CN1049027A

CN1049027A - Detergent for skin pollution

Info

Publication number: CN1049027A
Application number: CN 90107427
Authority: CN
Inventors: 付伟
Original assignee: INST OF OCCUPATIONAL MEDICINE CHINA UNIFIED-DISTRIBUTION COAL MINE CORP
Current assignee: INST OF OCCUPATIONAL MEDICINE CHINA UNIFIED-DISTRIBUTION COAL MINE CORP
Priority date: 1990-09-05
Filing date: 1990-09-05
Publication date: 1991-02-06

Abstract

A kind of detergent for skin pollution is the articles for washing of TNT operating personnel special use, it contains kinds of surface promoting agent and S-WAT, eluting rate to skin TNT can reach more than 98%, strong detergency has stronger foaming and soaks into low temperature resistant resistance to hard water, this product is neutral liquid, have characteristics such as nontoxic, non-stimulated, safe and reliable, easy to use, can prevent effectively that TNT from absorbing through skin, can reduce the generation of occupational poisoning.

Description

Detergent for skin pollution

Detergent for skin pollution is the articles for washing of TNT operating personnel special use.

Trotyl (TNT) is the major ingredient of pin ammonpulver, it is widely used in defense and commercial industry, in recent years because the reinforcement of technological innovation and dust prevention, the airborne TNT concentration of production plant reaches substantially or is lower than China maximum allowable concentration (1mg/m ³), but direct labor's TNT chronic poisoning or TNT cataract incidence do not have obvious decline, and most workmans are based on manual operations, skin contamination is very serious, it was reported that certain workman of factory whole skin average T NT contamination level can reach 2.2 6g, wherein be mainly hand skin and pollute.The Recent study report thinks that the TNT skin absorption is to cause TNT chronic poisoning and the cataractous major cause of TNT, the TNT that pollutes skin surface and other component (pitch prill, paraffin wax, ammonium nitrate) of explosive and sebum, sweat, machine greasy dirt mix the TNT dirt that formation is insoluble in water and are adsorbed in skin surface, all can not remove the TNT of skin contamination effectively with common soap or S-WAT.

The major ingredient of soap is a sodium stearate, and foam is few during use, and wettability is poor, and resistance to hard water is low, and China TNT explosive factory majority is built the mountain area in, and water quality is harder, and its detersive power is reduced, and soap can not be removed the TNT of skin contamination at all effectively.

Though the cleaning performance of S-WAT is better than soap, but its can only with the dinitrobenzene sulfonic acid sodium of TNT water generation reaction dissolubility, the no soil-removing action of S-WAT itself, clean effect to the TNT mixed dirt that contains ammonium nitrate, greasy dirt, sebum, sweat is not good, and alkalescence is strong, big to skin irritation, part factory has now stopped using S-WAT.

Therefore, take effective skin protection measure, the TNT of in time and effectively peace and quiet workman's skin contamination is the key of current prevention TNT chronic poisoning.

Purpose of the present invention just is to provide a kind of skin clean-out system of TNT special use, can remove skin TNT quickly and efficiently and pollute, and prevents that TNT from absorbing through skin, reduces the generation of occupational poisoning, and protection TNT operating personnel's is healthy.

The present invention contains the kinds of surface promoting agent: sodium lauryl sulphate, lauryl alcohol diglycollic amide, trolamine and S-WAT, transfer pH value with citric acid solution, and mix micro-spices, contained composition is preparation by weight percentage all, surplus is a distilled water, and its prescription is as follows:

The composition weight percent

A, sodium lauryl sulphate 10～15

B, lauryl alcohol diglycollic amide 4～6

C, trolamine 4

D, S-WAT 3～5

E, spices 0.4～0.6

F, citric acid an amount of (transferring PH is 6.5)

Distilled water is made into 100

Compound method is: sodium lauryl sulphate is made into 50% solution with dissolved in distilled water, getting lauryl alcohol diglycollic amide and trolamine by weight percentage joins in 50% sodium dodecyl sulfate solution, heat temperature raising to 65 ℃, and stir, 25% sodium sulfite solution that will prepare by weight percentage then joins in the mixed solution, and stirring and evenly mixing, incubation is 15～20 minutes under 65 ℃ of conditions, controlled temperature must not be above 70 ℃, pH value with 50% citric acid regulating solution is 6.5 at last, and add 0.4～0.6% spices stirring and evenly mixing, be cooled at ambient temperature 30 ℃ the bottling all sorts of flowers odor type, pale brown look, transparent viscous liquid is the special-purpose skin clean-out system of TNT operating personnel ideal.

The present invention compares with existing articles for washing has following advantage:

1, tensio-active agent is the major ingredient of washing composition in modern age, and sodium lauryl sulphate wherein contains hydrophobic and hydrophilic two kinds of chemical groups, and fat-soluble and water-soluble dirt is all had stronger detersive power, and has stronger foaming infiltration, low temperature resistant resistance to hard water; It is neutral that the lauryl alcohol diglycollic amide is, and skin is had the certain protection effect; Trolamine is a solubilizing agent; During cleaning, tensio-active agent can soak into the skin surface of TNT mixed dirt rapidly, forms separating interface, by foam, emulsification, mechanical friction effect, makes TNT break away from skin surface, is suitable for mountain area TNT factory and uses.

2, S-WAT has certain wash-out TNT effect, utilizes itself and TNT reaction to generate red dinitrobenzene sulfonic acid sodium as indicator simultaneously, and whether the TNT of workman's energy self check skin contamination is cleaned up.

3, this product pH value is 6.5 to be neutral, and detected result is indicated as nontoxic, non-stimulated, safe and reliable TNT personal cleansing articles for use.

4, this product is easy to use, and wash one's hands, wash hair, have a bath and can once finish, eluting rate height, but water saving and shortening washing time, it is constant to overcome the use of soap and S-WAT, the shortcoming that alkalescence is strong.

Because the comprehensive action of multiple components can produce stronger clean effect, the eluting rate to skin TNT in the time of 20 ℃ can reach more than 98%, can reach 99.1% in the time of 40 ℃, and prevention TNT chronic poisoning is had realistic meaning with the labour protection that improves the workman.

The invention will be further described below in conjunction with embodiment:

The test of washing one's hands of example 1, laboratory simulation scene

(1) different purging method, the cleaning performance that skin TNT is polluted:

When the TNT contamination level is 1.0mg, 1 hour pollution time, during 20 ℃ of water temperatures, use this product respectively, 5% S-WAT and tap water clean, its eluting rate such as following table:

Purging method this product 5% S-WAT tap water
	TNT residual quantity (μ g) 15.1 ± 7.80 151.3 ± 4.82 263.6 ± 6.71
Eluting rate (%) 98.5 84.9 73.6

The eluting rate height of this product as seen from the above table, strong detergency.

(2) this product is to the cleaning performance of different TNT contamination leveies:

Skin pollution quantity is divided into 25 μ g/cm ², 50 μ g/cm ², 100 μ g/cm ²Three groups, 1 hour pollution time, 20 ℃ of water temperatures, it is as follows to clean the skin result with this product 0.2ml:

TNT contamination level (μ g/cm ²) 25 50 100
	TNT residual quantity (μ g) 8.01 ± 5.5 15.1 ± 7.8 39.3 ± 8.7
Eluting rate (%) 98.4 98.5 98

How much obviously the eluting rate of this product can not remain on more than 98% substantially because of the degree of changing of contamination level as seen from the above table.

The above results shows the eluting rate height of this product, therefore can prevent effectively that TNT from absorbing through skin, can reduce the generation of occupational poisoning.

Example 2, toxicology, hygiology index determining

(1) skin irritation test:

Animal be purebredly exempt from vain, male, healthy, body weight 3kg, 6 of quantity are undertaken by the method for " Hygiene Toxicology ultimate principle and method " book defined, calculating direct stimulation index according to 1,8,24,48,72 hour observations is zero.

(2) eye mucosa irritant test:

To be that New Zealand is purebred exempt from animal in vain, male, healthy, more than the body weight 3kg, and 6 of quantity are undertaken by the method for " Hygiene Toxicology ultimate principle and method " book defined, observe 1,24,48,72 hour, all do not have irritant reaction.

(3) acute and chronic toxicity test:

Its major ingredient is a sodium lauryl sulphate, and rat oral clothes LD50 is 2.64kg/kg, and its mouse oral clothes LD50 is 2.7g/kg, and feeds and raise 1000ppm/ day, obeys equal non-toxic reaction after 90 days altogether.

(4) the hygiology index detects:

Chemical index: mercury＜0.025mg/kg, arsenic＜1.0mg/kg,

Lead＜5.0mg/kg

Microbiological indicator:

Total plate count＜10/milliliter (gram), excrement colibacillus group: feminine gender, Pseudomonas aeruginosa: do not detect streptococcus aureus: do not detect.

In sum, it is nontoxic to detect proof this product through hygiology, toxicologic index, and mucocutaneous and eye mucosa are not had any hormesis, is a kind of safe and reliable articles for washing.

Example 3, physicochemical property detect:

This product neutrality, pH value 6.5 is transparent viscous liquid, under-10 ℃ and 48 ℃ of conditions, keeps respectively 24 hours, when waiting to return to 25 ℃ of room temperatures, does not all have the oily water separation phenomenon.

When this product centrifugal speed is 4000v/min, during centrifugation time 30min, demixing phenomenon does not appear, and foam is abundant, fine and smooth, and lathering property is good, and physical and chemical index has reached the top grade product level of national articles for washing.

Claims

1, a kind of detergent for skin pollution that contains S-WAT is characterized in that containing sodium lauryl sulphate, lauryl alcohol diglycollic amide and trolamine.

2, by the described detergent for skin pollution of claim 1, it is characterized in that all preparations by weight percentage of contained composition, it is as follows to fill a prescription:

Composition weight percent %

A, sodium lauryl sulphate 10～15

B, lauryl alcohol diglycollic amide 4～6

C, trolamine 4

D, S-WAT 3～5

E, citric acid an amount of (transferring pH value is 6.5)

F, spices 0.4～0.6

Distilled water is made into 100

3, by the described detergent for skin pollution of claim 1, it is characterized in that compound method is: sodium lauryl sulphate is made into 50% solution with dissolved in distilled water, getting lauryl alcohol diglycollic amide and trolamine by weight percentage joins in 50% sodium dodecyl sulfate solution, heat temperature raising to 65 ℃, and stir, 25% sodium sulfite solution that will prepare by weight percentage then joins in the mixed solution, and stirring and evenly mixing, incubation is 15～20 minutes under 65 ℃ of conditions, the control temperature rise is no more than 70 ℃, pH value with 50% citric acid regulating solution is 6.5 at last, and add 0.4～0.6% spices and stir, be cooled to 30 ℃ of bottlings at ambient temperature.

4,, it is characterized in that it being the scavenger specially of the trotyl (TNT) that is used for removing skin contamination by the described detergent for skin pollution of claim 1.