CN104984448B - A kind of Diskus - Google Patents
A kind of Diskus Download PDFInfo
- Publication number
- CN104984448B CN104984448B CN201510466553.0A CN201510466553A CN104984448B CN 104984448 B CN104984448 B CN 104984448B CN 201510466553 A CN201510466553 A CN 201510466553A CN 104984448 B CN104984448 B CN 104984448B
- Authority
- CN
- China
- Prior art keywords
- main body
- capsule
- diskus
- medicine support
- suction nozzle
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
- 239000002775 capsule Substances 0.000 claims abstract description 65
- 239000003814 drug Substances 0.000 claims abstract description 42
- 229940079593 drug Drugs 0.000 claims description 11
- 238000009434 installation Methods 0.000 claims description 8
- 239000003292 glue Substances 0.000 claims description 3
- 238000005034 decoration Methods 0.000 claims 1
- 210000003128 head Anatomy 0.000 description 13
- 239000002245 particle Substances 0.000 description 9
- 239000000843 powder Substances 0.000 description 8
- 230000000694 effects Effects 0.000 description 5
- 238000003756 stirring Methods 0.000 description 5
- 230000008901 benefit Effects 0.000 description 4
- 239000000428 dust Substances 0.000 description 4
- 210000004072 lung Anatomy 0.000 description 4
- 238000011282 treatment Methods 0.000 description 4
- 238000000034 method Methods 0.000 description 3
- 239000003380 propellant Substances 0.000 description 3
- 210000002345 respiratory system Anatomy 0.000 description 3
- UPMLOUAZCHDJJD-UHFFFAOYSA-N 4,4'-Diphenylmethane Diisocyanate Chemical compound C1=CC(N=C=O)=CC=C1CC1=CC=C(N=C=O)C=C1 UPMLOUAZCHDJJD-UHFFFAOYSA-N 0.000 description 2
- 229920000538 Poly[(phenyl isocyanate)-co-formaldehyde] Polymers 0.000 description 2
- 208000006673 asthma Diseases 0.000 description 2
- 230000001684 chronic effect Effects 0.000 description 2
- 230000000875 corresponding effect Effects 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 238000001647 drug administration Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 210000000214 mouth Anatomy 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 description 1
- 208000019693 Lung disease Diseases 0.000 description 1
- CBENFWSGALASAD-UHFFFAOYSA-N Ozone Chemical compound [O-][O+]=O CBENFWSGALASAD-UHFFFAOYSA-N 0.000 description 1
- 206010035664 Pneumonia Diseases 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 239000000443 aerosol Substances 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 210000000621 bronchi Anatomy 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 230000002079 cooperative effect Effects 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 229940112141 dry powder inhaler Drugs 0.000 description 1
- 239000003344 environmental pollutant Substances 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 239000010419 fine particle Substances 0.000 description 1
- 238000010579 first pass effect Methods 0.000 description 1
- 150000005828 hydrofluoroalkanes Chemical class 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 210000004379 membrane Anatomy 0.000 description 1
- 229940071648 metered dose inhaler Drugs 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 239000006199 nebulizer Substances 0.000 description 1
- 230000000414 obstructive effect Effects 0.000 description 1
- 238000011369 optimal treatment Methods 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 231100000719 pollutant Toxicity 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 230000001960 triggered effect Effects 0.000 description 1
Abstract
The invention discloses a kind of Diskus, include main body, suction nozzle is equipped with described main body one end, the medicine support that can be rotated is equipped with the main body, several capsule chambers for being used to place capsule are equipped with the medicine support, the through hole of capsule chamber and suction nozzle can be connected by being equipped with the main body, the piercing device for being placed on the indoor capsule of capsule can be pierced through by being equipped with the body, be equipped with the rotary wheel device that medicine support can be driven to rotate so that capsule chamber falls into the puncture direction of piercing device on the body.The purpose of the invention is to overcome shortcoming of the prior art, there is provided and it is a kind of simple in structure, it is easy to use, it can once load the Diskus of multiple capsules.
Description
Technical field
The present invention relates to a kind of Diskus.
Background technology
From last century the mid-50, the inhalator of Charles Thiel inventions starts, people begin in asthma and
In the treatment of chronic obstructive disease of lung, using by medical treatment device of the inhaled drugs aerosol delivery to patient.
There is apparent advantage relative to administering mode, inhalation-type drug administrations such as oral and hypodermic injections.Due to human nasal
Chamber, bronchus and the mucomembranous surface of lung accumulate very big, a total of 23 bifurcateds of respiratory tract of human body, and adult's alveolar surface area can be high
Up to 140 square metres, alveolar wall is very thin, the densely covered a large amount of capillaries of surrounding.Drug particles can be glued with fast strikethrough alveolar wherein
Membrane tissue is directly entered blood circulation.It is small rapid-action, malicious with no intestines and stomach degradation, the first pass effect without liver, dosage
Side effect is low and suitable for advantages such as large biological molecule deliverings.Lung Sucked medicine is the lungs such as treatment asthma, chronic obstructive pneumonia
The optimal treatment mode of portion's disease, had also further expanded to treatment whole body property disease in recent years, such as diabetes, its market is huge
Greatly.
Existing suction apparatus have pressurized metered dose inhalers (Pressurized Metered Dose Inhaler,
PMDI), three kinds of sprayer (Nebulizer), Diskus (Dry Powder Inhaler, DPI) forms.PMDI needs to use
Propellant, although apply at present be it is environmental-friendly to hydrofluoroalkane of the atmospheric ozone layer without destruction as propellant,
But it still can bring greenhouse effect;And, it is necessary to which the appropriate cooperation that medicine ejection-patient sucks, otherwise inhales when using pMDI
It is very low to enter efficiency.Sprayer is the product that volume is big, non-portable, is generally only applicable to use in hospital or family.And DPI is not
Need propellant;Medicine disperses to be triggered by patient inspiration flow, and there is no cooperative effect;And large biological molecule is in dry powder
Under, its stability higher.Inhalation-type drug administration is more demanding to the aerodynamic force size of drug particles, 0.5-5 microns of aerodynamic force diameter
Between drug particles can effectively deposit to lower respiratory tract and alveolar etc., so as to effectively be absorbed by human body.More than 5 microns
Particle will deposit to oral cavity, trunnion and the upper respiratory tract;And the particle less than 0.5 micron, 90% will breathe out body with patient expiration
Outside.But the drug particles powder between 0.5-5 microns be usually easy to conglomeration, it is necessary to pharmaceutical engineering technology and inhalant it is excellent
Change design to improve the dispersiveness of drug particles.There is an important parameter when assessing the validity of mealy medicine at the time of inhalation
It is exactly fine granular ratio (Fine Particle Fraction, FPF), it is organic in the medicament ejected in its expression inhalator
The ratio in lung can be deposited to.In general, the ratio is defined as the particle fraction that aerodynamic diameter in medicament is less than 5 microns.
One medication amount for suction is generally less than 50 micrograms, is usually 25-50 micrograms.It is desirable to from inhalator
The dosage of sucking-off has higher uniformity, and for the medicine of predetermined close, the relative standard deviation (RSD) between each dosage is no
Should be more than 5%.So the medicine for needing to suck generally is made capsule by existing way.
Existing capsule Diskus is typically all single branch capsule-type, need to once be brought not to user with once changing
Just, the more capsule dry powder administration suction apparatus of existing a few moneys are there is also structure is relatively complicated, production cost relative to
Higher, suction is difficult, at the same existing more capsule Diskuses there is also the complicated filling glue of dampproof effect difference application method
Some defects of capsule inconvenience
So existing capsule Diskus is up for further perfect.
The content of the invention
The purpose of the invention is to overcome shortcoming of the prior art, there is provided and it is a kind of simple in structure, it is easy to use,
The Diskus of multiple capsules can once be loaded.
In order to achieve the above object, the present invention uses following scheme:
A kind of Diskus, includes main body, and suction nozzle is equipped with described main body one end, and energy is equipped with the main body
The medicine support of rotation, is equipped with several capsule chambers for being used to place capsule, being equipped with the main body to connect in the medicine support
The through hole of capsule chamber and suction nozzle, the piercing device for being placed on the indoor capsule of capsule can be pierced through on the body by being equipped with, in institute
State main body and be equipped with the rotary wheel device that medicine support can be driven to rotate so that capsule chamber falls into the puncture direction of piercing device.
A kind of Diskus as described above, it is characterised in that the piercing device includes sliding head, is sliding
Head one end is equipped with the pricker that can pierce through the capsule, is arranged on institute equipped with sliding slot, the slip head on the body
State in sliding slot.
A kind of Diskus as described above, it is characterised in that being equipped with the main body inner wall can reset slip head
Return unit.
A kind of Diskus as described above, it is characterised in that be equipped with the body easy to be placed into capsule chamber
The installation opening of capsule, is hinged with the housing that can close the installation opening on the body, and the piercing device is arranged on housing
On.
A kind of Diskus as described above, it is characterised in that the rotary wheel device includes driving runner, described
Driving runner is movably connected in main body by shaft, and the main body is stretched out on the driving runner top, in the medicine support periphery
Driving cog is equipped with, is equipped with sliding tooth on the driving runner, the sliding tooth is intermeshed with driving cog.
A kind of Diskus as described above, it is characterised in that filtering is equipped between the through hole and suction nozzle outlet end
Net.
A kind of Diskus as described above, it is characterised in that be arranged with dust cover in the suction nozzle outer wall.
A kind of Diskus as described above, it is characterised in that sequence corresponding with capsule chamber is equipped with the medicine support
Numeral, on the body equipped with count window.
A kind of Diskus as described above, it is characterised in that the medicine support includes turntable, and the capsule chamber is evenly distributed with
On the turntable, connection rotation axis is equipped with the turntable side, limiting stand is equipped with the outer wall of connection rotation axis end
Rank, on the body equipped with mounting hole, the main body at the mounting hole, which extends internally, connecting portion, and the mounting hole is set
In the connecting portion, spacing chuck is equipped with the connecting portion inner wall of end, the connection rotation axis is plugged on the installation
In hole, the limited step is fastened in the spacing chuck.
A kind of Diskus as described above, it is characterised in that be equipped with Decorative Cover in the installation outer end of hole.
In conclusion the present invention is relative to prior art its advantage:
The configuration of the present invention is simple, performance load multiple capsules, and when use only needs to stir driving runner, drives runner
Medicine support is driven to rotate, the capsule in medicine support turns to suitable position, then slides piercing device and pierce through capsule, and user is from suction
Just the dry powder in capsule can be sucked at mouth easily, using simple.
The present invention can be effectively moisture-proof, easy to use and inhalation power require it is small, can long-distance travel, go on business or hospital use.
Brief description of the drawings
Fig. 1 is one of schematic perspective view of the present invention;
Fig. 2 is the two of the schematic perspective view of the present invention;
Fig. 3 is the internal structure schematic diagram of the present invention;
Fig. 4 is the diagrammatic cross-section of the present invention.
Embodiment
The invention will be further described with embodiment for explanation below in conjunction with the accompanying drawings:
A kind of Diskus as shown in Figures 1 to 4, includes main body 1, and suction nozzle 2 is equipped with described 1 one end of main body,
The medicine support 3 that can be rotated is equipped with the main body 1, several capsule chambers 5 for being used to place capsule 4 are equipped with the medicine support 3,
Capsule chamber 5 and the through hole 6 of suction nozzle 2 can be connected by being equipped with the main body 1, be equipped with to pierce through in the main body 1 and be placed on glue
The piercing device 7 of capsule 4 in capsule room 5, being equipped with the main body 1 can drive medicine support 3 to rotate so that capsule chamber 5 falls into thorn
The rotary wheel device 8 in the puncture direction of penetrating device 7.
Heretofore described piercing device 7 includes sliding head 71, and institute can be pierced through by being equipped with 71 one end of head is slided
The pricker 72 of capsule 4 is stated, sliding slot 73 is equipped with the main body 1, the slip head 71 is arranged in the sliding slot 73.
Heretofore described slip head 71 includes slide 711, and the slide 711 is arranged in sliding slot 73,
73 bottom of sliding slot is equipped with the connection slot 712 of 1 inner cavity of connection main body, and skid resistance strip is equipped with 711 outer surface of slide
713, it is equipped with 711 inner surface of slide perpendicular to slide 711 and stretches into the connecting portion 714 in medicine support 3, the pricker 72
Set perpendicular to connecting portion 714, the through hole 6 is directed toward in 72 end of pricker.
The return unit 74 that can reset slip head 71 is equipped with the present invention in 1 inner wall of main body.It is heretofore described
Return unit 74 be tension spring, described tension spring one end is connected to 1 inner wall of main body, and the tension spring other end, which is connected to, slides head 71
On.Using process, when needing to pierce through the capsule of the top of through hole 6, need to only stir slip head 71 moves down pricker 72, pricker 72
Through the intercommunicating pore for being arranged on capsule chamber upper/lower terminal, it is inserted into capsule body, when slip head 71 loses external force, in tension spring
Under the action of, slide head 71 and reset the drive disengaging capsule of pricker 72, just form at least one hole slot on capsule body at this time, use
Dry powder in capsule just can be sucked suction nozzle 2 by person easily, so that throat is sucked, it is easy to use.
It is equipped with the present invention in the main body 1 easy to place the installation opening 101 of capsule 4 into capsule chamber 5, in the master
The housing 102 of the installation opening 101 can be closed by being hinged with body 1, and the piercing device 7 is set on housing 102.In the shell
Body 102 is equipped with easy to open the groove 1021 of housing 102.Capsule if desired is placed into capsule chamber 5 during use, is only needed
Groove 1021 is pulled, the upset of housing 102 is opened, capsule just can easily be put into capsule chamber 5, it is easy to use.
Heretofore described rotary wheel device 8 includes driving runner 81, and the driving runner 81 passes through the activity of shaft 82
It is connected in main body 1, the main body 1 is stretched out on 81 top of the driving runner, and driving cog 30 is equipped with 3 periphery of medicine support,
Sliding tooth 83 is equipped with the driving runner 81, the sliding tooth 83 is intermeshed with driving cog 30.
Heretofore described driving runner 81, which includes stretching out outside the main body 1, stirs runner 811, and the sliding tooth 83 is set
Put it is described stir runner 811 it is coaxial on.
Filter screen 9 is equipped with the present invention between 2 port of export of the through hole 6 and suction nozzle.Can there is filter screen 9 in the present invention
Effect filters the larger dry powder of particle diameter or the dry powder of conglomeration.
In the present invention dust cover 10 is arranged with 2 outer wall of suction nozzle.Dust cover 10 can effectively prevent the pollutants such as dust
Into in suction nozzle 2, ensure the clean hygiene of powder inhaler.
Sequence numeral 11 corresponding with capsule chamber 5 is equipped with the present invention in the medicine support 3, is equipped with the main body 1
Count window 12.Which time medication user can just can know that by observing count window 12, convenient, reliably.
Heretofore described medicine support 3 includes turntable 31, and the capsule chamber 5 is distributed on the turntable 31, at described turn
31 side of disk is equipped with connection rotation axis 32, limited step 33 is equipped with connection 32 end outer wall of rotation axis, in the main body 1
Mounting hole 103 is equipped with, the main body 1 at the mounting hole 103, which extends internally, connecting portion 104, and the mounting hole 103 is set
In the connecting portion 104, spacing chuck 105, connection 32 grafting of rotation axis are equipped with 104 inner wall of end of connecting portion
In the mounting hole 103, the limited step 33 is fastened in the spacing chuck 105.
In the present invention Decorative Cover 13 is equipped with 103 outer end of mounting hole.
Ten capsule chambers 5 are provided with the present invention in medicine support 3, in device capsule, it is only necessary to open housing 102, just
Capsule can be placed into capsule chamber 5, after placement, closes housing 102, stirring toggle switch appears in sequence number 1 in medicine support 3
In count window 12, the number used just can be very easily calculated using process, it is securely and reliably, easy to use.
The basic principle and main feature and advantages of the present invention of the present invention has been shown and described above.The skill of the industry
Art personnel it should be appreciated that the present invention is not limited to the above embodiments, the above embodiments and description only describe
The principle of the present invention, without departing from the spirit and scope of the present invention, various changes and modifications of the present invention are possible, these
Changes and improvements all fall within the protetion scope of the claimed invention.The claimed scope of the invention by appended claims and
Its equivalent thereof.
Claims (9)
- A kind of 1. Diskus, it is characterised in that:Include main body (1), suction nozzle (2) be equipped with the main body (1) one end, The medicine support (3) that can be rotated is equipped with the main body (1), several are equipped with the medicine support (3) and is used to place capsule (4) Capsule chamber (5), capsule chamber (5) and the through hole (6) of suction nozzle (2) can be connected by being equipped with the main body (1), in the main body (1) The piercing device (7) for the capsule (4) being placed in capsule chamber (5) can be pierced through by being equipped with, and being equipped with the main body (1) to drive Medicine support (3) rotates so that capsule chamber (5) falls into the rotary wheel device (8) in the puncture direction of piercing device (7), puncture dress Putting (7) includes sliding head (71), and the pricker (72) that can pierce through the capsule (4) is equipped with head (71) one end is slided, The main body (1) is equipped with sliding slot (73), and the slip head (71) is arranged in the sliding slot (73).
- 2. a kind of Diskus according to claim 1, it is characterised in that cunning can be made by being equipped with the main body (1) inner wall The return unit (74) that dynamic head (71) resets.
- 3. a kind of Diskus according to claim 1, it is characterised in that be equipped with and be easy to glue in the main body (1) The installation opening (101) of capsule (4) is placed in capsule room (5), the installation opening (101) can be closed by being hinged with the main body (1) Housing (102), the piercing device (7) is arranged on housing (102).
- 4. a kind of Diskus according to claim 1, it is characterised in that the rotary wheel device (8) includes driving Runner (81), the driving runner (81) are movably connected in main body (1) by shaft (82), described driving runner (81) top The main body (1) is stretched out, driving cog (30) is equipped with medicine support (3) periphery, is equipped with and drives on the driving runner (81) Moving teeth (83), the sliding tooth (83) are intermeshed with driving cog (30).
- 5. a kind of Diskus according to claim 1, it is characterised in that exported in the through hole (6) and suction nozzle (2) Filter screen (9) is equipped between end.
- 6. a kind of Diskus according to claim 1, it is characterised in that be arranged with the suction nozzle (2) outer wall dust-proof Cover (10).
- 7. a kind of Diskus according to claim 1, it is characterised in that be equipped with the medicine support (3) and capsule chamber (5) corresponding sequence is digital (11), and count window (12) is equipped with the main body (1).
- A kind of 8. Diskus according to claim 1, it is characterised in that the medicine support (3) includes turntable (31), The capsule chamber (5) is distributed on the turntable (31), and connection rotation axis (32) is equipped with the turntable (31) side, even Switch through moving axis (32) end outer wall and be equipped with limited step (33), mounting hole (103) is equipped with the main body (1), described The main body (1) at mounting hole (103) place, which extends internally, connecting portion (104), and the mounting hole (103) is arranged on the connecting portion (104) in, spacing chuck (105) is equipped with the connecting portion (104) inner wall of end, the connection rotation axis (32) is plugged on institute State in mounting hole (103), the limited step (33) is fastened on the spacing chuck (105).
- 9. a kind of Diskus according to claim 8, it is characterised in that be equipped with dress in the mounting hole (103) outer end Decorations cover (13).
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN201510466553.0A CN104984448B (en) | 2015-07-30 | 2015-07-30 | A kind of Diskus |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201510466553.0A CN104984448B (en) | 2015-07-30 | 2015-07-30 | A kind of Diskus |
Publications (2)
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CN104984448A CN104984448A (en) | 2015-10-21 |
CN104984448B true CN104984448B (en) | 2018-05-01 |
Family
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Family Applications (1)
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CN201510466553.0A Active CN104984448B (en) | 2015-07-30 | 2015-07-30 | A kind of Diskus |
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Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110354353B (en) * | 2019-07-28 | 2021-07-27 | 江门市中心医院 | Medical extrusion type dry powder suction device |
CN112237676B (en) * | 2020-10-16 | 2022-12-13 | 南京青龙水务有限公司 | External ointment applicator capable of avoiding cross infection |
CN114949483B (en) * | 2021-02-23 | 2024-02-20 | 苏州易合医药有限公司 | Dry powder inhaler and manufacturing method thereof |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0211595A2 (en) * | 1985-07-30 | 1987-02-25 | Glaxo Group Limited | Devices for administering medicaments to patients |
US4860740A (en) * | 1980-10-30 | 1989-08-29 | Riker Laboratories, Inc. | Powder inhalation device |
US5372128A (en) * | 1993-04-14 | 1994-12-13 | Habley Medical Technology Corporation | Fluidizing powder inhaler |
CN102481424A (en) * | 2009-07-07 | 2012-05-30 | 辉瑞有限公司 | Dose unit, pack of dose units and inhaler for inhalation of combination of drugs |
CN204890850U (en) * | 2015-07-30 | 2015-12-23 | 中山市美捷时包装制品有限公司 | Many capsules of wheel style type dry powder suction apparatus |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102004012971B4 (en) * | 2004-03-17 | 2006-01-12 | Josef Eckert | Inhaler, in particular powder inhaler |
-
2015
- 2015-07-30 CN CN201510466553.0A patent/CN104984448B/en active Active
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4860740A (en) * | 1980-10-30 | 1989-08-29 | Riker Laboratories, Inc. | Powder inhalation device |
EP0211595A2 (en) * | 1985-07-30 | 1987-02-25 | Glaxo Group Limited | Devices for administering medicaments to patients |
US5372128A (en) * | 1993-04-14 | 1994-12-13 | Habley Medical Technology Corporation | Fluidizing powder inhaler |
CN102481424A (en) * | 2009-07-07 | 2012-05-30 | 辉瑞有限公司 | Dose unit, pack of dose units and inhaler for inhalation of combination of drugs |
CN204890850U (en) * | 2015-07-30 | 2015-12-23 | 中山市美捷时包装制品有限公司 | Many capsules of wheel style type dry powder suction apparatus |
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Address after: No.21 Jiankang Road, Torch Development Zone, Zhongshan City, Guangdong Province 528400 Patentee after: Guangdong Meijieshi Holdings Co.,Ltd. Country or region after: China Address before: No.21 Jiankang Road, Torch Development Zone, Zhongshan City, Guangdong Province 528400 Patentee before: MAJESTY PACKAGING SYSTEMS Ltd. Country or region before: China |