CN105055377A - Scar sheet and preparation technology thereof - Google Patents
Scar sheet and preparation technology thereof Download PDFInfo
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- CN105055377A CN105055377A CN201510494817.3A CN201510494817A CN105055377A CN 105055377 A CN105055377 A CN 105055377A CN 201510494817 A CN201510494817 A CN 201510494817A CN 105055377 A CN105055377 A CN 105055377A
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Abstract
The invention relates to a scar sheet. The scar sheet comprises a silica gel paster and an anti-adhesion film, wherein the silica gel paster comprises a backing layer and a gel layer; the gel layer is a mixture of lavender essential oil, divinyl polydimethyl siloxane, polydimethyl siloxane and ethyl-p-hydroxybenzoate; the backing layer is a silicone rubber film; the anti-adhesion film is a PE (polyethylene) film or release paper coated with silicon oil; the outer surface of the anti-adhesion film is covered with a waterproof plastic film. The scar sheet can be directly attached to a scar and is convenient to use; the silicone rubber backing layer has high adhesive force and is not prone to fall off; an enhancing layer is further arranged between the backing layer and the gel layer, so that a product has good durability; multiple medical ingredients are added to the gel layer and can effectively prevent wound infection, and the scar softening, flattening and fading time is shortened.
Description
Technical field
The invention relates to field of medical article technology, specifically refers to a kind of scar plaster and preparation technology thereof.
Background technology
Cicatrix is the inevitable outcome after various wound healing, if but healing is not enough or healing is excessive, and namely can produce cicatrix, if trace continues propagation, can hypertrophic cicatrix be become.According to the various extent of injury causing damage factor, and the body constitution of wounded body, following a few class cicatrix can be caused: show shallow scars, atrophic cicatrix, depressed scar, hypertrophic cicatrix, keloid, particularly the people of cicatrix body constitution, cicatrix is especially obvious.Cicatrix can bring great inconvenience to patient, as the hypertrophic cicatrix caused of burning, can cause local pruritus, pain, even dysfunction, seriously perplex patient.And the control of cicatrix, be a difficult problem of medical domain, although injection hormone effect is better in cicatrix, the early stage sufferings remission of cicatrix is not obvious always, and be not suitable for the control of large area cicatrix, side effect is large, and patient not easily accepts.
Easily come off in existing scar plaster use procedure, and weak to wound hydration, and easily anaphylaxis occurs, sometimes also bacteriological infection may occur, therefore, result of use is unsatisfactory.
Summary of the invention
The invention makes improvements for above-mentioned prior art Problems existing, namely the technical problem that the invention will solve is to provide a kind of scar plaster and preparation technology thereof, easy to use, Durable comfortable, effectively prevent wound infection, shorten cicatrix and soften the time flattening and fade.
For solving the problems of the technologies described above, the technical scheme of the invention is achieved in that
A kind of scar plaster, comprises silicone gel paster and antiadhesion barrier; Described silicone gel paster comprises backing layer and gel layer; Described gel layer is the mixture of Herba Lysimachiae foenum-graeci quintessence oil, divinyl polydimethylsiloxane, polydimethylsiloxane, P-hydroxybenzoic acid second vinegar.
Further, described backing layer is silicone rubber membrane.
Further, described antiadhesion barrier is PE film or the release paper scribbling silicone oil.
Further, described antiadhesion barrier outer surface is coated with one deck waterproof plastic film.
Further, also enhancement Layer is provided with between described backing layer and gel layer; Described enhancement Layer is nonwoven layer or polyurethane film.
Further, the extract of Radix Sophorae Flavescentis or Herba Centellae is added with in described gel layer.
Further, Herba Menthae or Radix Salviae Miltiorrhizae is added with in described gel layer.
Prepare a technique for scar plaster, comprise the steps:
1. first the polydimethylsiloxane of 20% is placed in agitator, then adds 5% Herba Lysimachiae foenum-graeci quintessence oil, stir, obtain A liquid for subsequent use;
2. 25% divinyl polydimethylsiloxane, obtains B liquid for subsequent use;
3. 10% ethanol is placed in beaker, adds 30% ethylparaben, stir, obtain C liquid for subsequent use;
4. A liquid, B liquid and C liquid are mixed, uniform stirring in a vacuum, obtains gel-type vehicle;
5. by step 4. in gel-type vehicle be placed in coating machine, be uniformly coated on backing layer and form gel layer, the other side then differing from backing layer at gel layer covers antiadhesion barrier, after naturally standing, obtains scar plaster base material;
6. to step 5. in scar plaster base material cut, obtain scar plaster finished product;
7. scar plaster product inspection qualified after pack.
The advantage that the invention has and good effect are:
1) this scar plaster directly can be attached on cicatrix, easy to use, the backing layer adhesion strength of silicone rubber is strong, not easily makes product come off.
2) be also provided with enhancement Layer between backing layer and gel layer, make this product ruggedness good.
3) in gel layer, be added with multi-medicament composition, effectively prevent wound infection, shorten cicatrix and soften the time flattening and fade.
Accompanying drawing explanation
Fig. 1 is this scar plaster preparation technology schematic flow sheet.
Detailed description of the invention
Below in conjunction with Figure of description and embodiment, the detailed description of the invention of the invention is described in further detail:
A kind of scar plaster, comprises silicone gel paster and antiadhesion barrier; Described silicone gel paster comprises backing layer and gel layer; Described gel layer is the mixture of Herba Lysimachiae foenum-graeci quintessence oil, divinyl polydimethylsiloxane, polydimethylsiloxane, P-hydroxybenzoic acid second vinegar.
It should be noted that, Herba Lysimachiae foenum-graeci quintessence oil effectively can desalinate cicatrix.Divinyl polydimethylsiloxane has excellent dispersion, absorption and lubricating ability, polydimethylsiloxane is very good to the permeability of skin, hydration is strong, and be applicable to quick release and the transdermal of medicine, P-hydroxybenzoic acid second vinegar has good bacteriostasis to antibacterials such as mycetes.
Wherein, described backing layer is silicone rubber membrane, and adhesion strength is strong, not easily makes product come off.
Wherein, described antiadhesion barrier is PE film or the release paper scribbling silicone oil.In addition, described antiadhesion barrier outer surface can also cover one deck waterproof plastic film.Available protecting silicone gel paster is not by outside contamination, and water resistance is good.
Wherein, also enhancement Layer is provided with between described backing layer and gel layer; Described enhancement Layer is nonwoven layer or polyurethane film.Make this product ruggedness good, can not damage easily.
Wherein, in described gel layer, be added with the extract of Radix Sophorae Flavescentis or Herba Centellae, can antalgesic-antipruritic, blood circulation promoting and blood stasis dispelling, effectively weakens cicatrix.
Wherein, be added with Herba Menthae or Radix Salviae Miltiorrhizae in described gel layer, effectively prevent wound infection, shorten cicatrix and soften the time flattening and fade.
The using method of this scar plaster is, first by clean for illing skin clean, then peels off antiadhesion barrier, then the one side of gel layer is applied to cicatrix affected part.Can change 2 to 3 times every day, until sufferings disappear, cicatrix softens, remove the skin cleaning cicatrix affected part when applying ointment or plaster this scar plaster for the first time, all the other all do not need to clean when changing scar plaster again, ensure the continual abundant and contact skin of medicine on gel layer, reach best curative effect.In use, if find, symptom does not disappear, and color and luster increases the weight of, and has no the situation of improvement with sufferings, should stop using immediately.
Prepare a technique for scar plaster, comprise the steps:
1. first the polydimethylsiloxane of 20% is placed in agitator, then adds 5% Herba Lysimachiae foenum-graeci quintessence oil, stir, obtain A liquid for subsequent use;
2. 25% divinyl polydimethylsiloxane, obtains B liquid for subsequent use;
3. 10% ethanol is placed in beaker, adds 30% ethylparaben, stir, obtain C liquid for subsequent use;
4. A liquid, B liquid and C liquid are mixed, uniform stirring in a vacuum, obtains gel-type vehicle;
5. by step 4. in gel-type vehicle be placed in coating machine, be uniformly coated on backing layer and form gel layer, the other side then differing from backing layer at gel layer covers antiadhesion barrier, after naturally standing, obtains scar plaster base material;
6. to step 5. in scar plaster base material cut, obtain scar plaster finished product;
7. scar plaster product inspection qualified after pack.
It should be noted that, Silica hydrogel is a kind of soft, translucent, sticking colloid of tool, and the surface adhesion of Silica hydrogel is greater than 10g/cm2, and loss on drying is no more than 3%, and the difference of dissolution fluid and blank solution pH value is no more than 1.5; Silica hydrogel cytotoxicity should be not more than 1 grade, should without sensitivity response, should without skin wound repair, and the total number of bacteria≤100cfu/g of product, must not detect pathogenic bacterium.
To those skilled in the art, obvious the invention is not limited to the details of above-mentioned one exemplary embodiment, and when not deviating from spirit or the basic feature of the invention, can realize the invention in other specific forms.
Therefore, no matter from which point, all should embodiment be regarded as exemplary, and be nonrestrictive, the scope of the invention is limited by claims instead of above-mentioned explanation, and all changes be therefore intended in the implication of the equivalency by dropping on claim and scope are included in the invention.Any Reference numeral in claim should be considered as the claim involved by limiting.
In addition, be to be understood that, although this description is described according to embodiment, but not each embodiment only comprises an independently technical scheme, this narrating mode of description is only for clarity sake, those skilled in the art should by description integrally, and the technical scheme in each embodiment also through appropriately combined, can form other embodiments that it will be appreciated by those skilled in the art that.
Claims (8)
1. a scar plaster, is characterized in that: comprise silicone gel paster and antiadhesion barrier; Described silicone gel paster comprises backing layer and gel layer; Described gel layer is the mixture of Herba Lysimachiae foenum-graeci quintessence oil, divinyl polydimethylsiloxane, polydimethylsiloxane, P-hydroxybenzoic acid second vinegar.
2. a kind of scar plaster according to claim 1, is characterized in that: described backing layer is silicone rubber membrane.
3. a kind of scar plaster according to claim 1, is characterized in that: described antiadhesion barrier is PE film or the release paper scribbling silicone oil.
4. a kind of scar plaster according to claim 1 or 4, is characterized in that: described antiadhesion barrier outer surface is coated with one deck waterproof plastic film.
5. a kind of scar plaster according to claim 1, is characterized in that: be also provided with enhancement Layer between described backing layer and gel layer; Described enhancement Layer is nonwoven layer or polyurethane film.
6. a kind of scar plaster according to claim 1, is characterized in that: the extract being added with Radix Sophorae Flavescentis or Herba Centellae in described gel layer.
7. a kind of scar plaster according to claim 1, is characterized in that: be added with Herba Menthae or Radix Salviae Miltiorrhizae in described gel layer.
8. the preparation technology of a kind of scar plaster according to claim 1, is characterized in that, comprise the steps:
1. first the polydimethylsiloxane of 20% is placed in agitator, then adds 5% Herba Lysimachiae foenum-graeci quintessence oil, stir, obtain A liquid for subsequent use;
2. 25% divinyl polydimethylsiloxane, obtains B liquid for subsequent use;
3. 10% ethanol is placed in beaker, adds 30% ethylparaben, stir, obtain C liquid for subsequent use;
4. A liquid, B liquid and C liquid are mixed, uniform stirring in a vacuum, obtains gel-type vehicle;
5. by step 4. in gel-type vehicle be placed in coating machine, be uniformly coated on backing layer and form gel layer, the other side then differing from backing layer at gel layer covers antiadhesion barrier, after naturally standing, obtains scar plaster base material;
6. to step 5. in scar plaster base material cut, obtain scar plaster finished product;
7. scar plaster product inspection qualified after pack.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510494817.3A CN105055377A (en) | 2015-08-13 | 2015-08-13 | Scar sheet and preparation technology thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510494817.3A CN105055377A (en) | 2015-08-13 | 2015-08-13 | Scar sheet and preparation technology thereof |
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| CN105055377A true CN105055377A (en) | 2015-11-18 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201510494817.3A Pending CN105055377A (en) | 2015-08-13 | 2015-08-13 | Scar sheet and preparation technology thereof |
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Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107648358A (en) * | 2017-11-22 | 2018-02-02 | 蚌埠崇迪生物科技有限公司 | It is a kind of defervescence plaster used and preparation method thereof |
| CN107890582A (en) * | 2017-11-27 | 2018-04-10 | 刘名倬 | A kind of Silica hydrogel Combined with Chinese Herbal prescription controls the preparation method of scar dressing |
| CN107929818A (en) * | 2017-12-21 | 2018-04-20 | 中美之光国际医疗投资管理（北京）有限公司 | New medical silicone pad pasting for meeting partes corporis humani position shape of a kind of dimethyl siloxane and preparation method thereof |
| CN109125913A (en) * | 2018-11-05 | 2019-01-04 | 王云鹏 | A kind of medical scar plaster of drug containing and preparation method thereof |
| CN109852333A (en) * | 2017-11-30 | 2019-06-07 | 山东朱氏药业集团有限公司 | A kind of Silica hydrogel preparation process of scar plaster |
| CN109847055A (en) * | 2018-12-29 | 2019-06-07 | 济南秦鲁药业科技有限公司 | Medical scar plaster and preparation method thereof |
| CN109848019A (en) * | 2017-11-30 | 2019-06-07 | 山东朱氏药业集团有限公司 | A kind of Silica hydrogel coating process of scar plaster |
| CN110917179A (en) * | 2019-12-19 | 2020-03-27 | 温州医科大学附属第一医院 | Scar-resistant silicone gel patch and preparation method thereof |
| CN111481347A (en) * | 2020-04-09 | 2020-08-04 | 苏州汇涵医用科技发展有限公司 | Silica gel scar plaster and preparation method thereof |
| CN114432273A (en) * | 2021-12-22 | 2022-05-06 | 德州昌诚新材料有限公司 | Preparation method of silica gel plaster |
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| CN1520792A (en) * | 2003-02-13 | 2004-08-18 | 上海东月医疗保健用品有限公司 | Filling type fortified scar plaster and method for making same |
| CN202426723U (en) * | 2011-12-27 | 2012-09-12 | 李国明 | Medical scar treatment strip |
| CN103083282A (en) * | 2011-11-03 | 2013-05-08 | 杭州炬九生物科技有限公司 | Novel hydrogel scar patch and its preparation process |
| CN103126951A (en) * | 2013-01-18 | 2013-06-05 | 无限极（中国）有限公司 | Compound essential oil having skin-protection effect and preparation method thereof |
| CN103127213A (en) * | 2011-12-02 | 2013-06-05 | 贵州金玖生物技术有限公司 | Dressing for removing scars |
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2015
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| CN1520792A (en) * | 2003-02-13 | 2004-08-18 | 上海东月医疗保健用品有限公司 | Filling type fortified scar plaster and method for making same |
| CN103083282A (en) * | 2011-11-03 | 2013-05-08 | 杭州炬九生物科技有限公司 | Novel hydrogel scar patch and its preparation process |
| CN103127213A (en) * | 2011-12-02 | 2013-06-05 | 贵州金玖生物技术有限公司 | Dressing for removing scars |
| CN202426723U (en) * | 2011-12-27 | 2012-09-12 | 李国明 | Medical scar treatment strip |
| CN103126951A (en) * | 2013-01-18 | 2013-06-05 | 无限极（中国）有限公司 | Compound essential oil having skin-protection effect and preparation method thereof |
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107648358A (en) * | 2017-11-22 | 2018-02-02 | 蚌埠崇迪生物科技有限公司 | It is a kind of defervescence plaster used and preparation method thereof |
| CN107890582A (en) * | 2017-11-27 | 2018-04-10 | 刘名倬 | A kind of Silica hydrogel Combined with Chinese Herbal prescription controls the preparation method of scar dressing |
| CN109852333A (en) * | 2017-11-30 | 2019-06-07 | 山东朱氏药业集团有限公司 | A kind of Silica hydrogel preparation process of scar plaster |
| CN109848019A (en) * | 2017-11-30 | 2019-06-07 | 山东朱氏药业集团有限公司 | A kind of Silica hydrogel coating process of scar plaster |
| CN107929818A (en) * | 2017-12-21 | 2018-04-20 | 中美之光国际医疗投资管理（北京）有限公司 | New medical silicone pad pasting for meeting partes corporis humani position shape of a kind of dimethyl siloxane and preparation method thereof |
| CN109125913A (en) * | 2018-11-05 | 2019-01-04 | 王云鹏 | A kind of medical scar plaster of drug containing and preparation method thereof |
| CN109847055A (en) * | 2018-12-29 | 2019-06-07 | 济南秦鲁药业科技有限公司 | Medical scar plaster and preparation method thereof |
| CN110917179A (en) * | 2019-12-19 | 2020-03-27 | 温州医科大学附属第一医院 | Scar-resistant silicone gel patch and preparation method thereof |
| CN110917179B (en) * | 2019-12-19 | 2021-04-27 | 温州医科大学附属第一医院 | Scar-resistant silicone gel patch and preparation method thereof |
| CN111481347A (en) * | 2020-04-09 | 2020-08-04 | 苏州汇涵医用科技发展有限公司 | Silica gel scar plaster and preparation method thereof |
| CN114432273A (en) * | 2021-12-22 | 2022-05-06 | 德州昌诚新材料有限公司 | Preparation method of silica gel plaster |
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| C06 | Publication | ||
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Application publication date: 20151118 |