CN104998144A - Traditional Chinese medicine preparation used for treating intestinal obstruction, and preparation method thereof - Google Patents
Traditional Chinese medicine preparation used for treating intestinal obstruction, and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine preparation used for treating intestinal obstruction. The traditional Chinese medicine preparation is prepared from following main raw materials, by weight, 10 to 16 parts of pericarpium citri reticulatae viride, 5 to 12 parts of malt, 6 to 12 parts of magnolia obavata, 5 to 15 parts of folium sennae, 10 to 20 parts of ricinus communis, 3 to 8 parts of betel nut, 4 to 8 parts of szechwan Chinaberry fruit, 10 to 20 parts of pericarpium citri reticulatae, 8 to 16 parts of semen raphani, 9 to 13 parts of black soya bean, 5 to 15 parts of hawthorn, 1 to 5 parts of Sedum aizoon, and 4 to 6 parts of cortex cinnamomi. The traditional Chinese medicine preparation is capable of invigorating spleen and warming the middle warmer, activating qi for lowering adverse qi, removing food retention and promoting purgation, purgating heat and bowels, relieving swelling and pain, resolving hard lump, removing blood stasis and stimulating the menstrual flow, relieving intestinal adhesion, promoting gastrointestinal motility, improving intestinal blood circulation, reducing capillary permeability, protecting intestinal mucosal barrier and reducing bacterial translocation, and promoting inflammatory edema extinction. It is confirmed by clinical experiments that curative effect is excellent, application is convenient, economical, and safe; patient compliance is high; and the traditional Chinese medicine preparation is worthy of clinical expansion.
Description
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to one and treat ileac Chinese medicine preparation and method for making.
Background technology
Intestinal obstruction (Adhesive Intestinal Obstruction) refers to because a variety of causes causes intraperitoneal intestinal adhesion to cause intestinal contents can not pass through smoothly and run in intestinal.When intestinal contents is by being obstructed, then can produce the series of symptoms such as abdominal distention, stomachache, nausea and vomiting and dysporia.It belongs to mechanical intestinal obstruction category, can be divided into acute ileus and chronic intestinal obstruction by onset anxious delaying; Complete intestinal obstruction and incomplete intestinal obstruction can be divided into by blocking degree; High intestinal obstruction, low small intestine obstruction and obstruction of colon can be divided into by region of obstruction; Simple intestinal obstruction and strangulated intestinal obstruction is divided into for situation by intestinal tube blood.This disease part can obtain resolution of symptoms through non-operative treatment, but most of recurrent exerbation or expectant treatment invalid, still need to be treated surgically.
Namely the topmost clinical manifestation of intestinal obstruction is the symptom of mechanical intestinal obstruction: stomachache, vomiting, abdominal distention, stopping exhaust defecation.(1) suffer from abdominal pain: during intestinal obstruction, because enterokinesia strengthens, often have paroxysmal angina abdominis.There is gas to alter row in the normal self-induction abdomen of patient during stomachache outbreak, can see or lay one's hand on visible peristalsis visible intestinal peristalsis, hearing loud and sonorous borborygmus; If incomplete intestinal obstruction, when gas is by after blocking, pain suddenly alleviates or disappears; If mesentery is excessively by tractive, pain is persistence and paroxysmal increases the weight of; To late cases owing to blocking above intestinal tube overdistension, shrink weak, degree and the frequency of pain all alleviate; After there is enteroparalysis, stomachache changes persistence abdominal distention into.(2) vomit: the frequency of vomiting, vomiting amount and vomitus character are different with the height of region of obstruction.High intestinal obstruction vomiting occurs comparatively early, comparatively frequently, vomiting amount is more; When low small intestine obstruction and obstruction of colon, vomiting occurs more late, and number of times is also less, and vomiting amount is less, and vomitus often has excrement stink.(3) abdominal distention: cause abdominal distention because of dilatation of intestine when blocking.Whether abdominal distention degree is because blocking completely and region of obstruction and different.Block more complete, position is lower, and abdominal distention is more obvious; Though sometimes block completely, because intestinal tube storage function is lost, vomiting is early frequent, also can not occur abdominal distention; If do not note this situation, can cause failing to pinpoint a disease in diagnosis, mistaken diagnosis.If block intestinal tube formation to close loop, often show unsymmetry abdominal distension, sometimes can lay one's hand on the intestinal tube of expansion at this place.(4) exhaust defecation is stopped: intestinal obstruction is obstructed because intestinal contents transports, and can not excrete, therefore anus stops exhaust defecation.But must be noted that, the intestinal contents of region of obstruction far-end still can send by under wriggling.Therefore, even if block completely, before these content emptyings, patient can continue there is exhaust defecation, just after emptying, just no longer includes exhaust defecation.Certainly, block in imperfection, exhaust defecation phenomenon can not disappear completely.In addition, ileac clinical symptoms also has water, electrolyte and acid base imbalance, meet strangulatedly to block, bowel necrosis, the performances such as shock, peritonitis and gastrointestinal hemorrhage can be there is.
Intestinal obstruction focuses on prevention, and preventive measure comprises minimizing tissue ischemia, protection intestinal tube, alleviates damage, with a large amount of normal saline flushing abdominal cavity at the end of operation, removes foreign body, clot and other pollutant etc.The author thinks, simple intestinal obstruction can leading non-operative treatment, and block as early treatment after outbreak, the state of an illness to be alleviated.Treatments period answers the sings and symptoms of close observation patient to change, and as treatments period symptom increases the weight of gradually, should carry out operations research.To think that intestinal obstruction should not be performed the operation habitually in the past, thinking postoperative and still have adhesion, still intestinal obstruction can occur, is adhesion and blocking lumped together in fact.For recurrent exerbation, the intestinal obstruction affecting orthobiosis and work, organic problem must be had to exist, should operative treatment be carried out, not wait until that intestinal tube strangulation just determines operation.Adhesion between intestinal tube may, simply to only having a strap, also may be the extensive fine and close adhesion in full abdominal cavity, therefore, should carry out the preparation of the necessary adjustment comprising patient's homeostasis and each side such as operation group technique and material conditions etc. before surgery.
Authorization Notice No. CN 102380008 B(application number 201110357590.X) Chinese patent literature disclose one and treat intestinal adhesion and ileac Chinese medicine, it is characterized in that the weight of its raw material consists of: 10 parts, Semen Persicae, the Radix Paeoniae Alba 30 parts, the Radix Aucklandiae 6 parts, the Radix Linderae 12 parts, Semen Arecae 9 parts, Semen Raphani (parched) 15 parts, Cortex Magnoliae Officinalis 10 parts, 9 parts, Natrii Sulfas, Fructus Aurantii 10 parts.Application publication number CN 103638424 A(application number 201310693699.X) Chinese patent literature disclose one and treat ileac Chinese medicine, raw material composition with parts by weight is, Fructus Aurantii Immaturus 10-15, Caulis Lonicerae 10-15, Rhizoma Polygonati Odorati 8-12, Fructus Foeniculi 8-12, Radix Et Rhizoma Nardostachyos 20-25, Semen Alpiniae Katsumadai 15-20, Cortex Magnoliae Officinalis 15-20, Radix Aconiti Lateralis Preparata 10-15, Fructus Cannabis 8-12, Folium Sennae 3-6, Fructus Trichosanthis 12-16, Radix Linderae 17-22, Bulbus Lilii 10-15, the Rhizoma Atractylodis Macrocephalae 8-13, the Rhizoma Pinelliae 8-13, above-mentioned raw materials medicine is dried to grind and is ground into fine powder, cross 100 mesh sieves.
In a word, Chinese medicine achieves good curative effect in treatment primary disease, but also there are some problems: clinical also not for the medicine of spleen invigorating warming middle-JIAO, activating qi for lowering adverse qi, consumer product dredge stasis, purging heat to relax the bowels, has much room for improvement to improving the misery that intestinal obstruction brings.
Summary of the invention
For the deficiencies in the prior art, the object of this invention is to provide and a kind ofly prepare simple, taking convenience, be easy to carry, the ileac Chinese medicine preparation for the treatment of of easy clothes for a long time.This Chinese medicine preparation has spleen invigorating warming middle-JIAO, activating qi for lowering adverse qi, consumer product dredge stasis, purging heat to relax the bowels, effect of understand things pain-stopping.
Technical scheme of the present invention is:
One treats ileac Chinese medicine preparation, is prepared from by the primary raw material of following weight proportioning: Pericarpium Citri Reticulatae Viride 10-16 part, Fructus Hordei Germinatus 5-12 part, Cortex Magnoliae Officinalis 6-12 part, Folium Sennae 5-15 part, Semen Ricini 10-20 part, Semen Arecae 3-8 part, Fructus Toosendan 4-8 part, Pericarpium Citri Reticulatae 10-20 part, Semen Raphani 8-16 part, Semen sojae atricolor 9-13 part, Fructus Crataegi 5-15 part, Herba Senecionis Chrysanthemoidis 1-5 part, Cortex Cinnamomi 4-6 part.
One treats ileac Chinese medicine preparation, and preferred scheme is, is prepared from by the primary raw material of following weight proportioning: Pericarpium Citri Reticulatae Viride 11-15 part, Fructus Hordei Germinatus 7-10 part, Cortex Magnoliae Officinalis 8-10 part, Folium Sennae 8-13 part, Semen Ricini 13-18 part, Semen Arecae 5-7 part, Fructus Toosendan 5-7 part, Pericarpium Citri Reticulatae 13-18 part, Semen Raphani 10-14 part, Semen sojae atricolor 10-12 part, Fructus Crataegi 8-13 part, Herba Senecionis Chrysanthemoidis 2-4 part, Cortex Cinnamomi 4.5-5.5 part.
One treats ileac Chinese medicine preparation, and better preferred scheme is prepared from by the primary raw material of following weight proportioning: 13 parts, Pericarpium Citri Reticulatae Viride, 8.5 parts, Fructus Hordei Germinatus, Cortex Magnoliae Officinalis 9 parts, Folium Sennae 11 parts, Semen Ricini 15 parts, Semen Arecae 6 parts, Fructus Toosendan 6 parts, Pericarpium Citri Reticulatae 15 parts, Semen Raphani 12 parts, 11 parts, Semen sojae atricolor, Fructus Crataegi 11 parts, Herba Senecionis Chrysanthemoidis 3 parts, Cortex Cinnamomi 5 parts.
According to the preparation method of the ileac Chinese medicine preparation for the treatment of noted earlier, step is as follows:
(1) castor seeds shell is broken into pieces, pick kernel and be put in clean plate stand-by;
(2) by Fructus Crataegi enucleation, clean, be put in clean plate stand-by;
(3) by Folium Sennae as in marmite, soak 2-4 hour by the hot water seal of 90-100 DEG C, the consumption of hot water be the 2-6 of Folium Sennae weight doubly, filter, filtrate is for subsequent use;
(4) by Semen Raphani stripping and slicing and Semen sojae atricolor, step (1) and step (2) gains are put in electric food warmer, add clear water, soak 20-40 minute, by Pericarpium Citri Reticulatae Viride, Fructus Hordei Germinatus, Cortex Magnoliae Officinalis, Semen Arecae, Fructus Toosendan, Pericarpium Citri Reticulatae, Herba Senecionis Chrysanthemoidis and Cortex Cinnamomi are cleaned, be laid on uniformly on steaming tray, steaming tray is put in electric food warmer, big fire decocts to boiling, turn little fire and simmer 20-40 minute, in the process that little fire decocts, mixed up every five minutes, and spray the crude drug on steaming tray with yellow wine, after cooling, steamed crude drug is ground to form smalls, cross 80-120 mesh sieve stand-by, well-done crude drug is taken out, drain away the water, thick liquid is ground into large ferrum spoon, be placed on iron plate, little fire dries 2-6 minute, cool stand-by,
(5) step (4) gains and step (3) gained filtrate are mixed, be placed in container, decoct and stir, add Mel until decoction after 4-8 minute, filter after Mel melts completely, filtrate cools bottling and get final product.
Foregoing preparation method, step (3) hot water seal of 93-98 DEG C soaks 2.5-3.5 hour (preferably soaking 3 hours by the hot water seal of 95 DEG C).
Foregoing preparation method, the consumption of step (3) hot water is 3-5 times (consumption of preferred hot water is 4 times of Folium Sennae weight) of Folium Sennae weight.
Foregoing preparation method, Semen Raphani stripping and slicing and Semen sojae atricolor, step (1) and step (2) gains are put in electric food warmer by step (4), add clear water, soak and (preferably Semen Raphani stripping and slicing and Semen sojae atricolor, step (1) and step (2) gains are put in electric food warmer in 25-35 minute, add clear water, soak 30 minutes).
Foregoing preparation method, step (4) big fire decocts to boiling, turns little fire and simmers 25-35 minute (preferred big fire decocts to boiling, turns little fire and simmers 30 minutes).
Foregoing preparation method, the large ferrum spoon of step (4) is ground into thick liquid, is placed on iron plate, and little fire dries 3-5 minute (be preferably ground into thick liquid with large ferrum spoon, be placed on iron plate, little fire dries 4 minutes).
Foregoing preparation method, step (5) decocts and stirs, and adds Mel (preferably decoct while stir, add Mel until decoction after 6 minutes) until decoction after 5-7 minute.
Using method: for making the present invention reach optimum therapeuticing effect, in sooner or later taking half an hour after the meal, each 5-10ml, 5 is a course for the treatment of.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Pericarpium Citri Reticulatae Viride: bitter in the mouth, pungent, warm in nature.Gui Jing returns liver, gallbladder, stomach warp.Function has soothing the liver dispelling the stagnated QI, effect that removing food stagnancyization is stagnant.Cure mainly for distending pain in the chest and hypochondrium, hernia pain, nodules of the breast, acute mastitis, stagnation of QI due to dyspepsia, abdominal distention.
Fructus Hordei Germinatus: sweet is flat.Gui Jing returns spleen, stomach warp.Effect promote qi circulation digestion promoting, spleen benefiting and stimulating the appetite, galactopoiesis relieving distension.Cure mainly and do not disappear for food stagnation, abdominal distention, insufficiency of the spleen lack of appetite, milk smoulders, distending pain of the breast, and women weans, hypochondriac pain due to stagnation of liverQI, stomachache due to hyperactive liver-QI attacking the stomach.
Cortex Magnoliae Officinalis: Gui Jing: spleen channel; Stomach warp; Large intestine channel.Function: circulation of qi promoting removing food stagnancy; Dampness is except full; Lowering the adverse QI to relieve asthma.Cure mainly: stagnation of QI due to dyspepsia; Abdominal distention constipation; Retention of dampness in middle-JIAO, gastral cavity painful abdominal mass is vomited and diarrhoea; Expectorant stops up QI rising in reverse order; Fullness in the chest is breathed with cough.
Folium Sennae: nature and flavor: sweet, bitter, cold, slightly poisonous.Folium Sennae return through: return large intestine channel.Cure mainly: the row that purges heat is stagnant, relieving constipation, diuretic.Stagnate for accumulation of heat, constipation is suffered from abdominal pain, edema distension.
Semen Ricini: leaf: sweet, pungent, flat.Slightly poisonous.Root: light, micro-pungent is flat.Function cures mainly leaf: detumescence and drawing out poison, antipruritic.Control sore swollen toxin, fresh goods mashes external application; Control eczema to scratch where it itches, decoction being used as a lotion; And maggot of can going out, infanticide Jue.Root: expelling wind and activating blood circulation, pain relieving is calm.For rheumatic arthritis, tetanus, epilepsy, schizophrenia.Tranquillizing to relieve muscle spasm, dispel the wind dissipating blood stasis.Control tetanus, epilepsy, rheumatalgia, traumatic injury stasis of blood pain, scrofula.
Semen Arecae: arecoline is effective anthelmintic ingredient, has cestode and significantly causes paralysis effect, have inhibitory action in various degree to dermatophytess such as trichophytons.In addition, the effect of arecoline is similar to pilocarpine effect, can glandular secretion be caused to increase by excited M-cholinoceptor, contracted pupil, shrinks bronchus, decreased heart rate, vasodilation, blood pressure drops.Prove in Semen Arecae containing the material to human carcinogen simultaneously.Clinically be usually used in the diseases such as worm disease, ascites, dyspepsia.Toxicity: excessive arecoline causes sialorrhea, vomiting, diuresis, lethargy and convulsions.
Fructus Toosendan: bitter, cold.Gui Jing returns liver, small intestinal, urinary bladder channel.Effect is soothing the liver to expel the heat-evil, promoting the circulation of QI to relieve pain, parasite killing.Cure mainly for pathogenic fire derived from stagnation of liver-QI, the breast side of body, abdominal distention, hernia pain, abdominal pain due to worm stagnation.
Pericarpium Citri Reticulatae: bitter in the mouth, pungent, warm in nature.Gui Jing returns lung, spleen channel.Effect regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.Cure mainly for distension and fullness in the abdomen, lack of appetite and vomiting, cough with copious phlegm.
Semen Raphani: base is former: be fresh of Cruciferae Radix Raphani platymiscium Radix Raphani.Composition: root contains glycoside glucosinolate, glucose raphanin, raphanusin.Phenolic acids: P-coumaric acid, caffeic acid, ferulic acid, phenylpyruvic acid, gentisic acid etc.The property of medicine: acrid, sweet, cool; Ripe person is sweet, flat.Return spleen, stomach, lung, large intestine channel.Function cures mainly: help digestion, and the therapeutic method to keep the adverse QI flowing downwards is reduced phlegm, hemostasis.Cure mainly dyspepsia, food stagnation distension, acid regurgitation, regurgitation of food from the stomach, tells food, and hemorrhoidal hamorrhage is had loose bowels, dysentery, constipation, phlegm-heat cough, discomfort in the throat, hemoptysis, and spit blood, epistaxis, has blood in stool, and quenches one's thirst, and drenches worm.Outer treatment skin ulcer abscess, damage congestive edema, scalds and chilblain.
Semen sojae atricolor: Semen sojae atricolor it except returning kidney channel because it is sweet in the mouth, it also enters spleen channel.Enter spleen channel, he is except there being the effect of the kidney invigorating, and it also has the effect of spleen invigorating.The traditional Chinese medical science, Chinese medicine spleen invigorating, he is exactly the effect of an invigorating the spleen and benefiting QI.Often eat Semen sojae atricolor, one is to make the mechanism of qi of we people be improved, and simultaneously Semen sojae atricolor can also be dispelled the effect of water.Such as our some people's edema, face is red and swollen, and eating Semen sojae atricolor for a long time can well diuretic effect.Semen sojae atricolor fries rear xerophagia, protein digestibility extreme difference, easily stops up gas heat-dissipating, occurs the symptoms such as vexed, irritable, thirsty, constipation, dark coloured urine.Therefore, suggestion at ordinary times edible Semen sojae atricolor time preferably cook or eat again after making the bean product such as bean milk, bean curd.
Fructus Crataegi: stone fruit, caryoplasm is hard, and sarcocarp is thin, and taste is micro-sour and astringent.Fruit is raw-eaten or make preserved fruit fruitcake, can be used as medicine after drying, Chinese distinctive medicine fruit dual-purpose seeds, there is the effects such as blood fat reducing, blood pressure, heart tonifying, arrhythmia, also be simultaneously the good medicine of spleen benefiting and stimulating the appetite, relieving dyspepsia, phlegm reduction of blood circulation promoting, the disease such as, hernia, blood stasis full to chest and diaphragm spleen, amenorrhea has good curative effect.Flavone compound vitexin in Fructus Crataegi is the medicine that a kind of antitumaous effect is stronger, and its extract all has certain effect to growth of cancer cells, propagation and infiltration metastasis in suppression body.
Herba Senecionis Chrysanthemoidis: base is former: be root or the herb of Compositae Radix Gynurae platymiscium chrysanthemum leaf Radix Notoginseng.Composition: root is containing alkaloid: aureine., senlciphylline, sineciphyllinine, seneciphyllinine etc.Aerial parts contains PEARLITOL 25C, succinic acid, 5-methyl uracil, adenine, ammonium chloride, Radix gynurae segeti bases, rutin.The property of medicine: sweet, micro-hardship, temperature.Function cures mainly: removing blood stasis, detumescence, hemostasis, pain relieving.Cure mainly treating swelling and pain by traumatic injury, traumatic hemorrhage, congestion is spitted blood, epistaxis, and spitting of blood, has blood in stool, metrorrhagia, dysmenorrhea, stomachache of being retarded by silt puerperal, rheumatalgia, carbuncle sore cellulitis furuncle, worm venom.
Cortex Cinnamomi: base is former: be dried bark, the branch skin of Lauraceae cinnamon Cortex Cinnamomi.Composition: Cortex cinnamomi japonici (Ramulus Cinnamomi) is containing volatile oil 1.89%-2.06%, and its main component is cinnamic aldehyde, accounts for 52.92%-61.20%, also has acetic acid Cortex cinnamomi japonici (Ramulus Cinnamomi) ester, ethyl cinnamate, benzaldehyde benzyl ester, benzaldehyde, coumarin etc.The property of medicine: pungent, sweet, heat.Return kidney, spleen, the heart, Liver Channel.Function cures mainly: mend fire supporing yang, dispersing cold for relieving pain, warming the meridian and promoting blood circulation.Cure mainly insufficiency of kidney-YANG, the aversion to cold and cold limbs of decline of the fire from the gate of life, soreness of the waist and knees, impotence and seminal emission, dysuria or frequency, dyspnea with rapid and short breath of losing heart, all diseases of edema oliguria; Decline of the fire from the gate of life, fire is Gui Yuan not, floating YANG, refusing yang, and heat in the upper and cold in the lower, flushed complexion cold foot, dizziness and tinnitus, and dispute gruel is broken; Spleen-kidney vacuity cold, coldness and pain in the epigastrium, decreased food intake loose stool; Lumbago due to renal deficiency; Arthralgia due to cold-dampnes; Colic of cold type pain, cold womb is infertile, dysmenorrhea amenorrhea, stomachache of being retarded by silt puerperal; Carbuncle of yin nature multiple abscess, or deficiency and coldness carbuncle and ulcer difficulty in discharging of pus, or do not hold back after bursting.
Chinese medicine preparation scientific formula provided by the invention, the preparation method of dosage form is simple, products obtained therefrom taking convenience, is easy to carry.In addition, excellent results of the present invention also shows:
1, selected materials is all Chinese medicine material, without any side effects, can improve intestinal blood circulation, reduce capillary permeability, protects gut barrier and reduce bacterial translocation, promotion inflammation edema extinction;
2, this prescription meets Chinese medicine principle and ileac patient's body and mind feature completely, under the prerequisite of general principle, can have different prescription according to different crowd, and function is different.
3, medicine source is easy to get, and medical material is with low cost, can relieve patient ' s burden.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
embodiment 1one treats ileac Chinese medicine preparation, gets the raw materials ready (getting 10g for every part): Pericarpium Citri Reticulatae Viride 10-16 part by following weight parts, Fructus Hordei Germinatus 5-12 part, Cortex Magnoliae Officinalis 6-12 part, Folium Sennae 5-15 part, Semen Ricini 10-20 part, Semen Arecae 3-8 part, Fructus Toosendan 4-8 part, Pericarpium Citri Reticulatae 10-20 part, Semen Raphani 8-16 part, Semen sojae atricolor 9-13 part, Fructus Crataegi 5-15 part, Herba Senecionis Chrysanthemoidis 1-5 part, Cortex Cinnamomi 4-6 part.
The preparation method of the ileac Chinese medicine preparation of above-mentioned treatment:
(1) castor seeds shell is broken into pieces, pick kernel and be put in clean plate stand-by;
(2) by Fructus Crataegi enucleation, clean, be put in clean plate stand-by;
(3) by Folium Sennae as in marmite, soak 2 hours by the hot water seal of 90 DEG C, the consumption of hot water is 2 times of Folium Sennae weight, filter, filtrate is for subsequent use;
(4) by Semen Raphani stripping and slicing and Semen sojae atricolor, step (1) and step (2) gains are put in electric food warmer, add clear water, soak 20 minutes, by Pericarpium Citri Reticulatae Viride, Fructus Hordei Germinatus, Cortex Magnoliae Officinalis, Semen Arecae, Fructus Toosendan, Pericarpium Citri Reticulatae, Herba Senecionis Chrysanthemoidis and Cortex Cinnamomi are cleaned, be laid on uniformly on steaming tray, steaming tray is put in electric food warmer, big fire decocts to boiling, turn little fire and simmer 20 minutes, in the process that little fire decocts, mixed up every five minutes, and spray the crude drug on steaming tray with yellow wine, after cooling, steamed crude drug is ground to form smalls, cross 80 mesh sieves stand-by, well-done crude drug is taken out, drain away the water, thick liquid is ground into large ferrum spoon, be placed on iron plate, little fire dries 2 minutes, cool stand-by,
(5) step (4) gains and step (3) gained filtrate are mixed, be placed in container, decoct and stir, add Mel until decoction after 4 minutes, filter after Mel melts completely, filtrate cools bottling and get final product.
typical case one: Zou XX, man 35 years old.Jinan personage, the employee of certain company, the abdominal distention of unknown cause was there is before 2 months, the symptoms such as stomachache, originally think and oneself eaten thing bad, buy JIANWEI XIAOSHI PIAN voluntarily to take, effective when taking at the beginning, serious all the more after drug withdrawal, the hospital of accompanying down of layman checks, periappendiceal abscess hands art was done in patient's readme before 5 months, doctor is through checking, find that patient suffers from intestinal adhesion, pressing patient umbilicus Zhou Mingxian tenderness, without rebound tenderness, without enclosed mass, abdominal distention is not relaxed, there is the symptom of feeling sick and kecking, periappendiceal abscess hands art was done due in patient nearly half a year, so patient-requested medication's treatment.
Give the oral embodiment of the present invention 1 gained preparation, after 3 days, the symptom of patient's self-induction abdominal distention, stomachache alleviates to some extent, and after continuing to have taken 1 course for the treatment of, malaise symptoms disappears substantially, continues again to take 1 course for the treatment of, cures completely, not showing effect more so far 1 year.
embodiment 2one treats ileac Chinese medicine preparation, gets the raw materials ready (getting 15g for every part): 16 parts, Pericarpium Citri Reticulatae Viride by following weight parts, 12 parts, Fructus Hordei Germinatus, Cortex Magnoliae Officinalis 12 parts, Folium Sennae 15 parts, Semen Ricini 20 parts, Semen Arecae 8 parts, Fructus Toosendan 8 parts, Pericarpium Citri Reticulatae 20 parts, Semen Raphani 16 parts, 13 parts, Semen sojae atricolor, Fructus Crataegi 15 parts, Herba Senecionis Chrysanthemoidis 5 parts, Cortex Cinnamomi 6 parts.
The preparation method of the ileac Chinese medicine preparation of above-mentioned treatment is:
(1) castor seeds shell is broken into pieces, pick kernel and be put in clean plate stand-by;
(2) by Fructus Crataegi enucleation, clean, be put in clean plate stand-by;
(3) by Folium Sennae as in marmite, soak 4 hours by the hot water seal of 100 DEG C, the consumption of hot water is 6 times of Folium Sennae weight, filter, filtrate is for subsequent use;
(4) by Semen Raphani stripping and slicing and Semen sojae atricolor, step (1) and step (2) gains are put in electric food warmer, add clear water, soak 40 minutes, by Pericarpium Citri Reticulatae Viride, Fructus Hordei Germinatus, Cortex Magnoliae Officinalis, Semen Arecae, Fructus Toosendan, Pericarpium Citri Reticulatae, Herba Senecionis Chrysanthemoidis and Cortex Cinnamomi are cleaned, be laid on uniformly on steaming tray, steaming tray is put in electric food warmer, big fire decocts to boiling, turn little fire and simmer 40 minutes, in the process that little fire decocts, mixed up every five minutes, and spray the crude drug on steaming tray with yellow wine, after cooling, steamed crude drug is ground to form smalls, cross 120 mesh sieves stand-by, well-done crude drug is taken out, drain away the water, thick liquid is ground into large ferrum spoon, be placed on iron plate, little fire dries 6 minutes, cool stand-by,
(5) step (4) gains and step (3) gained filtrate are mixed, be placed in container, decoct and stir, add Mel until decoction after 8 minutes, filter after Mel melts completely, filtrate cools bottling and get final product.
typical case two:woods XX, female, 42 years old, Jiyang, Jinan personage, peasant, because of paroxysmal abdominal pain abdominal distention before 3 months, non-defecation aerofluxus was admitted to hospital for 3 days.Readme before 1 year because of bilateral ovaries tumor, side Ovarian Tumors with Twisted Pedicle hospitalisation for surgery.Health check-up: full abdominal pressure pain, auscultation borborygmus is obviously hyperfunction, and x-ray fluoroscopy jejunum and ileum has fluid level, and be diagnosed as intestinal adhesion companion intestinal obstruction, due to patient's financial difficulties, so do not want to perform the operation, doctor advised takes Chinese medicine preparation of the present invention.
Take the embodiment of the present invention 2 gained Chinese medicine preparation, after 2 days, patient's readme, defecation is smooth and easy, and the symptom of abdominal distention alleviates, and pain has remained dormant for 1 day, and after continuing again to take 1 course for the treatment of, malaise symptoms disappears substantially, without recurrence after drug withdrawal.
embodiment 3one treats ileac Chinese medicine preparation, gets the raw materials ready (getting 20g for every part): 11 parts, Pericarpium Citri Reticulatae Viride by following weight parts, 7 parts, Fructus Hordei Germinatus, Cortex Magnoliae Officinalis 8 parts, Folium Sennae 8 parts, Semen Ricini 13 parts, Semen Arecae 5 parts, Fructus Toosendan 5 parts, Pericarpium Citri Reticulatae 13 parts, Semen Raphani 10 parts, 10 parts, Semen sojae atricolor, Fructus Crataegi 8 parts, Herba Senecionis Chrysanthemoidis 2 parts, Cortex Cinnamomi 4.5 parts.
The preparation method of the ileac Chinese medicine preparation of above-mentioned treatment is:
(1) castor seeds shell is broken into pieces, pick kernel and be put in clean plate stand-by;
(2) by Fructus Crataegi enucleation, clean, be put in clean plate stand-by;
(3) by Folium Sennae as in marmite, soak 2.5 hours by the hot water seal of 93 DEG C, the consumption of hot water is 3 times of Folium Sennae weight, filter, filtrate is for subsequent use;
(4) by Semen Raphani stripping and slicing and Semen sojae atricolor, step (1) and step (2) gains are put in electric food warmer, add clear water, soak 25 minutes, by Pericarpium Citri Reticulatae Viride, Fructus Hordei Germinatus, Cortex Magnoliae Officinalis, Semen Arecae, Fructus Toosendan, Pericarpium Citri Reticulatae, Herba Senecionis Chrysanthemoidis and Cortex Cinnamomi are cleaned, be laid on uniformly on steaming tray, steaming tray is put in electric food warmer, big fire decocts to boiling, turn little fire and simmer 25 minutes, in the process that little fire decocts, mixed up every five minutes, and spray the crude drug on steaming tray with yellow wine, after cooling, steamed crude drug is ground to form smalls, cross 90 mesh sieves stand-by, well-done crude drug is taken out, drain away the water, thick liquid is ground into large ferrum spoon, be placed on iron plate, little fire dries 3 minutes, cool stand-by,
(5) step (4) gains and step (3) gained filtrate are mixed, be placed in container, decoct and stir, add Mel until decoction after 5 minutes, filter after Mel melts completely, filtrate cools bottling and get final product.
typical case three:temperature XX, man, 34 years old, Jinan, Shandong Province personage, civil servant, last year, because of traffic accident rupture of spleen, enterorrhexis operative treatment, performed the operation very well, without exception when leaving hospital.After 1 year, patient is because of eating and drinking without temperance sense paroxysmal abdominal pain, nausea and vomiting, abdominal tympanites, not defecation also not aerofluxus, dare not have a meal more, but hunger again very, Sui Qu hospital checks, doctor, by going the inquiry of patient and being diagnosed as intestinal obstruction in conjunction with medical history, takes invention formulation.
Take the embodiment of the present invention 3 gained Chinese medicine preparation, after 1 course for the treatment of, patient's sensation is so inviolent in pain, does not have the symptoms such as Nausea and vomiting yet, after continuing to take 1 course for the treatment of, basic malaise symptoms disappears, and the state of an illness is basicly stable, continue to take to do 1 course for the treatment of and consolidate, without recurrence after drug withdrawal.
embodiment 4one treats ileac Chinese medicine preparation, gets the raw materials ready (getting 25g for every part): 15 parts, Pericarpium Citri Reticulatae Viride by following weight parts, 10 parts, Fructus Hordei Germinatus, Cortex Magnoliae Officinalis 10 parts, Folium Sennae 13 parts, Semen Ricini 18 parts, Semen Arecae 7 parts, Fructus Toosendan 7 parts, Pericarpium Citri Reticulatae 18 parts, Semen Raphani 14 parts, 12 parts, Semen sojae atricolor, Fructus Crataegi 13 parts, Herba Senecionis Chrysanthemoidis 4 parts, Cortex Cinnamomi 5.5 parts.
The preparation method of the ileac Chinese medicine preparation of above-mentioned treatment is:
(1) castor seeds shell is broken into pieces, pick kernel and be put in clean plate stand-by;
(2) by Fructus Crataegi enucleation, clean, be put in clean plate stand-by;
(3) by Folium Sennae as in marmite, soak 3.5 hours by the hot water seal of 98 DEG C, the consumption of hot water is 5 times of Folium Sennae weight, filter, filtrate is for subsequent use;
(4) by Semen Raphani stripping and slicing and Semen sojae atricolor, step (1) and step (2) gains are put in electric food warmer, add clear water, soak 35 minutes, by Pericarpium Citri Reticulatae Viride, Fructus Hordei Germinatus, Cortex Magnoliae Officinalis, Semen Arecae, Fructus Toosendan, Pericarpium Citri Reticulatae, Herba Senecionis Chrysanthemoidis and Cortex Cinnamomi are cleaned, be laid on uniformly on steaming tray, steaming tray is put in electric food warmer, big fire decocts to boiling, turn little fire and simmer 35 minutes, in the process that little fire decocts, mixed up every five minutes, and spray the crude drug on steaming tray with yellow wine, after cooling, steamed crude drug is ground to form smalls, cross 110 mesh sieves stand-by, well-done crude drug is taken out, drain away the water, thick liquid is ground into large ferrum spoon, be placed on iron plate, little fire dries 5 minutes, cool stand-by,
(5) step (4) gains and step (3) gained filtrate are mixed, be placed in container, decoct and stir, add Mel until decoction after 7 minutes, filter after Mel melts completely, filtrate cools bottling and get final product.
embodiment 5one treats ileac Chinese medicine preparation, gets the raw materials ready (getting 30g for every part): 13 parts, Pericarpium Citri Reticulatae Viride by following weight parts, 8.5 parts, Fructus Hordei Germinatus, Cortex Magnoliae Officinalis 9 parts, Folium Sennae 11 parts, Semen Ricini 15 parts, Semen Arecae 6 parts, Fructus Toosendan 6 parts, Pericarpium Citri Reticulatae 15 parts, Semen Raphani 12 parts, 11 parts, Semen sojae atricolor, Fructus Crataegi 11 parts, Herba Senecionis Chrysanthemoidis 3 parts, Cortex Cinnamomi 5 parts.
The preparation method of the ileac Chinese medicine preparation of above-mentioned treatment is:
(1) castor seeds shell is broken into pieces, pick kernel and be put in clean plate stand-by;
(2) by Fructus Crataegi enucleation, clean, be put in clean plate stand-by;
(3) by Folium Sennae as in marmite, soak 3 hours by the hot water seal of 95 DEG C, the consumption of hot water is 4 times of Folium Sennae weight, filter, filtrate is for subsequent use;
(4) by Semen Raphani stripping and slicing and Semen sojae atricolor, step (1) and step (2) gains are put in electric food warmer, add clear water, soak 30 minutes, by Pericarpium Citri Reticulatae Viride, Fructus Hordei Germinatus, Cortex Magnoliae Officinalis, Semen Arecae, Fructus Toosendan, Pericarpium Citri Reticulatae, Herba Senecionis Chrysanthemoidis and Cortex Cinnamomi are cleaned, be laid on uniformly on steaming tray, steaming tray is put in electric food warmer, big fire decocts to boiling, turn little fire and simmer 30 minutes, in the process that little fire decocts, mixed up every five minutes, and spray the crude drug on steaming tray with yellow wine, after cooling, steamed crude drug is ground to form smalls, cross 100 mesh sieves stand-by, well-done crude drug is taken out, drain away the water, thick liquid is ground into large ferrum spoon, be placed on iron plate, little fire dries 4 minutes, cool stand-by,
(5) step (4) gains and step (3) gained filtrate are mixed, be placed in container, decoct and stir, add Mel until decoction after 6 minutes, filter after Mel melts completely, filtrate cools bottling and get final product.
test example 1in order to verify the effect of Chinese medicine preparation of the present invention, from in January, 2012 in January, 2015 in 4 hospitals, have chosen the experiment (embodiment 5) that 400 routine intestinal obstruction patients have carried out medicine, be divided into matched group and experimental group, matched group 200 people, experimental group 200 people, matched group uses the ileac Western medicine of other treatment (as conventional medication such as conventional medication such as Fufang Dachegqi Tang, Euphorbiae Kansui Decoction for Treating Intestinal Obstruction, Intestinal adhesion lysis soup and wenpi decoctions), experimental group uses gained Chinese medicine preparation of the present invention
Using method: for making the present invention reach optimum therapeuticing effect, in sooner or later taking half an hour after the meal, each 5-10ml, 5 is a course for the treatment of.
Curative effect situation criterion: cure: after taking this product, malaise symptoms has clear improvement, pain disappears; Effective: after taking this product, malaise symptoms makes moderate progress, and abdominal distention, stomachache alleviate to some extent; Invalid: after taking this product, malaise symptoms is unchanged.Result is as shown in table 1.
Specific experiment result is as following table:
Table 1:
Between the operating period, patient's self-induction symptom is as shown in table 2:
Table 2:
Prove through clinical trial, use compared with Chinese medicine preparation of the present invention alleviates ileac means with doctor trained in Western medicine, treatment means is more comprehensive thoroughly, has no side effect between the operating period, alleviating ileac while, the symptom such as pain, inappetence, general weakness brought by intestinal obstruction can be alleviated.Prove through clinical trial, Chinese drugs agentia effective percentage of the present invention is 97%.Take 3 days, more than 80% feel takes a turn for the better to some extent, malaise symptoms improves, pain alleviates to some extent, the present invention has spleen invigorating warming middle-JIAO, activating qi for lowering adverse qi, consumer product dredge stasis, purging heat to relax the bowels, reducing swelling and alleviating pain, hard masses softening and resolving, effect of eliminating blood stasis and inducing menstruation, can to loosen intestinal adhesion, increase gastrointestinal peristalsis, improve intestinal blood circulation, reduce capillary permeability, protect gut barrier and reduce bacterial translocation, promote inflammation edema extinction, and enterobacteria can be suppressed to grow, finally reach promotion aerofluxus, defecation, anti-inflammation detumescence, alleviate abdominal distention stomachache, recover the effect of gastrointestinal function, remarkable through clinical proof clinical efficacy of the present invention, easy to use, economical, safety, patient compliance is high, clinic is promoted.
Claims (10)
1. treat an ileac Chinese medicine preparation, it is characterized in that: be prepared from by the primary raw material of following weight proportioning: Pericarpium Citri Reticulatae Viride 10-16 part, Fructus Hordei Germinatus 5-12 part, Cortex Magnoliae Officinalis 6-12 part, Folium Sennae 5-15 part, Semen Ricini 10-20 part, Semen Arecae 3-8 part, Fructus Toosendan 4-8 part, Pericarpium Citri Reticulatae 10-20 part, Semen Raphani 8-16 part, Semen sojae atricolor 9-13 part, Fructus Crataegi 5-15 part, Herba Senecionis Chrysanthemoidis 1-5 part, Cortex Cinnamomi 4-6 part.
2. the ileac Chinese medicine preparation for the treatment of according to claim 1, is characterized in that: be prepared from by the primary raw material of following weight proportioning: Pericarpium Citri Reticulatae Viride 11-15 part, Fructus Hordei Germinatus 7-10 part, Cortex Magnoliae Officinalis 8-10 part, Folium Sennae 8-13 part, Semen Ricini 13-18 part, Semen Arecae 5-7 part, Fructus Toosendan 5-7 part, Pericarpium Citri Reticulatae 13-18 part, Semen Raphani 10-14 part, Semen sojae atricolor 10-12 part, Fructus Crataegi 8-13 part, Herba Senecionis Chrysanthemoidis 2-4 part, Cortex Cinnamomi 4.5-5.5 part.
3. the ileac Chinese medicine preparation for the treatment of according to claim 1, is characterized in that: be prepared from by the primary raw material of following weight proportioning: 13 parts, Pericarpium Citri Reticulatae Viride, 8.5 parts, Fructus Hordei Germinatus, Cortex Magnoliae Officinalis 9 parts, Folium Sennae 11 parts, Semen Ricini 15 parts, Semen Arecae 6 parts, Fructus Toosendan 6 parts, Pericarpium Citri Reticulatae 15 parts, Semen Raphani 12 parts, 11 parts, Semen sojae atricolor, Fructus Crataegi 11 parts, Herba Senecionis Chrysanthemoidis 3 parts, Cortex Cinnamomi 5 parts.
4. according to the preparation method of the ileac Chinese medicine preparation of the treatment according to any one of claim 1-3, it is characterized in that: step is as follows:
(1) castor seeds shell is broken into pieces, pick kernel and be put in clean plate stand-by;
(2) by Fructus Crataegi enucleation, clean, be put in clean plate stand-by;
(3) by Folium Sennae as in marmite, soak 2-4 hour by the hot water seal of 90-100 DEG C, the consumption of hot water be the 2-6 of Folium Sennae weight doubly, filter, filtrate is for subsequent use;
(4) by Semen Raphani stripping and slicing and Semen sojae atricolor, step (1) and step (2) gains are put in electric food warmer, add clear water, soak 20-40 minute, by Pericarpium Citri Reticulatae Viride, Fructus Hordei Germinatus, Cortex Magnoliae Officinalis, Semen Arecae, Fructus Toosendan, Pericarpium Citri Reticulatae, Herba Senecionis Chrysanthemoidis and Cortex Cinnamomi are cleaned, be laid on uniformly on steaming tray, steaming tray is put in electric food warmer, big fire decocts to boiling, turn little fire and simmer 20-40 minute, in the process that little fire decocts, mixed up every five minutes, and spray the crude drug on steaming tray with yellow wine, after cooling, steamed crude drug is ground to form smalls, cross 80-120 mesh sieve stand-by, well-done crude drug is taken out, drain away the water, thick liquid is ground into large ferrum spoon, be placed on iron plate, little fire dries 2-6 minute, cool stand-by,
(5) step (4) gains and step (3) gained filtrate are mixed, be placed in container, decoct and stir, add Mel until decoction after 4-8 minute, filter after Mel melts completely, filtrate cools bottling and get final product.
5. preparation method according to claim 4, is characterized in that: step (3) hot water seal of 93-98 DEG C soaks 2.5-3.5 hour (preferably soaking 3 hours by the hot water seal of 95 DEG C).
6. preparation method according to claim 4, is characterized in that: the consumption of step (3) hot water is 3-5 times (consumption of preferred hot water is 4 times of Folium Sennae weight) of Folium Sennae weight.
7. preparation method according to claim 4, it is characterized in that: Semen Raphani stripping and slicing and Semen sojae atricolor, step (1) and step (2) gains are put in electric food warmer by step (4), add clear water, soak and (preferably Semen Raphani stripping and slicing and Semen sojae atricolor, step (1) and step (2) gains are put in electric food warmer in 25-35 minute, add clear water, soak 30 minutes).
8. preparation method according to claim 4, is characterized in that: step (4) big fire decocts to boiling, turns little fire and simmers 25-35 minute (preferred big fire decocts to boiling, turns little fire and simmers 30 minutes).
9. preparation method according to claim 4, is characterized in that: the large ferrum spoon of step (4) is ground into thick liquid, is placed on iron plate, and little fire dries 3-5 minute (be preferably ground into thick liquid with large ferrum spoon, be placed on iron plate, little fire dries 4 minutes).
10. preparation method according to claim 4, is characterized in that: step (5) decocts and stirs, and adds Mel (preferably decoct while stir, add Mel until decoction after 6 minutes) until decoction after 5-7 minute.
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| CN105497675A (en) * | 2016-01-30 | 2016-04-20 | 王月水 | Oral liquid for treating ileus and preparation method of oral liquid |
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|---|---|---|---|---|
| CN101732628A (en) * | 2010-01-26 | 2010-06-16 | 黄毅 | Chinese medicament for treating intestinal obstruction |
| CN104189772A (en) * | 2014-09-19 | 2014-12-10 | 宋秀花 | Traditional Chinese medicine for treating adhesive intestinal obstruction |
| CN104435521A (en) * | 2014-06-09 | 2015-03-25 | 彭衍琛 | Traditional Chinese medicine preparation for treating adhesive ileus and preparation method |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101732628A (en) * | 2010-01-26 | 2010-06-16 | 黄毅 | Chinese medicament for treating intestinal obstruction |
| CN104435521A (en) * | 2014-06-09 | 2015-03-25 | 彭衍琛 | Traditional Chinese medicine preparation for treating adhesive ileus and preparation method |
| CN104189772A (en) * | 2014-09-19 | 2014-12-10 | 宋秀花 | Traditional Chinese medicine for treating adhesive intestinal obstruction |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105497675A (en) * | 2016-01-30 | 2016-04-20 | 王月水 | Oral liquid for treating ileus and preparation method of oral liquid |
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Application publication date: 20151028 |