CN104958595A - Traditional Chinese medicine for treating peptic ulcer and preparation method thereof - Google Patents

Traditional Chinese medicine for treating peptic ulcer and preparation method thereof Download PDF

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CN104958595A
CN104958595A CN201510384874.6A CN201510384874A CN104958595A CN 104958595 A CN104958595 A CN 104958595A CN 201510384874 A CN201510384874 A CN 201510384874A CN 104958595 A CN104958595 A CN 104958595A
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张丽
丁敏
王桂珍
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Zheng Qi Bio Tech Ltd Jinan
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    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/58Meliaceae (Chinaberry or Mahogany family), e.g. Azadirachta (neem)
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/66Papaveraceae (Poppy family), e.g. bloodroot
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
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    • A61K36/888Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A61K36/8888Pinellia
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane

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Abstract

The invention discloses a traditional Chinese medicine for treating peptic ulcer and a preparation method thereof. The traditional Chinese medicine comprises the following raw materials in parts by weight: 30 to 40 parts of trichosanthes kirilowii maxim, 30 to 40 parts of caulis perillae, 30 to 40 parts of dried tangerine peel, 25 to 35 parts of rhizoma pinellinae praeparata, 25 to 35 parts of rhizoma corydalis, 25 to 35 parts of bamboo shavings, 20 to 25 parts of blood clam shell, 20 to 25 parts of hedyotis diffusa, 20 to 25 parts of cuttlebone, 20 to 25 parts of allium macrostemon bunge, 10 to 15 parts of earthworm, 10 to 15 parts of radix sophorae subprostratae, 10 to 15 parts of szechwan chinaberry fruit and 5 to 10 parts of catechu. The traditional Chinese medicine disclosed by the invention adopts pure traditional Chinese medicinal components and has the advantages of no side effect, high cure rate, good effect and low possibility of relapse; the preparation method is simple.

Description

A kind of Chinese medicine for the treatment of digestive system and ulcer and preparation method thereof
Technical field
The invention belongs to field of traditional Chinese, be specifically related to a kind of Chinese medicine for the treatment of digestive system and ulcer and preparation method thereof.
Background technology
Peptic ulcer (peptic ulcer, PU) is a kind of commonly encountered diseases of digestive system, mostly betides the duodenal chronic ulcer of harmonization of the stomach, also known as taste-blindness rate.Between local mucosa lesions factor and mucosa protection factor caused by disequilibrium, when damage factor enhancing or protection factor reduction, just ulcer can be there is.The clinical symptoms of ulcers can be improved at present to some extent for the Western medicine for the treatment of digestive system and ulcer, but due to side effect large, patient is difficult to tolerance, and easily recurs after drug withdrawal, does not filter out generally acknowledged medicine safely and effectively so far yet; Tcm clinical practice is taked the dialectical Therapeutic Method treated more, and common drug has Aucklandiae and Amomi stomach-calming ball, Zuojin Wan, XIANGSHA LIUJU WAN etc., but these medicines to there is the course for the treatment of long, take effect slow, the shortcomings such as DeGrain.
Summary of the invention
The present invention discloses a kind of safe and effective for solving the deficiencies in the prior art, Chinese medicine of the treatment digestive system and ulcer that curative effect is good and preparation method thereof.This medicine adopts pure Chinese medicine, has no side effect, and cure rate is high, and instant effect not easily recurs, and preparation method is simple.
Treat a Chinese medicine for digestive system and ulcer, main components in percentage by weight by weight:
The each 30-40 part of Fructus Trichosanthis, Caulis Perillae, Pericarpium Citri Reticulatae, each 25-35 part of Rhizoma Pinelliae Preparatum, Rhizoma Corydalis, Caulis Bambusae In Taenia, Concha Arcae, Herba Hedyotidis Diffusae, Endoconcha Sepiae, each 20-25 part of Bulbus Allii Macrostemonis, Pheretima, Radix Sophorae Tonkinensis, each 10-15 part of Fructus Toosendan, catechu 5-10 part.
As technique scheme further preferably, described Chinese herbal main component proportioning is by weight: each 30-35 part of Fructus Trichosanthis, Caulis Perillae, Pericarpium Citri Reticulatae, the each 25-30 part of Rhizoma Pinelliae Preparatum, Rhizoma Corydalis, Caulis Bambusae In Taenia, Concha Arcae, Herba Hedyotidis Diffusae, Endoconcha Sepiae, each 20-23 part of Bulbus Allii Macrostemonis, Pheretima, Radix Sophorae Tonkinensis, each 10-15 part of Fructus Toosendan, catechu 5-8 part.
Further optimization technique scheme, described Chinese herbal main component is joined best than by weight: each 32 parts of Fructus Trichosanthis, Caulis Perillae, Pericarpium Citri Reticulatae, each 25 parts of Rhizoma Pinelliae Preparatum, Rhizoma Corydalis, Caulis Bambusae In Taenia, Concha Arcae, Herba Hedyotidis Diffusae, Endoconcha Sepiae, each 23 parts of Bulbus Allii Macrostemonis, Pheretima, Radix Sophorae Tonkinensis, each 12 parts of Fructus Toosendan, 5 parts, catechu.
According to above technology preparation, concrete preparation method is as follows:
A, in proportion medical material Fructus Trichosanthis, Caulis Perillae, Pericarpium Citri Reticulatae, Rhizoma Pinelliae Preparatum, Rhizoma Corydalis, Caulis Bambusae In Taenia, Concha Arcae, Herba Hedyotidis Diffusae, Endoconcha Sepiae, Bulbus Allii Macrostemonis, Pheretima, Radix Sophorae Tonkinensis, catechu are added in marmite, add the cold water soak 60-90 minute of 6-7 times of weight, intense fire is decocted to boiling, slow fire boiling 60-90 minute, filters to obtain medicinal liquid a;
B, the water adding 3-5 times of weight to marmite carry out second time and decoct, and intense fire is decocted to boiling, adds in the medicinal liquid of boiling in proportion, slow fire boiling 60-90 minute, filter to obtain medicinal liquid b by Fructus Toosendan;
C, by medicinal liquid a and b mix homogeneously, obtain medicament.
The above-mentioned preparation method of further optimization, technological parameter is: soak time 60-70 minute; The slow fire fried time is 70-90 minute.
Fructus Toosendan does not need to soak, slow fire boiling after direct water seethes with excitement, this is because its effective ingredient decocts easy loss through soaking easily leaching for a long time, adds after therefore Fructus Toosendan not being needed to be immersed in second time decoction boiling.
Using method: this medicament is direct oral drugs, a 150ml, one day twice, general 6 days courses for the treatment of, serve on 4 courses for the treatment of.
Pharmacology analysis:
Fructus Trichosanthis is used for clearing away heat and eliminating phlegm, and relieving stuffiness of the chest by dispersing aggregation of pathogens, moisturizes laxation; It is vexed that Caulis Perillae is used for chest and diaphragm painful abdominal mass, gastralgia, and belch is vomitted; Pericarpium Citri Reticulatae cures mainly distension and fullness in the abdomen or pain, the dyspepsia of stagnation of QI in spleen and stomach; Gastric qi falls in Rhizoma Pinelliae Preparatum, eliminate the phlegm turbid, in and gastric acid, be conducive to eliminating ulcer edema; Rhizoma Corydalis has invigorates blood circulation, circulation of qi promoting, effect of pain relieving; Caulis Bambusae In Taenia is used for the treatment of cough due to lung-heat, dysphoria with smothery sensation is palpitated with fear, gastric heat is vomitted oh; Concha Arcae has the effect of expectorant blood stasis dispelling, hard masses softening and resolving, relieving gastric hyperacidity to alleviate stomachache; Herba Hedyotidis Diffusae antiphlogistic antibacterial, is conducive to killing helicobacter pylori, hepatic cholagogic, can prevent bile reflux; Endoconcha Sepiae is used for the treatment of belch pantothenic acid, eczema ulcer; Bulbus Allii Macrostemonis can treat gastrointestinal humidity hysteresis, dysentery, aid digestion and anti-diarrhea effect of being amusing; Pheretima anti-peptic ulcer; Radix Sophorae Tonkinensis gastric acid secretion inhibiting, repairs gastric ulcer; Fructus Toosendan cures mainly all pains of heat symptom-complex gastral cavity abdominal rib; Catechu expelling pus and promoting granulation, is conducive to convergence ulcer skin ulcer face and healing.Said medicine compatibility uses, synergism, thus the object reaching treatment.
The invention provides a kind of Chinese medicine for the treatment of digestive system and ulcer and preparation method thereof, solve taste empty, ulcer at the bottom of stomach, congestion, phlegm-damp disease.The selected natural Chinese medicines material of the present invention, medicine source is extensive, and price is low, safe and effective, convenient drug administration, short treating period, good effect, avirulence.
Detailed description of the invention
Embodiment 1
Treat a Chinese medicine for digestive system and ulcer, main components in percentage by weight is counted by weight:
Each 30 parts of Fructus Trichosanthis, Caulis Perillae, Pericarpium Citri Reticulatae, each 25 parts of Rhizoma Pinelliae Preparatum, Rhizoma Corydalis, Caulis Bambusae In Taenia, Concha Arcae, Herba Hedyotidis Diffusae, Endoconcha Sepiae, each 20 parts of Bulbus Allii Macrostemonis, Pheretima, Radix Sophorae Tonkinensis, each 10 parts of Fructus Toosendan, 5 parts, catechu.
According to above technology preparation, concrete preparation method is as follows:
A, in proportion medical material Fructus Trichosanthis, Caulis Perillae, Pericarpium Citri Reticulatae, Rhizoma Pinelliae Preparatum, Rhizoma Corydalis, Caulis Bambusae In Taenia, Concha Arcae, Herba Hedyotidis Diffusae, Endoconcha Sepiae, Bulbus Allii Macrostemonis, Pheretima, Radix Sophorae Tonkinensis, catechu are added in marmite, add the cold water soak 60 minutes of 6 times of weight, intense fire is decocted to boiling, slow fire boiling 60 minutes, filters to obtain medicinal liquid a;
B, the water adding 3 times of weight to marmite carry out second time and decoct, and intense fire is decocted to boiling, adds in the medicinal liquid of boiling in proportion, slow fire boiling 90 minutes, filter to obtain medicinal liquid b by Fructus Toosendan;
C, by medicinal liquid a and b mix homogeneously, obtain medicament.
Embodiment 2
Treat a Chinese medicine for digestive system and ulcer, main components in percentage by weight by weight:
Each 40 parts of Fructus Trichosanthis, Caulis Perillae, Pericarpium Citri Reticulatae, each 35 parts of Rhizoma Pinelliae Preparatum, Rhizoma Corydalis, Caulis Bambusae In Taenia, Concha Arcae, Herba Hedyotidis Diffusae, Endoconcha Sepiae, each 25 parts of Bulbus Allii Macrostemonis, Pheretima, Radix Sophorae Tonkinensis, each 15 parts of Fructus Toosendan, 10 parts, catechu.
According to above technology preparation, concrete preparation method is as follows:
A, in proportion medical material Fructus Trichosanthis, Caulis Perillae, Pericarpium Citri Reticulatae, Rhizoma Pinelliae Preparatum, Rhizoma Corydalis, Caulis Bambusae In Taenia, Concha Arcae, Herba Hedyotidis Diffusae, Endoconcha Sepiae, Bulbus Allii Macrostemonis, Pheretima, Radix Sophorae Tonkinensis, catechu are added in marmite, add the cold water soak 90 minutes of 7 times of weight, intense fire is decocted to boiling, slow fire boiling 90 minutes, filters to obtain medicinal liquid a;
B, the water adding 3-5 times of weight to marmite carry out second time and decoct, and intense fire is decocted to boiling, adds in the medicinal liquid of boiling in proportion, slow fire boiling 60 minutes, filter to obtain medicinal liquid b by Fructus Toosendan;
C, by medicinal liquid a and b mix homogeneously, obtain medicament.
Embodiment 3
Treat a Chinese medicine for digestive system and ulcer, main components in percentage by weight by weight:
Each 32 parts of Fructus Trichosanthis, Caulis Perillae, Pericarpium Citri Reticulatae, each 25 parts of Rhizoma Pinelliae Preparatum, Rhizoma Corydalis, Caulis Bambusae In Taenia, Concha Arcae, Herba Hedyotidis Diffusae, Endoconcha Sepiae, each 23 parts of Bulbus Allii Macrostemonis, Pheretima, Radix Sophorae Tonkinensis, each 12 parts of Fructus Toosendan, 5 parts, catechu.
According to above technology preparation, concrete preparation method is as follows:
A, in proportion medical material Fructus Trichosanthis, Caulis Perillae, Pericarpium Citri Reticulatae, Rhizoma Pinelliae Preparatum, Rhizoma Corydalis, Caulis Bambusae In Taenia, Concha Arcae, Herba Hedyotidis Diffusae, Endoconcha Sepiae, Bulbus Allii Macrostemonis, Pheretima, Radix Sophorae Tonkinensis, catechu are added in marmite, add the cold water soak 70 minutes of 6 times of weight, intense fire is decocted to boiling, slow fire boiling 70 minutes, filters to obtain medicinal liquid a;
B, the water adding 4 times of weight to marmite carry out second time and decoct, and intense fire is decocted to boiling, adds in the medicinal liquid of boiling in proportion, slow fire boiling 80 minutes, filter to obtain medicinal liquid b by Fructus Toosendan;
C, by medicinal liquid a and b mix homogeneously, obtain medicament.
Embodiment 4
Treat a Chinese medicine for digestive system and ulcer, main components in percentage by weight by weight:
Each 35 parts of Fructus Trichosanthis, Caulis Perillae, Pericarpium Citri Reticulatae, each 30 parts of Rhizoma Pinelliae Preparatum, Rhizoma Corydalis, Caulis Bambusae In Taenia, Concha Arcae, Herba Hedyotidis Diffusae, Endoconcha Sepiae, each 22 parts of Bulbus Allii Macrostemonis, Pheretima, Radix Sophorae Tonkinensis, each 13 parts of Fructus Toosendan, 8 parts, catechu.
According to above technology preparation, concrete preparation method is as follows:
A, in proportion medical material Fructus Trichosanthis, Caulis Perillae, Pericarpium Citri Reticulatae, Rhizoma Pinelliae Preparatum, Rhizoma Corydalis, Caulis Bambusae In Taenia, Concha Arcae, Herba Hedyotidis Diffusae, Endoconcha Sepiae, Bulbus Allii Macrostemonis, Pheretima, Radix Sophorae Tonkinensis, catechu are added in marmite, add the cold water soak 80 minutes of 7 times of weight, intense fire is decocted to boiling, slow fire boiling 90 minutes, filters to obtain medicinal liquid a;
B, the water adding 3-5 times of weight to marmite carry out second time and decoct, and intense fire is decocted to boiling, adds in the medicinal liquid of boiling in proportion, slow fire boiling 70 minutes, filter to obtain medicinal liquid b by Fructus Toosendan;
C, by medicinal liquid a and b mix homogeneously, obtain medicament.
Embodiment 5
Treat a Chinese medicine for digestive system and ulcer, main components in percentage by weight is counted by weight:
Each 36 parts of Fructus Trichosanthis, Caulis Perillae, Pericarpium Citri Reticulatae, each 32 parts of Rhizoma Pinelliae Preparatum, Rhizoma Corydalis, Caulis Bambusae In Taenia, Concha Arcae, Herba Hedyotidis Diffusae, Endoconcha Sepiae, each 22 parts of Bulbus Allii Macrostemonis, Pheretima, Radix Sophorae Tonkinensis, each 13 parts of Fructus Toosendan, 7 parts, catechu.
According to above technology preparation, concrete preparation method is as follows:
A, in proportion medical material Fructus Trichosanthis, Caulis Perillae, Pericarpium Citri Reticulatae, Rhizoma Pinelliae Preparatum, Rhizoma Corydalis, Caulis Bambusae In Taenia, Concha Arcae, Herba Hedyotidis Diffusae, Endoconcha Sepiae, Bulbus Allii Macrostemonis, Pheretima, Radix Sophorae Tonkinensis, catechu are added in marmite, add the cold water soak 70 minutes of 6 times of weight, intense fire is decocted to boiling, slow fire boiling 80 minutes, filters to obtain medicinal liquid a;
B, the water adding 3-5 times of weight to marmite carry out second time and decoct, and intense fire is decocted to boiling, adds in the medicinal liquid of boiling in proportion, slow fire boiling 90 minutes, filter to obtain medicinal liquid b by Fructus Toosendan;
C, by medicinal liquid a and b mix homogeneously, obtain medicament.
The result of clinical observation of the present invention is as follows:
Recovery from illness: clinical symptoms and sign disappear completely or substantially disappear;
Effective: clinical symptoms and sign major part take a turn for the better or be clearly better;
Invalid; Clinical symptoms and sign are all not improved, symptom as front, DeGrain.
Therapeutic outcome: totally 50 routine patients, every embodiment each 10 people take, and take medicine after the course for the treatment of, symptom takes a turn for the better all to some extent, and after 4 courses for the treatment of of taking medicine, 36 people's recoveries from illness, 9 people are effective, and 3 people are effective, and 2 people are invalid, and total effective rate is 96%.

Claims (5)

1. Chinese medicine for the treatment of digestive system and ulcer and preparation method thereof, is characterized in that: main components in percentage by weight is counted by weight:
The each 30-40 part of Fructus Trichosanthis, Caulis Perillae, Pericarpium Citri Reticulatae, each 25-35 part of Rhizoma Pinelliae Preparatum, Rhizoma Corydalis, Caulis Bambusae In Taenia, Concha Arcae, Herba Hedyotidis Diffusae, Endoconcha Sepiae, each 20-25 part of Bulbus Allii Macrostemonis, Pheretima, Radix Sophorae Tonkinensis, each 10-15 part of Fructus Toosendan, catechu 5-10 part;
Its preparation method:
A, in proportion medical material Fructus Trichosanthis, Caulis Perillae, Pericarpium Citri Reticulatae, Rhizoma Pinelliae Preparatum, Rhizoma Corydalis, Caulis Bambusae In Taenia, Concha Arcae, Herba Hedyotidis Diffusae, Endoconcha Sepiae, Bulbus Allii Macrostemonis, Pheretima, Radix Sophorae Tonkinensis, catechu are added in marmite, add the cold water soak 60-90 minute of 6-7 times of weight, intense fire is decocted to boiling, slow fire boiling 60-90 minute, filters to obtain medicinal liquid a;
B, the water adding 3-5 times of weight to marmite carry out second time and decoct, and intense fire is decocted to boiling, adds in the medicinal liquid of boiling in proportion, slow fire boiling 60-90 minute, filter to obtain medicinal liquid b by Fructus Toosendan;
C, by medicinal liquid a and b mix homogeneously, obtain medicament.
2. a kind of Chinese medicine for the treatment of digestive system and ulcer according to claim 1 and preparation method thereof, it is characterized in that: main components in percentage by weight is counted by weight: each 30-35 part of Fructus Trichosanthis, Caulis Perillae, Pericarpium Citri Reticulatae, the each 25-30 part of Rhizoma Pinelliae Preparatum, Rhizoma Corydalis, Caulis Bambusae In Taenia, Concha Arcae, Herba Hedyotidis Diffusae, Endoconcha Sepiae, each 20-23 part of Bulbus Allii Macrostemonis, Pheretima, Radix Sophorae Tonkinensis, each 10-15 part of Fructus Toosendan, catechu 5-8 part.
3. a kind of Chinese medicine for the treatment of digestive system and ulcer according to claim 1 and preparation method thereof, it is characterized in that: main components in percentage by weight is counted by weight: each 32 parts of Fructus Trichosanthis, Caulis Perillae, Pericarpium Citri Reticulatae, each 25 parts of Rhizoma Pinelliae Preparatum, Rhizoma Corydalis, Caulis Bambusae In Taenia, Concha Arcae, Herba Hedyotidis Diffusae, Endoconcha Sepiae, each 23 parts of Bulbus Allii Macrostemonis, Pheretima, Radix Sophorae Tonkinensis, each 12 parts of Fructus Toosendan, 5 parts, catechu.
4. treat a preparation method for the Chinese medicine of digestive system and ulcer, it is characterized in that:
A, in proportion medical material Fructus Trichosanthis, Caulis Perillae, Pericarpium Citri Reticulatae, Rhizoma Pinelliae Preparatum, Rhizoma Corydalis, Caulis Bambusae In Taenia, Concha Arcae, Herba Hedyotidis Diffusae, Endoconcha Sepiae, Bulbus Allii Macrostemonis, Pheretima, Radix Sophorae Tonkinensis, catechu are added in marmite, add the cold water soak 60-90 minute of 6-7 times of weight, intense fire is decocted to boiling, slow fire boiling 60-90 minute, filters to obtain medicinal liquid a;
B, the water adding 3-5 times of weight to marmite carry out second time and decoct, and intense fire is decocted to boiling, adds in the medicinal liquid of boiling in proportion, slow fire boiling 60-90 minute, filter to obtain medicinal liquid b by Fructus Toosendan;
C, by medicinal liquid a and b mix homogeneously, obtain medicament.
5. a kind of Chinese medicine for the treatment of digestive system and ulcer according to claim 1, is characterized in that: soak time 60-70 minute; Twice slow fire fried time is 70-90 minute.
CN201510384874.6A 2015-06-30 2015-06-30 Traditional Chinese medicine for treating peptic ulcer and preparation method thereof Pending CN104958595A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017000449A1 (en) * 2015-06-30 2017-01-05 济南正骐生物科技有限公司 Chinese medicine for treating digestive system ulceration and preparation method thereof

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