CN104887864A - Preparation for treating gout and preparation method therefor - Google Patents
Preparation for treating gout and preparation method therefor Download PDFInfo
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- CN104887864A CN104887864A CN201510380983.0A CN201510380983A CN104887864A CN 104887864 A CN104887864 A CN 104887864A CN 201510380983 A CN201510380983 A CN 201510380983A CN 104887864 A CN104887864 A CN 104887864A
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Abstract
The invention discloses a preparation for treating gout. The preparation is mainly prepared from the following raw pharmaceutical materials in parts by mass: 12-18 parts of magnolia bark, 8-16 parts of rubus hirsutus, 11-15 parts of honeysuckle stem, 9-16 parts of celastrus aculeatus, 7-14 parts of semen strychni, 11-16 parts of poria cocos, 9-16 parts of clematis, 13-18 parts of curculigo capitulata, 7-15 parts of grifola umbellata, 11-16 parts of erythrina bark, 9-13 parts of nude fern herb, 12-16 parts of daphne odora leaves, 10-13 parts of herba siegesbeckiae, 6-10 parts of fox meat and 8-15 parts of damnacanthus. The preparation has the advantages of good treatment effect, high cure rate, short treatment course, recurrence prevention and the like; the preparation is a pure traditional Chinese medicine preparation, the pharmaceutical materials are cheap and are easily obtained, and the preparation is free of any toxic or side effect and is safe to take; the preparation completely accords with the principle of traditional Chinese medicine, has the effects of removing dampness and promoting diuresis, dredging collaterals and relieving pain, and the like and can be used for treating gout in both symptoms and root causes.
Description
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to a kind of preparation for the treatment of gout and preparation method thereof.
Background technology
Gout a kind of to increase due to biosynthesis of purine metabolism, uric acid produce too much or because urate excretion is bad in hyperamization uric acid raise, urate crystal is deposited on synovium of joint, synovial bursa, the repeated relapsing inflammatory diseases caused in cartilage and hetero-organization thereof.Characteristic acute and chronic arthritis, tophus, the interstitial nephritis of its Clinical symptoms caused by: hyperuricemia and urate crystal deposition, severe patient is shown in joint deformity and dysfunction, the uric acid lithangiuria of normal companion, is more common in middle-aging male and the postmenopausal women of bodily form obesity.By etiological classification, constitutional and the large class of Secondary cases two can be divided into.Primary gout has certain Familial Occurrence, and the patient of about 20% has Positive family history.Except primary gout except about 1% is caused by congenital enzyme defects, most pathogenic factor is failed to understand.Secondary gout betides in other diseases process, as nephropathy, hematopathy, or causes owing to taking the many reasons such as some drugs, tumor chemoradiotherapy.Acute stage, intermission, chronic phase can be divided into according to the natural history of gout.Arthralgia acute attack is the classical symptom of acute gout.Seizure of disease is many after slight damage, hyperalimentation or relevant disease, is apt to occur in far-end of limb joint especially, and typical symptom is sent out in toes (podagra), also can cause renal colic because of urate calculi.The asymptomatic intermission is the relieved state repeatedly between acute attack, after gout acute attack is alleviated, generally without obvious sequela shape, sometimes only has outbreak area skin pigment to deepen, and in kermesinus or aubergine, desquamation, to itch, or has slight joint symptoms.Chronic gout is changed to feature with destructive joint.
Publication No. CN 104189662 A(application number 201410423046.4) Chinese patent literature disclose a kind of Tibetan medicine for the treatment of gout, medicine material consist of Radix Stephaniae Sinicae (Radix Stephaniae Dielsianae) 8-12 gram, Radix Rumicis Crispi 8-12 gram, Rhizoma Smilacis Glabrae 5-7 gram, Cortex Eucommiae 4-6 gram, Colchicum autumnale 2-4 gram, Herba Plantaginis 4-6 gram, Flos Carthami 4-6 gram, Cacumen Platycladi 2-4 gram, Ganoderma 3-5 gram.Publication No. CN 103623301 A(application number 201310610239.6) Chinese patent literature disclose the Chinese medicine for the treatment of gout, it is made for raw material with Semen Cassiae, Semen Raphani, Rhizoma Smilacis Glabrae, Flos Lonicerae, Fructus Lycii, Radix Glycyrrhizae, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong, Caulis Lonicerae, Rhizoma Polygoni Cuspidati, the Radix Paeoniae Alba, Cortex Phellodendri, Caulis Lonicerae.Publication No. CN 104352901 A(application number 201410526496.6) Chinese patent literature disclose a kind of Chinese medicine for the treatment of gout, component has the Radix Astragali, the Radix Paeoniae Alba, Semen Coicis, Semen Plantaginis, Rhizoma Et Radix Notopterygii, Rhizoma Arisaematis (processed) ， Rhizoma Dioscoreae Septemlobae, Radix Angelicae Sinensis, Rhizoma Smilacis Glabrae, Radix Saposhnikoviae, Radix Clematidis, Cortex Cinnamomi, Nidus Vespae, Herba Lysimachiae.
The sickness rate cumulative year after year of gout, though western medicine gout instant effect, but side effect is large, and easily damage the internal organs of patient, treatment by Chinese herbs is comparatively safe, but some Chinese medicine formulas are responded well to treatment slowly, the course for the treatment of is long, and therapeutic effect is not ideal enough, therefore, need to develop a kind of instant effect, eutherapeutic traditional Chinese medical science formula.
Summary of the invention
For the deficiencies in the prior art, the object of this invention is to provide a kind of preparation for the treatment of gout of safe and effective, taking convenience and preparation method thereof.
Technical scheme of the present invention is:
Treat a preparation for gout, be prepared from primarily of following bulk drugs, be mass parts: Cortex Magnoliae Officinalis 12-18, pallet 8-16, Caulis Lonicerae 11-15, Celastrus aceleatus Merr 9-16, Semen Strychni 7-14, Poria 11-16, Radix clematidis floridae 9-16, great Ye Rhizoma Curculiginis 13-18, Polyporus 7-15, Cortex erythrinae 11-16, Herba Psiloti Nudi 9-13, Folium daphnes odorae 12-16 ， Herba Siegesbeckiae 10-13, Carnis Vulpes 6-10, Herba Damnacanthi 8-15.
In preferred scheme, Cortex Magnoliae Officinalis 14-16, pallet 10-14, Caulis Lonicerae 12-14, Celastrus aceleatus Merr 10-15, Semen Strychni 9-12, Poria 12-14, Radix clematidis floridae 11-14, great Ye Rhizoma Curculiginis 14-17, Polyporus 9-13, Cortex erythrinae 12-15, Herba Psiloti Nudi 10-12, Folium daphnes odorae 13-15 Herba Siegesbeckiae 11-12, Carnis Vulpes 7-9, Herba Damnacanthi 10-13.
Be more preferably, Cortex Magnoliae Officinalis 15, pallet 12, Caulis Lonicerae 13, Celastrus aceleatus Merr 12.5, Semen Strychni 10.5, Poria 13.5, Radix clematidis floridae 12.5, great Ye Rhizoma Curculiginis 15.5, Polyporus 11, Cortex erythrinae 13.5, Herba Psiloti Nudi 11, Folium daphnes odorae 14, Herba Siegesbeckiae 11.5, Carnis Vulpes 8, Herba Damnacanthi 11.5.
Described a kind of preparation for the treatment of gout, be made into pharmaceutically acceptable decoction, its preparation method is:
(1) get pallet decontamination, clean, infiltrate with clear water, section, yellow wine and hydromel mixing are made mixed liquor, and pallet sheet dips in mixed liquor and is placed on fire and dries, and repetitive operation three times, after drying for the last time, dries in the air cool;
(2) by Celastrus aceleatus Merr, great Ye Rhizoma Curculiginis and Cortex erythrinae decontamination, clean, boil with yellow wine, after wine exhausts, take out, wrap up three layers, be placed in hot ash with wet toilet paper, when simmering dried-up to outer paper, take out, removing paper, dries;
(3) get Radix clematidis floridae, Herba Psiloti Nudi, Folium daphnes odorae He Herba Siegesbeckiae decontamination, clean, mix thoroughly with Sucus Zingberis, infiltrate 20 minutes, take out, put into pot Steam by water bath 15 minutes, take out, dry;
(4) Carnis Vulpes is cleaned, mix thoroughly with vinegar and Rhizoma Zingiberis, moistening 10 minutes, Carnis Vulpes and Rhizoma Zingiberis are poured in boiling water and scalds 10 minutes, pull out, dry in the air cool, diced, decoct with water together with the Cortex Magnoliae Officinalis cleaned, Caulis Lonicerae, Semen Strychni, Poria, Polyporus, Herba Damnacanthi and step (1) (2) (3) made crude drug, big fire is boiled rear little fire and is decocted 30-42 minute (preferred, 34-38 minute decocted by little fire; Be more preferably, little fire decocts 36 minutes), filter, collect medicinal liquid, obtain decoction.
Described a kind of preparation method for the treatment of the preparation decoction of gout, step (4) amount of water is that doubly (preferred, amount of water is 7.5-8.5 times of total raw material medicine quality to the 7-9 of total raw material medicine quality; Be more preferably, amount of water is 8 times of total raw material medicine quality).
Described a kind of preparation for the treatment of gout, be made into pharmaceutically acceptable capsule, its preparation method is:
(1) get pallet decontamination, clean, infiltrate with clear water, section, yellow wine and hydromel mixing are made mixed liquor, and pallet sheet dips in mixed liquor and is placed on fire and dries, and repetitive operation three times, after drying for the last time, dries in the air cool;
(2) by Celastrus aceleatus Merr, great Ye Rhizoma Curculiginis and Cortex erythrinae decontamination, clean, boil with yellow wine, after wine exhausts, take out, wrap up three layers, be placed in hot ash with wet toilet paper, when simmering dried-up to outer paper, take out, removing paper, dries;
(3) get Radix clematidis floridae, Herba Psiloti Nudi, Folium daphnes odorae He Herba Siegesbeckiae decontamination, clean, mix thoroughly with Sucus Zingberis, infiltrate 20 minutes, take out, put into pot Steam by water bath 15 minutes, take out, dry;
(4) Carnis Vulpes is cleaned, mix thoroughly with vinegar and Rhizoma Zingiberis, moistening 10 minutes, Carnis Vulpes and Rhizoma Zingiberis are poured into boiling water to scald 10 minutes, pull out, dry in the air cool, diced, decoct with water (amount of water is 8 times of total raw material medicine quality) together with the Cortex Magnoliae Officinalis cleaned, Caulis Lonicerae, Semen Strychni, Poria, Polyporus, Herba Damnacanthi and step (1) (2) (3) made crude drug, big fire is boiled rear little fire and is decocted, and decocts three times altogether, merges three gained medicinal liquids, concentrating under reduced pressure, dry, pulverize, make medicated powder, incapsulate, obtain capsule.
Described a kind of preparation method for the treatment of the preparation capsule of gout, step (4) big fire is boiled rear little fire and is decocted 30-42 minute (preferred, 34-38 minute decocted by little fire; Be more preferably, little fire decocts 36 minutes).
Described a kind of preparation for the treatment of gout, be made into pharmaceutically acceptable tablet, its preparation method is:
(1) get pallet decontamination, clean, infiltrate with clear water, section, yellow wine and hydromel mixing are made mixed liquor, and pallet sheet dips in mixed liquor and is placed on fire and dries, and repetitive operation three times, after drying for the last time, dries in the air cool;
(2) by Celastrus aceleatus Merr, great Ye Rhizoma Curculiginis and Cortex erythrinae decontamination, clean, boil with yellow wine, after wine exhausts, take out, wrap up three layers, be placed in hot ash with wet toilet paper, when simmering dried-up to outer paper, take out, removing paper, dries;
(3) get Radix clematidis floridae, Herba Psiloti Nudi, Folium daphnes odorae He Herba Siegesbeckiae decontamination, clean, mix thoroughly with Sucus Zingberis, infiltrate 20 minutes, take out, put into pot Steam by water bath 15 minutes, take out, dry;
(4) Carnis Vulpes is cleaned, mix thoroughly with vinegar and Rhizoma Zingiberis, moistening 10 minutes, Carnis Vulpes and Rhizoma Zingiberis are poured into boiling water to scald 10 minutes, pull out, dry in the air cool, diced, decoct with water together with Herba Damnacanthi (amount of water is 8 times of boiled crude drug quality) with the Cortex Magnoliae Officinalis cleaned, Caulis Lonicerae, Semen Strychni, Poria, Polyporus, big fire is boiled rear little fire and is decocted 30-42 minute (preferred, 34-38 minute decocted by little fire; Be more preferably, little fire decocts 36 minutes), decoct three times altogether, merge three gained medicinal liquids, concentrating under reduced pressure, dry, pulverize, and makes medicated powder;
(5) pulverized and sieved by step (1) (2) (3) made crude drug, mix with step (4) made medicated powder, obtained mixed powder, by made mixed powder, is processed into tablet dosage form according to the preparation for processing of tablet, obtains tablet.
Described a kind of preparation method for the treatment of the formulation tablet of gout, step (5) was pulverized 120-160 mesh sieve and (preferably, was pulverized 130-150 mesh sieve; Be more preferably, pulverized 140 mesh sieves).
Described a kind of preparation for the treatment of gout, be made into pharmaceutically acceptable pill, its preparation method is:
(1) get pallet decontamination, clean, infiltrate with clear water, section, yellow wine and hydromel mixing are made mixed liquor, and pallet sheet dips in mixed liquor and is placed on fire and dries, and repetitive operation three times, after drying for the last time, dries in the air cool;
(2) by Celastrus aceleatus Merr, great Ye Rhizoma Curculiginis and Cortex erythrinae decontamination, clean, boil with yellow wine, after wine exhausts, take out, wrap up three layers, be placed in hot ash with wet toilet paper, when simmering dried-up to outer paper, take out, removing paper, dries;
(3) get Radix clematidis floridae, Herba Psiloti Nudi, Folium daphnes odorae He Herba Siegesbeckiae decontamination, clean, mix thoroughly with Sucus Zingberis, infiltrate 20 minutes, take out, put into pot Steam by water bath 15 minutes, take out, dry;
(4) Carnis Vulpes is cleaned, mix thoroughly with vinegar and Rhizoma Zingiberis, moistening 10 minutes, Carnis Vulpes and Rhizoma Zingiberis are poured into boiling water to scald 10 minutes, pull out, dry in the air cool, diced, decoct with water together with Herba Damnacanthi (amount of water is 8 times of boiled crude drug quality) with the Cortex Magnoliae Officinalis cleaned, Caulis Lonicerae, Semen Strychni, Poria, Polyporus, big fire is boiled rear little fire and is decocted 30-42 minute (preferred, 34-38 minute decocted by little fire; Be more preferably, little fire decocts 36 minutes), decoct three times altogether, merge three gained medicinal liquids, concentrating under reduced pressure, dry, pulverize, and makes medicated powder;
(5) pulverized and sieved by step (1) (2) (3) made crude drug, mix with step (4) made medicated powder, obtained mixed powder, adds refined honey and water, and ball block, ball bar, and gradation, round are dry, obtain pill.
Described a kind of preparation method for the treatment of the preparation pill of gout, step (5) was pulverized 80-120 mesh sieve and (preferably, was pulverized 90-110 mesh sieve; Be more preferably, pulverized 100 mesh sieves).
A kind of preparation recipe science for the treatment of gout provided by the invention, medication is simple, makes simple and easy.In addition, excellent results of the present invention also shows:
1, the present invention has good effect, and cure rate is high, short treating period, the advantages such as anti-recurrence;
2, the present invention is pure Chinese medicinal preparation, and medical material is cheap and easy to get, without any side effects, takes safety;
3, this prescription meets Chinese medicine principle completely, has the effect such as promoting diuresis to eliminate damp pathogen, removing obstruction in the collateral to relieve pain, can treating both the principal and secondary aspects of a disease gout.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Cortex Magnoliae Officinalis: base is former: be bark or the root bark of Magnoliacea plant Cortex Magnoliae Officinalis or magnolia officinalis rehd.et wils.var.biloba rehd.et wils..Nature and flavor: bitter, pungent, temperature.Gui Jing: return spleen, stomach, lung, large intestine channel.Function cures mainly: dampness expectorant, and the therapeutic method to keep the adverse QI flowing downwards is except full.For humidity hysteresis damaging the spleen and stomach, gastral cavity painful abdominal mass is vomited and diarrhoea, and stagnation of QI due to dyspepsia, abdominal distention constipation, phlegm retention is breathed with cough.
Pallet: base is former: be the root of Rosaceae rubus pallet.Nature and flavor: sour, micro-hardship are flat.Function cures mainly: heat-clearing and toxic substances removing, reducing swelling and alleviating pain, hemostasis.Cure mainly influenza, children with high fever induced convulsions, laryngopharynx swelling and pain, toothache, headache, bones and muscles pain due to rheumatism, furuncle and phyma.
Caulis Lonicerae: base is former: be the stem and leaf of caprifoliaceae plant Radix Ophiopogonis.Nature and flavor: sweet, cold.Gui Jing: enter the heart, lung meridian.Function cures mainly: heat clearing away, removing toxic substances, dredging collateral.Control epidemic febrile disease heating, toxic-heat and blood stasis, infectious hepatitis, carbuncle sore tumefacting virus, bones and muscles pain.
Celastrus aceleatus Merr: base is former: be the root of Celastraceae plant Celastrus aceleatus Merr.Nature and flavor: bitter, pungent, cool.Gui Jing: liver, gallbladder, kidney channel.Function cures mainly: heat-clearing and toxic substances removing, expelling wind and removing dampness.Main air pain of dampness syndrome, gout, nephritis, cholecystitis, leukemia.
Semen Strychni: base is former: be the mature seed of loganiaceae plant Semen Strychni.Nature and flavor: bitter, temperature; Very toxic.Gui Jing: return liver, spleen channel.Function cures mainly: removing obstruction in the collateral to relieve pain, mass dissipating and swelling eliminating.For rheumatoid arthritis stubborn, paralysis and numbness, injury from falling down, ulcer sore pain; Poliomyelitis sequela, rheumatoid arthritis.
Poria: base is former: be the sclerotium of On Polyporaceae Poria.Nature and flavor: sweet, light are flat.Gui Jing: GUIXIN, lung, spleen, kidney channel.Function cures mainly: promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming.For edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, palpitation with fear insomnia.
Radix clematidis floridae: base is former: be root or the herb of cohosh Radix clematidis floridae.Nature and flavor: bitter in the mouth, micro-pungent, warm in nature, mild toxicity.Gui Jing: return liver, spleen, kidney channel.Function cures mainly: diuresis, dredging collateral, regulating the flow of QI to relieve constipation, removing toxic substances.Cure mainly rheumatic arthritis, dysuria, amenorrhea, constipation abdominal distention, acute toothache, eye plays punctate keratitis, worm venom, jaundice.
Great Ye Rhizoma Curculiginis: base is former: the root of Hypoxidaceae Curculigo great Ye Rhizoma Curculiginis and root stock.Nature and flavor: bitter, puckery are flat.Function cures mainly: moistening the lung and resolving phlegm, relieving cough and asthma, calm spleen invigorating, tonifying the kidney to consolidate the essence.For dyspnea and cough due to deficiency of the kidney, soreness of waist and knee joint, leucorrhea, seminal emission.
Polyporus: base is former: be the dry sclerotia of Polyporaceae plant Polyporus.Nature and flavor: sweet, light are flat.Gui Jing: return kidney, urinary bladder channel.Function cures mainly: promoting diuresis to eliminate damp pathogen.For dysuria, edema, has loose bowels, stranguria with turbid discharge, leukorrhagia.
Cortex erythrinae: base is former: be the dried bark of leguminous plant erythrina indica.Nature and flavor: bitter are flat.Gui Jing: return liver, kidney channel.Function cures mainly: wind-damp dispelling, channels sootheing and network vessel quickening.For rheumatic numbness, waist hamstring bone pain, traumatic injury, various stubborn dermatitis is controlled in external.
Herba Psiloti Nudi: base is former: be the herb of Psilotaceae plant Psilotum nudum.Nature and flavor: sweet, acrid, warm.Gui Jing: enter the heart, liver, stomach warp.Function cures mainly: promoting blood circulation to restore menstrual flow, wind-damp dispelling.Dispelling the wind and dampness pathogens arthralgia pain, women's amenorrhea, spits blood and traumatic injury.
Folium daphnes odorae: base is former: be the blade of Isolated From Thymelaeaceae Species winter daphne.Nature and flavor: acrid in the mouth, property is put down.Gui Jing: lung, spleen channel.Function cures mainly: removing toxic substances, reducing swelling and alleviating pain.Main skin infection, acute mastitis, gout.
Herba Siegesbeckiae: base is former: be the aerial parts of feverfew Herba Siegesbeckiae.Nature and flavor: pungent, bitter, cold.Gui Jing: return liver, kidney channel.Function cures mainly: wind-damp dispelling, sharp joint, removing toxic substances.For rheumatic arthralgia, muscles and bones is unable, soreness of the waist and knees, quadriplegia, hemiplegia, rubella eczema.
Carnis Vulpes: base is former: be the meat of Canis animals Vulpes.Nature and flavor: sweet, temperature.Function cures mainly: during tonify deficiency is warm, separate sore.Control asthenia, forgetful, infantile convulsion, aqueous vapor general edema with yellowish skin, scabies.
Herba Damnacanthi: base is former: be herb or the root of Maguireothamnus speciosus Herba Damnacanthi.Nature and flavor: bitter sweet are flat.Function cures mainly: expelling wind and removing dampness, promoting blood circulation and detumescence.Control gout, rheumatic arthralgia.Cough due to fluid-retention, lung abscess, edema, mass in the abdomen, jaundice, women's amenorrhea, infantile malnutrition, urticaria, traumatic injury.
embodiment 1treat a preparation for gout, be prepared from (every part of 10g) primarily of following bulk drugs: Cortex Magnoliae Officinalis 12 parts, 8 parts, pallet, Caulis Lonicerae 11 parts, Celastrus aceleatus Merr 9 parts, Semen Strychni 7 parts, 11 parts, Poria, Radix clematidis floridae 9 parts, great Ye Rhizoma Curculiginis 13 parts, Polyporus 7 parts, Cortex erythrinae 11 parts, Herba Psiloti Nudi 9 parts, Folium daphnes odorae 12 parts of Herba Siegesbeckiaes 10 parts, Carnis Vulpes 6 parts, Herba Damnacanthi 8 parts.
Above-mentioned a kind of preparation method for the treatment of the preparation decoction of gout is:
(1) get pallet decontamination, clean, infiltrate with clear water, section, yellow wine and hydromel mixing are made mixed liquor, and pallet sheet dips in mixed liquor and is placed on fire and dries, and repetitive operation three times, after drying for the last time, dries in the air cool;
(2) by Celastrus aceleatus Merr, great Ye Rhizoma Curculiginis and Cortex erythrinae decontamination, clean, boil with yellow wine, after wine exhausts, take out, wrap up three layers, be placed in hot ash with wet toilet paper, when simmering dried-up to outer paper, take out, removing paper, dries;
(3) get Radix clematidis floridae, Herba Psiloti Nudi, Folium daphnes odorae He Herba Siegesbeckiae decontamination, clean, mix thoroughly with Sucus Zingberis, infiltrate 20 minutes, take out, put into pot Steam by water bath 15 minutes, take out, dry;
(4) Carnis Vulpes is cleaned, mix thoroughly with vinegar and Rhizoma Zingiberis, moistening 10 minutes, Carnis Vulpes and Rhizoma Zingiberis are poured in boiling water and scalds 10 minutes, pull out, dry in the air cool, diced, decoct with water (amount of water is 8 times of total raw material medicine quality) together with the Cortex Magnoliae Officinalis cleaned, Caulis Lonicerae, Semen Strychni, Poria, Polyporus, Herba Damnacanthi and step (1) (2) (3) made crude drug, big fire is boiled rear little fire and is decocted 36 minutes, filter, collect medicinal liquid, obtain decoction.
embodiment 2treat a preparation for gout, be prepared from (every part of 10g) primarily of following bulk drugs: Cortex Magnoliae Officinalis 18 parts, 16 parts, pallet, Caulis Lonicerae 15 parts, Celastrus aceleatus Merr 16 parts, Semen Strychni 14 parts, 16 parts, Poria, Radix clematidis floridae 16 parts, great Ye Rhizoma Curculiginis 18 parts, Polyporus 15 parts, Cortex erythrinae 16 parts, Herba Psiloti Nudi 13 parts, Folium daphnes odorae 16 parts of Herba Siegesbeckiaes 13 parts, Carnis Vulpes 10 parts, Herba Damnacanthi 15 parts.
A kind of preparation method for the treatment of the preparation capsule of gout is:
(1) get pallet decontamination, clean, infiltrate with clear water, section, yellow wine and hydromel mixing are made mixed liquor, and pallet sheet dips in mixed liquor and is placed on fire and dries, and repetitive operation three times, after drying for the last time, dries in the air cool;
(2) by Celastrus aceleatus Merr, great Ye Rhizoma Curculiginis and Cortex erythrinae decontamination, clean, boil with yellow wine, after wine exhausts, take out, wrap up three layers, be placed in hot ash with wet toilet paper, when simmering dried-up to outer paper, take out, removing paper, dries;
(3) get Radix clematidis floridae, Herba Psiloti Nudi, Folium daphnes odorae He Herba Siegesbeckiae decontamination, clean, mix thoroughly with Sucus Zingberis, infiltrate 20 minutes, take out, put into pot Steam by water bath 15 minutes, take out, dry;
(4) Carnis Vulpes is cleaned, mix thoroughly with vinegar and Rhizoma Zingiberis, moistening 10 minutes, Carnis Vulpes and Rhizoma Zingiberis are poured into boiling water to scald 10 minutes, pull out, dry in the air cool, diced, decoct with water (amount of water is 8 times of total raw material medicine quality) together with the Cortex Magnoliae Officinalis cleaned, Caulis Lonicerae, Semen Strychni, Poria, Polyporus, Herba Damnacanthi and step (1) (2) (3) made crude drug, big fire is boiled rear little fire and is decocted 36 minutes, decocts three times altogether, merges three gained medicinal liquids, concentrating under reduced pressure, dry, pulverize, make medicated powder, incapsulate, obtain capsule.
Model case: xxx, female, 46 years old.Main suit: prominent sense left foot metatarsophalangeal joints pain two months ago, local skin is red and swollen, scorching hot, exacerbation of symptoms in a couple of days, difficulty in walking, joint motion is limited, dizziness and tinnitus, the colour of skin is purple dark, tenderness, examination in hospital, red tongue, yellow and greasy fur, deep and stringy pulse, blood uric acid 524.5 μm of ol/L, erythrocyte sedimentation rate 25 mm/h, is diagnosed as gout.
Take a kind of preparation capsule for the treatment of gout of the present embodiment gained, every day 2 times, each 3, warm water delivery service, 15 days courses for the treatment of.After taking 3 days, toe joint pain, redness obviously disappear, and after taking a course for the treatment of, without malaise symptoms, freely, check, blood uric acid 284.3 μm of ol/L, patient fully recovers, and consolidates and takes drug withdrawal after a course for the treatment of, follow up a case by regular visits to and do not recur in 1 year in toe joint activity.
embodiment 3treat a preparation for gout, be prepared from (every part of 10g) primarily of following bulk drugs: Cortex Magnoliae Officinalis 14 parts, 10 parts, pallet, Caulis Lonicerae 12 parts, Celastrus aceleatus Merr 10 parts, Semen Strychni 9 parts, 12 parts, Poria, Radix clematidis floridae 11 parts, great Ye Rhizoma Curculiginis 14 parts, Polyporus 9 parts, Cortex erythrinae 12 parts, Herba Psiloti Nudi 10 parts, Folium daphnes odorae 13 parts of Herba Siegesbeckiaes 11 parts, Carnis Vulpes 7 parts, Herba Damnacanthi 10 parts.
A kind of preparation method for the treatment of the formulation tablet of gout is:
(1) get pallet decontamination, clean, infiltrate with clear water, section, yellow wine and hydromel mixing are made mixed liquor, and pallet sheet dips in mixed liquor and is placed on fire and dries, and repetitive operation three times, after drying for the last time, dries in the air cool;
(2) by Celastrus aceleatus Merr, great Ye Rhizoma Curculiginis and Cortex erythrinae decontamination, clean, boil with yellow wine, after wine exhausts, take out, wrap up three layers, be placed in hot ash with wet toilet paper, when simmering dried-up to outer paper, take out, removing paper, dries;
(3) get Radix clematidis floridae, Herba Psiloti Nudi, Folium daphnes odorae He Herba Siegesbeckiae decontamination, clean, mix thoroughly with Sucus Zingberis, infiltrate 20 minutes, take out, put into pot Steam by water bath 15 minutes, take out, dry;
(4) Carnis Vulpes is cleaned, mix thoroughly with vinegar and Rhizoma Zingiberis, moistening 10 minutes, Carnis Vulpes and Rhizoma Zingiberis are poured into boiling water to scald 10 minutes, pull out, dry in the air cool, diced, decoct with water together with Herba Damnacanthi (amount of water is 8 times of boiled crude drug quality) with the Cortex Magnoliae Officinalis cleaned, Caulis Lonicerae, Semen Strychni, Poria, Polyporus, big fire is boiled rear little fire and is decocted 36 minutes, decoct three times altogether, merge three gained medicinal liquids, concentrating under reduced pressure, dry, pulverize, make medicated powder;
(5) step (1) (2) (3) made crude drug was pulverized 140 mesh sieves, and mixed with step (4) made medicated powder, obtained mixed powder, by made mixed powder, is processed into tablet dosage form according to the preparation for processing of tablet, obtains tablet.
Model case: xxx, man, 61 years old.Main suit: suffer from gout 3 years, there are 6 tophus in ears exterior feature portion, diet is pungent, after alcohol type F&B, red and swollen heat pain appears in right crus of diaphragm metatarsophalangeal joints, there is slight deformation local, surface skin burns, with dry mouth and tougue, examination in hospital, red tongue, yellow and greasy fur, stringy and rolling pulse, urinate acid up to 1048.4 μm of ol/L, and erythrocyte sedimentation rate 29mm/h, is diagnosed as acute gout.
Take a kind of formulation tablet for the treatment of gout of the present embodiment gained, adopt every day 2 times, each 4, with warm water delivery service, 15 days courses for the treatment of.After taking 4 days, the symptoms such as metatarsophalangeal joints red and swollen heat pain obviously alleviates, and surface skin is normal, xerostomia are eliminated, after taking a course for the treatment of, redness and swelling of joints burning pain is eliminated completely, without other malaise symptoms, checks acid of urinating and is down to 547 μm of ol/L, consolidate after taking a course for the treatment of, patient is without malaise symptoms, and clinical cure, follows up a case by regular visits in half a year and do not recur.
embodiment 4treat a preparation for gout, be prepared from (every part of 10g) primarily of following bulk drugs: Cortex Magnoliae Officinalis 16 parts, 14 parts, pallet, Caulis Lonicerae 14 parts, Celastrus aceleatus Merr 15 parts, Semen Strychni 12 parts, 14 parts, Poria, Radix clematidis floridae 14 parts, great Ye Rhizoma Curculiginis 17 parts, Polyporus 13 parts, Cortex erythrinae 15 parts, Herba Psiloti Nudi 12 parts, Folium daphnes odorae 15 parts of Herba Siegesbeckiaes 12 parts, Carnis Vulpes 9 parts, Herba Damnacanthi 13 parts.
A kind of preparation method for the treatment of the preparation pill of gout is:
(1) get pallet decontamination, clean, infiltrate with clear water, section, yellow wine and hydromel mixing are made mixed liquor, and pallet sheet dips in mixed liquor and is placed on fire and dries, and repetitive operation three times, after drying for the last time, dries in the air cool;
(2) by Celastrus aceleatus Merr, great Ye Rhizoma Curculiginis and Cortex erythrinae decontamination, clean, boil with yellow wine, after wine exhausts, take out, wrap up three layers, be placed in hot ash with wet toilet paper, when simmering dried-up to outer paper, take out, removing paper, dries;
(3) get Radix clematidis floridae, Herba Psiloti Nudi, Folium daphnes odorae He Herba Siegesbeckiae decontamination, clean, mix thoroughly with Sucus Zingberis, infiltrate 20 minutes, take out, put into pot Steam by water bath 15 minutes, take out, dry;
(4) Carnis Vulpes is cleaned, mix thoroughly with vinegar and Rhizoma Zingiberis, moistening 10 minutes, Carnis Vulpes and Rhizoma Zingiberis are poured into boiling water to scald 10 minutes, pull out, dry in the air cool, diced, decoct with water together with Herba Damnacanthi (amount of water is 8 times of boiled crude drug quality) with the Cortex Magnoliae Officinalis cleaned, Caulis Lonicerae, Semen Strychni, Poria, Polyporus, big fire is boiled rear little fire and is decocted 36 minutes, decoct three times altogether, merge three gained medicinal liquids, concentrating under reduced pressure, dry, pulverize, make medicated powder;
(5) step (1) (2) (3) made crude drug was pulverized 100 mesh sieves, and mixed with step (4) made medicated powder, obtained mixed powder, adds refined honey and water, and ball block, ball bar, and gradation, round are dry, obtain pill.
Model case: xxx, female, 50 years old.Main suit: suffer from goat 1 year, nearly one week two lower limb pain, ankle arthrosis and toe joint red and swollen heat pain, tenderness, local swelling is out of shape, joint stuffiness, especially to attach most importance to night, yellowish or reddish urine, examination in hospital, dark tongue quality, yellow and thin fur, thready and hesitant pulse, urinate acid 724.2 μm of ol/L, is diagnosed as gout recurrence.
Take a kind of preparation pill for the treatment of gout of the present embodiment gained, adopt every day 2 times, each 4, with warm water delivery service, 15 days courses for the treatment of.After taking 3 days, redness and swelling of joints burning pain obviously alleviates, and after taking a course for the treatment of, patient articular's swelling, burning pain is eliminated completely, and consolidate after taking one week, drug withdrawal, check, acid of urinating is 346.7 μm of ol/L, and patient fully recovers, and follows up a case by regular visits to and do not recur in 1 year.
embodiment 5treat a preparation for gout, be prepared from (every part of 10g) primarily of following bulk drugs: Cortex Magnoliae Officinalis 15 parts, 12 parts, pallet, Caulis Lonicerae 13 parts, Celastrus aceleatus Merr 12.5 parts, Semen Strychni 10.5 parts, 13.5 parts, Poria, Radix clematidis floridae 12.5 parts, great Ye Rhizoma Curculiginis 15.5 parts, Polyporus 11 parts, Cortex erythrinae 13.5 parts, Herba Psiloti Nudi 11 parts, Folium daphnes odorae 14 parts of Herba Siegesbeckiaes 11.5 parts, Carnis Vulpes 8 parts, Herba Damnacanthi 11.5 parts.
A kind of preparation method for the treatment of the preparation decoction of gout is:
(1) get pallet decontamination, clean, infiltrate with clear water, section, yellow wine and hydromel mixing are made mixed liquor, and pallet sheet dips in mixed liquor and is placed on fire and dries, and repetitive operation three times, after drying for the last time, dries in the air cool;
(2) by Celastrus aceleatus Merr, great Ye Rhizoma Curculiginis and Cortex erythrinae decontamination, clean, boil with yellow wine, after wine exhausts, take out, wrap up three layers, be placed in hot ash with wet toilet paper, when simmering dried-up to outer paper, take out, removing paper, dries;
(3) get Radix clematidis floridae, Herba Psiloti Nudi, Folium daphnes odorae He Herba Siegesbeckiae decontamination, clean, mix thoroughly with Sucus Zingberis, infiltrate 20 minutes, take out, put into pot Steam by water bath 15 minutes, take out, dry;
(4) Carnis Vulpes is cleaned, mix thoroughly with vinegar and Rhizoma Zingiberis, moistening 10 minutes, Carnis Vulpes and Rhizoma Zingiberis are poured in boiling water and scalds 10 minutes, pull out, dry in the air cool, diced, decoct with water (amount of water is 8 times of total raw material medicine quality) together with the Cortex Magnoliae Officinalis cleaned, Caulis Lonicerae, Semen Strychni, Poria, Polyporus, Herba Damnacanthi and step (1) (2) (3) made crude drug, big fire is boiled rear little fire and is decocted 36 minutes, filter, collect medicinal liquid, obtain decoction.
test example 1a kind of clinical practice for the treatment of the preparation (embodiment 5) of gout of gained of the present invention:
In June, 2012, in December ,-2014, filtered out 312 examples in the patient with gout of 6 hospitals treatment, wherein women 148 example, metastatic tumors in male: An analysis of 164 cases, age 28-62 year, the mean age (43.7 ± 5.2) year ,-8 years half a year of the course of disease, average course of disease (4.2 ± 0.8) year.Inclusive criteria: dialuric acid enzymatic assays, Level of Serum Uric Acid > 420 μm of ol/L, and the diagnostic criteria meeting the constitutional acute gout of American Rheumatism Association's formulation in 1977.Get rid of in nearly 1 month take affect uric acid, blood glucose and blood lipid metabolism medicine, anti-inflammatory agent or immunosuppressant person, with joint severe deformity, stiff person, various active chronic inflammation or rheumatism immunity patient, trimester of pregnancy or women breast-feeding their children and merge the patient that other system serious diseases person, data full person, psychotic etc. affect this result of study.
Patient is divided into two groups at random, experimental group 180 example and matched group 132 routine, two groups in sex, age, the course of disease, the state of an illness etc. without significant difference (
p> 0.05), there is comparability.Experimental group takes products obtained therefrom of the present invention, and take every day twice (warm), each 350m1-500m1(adjusts to some extent depending on concrete condition), 15 days courses for the treatment of, treat two courses for the treatment of.Matched group takes other medicine (conventional medication such as gout stator, colchicines tablets, allopurinol tablet).Period in a medicine carries out Continuous Observation to two groups of patients, record symptom and change.Detect the change of serum Uric Acid Concentration before and after two groups of treatments.
Curative effect situation criterion: cure: clinical symptoms and sign disappear completely, joint function recovery is normal, and blood uric acid and erythrocyte sedimentation rate index recover normal, normal renal function; Effective: clinical cardinal symptom disappears or obviously improves, and function of joint recovers normal substantially, blood uric acid and erythrocyte sedimentation rate index recover normal, normal renal function; Effective: main clinic symptoms is improved, function of joint takes a turn for the better, and Uric Acid Content and erythrocyte sedimentation rate reduce, and renal function takes a turn for the better; Invalid: clinical symptoms is without improvement, and physical and chemical index checks unchanged.
Table 1 a liang group patient treatment outcome compare (n/%)
Through treatment, experimental group cures 89 examples, effective 52 examples, effective 34 examples, experimental group total effective rate 97.2%; Matched group cures 33 examples, effective 54 examples, and effective 26 examples, matched group total effective rate is that 85.7%, two groups of therapeutic outcomes are compared known, and the therapeutic effect of experimental group is better than matched group.All there is not any untoward reaction in treatments period two groups of patients.
The expectorant of Cortex Magnoliae Officinalis dampness is had, pallet reducing swelling and alleviating pain, Caulis Lonicerae heat-clearing and toxic substances removing in formula of the present invention, Celastrus aceleatus Merr expelling wind and removing dampness, Semen Strychni removing obstruction in the collateral to relieve pain, Poria promoting diuresis to eliminate damp pathogen, Radix clematidis floridae diuresis dredging collateral, the calm spleen invigorating of great Ye Rhizoma Curculiginis, Polyporus promoting diuresis to eliminate damp pathogen, Cortex erythrinae channels sootheing and network vessel quickening, Herba Psiloti Nudi promoting blood circulation to remove obstruction in the collateral, Folium daphnes odorae reducing swelling and alleviating pain Herba Siegesbeckiae wind-damp dispelling, Carnis Vulpes is mended in continuous warming up, Herba Damnacanthi promoting blood circulation and detumescence, plurality of Chinese raw material, collaborative performance effect, can play the effect such as promoting diuresis to eliminate damp pathogen, removing obstruction in the collateral to relieve pain.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.
Claims (10)
1. treat a preparation for gout, it is characterized in that, be prepared from primarily of following bulk drugs, be mass parts: Cortex Magnoliae Officinalis 12-18, pallet 8-16, Caulis Lonicerae 11-15, Celastrus aceleatus Merr 9-16, Semen Strychni 7-14, Poria 11-16, Radix clematidis floridae 9-16, great Ye Rhizoma Curculiginis 13-18, Polyporus 7-15, Cortex erythrinae 11-16, Herba Psiloti Nudi 9-13, Folium daphnes odorae 12-16 Herba Siegesbeckiae 10-13, Carnis Vulpes 6-10, Herba Damnacanthi 8-15.
2. a kind of preparation for the treatment of gout as claimed in claim 1, it is characterized in that, Cortex Magnoliae Officinalis 14-16, pallet 10-14, Caulis Lonicerae 12-14, Celastrus aceleatus Merr 10-15, Semen Strychni 9-12, Poria 12-14, Radix clematidis floridae 11-14, great Ye Rhizoma Curculiginis 14-17, Polyporus 9-13, Cortex erythrinae 12-15, Herba Psiloti Nudi 10-12, Folium daphnes odorae 13-15, Herba Siegesbeckiae 11-12, Carnis Vulpes 7-9, Herba Damnacanthi 10-13 is (preferred, Cortex Magnoliae Officinalis 15, pallet 12, Caulis Lonicerae 13, Celastrus aceleatus Merr 12.5, Semen Strychni 10.5, Poria 13.5, Radix clematidis floridae 12.5, great Ye Rhizoma Curculiginis 15.5, Polyporus 11, Cortex erythrinae 13.5, Herba Psiloti Nudi 11, Folium daphnes odorae 14, Herba Siegesbeckiae 11.5, Carnis Vulpes 8, Herba Damnacanthi 11.5).
3. a kind of preparation for the treatment of gout as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable decoction, its preparation method is:
(1) get pallet decontamination, clean, infiltrate with clear water, section, yellow wine and hydromel mixing are made mixed liquor, and pallet sheet dips in mixed liquor and is placed on fire and dries, and repetitive operation three times, after drying for the last time, dries in the air cool;
(2) by Celastrus aceleatus Merr, great Ye Rhizoma Curculiginis and Cortex erythrinae decontamination, clean, boil with yellow wine, after wine exhausts, take out, wrap up three layers, be placed in hot ash with wet toilet paper, when simmering dried-up to outer paper, take out, removing paper, dries;
(3) get Radix clematidis floridae, Herba Psiloti Nudi, Folium daphnes odorae He Herba Siegesbeckiae decontamination, clean, mix thoroughly with Sucus Zingberis, infiltrate 20 minutes, take out, put into pot Steam by water bath 15 minutes, take out, dry;
(4) Carnis Vulpes is cleaned, mix thoroughly with vinegar and Rhizoma Zingiberis, moistening 10 minutes, Carnis Vulpes and Rhizoma Zingiberis are poured in boiling water and scalds 10 minutes, pull out, dry in the air cool, diced, decoct with water together with the Cortex Magnoliae Officinalis cleaned, Caulis Lonicerae, Semen Strychni, Poria, Polyporus, Herba Damnacanthi and step (1) (2) (3) made crude drug, big fire is boiled rear little fire and is decocted 30-42 minute (preferred, 34-38 minute decocted by little fire; Be more preferably, little fire decocts 36 minutes), filter, collect medicinal liquid, obtain decoction.
4. a kind of preparation method for the treatment of the preparation decoction of gout as claimed in claim 3, is characterized in that, step (4) amount of water be the 7-9 of total raw material medicine quality doubly (preferred, amount of water be the 7.5-8.5 of total raw material medicine quality doubly; Be more preferably, amount of water is 8 times of total raw material medicine quality).
5. a kind of preparation for the treatment of gout as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable capsule, its preparation method is:
(1) get pallet decontamination, clean, infiltrate with clear water, section, yellow wine and hydromel mixing are made mixed liquor, and pallet sheet dips in mixed liquor and is placed on fire and dries, and repetitive operation three times, after drying for the last time, dries in the air cool;
(2) by Celastrus aceleatus Merr, great Ye Rhizoma Curculiginis and Cortex erythrinae decontamination, clean, boil with yellow wine, after wine exhausts, take out, wrap up three layers, be placed in hot ash with wet toilet paper, when simmering dried-up to outer paper, take out, removing paper, dries;
(3) get Radix clematidis floridae, Herba Psiloti Nudi, Folium daphnes odorae He Herba Siegesbeckiae decontamination, clean, mix thoroughly with Sucus Zingberis, infiltrate 20 minutes, take out, put into pot Steam by water bath 15 minutes, take out, dry;
(4) Carnis Vulpes is cleaned, mix thoroughly with vinegar and Rhizoma Zingiberis, moistening 10 minutes, Carnis Vulpes and Rhizoma Zingiberis are poured into boiling water to scald 10 minutes, pull out, dry in the air cool, diced, decoct with water (amount of water is 8 times of total raw material medicine quality) together with the Cortex Magnoliae Officinalis cleaned, Caulis Lonicerae, Semen Strychni, Poria, Polyporus, Herba Damnacanthi and step (1) (2) (3) made crude drug, big fire is boiled rear little fire and is decocted, and decocts three times altogether, merges three gained medicinal liquids, concentrating under reduced pressure, dry, pulverize, make medicated powder, incapsulate, obtain capsule.
6. a kind of preparation method for the treatment of the preparation capsule of gout as claimed in claim 5, is characterized in that, step (4) big fire is boiled rear little fire and decocted 30-42 minute (preferred, 34-38 minute decocted by little fire; Be more preferably, little fire decocts 36 minutes).
7. a kind of preparation for the treatment of gout as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable tablet, its preparation method is:
(1) get pallet decontamination, clean, infiltrate with clear water, section, yellow wine and hydromel mixing are made mixed liquor, and pallet sheet dips in mixed liquor and is placed on fire and dries, and repetitive operation three times, after drying for the last time, dries in the air cool;
(2) by Celastrus aceleatus Merr, great Ye Rhizoma Curculiginis and Cortex erythrinae decontamination, clean, boil with yellow wine, after wine exhausts, take out, wrap up three layers, be placed in hot ash with wet toilet paper, when simmering dried-up to outer paper, take out, removing paper, dries;
(3) get Radix clematidis floridae, Herba Psiloti Nudi, Folium daphnes odorae He Herba Siegesbeckiae decontamination, clean, mix thoroughly with Sucus Zingberis, infiltrate 20 minutes, take out, put into pot Steam by water bath 15 minutes, take out, dry;
(4) Carnis Vulpes is cleaned, mix thoroughly with vinegar and Rhizoma Zingiberis, moistening 10 minutes, Carnis Vulpes and Rhizoma Zingiberis are poured into boiling water to scald 10 minutes, pull out, dry in the air cool, diced, decoct with water together with Herba Damnacanthi (amount of water is 8 times of boiled crude drug quality) with the Cortex Magnoliae Officinalis cleaned, Caulis Lonicerae, Semen Strychni, Poria, Polyporus, big fire is boiled rear little fire and is decocted 30-42 minute (preferred, 34-38 minute decocted by little fire; Be more preferably, little fire decocts 36 minutes), decoct three times altogether, merge three gained medicinal liquids, concentrating under reduced pressure, dry, pulverize, and makes medicated powder;
(5) pulverized and sieved by step (1) (2) (3) made crude drug, mix with step (4) made medicated powder, obtained mixed powder, by made mixed powder, is processed into tablet dosage form according to the preparation for processing of tablet, obtains tablet.
8. a kind of preparation method for the treatment of the formulation tablet of gout as claimed in claim 7, is characterized in that, step (5) pulverized 120-160 mesh sieve (preferred, pulverized 130-150 mesh sieve; Be more preferably, pulverized 140 mesh sieves).
9. a kind of preparation for the treatment of gout as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable pill, its preparation method is:
(1) get pallet decontamination, clean, infiltrate with clear water, section, yellow wine and hydromel mixing are made mixed liquor, and pallet sheet dips in mixed liquor and is placed on fire and dries, and repetitive operation three times, after drying for the last time, dries in the air cool;
(2) by Celastrus aceleatus Merr, great Ye Rhizoma Curculiginis and Cortex erythrinae decontamination, clean, boil with yellow wine, after wine exhausts, take out, wrap up three layers, be placed in hot ash with wet toilet paper, when simmering dried-up to outer paper, take out, removing paper, dries;
(3) get Radix clematidis floridae, Herba Psiloti Nudi, Folium daphnes odorae He Herba Siegesbeckiae decontamination, clean, mix thoroughly with Sucus Zingberis, infiltrate 20 minutes, take out, put into pot Steam by water bath 15 minutes, take out, dry;
(4) Carnis Vulpes is cleaned, mix thoroughly with vinegar and Rhizoma Zingiberis, moistening 10 minutes, Carnis Vulpes and Rhizoma Zingiberis are poured into boiling water to scald 10 minutes, pull out, dry in the air cool, diced, decoct with water together with Herba Damnacanthi (amount of water is 8 times of boiled crude drug quality) with the Cortex Magnoliae Officinalis cleaned, Caulis Lonicerae, Semen Strychni, Poria, Polyporus, big fire is boiled rear little fire and is decocted 30-42 minute (preferred, 34-38 minute decocted by little fire; Be more preferably, little fire decocts 36 minutes), decoct three times altogether, merge three gained medicinal liquids, concentrating under reduced pressure, dry, pulverize, and makes medicated powder;
(5) pulverized and sieved by step (1) (2) (3) made crude drug, mix with step (4) made medicated powder, obtained mixed powder, adds refined honey and water, and ball block, ball bar, and gradation, round are dry, obtain pill.
10. a kind of preparation method for the treatment of the preparation pill of gout as claimed in claim 9, is characterized in that, step (5) pulverized 80-120 mesh sieve (preferred, pulverized 90-110 mesh sieve; Be more preferably, pulverized 100 mesh sieves).
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1927330A (en) * | 2006-09-05 | 2007-03-14 | 广州固志医药科技有限公司 | Chinese medicine composition for treating gout and preparing method thereof |
| CN101524494A (en) * | 2009-05-05 | 2009-09-09 | 陆玉敏 | Drug for treating gout |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1927330A (en) * | 2006-09-05 | 2007-03-14 | 广州固志医药科技有限公司 | Chinese medicine composition for treating gout and preparing method thereof |
| CN101524494A (en) * | 2009-05-05 | 2009-09-09 | 陆玉敏 | Drug for treating gout |
Non-Patent Citations (1)
| Title |
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| 杨中华等: "健脾清热利湿通络方治疗急性痛风性关节炎60例临床分析", 《中国现代医药杂志》 * |
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Address after: 678000 Longyang District of Baoshan city in Yunnan Province, City Road No. 65, District 1 building 2-801 Applicant after: Li Jun Address before: Huashan Zhen Chang Jia Zhuang 250000 Licheng District Shandong city of Ji'nan province No. 8 Applicant before: Li Jun |
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