CN105012602B - Treat the Chinese medicine composition of viral respiratory tract disease of fowl - Google Patents

Treat the Chinese medicine composition of viral respiratory tract disease of fowl Download PDF

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CN105012602B
CN105012602B CN201510471826.0A CN201510471826A CN105012602B CN 105012602 B CN105012602 B CN 105012602B CN 201510471826 A CN201510471826 A CN 201510471826A CN 105012602 B CN105012602 B CN 105012602B
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CN105012602A (en
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常功
王景仙
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Zhengzhou Nublion Biotechnology Co ltd
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Abstract

The invention belongs to veterinary drug technical fields, and in particular to a kind of Chinese medicine composition for treating viral respiratory tract disease of fowl is made of the raw material for including following parts by weight:80 110 parts of wilsonii, 70 90 parts of Radix Astragali, 80 100 parts of honeysuckle, 180 200 parts of Radix Isatidis, 60 80 parts of radix scutellariae, 60 80 parts of radix bupleuri, 80 90 parts of Chinese ephedra, 40 60 parts of semen armeniacae amarae, 50 60 parts of subprostrate sophora, 80 100 parts of Chinese violet, 40 50 parts of moxibustion hay, 60 70 parts of prepared RHIZOMA PINELLIZE without adju-vant, 60 70 parts of PORIA ALBA, 100 110 parts of dried orange peel, 40 65 parts of Rabdosia rubescens and continuous numb 30 50 parts of rhizome of cyrtomium.The Chinese medicine composition of present invention treatment viral respiratory tract disease of fowl belongs to pure Chinese medicinal preparation, has no toxic side effect, and avoids when using antibiotic the liver reaction of renal toxicity caused by poultry, while also avoid the immune response of vaccine.

Description

Treat the Chinese medicine composition of viral respiratory tract disease of fowl
Technical field
The invention belongs to veterinary drug technical fields, and in particular to a kind of Chinese traditional medicine composition for treating viral respiratory tract disease of fowl Object.
Background technology
Chicken respiratory tract disease shows as high fever more, and the blue bleeding of cockscomb, fried hair flock together, and the symptoms such as stench mucus are flowed in mouth, Tracheal bronchus white or yellow fester block, and expiratory dyspnea, which dies of exhaustion, dies, and propagate soon, loss is big.Mycoplasma is ten thousand diseases Source, a variety of mycoplasma gallinarums do not reach purification standard, mycoplasma vertical transmission, and the chick for being easily infects chronic respiratory tract disease It just easily sends out, so that the hypoimmunity of chick, easily occurs virus infection, and then generation breathing problem.In addition birds One of specific airbag structure and the multiple inducement of respiratory tract, the respiratory system of chicken from nose to lung, to abdominal viscera, to The open to the outside world system of bone and linked groups is all associated with airbag structure.Such structure is prone to respiratory tract infection, and The infection of respiratory system is easy to diffuse to chicken abdominal viscera even whole body.
In today of the breeding scale fast development of poultry, the control method of virus type respiratory tract, mainly by vaccine It is immune, such as ND IB, IBD, AI, but in recent years since the continuous dosage of these vaccine strains uses and mycotoxin Harm so that the immunosupress of poultry is on the rise, and enough antibody cannot be generated after all multi-vaccine uses, so as to make house The viral respiratory of fowl is multiple.
When using Lasota seedlings or H120 is immune, these vaccine strains lived replicate in chicken tracheal mucosa, cause gas Pipe mucosa cells come off, and the respiratory response of " invertibity ", 3-5 days clear-cutting forestlands after healthy chicken occurs occur.But meat sold on the market Chicken usually secondary breathing problem.Poultry IBD's is immune, is one of the reason of causing fowl respiratory disease, because of fowl method Family name's capsule vaccine virulence is stronger, and stimulation is larger, is also easy to produce immunosupress, and the antibody for especially influencing ND, IB generates, so that one The respiratory diseases such as a little chicken houses that strong malicious bursa of fabricius vaccine is used for a long time, NDIB are multiple.
Invention content
To overcome drawbacks described above, present invention aims at provide a kind of Chinese medicine group for treating viral respiratory tract disease of fowl Object is closed, pure Chinese medicine compatibility do not injure liver kidney, avoids when using antibiotic the liver reaction of renal toxicity caused by poultry, The immune response of vaccine is also avoided simultaneously.
To achieve the above object, the present invention adopts the following technical scheme that:
A kind of Chinese medicine composition for treating viral respiratory tract disease of fowl, is prepared from the following raw materials in parts by weight:
80-110 parts of wilsonii, 70-90 parts of Radix Astragali, 80-100 parts of honeysuckle, 180-200 parts of Radix Isatidis, radix scutellariae 60-80 Part, 60-80 parts of radix bupleuri, 80-90 parts of Chinese ephedra, 40-60 parts of semen armeniacae amarae, 50-60 parts of subprostrate sophora, 80-100 parts of Chinese violet, moxibustion are sweet 40-50 parts careless, 60-70 parts of prepared RHIZOMA PINELLIZE without adju-vant, 60-70 parts of PORIA ALBA, 100-110 parts of dried orange peel, 40-65 parts of Rabdosia rubescens and continuous numb rhizome of cyrtomium 30-50 parts.
According to the Chinese medicine composition of above-mentioned treatment viral respiratory tract disease of fowl, by the raw material system of following parts by weight Into:
82 parts of wilsonii, 70 parts of Radix Astragali, 80 parts of honeysuckle, 180 parts of Radix Isatidis, 64 parts of radix scutellariae, 64 parts of radix bupleuri, Chinese ephedra 80 Part, 40 parts of semen armeniacae amarae, 52 parts of subprostrate sophora, 80 parts of Chinese violet, 40 parts of moxibustion Radix Glycyrrhizae, 70 parts of prepared RHIZOMA PINELLIZE without adju-vant, 60 parts of PORIA ALBA, dried orange peel 100 parts, 50 parts of Rabdosia rubescens, continuous numb 30 parts of rhizome of cyrtomium.
According to the Chinese medicine composition of above-mentioned treatment viral respiratory tract disease of fowl, decoction preparation method includes following step Suddenly:Each bulk pharmaceutical chemicals of above-mentioned parts by weight are sliced, mixing is poured into pot, the water of 8-15 times of volume of addition, immersion 25~ 40min decocts 2~3 times, decocts 1~2h every time, and the decoction decocted every time mixes, filtered, sterilizing.
The pharmacological action of the various bulk pharmaceutical chemicals of the present invention:
Wilsonii:Pungent, slight bitter, temperature, returns spleen, kidney, the heart channel of Hang-Shaoyin;It replenishes qi to invigorate the spleen, tonifies the kidney to relieve mental strain, it is physically weak weary for the insufficiency of both the spleen and the kindey Power, loss of appetite, soreness of waist and knee joint, insomnia and dreamful sleep.
Radix Astragali:Sweet, warm, return lung, the spleen channel;Invigorating qi for strengthening superficies, diuretic and maintain drug, apocenosis, expelling pus and promoting granulation, for treatment deficiency of vital energy weak, food Few loose stool, the sinking of qi of middle-jiao, rush down prolapse of the anus for a long time, uterine bleeding of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy oedema, ulcer is difficult to burst, burst for a long time and does not holds back, flaccidity of limbs due to deficiency of blood Huang, Heat Diabetes;Chronic rephrilis protinuria, diabetes.
Radix Isatidis:Hardship is trembled with fear, the thoughts of returning home, stomach;Clearing heat and detoxicating, cool blood relieving sore-throat, for febrile virulent maculae, tongue is dark reddish purple dark, mumps, Larynx numbness, scarlet fever, major part pestilence, erysipelas, carbuncle swells.
Radix scutellariae:Hardship is trembled with fear, return lung, courage, spleen, large intestine, small intestinl channel;Heat-clearing and damp-drying drug rushes down people's removing toxic substances, hemostasis, tocolysis, for wet Temperature, heat temperature chest tightness and emesis, damp and hot feeling of fullness, rush down dysentery, jaundice, cough with lung heat, hyperpyrexia polydipsia, blood-head tells nosebleed, carbuncle sore tumefacting virus, movement of the foetus is not Peace.
Radix bupleuri:Hardship is slightly cold, Return liver, gallbladder channel;It is soothing the liver in inducing diaphoresis, rising Yang, for cold, fever fevers and chills alternates, chest side of body Distending pain, irregular menstruation;The prolapse of uterus, rectal prolapse.
Chinese ephedra:Pungent, slight bitter, temperature, return lung, bladder warp;Sweating cold dispelling, freeings lung and relieving asthma, inducing diuresis for removing edema, for anemofrigid cold, It is uncomfortable in chest to breath with cough, geomantic omen edema;Bronchial asthma.Herba ephedrae moistens the lung and relieve the cough.It is chiefly used in exterior syndrome to have solved, asthma and cough.
Semen armeniacae amarae:Hardship, tepor is slightly poisonous, return lung, large intestine channel;Sending down abnormally ascending is relieving cough and asthma, relaxes bowel, for cough and asthma Fullness sensation in chest abundant expectoration, deficiency of blood Tianjin is withered, dry constipation of intestines.There is sending down abnormally ascending relieving cough and asthma, relax bowel.
Honeysuckle:It is sweet, it trembles with fear, return lung, the heart, stomach;It is clearing heat and detoxicating, wind-heat dissipating, for carbuncle swells furunculosis larynx numbness, erysipelas, heat Malicious bloody flux, anemopyretic cold, warm disease heating.
Subprostrate sophora:Hardship is trembled with fear;It is toxic, it attaches to the lung and stomach meridians;Clearing heat and detoxicating, relieving sore-throat of subsiding a swelling is pented up, abscess of throat for fiery poison, Gingivitis.
Chinese violet:Bitter, acrid, cold, converge to heart and liver channels;It is clearing heat and detoxicating, cool blood detumescence, for furuncle swelling toxin, pain subcutaneous ulcer carbuncle on the back, Erysipelas, venomous snake bite.
Moxibustion Radix Glycyrrhizae:Sweet and neutral, the thoughts of returning home;Lung, spleen, stomach;Anew Issue Plate and stomach, Yiqi and vein recovery, for weakness of the spleen and the stomach lassitude hypodynamias, Severe palpilation, intermittent pulse.
Prepared RHIZOMA PINELLIZE without adju-vant:It is acrid in flavour and warm in nature, returns spleen, stomach, lung channel;Eliminating dampness and eliminating phlegm, for damp-phlegm syndrome, gastral cavilty feeling of fullness, sputum cohesion is coughed up It can not spit.
PORIA ALBA:It is sweet, light, it puts down, the thoughts of returning home, lung, spleen, kidney channel;Clearing damp and promoting diuresis, invigorating the spleen calming heart are dizzy for oedema oliguria phlegm and retained fluids Throb with fear, spleen eating less, loose stool diarrhea, confused and worried, insomnia of palpitating with fear.
Dried orange peel:It is bitter, acrid in flavour and warm in nature, return lung, the spleen channel;Regulating qi-flowing for strengthening spleen, it is eliminating dampness and eliminating phlegm, it vomits and diarrhoea for chest gastral cavity turgor deficiency of food, cough Abundant expectoration.
Rabdosia rubescens:Hardship, it is sweet, it is slightly cold, there is clearing heat and detoxicating, promoting blood circulation and stopping pain, there is good action for abscess of throat.
Continuous fiber crops rhizome of cyrtomium:Hardship is slightly cold, slightly poisonous, Return liver, stomach;Clearing heat and detoxicating, hemostasis, desinsection cures mainly epidemic disease flu, wind Thermal head pain, febrile virulent maculae, sore swollen toxin, metrostaxis, abdominal pain due to enterositosis.
Above-mentioned various material combinations use, thus established in being formulated Radix Isatidis, radix scutellariae, honeysuckle, subprostrate sophora, Chinese violet, Rabdosia rubescens, continuous numb rhizome of cyrtomium are monarch drug in a prescription, to ensure that the present composition is clearing heat and detoxicating, the effect of suppression is killed the virus, wilsonii, Radix Astragali, Radix bupleuri, moxibustion Radix Glycyrrhizae, Poria cocos, dried orange peel are ministerial drug, play regulating qi-flowing for strengthening spleen, clear wet except heat, the effect of sharp water anti-inflammatory, assist monarch drug in a prescription, by force Chemical drug power, Chinese ephedra, semen armeniacae amarae, prepared RHIZOMA PINELLIZE without adju-vant coordinating the drug actions of a prescription are adjutant, it is intended that play the work(of antitussive and antiasthmatic, above-mentioned each material combination section It learns, rationally, relieving cough and asthma, swelling and pain relieving is clearing heat and detoxicating, has the function of to be relieved respiratory symptom and liver protection shield kidney, increase Strong macrophage quantity, strengthen immunity, suitable for viral respiratory tract disease of fowl.
The positive beneficial effect of the present invention:
The Chinese medicine composition of present invention treatment viral respiratory tract disease of fowl belongs to pure Chinese medicinal preparation, pure Chinese medicine compatibility, It has no toxic side effect, liver kidney is not injured, avoid when using antibiotic the liver reaction of renal toxicity caused by poultry, simultaneously also Avoid the immune response of vaccine.
Specific embodiment
With reference to specific embodiment, the present invention is further described.
Embodiment 1
A kind of Chinese medicine composition for treating viral respiratory tract disease of fowl, is prepared from the following raw materials in parts by weight:Thorn 80 parts of slender acanthopanax, 70 parts of Radix Astragali, 80 parts of honeysuckle, 180 parts of Radix Isatidis, 60 parts of radix scutellariae, 60 parts of radix bupleuri, 80 parts of Chinese ephedra, semen armeniacae amarae 40 Part, 50 parts of subprostrate sophora, 80 parts of Chinese violet, 40 parts of moxibustion Radix Glycyrrhizae, 60 parts of prepared RHIZOMA PINELLIZE without adju-vant, 60 parts of PORIA ALBA, 100 parts of dried orange peel, Rabdosia rubescens 40 parts and continuous numb 30 parts of rhizome of cyrtomium.
The preparation method of the Chinese medicine composition of above-mentioned treatment viral respiratory tract disease of fowl includes the following steps:It will be above-mentioned Bulk pharmaceutical chemicals slice mixing is poured into pot, is added in the water of 10 times of volumes, is impregnated 30min, decoct 2 times, first pass decocts 1.5h, by medicine Soup is poured into container, adds second time 1h of decocting of 10 times of weight, and pan-fried decoction is mixed to get decoction twice.
Embodiment 2
A kind of Chinese medicine composition for treating viral respiratory tract disease of fowl, is prepared from the following raw materials in parts by weight:
82 parts of wilsonii, 70 parts of Radix Astragali, 80 parts of honeysuckle, 180 parts of Radix Isatidis, 64 parts of radix scutellariae, 64 parts of radix bupleuri, Chinese ephedra 80 Part, 40 parts of semen armeniacae amarae, 52 parts of subprostrate sophora, 80 parts of Chinese violet, 40 parts of moxibustion Radix Glycyrrhizae, 70 parts of prepared RHIZOMA PINELLIZE without adju-vant, 60 parts of PORIA ALBA, dried orange peel 100 parts, 50 parts of Rabdosia rubescens, continuous numb 30 parts of rhizome of cyrtomium.
The preparation method of the Chinese medicine composition of above-mentioned treatment viral respiratory tract disease of fowl includes the following steps:It will be above-mentioned Bulk pharmaceutical chemicals slice mixing is poured into pot, is added in the water of 15 times of volumes, is impregnated 30min, decoct 3 times, first pass decocts 1.5h, by medicine Soup is poured into container, adds second time 1h of decocting of 10 times of weight, is added the decocting third of 8 times of weight all over 1h, is decocted three times Decoction mix to get decoction.
Embodiment 3
A kind of Chinese medicine composition for treating viral respiratory tract disease of fowl, is prepared from the following raw materials in parts by weight:
95 parts of wilsonii, 80 parts of Radix Astragali, 98 parts of honeysuckle, 190 parts of Radix Isatidis, 76 parts of radix scutellariae, 76 parts of radix bupleuri, Chinese ephedra 82 Part, 44 parts of semen armeniacae amarae, 58 parts of subprostrate sophora, 100 parts of Chinese violet, 48 parts of moxibustion Radix Glycyrrhizae, 60 parts of prepared RHIZOMA PINELLIZE without adju-vant, 60 parts of PORIA ALBA, dried orange peel 100 parts, 60 parts of Rabdosia rubescens and continuous numb 30 parts of rhizome of cyrtomium.
The preparation method of the Chinese medicine composition of above-mentioned treatment viral respiratory tract disease of fowl includes the following steps:It will be above-mentioned Bulk pharmaceutical chemicals slice mixing is poured into pot, is added in the water of 13 times of volumes, is impregnated 25min, decoct 2 times, first pass decocts 1.5h, by medicine Soup is poured into container, adds second time 1h of decocting of 8 times of weight, and pan-fried decoction is mixed to get decoction twice.
Embodiment 4
A kind of Chinese medicine composition for treating viral respiratory tract disease of fowl, is prepared from the following raw materials in parts by weight:Thorn 110 parts of slender acanthopanax, 90 parts of Radix Astragali, 100 parts of honeysuckle, 200 parts of Radix Isatidis, 80 parts of radix scutellariae, 80 parts of radix bupleuri, 90 parts of Chinese ephedra, semen armeniacae amarae 60 parts, 60 parts of subprostrate sophora, 100 parts of Chinese violet, 50 parts of moxibustion Radix Glycyrrhizae, 70 parts of prepared RHIZOMA PINELLIZE without adju-vant, 70 parts of PORIA ALBA, 110 parts of dried orange peel, the winter insult 65 parts of grass and continuous numb 50 parts of rhizome of cyrtomium.
The preparation method of the Chinese medicine composition of above-mentioned treatment viral respiratory tract disease of fowl includes the following steps:It will be above-mentioned Bulk pharmaceutical chemicals slice mixing is poured into pot, is added in the water of 8 times of volumes, is impregnated 40min, decoct 2 times, first pass decocts 1.5h, by medicine Soup is poured into container, adds second time 2h of decocting of 13 times of weight, and pan-fried decoction is mixed to get decoction twice.
Clinical practice is tested:
It 2 months 2015, is breathed caused by influenza occurs for Yangcheng, Shanxi chicken house (6000 chickens suffer from breathing problem) A kind of breathing characterized by coughing, sneeze, tracheae gong sound, feed intake reduce similar non typical newcastle disease has occurred in road disease Tract disease is randomly divided into three groups, every group 2000.
1 group is tested as infection control group, is not processed.
2 groups are tested as experimental group:2 decoction drink-service of the embodiment of the present invention, instructions of taking are:Every chicken is average per consumption per day 2- 4g decoctions, 5-8h is interior have been drunk, and is continuously taken 4 days.
3 groups are tested as control group, takes tylosin (1000g/ bags, Ningxia Tairui Pharmaceutical Co., Ltd.), according to Specification is taken, and mixes drink, and the amount that 1L is watered by 500mg is administered, and is used in conjunction 5 days.
The standard of curative effect evaluation:
It cures:Diseased chicken is coughed, sneeze, and stream nose liquid symptom disappears, and chicken egg productivity of laying eggs is normal, and respiratory mucosa is in slurry The symptoms such as fluidity, catarrhal inflammation disappear.
It improves:Diseased chicken is coughed, sneeze, and stream nose liquid symptom mitigates, and chicken egg productivity of laying eggs significantly reduces, and respiratory mucosa is in slurry The remissions such as fluidity, catarrhal inflammation.
In vain:Diseased chicken is coughed, sneeze, and stream nose liquid symptom is not felt any better still or even deteriorates died, is judged as in vain.
The diseased chicken number of cure rate=healing/diseased chicken sum × 100%, the effective percentage=(diseased chicken of diseased chicken number+improvement of healing Number)/diseased chicken sum × 100%.
Result of the test is shown in Table 1.
1 Clinical efficacy result of table
Test result analysis:The cure rate of drug of the present invention reaches 96%, and effective percentage reaches 100%, laying rate 98%, with Control drug compares (with tylosin), and cure rate, effective percentage and laying rate, which have, largely to be improved, and therapeutic effect is notable.

Claims (1)

1. a kind of Chinese medicine composition for treating viral respiratory tract disease of fowl, which is characterized in that by the original of following parts by weight Material is made:82 parts of wilsonii, 70 parts of Radix Astragali, 80 parts of honeysuckle, 180 parts of Radix Isatidis, 64 parts of radix scutellariae, 64 parts of radix bupleuri, 80 parts of Chinese ephedra, 40 parts of semen armeniacae amarae, 52 parts of subprostrate sophora, 80 parts of Chinese violet, 40 parts of moxibustion Radix Glycyrrhizae, 70 parts of prepared RHIZOMA PINELLIZE without adju-vant, 60 parts of PORIA ALBA, dried orange peel 100 Part, 50 parts of Rabdosia rubescens and continuous numb 30 parts of rhizome of cyrtomium;
Decoction is made in the Chinese medicine composition, and decoction preparation method includes the following steps:The slice mixing of above-mentioned raw materials medicine is poured into In pot, the water of 15 times of volumes is added in, impregnates 30min, is decocted 3 times, first pass decocts 1.5h, and medicine soup is poured into container, then adds Enter second time 1h of decocting of 10 times of weight, add the decocting third of 8 times of weight all over 1h, the mixing of pan-fried decoction is to get soup three times Agent.
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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101455766A (en) * 2007-12-14 2009-06-17 董艳 Surge-eliminating cough-relieving medicine wine formula
CN103463346A (en) * 2013-09-23 2013-12-25 大连金鹏畜牧专业合作社 Medicine for treating chicken respiratory disease and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101455766A (en) * 2007-12-14 2009-06-17 董艳 Surge-eliminating cough-relieving medicine wine formula
CN103463346A (en) * 2013-09-23 2013-12-25 大连金鹏畜牧专业合作社 Medicine for treating chicken respiratory disease and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
中药防治鸡传染性呼吸道疾病的研究现况与展望;朱连勤等;《中兽医学杂志》;20030825(第04期);35-39 *

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