CN104877183A - Ganoderma-antradiacomphora polysaccharide and membrane permeation preparation process thereof - Google Patents
Ganoderma-antradiacomphora polysaccharide and membrane permeation preparation process thereof Download PDFInfo
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- CN104877183A CN104877183A CN201510287568.0A CN201510287568A CN104877183A CN 104877183 A CN104877183 A CN 104877183A CN 201510287568 A CN201510287568 A CN 201510287568A CN 104877183 A CN104877183 A CN 104877183A
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- camphor tree
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Abstract
The invention discloses a ganoderma-antradiacomphora polysaccharide and a membrane permeation preparation process thereof. The ganoderma-antradiacomphora polysaccharide is made of, by weight, 5-60% of ganoderma polysaccharides, 5-60% of antradiacomphora polysaccharides, 5-40% of cordyceps sinensis polysaccharides and 5-30% of codonopsis polysaccharides by culturing, membrane permeation and filtering, purification, drying, crushing, compounding and filling. The ganoderma-antradiacomphora polysaccharide which belongs to curative health-care dissoluble medicines is applicable to sub-healthy people and effective in blood enriching and dryness moistening, liver protection, blood pressure reduction, blood fat reduction, free radicals scavenging and anti-oxidation, anti-aging, , antibacterial, antiviral, anti-myocardial ischemia functions and has efficacies of reinforcing kidney, strengthening tendons and bones and treating copos, waist and knee pains, spontaneous sweating, nght sweating and the like.
Description
Technical field:
The present invention relates to a kind of immunity moderation power, improve sanguimotor health instant powder, no side effects, particularly the clever camphor tree polysaccharide of one and membrane permeation preparation technology thereof.
Background technology:
At present, the living environment due to people is subject to Air haze, water and food by the impact of agricultural chemicals, pollution by chemical fertilizer etc., and occurred large quantities of sub-health population, made the immunity degradation of human body, various disease significantly rises.
Summary of the invention:
The object of the invention is to overcome above-mentioned deficiency, provide a kind of and improve body immunity, reconcile one spirit camphor tree polysaccharide and the membrane permeation preparation technology thereof of sub-health population physique
The object of the present invention is achieved like this, and it forms by by ganoderan, camphor tree sesame polysaccharide, Cordyceps polysaccharide, Radix Codonopsis polysaccharide, and its weight percent is: ganoderan 5-60%, camphor tree sesame polysaccharide 5-60%, Cordyceps Polysaccharide 5-40%, Radix Codonopsis polysaccharide 5-30%.
The concrete preparation technology of Cordyceps Polysaccharide, ganoderan, camphor tree sesame polysaccharide is respectively: bacterial classification → slant culture 10-20 days → shake-flask culture 1-5 days → fermentor cultivation 1-5 days → membrane permeation filters out mycelium, filter out the obtained three kinds of fungus polysaccharides of mycelium → purification polysaccharide → drying → pulverizing in nutrient solution, it is as follows that Radix Codonopsis polysaccharide refines complete processing simultaneously: and raw material is selected → cleaning → pulverizings → membrane permeation filters → concentrated → purify → and dry → pulverizing obtains; Above-mentioned obtained Cordyceps polysaccharide, ganoderan, camphor tree sesame polysaccharide, Radix Codonopsis polysaccharide Homogeneous phase mixing in proportion, successively through oven dry, sterilising treatment, obtained clever camphor tree polysaccharide.
Culture temperature at 0 DEG C-68 DEG C, nutrient solution pH value at 4.9-7.8, grinding particle size 90 order-300 order.
Advantage of the present invention is, technique is simple, without any side effects, enriching blood and moistening for dryness, liver protecting, hypotensive, reducing blood-fat, anti-oxidant, anti-ageing, scavenging free radicals, antibacterial, antiviral, resist myocardial ischemia successful, has replenishing kidney-YIN in addition, strengthens muscles and bones, the effect such as copos, soreness of waist and knee joint, spontaneous sweating.
The production of spirit camphor tree polysaccharide belongs to aerobic fermentation, adopts liquid submerged fermentation technology.So-called liquid submerged fermentation technology is exactly access bacterial classification in the sealed fermentation tank that aseptic liquid nutrient medium is housed, and passes into sterile air and stirs, fermenting.Be characterized in: be easy to realize heavy industrialization, stdn, automatic production, production efficiency is high; Effectively prevent the pesticidal contamination in traditional method and heavy metals exceeding standard problem.
Spirit camphor tree polysaccharide has no side effect to human non-toxic, has abandoned the traditional concept of " being medicine three points of poison ".This is because intracellular polyse inherently forms the constituent of life cells, and exocellular polysaccharide has functions such as strengthening immunity, and expert is referred to as " sugared quilt ".
The clever camphor tree polysaccharide that liquid submerged fermentation technology is produced, its main component is polysaccharide, other bioactive ingredients has triterpenes, saponin(e, adenosine, super oxygen disproportionation ferment, glycoprotein, amino acid, sterol, organic acid, trace elements zn, Mg, Cu, Co, Mn, Cr, Fe, Mo etc., this will significantly reduce sub-health population ratio.
As everyone knows, glossy ganoderma belongs to medicine-feeding at " Chinese edible medicinal fungus ", and due to growing environment restriction, it yields poorly, bioactive ingredients content is low, the cycle is long, can not meet the needs of sub-health population in 7,200,000,000 populations of the whole world far away.Present employing liquid submerged fermentation technology, just can address these problems, and this is the happiness of the mankind.
Embodiment:
Embodiment one:
Spirit camphor tree polysaccharide is the health instant powder of ganoderan, camphor tree sesame polysaccharide, Cordyceps Polysaccharide, Radix Codonopsis polysaccharide composition, ganoderan 5%, camphor tree sesame polysaccharide 50%, Cordyceps Polysaccharide 40%, Radix Codonopsis polysaccharide 5% by weight percentage.
The bacterial classification of camphor tree sesame polysaccharide, ganoderan, Cordyceps Polysaccharide is through slant culture, shake-flask culture, fermentor cultivation, culture temperature is at 40 DEG C-68 DEG C, nutrient solution pH value is at 4.9-7.8, grinding particle size 90 order, again through membrane filtration, purification, drying, the obtained three kinds of fungus polysaccharides of pulverizing, Radix Codonopsis polysaccharide is selected, cleaning, pulverizing, water extraction, alcohol extracting, concentrated, purify, dry, pulverize obtained, above-mentioned obtained four kinds of polysaccharide Homogeneous phase mixing in proportion, successively through oven dry, sterilising treatment, obtained clever camphor tree polysaccharide.
Embodiment two:
Be that proportioning raw materials of the present invention is different from embodiment one difference.By weight percentage, ganoderan 60%, camphor tree sesame polysaccharide 5%, Cordyceps Polysaccharide 20%, Radix Codonopsis polysaccharide 15%.The bacterial classification of camphor tree sesame polysaccharide, ganoderan, Cordyceps Polysaccharide is through slant culture, shake-flask culture, fermentor cultivation, culture temperature is at 0 DEG C-68 DEG C, nutrient solution pH value is at 4.9-7.8, grinding particle size 200 order, again through membrane filtration, purification, drying, the obtained three kinds of fungus polysaccharides of pulverizing, Radix Codonopsis polysaccharide is selected, cleaning, pulverizing, water extraction, alcohol extracting, concentrated, purify, dry, pulverize obtained, above-mentioned obtained four kinds of polysaccharide Homogeneous phase mixing in proportion, successively through oven dry, sterilising treatment, obtained clever camphor tree polysaccharide.
Embodiment three:
Be that proportioning raw materials of the present invention is different from embodiment one difference.By weight percentage, ganoderan %, camphor tree sesame polysaccharide 60%, Cordyceps Polysaccharide 5%, Radix Codonopsis polysaccharide 30%.The bacterial classification of camphor tree sesame polysaccharide, ganoderan, Cordyceps Polysaccharide is through slant culture, shake-flask culture, fermentor cultivation, culture temperature is at 0 DEG C-68 DEG C, nutrient solution pH value is at 4.9-7.8, grinding particle size 300 order, again through membrane filtration, purification, drying, the obtained three kinds of fungus polysaccharides of pulverizing, Radix Codonopsis polysaccharide is selected, cleaning, pulverizing, water extraction, alcohol extracting, concentrated, purify, dry, pulverize obtained, above-mentioned obtained four kinds of polysaccharide Homogeneous phase mixing in proportion, successively through oven dry, sterilising treatment, obtained clever camphor tree polysaccharide.
Claims (4)
1. a clever camphor tree polysaccharide and membrane permeation preparation technology thereof, it is characterized in that: it is made up of ganoderan, camphor tree sesame polysaccharide, Cordyceps Polysaccharide, Radix Codonopsis polysaccharide, its weight percent is: ganoderan 5-60%, camphor tree sesame polysaccharide 5-60%, Cordyceps Polysaccharide 5-40%, Radix Codonopsis polysaccharide 5-30%.
2. the clever camphor tree polysaccharide of one according to claim 1 and membrane permeation preparation technology thereof, is characterized in that:
The liquid submerged fermentation manufacture craft of the first step, fungus polysaccharide, comprise Cordyceps Polysaccharide, ganoderan, camphor tree sesame polysaccharide, specific as follows: bacterial classification → slant culture 10-20 days → shake-flask culture 1-5 days → fermentor cultivation 1-5 days → membrane permeation filters out mycelium, filters out the obtained three kinds of fungus polysaccharides of mycelium → purification polysaccharide → drying → pulverizing in nutrient solution simultaneously;
It is as follows that second step, Radix Codonopsis polysaccharide refine complete processing: and raw material is selected → cleaning → pulverizings → membrane permeation filters → concentrated → purify → and dry → pulverizing obtains;
3rd step, above-mentioned obtained Cordyceps Polysaccharide, ganoderan, camphor tree sesame polysaccharide, Radix Codonopsis polysaccharide Homogeneous phase mixing in proportion, successively through drying, sterilising treatment, this clever camphor tree polysaccharide obtained.
3. the clever camphor tree polysaccharide of one according to claim 2 and membrane permeation preparation technology thereof, is characterized in that: culture temperature at 0 DEG C-68 DEG C, nutrient solution pH value at 4.9-7.8, grinding particle size 90 order-300 order.
4. the clever camphor tree polysaccharide of one according to claim 2 and membrane permeation preparation technology thereof, is characterized in that: the biological activity content such as polysaccharide, triterpene, saponin(e by weight can more than 85%.
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106038705A (en) * | 2016-08-10 | 2016-10-26 | 翔天农业开发集团股份有限公司 | Antihypertensive health-care capsule and preparation method thereof |
| CN106074713A (en) * | 2016-08-10 | 2016-11-09 | 翔天农业开发集团股份有限公司 | A kind of antihypertensive health care oral liquid and preparation method thereof |
| CN106265936A (en) * | 2016-08-10 | 2017-01-04 | 翔天农业开发集团股份有限公司 | A kind of antihypertensive health care electuary and preparation method thereof |
| CN110713550A (en) * | 2018-07-12 | 2020-01-21 | 浙江省亚热带作物研究所 | Method for preparing refined polysaccharide with antibacterial activity by using cordyceps culture |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106038705A (en) * | 2016-08-10 | 2016-10-26 | 翔天农业开发集团股份有限公司 | Antihypertensive health-care capsule and preparation method thereof |
| CN106074713A (en) * | 2016-08-10 | 2016-11-09 | 翔天农业开发集团股份有限公司 | A kind of antihypertensive health care oral liquid and preparation method thereof |
| CN106265936A (en) * | 2016-08-10 | 2017-01-04 | 翔天农业开发集团股份有限公司 | A kind of antihypertensive health care electuary and preparation method thereof |
| CN110713550A (en) * | 2018-07-12 | 2020-01-21 | 浙江省亚热带作物研究所 | Method for preparing refined polysaccharide with antibacterial activity by using cordyceps culture |
| CN110713550B (en) * | 2018-07-12 | 2022-03-15 | 浙江省亚热带作物研究所 | Method for preparing refined polysaccharide with antibacterial activity by using cordyceps culture |
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