CN105028441A - Insecticidal and acaricidal composition, and application thereof - Google Patents
Insecticidal and acaricidal composition, and application thereof Download PDFInfo
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- CN105028441A CN105028441A CN201510405414.7A CN201510405414A CN105028441A CN 105028441 A CN105028441 A CN 105028441A CN 201510405414 A CN201510405414 A CN 201510405414A CN 105028441 A CN105028441 A CN 105028441A
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Abstract
The present invention discloses an insecticidal and acaricidal composition, and application thereof, relating to the technical field of pesticide compounding. The insecticidal and acaricidal composition of the invention comprises active ingredients A and B. The active ingredient A is bifenazate, and the active ingredient B is one or more of phenylpyrazole insecticides: fipronil, butene-fipronil, and ethiprole. The weight ratio between the active ingredients A and B is 1:30-40:1, preferably 1:20-20:1. The compounded agent has a reasonable compounding ratio, a significant synergistic effect, and especially an excellent effect on carmine spider mites, two-spotted spider mites and the others of agricultural mites, so as to effectively reduce the amount of each applied single agent, to achieve the purpose of delaying the drug resistance and lowering cost, and to achieve an obvious value of application and promotion.
Description
Technical field
The present invention relates to a kind of insecticide acaricide composition and application thereof, refer to a kind of insecticide acaricide composition and the application thereof that contain active ingredient Bifenazate and Phenylpyrazole insecticides especially, belong to technical field of pesticide combination.
Background technology
In the real process of agricultural production, chemical control remains the most effective means of pest control, but continuing and a large amount of uses due to chemical insecticide, pest resistance to insecticide problem is constantly given prominence to.And the insect easily developed immunity to drugs normally large, the obvious insect of generation overlap of breeding amount.As plant hopper, aphid, two spotted spider mite, diamond-back moth etc.
Bifenazate (bifenazate), chemical molecular formula C
17h
20n
2o
3.Bifenazate is a kind of γ-aminobutyric acid (GABA) antagonist, mainly prevents and treats active stage tetranychid, and quick-acting is good, if to young mite with to become mite effective, to some other mite classes, especially have ovicidal action to Tetranychus urticae.Laboratory research shows, Bifenazate does not have negative effect to predatism benefit mite; To the low (LD of mammalian toxicity
50for 5000mg/kg); Lasting period short (DT in the environment
50<1d).The Bifenazate sold in the market is the suspending agent of 480 grams per liters, is mainly used in control apple tree two spotted spider mite.As a kind of new hydrazine ester class specialty miticide, it is high that Bifenazate in use also exists use cost, the risk that resistance risk increases gradually, the defect that lasting period is short, and it is rationally mixed with dissimilar miticide, for fully effectively promoting Bifenazate, extending its service life and there is important function
Phenylpyrazole insecticides belongs to broad spectrum insecticide miticide, tag, stomach toxicity, interior suction, as ethiprole, capillary etc., with existing insecticide without cross resistance.
Ethiprole (Fipronil);, Frontline clear also known as: Fei Poluoni, fluorine worm, chemical name: (RS)-5-amino-1-(chloro-a of 2,6-bis-; a, a-trifluoro-p-tolyl)-4-trifluoromethyl sulfinyl pyrazole-3-nitrile.Ethiprole is that a kind of Phenylpyrazole insecticides, insecticidal spectrum are wide, to insect based on stomach poison function, have concurrently and tag and certain systemic action, its mechanism of action is the chloride metabolism hindering insect γ-aminobutyric acid to control, therefore very high insecticidal activity is had, to crop without poisoning to important pests such as aphid, leafhopper, plant hopper, lepidopterous larvae, fly class and coleopteras.This medicament can impose on soil, also can foliar spray.Imposing on soil can effectively chrysomelid, the wireworm of control of maize root and cutworm.During foliage spray, all have high-level preventive effect to diamond-back moth, imported cabbageworm, rice thrips etc., and the lasting period is long.
Butene-fipronil (butene-fipronil) this compound is the Phenylpyrazole insecticides formulated by Ruize Farm-Chemicals Co., Ltd., Dalian.Chemical name: 5-(N-2-methyl-2-acrylic) amino-1-(2,6-dichlor-4-trifluoromethyl phenyl)-4-trifluoromethyl sulfinyl pyrazole-3-nitrile.Butene-fipronil has higher activity to various pests such as cabbage caterpillar, diamond-back moth, snout moth's larva, mythimna separata, brown planthopper, chrysomelid, thrips, particularly manifests and Frontline equally valid the activity of paddy rice, vegetable-crop pest-insect, and to fish low toxicity.
Second worm nitrile, English general ethiprole by name, molecular formula is: C
13h
9cl
2f
3n
4oS; chemical name: 1-(2; 6-dichlor-4-trifluoromethyl phenyl)-3-cyano group-4-ethylsulfinyl-5-amino-pyrazol; second worm nitrile (Ethiprole) is the Insecticidal and acaricidal agent developed by rhone-poulenc discovery, Beyer Co., Ltd; belong to the second generation act under the low consumption of insecticide of GABA to multiple chewing type and sucking pest effective; can be used for seed treatment and foliar spray, the lasting period reaches 21-28d.Second worm nitrile is a kind of novel Insecticidal pyrazolines, and insecticidal spectrum is wide.Disturb chloride channel by γ-aminobutyric acid (GABA), thus destruction central nervous system (CNS) normal activity makes insect lethal.This medicine is more tight to the constraint comparison vertebrate of insect GABA chloride channel, thus provides very high selection toxicity.Its mechanism of action is different from the main insecticide kind such as pyrethroid, organic phosphor, carbamate, with the existing common insecticide of majority without interactivity.Therefore, it is the desirable kind of resistance management.
For the insect in control agricultural production and resistant insect, a kind of way be release new for the new component of existing kind without cross resistance.But the development cost of new active ingredient is high, and the construction cycle is long, usual cost billions of dollars, last more than 5 years, and once there is resistance, usually cause chemical control to lose efficacy, be forced to stop using or eliminate.And exploitation medicament all produces the speed of resistance usually less than insect.Other method, as crop structure adjustment, different agricultural chemicals rotations etc., in the process of practical operation, is difficult to really play obvious effect.
The composition of different cultivars carries out composite, is to prevent and treat the common way of resistant insect.Heterogeneity is carried out composite, according to the effect of practical application, judge certain composite be synergy, addition and or antagonism.Compound synergic is well filled a prescription, and owing to significantly improving actual control efficiency, reduces the usage amount of agricultural chemicals, thus has delayed the generation of pest resistance to insecticide greatly, is the important means of integrated control insect.
Summary of the invention
The technical problem to be solved in the present invention is to provide a kind of good disinsection effect, and Complex synergism is obvious, the insecticide acaricide composition that drug cost is low and application thereof.
For solving the problems of the technologies described above, the invention provides technical scheme as follows:
Insecticide acaricide composition of the present invention, comprises effective constituents A and B, and effective constituents A is Bifenazate, active ingredient B be Phenylpyrazole insecticides ethiprole, butene-fipronil, second worm nitrile one or more.Wherein, the weight ratio of described effective constituents A and active ingredient B is 1:30 ~ 40:1.Further, the weight ratio of effective constituents A and active ingredient B is 1:20 ~ 20:1; Further, the weight ratio of effective constituents A and active ingredient B is 1:10 ~ 10:1.
Also containing pesticidal preparations auxiliary element in insecticide acaricide composition of the present invention, to make the formulation being applicable to agriculturally using.Described pesticidal preparations auxiliary element is one or more in solvent, emulsifier, dispersant, stabilizing agent, antifreezing agent or wetting agent.
Insecticide acaricide composition of the present invention, according to the known method of those skilled in the art of the present technique, can be mixed with arbitrary formulation of applicable agricultural use, good formulation for can be wetting powder, aqueous emulsion, microemulsion, suspending agent, water-dispersible granules etc.
Insecticide acaricide composition of the present invention, can be applied to the pesticidal preparations of preparation control insect pest of the plant.Particularly be applied to the pesticidal preparations of the agriculture acarid of preparation control.Especially the pesticidal preparations of preparation control Tetranychus cinnabarinus, Tetranychus urticae is applied to.
Insecticide acaricide composition of the present invention can finished product preparation form provide, namely in composition, each material mixes, or the composition of composition also can provide with unit dose form, directly directly mix in bucket or tank before using, be then diluted to required concentration.
Insecticide acaricide composition of the present invention is applied to the method for prevention and elimination of disease and pests, and active principle A and B component are used with above-mentioned weight ratio, and it is used after can mixing in proportion, use in proportion simultaneously or use successively in proportion.Concrete method of application can be powder injection process, spray-on process, smog method, fumigating system and seed treatment and soil treatment, ultra low volume spraying, mixes fertilizer, spreads fertilizer over the fields, fills with root.Control nematode is preferred ditch spread, fill with root, the soil treatment such as to spread manuer in holes or leaching root, seed soaking.
Compared with prior art, beneficial effect of the present invention is: 1, compared with single dose, and composite have obvious synergistic function, improves control efficiency; 2, composition is made up of the active ingredient that two kinds of mechanism of action are different, and good disinsection effect, is conducive to overcoming and delay drug-fast generation; 3, medicament mixture decreases dosage, thus reduces cost and alleviate the pollution to environment.
The present invention has excellent control efficiency to the such as agriculture acarid such as Tetranychus cinnabarinus, Tetranychus urticae.
Embodiment
For making the technical problem to be solved in the present invention, technical scheme and advantage clearly, will be described in detail with specific embodiment below, but the present invention is limited to absolutely not these examples.The following stated is only the good embodiment of the present invention, only in order to explain the present invention, therefore can not be interpreted as the restriction to the scope of the claims of the present invention.It should be pointed out that all any amendments done within the spirit and principles in the present invention, equivalent replacement and improvement etc., all should be included within protection scope of the present invention.Therefore, the protection domain of patent of the present invention should be as the criterion with claims.
The combination of active principles of different agricultural chemicals is made agricultural chemicals, is current development novel pesticide and the one of preventing and treating agriculturally resistance germ effectively and efficiently mode.After the pestsides synthesis of different cultivars, usually show a large amount of three kinds of type of action: summation action, synergistic effect and antagonism.Compound synergic is well filled a prescription, and can significantly improve actual control efficiency, and reducing the usage amount of agricultural chemicals, thus contribute to delaying drug-fast generation speed, is the important means of integrated control damage by disease and insect.
The present composition comprises effective constituents A and B, and effective constituents A is Bifenazate, active ingredient B be Phenylpyrazole insecticides ethiprole, butene-fipronil, second worm nitrile one or more.Combine between them and have obvious synergistic function to pest control, and be not only the simple superposition of two kinds of pharmacy effects, this clearly can recognize from following test result.
In order to prevent and treat the Tetranychus cinnabarinus in agriculturally producing, inventor has carried out mutual composite synergy and has studied with the ethiprole of Phenylpyrazole insecticides, butene-fipronil, second worm nitrile with Bifenazate respectively.Test adopts Tetranychus cinnabarinus to be tested object, and concrete grammar is:
Indoor biometrics compound screening is tested:
Reagent agent: the former medicine of 95% Bifenazate, the former medicine of 97% ethiprole, 96% butene-fipronil, 95% second worm nitrile.
For examination worm source:
Tetranychus cinnabarinus: pick up from September, 2012 in experimental field, academy of agricultural sciences of Guangdong Province, raise the kidney bean seedling of indoor not contacted medicament, raising temperature is 27 ± 1 DEG C, relative moisture 60%-80%, and the photoperiod is 16:8h (L:D).
Test method:
Tetranychus cinnabarinus assay method: adopt the slide infusion process that FAO (1980) recommends, 2cm × 2cm two-sided tape is bonded at one end of slide, provoke into mite gently with little writing brush its back to be bonded on adhesive tape and (mite foot, antenna and mouthpart can not to be clung), sticky 4 row of every sheet, often row 10.The slide of sticky enough 40 two spotted spider mite is put into clean nontoxic large culture dish, and puts a moisturizing cotton balls moisturizing, add a cover under being placed on room temperature, place 2h, under binocular anatomical lens, check two spotted spider mite adhesion situation, reject dead and inactive individuality, statistics borer population alive, as test radix.The slide adding up quantity is immersed in the liquid of variable concentrations respectively, take out after jog 5s, unnecessary liquid is sucked with blotting paper, put into culture dish, a moisturizing cotton balls is put in ware, add a cover and be placed on that temperature is 25 ± 1 DEG C, relative moisture 75%, illumination L: D is in the incubator of 16: 8, under binocular anatomical lens, death condition is checked after 24h, mite body is touched with writing brush, the motionless person of chelicera is considered as death, select valid density according to investigation result, and establish the corresponding organic solvent process not containing medicament not do blank.3 repetitions are established in test.Data processing:
POLOPlus software is adopted to calculate toxicity regression formula.Calculating parameter comprises: slope b value and standard error, card square, degree of freedom, LC
50value and 95% confidence limit.
Co-toxicity evaluation method:
The lab screening of composite formula adopts the abundant co-toxicity coefficient method of Sun Yun:
Toxicity index (TI)=(LC of standard agent
50the LC of/reagent agent
50) × 100
The LC that the actual toxicity index of mixture (ATI)=medicament A is alone
50the LC that/medicament A with B is mixed
50) × 100
Theoretical toxicity index (TTI)=TI (A) × a+TI (the B) × b of mixture
A: represent the percentage composition of medicament A in mixture;
B: represent the percentage composition of medicament B in mixture.
Co-toxicity coefficient CTC=(the theoretical toxicity index TTI of the actual toxicity index ATI/ mixture of mixture) × 100
According to the regulation of the Institute for the Control of Agrochemicals of the Ministry of Agriculture,PRC, the criterion of mixture formula synergy is: co-toxicity coefficient is greater than 120 for synergistic effect; Co-toxicity coefficient 80-120 is summation action; Co-toxicity coefficient is less than 80, is antagonism.
The selection of optimum proportioning is with the co-toxicity coefficient of mixture and LC
50(or LD
50) value two indices weighs, i.e. higher the and LC of co-toxicity coefficient
50(or LD
50) value minimum (namely surveying toxicity index maximum).
The single dose of table 1 Bifenazate and ethiprole and mixture are to the toxicity test of Tetranychus cinnabarinus.
| Chemicals treatment | Proportioning | Slope S lope (SE) | LC 50(mg/L) | Co-toxicity coefficient (CTC) |
| Bifenazate (A) | —— | 2.312(0.221) | 0.11 | ---- |
| Ethiprole (B1) | —— | 1.856(0.242) | 5.45 | ---- |
| A:B1 | 1:30 | 1.999(0.313) | 1.92 | 129.97 |
| A:B1 | 1:20 | 1.634(0.267) | 1.55 | 137.03 |
| A:B1 | 1:10 | 1.541(0.273) | 0.82 | 200.69 |
| A:B1 | 1:5 | 2.373(0.222) | 0.41 | 245.56 |
| A:B1 | 1:2 | 1.824(0.217) | 0.23 | 260.65 |
| A:B1 | 1:1 | 2.784(0.374) | 0.15 | 211.46 |
| A:B1 | 2:1 | 2.132(0.337) | 0.09 | 239.61 |
| A:B1 | 5:1 | 1.718(0.312) | 0.07 | 233.36 |
| A:B1 | 10:1 | 2.137(0.305) | 0.06 | 219.12 |
| A:B1 | 20:1 | 1.976(0.265) | 0.06 | 201.26 |
| A:B1 | 30:1 | 2.023(0.243) | 0.08 | 212.91 |
| A:B1 | 40:1 | 1.345(0.235) | 0.07 | 162.27 |
Toxicity Determination result shows, within the scope of weight ratio 1:30-40:1, Bifenazate and ethiprole mixture, its co-toxicity coefficient is all greater than 120, all shows synergistic effect, is wherein within the scope of 1:20 ~ 20:1 at Bifenazate and ethiprole weight ratio, show as more obvious synergistic effect, the effectively agriculture acarid of control can be reached, reduce the object of single dose consumption, there is extremely strong Development volue.Weight ratio is within the scope of 1:10 ~ 10:1, Bifenazate and Firponil compounded, and synergistic effect is remarkable.
The single dose of table 2 Bifenazate and butene-fipronil and mixture are to the toxicity test of Tetranychus cinnabarinus
| Chemicals treatment | Proportioning | Slope S lope (SE) | LC 50(mg/L) | Co-toxicity coefficient (CTC) |
| Bifenazate (A) | —— | 2.312(0.221) | 0.11 | ---- |
| Butene-fipronil (B2) | —— | 2.236(0.221) | 3.25 | ---- |
| A:B2 | 1:30 | 1.889(0.324) | 1.53 | 125.23 |
| A:B2 | 1:20 | 1.724(0.234) | 1.11 | 152.43 |
| A:B2 | 1:10 | 1.345(0.273) | 0.67 | 205.60 |
| A:B2 | 1:5 | 2.214(0.231) | 0.45 | 200.89 |
| A:B2 | 1:2 | 1.824(0.213) | 0.24 | 235.20 |
| A:B2 | 1:1 | 2.112(0.324) | 0.15 | 206.05 |
| A:B2 | 2:1 | 2.332(0.337) | 0.1 | 212.80 |
| A:B2 | 5:1 | 1.876(0.242) | 0.08 | 202.82 |
| A:B2 | 10:1 | 2.117(0.335) | 0.06 | 218.52 |
| A:B2 | 20:1 | 1.346(0.265) | 0.06 | 200.99 |
| A:B2 | 30:1 | 2.134(0.251) | 0.08 | 212.76 |
| A:B2 | 40:1 | 1.878(0.248) | 0.06 | 189.23 |
Toxicity Determination result shows, within the scope of weight ratio 1:30-40:1, the butene-fipronil mixture of Bifenazate and Phenylpyrazole insecticides, its co-toxicity coefficient is all greater than 120, all shows synergistic effect, is wherein within the scope of 1:20 ~ 20:1 at Bifenazate and butene-fipronil weight ratio, show as more obvious synergistic effect, the effectively agriculture acarid of control can be reached, reduce the object of single dose consumption, there is extremely strong Development volue.Weight ratio is within the scope of 1:10 ~ 10:1, Bifenazate and butene-fipronil composite, synergistic effect is remarkable.
The single dose of table 3 Bifenazate and second worm nitrile and mixture are to the toxicity test of Tetranychus cinnabarinus
| Chemicals treatment | Proportioning | Slope S lope (SE) | LC 50(mg/L) | Co-toxicity coefficient (CTC) |
| Bifenazate (A) | —— | 2.312(0.221) | 0.11 | ---- |
| Second worm nitrile (B3) | —— | 2.131(0.235) | 7.65 | ---- |
| A:B3 | 1:30 | 2.019(0.314) | 2.23 | 128.39 |
| A:B3 | 1:20 | 1.889(0.235) | 1.29 | 184.68 |
| A:B3 | 1:10 | 2.321(0.173) | 0.86 | 208.61 |
| A:B3 | 1:5 | 2.224(0.132) | 0.45 | 235.09 |
| A:B3 | 1:2 | 1.762(0.123) | 0.29 | 212.32 |
| A:B3 | 1:1 | 2.002(0.214) | 0.15 | 213.85 |
| A:B3 | 2:1 | 2.112(0.312) | 0.1 | 216.88 |
| A:B3 | 5:1 | 1.564(0.231) | 0.07 | 234.03 |
| A:B3 | 10:1 | 2.431(0.331) | 0.06 | 219.37 |
| A:B3 | 20:1 | 2.321(0.173) | 0.06 | 201.38 |
| A:B3 | 30:1 | 1.324(0.111) | 0.05 | 230.83 |
| A:B3 | 40:1 | 1.558(0.221) | 0.08 | 142.02 |
Toxicity Determination result shows, within the scope of weight ratio 1:30-40:1, particularly within the scope of 1:20-20:1, Bifenazate with second worm nitrile is composite has obvious synergistic effect to Tetranychus cinnabarinus, control efficiency excellence and be better than single dose kind.Weight ratio is within the scope of 1:10 ~ 10:1, Bifenazate and second worm nitrile composite, synergistic effect is remarkable.
Insecticide acaricide composition of the present invention can be prepared into any one formulation of applicable agricultural use by known method, reasonable formulation is wetting powder, aqueous emulsion, microemulsion, suspending agent, water dispersible granules.In all formulas, percentage is all weight percentage.The processing technology of the various formulation of the present composition is prior art, can change to some extent according to different situations.
For making the technical problem to be solved in the present invention, technical scheme and advantage clearly, within the scope of weight ratio 1:30-40:1, build Bifenazate and second worm nitrile is composite, Bifenazate and Firponil compounded, Bifenazate and the composite embodiment of butene-fipronil, be described in detail, but the present invention is limited to absolutely not these examples.
In addition, inventor also found through experiments, Bifenazate and chlorfenapyr is composite also certain synergistic effect.But the effect that Bifenazate is composite with second worm nitrile, Bifenazate and Firponil compounded, Bifenazate and butene-fipronil are composite than Bifenazate and chlorfenapyr composite more outstanding.Therefore, in order to this problem is described, in the proportion identical with embodiment, Bifenazate and the composite comparative example of chlorfenapyr is constructed.Be described in detail.It should be pointed out that Bifenazate and second worm nitrile is composite, Bifenazate and Firponil compounded, Bifenazate and the composite Be very effective of butene-fipronil is better than Bifenazate and chlorfenapyr is composite, be not only confined in limited comparative example.
Below in conjunction with embodiment, content of the present invention is described further.
Embodiment 1:31% Bifenazate ethiprole suspending agent (1:30)
Bifenazate 1%, ethiprole 30%, agriculture breast 400
#5%, modified naphthalene sulfonate formaldehyde condensation products 1%, sodium lignin sulfonate 5%, silicone oil 0.5%, ethylene glycol 4%, xanthans 0.2%, Kathon CG 0.5%, deionized water supply 100%.Above raw material is prepared routinely the obtained 31% Bifenazate ethiprole suspending agent of method mixing of suspending agent.
Embodiment 2:31% Bifenazate butene-fipronil suspending agent (1:30)
Bifenazate 1%, butene-fipronil 30%, agriculture breast 400
#5%, modified naphthalene sulfonate formaldehyde condensation products 1%, sodium lignin sulfonate 5%, silicone oil 0.5%, ethylene glycol 4%, xanthans 0.2%, Kathon CG 0.5%, deionized water supply 100%.Above raw material is prepared routinely the obtained 31% Bifenazate ethiprole suspending agent of method mixing of suspending agent.
Embodiment 3:31% Bifenazate second worm nitrile suspending agent (1:30)
Bifenazate 1%, second worm nitrile 30%, agriculture breast 400
#5%, modified naphthalene sulfonate formaldehyde condensation products 1%, sodium lignin sulfonate 5%, silicone oil 0.5%, ethylene glycol 4%, xanthans 0.2%, Kathon CG 0.5%, deionized water supply 100%.Above raw material is prepared routinely the obtained 31% Bifenazate ethiprole suspending agent of method mixing of suspending agent.
Comparative example 1:31% Bifenazate chlorfenapyr suspending agent (1:30)
Bifenazate 1%, chlorfenapyr 30%, agriculture breast 400
#5%, modified naphthalene sulfonate formaldehyde condensation products 1%, sodium lignin sulfonate 5%, silicone oil 0.5%, ethylene glycol 4%, xanthans 0.2%, Kathon CG 0.5%, deionized water supply 100%.Above raw material is prepared routinely the obtained 31% Bifenazate ethiprole suspending agent of method mixing of suspending agent.
Embodiment 4:24% Bifenazate ethiprole water dispersible granules (1:23)
Bifenazate 1%, ethiprole 23%, lauryl sodium sulfate 1%, sodium lignin sulfonate 6%, anhydrous sodium sulfate 3%, kaolin supply 100%.Above raw material is prepared routinely the obtained 24% Bifenazate ethiprole water dispersible granules of method mixing of water dispersible granules.
Embodiment 5:24% Bifenazate butene-fipronil water dispersible granules (1:23)
Bifenazate 1%, butene-fipronil 23%, lauryl sodium sulfate 1%, sodium lignin sulfonate 6%, anhydrous sodium sulfate 3%, kaolin supply 100%.Above raw material is prepared routinely the obtained 24% Bifenazate ethiprole water dispersible granules of method mixing of water dispersible granules.
Embodiment 6:24% Bifenazate second worm nitrile water dispersible granules (1:23)
Bifenazate 1%, second worm nitrile 23%, lauryl sodium sulfate 1%, sodium lignin sulfonate 6%, anhydrous sodium sulfate 3%, kaolin supply 100%.Above raw material is prepared routinely the obtained 24% Bifenazate ethiprole water dispersible granules of method mixing of water dispersible granules.
Comparative example 2:24% Bifenazate chlorfenapyr water dispersible granules (1:23)
Bifenazate 1%, chlorfenapyr 23%, lauryl sodium sulfate 1%, sodium lignin sulfonate 6%, anhydrous sodium sulfate 3%, kaolin supply 100%.Above raw material is prepared routinely the obtained 24% Bifenazate ethiprole water dispersible granules of method mixing of water dispersible granules.
Embodiment 7:32% Bifenazate ethiprole dry suspending agent (1:15)
Bifenazate 2%, ethiprole 30%, modified naphthalene sulfonate formaldehyde condensation products 2%, sodium lignin sulfonate 8%, talcum powder supply 100%.Above raw material is prepared routinely the obtained 32% Bifenazate ethiprole dry suspending agent of method mixing of dry suspending agent.
Embodiment 8:32% Bifenazate butene-fipronil dry suspending agent (1:15)
Bifenazate 2%, butene-fipronil 30%, modified naphthalene sulfonate formaldehyde condensation products 2%, sodium lignin sulfonate 8%, talcum powder supply 100%.Above raw material is prepared routinely the obtained 32% Bifenazate butene-fipronil dry suspending agent of method mixing of dry suspending agent.
Embodiment 9:32% Bifenazate second worm nitrile dry suspending agent (1:15)
Bifenazate 2%, second worm nitrile 30%, modified naphthalene sulfonate formaldehyde condensation products 2%, sodium lignin sulfonate 8%, talcum powder supply 100%.Above raw material is prepared routinely the obtained 32% Bifenazate second worm nitrile dry suspending agent of method mixing of dry suspending agent.
Comparative example 3:32% Bifenazate chlorfenapyr dry suspending agent (1:15)
Bifenazate 2%, chlorfenapyr 30%, modified naphthalene sulfonate formaldehyde condensation products 22%, sodium lignin sulfonate 58%, talcum powder supply 100%.Above raw material is prepared routinely the obtained 32% Bifenazate chlorfenapyr dry suspending agent of method mixing of dry suspending agent.
Embodiment 10:26% Bifenazate ethiprole suspending agent (1:5.5)
Bifenazate 4%, ethiprole 22%, agriculture breast 400
#5%, modified naphthalene sulfonate formaldehyde condensation products 1%, sodium lignin sulfonate 5%, silicone oil 0.5%, ethylene glycol 4%, xanthans 0.2%, Kathon CG 0.5%, deionized water supply 100%.Above raw material is prepared routinely the obtained 26% Bifenazate ethiprole suspending agent of method mixing of suspending agent.
Embodiment 11:26% Bifenazate butene-fipronil suspending agent (1:5.5)
Bifenazate 4%, butene-fipronil 22%, agriculture breast 400
#5%, modified naphthalene sulfonate formaldehyde condensation products 1%, sodium lignin sulfonate 5%, silicone oil 0.5%, ethylene glycol 4%, xanthans 0.2%, Kathon CG 0.5%, deionized water supply 100%.Above raw material is prepared routinely the obtained 26% Bifenazate butene-fipronil suspending agent of method mixing of suspending agent.
Embodiment 12:26% Bifenazate second worm nitrile suspending agent (1:5.5)
Bifenazate 4%, second worm nitrile 22%, agriculture breast 400
#5%, modified naphthalene sulfonate formaldehyde condensation products 1%, sodium lignin sulfonate 5%, silicone oil 0.5%, ethylene glycol 4%, xanthans 0.2%, Kathon CG 0.5%, deionized water supply 100%.Above raw material is prepared routinely the obtained 26% Bifenazate second worm nitrile suspending agent of method mixing of suspending agent.
Comparative example 4:26% Bifenazate chlorfenapyr suspending agent (1:5.5)
Bifenazate 4%, chlorfenapyr 22%, agriculture breast 400
#5%, modified naphthalene sulfonate formaldehyde condensation products 1%, sodium lignin sulfonate 5%, silicone oil 0.5%, ethylene glycol 4%, xanthans 0.2%, Kathon CG 0.5%, deionized water supply 100%.Above raw material is prepared routinely the obtained 26% Bifenazate chlorfenapyr suspending agent of method mixing of suspending agent.
Embodiment 13:20% Bifenazate ethiprole wetting powder (1:1)
Bifenazate 10%, ethiprole 10%, lauryl sodium sulfate 2%, sodium lignin sulfonate naphthalenesulfonate formaldehyde condensation compound 6%, kaolin supply 100%.Above raw material is prepared routinely the method mixing of wetting powder, be crushed to certain fineness, then through being mixed into product, obtain 20% Bifenazate ethiprole wetting powder.
Embodiment 14:20% Bifenazate butene-fipronil wetting powder (1:1)
Bifenazate 10%, butene-fipronil 10%, lauryl sodium sulfate 2%, sodium lignin sulfonate naphthalenesulfonate formaldehyde condensation compound 6%, kaolin supply 100%.Above raw material is prepared routinely the method mixing of wetting powder, be crushed to certain fineness, then through being mixed into product, obtain 20% Bifenazate butene-fipronil wetting powder.
Embodiment 15:20% Bifenazate second worm nitrile wetting powder (1:1)
Bifenazate 10%, second worm nitrile 10%, lauryl sodium sulfate 2%, sodium lignin sulfonate naphthalenesulfonate formaldehyde condensation compound 6%, kaolin supply 100%.Above raw material is prepared routinely the method mixing of wetting powder, be crushed to certain fineness, then through being mixed into product, obtain 20% Bifenazate second worm nitrile wetting powder.
Comparative example 5:20% Bifenazate chlorfenapyr wetting powder (1:1)
Bifenazate 10%, chlorfenapyr 10%, lauryl sodium sulfate 2%, sodium lignin sulfonate naphthalenesulfonate formaldehyde condensation compound 6%, kaolin supply 100%.Above raw material is prepared routinely the method mixing of wetting powder, be crushed to certain fineness, then through being mixed into product, obtain 20% Bifenazate chlorfenapyr wetting powder.
Embodiment 16:21% Bifenazate ethiprole water dispersible granules (9.5:1)
Bifenazate 19%, ethiprole 2%, lauryl sodium sulfate 1%, sodium lignin sulfonate 6%, anhydrous sodium sulfate 3%, kaolin supply 100%.Above raw material is prepared routinely, obtains 21% Bifenazate ethiprole water dispersible granules (9.5:1).
Embodiment 17:16% Bifenazate butene-fipronil microemulsion (15:1)
Bifenazate 16%, butene-fipronil 1%, calcium dodecyl benzene sulfonate 5%, styrylphenol polyoxyethylene ether 6%, fatty alcohol-polyoxyethylene ether 4%, cyclohexanone 5%, trimethylbenzene 15% deionized water supply 100%.Above raw material is prepared routinely the obtained 16% Bifenazate butene-fipronil microemulsion of method mixing of microemulsion.
Embodiment 18:21% Bifenazate butene-fipronil aqueous emulsion (20:1)
Bifenazate 20%, butene-fipronil 1%, calcium dodecyl benzene sulfonate 5%, styrylphenol polyoxyethylene ether 6%, fatty alcohol-polyoxyethylene ether 4%, cyclohexanone 5%, trimethylbenzene 15% deionized water supply 100%.Above raw material is prepared routinely the obtained 21% Bifenazate butene-fipronil aqueous emulsion of method mixing of aqueous emulsion.
Embodiment 19:21% Bifenazate ethiprole emulsion in water (20:1)
Bifenazate 20%, second worm nitrile 1%, isopropyl alcohol 4%, cyclohexanone 12%, calcium dodecyl benzene sulfonate 2%, phenethyl phenol polyethenoxy ether 4%, ethylene glycol 4%, deionized water supply 100%.Above raw material is prepared routinely the obtained 21% Bifenazate ethiprole emulsion in water of method mixing of aqueous emulsion.
Comparative example 6:21% Bifenazate chlorfenapyr aqueous emulsion (20:1)
Bifenazate 20%, chlorfenapyr 1%, isopropyl alcohol 4%, cyclohexanone 12%, calcium dodecyl benzene sulfonate 2%, phenethyl phenol polyethenoxy ether 4%, ethylene glycol 4%, deionized water supply 100%.Above raw material is prepared routinely the obtained 21% Bifenazate chlorfenapyr aqueous emulsion of method mixing of aqueous emulsion.
Embodiment 20:26% Bifenazate ethiprole water dispersible granules (25:1)
Bifenazate 25%, ethiprole 1%, lauryl sodium sulfate 1%, sodium lignin sulfonate 6%, anhydrous sodium sulfate 3%, kaolin supply 100%.Above raw material is prepared routinely the obtained 26% Bifenazate ethiprole water dispersible granules of method mixing of water dispersible granules.
Embodiment 21:16.4% Bifenazate ethiprole suspending agent (40:1)
Bifenazate 16%, ethiprole 0.4%, agriculture breast 400
#5%, modified naphthalene sulfonate formaldehyde condensation products 1%, sodium lignin sulfonate 5%, silicone oil 0.5%, ethylene glycol 4%, xanthans 0.2%, Kathon CG 0.5%, deionized water supply 100%.Above raw material is prepared routinely the obtained 16.4% Bifenazate ethiprole suspending agent of method mixing of suspending agent.
Embodiment 22:16.4% Bifenazate butene-fipronil suspending agent (40:1)
Bifenazate 16%, butene-fipronil 0.4%, agriculture breast 400
#5%, modified naphthalene sulfonate formaldehyde condensation products 1%, sodium lignin sulfonate 5%, silicone oil 0.5%, ethylene glycol 4%, xanthans 0.2%, Kathon CG 0.5%, deionized water supply 100%.Above raw material is prepared routinely the obtained 16.4% Bifenazate butene-fipronil suspending agent of method mixing of suspending agent.
Embodiment 23:16.4% Bifenazate second worm nitrile suspending agent (40:1)
Bifenazate 16%, second worm nitrile 0.4%, agriculture breast 400
#5%, modified naphthalene sulfonate formaldehyde condensation products 1%, sodium lignin sulfonate 5%, silicone oil 0.5%, ethylene glycol 4%, xanthans 0.2%, Kathon CG 0.5%, deionized water supply 100%.Above raw material is prepared routinely the obtained 16.4% Bifenazate second worm nitrile suspending agent of method mixing of suspending agent.
Comparative example 7:16.4% Bifenazate chlorfenapyr suspending agent (40:1)
Bifenazate 16%, chlorfenapyr 0.4%, agriculture breast 400
#5%, modified naphthalene sulfonate formaldehyde condensation products 1%, sodium lignin sulfonate 5%, silicone oil 0.5%, ethylene glycol 4%, xanthans 0.2%, Kathon CG 0.5%, deionized water supply 100%.Above raw material is prepared routinely the obtained 16.4% Bifenazate chlorfenapyr suspending agent of method mixing of suspending agent.
Ethiprole in above embodiment, butene-fipronil, second worm nitrile can be replaced mutually, to form new embodiment.No longer carry out this repeating to enumerate, it should be pointed out that for those skilled in the art, under the prerequisite not departing from principle of the present invention, can also make some improvements and modifications, these improvements and modifications also should be considered as protection scope of the present invention.
Land for growing field crops application test: field Tetranychus cinnabarinus and Tetranychus urticae test
Contrast experiment is carried out by embodiment and 43% Bifenazate SC, 50g/L ethiprole SC, 5% butene-fipronil EC, 9.7% second worm nitrile SC single dose.With Tetranychus cinnabarinus and Tetranychus urticae for experimental subjects, there is with insect pest the phase of containing most and carry out dispenser, dispenser 1 time altogether, before dispenser, after dispenser 3 days, 7 days, within 21 days, investigate mite population respectively and calculate control efficiency.Control efficiency calculates as follows:
PT in formula
0: before dispenser, PT
1: after dispenser, PT: chemicals treatment district, CK: blank district.
Field efficacy the results are shown in Table 4-10:
Table 4 Bifenazate and the Firponil compounded field trial to Tetranychus cinnabarinus (Mianyang San Tai) measurement result
Note: lowercase alphabet is shown in significant difference in 0.05 level, capitalization represents significant difference in 0.01 level.
Table 5 Bifenazate and the Firponil compounded field trial to Tetranychus urticae (Mianyang San Tai) measurement result
Note: lowercase alphabet is shown in significant difference in 0.05 level, capitalization represents significant difference in 0.01 level.
Field control effectiveness test result can be found out, Bifenazate and Firponil compoundedly have obvious synergistic effect to insect pest of the plant, tests its control efficiency to Tetranychus cinnabarinus and Tetranychus urticae.In the scope of weight ratio 1:30-40:1, Bifenazate and Firponil compounded there is synergistic effect; In the scope of particularly 1:20-20:1, Bifenazate and Firponil compounded there is obvious synergistic effect; In the scope of especially 1:15-15:1, Bifenazate and Firponil compounded there is obvious synergistic effect.Because length is limited, be not repeated.
Table 6 Bifenazate and the composite field trial to Tetranychus cinnabarinus of butene-fipronil (Mianyang San Tai) measurement result
Note: lowercase alphabet is shown in significant difference in 0.05 level, capitalization represents significant difference in 0.01 level.
Table 7 Bifenazate and the composite field trial to Tetranychus urticae of butene-fipronil (Mianyang San Tai) measurement result
Note: lowercase alphabet is shown in significant difference in 0.05 level, capitalization represents significant difference in 0.01 level
Inventor finds Bifenazate and butene-fipronil is composite has obvious synergistic effect to insect pest of the plant, tests its control efficiency to Tetranychus cinnabarinus and Tetranychus urticae.Within the scope of weight ratio 1:30-40:1, Bifenazate and butene-fipronil is composite has obvious synergistic effect; In the scope of particularly 1:20-20:1, Bifenazate and butene-fipronil is composite has obvious synergistic effect; Bifenazate and butene-fipronil is composite has obvious synergistic effect in the scope of especially 1:15-15:1.Because length is limited, be not repeated.
Table 8 Bifenazate and the composite field trial to Tetranychus cinnabarinus of second worm nitrile (Mianyang San Tai) measurement result
Note: lowercase alphabet is shown in significant difference in 0.05 level, capitalization represents significant difference in 0.01 level.
Table 9 Bifenazate and the composite field trial to Tetranychus urticae of second worm nitrile (Mianyang San Tai) measurement result
Note: lowercase alphabet is shown in significant difference in 0.05 level, capitalization represents significant difference in 0.01 level.
Inventor finds Bifenazate and second worm nitrile is composite has obvious synergistic effect to insect pest of the plant, tests its control efficiency to Tetranychus cinnabarinus and Tetranychus urticae.Within the scope of weight ratio 1:30-40:1, Bifenazate and second worm nitrile is composite has obvious synergistic effect; Bifenazate and second worm nitrile is composite has obvious synergistic effect in the scope of Bifenazate and second worm nitrile is composite has obvious synergistic effect in the scope of particularly 1:20-20:1, especially 1:15-15:1.Because length is limited, be not repeated.
Table 10 embodiment and comparative example are to the control efficiency comparative result (Pixian County, Chengdu) of Tetranychus cinnabarinus
Note: lowercase alphabet is shown in significant difference in 0.05 level, capitalization represents significant difference in 0.01 level.
Inventor find Bifenazate and chlorfenapyr composite, within the scope of weight ratio 1:30-40:1, also there is certain Complex synergism.Because length limit, do not enumerate, only carry out preventive effect contrast with the representational comparative example of most and embodiment, as table 10 field efficacy result shows, (particularly within the scope of 1:20-20:1) Bifenazate and Firponil compounded within the scope of weight ratio 1:30-40:1, Bifenazate and butene-fipronil is composite, Bifenazate and second worm nitrile synergistic effect obvious, and than Bifenazate and the composite control efficiency to agriculture acarid of chlorfenapyr more outstanding, reach significance level.
The above is the preferred embodiment of the present invention; it should be pointed out that for those skilled in the art, under the prerequisite not departing from principle of the present invention; can also make some improvements and modifications, these improvements and modifications also should be considered as protection scope of the present invention.
Claims (9)
1. an insecticide acaricide composition, is characterized in that, comprises effective constituents A and B, and effective constituents A is Bifenazate, active ingredient B be Phenylpyrazole insecticides ethiprole, butene-fipronil, second worm nitrile one or more.
2. insecticide acaricide composition according to claim 1, is characterized in that, the weight ratio of described effective constituents A and active ingredient B is 1:30 ~ 40:1.
3. insecticide acaricide composition according to claim 2, is characterized in that, the weight ratio of described effective constituents A and active ingredient B is 1:20 ~ 20:1.
4. the insecticide acaricide composition according to claim arbitrary in claims 1 to 3, is characterized in that, also containing pesticidal preparations auxiliary element in described insecticide acaricide composition, to make the formulation being applicable to agriculturally using.
5. insecticide acaricide composition according to claim 4, its feature exists, and described pesticidal preparations auxiliary element is one or more in solvent, emulsifier, dispersant, stabilizing agent, antifreezing agent or wetting agent.
6. insecticide acaricide composition according to claim 4, is characterized in that, the formulation of described insecticide acaricide composition is wetting powder, aqueous emulsion, microemulsion, suspending agent, water dispersion granule.
7. the application of insecticide acaricide composition according to claim 1, is characterized in that, for the preparation of the application in the pesticidal preparations of control insect pest of the plant.
8. the application of insecticide acaricide composition according to claim 7, is characterized in that, for the preparation of the pesticidal preparations of the agriculture acarid of control.
9. the application of the insecticide acaricide composition described in claim 7 or 8, is characterized in that, for the preparation of the application in the pesticidal preparations of control Tetranychus cinnabarinus, Tetranychus urticae.
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