CN105125250B - The embolization device of auxiliary Aneurysmal neck - Google Patents

The embolization device of auxiliary Aneurysmal neck Download PDF

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Publication number
CN105125250B
CN105125250B CN201510631421.9A CN201510631421A CN105125250B CN 105125250 B CN105125250 B CN 105125250B CN 201510631421 A CN201510631421 A CN 201510631421A CN 105125250 B CN105125250 B CN 105125250B
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CN
China
Prior art keywords
embolization device
device body
seal wire
embolization
assistor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201510631421.9A
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Chinese (zh)
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CN105125250A (en
Inventor
黄清海
刘建民
沈洁
王驰
吕楠
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Second Military Medical University SMMU
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Second Military Medical University SMMU
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Priority to CN201510631421.9A priority Critical patent/CN105125250B/en
Publication of CN105125250A publication Critical patent/CN105125250A/en
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12099Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder
    • A61B17/12109Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel
    • A61B17/12113Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel within an aneurysm
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12027Type of occlusion
    • A61B17/12031Type of occlusion complete occlusion
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12131Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
    • A61B17/12168Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device having a mesh structure
    • A61B17/12172Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device having a mesh structure having a pre-set deployed three-dimensional shape

Abstract

The present invention relates to a kind of embolization device of auxiliary Aneurysmal neck, the embolization device includes microtubular, fixed seal wire, develop seal wire, embolization device body, assistor;Described development seal wire is fixed on the assistor of embolization device body distal end;The fixed seal wire passes through inside assistor and microtubular;Under described embolization device body deployed condition, two ends are in infundibulate, and frustoconical bevel angle is 20 70 degree;The embolization device body is woven into the stereoeffect of grid by 8 20 memory metal silk materials;The deformation quantity of the metal wire material of the embolization device pars intermedia projects to form projection;The raised angle is 110 160 degree.Its advantage shows:The safety for the treatment of is improve, wound is little;The secondary spring circle thromboembolism in parent artery is can support when simple Coil embolization aneurysm is more difficult, thromboembolism can be recycled to after finishing completely in vitro;Thromboembolism is aided in avoid the shortcoming that long-time blocking parent artery blood flow causes ischemic complications compared to sacculus.

Description

The embolization device of auxiliary Aneurysmal neck
Technical field
The present invention relates to technical field of medical instruments, specifically, is a kind of embolization device of auxiliary Aneurysmal neck.
Background technology
The tube wall of vascular system, particularly arterial blood tube wall, may form entitled aneurysmal morbid state expansion.Generally see The aneurysm for observing is the cryptomere projection (ballooning-out) that arterial blood tube wall is formed.This is, by disease, to damage or congenital Sexual abnormality and weaken the result of blood vessel wall.Aneurysm possesses thin, illusive tube wall, and has a kind of trend of rupture, Generally caused or be degraded by hypertension.Aneurysm can be found in the different piece of body;Most commonly ventral aorta Aneurysm (abdominal aortic aneurysms, AAA) and cerebral aneurysm.
Research shows, endovascular treatment is cerebral aneurysm safely and effectively Therapeutic Method, and most aneurysms can be led to Cross interventional embolization to be effectively treated.Recently as being situated between in developing rapidly for material science and interventional radiology, blood vessel pipe Entering treatment has become aneurysmal prefered method.But to wide neck, fusiformis, interlayer, huge, small and multiple aneurysm etc. A difficult problem is remained during the treatment of complicated tremulous pulse.Its operation of opening cranium difficulty is big, and during simple use Coil embolization, Turn may be charged into parent artery and cause the obturation of parent artery or its branch vessel, and then cause neurological deficit, Or even threat to life.
At present for the treatment of intracranial wide-necked aneurysms, mainly include using sacculus embolization and support auxiliary bullet Spring coil carries out embolotherapy, and sacculus auxiliary thromboembolism refers to that turn is inserted aneurysmal tumor chamber under sacculus protection by parent artery It is interior, but sacculus long-time blocking parent artery blood flow causes ischemic complications, and cause to move in tumor cervical region position dilating sacculus Arteries and veins inner film injury, has the danger for being subsequently formed thrombosis.
Support secondary spring circle carries out embolotherapy support mainly the Neuroform of Boston Scientific companies Support, the LEO supports of Blat companies, the Enterprise supports of Johson & Johnson, the solitaireAB supports of Ev3 companies, but Frame implantation postoperative patient needs Long-term Oral anticoagulant, and to avoid the generation of in-stent restenosis, this not only increased Jing to patient Ji burden, and the bleeding that brought of Long-term Oral anticoagulant and other side effect are also the problem that can not be ignored;And support is soft Pliable difference, stent diameter are non-adjustable, are not easy to withdraw.
In sum, need one kind badly and need not take anticoagulant, compliance is good, and diameter is adjustable, be easy to withdraw, fine and close filling tumor Neck, it is ensured that the embolization device of the unobstructed auxiliary Aneurysmal neck of parent artery, and report is yet there are no with regard to this embolization device Road.
The content of the invention
The purpose of the present invention is for deficiency of the prior art, there is provided one kind need not take anticoagulant, and compliance is good, directly Footpath is adjustable, is easy to withdraw, fine and close filling tumor neck, it is ensured that the embolization device of the unobstructed auxiliary Aneurysmal neck of parent artery.
For achieving the above object, the present invention is adopted the technical scheme that:
A kind of embolization device of auxiliary Aneurysmal neck, the embolization device include that microtubular, fixed seal wire, development are led Silk, embolization device body, assistor;Described development seal wire is fixed on the assistor of embolization device body distal end;It is described solid Determine seal wire to pass through inside assistor and microtubular;Under described embolization device body deployed condition, two ends are in infundibulate, and the conical surface Angle is 20-70 degree;The embolization device body is woven into the stereoeffect of grid by 8-20 root memory metal silk materials;Institute The deformation quantity for stating the metal wire material of embolization device pars intermedia projects to form projection;The raised angle is 110-160 degree.
Described microtubular is hollow structure.
The assistor has two, respectively positioned at embolization device body two ends.
Described fixed seal wire is to be fixedly connected with the distal end of embolization device body, and the near-end with embolization device body is work Dynamic connection.
The embolization device body two ends grid pore diameter range is 120-900 μm, and intermediate mesh pore diameter range is 40-300 μ m。
The raised width is 6-12mm.
Developing agent is scribbled on the fixed seal wire and development seal wire.
Fit with parent artery inwall under described embolization device body deployed condition.
The invention has the advantages that:
1st, a kind of embolization device of auxiliary Aneurysmal neck of the invention, improves the safety for the treatment of, and wound is little;
2nd, embolization device compliance is good, and portion can form projection in the body, is easy to fine and close filling tumor neck, contributes to aneurysm Treatment;Between hole, stereochemical structure embolization device body is acted on to the turn Auxiliary support in arteries and veins tumor, increases stablizing for turn Property, while ensureing that parent artery is unobstructed;Development seal wire has the function of development, its objective is to be easy to auxiliary positioning;
3rd, embolization device body two ends are in funnel-form, on the one hand ensure that parent artery is unobstructed, on the other hand funnelform bolt Plug device body contributes to withdrawing;
5th, can be recycled to completely after thromboembolism is finished external, it is to avoid embolization device is trapped in parent artery by body and causes concurrent Disease;
6th, aid in thromboembolism to avoid long-time blocking parent artery blood flow compared to sacculus and cause lacking for ischemic complications Point;
7th, embolization device body two ends grid is sparse, middle intensive so that embolization device body has good compliance, Enough flexibly to deform very tortuous blood vessel through in brain, and while provide enough convex covering surfaces to seal aneurysm Tumor neck.
Description of the drawings
Accompanying drawing 1 is that the embolization device body deployed configuration in a kind of embolization device of auxiliary Aneurysmal neck of the present invention shows It is intended to.
Accompanying drawing 2 is that the embolization device body withdrawal structure in a kind of embolization device of auxiliary Aneurysmal neck of the present invention is shown It is intended to.
Specific embodiment
Below in conjunction with the accompanying drawings the specific embodiment that the present invention is provided is elaborated.
The reference and ingredient being related in accompanying drawing is as follows:
1. microtubular 2. fixes seal wire
3rd, develop 4. embolization device body of seal wire
41. grids 42. are raised
5. 6. aneurysm of assistor
7. 8. parent artery of tumor neck
Embodiment 1
Fig. 1 is refer to, Fig. 1 is a kind of embolization device structural representation of auxiliary Aneurysmal neck of the present invention.It is a kind of auxiliary The embolization device of 6 tumor neck 7 of aneurysm, the embolization device is helped to include microtubular 1, fixed seal wire 2, development seal wire 3, embolization device Body 4, assistor 5, development seal wire 3;Described development seal wire 3 is fixed on the assistor 5 of 4 distal end of embolization device body;Institute State fixed seal wire 2 to pass through inside assistor 5 and microtubular 1;Developing agent is scribbled on the fixed seal wire 2 and development seal wire 3;It is described 4 deployed condition of embolization device body under two ends be in infundibulate, and frustoconical bevel angle be 20-70 degree;The embolization device body 4 by 8-20 root memory metal silk materials are woven into the stereoeffect of grid 41, and 4 two ends grid 41 of embolization device body is sparse, middle Intensive, grid 41 pore diameter range in two ends is 120-900 μm, and 41 pore diameter range of intermediate mesh is 40-300 μm;The thromboembolism dress is originally Metal wire material in the middle part of body can be better than the metal wire material at two ends, described embolization device body 4 through PROCESS FOR TREATMENT, its deformation quantity Fit with 8 inwall of parent artery under deployed condition, the deformation quantity of the metal wire material of pars intermedia projects to form raised 42;The projection 42 width is 6-12mm;Raised 42 angle is 110-160 degree, raised 42 with tumor neck 7 mouthfuls be engaged.
Fig. 2 is refer to, 2 is that the embolization device body in a kind of embolization device of auxiliary Aneurysmal neck of the present invention withdraws Structural representation.Described microtubular 1 is hollow structure, for conveying or withdrawing embolization device body 4.
It should be noted that:The assistor 5 has two, respectively positioned at 4 two ends of embolization device body, its objective is solid Determine embolization device body 4;Described fixed seal wire 2 is to be fixedly connected with the distal end of embolization device body 4, with embolization device body To be flexibly connected, during use, when fixed seal wire 2 is promoted forward, embolization device body 4 is pushed away 4 near-end fixed seal wire 2 Under dynamic, pass microtubular 1, because embolization device body 4 is passed after microtubular 1 not by external force extruding, in addition embolization device body 4 by Memory wire braiding is formed, and now embolization device body 4 can be expanded outwardly, and be close to 8 inwall of parent artery.Its memory wire Material preferable temperature is 30-38 degree, and its temperature range is the temperature in parent artery 8.When withdrawing embolization device body 4, fixation is led Silk 2 is pushed out, you can embolization device body 4 is retracted in microtubular 1, in addition, the diameter of embolization device body 4 is by solid Determine seal wire 2 to adjust, seal wire is promoted forward, 4 diameter of embolization device body diminishes, fixed seal wire 2 is pushed out, embolization device The diameter of body 4 becomes big, so that embolization device body 4 is close to 8 inwall of parent artery, preferably support spring circle;It is described Development seal wire 3 have development function, its objective is to be easy to auxiliary positioning.
The embolization device body 4 is acted on of both mainly having, and is on the one hand to ensure that parent artery 8 is unobstructed, the opposing party Face is fine and close filling tumor neck 7.Specially:Between hole, stereochemical structure embolization device body 4 is to the turn Auxiliary support in aneurysm Effect, increases the stability of turn, it is ensured that parent artery 8 is unobstructed, it is to avoid turn may be charged into parent artery 8 and cause to carry The obturation of tumor tremulous pulse 8 or its branch vessel, and then cause neurological deficit, or even threat to life.
Embolization device body 4 mainly includes the following aspects in fine and close filling tumor neck 7:First, the gold of embolization device body 4 Category silk material is very submissive, when under expansion state, can be formed and 7 mouthfuls of projections 42 for matching of tumor neck, be easy to 7 densification of tumor neck to fill out Plug;2nd, 4 two ends of embolization device body are 20-70 degree in funnel-form, the i.e. frustoconical bevel angle of embolization device body 4 so which is to carrying In tumor tremulous pulse 8, normal blood flow affects very little, it is to avoid the various complication that long-time occluded blood vessel is brought.
The grid 41 of the embolization device body 4 is formed by the braiding of 8-20 root memory metals silk material, and axial 41 jiaos of grid Spend for 20-170 degree, embolization device body 4 has good compliance, enough flexibly deforming through very tortuous in brain Blood vessel, and while provide enough 42 coverage rates of projection to seal the tumor neck 7 of aneurysm 6.
A kind of embolization device using method of auxiliary Aneurysmal neck of the present invention is:Before inserting, by embolization device sheet Body 4 is retracted in microtubular 1, when inserting, judges the position of microtubular 1 and aneurysm 6 by the seal wire 3 that develops, and band microtubular 1 reaches Suitable position, promotes forward fixed seal wire 2 so that embolization device body 4 spreads out of microtubular 1, while outwards discharging;Rationally control Seal wire processed causes central raised the 42 of embolization device body 4 to be engaged with the tumor neck 7 of aneurysm 6;Retraction mechanism sheet is needed finally During body, only fixed seal wire 2 need to be pushed out, you can embolization device body 4 is retracted in microtubular 1.
A kind of embolization device of auxiliary Aneurysmal neck of the present invention, improves the safety for the treatment of, and wound is little;Thromboembolism is filled Put 1 compliance of body good, raised 42 can be formed in the middle part of embolization device body, be easy to fine and close filling tumor neck 7, contribute to aneurysm 6 treatment;Between hole, stereochemical structure embolization device body 4 is acted on to the turn Auxiliary support in arteries and veins tumor, increases the steady of turn It is qualitative, while ensureing that parent artery 8 is unobstructed;Development seal wire 3 has the function of development, its objective is to be easy to auxiliary positioning;Thromboembolism 4 two ends of device body are in funnel-form, on the one hand ensure that parent artery 8 is unobstructed, and on the other hand funnelform embolization device body 4 has Help withdraw;Thromboembolism can be recycled to after finishing in vitro completely, it is to avoid embolization device is trapped in parent artery 8 by body and causes concurrent Disease;Thromboembolism is aided in avoid the shortcoming that long-time blocking 8 blood flow of parent artery causes ischemic complications compared to sacculus;Thromboembolism 4 two ends grid of device body is sparse, middle intensive so that embolization device body 4 has good compliance, enough flexibly with change Shape is through blood vessel very tortuous in brain, and while provides enough convex covering surfaces to seal the tumor neck 7 of aneurysm 6.
The above is only the preferred embodiment of the present invention, it is noted that for the ordinary skill people of the art Member, on the premise of without departing from the inventive method, can also make some improvement and supplement, and these improve and supplement also should be regarded as Protection scope of the present invention.

Claims (8)

1. it is a kind of auxiliary Aneurysmal neck embolization device, it is characterised in that the embolization device include microtubular, fixation lead Silk, development seal wire, embolization device body, assistor;Described development seal wire is fixed on the assistor of embolization device body distal end On;The fixed seal wire passes through inside assistor and microtubular;Under described embolization device body deployed condition, two ends are in funnel Shape, and frustoconical bevel angle is 20-70 degree;The embolization device body is stood by the space that 8-20 root memory metal silk materials are woven into grid Body structure, embolization device body two ends grid are sparse, middle intensive;Metal wire material in the middle part of the embolization device body is through work Skill process, its deformation quantity can be better than two ends metal wire material, under described embolization device body deployed condition with parent artery in Wall is fitted, and the deformation quantity of the metal wire material of pars intermedia projects to form projection, makes middle part and the Aneurysmal neck of embolization device body It is engaged;The raised angle is 110-160 degree.
2. embolization device according to claim 1, it is characterised in that described microtubular is hollow structure.
3. embolization device according to claim 1, it is characterised in that the assistor has two, respectively positioned at thromboembolism Device body two ends.
4. embolization device according to claim 1, it is characterised in that described fixed seal wire is remote with embolization device body Hold to be fixedly connected, be to be flexibly connected with the near-end of embolization device body.
5. embolization device according to claim 1, it is characterised in that the embolization device body two ends grid pore diameter range For 120-900 μm, intermediate mesh pore diameter range is 40-300 μm.
6. embolization device according to claim 1, it is characterised in that the raised width is 6-12mm.
7. embolization device according to claim 1, it is characterised in that scribble development on the fixed seal wire and development seal wire Agent.
8. embolization device according to claim 1, it is characterised in that with load under described embolization device body deployed condition Tumor Wall of Artery is fitted.
CN201510631421.9A 2015-09-29 2015-09-29 The embolization device of auxiliary Aneurysmal neck Expired - Fee Related CN105125250B (en)

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CN105125250B true CN105125250B (en) 2017-04-05

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CN112741691B (en) * 2020-12-31 2022-05-13 杭州脉流科技有限公司 Spring coil coiled support release simulation method and device, computer equipment and storage medium

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