CN104906220B - A kind of Chinese medicine for treating herpes zoster and herpes simplex keratitis - Google Patents
A kind of Chinese medicine for treating herpes zoster and herpes simplex keratitis Download PDFInfo
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Abstract
The present invention relates to treatment herpes zoster and the Chinese medicine of herpes simplex keratitis, the medication of herpes zoster and herpes simplex keratitis can be effectively solved the problems, such as, its technical scheme solved is made up of the material medicine of following weight meter：The 12g of the coptis 8, the 7g of rheum officinale 5, the 17g of radix scutellariae 13, the 17g of chrysanthemum 13, the 35g of cicada slough 25, windproof 10 14g, the 17g of the seed of feather cockscomb 13, the 17g of Radix Angelicae Sinensis 13, the 14g of peach kernel 10, the 12g of safflower 8, the 7g of scorpio 5, the 14g of earthworm 10 and the 7g of radix glycyrrhizae 5, abundant raw material of the present invention, it is cheap, there is removing dampness and detoxicating, heat-clearing improving eyesight, remove obstruction in channels to relieve pain, effective for treatment herpes zoster ophthalmicus and herpes simplex keratitis, good effect, drug safety, is to treat the innovation on herpes zoster and herpes simplex keratitis medicine.
Description
Technical field
It is particularly a kind of to treat in herpes zoster and herpes simplex keratitis the present invention relates to field of medicaments
Medicine.
Background technology
Herpes simplex keratitis and herpes zoster virus keratitis are two kinds of most common viral keratitis.
Wherein the herpes simplex keratitis incidence of disease accounts for the first place of keratonosus, is most common ulcer of the cornea.Viral keratitis is disease
Poison infection causes, the immune complexity illness in eye with inflammatory reaction participation, corneal damage and ocular institutional framework, and its incidence of disease is year by year
Rise.Its similar traditional Chinese medical science " dendritic keratitis " " keratomalacia " " mixed nebula, interstitial keratitis ", is, because of diseases caused by external factors ailment said due to cold or exposure, to hold under the arm raw thin on thermalization fire, blackening eyeball
Starlet screen is with puckery pain, photophobia, the illness in eye shed tears, and deeply development, can form scar ocular, is damaged eyesight.The disease often has bright
Aobvious irritated eyes, such as photophobia, shed tears, ache.Viral keratitis, the course of disease is often longer.With the progress of the course of disease,
Can often occur together uveitis, or even iridocyclitis, hypopyon, or secondary glaucoma occur, be relatively conventional
One of diseases causing blindness.And do not treat the medicine of herpes zoster ophthalmicus and herpes simplex keratitis determined curative effect on the market at present
Thing, therefore, the problem of improvement on treatment herpes zoster and herpes simplex keratitis medicine is current urgent need to resolve.
The content of the invention
For above-mentioned situation, to solve the defect of prior art, the purpose of the present invention is just to provide one kind and treats banding blister
The Chinese medicine of rash and herpes simplex keratitis, can effectively solve the medication of herpes zoster and herpes simplex keratitis
Problem.
Theoretical according to traditional Chinese medicine and pharmacy, herpes zoster and herpes simplex keratitis belong to the traditional Chinese medical science " dendritic keratitis " category.Member
Ni Weide writes《Former machine opens micro-》（1370 Christian eras）Just have that " patient has this number card, or does not take medicine, or wrongly takes medicine, and screen must to this disease
Give birth to therewith.Screen such as cloud and mist, silky cataract, screen such as gradations marked on the beam of steelyard.Screen such as gradations marked on the beam of steelyard person, or a bit, or three or four points, and tens of points that arrive.Screen
Such as blind nut person, be that disease is not gone long, control not as method, extremely arrive " description.Control suitable removing dampness and detoxicating, heat-clearing improving eyesight, remove obstruction in channels to relieve pain
Based on, accordingly, the technical scheme that the present invention is solved is made up of the material medicine of following weight meter：Coptis 8-12g, rheum officinale 5-
7g, radix scutellariae 13-17g, chrysanthemum 13-17g, cicada slough 25-35g, windproof 10-14g, seed of feather cockscomb 13-17g, Radix Angelicae Sinensis 13-17g, peach kernel
10-14g, safflower 8-12g, scorpio 5-7g, earthworm 10-14g and radix glycyrrhizae 5-7g, in use, adding water to submerge for the first time, soak 30-
60min, intense fire is fried boiling, then is cooked by slow fire 30min, filtering, obtains first time decocting liquid, second of dregs of a decoction adds water submergence, fried by intense fire
Boiling, then 30min is cooked by slow fire, with absorbent cotton filter 23, second of decocting liquid is obtained, is precipitated 3 hours, is taken supernatant, wash eye, eye droppings.
Abundant raw material of the present invention, it is cheap, there is removing dampness and detoxicating, heat-clearing improving eyesight, remove obstruction in channels to relieve pain, effective for
Herpes zoster ophthalmicus and herpes simplex keratitis, good effect, drug safety are treated, is treatment herpes zoster and herpes simplex virus
Innovation on property keratitis medicine.
Embodiment
The embodiment to the present invention is described in further detail with reference to embodiments.
Embodiment 1
The present invention in the specific implementation, can be made up of the material medicine of following weight meter：Coptis 9g, rheum officinale 5g, radix scutellariae
14g, chrysanthemum 14g, cicada slough 26g, windproof 11g, seed of feather cockscomb 14g, Radix Angelicae Sinensis 14g, peach kernel 11g, safflower 9g, scorpio 5g, earthworm 11g and
Radix glycyrrhizae 5g.
Embodiment 2
The present invention in the specific implementation, can also be made up of the material medicine of following weight meter：Coptis 10g, rheum officinale 6g, radix scutellariae
15g, chrysanthemum 15g, cicada slough 30g, windproof 12g, seed of feather cockscomb 15g, Radix Angelicae Sinensis 15g, peach kernel 12g, safflower 10g, scorpio 6g, earthworm 12g
With radix glycyrrhizae 6g.
Embodiment 3
The present invention in the specific implementation, can also be made up of the material medicine of following weight meter：Coptis 11g, rheum officinale 7g, radix scutellariae
16g, chrysanthemum 16g, cicada slough 34g, windproof 13g, seed of feather cockscomb 16g, Radix Angelicae Sinensis 16g, peach kernel 13g, safflower 11g, scorpio 7g, earthworm 13g
With radix glycyrrhizae 7g.
In prescription of the present invention：It is main ingredient, coptis bitter, cold in nature, heat-clearing and damp-drying drug, purging intense heat and detonicating with the coptis.《Book on Chinese herbal medicine is through hundred kinds
Record》Cloud：" all medicines can the person of drying must the gain of heat, be able to can not must dry except hot person, only the coptis can with bitter eliminating dampness, with cold except heat, at one stroke two
, god is not in this ".《The antiviral antibacterial action research of Chinese medicine》Say " coptis to 1 and herpes simplex types 2 virus have it is antiviral make
With." rheum officinale, taste bitter and cold, heat-clearing and damp-drying drug, purging intense heat and detonicating, the carbuncle that disappears, which dissipates, to be swollen, and the stasis of blood is stimulated the menstrual flow then.《Book on Chinese herbal medicine is newly organized》Say：" rheum officinale bitter,
Gas, which is trembled with fear ... pushes away Chen Zhixin, leads hemostasis, Roll phlegm prolongs, and breaks wei knot, and scattered heavily fortified point is poly-, and relieve the pain pain, loses ulcer heat toxin, subsides a swelling swollen, all respectively such as
God." two medicines all bitter-cold herbs expelling heats.But effect is not quite similar, coptis clearing away heat-damp and expelling toxic material, kind keep.Rheum officinale smell is deep, and purging intense heat is led to
Just, removing pattogenic heat from the blood and toxic material from the body, is apt to descending.Two medicine phases must be to use, and one, which walks one, keeps, and the purge heat power of removing toxic substances of fall fire increases.Therefore the two is monarch with it
Medicine.Radix scutellariae, bitter cold, bitter energy eliminating dampness, trembling with fear can heat-clearing.Can principal drug assistance heat-clearing solution eliminating dampness removing toxic substances power.Chrysanthemum, sweet-bitter flavor, cold nature.
Return lung, Liver Channel.Chrysanthemum energy dispelling wind, heat-clearing, improving eyesight, removing toxic substances.《Herbal justice》：" all main advocation catharsis of all flowers, only chrysanthemum, which is then taken the photograph, to be received
Decline, energy soothing the liver fire puts out interior wind, presses down the perverse and unreasonable manner of wood gas ".Cicada slough, clear heat with drugs of sweet flavour and cold nature floats clearly surname dissipate, clear dispelling wind heat, improving eyesight Tui Medical.
With the energy dispelling wind and heat from the body of chrysanthemum 5.It can strengthen and clear liver and improve vision.Chrysanthemum and cicada slough 5 are with being ophthalmology herbal pair.It is windproof, pungent, sweet,
Warm.Enter liver, the spleen channel.For the good medicine of wind-dispelling.The power for sharing dispelling wind clearing damp with chrysanthemum strengthens.The seed of feather cockscomb, it is bitter, it is slightly cold.Enter Liver Channel.Dispel
Wind-heat, clearing away the liver-fire, improving eyesight.《Haigoushen》：" liver heat toxin dotting punch is controlled, red barrier blue cataract swells.” 《The southern regions of the Yunnan Province book on Chinese herbal medicine》：" improving eyesight.Control
The puckery difficulty of tear is opened, and nebula hides eyeball ".Radix Angelicae Sinensis, acrid-sweet flavor is warm-natured.The thoughts of returning home, liver, the spleen channel.Benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturize laxation.
Peach kernel, it is bitter, sweet, it is mild-natured.Enter the heart, liver, large intestine channel.Blood system can be entered and blood stasis dispersing and fresh blood promoting, its property of medicine relaxes and pure, is cut down without high profit gram
Disadvantage thus for the blood-breaking row stasis of blood good medicine.Safflower, it is pungent, warm-natured.Enter the heart, Liver Channel.The pungent scattered temperature of this product is led to, can invigorate blood circulation, dissolving stasis
Analgesic.Peach kernel is used with safflower 5, is mutually promoted, and invigorate blood circulation, stasis eliminatings give birth to the power enhancing of new, swelling and pain relieving.Upper eight taste shares it
For ministerial drug.Scorpio, it is sweet, pungent, flat.Enter Liver Channel.Wind dispelling spasmolysis, removing toxicity for detumescence.Property it is kind drive away alter, remove obstruction in channels to relieve pain.Earthworm, it is salty, cold.
Enter spleen, stomach, liver and kidney channel.Clearing heat for calming endogenous wind, treatment numbness of stimulating the menstrual flow.This product is salty-cold, and the descending drop of property is let out and is apt to walk to alter.The use of two medicine 5 can strengthen
The power that clearing heat, releasing toxin, removing swelling is removed obstruction in channels to relieve pain, is adjutant with it.Radix glycyrrhizae coordinating the drug actions of a prescription is to make.
Above-mentioned component science, reasonable compatibility, are supported mutually, effective for treatment herpes zoster and herpes simplex keratitis angle
Film is scorching, and good effect, drug safety has no toxic side effect, and curative effect is stable, safe and reliable, and has obtained fully proving through experiment, relevant
Experimental data is as follows：
One, general information
2010~2013 years clinic cases in case history source.200, wherein male 108, women 92.40~49 years old persons
9 people, 50~59 years old people of person 58,60~69 years old people of person 86,70~79 years old people of person 47.60~70 years old person's incidence of disease highests.Treatment group
170；Control group 30.
Two, case selection standards
1. inclusive criteria：Reference《Eye, OtorhinolaryngologicDiseases Diseases diagnostic criteria》And《Chinese medical disease Standardization of diagnosis and curative effect》、
《Clinical disease diagnosis and curative effect judging standard》Identified diagnostic criteria is determined：1. the skin with ophthalmic branch of trigeminal nerve distributed area
On there is bleb and deposit or occupy its sequela, skin damaged is not past center line；Or have whole body heating, lymphoglandulae auriculares anteriores enlargement, lip or
The virus infection medical history such as skin bleb.2. corneal lesion, can involve epithelium, matrix or form ulcer；Cornea fluorescent staining is to circle
Shape spot or dendroid sign；Can with ocular pain, photophobia, shed tears, conjunctival congestion or merge sclerotitis, corpus ciliare choroideae
It is scorching.
2. exclusion standard：1st, gestation, women breast-feeding their children;2nd, there is allergies person;3rd, angiocarpy, liver, kidney and hematopoiesis are associated with
The severe primary disease such as system, mental patient；4th, keratitis caused by non-herpes simplex virus and herpes zoster virus;
5th, it is associated with the patient of other eye disease medical histories;6th, generate heat:Body temperature is higher than 38.5 DEG C；7th, it is all not meet inclusive criteria, do not press
Provide medication, it is impossible to judge that curative effect or data be not congruent and affect the treatment and security judgement person.
Three, therapeutic schemes
Treatment group：Decoction of the present invention（Also known as coptis chrysanthemum cicada soup）, head, which is decocted, to take orally, and two decoct secondary with absorbent cotton filter 23, and precipitation 3 is small
When, take clear liquid medicine to wash eye, eye droppings, day 3 times, it is early, middle and late it is each once, one portion per day recipe quantity 2 weeks is 1 course for the treatment of, 2 courses for the treatment of
Observe curative effect.
Specifically decoction is：Material medicine is mixed, added water to submerge, 30-60min is soaked, intense fire is fried boiling, then slow fire
Decoct 30min, filtering obtains first time decocting liquid into Chinese medicinal decoction, decoct it is once interior take, the dregs of a decoction add water submergence, and intense fire is fried boiling, then literary
Fire decocts 30min, with absorbent cotton filter 23, obtains second of decocting liquid, precipitates 3 hours, take supernatant, wash eye, eye droppings, 3 times a day,
It is early, middle and late it is each once, one day is one.
Control group：Acyclovir slice for oral administration, a 0.2g（2）, 3 times a day.Aciclovir eye drop point 3 times daily.2
Week is 1 course for the treatment of.2 courses for the treatment of observe curative effect.
Four, efficacy assessment standards
Issued with reference to State Administration of Traditional Chinese Medicine《Disease of tcm Standardization of diagnosis and curative effect》With《Clinical disease diagnosis and curative effect
Criterion》The criterion of therapeutical effect assert determines following standard.
Cure：Conjunctival congestion oedema disappears, and the multiple dendroid infiltration of corneal epithelium disappears, and kerato-iridocyclitis disappears
Lose, photophobia shed tears symptom disappearance, corneal fluorescein dyeing be negative；
Take a turn for the better：The slight congested mitigation of conjunctiva, the multiple dendroid infiltration of corneal epithelium mitigates, and kerato-iridocyclitis subtracts
Gently, photophobia is shed tears symptom mitigation, and cornea fluorescence dyes a little weakly positive；
It is invalid：Conjunctiva is substantially congested, and the multiple dendroid infiltration of corneal epithelium and kerato-iridocyclitis are without improvement, angle
Film fluorescent staining is positive, and inflammation is not controlled or lesion is aggravated.
Five, statistical procedures
By above-mentioned therapeutic scheme, to clinical definite, the patient with herpes zoster ophthalmicus and herpes simplex keratitis controls
Treat, treatment group 170, cure：149, take a turn for the better：It is 15, invalid：6, total effective rate is 96.47%.Control group 30, is controlled
More：13, take a turn for the better：It is 6, invalid：11.Total effective rate is 63.47%.Treatment group is compared with control group, * P ＜ 0.05, * * P
＜ 0.01, difference is statistically significant, shows invention traditional Chinese herbal decoction treatment herpes zoster ophthalmicus and herpes simplex keratitis effect
Fruit significantly, has reached clinical treatment purpose, and treatment group is over the course for the treatment of, has no adverse reaction.
1 two groups of patient clinical comparitive studies of table [n (%)]
| Number of cases | Cure | Take a turn for the better | It is invalid | Total effective rate % |
| 170 | 149 | 15 | 6 | 96.47% |
| 30 | 13 | 6 | 11 | 63.3% |
For more detailed description treatment, the curative effect situation of model case given below and treatment：
Case 1（Herpes zoster virus keratitis）
Zhang, man, 67 years old.
The first visit date：On 2 23rd, 2007.
Main suit：Right eye photophobia, shed tears, ache more than January.
Medical history：Feel right eye pain in late January in patient in 2007, put a little medicament for the eyes treatments, invalid and pain is aggravated, eye
Eyelid is red and swollen and has beading sample blister, i.e., to hospital therapy, examine on inspection as herpes zoster virus keratitis.After find papebral conjunctiva
Also have 1-2 blisters, i.e., in the hospitalize, but photophobia, shed tears, pain symptom is not apparent from mitigating, while with blurred vision,
Overburden for patients ' psychological, fears that aggravation can cause blindness etc..Introduced by patient to our hospital.
Tcm diagnosis：Eye She Dan.
Doctor trained in Western medicine is diagnosed：Right eye herpes zoster virus keratitis.
Take and wash eye orally with traditional Chinese herbal decoction of the present invention, be within 2 weeks a course for the treatment of.During medication, taboo drinks, marine product and
Hot food.
This example patient, the treatment through for oral administration and external application, the state of an illness is controlled quickly, and the course for the treatment of of medication 1 is then recovered.
Case 2（Herpes zoster virus keratitis, herpes zoster ophthalmicus post herpetic neuralgia half a year）
Lee, man, 34 years old.
The first visit date：On June 9th, 2007.
Main suit：Right eye redness, burning pain, sour and astringent companion's right face pain half a year.
Medical history：Patient is in feeling that right eye and right side facial pain are uncomfortable before half a year, right side eye socket and right Head And Face after a few days
Occur grain of rice size bleb, inflamed eyes, burning pain, it is sour and astringent, itch, be diagnosed as herpes zoster ophthalmicus, right eye in local hospital
Herpes zoster virus keratitis, instils through antiviral class medical intravenous and treats, and symptom has mitigated after two weeks, but right eye portion
Still rubescent, sour and astringent, pain of itching does not improve through traditional Chinese and western medicine, acupuncture and moxibustion therapy.Multi-party seek medical advice knows that undergraduate course treats this disease and has special effect, with next
It is medical.Look into patient's spirit not good enough, expression pain, the slight swelling of right eyelid, conjunctival congestion, corneal fluorescein sodium dyes visible branch
Shape is coloured.Patient feels that eye is sour and astringent, hurt like hell, it is impossible to open eyes, red tongue body, and tongue body is slightly fat big, thin lingual fur, pulse condition chord number.
Tcm diagnosis：Eye She Dan pains.
Doctor trained in Western medicine is diagnosed：Right eye herpes zoster virus keratitis, herpes zoster ophthalmicus post herpetic neuralgia.
Take and wash eye orally with traditional Chinese herbal decoction of the present invention, be within 2 weeks a course for the treatment of.During medication, taboo drinks, marine product and
Hot food.
Two examine：On June 25th, 2007.All diseases have mitigated.Upper prescription after with.Patient is paid a return visit on July 16th, 2007 to fully recover from an illness
More, do not recur again so far.
Case 3（Herpes simplex keratitis cornea）
Slowly certain, female, 63 years old.
The first visit date：On October 6th, 2007.
Main suit：Right eye pain, photophobia, shed tears, foreign body sensation more than 8 months.
Medical history：Patient in 2 months this year panesthesia right eye have foreign matter frictional property pain, the discomfort such as keep in dark place, shed tears, to certain hospital
Ophthalmology has been seen, has given a little medicament for the eyes and anti-inflammatory drugs not to imitate, treatment of transferring from one hospital to another again is examined as viral keratitis, external application dextran
Hydroxypropyl methylcellulose eye drops, shellfish are relaxed medicament for the eyes again, take ACV, vitamin B1, vitamin B12 etc. orally, pain more than the treatment moon
Slightly subtract, but the state of an illness is again and again, drunk aggravation to late September, medication is invalid and to go to a doctor.
Tcm diagnosis：Dendritic keratitis.
Doctor trained in Western medicine is diagnosed：Herpes simplex keratitis.
Take and wash eye orally with traditional Chinese herbal decoction of the present invention, be within 2 weeks a course for the treatment of.During medication, taboo drinks, marine product and
Hot food.
Two examine：On October 15th, 2007.After patient medication 1 week, the state of an illness take a favorable turn, and now feels that the state of an illness mitigates.Continuation is advised to use
Medicine.
Three examine：On October 28th, 2007.3 weeks pain of patient medication disappears, and is recovered not again repeatedly in the follow-up of in September, 2008.
Case 4 (herpes simplex keratitis)
Poplar, man, 59 years old.
The first visit date：On January 8th, 2011.
Main suit：Dry and astringent uncomfortable more than 1 year of left eye.
Medical history：The dry and astringent discomfort of left eye was felt before 1 year, it is sometimes red and swollen, treated through local hospital by keratitis, effect is not good,
When it is light when weight, eyesight declines gradually.After 1 week, left eye is dry and astringent, it is red and swollen aggravate, occur together itch, scorching hot pain, and see the blister of grain of rice size
Rash, is distributed in tufted, after its neighbour sees this, and suspects bleb, but it is rare in eye to fall ill, and dare not assert, it is proposed that true to large hospital
Examine.Go to a doctor in provincial hospital, herpes simplex keratitis is diagnosed as on inspection.After antiviral therapy, ophthalmic uncomfortable is alleviated,
Do not pay attention to again.The antiviral therapies such as conventional ACV are still given, bleb forms a scab quickly, pain disappears, it is again secondary after 1 month to send out
Make, i.e., gone to a doctor again to provincial hospital's ophthalmology, doctor says that this disease is exactly recurrent exerbation, and specific drug is there is no at present.Patient is extremely worried, warp
Online enquiries, carry out undergraduate course and see a doctor then.
Tcm diagnosis：Dendritic keratitis.
Doctor trained in Western medicine is diagnosed：Herpes simplex keratitis.
Take and wash eye orally with traditional Chinese herbal decoction of the present invention, be within 2 weeks a course for the treatment of.During medication, taboo drinks, marine product and
Hot food.
Two examine：On January 22nd, 2011.Patient's readme is after medicine-feeding treatment, and symptom substantially mitigates, and does not occur redness again, therefore
Advise one course for the treatment of of its continual cure, after treatment.On May 30th, 2011 Effect of follow-up visit by telephone, disease recovery from illness, do not recur again.
Six, conclusions
Show that all medicine phases compatibilities of the invention have effects that removing dampness and detoxicating, heat-clearing improving eyesight, removed obstruction in channels to relieve pain by above-mentioned situation,
Autoimmune function can be strengthened with regulation machine vivo environment, serve the effect of good antiviral, anti-inflammatory and analgesic, use
Convenient and simple, short treating period, instant effect, cure rate are high, are to treat having for herpes zoster virus and herpes simplex keratitis
Medicine is imitated, there is significant clinical meaning.
Claims (4)
1. a kind of Chinese medicine for treating herpes zoster and herpes simplex keratitis, it is characterised in that by following weight meter
Material medicine is made：Coptis 8-12g, rheum officinale 5-7g, radix scutellariae 13-17g, chrysanthemum 13-17g, cicada slough 25-35g, windproof 10-14g,
Seed of feather cockscomb 13-17g, Radix Angelicae Sinensis 13-17g, peach kernel 10-14g, safflower 8-12g, scorpio 5-7g, earthworm 10-14g and radix glycyrrhizae 5-7g.
2. the Chinese medicine for the treatment of herpes zoster according to claim 1 and herpes simplex keratitis, it is characterised in that
It is made up of the material medicine of following weight meter：Coptis 9g, rheum officinale 5g, radix scutellariae 14g, chrysanthemum 14g, cicada slough 26g, windproof 11g, feather cockscomb
Sub- 14g, Radix Angelicae Sinensis 14g, peach kernel 11g, safflower 9g, scorpio 5g, earthworm 11g and radix glycyrrhizae 5g.
3. the Chinese medicine for the treatment of herpes zoster according to claim 1 and herpes simplex keratitis, it is characterised in that
It is made up of the material medicine of following weight meter：Coptis 10g, rheum officinale 6g, radix scutellariae 15g, chrysanthemum 15g, cicada slough 30g, windproof 12g, green grass or young crops
Feather cockscomb 15g, Radix Angelicae Sinensis 15g, peach kernel 12g, safflower 10g, scorpio 6g, earthworm 12g and radix glycyrrhizae 6g.
4. the Chinese medicine for the treatment of herpes zoster according to claim 1 and herpes simplex keratitis, it is characterised in that
It is made up of the material medicine of following weight meter：Coptis 11g, rheum officinale 7g, radix scutellariae 16g, chrysanthemum 16g, cicada slough 34g, windproof 13g, green grass or young crops
Feather cockscomb 16g, Radix Angelicae Sinensis 16g, peach kernel 13g, safflower 11g, scorpio 7g, earthworm 13g and radix glycyrrhizae 7g.
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