CN104940693A - Dendrobium officinale traditional Chinese medicine composition capable of lowering three highs and preparation method of dendrobium officinale traditional Chinese medicine composition - Google Patents
Dendrobium officinale traditional Chinese medicine composition capable of lowering three highs and preparation method of dendrobium officinale traditional Chinese medicine composition Download PDFInfo
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Abstract
The invention discloses a dendrobium officinale traditional Chinese medicine composition capable of lowering three highs and a preparation method of the dendrobium officinale traditional Chinese medicine composition and relates to the technical field of traditional Chinese medicine. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 40-50 parts of baikal skullcap root, 20-30 parts of abrus herb, 6-12 parts of hemp seeds, 6-12 parts of black sesame, 6-12 parts of dendrobium officinale, 4-6 parts of wolfberry fruits, 4-6 parts of Szechwan chinaberry fruits, 4-6 parts of laver, 4-6 parts of kudzu vine root, 2-4 parts of onions, 2-4 parts of corn stigma and 2-4 parts of sea buckthorn. The 12 Chinese herbal medicine selected act together to achieve the health care effects of clearing heat and removing toxicity, dissipating heat and relaxing the bowels, dispersing the depressed liver-qi and alleviating pain, expanding blood vessels and reducing blood viscosity; and the dendrobium officinale traditional Chinese medicine composition is very suitable for taking everyday for the treatment and prevention heath care of three highs.
Description
Technical field
The present invention relates to technical field of Chinese medicines, especially relate to a kind of Herba Dendrobii Chinese medicine composition falling three-hypers and preparation method thereof.
Background technology
" three-hypers " refers to hyperglycemia, hyperlipidemia, hypertension.Along with the change of growth in the living standard and rhythm of life, modern people's dietary structure is increasingly meticulous, the quantity of feed meat, protide increases greatly, and the ratio of fruit and vegetable then reduces relatively, causes diet structure unreasonable, fat intake is too much, add that labor intensity is general not high, working environment relative comfort, therefore, the metabolic syndromes such as the hyperlipidemia based on obesity, hypertension, hyperglycemia rise year by year, and more and more in rejuvenation trend." three-hypers disease " long term can concurrent cardiovascular and cerebrovascular disease, is the health and lives of cardiovascular and cerebrovascular disease arch-criminal, the serious threat mankind, and anti-" three-hypers " has been the thing that Modern human populations is badly in need of doing.
At present, the patient of " three-hypers disease " is generally by medication treatment or adjustment, and general therapeutic " three-hypers ", based on Western medicine, can control hypertension, hyperlipidemia, hyperglycemia effectively.But Western medicine, while effectively regulating three-hypers, often produces some untoward reaction, such as: diuretic depressor major side effects is one low (hypokalemia), three-hypers (raising blood fat, blood glucose, blood uric acid).Drug side effect has become impact one of long-term continued treatment and the major issue of quality of life, must correctly be familiar with and deal carefully with.
Since ancient times, what the traditional Chinese medical science just had " integration of edible and medicinal herbs " says, and always emphasizes health preserving, and the essence of integration of edible and medicinal herbs, medicine rises from diet in other words, and diet is the good medicine promoted health and cured diseases.Modern plants technology development in recent years, people are applied to medicine to natural plants, the research of field of health care food becomes focus.Herba Dendrobii is the holy product of YIN nourishing be described as first of " China nine large Herba mesonae chinensis ", records in the Compendium of Material Medica of Ming Dynasty's Li Shizhen (1518-1593 A.D.): the Herba Dendrobii eliminating impediment therapeutic method to keep the adverse QI flowing downwards, mend internal organs asthenia and win thin, and reinforcing YIN-essence benefit is smart.Clothes of a specified duration, thick the intestines and stomach, never sufficient in benefit.Carry out gastric qi, longue meat, Fructus Alpiniae Oxyphyllae, except frightened, made light of one's life by commiting suicide and is prolonged life.Modern medicine study proves, Herba Dendrobii can significantly improve body's immunity, has nourishing the stomach to promote the production of body fluid, enriching yin and nourishing kidney, improving eyesight are kept fit, the effect such as anoxia enduring, resisting fatigue, antitumor, anticancer, radioprotective, defying age, blood vessel dilating.
Summary of the invention
Goal of the invention of the present invention is: for above-mentioned Problems existing, a kind of Herba Dendrobii Chinese medicine composition falling three-hypers and preparation method thereof is provided, 12 kinds of Chinese herbal medicine selected by the present invention, the health-care effect of heat-clearing and toxic substances removing, expelling pathogenic heat to loosen the bowels, dispersing the depressed liver-QI for alleviating pain, blood sugar lowering, blood vessel dilating, reduction blood viscosity is played in combined effect, is applicable to very much dailyly taking treatment for three-hypers and prevention and health care.
For achieving the above object, the technical scheme of employing is as follows in the present invention:
Falling a Herba Dendrobii Chinese medicine composition for three-hypers, is be made up of the crude drug of following weight portion: Radix Scutellariae 40-50 part, Herba Abri 20-30 part, Fructus Cannabis 6-12 part, Semen Sesami Nigrum 6-12 part, Herba Dendrobii 6-12 part, Fructus Lycii 4-6 part, Fructus Toosendan 4-6 part, Thallus Porphyrae 4-6 part, Radix Puerariae 4-6 part, Bulbus Allii Cepae 2-4 part, Stigma Maydis 2-4 part, Fructus Hippophae 2-4 part.
Further, described in the Herba Dendrobii Chinese medicine composition of three-hypers falls, be made up of the crude drug of following weight portion: Radix Scutellariae 42-48 part, Herba Abri 22-26 part, Fructus Cannabis 8-10 part, Semen Sesami Nigrum 8-10 part, Herba Dendrobii 8-10 part, Fructus Lycii 5-6 part, Fructus Toosendan 5-6 part, Thallus Porphyrae 4-5 part, Radix Puerariae 4-5 part, Bulbus Allii Cepae 2-3 part, Stigma Maydis 2-3 part, Fructus Hippophae 2-3 part.
Further, described in the Herba Dendrobii Chinese medicine composition of three-hypers falls, be made up of the raw material of following weight portion: Radix Scutellariae 45 parts, Herba Abri 25 parts, Fructus Cannabis 9 parts, Semen Sesami Nigrum 9 parts, Herba Dendrobii 9 parts, Fructus Lycii 5 parts, Fructus Toosendan 5 parts, Thallus Porphyrae 5 parts, Radix Puerariae 4.5 parts, Bulbus Allii Cepae 2.5 parts, Stigma Maydis 2.5 parts, Fructus Hippophae 2.5 parts.
Above-mentioned preparation method of falling the Herba Dendrobii Chinese medicine composition of three-hypers, comprises the following steps:
(1) Radix Scutellariae is taken according to proportioning, Herba Abri, Fructus Cannabis, Semen Sesami Nigrum, Fructus Lycii, Fructus Toosendan, Thallus Porphyrae, Radix Puerariae, Bulbus Allii Cepae, Stigma Maydis, then above-mentioned 11 kinds of raw materials are smashed to pieces by Fructus Hippophae, with water backflow, add 11 kinds of crude drug weight 8-15 water heating and refluxing extraction doubly 2-3 time, each extraction 1-3 hour at every turn, filter, merging filtrate, filtrate is cooled to 30-50 DEG C, being concentrated into room temperature measuring relative density is 1.05-1.20, and centrifugal remove impurity is for subsequent use;
(2) smash to pieces after fresh for Herba Dendrobii bar being cleaned, with the alcohol reflux of Herba Dendrobii fresh bar weight 8-15 times amount, extraction time is 2-3 time, each 1-3 hour, the concentration of ethanol is 50-65%, filters, reclaim ethanol, it is 1.05-1.20 that filtrate concentrated solution is cooled to 25 DEG C of mensuration relative densities, and centrifugal remove impurity is for subsequent use;
(3) merged by the concentrated solution of step (1) and step (2) gained, mix homogeneously, be evaporated to the extractum that relative density of medicine liquid is 1.15, spraying dry, obtains Chinese medicine composition.
Above-mentioned Chinese medicine composition can form preparation with pharmaceutically acceptable carrier.Described preparation is tablet, granule or oral liquid.
Effect of each component used in the present invention is as follows:
Radix Scutellariae, bitter in the mouth, cold in nature.Return lung, gallbladder, spleen, large intestine, small intestine meridian.There is heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive, effect of blood pressure lowering.For hygropyrexia, fever disease in summer vomiting and nausea uncomfortable in chest, damp and hot feeling of fullness, dysentery, jaundice, cough due to lung-heat, high hot excessive thirst, heat in blood tells nosebleed, carbuncle sore tumefacting virus, frequent fetal movement.
Herba Abri: sweet in the mouth, micro-hardship is cool.There is dampness removing jaundice eliminating, heat-clearing and toxic substances removing, effect of dispersing the depressed liver-QI for alleviating pain.Herba Abri blade contains glycyrrhizin, has nourishing YIN to lower pathogenic fire, supplementing QI for promoting the production of body fluid, antiviral, relieving constipation of invigorating blood circulation, dispersing the stagnated liver-QI for regulating the stomach effect.
Fructus Cannabis: sweet in the mouth, property is put down, and returns spleen, stomach, large intestine channel.There is the function of loosening bowel to relieve constipation, nourishing.For blood deficiency and depleted fluid, dryness of the intestine constipation.
Semen Sesami Nigrum: there is invigorating the liver and kidney, moistening five ZANG-organs, physical strength profiting, longue meat, fill out the effect of brains, can be used for treating dizzy, early whitening of beard and hair, alopecia, soreness of the waist and knees, limbs fatigue caused by Liver and kidney asthenia of essence and blood, walk with difficulty, the dry dried and withered hairs of deficient five internal organs, skin, the disease such as dryness of the intestine constipation, effect in blacking hair and nourishing face, celebrated especially.
Fructus Lycii: sweet in the mouth; Property is put down.There is nourishing the liver; Nourishing kidney; Effect of lung moistening.Have and reduce blood glucose, lipotropy, and can atherosclerosis.
Fructus Toosendan: cold in nature, bitter in the mouth.Soothing liver-QI promoting the circulation of QI to relieve pain, anthelmintic.For the breast side of body, abdominal distention, colic, abdominal pain due to worm stagnation.
Thallus Porphyrae: cool in nature is sweet in the mouth, salty.Resolving phlegm and softening hard masses, clearing away heat and promoting diuresis, the kidney invigorating are nourished heart.Thallus Porphyrae contains abundant Porphyra Polysaccharide, protein, fat, carotene, vitamin etc., and Porphyra Polysaccharide wherein can show reduction fasting glucose.
Herba Dendrobii: can significantly improve body's immunity, has nourishing the stomach to promote the production of body fluid, enriching yin and nourishing kidney, improving eyesight is kept fit, the effect such as anoxia enduring, resisting fatigue, antitumor, anticancer, radioprotective, defying age, blood vessel dilating.Herba Dendrobii can make moist sering, and blood vessel dilating, thus blood circulation promoting, improve blood stasis symptom, reduces cholesterolemia and triglyceride, improves hdl level.
Radix Puerariae: sweet, pungent, property is put down.There is expelling pathogenic factors from muscles for reducing heat; Deliver and examine; Promoting the production of body fluid to quench thirst; Effect of yang invigorating antidiarrheal.The total flavones of Radix Puerariae and puerarin can improve the oxygen metabolism of cardiac muscle, produce beneficial effect to myocardial metabolism, and energy blood vessel dilating, improves microcirculation simultaneously, reduce vascular resistance, blood flow is increased, thus available control myocardial ischemia, myocardial infarction, arrhythmia, hypertension, the diseases such as arteriosclerosis.Puerarin significantly falls hypoglycemic effect in addition, and the flavone compound contained by Radix Puerariae has effect for reducing blood fat, can reduce serum cholesterol, reduces oily three esters, is used for the treatment of hyperglycemia, hyperlipidemic conditions, has significant curative effect.
In addition, Radix Puerariae extraction flavonoid substances is combined with Folium Mori extract deoxynojirimycin and forms a kind of novel substance---and wash clear sugar element (cics) of pancreas, there is effects such as falling three-hypers, blood fat, antiinflammatory.
Bulbus Allii Cepae containing odoriferous substance mercaptan, disulphide, trisulfide, several amino acids etc., has higher medical value, can blood fat reducing, anti-platelet aggregation, antiinflammatory, relieving asthma, also have good hypoglycemic activity.
Stigma Maydis: sweet in the mouth, light, property is put down.There is inducing diuresis to remove edema; Effect of liver heat removing function of gallbladder promoting.Control hypertension, diabetes, edema, dribbling urination, jaundice, cholecystitis, cholelithiasis, galactostasis.Stigma Maydis has dilating effect to peripheral vessel, so also have hypotensive effect.
Containing 7 kinds of Endospermum chinense Benth. materials such as isorhamnetin and glucoside, Quercetin, nimbecetin in sea buckthorn fruit, there is cough-relieving, the usefulness of eliminating the phlegm, expanding coronary vasodilator, reducing cholesterol of relievining asthma.
In sum, owing to have employed technique scheme, the invention has the beneficial effects as follows: the present invention passes on the elite of the traditional Chinese medical science, combine effect of Chinese herbal medicine that 12 tastes have blood sugar lowering, blood fat reducing, blood pressure lowering, health tea prescription pharmacology of the present invention is: heat-clearing and toxic substances removing, dispersing the depressed liver-QI for alleviating pain, blood sugar lowering, blood vessel dilating, reduction blood viscosity, the attachment of dredging vascellum wall, improves immunity, regulate the function of each internal organs of human body, thus reach the object of falling three-hypers.Above-mentioned scientific formula reasonable compatibility, follow " monarch, minister, help, make " principle, be monarch drug with Radix Scutellariae, there is effect of eliminating fire and detoxication, blood pressure lowering, with Herba Abri, Fructus Lycii for ministerial drug, there is reinforcement heat-clearing and toxic substances removing, effect of dispersing the depressed liver-QI for alleviating pain, help with energy expelling pathogenic heat to loosen the bowels, the Fructus Cannabis of body endotoxin removing, Semen Sesami Nigrum, can the Radix Puerariae of blood vessel dilating, Stigma Maydis, Fructus Hippophae, can hypoglycemic Herba Dendrobii, Thallus Porphyrae and Folium Mori, the Bulbus Allii Cepae of blood viscosity can be reduced, there is the effect of obviously falling three-hypers.12 kinds of drug combinations in this prescription, whole reasonable recipe, rigorous, jointly play the health-care effect of heat-clearing and toxic substances removing, expelling pathogenic heat to loosen the bowels, dispersing the depressed liver-QI for alleviating pain, blood sugar lowering, blood vessel dilating, reduction blood viscosity, be applicable to very much dailyly taking treatment for three-hypers and prevention and health care.
Detailed description of the invention
Below by specific embodiment, the invention will be further described with test.
One, embodiment is prepared
Embodiment 1
Falling a Herba Dendrobii Chinese medicine composition for three-hypers, is be made up of the crude drug of following weight portion: Radix Scutellariae 40 parts, Herba Abri 30 parts, Fructus Cannabis 6 parts, Semen Sesami Nigrum 12 parts, Herba Dendrobii 12 parts, Fructus Lycii 6 parts, Fructus Toosendan 4 parts, Thallus Porphyrae 4 parts, Radix Puerariae 6 parts, Bulbus Allii Cepae 4 parts, Stigma Maydis 4 parts, Fructus Hippophae 2 parts.
Adopt following method to prepare above-mentioned Chinese medicine composition, comprise the following steps:
(1) Radix Scutellariae is taken according to proportioning, Herba Abri, Fructus Cannabis, Semen Sesami Nigrum, Fructus Lycii, Fructus Toosendan, Thallus Porphyrae, Radix Puerariae, Bulbus Allii Cepae, Stigma Maydis, then above-mentioned 11 kinds of raw materials are smashed to pieces by Fructus Hippophae, with water backflow, add the water heating and refluxing extraction 2 times of 11 kinds of crude drug weight 8 times at every turn, to extract 1 hour at every turn, filter, merging filtrate, filtrate is cooled to 30 DEG C, being concentrated into room temperature measuring relative density is 1.05-1.10, and centrifugal remove impurity is for subsequent use;
(2) smash to pieces after fresh for Herba Dendrobii bar being cleaned, with the alcohol reflux of Herba Dendrobii fresh bar weight 8 times amount, extraction time is 2 times, each 1 hour, the concentration of ethanol was 50%, filtered, reclaim ethanol, it is 1.05-1.10 that filtrate concentrated solution is cooled to 25 DEG C of mensuration relative densities, and centrifugal remove impurity is for subsequent use;
(3) merged by the concentrated solution of step (1) and step (2) gained, mix homogeneously, be evaporated to the extractum that relative density of medicine liquid is 1.15, spraying dry, obtains Chinese medicine composition.
By above-mentioned Chinese medicine composition together with medically acceptable adjuvant, make tablet according to a conventional method.
Embodiment 2
Falling a Herba Dendrobii Chinese medicine composition for three-hypers, is be made up of the crude drug of following weight portion: Radix Scutellariae 42 parts, Herba Abri 22 parts, Fructus Cannabis 8 parts, Semen Sesami Nigrum 8 parts, Herba Dendrobii 8 parts, Fructus Lycii 5 parts, Fructus Toosendan 5 parts, Thallus Porphyrae 4 parts, Radix Puerariae 4 parts, Bulbus Allii Cepae 2 parts, Stigma Maydis 2 parts, Fructus Hippophae 2 parts.
Adopt following method to prepare above-mentioned Chinese medicine composition, comprise the following steps:
(1) Radix Scutellariae is taken according to proportioning, Herba Abri, Fructus Cannabis, Semen Sesami Nigrum, Fructus Lycii, Fructus Toosendan, Thallus Porphyrae, Radix Puerariae, Bulbus Allii Cepae, Stigma Maydis, then above-mentioned 11 kinds of raw materials are smashed to pieces by Fructus Hippophae, with water backflow, add the water heating and refluxing extraction 3 times of 11 kinds of crude drug weight 15 times at every turn, to extract 3 hours at every turn, filter, merging filtrate, filtrate is cooled to 50 DEG C, being concentrated into room temperature measuring relative density is 1.10-1.20, and centrifugal remove impurity is for subsequent use;
(2) smash to pieces after fresh for Herba Dendrobii bar being cleaned, with the alcohol reflux of Herba Dendrobii fresh bar weight 15 times amount, extraction time is 3 times, each 3 hours, the concentration of ethanol was 65%, filtered, reclaim ethanol, it is 1.10-1.20 that filtrate concentrated solution is cooled to 25 DEG C of mensuration relative densities, and centrifugal remove impurity is for subsequent use;
(3) merged by the concentrated solution of step (1) and step (2) gained, mix homogeneously, be evaporated to the extractum that relative density of medicine liquid is 1.15, spraying dry, obtains Chinese medicine composition.
By above-mentioned Chinese medicine composition together with medically acceptable adjuvant, make granule according to a conventional method.
Embodiment 3
Falling a Herba Dendrobii Chinese medicine composition for three-hypers, is be made up of the raw material of following weight portion: Radix Scutellariae 45 parts, Herba Abri 25 parts, Fructus Cannabis 9 parts, Semen Sesami Nigrum 9 parts, Herba Dendrobii 9 parts, Fructus Lycii 5 parts, Fructus Toosendan 5 parts, Thallus Porphyrae 5 parts, Radix Puerariae 4.5 parts, Bulbus Allii Cepae 2.5 parts, Stigma Maydis 2.5 parts, Fructus Hippophae 2.5 parts.
The method identical with embodiment 1 is adopted to carry out making to obtain Chinese medicine composition.By above-mentioned Chinese medicine composition together with medically acceptable adjuvant, make oral liquid according to a conventional method.
Embodiment 4
Falling a Herba Dendrobii Chinese medicine composition for three-hypers, is be made up of the crude drug of following weight portion: Radix Scutellariae 50 parts, Herba Abri 20 parts, Fructus Cannabis 12 parts, Semen Sesami Nigrum 6 parts, Herba Dendrobii 6 parts, Fructus Lycii 4 parts, Fructus Toosendan 6 parts, Thallus Porphyrae 6 parts, Radix Puerariae 4 parts, Bulbus Allii Cepae 2 parts, Stigma Maydis 2 parts, Fructus Hippophae 4 parts.
The method identical with embodiment 2 is adopted to carry out making to obtain Chinese medicine composition.By above-mentioned Chinese medicine composition together with medically acceptable adjuvant, make oral liquid according to a conventional method.
Embodiment 5
Falling a Herba Dendrobii Chinese medicine composition for three-hypers, is be made up of the crude drug of following weight portion: Radix Scutellariae 48 parts, Herba Abri 26 parts, Fructus Cannabis 10 parts, Semen Sesami Nigrum 10 parts, Herba Dendrobii 10 parts, Fructus Lycii 6 parts, Fructus Toosendan 6 parts, Thallus Porphyrae 5 parts, Radix Puerariae 5 parts, Bulbus Allii Cepae 3 parts, Stigma Maydis 3 parts, Fructus Hippophae 3 parts.
The method identical with embodiment 1 is adopted to carry out making to obtain Chinese medicine composition.By above-mentioned Chinese medicine composition together with medically acceptable adjuvant, make oral liquid according to a conventional method.
Two, toxicity test
Get Kunming mouse 40, body weight 20-24g, male and female dual-purpose, be divided into two groups, often organize 20, wherein one group is normal amount test group, and another group is super quantity test group.The medication of normal amount group is 2mg/10g, and excess group is 4mg/10g, and administering mode is administration by gavage administration, and every day, sooner or later respectively once serve on one week, every day observed medication reaction.Result shows: the behavior of each group mice is without exception, and without poisoning symptom, appetite, feces are all without exception, general signs well, show health tea of the present invention safely, have no side effect.
Three, clinical observation material
The clinical observation material of medicine of the present invention
1, statistics: accept outpatient service obesity, three-hypers Metabolic Syndrome Patients 210 example for medical treatment, wherein man 106 example, female 94 example, age 40-50 year 54 examples, 51-60 year 71 examples, 61-70 year 69 examples, more than 70 years old 16 is routine, course of disease 1-10.
2, diagnostic criteria:
The clinical symptoms of 210 routine patients is obesity, dizziness, headache, nose heave dizzy, weak, breathe hard, uncomfortable in chest, numb limbs and tense tendons, palpitation and insomnia, susceptible to lose temper due to restlessness, chest and hypochondrium etc., sequal of cerebrovascular diseases patient speech disorder, facial paralysis, extremity are unsuccessful.
3, mode is taken:
Twice daily, each serving medicine in, Chinese medicine composition content is 0.3-0.4g, and two months is a course for the treatment of, serve on 2-3 the course for the treatment of.
4, efficacy assessment standard:
Effective: patients symptomatic disappears, body constitution recovers normal, follows up a case by regular visits to half a year without recidivist;
Take a turn for the better: patient body recovers normal substantially, and body constitution progressively takes a turn for the better;
Invalid: not reach improvement standard person.
5, therapeutic effect:
Hyperlipemia: in 210 routine patients, 94 examples are effective, serum cholesterol, triglyceride, high density lipoprotein three indexs within normal range, the transference cures such as sensation of oppression over the chest with shortness of breath, numb limbs and tense tendons, dizzy nose heave, abundant expectoration mouth are sticky.104 examples take a turn for the better, and three indexs are close to normal, and symptom disappears substantially.Clinical symptoms is improved greatly, and invalid 12 examples, total effective rate is 94.3%.
Hypertension: in 210 routine patients, 98 examples are effective, blood pressure stabilization within normal range more than 1 year, headache is dizzy, cardio palmus shape disappears.104 examples take a turn for the better, and blood pressure is close to normal, and clinical symptoms disappears substantially, and 8 examples are invalid, and total effective rate is 96.2%.
Hyperglycemia: in 210 routine patients, 86 examples are effective, fasting glucose <6.2mmo1/L, after meal 2 hours blood glucose <7.3mmol/L, clinical symptoms aching pain in waist and back, limb fiber crops limb pain, dry mouth and throat, weak, breathe hard, spontaneous sweating, thirst and liking drink, stool unite disappear.89 examples take a turn for the better, and fasting glucose <7.2mmo1/L, after meal 2 hours blood glucose 8.3mmo1/L, symptom disappears substantially.19 examples progressively take a turn for the better, fasting glucose <8.3mmo1/L, after meal 2 hours blood glucose <10mmo1/L, and partial symptoms disappears, and invalid 16 examples, total effective rate is 92.4%.
Four, model case:
1, Zhu, man, 58 years old, people from Nanning.Hypertension more than 1 year, blood pressure 182/92mmHg, fasting glucose 8.3mmol/L during discovery, face, extremity edema.Through taking Chinese medicine composition of the present invention 2 months, the transference cures such as face, extremity edema disease, blood pressure is steady, and remains within the scope of 125mmHg/75mmHg, and fasting glucose was also down in normal range.
2, Liu so-and-so, female, 54 years old, Guiping, Guangxi people from city.Hyperlipidemia more than 5 years, often occur the symptom such as headache, dizziness, blood pressure is 156mmHg/95mmHg, headache syndromes recurrent exerbation.Through taking Chinese medicine composition of the present invention, and stop using other all blood pressure lowerings, fat-reducing medicament after 3 months, blood pressure normally remains on 125mmHg/85mmHg.
3, the summer so-and-so, man, 50 years old, people from Yulin City of Guangxi Zhuang Autonomous.Hypertension more than 8 years, during discovery, hypertension is 183mmHg/91mmHg, and every day, oral nifedipine slow-release sheet 10mg*2 was just controlled, through taking Chinese medicine composition of the present invention, and stop using other all depressor after 6 months, blood pressure remains within the scope of 135mmHg/83mmHg.
The present invention is not limited to aforesaid detailed description of the invention.The present invention expands to any new feature of disclosing in this manual or any combination newly, and the step of the arbitrary new method disclosed or process or any combination newly.
Claims (6)
1. fall a Herba Dendrobii Chinese medicine composition for three-hypers, it is characterized in that being made up of the crude drug of following weight portion: Radix Scutellariae 40-50 part, Herba Abri 20-30 part, Fructus Cannabis 6-12 part, Semen Sesami Nigrum 6-12 part, Herba Dendrobii 6-12 part, Fructus Lycii 4-6 part, Fructus Toosendan 4-6 part, Thallus Porphyrae 4-6 part, Radix Puerariae 4-6 part, Bulbus Allii Cepae 2-4 part, Stigma Maydis 2-4 part, Fructus Hippophae 2-4 part.
2. a kind of Herba Dendrobii Chinese medicine composition falling three-hypers according to claim 1, it is characterized in that being made up of the crude drug of following weight portion: Radix Scutellariae 42-48 part, Herba Abri 22-26 part, Fructus Cannabis 8-10 part, Semen Sesami Nigrum 8-10 part, Herba Dendrobii 8-10 part, Fructus Lycii 5-6 part, Fructus Toosendan 5-6 part, Thallus Porphyrae 4-5 part, Radix Puerariae 4-5 part, Bulbus Allii Cepae 2-3 part, Stigma Maydis 2-3 part, Fructus Hippophae 2-3 part.
3. a kind of Herba Dendrobii Chinese medicine composition falling three-hypers according to claim 1, it is characterized in that being made up of the raw material of following weight portion: Radix Scutellariae 45 parts, Herba Abri 25 parts, Fructus Cannabis 9 parts, Semen Sesami Nigrum 9 parts, Herba Dendrobii 9 parts, Fructus Lycii 5 parts, Fructus Toosendan 5 parts, Thallus Porphyrae 5 parts, Radix Puerariae 4.5 parts, Bulbus Allii Cepae 2.5 parts, Stigma Maydis 2.5 parts, Fructus Hippophae 2.5 parts.
4. fall a preparation method for the Herba Dendrobii Chinese medicine composition of three-hypers, it is characterized in that comprising the following steps:
(1) Radix Scutellariae is taken according to proportioning, Herba Abri, Fructus Cannabis, Semen Sesami Nigrum, Fructus Lycii, Fructus Toosendan, Thallus Porphyrae, Radix Puerariae, Bulbus Allii Cepae, Stigma Maydis, then above-mentioned 11 kinds of raw materials are smashed to pieces by Fructus Hippophae, with water backflow, add 11 kinds of crude drug weight 8-15 water heating and refluxing extraction doubly 2-3 time, each extraction 1-3 hour at every turn, filter, merging filtrate, filtrate is cooled to 30-50 DEG C, being concentrated into room temperature measuring relative density is 1.05-1.20, and centrifugal remove impurity is for subsequent use;
(2) smash to pieces after fresh for Herba Dendrobii bar being cleaned, with the alcohol reflux of Herba Dendrobii fresh bar weight 8-15 times amount, extraction time is 2-3 time, each 1-3 hour, the concentration of ethanol is 50-65%, filters, reclaim ethanol, it is 1.05-1.20 that filtrate concentrated solution is cooled to 25 DEG C of mensuration relative densities, and centrifugal remove impurity is for subsequent use;
(3) merged by the concentrated solution of step (1) and step (2) gained, mix homogeneously, be evaporated to the extractum that relative density of medicine liquid is 1.15, spraying dry, obtains Chinese medicine composition.
5., containing a kind of preparation falling the Herba Dendrobii Chinese medicine composition of three-hypers described in any one of claim 1-3, it is characterized in that: be made up of the Chinese medicine composition described in any one of claim 1-3 and pharmaceutically acceptable carrier.
6. a kind of preparation falling the Herba Dendrobii Chinese medicine composition of three-hypers according to claim 5, is characterized in that: described preparation is tablet, granule or oral liquid.
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| CN201510372595.8A Pending CN104940693A (en) | 2015-06-29 | 2015-06-29 | Dendrobium officinale traditional Chinese medicine composition capable of lowering three highs and preparation method of dendrobium officinale traditional Chinese medicine composition |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105902867A (en) * | 2016-06-14 | 2016-08-31 | 西安力邦制药有限公司 | Plant medicine composition for reducing hyperlipidemia, hypertension and hyperglycemia and preparation method thereof |
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| US20040076641A1 (en) * | 2002-10-15 | 2004-04-22 | Timothy Kershenstine | Herbal dietary supplement |
| CN1742626A (en) * | 2005-09-17 | 2006-03-08 | 张志祥 | Sea-buckthorn licorice tablet and preparing technology |
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Application publication date: 20150930 |