CN104983395B - Intraocular pressure real-time measurement apparatus based on conjunctival sac pressure detecting and method - Google Patents

Intraocular pressure real-time measurement apparatus based on conjunctival sac pressure detecting and method Download PDF

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CN104983395B
CN104983395B CN201510260814.3A CN201510260814A CN104983395B CN 104983395 B CN104983395 B CN 104983395B CN 201510260814 A CN201510260814 A CN 201510260814A CN 104983395 B CN104983395 B CN 104983395B
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signal
pressure
air bag
intraocular pressure
real
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CN104983395A (en
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李贵刚
张虹
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Tongji Medical College of Huazhong University of Science and Technology
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Tongji Medical College of Huazhong University of Science and Technology
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Abstract

The present invention relates to a kind of intraocular pressure real-time measurement apparatus based on conjunctival sac pressure detecting and method, this device includes detection head and the signal receiver loading patients conjunctival's capsule;Described detection head includes air bag and the baroceptor being located in air bag and flexible PCB, and the air pressure in described air bag is normal atmosphere, and air bag contacts with eyeball, and is in pressured state;Described flexible PCB is used for sensing described air bag internal gas pressure and air pressure being converted to the signal of telecommunication sending;Signal receiver, for receiving the signal that described flexible PCB sends.The inventive method senses air bag because of the air pressure signal produced by intraocular pressure by pressure transducer in air bag, and sends after this air pressure signal is converted to the signal of telecommunication, and signal receiver is received the laggard signal processing of crossing of the signal of telecommunication and obtained the real-time intraocular pressure value of patient.Present configuration is simple, it is possible to detects that the intraocular pressure value of patient, beneficially doctor make therapeutic scheme in time in real time, automatically, improves therapeutic efficiency.

Description

Intraocular pressure real-time measurement apparatus based on conjunctival sac pressure detecting and method
Technical field
The present invention relates to the measurement of intraocular pressure, survey in particular to real-time intraocular pressure based on conjunctival sac pressure detecting Amount device and method.
Background technology
Glaucoma is second-biggest-in-the-world diseases causing blindness, raises with pathologic intraocular pressure, irreversibility optic nerve Atrophy, defect of visual field is characterized.In China, glaucoma sickness rate is 0.21%-1.64%, blind rate 10%-20%, is deputy irreversible blinding oculopathy.
Intraocular pressure is that eyeball content (aqueous humor, crystalline lens, vitreous body, blood) acts on unit volume The size of wall of eyeball pressure.Intraocular pressure has 24h day and night fluctuation, and intraocular pressure raises and day and night fluctuation for a long time Increase and will cause optic nerve ischemia, neurodegeneration, retina the picture signal changed can not be suitable Profit is delivered to brain occipital lobe visual centre, causes irreversibility defect of visual field.
Find and control intraocular pressure the most as early as possible, reduce intraocular pressure day and night fluctuation amplitude, be to slow down green light at present Ophthalmic continues the definite treatment means deteriorated.Therefore, it is achieved 24 hours measure intraocular pressure continuously is in early days The problem finding abnormal needed badly the solution of intraocular pressure, and it is little to realize 24 to lack reliable instrument and equipment at present Shi Lianxu measures intraocular pressure.
At present, traditional tonometry includes referring to survey method, direct ophthalmic measurement method and tonometer detection method. Due to accuracy and the impact of safety, refer to that survey method and the direct method of measurement are rarely needed in clinic.And Connect the instrument tonometer measuring intraocular pressure and become intraocular pressure survey owing to possessing feature accurate, noninvasive The requisite instrumentation of amount, conventional intraocular pressure in respect of: Goldmann planishing type tonometer,Collapse Formula tonometer, non-contact tonometer etc..But existing tonometer has a following deficiency: 1) portable performance Lowly, needing patient's timing repeatedly to hospital's repetition measurement intraocular pressure, process of measuring expends huge manpower financial capacity Resource.2) operation need to be completed by the ophthalmologist of specialty, measures process loaded down with trivial details.3) anesthetics is used Product or instrument contacts cornea, easily cause the coup injury of cornea.And these measuring instruments are all only capable of single Measure intraocular pressure, it is impossible to monitor the fluctuation of long-term intraocular pressure, thus easily fail to pinpoint a disease in diagnosis some early-stage glaucomas patient. And the method being capable of long term monitoring intraocular pressure at present needs underwent operative implanted sensor, this is a kind of invasive The operation of wound property, therefore limits its popularization and application.As: scleral band button tonometer, intraocular pressure sensor (the Carter.C.Collins.Miniature passive pressure transensor for such as tonometer implanting in the eye.IEEE transaction on bio-medical engineering.1967:4,14,2;P.-Jui.Chen.Implantable Wireless Intraocular Pressure Sensors.IEEE.2008;)
Therefore, it is badly in need of a kind of safety, accurate, seriality intraocular pressure monitoring device clinically, makes ophthalmology cure Life can more in early days, objective, make the diagnosis of glaucoma all sidedly, make invisible glaucoma patient with And anti-glaucoma surgery patient can accept in early days the most rationally, more effectively treat.
Summary of the invention
In order to overcome the above-mentioned weakness of existing intraocular pressure monitoring device, the present invention provides a kind of based on conjunctival sac The mode of pressure detecting measures intraocular pressure indirectly, the method be capable of safety, accurately, long-range, portable Intraocular pressure monitoring.
Realize the object of the invention and employed technical scheme comprise that a kind of intraocular pressure based on conjunctival sac pressure detecting is real Time measurement apparatus, this device includes loading the detection head of patients conjunctival's capsule and signal receiver;
Described detection head includes air bag and the baroceptor being located in air bag and flexible PCB, institute Stating the air pressure in air bag is normal atmosphere, and air bag contacts with eyeball, and is in pressured state;Described Flexible PCB is used for sensing described air bag internal gas pressure and air pressure being converted to the signal of telecommunication sending;
Signal receiver, for receiving the signal that described flexible PCB sends.
In technique scheme, type connector is carved in being respectively arranged at two ends with of described air bag, connects two After carving type connector, described balloon occlusion, and described flexible PCB switches on power.
Further, described flexible PCB includes:
Pressure transducer, for detecting the intraocular pressure value of air bag sensing;And
Processor, is converted to the signal of telecommunication for the intraocular pressure value detected by described pressure transducer;
Signal projector, is used for the described signal of telecommunication to emission.
In technique scheme, described intraocular pressure real-time measurement apparatus based on conjunctival sac pressure detecting is also Including:
Memorizer, for receiving and store the signal that described signal projector is launched.
In technique scheme, described intraocular pressure real-time measurement apparatus based on conjunctival sac pressure detecting is also Including:
Printer, is connected with described memorizer, the data in print memory.
Additionally, the present invention also provides for a kind of method being measured intraocular pressure by said apparatus in real time, the method Including:
Detection head is loaded measured's conjunctival sac, makes air bag contact with eyeball, and air bag is in pressurized shape State;
Testing the current intraocular pressure of measured with tonometer, obtain measured's current intraocular pressure value, this test value is Intraocular pressure reference value;
The atmospheric pressure value detected is converted to the signal of telecommunication and sends by the flexible PCB being located in air bag;
Signal receiver receives the signal of telecommunication that flexible PCB sends, and obtains intraocular pressure according to the signal of telecommunication Value, is corrected this intraocular pressure value according to reference value, thus obtains real-time intraocular pressure value.
Further, the omnidistance intraocular pressure wave pattern stored in memorizer is printed display by printer.
The inventive method senses air bag because of the gas produced by intraocular pressure by the pressure transducer in air bag Pressure signal, and send, after signal receiver receives the signal of telecommunication after this air pressure signal is converted to the signal of telecommunication Enter signal processing and obtain the real-time intraocular pressure value of patient.Present configuration is simple, it is possible in real time, automatically Intraocular pressure value patient being detected, beneficially doctor makes therapeutic scheme in time, improves therapeutic efficiency.
Accompanying drawing explanation
Fig. 1 is the structural representation of present invention intraocular pressure based on conjunctival sac pressure detecting real-time measurement apparatus.
Fig. 2 is that the use state of present invention intraocular pressure based on conjunctival sac pressure detecting real-time measurement apparatus is shown It is intended to.
Fig. 3 is the flow chart of present invention intraocular pressure based on conjunctival sac pressure detecting method for real-time measurement.
Detailed description of the invention
The present invention is described in further detail with specific embodiment below in conjunction with the accompanying drawings.
As it is shown in figure 1, present invention intraocular pressure based on conjunctival sac pressure detecting real-time measurement apparatus includes inspection Gauge head 1 and signal receiver.The structure of detection 1 is as it is shown in figure 1, include air bag 2, in air bag 2 Being provided with flexible PCB 3 and pressure transducer 4, pressure transducer 4 is connected with flexible PCB 3, pressure Force transducer 4 detects the air pressure in air bag, and the air pressure signal detected is transferred to flexible PCB 3. Type connector 5 is carved in being respectively arranged at two ends with of air bag 2, connect two carve type connector 5 after so that flexible The conductive switch 6 of circuit board 3 is connected, and air bag 2 is closed.Flexible circuit used by the present embodiment Plate 3 includes processor and signal emission module, and the air pressure signal that pressure transducer detects is turned by processor Be changed to the signal of telecommunication, signal emission module will conversion after the signal of telecommunication to emission.
Owing to air bag its internal pressure in its natural state is atmospheric pressure, now pressure transducer 4 nothing Output.It is in pressured state after air bag 2 loads conjunctival sac, as in figure 2 it is shown, pressure transducer 4 The pressure detected in air bag 2 is changed.When intraocular pressure changes, can change eyeball size and Hardness, and detect 1 and be relatively fixed due to the fixation by conjunctival sac, position, eyeball big Little and hardness change can produce different pressure to air bag 2, thus changes the gas within air bag 2 Pressure, now pressure transducer 4 just can detect the air pressure signal of transformation.
Signal receiver receives the signal of telecommunication that signal emission module is launched, and through signal processing, is pressed The force value corresponding to air pressure signal of force transducer detection.For the ease of storage data, signal receives Machine is also associated with memorizer, and memorizer receives the signal of signal projector transmitting and stores.For the ease of Medical personnel obtain the intraocular pressure information of patient immediately, and the present invention can also arrange a connection printer Computer, computer is also connected with memorizer, exports the data in memorizer to printer and carries out Print.
The process of intraocular pressure is measured in real time as shown in Figure 3 by above-mentioned intraocular pressure real-time measurement apparatus.
Type connector is carved at S1, connection detection 1 two ends, and the flexible PCB 3 in detection 1 is connected, And forming the detection air bag of closing, detection 1 i.e. enters duty, the at this moment pressure in air bag 2 Can be approximately normal atmosphere (An), the signal display current gas pressure received by signal receiver is zero.
S2, detection 1 being installed in measured's conjunctival sac, now air bag 2 contacts with eyeball, And it is in pressured state.
S3, due to air bag 2 pressurized, at this moment signal receiver should be shown as according to received signal The current intraocular pressure of measured.But due to by detection head installation site and measured's eyelid thickness, hardness etc. Factor affects, and individual physiological structure or the difference of detection head present position, and detection 1 can export Different intraocular pressure values, the current intraocular pressure value shown by receiver misfits with actual intraocular pressure value, at this moment needs The intraocular pressure value that third party's detection means to be used detection eyeball is current.
Therefore, this step tonometer measures the intraocular pressure value that eyeball 7 is current, by this tonometry value Be the equilibrium point of air bag internal gas pressure, using this equilibrium point as zero, rise when eyeball pressure or During decline, air bag internal gas pressure rises or falls therewith.
S4, being corrected according to the tonometry value detected in step S3, i.e. signal receiver is by eye Pressure measured value is as the datum mark of this detection process.
S5, pressure transducer detect different atmospheric pressure values and launch mould by the signal in detection 1 Block sends, and after signal receiver receives the sent signal of telecommunication, finally obtains through signal processing Real-time intraocular pressure value in different time sections.
The tonometry value that the real-time intraocular pressure value that signal receiver obtains deducts datum mark corresponding is patient Actual intraocular pressure value.
In 24 hours of actually detected process, detection 1 can be controlled by flexible PCB 3 every Within 5 minutes, submit one-time detection value, each duration 1 second to.All data all input stores preserve, and protect Deposit the time of each data receiver.Intraocular pressure value representated by each detected value by testing acquirement, this experiment number According to input computer, computer entered signal processing and calculated at the intraocular pressure detected by different times Value.
S6, the signal receiving signal receiver store, and computer is by defeated for the data in memorizer Go out to carry out omnidistance intraocular pressure wave pattern to printer and print display.
The present invention is not limited solely to above-mentioned specific embodiment, persons skilled in the art according to Example and accompanying drawing disclosure, can use other multiple detailed description of the invention to implement the present invention, because of This, the mentality of designing of every employing present invention and design structure, do some simply change or changes Design, both falls within the scope of protection of the invention.

Claims (5)

1. an intraocular pressure real-time measurement apparatus based on conjunctival sac pressure detecting, it is characterised in that: include Load detection head and the signal receiver of patients conjunctival's capsule;
Described detection head includes air bag and the baroceptor being located in air bag and flexible PCB, institute Stating the air pressure in air bag is normal atmosphere, and air bag contacts with eyeball, and is in pressured state;Described Flexible PCB is used for sensing described air bag internal gas pressure and air pressure being converted to the signal of telecommunication sending;
Signal receiver, for receiving the signal that described flexible PCB sends.
Intraocular pressure real-time measurement apparatus based on conjunctival sac pressure detecting the most according to claim 1, its Be characterised by: type connector is carved in being respectively arranged at two ends with of described air bag, connect two carve type connector after, Described balloon occlusion, and described flexible PCB switches on power.
Intraocular pressure real-time measurement apparatus based on conjunctival sac pressure detecting the most according to claim 1 or claim 2, It is characterized in that described flexible PCB includes:
Pressure transducer, for detecting the intraocular pressure value of air bag sensing;And
Processor, is converted to the signal of telecommunication for the intraocular pressure value detected by described pressure transducer;
Signal projector, is used for the described signal of telecommunication to emission.
Intraocular pressure real-time measurement apparatus based on conjunctival sac pressure detecting the most according to claim 3, its It is characterised by also including:
Memorizer, for receiving and store the signal that described signal projector is launched.
Intraocular pressure real-time measurement apparatus based on conjunctival sac pressure detecting the most according to claim 4, its It is characterised by also including:
Printer, is connected with described memorizer, the data in print memory.
CN201510260814.3A 2015-05-21 2015-05-21 Intraocular pressure real-time measurement apparatus based on conjunctival sac pressure detecting and method Active CN104983395B (en)

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CN108670193B (en) * 2018-07-02 2020-05-01 苏州兆乘四海通科技有限公司 Intraocular pressure tracking and measuring instrument
CN111361473A (en) * 2018-12-26 2020-07-03 北京奇虎科技有限公司 Safety prompt system and child safety seat
CN111381693A (en) * 2018-12-29 2020-07-07 广州幻境科技有限公司 Intelligent pressure sensing pen
CN112539868B (en) * 2019-09-23 2022-03-11 北京远见医疗技术发展有限责任公司 Method and equipment for detecting internal pressure and surface tangent tension of spherical capsule through surface
CN111166490B (en) * 2020-02-25 2020-11-27 青岛大学附属医院 Medical robot pressure detection method and medical robot

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US4089329A (en) * 1976-03-18 1978-05-16 University Of Utah Research Institute Noninvasive, continuous intraocular pressure monitor
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WO2009111726A2 (en) * 2008-03-06 2009-09-11 The Regents Of The University Of California Measuring outlflow resistance/facility of an eye
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