Malaria.
Rhizoma Arisaematis Intermedii is the tuber of aroid Rhizoma Arisaematis Intermedii, warm in nature, acrid in the mouth, drying dampness to eliminate phlegm, stomach function regulating spleen invigorating, stopping nausea and vomiting by lowering the adverse flow of QI.Control gastritis, gastric ulcer is vomitted, cough with copious phlegm, hyperemesis.
Radix Ilicis Cornutae is the root of holly plant Ilex cornuta Lindl., bitter, cool, invigorating the liver and kidney, fresh breeze heat.Control waist knee flaccidity, arthralgia, wind syndrome of head, acute conjunctivitis, toothache.
Herba Passiflorae Wilsonii is the herb of Passifloraceae plant Passiflora wilsonii, and mildly bitter flavor is warm in nature, wind-damp dispelling; Invigorating the liver and kidney; Promoting blood flow to regulate menstruation, parasite killing preventing the attack (or recurrence) of malaria.The sliding pain of main air temperature; Sore waist and aching in the waist and the back; Hepatitis; Liver cirrhosis; Menoxenia; Traumatic injury; Fracture.
Adenia heterophylla (Bl.) Koord.[A.che-ualieri Gagnep. is the root of Passifloraceae plant Adenia heterophylla (Bl.) Koord.[A.che-ualieri Gagnep., and sweet, micro-hardship is cool, strengthening by means of tonics, wind-damp dispelling, the meridian dredging.For strengthening the spleen and stomach, invigorating the liver and kidney.
Rhizoma Polygonati Cirrhifolii is the rhizome of liliaceous plant polygonatum cirrhifolium Royle, sweet, flat, nourishing lung-YIN, invigorating the spleen and benefiting QI, hemostasis of eliminating the phlegm, subduing swelling and detoxicating.Control chronic consumptive disease cough, dizzy, lack of appetite, seminal emission, night sweat, bleeding not during menses, puerperal, body lost, and spitted blood, epistaxis, traumatic hemorrhage, laryngopharynx swelling and pain, and skin ulcer swells, scrofula." Shaanxi Chinese herbal medicine ": " spleen reinforcing lung moistening, enriching yin and nourishing kidney, promoting flow of QI and blood, astringing to arrest bleeding, sterilization of drawing out pus by applying a plaster to the affected part.Control insufficiency of the spleen few food, cough due to deficiency of the lung, dizzy bodily pain, seminal emission night sweat, metrorrhagia leucorrhea, furuncle is from the beginning of, scrofula.″
The present invention has following beneficial effect: Chinese medicine composition of the present invention has effect of invigorating the spleen and regulating the stomach, stopping nausea and vomiting by lowering the adverse flow of QI, nourishing the liver and kidney, YIN nourishing and the production of body fluid promoting, regulating air activity, improve immunity of organisms, the side effect such as weak unable, the vomiting effectively alleviating that Chemotherapy in Patients causes, alopecia, evident in efficacy.
Detailed description of the invention
Be below specific embodiments of the invention, technical scheme of the present invention is described further, but protection scope of the present invention is not limited to these embodiments.Every do not deviate from the present invention's design change or equivalent substituting include within protection scope of the present invention.
Embodiment 1
Coordinate a Chinese medicine composition for chemotherapy of tumors, be made up of the raw material of Chinese medicine of following weight proportioning: Rhizoma Pedicularis Davidii 2g, DAWANHUA 3g, Herba Thymi 3g, Pericarpium Citri junoris 7g, Radix Diurantherae Minoris 3g, Fructus Gomphocarpi futicosi 3g, big shield bean 2g, Fructus Citri 2g, Pedicularis rex C. B. Clarke ex Maxim. 4g, Acanthopanax obouatus Hoo 5g, Crepis crocea Babc.(C.turczaninowii C.A.Mey.) 5g, Ramulus et folium pyri betulaefoliae 3g, Radix Piperis Longi 5g, Rhizoma Arisaematis Intermedii 7g, Radix Ilicis Cornutae 3g, Herba Passiflorae Wilsonii 3g, Adenia heterophylla (Bl.) Koord.[A.che-ualieri Gagnep. 2g, Rhizoma Polygonati Cirrhifolii 5g.
Embodiment 2
Coordinate a Chinese medicine composition for chemotherapy of tumors, be made up of the raw material of Chinese medicine of following weight proportioning: Rhizoma Pedicularis Davidii 1g, DAWANHUA 3g, Herba Thymi 4g, Pericarpium Citri junoris 10g, Radix Diurantherae Minoris 2g, Fructus Gomphocarpi futicosi 1g, big shield bean 3g, Fructus Citri 3g, Pedicularis rex C. B. Clarke ex Maxim. 5g, Acanthopanax obouatus Hoo 6g, Crepis crocea Babc.(C.turczaninowii C.A.Mey.) 7g, Ramulus et folium pyri betulaefoliae 2g, Radix Piperis Longi 7g, Rhizoma Arisaematis Intermedii 6g, Radix Ilicis Cornutae 2g, Herba Passiflorae Wilsonii 3g, Adenia heterophylla (Bl.) Koord.[A.che-ualieri Gagnep. 4g, Rhizoma Polygonati Cirrhifolii 4g.
Embodiment 3
Coordinate a Chinese medicine composition for chemotherapy of tumors, be made up of the raw material of Chinese medicine of following weight proportioning: Rhizoma Pedicularis Davidii 3g, DAWANHUA 2g, Herba Thymi 3g, Pericarpium Citri junoris 5g, Radix Diurantherae Minoris 4g, Fructus Gomphocarpi futicosi 2g Semen sojae atricolor 1g, Fructus Citri 5g, Pedicularis rex C. B. Clarke ex Maxim. 3g, Acanthopanax obouatus Hoo 3g, Crepis crocea Babc.(C.turczaninowii C.A.Mey.) 4g, Ramulus et folium pyri betulaefoliae 4g, Radix Piperis Longi 6g, Rhizoma Arisaematis Intermedii 8g, Radix Ilicis Cornutae 1g, Herba Passiflorae Wilsonii 2g, Adenia heterophylla (Bl.) Koord.[A.che-ualieri Gagnep. 3g, Rhizoma Polygonati Cirrhifolii 2g.
Embodiment 4
Coordinate a Chinese medicine composition for chemotherapy of tumors, be made up of the raw material of Chinese medicine of following weight proportioning: Rhizoma Pedicularis Davidii 3g, DAWANHUA 4g, Herba Thymi 5g, Pericarpium Citri junoris 8g, Radix Diurantherae Minoris 2g, Fructus Gomphocarpi futicosi 2g, big shield bean 2g, Fructus Citri 4g, Pedicularis rex C. B. Clarke ex Maxim. 2g, Acanthopanax obouatus Hoo 7g, Crepis crocea Babc.(C.turczaninowii C.A.Mey.) 3g, Ramulus et folium pyri betulaefoliae 4g, Radix Piperis Longi 8g, Rhizoma Arisaematis Intermedii 5g, Radix Ilicis Cornutae 4g, Herba Passiflorae Wilsonii 2g, Adenia heterophylla (Bl.) Koord.[A.che-ualieri Gagnep. 1g, Rhizoma Polygonati Cirrhifolii 7g.
Clinical data
Physical data: clinical treatment observation is carried out to 190 routine cancer chemotherapy patients, point treatment group and matched group, treatment group 95 example, male 51 example, women 44 example, age 20-73 year, 47 years old mean age; Matched group 95 example, male 50 example, women 45 example, age 21-72 year, 48 years old mean age.
Therapeutic Method:
Treatment group: Chinese medicine composition of the present invention is decocted in water for oral dose, every day potion, one day twice, sooner or later sub-service, chemotherapy started namely to start to take, to end of chemotherapy.
Matched group is chemotherapy.
Criterion of therapeutical effect:
Cure: all malaise symptoms all disappear, energy and muscle power obviously strengthen;
Effective: all malaise symptoms alleviate or partial disappearance, energy and muscle power strengthen;
Invalid: malaise symptoms is unchanged.
Therapeutic outcome: therapeutic outcome statistics is as following table.
| Group | Case load | Cure | Effectively | Invalid | Cure rate | Total effective rate |
| Matched group | 95 | 20 | 35 | 40 | 21.1％ | 57.9％ |
| Treatment group | 95 | 70 | 18 | 7 | 73.7％ | 92.6％ |
Chinese medicine composition of the present invention is for the malaise symptoms curative effect after treatment chemotherapy of tumors apparently higher than matched group, and effective percentage is high, the side effect such as weak unable, the vomiting effectively alleviating that Chemotherapy in Patients causes, alopecia, the effectively life quality of raising patient.
Claims (2)
1. coordinate a Chinese medicine composition for chemotherapy of tumors, it is characterized in that, be made up of the raw material of Chinese medicine of following weight proportioning: Rhizoma Pedicularis Davidii 1-3 part, DAWANHUA 3-4 part, Herba Thymi 3-5 part, Pericarpium Citri junoris 5-10 part, Radix Diurantherae Minoris 2-4 part, Fructus Gomphocarpi futicosi 1-3 part, big shield bean 1-3 part, Fructus Citri 2-5 part, Pedicularis rex C. B. Clarke ex Maxim. 2-5 part, Acanthopanax obouatus Hoo 3-7 part, Crepis crocea Babc.(C.turczaninowii C.A.Mey.) 3-7 part, Ramulus et folium pyri betulaefoliae 2-4 part, Radix Piperis Longi 5-8 part, Rhizoma Arisaematis Intermedii 5-8 part, Radix Ilicis Cornutae 1-4 part, Herba Passiflorae Wilsonii 2-3 part, Adenia heterophylla (Bl.) Koord.[A.che-ualieri Gagnep. 1-4 part, Rhizoma Polygonati Cirrhifolii 2-7 part.
2. the Chinese medicine composition coordinating chemotherapy of tumors as claimed in claim 1, is characterized in that, be made up of the raw material of Chinese medicine of following weight proportioning: Rhizoma Pedicularis Davidii 2 parts, DAWANHUA 3 parts, Herba Thymi 3 parts, Pericarpium Citri junoris 7 parts, Radix Diurantherae Minoris 3 parts, Fructus Gomphocarpi futicosi 3 parts, big shield bean 2 parts, Fructus Citri 2 parts, Pedicularis rex C. B. Clarke ex Maxim. 4 parts, Acanthopanax obouatus Hoo 5 parts, Crepis crocea Babc.(C.turczaninowii C.A.Mey.) 5 parts, Ramulus et folium pyri betulaefoliae 3 parts, Radix Piperis Longi 5 parts, Rhizoma Arisaematis Intermedii 7 parts, Radix Ilicis Cornutae 3 parts, Herba Passiflorae Wilsonii 3 parts, Adenia heterophylla (Bl.) Koord.[A.che-ualieri Gagnep. 2 parts, Rhizoma Polygonati Cirrhifolii 5 parts.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106668553A (en) * | 2017-03-21 | 2017-05-17 | 王翠翠 | Traditional Chinese medicine for alleviating side effects of chemotherapy |
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| CN103142894A (en) * | 2011-12-07 | 2013-06-12 | 山东东阿阿胶股份有限公司 | Traditional Chinese medicine composition for rehabilitation of tumor patients after radiotherapy and chemotherapy, and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103142894A (en) * | 2011-12-07 | 2013-06-12 | 山东东阿阿胶股份有限公司 | Traditional Chinese medicine composition for rehabilitation of tumor patients after radiotherapy and chemotherapy, and preparation method thereof |
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| 李培训: "中医药治疗恶性肿瘤化疗后白细胞减少症", 《天津中医药》 * |
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