CN104872149A - 4-p-phenoxy phenoxy methyl structure-containing 1,3-dioxolane compound and amide insecticide composition - Google Patents
4-p-phenoxy phenoxy methyl structure-containing 1,3-dioxolane compound and amide insecticide composition Download PDFInfo
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Abstract
The present invention discloses a 4-p-phenoxy phenoxy methyl structure-containing 1,3-dioxolane compound and amide insecticide composition, wherein the active components of the composition comprise a 4-p-phenoxy phenoxy methyl structure-containing 1,3-dioxolane compound and an amide insecticide, and the amide insecticide is one or a plurality of materials selected from tolfenpyrad, flonicamid, chlorantraniliprole, flubendiamide, cyantraniliprole, cyantraniliprole, cyhalodiamide, JS 9117 and the like. The composition can be used for pests or action in environments, habitats or storage areas of pests. According to the present invention, the efficacy of the composition of the present invention is significantly higher than the efficacy of the single-dose product, such that the preparation consumption is reduced, the resistance risk of pests is effectively reduced, and the significant synergy effect is provided after the composition is compounded.
Description
Technical field
The present invention relates to a kind of composition pesticide, particularly relate to a kind of 4-that contains to 1 of phenoxy-phenoxy methyl structural, 3-dioxolane compound and amide-type insecticide composition, and the application of described composition in insect or its environment, habitat or storage areas.
Background technology
The use of agricultural chemicals has very long history, has played huge effect in the process of mankind's nature remodeling.Facilitate the great development of agricultural, bring huge economic benefit to the mankind.But in the agricultural production in modern times, due to the transformation of environment, weather, the damage by disease and insect of same crop often occurs simultaneously, use existing single insecticide cannot pest control, existing insecticide not only delays work and easily causes missing of control opportunity, thus cause needing larger pesticide dosage just can reach insecticidal effect, cause quality of agricultural product to decline.In recent years, due to single and not Scientific Usage of Drugs, cause insect, the pesticide resistance of evil mite to various active component medicament improve further, directly cause that the pesticide producing cost of peasant improves, the destruction etc. of environmental pollution and ecotope.
Amide-type insecticide is due to the structure of its uniqueness, spectrum preventive effect is had to lepidoptera pest, be suitable for the control that existing insecticide produces the insect of resistance, control for larva has outstanding preventive effect, but it is limited to adult preventive effect, and there is no ovicidal action, slightly conducted by xylem after in infiltration plant body, and there is the effect of resistance of rainwater washing against.
But amide-type insecticide at present, as high in fipronil bisamide, Rynaxypyr price, therefore its usable floor area is confined to, on the higher Vegetable of economic value added, cannot be widely used, and can not realize the widespread adoption in crop pests control.
Patent CN101755750A discloses a kind of insecticide containing fipronil bisamide, this insecticide effective active component content is 1% ~ 80%, and auxiliary agent and excipient is added in described insecticide, comprise dispersant, wetting agent, stabilizing agent, defoamer, antifreeze or filler.But because in obtained insecticide, active ingredient is comparatively single, therefore its control efficiency for the insect outside Lepidoptera is not good.
Soon quick-acting in order to develop, the lasting period is longer, and the agricultural chemicals that use cost is lower, extend the amide-type insecticide life-span commercially, make it still keep higher competitiveness.Need further to study novel pesticide complex composition.
Summary of the invention
The invention provides a kind of newly by 4-to 1 of phenoxy-phenoxy methyl structural, the composition pesticide of 3-dioxolane compound and amide-type pesticide compositional, with the problem that the synergistic effect of the composition pesticide solving the composite rear gained existed in prior art is poor.
A first aspect of the present invention provides a kind of 4-that contains to the DOX compounds of phenoxy-phenoxy methyl structural and amide-type insecticide composition, and wherein, the active ingredient of composition comprises component A and B component.
Wherein, described component A is preferably containing 4-the DOX compounds of phenoxy-phenoxy methyl structural.
Wherein, described B component is preferably amide-type insecticide.
Wherein, the weight ratio of described component A and described B component is preferably 99:1-1:99.
The contain 4-DOX compounds to phenoxy-phenoxy methyl structural of the present invention one comparatively described in preferred embodiment is preferably the structure shown in structural formula (I):
Wherein, R is selected from alkyl, thiazolinyl, cycloalkyl and aryl; Be more preferably the alkyl of C1-C10, the aromatic radical of C6-C15, the cycloalkyl of C3-C10, can also the alkyl of more preferably C1-C6, the aromatic radical of C6-C10, the cycloalkyl of C3-C8, as methyl, ethyl, propyl group, isopropyl, normal-butyl, phenyl, benzyl, naphthyl, cyclopropyl, cyclopenta, cyclohexyl etc.
Described most preferably is 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX containing the DOX compounds of 4-to phenoxy-phenoxy methyl structural.
The present invention one is comparatively in preferred embodiment, described containing amide-type insecticide be selected from Tolfenpyrad, flonicamid, Rynaxypyr, fipronil bisamide, cyanogen insect amide, bromine cyanogen insect amide, fluorine cyanogen insect amide or thiophene insect amide one or more, be more preferably in Tolfenpyrad, flonicamid, Rynaxypyr, fipronil bisamide, cyanogen insect amide, bromine cyanogen insect amide or fluorine cyanogen insect amide any one.
In a preferred embodiment of the present invention, described component A and the weight ratio of B component are preferably 80:1-1:80, more preferably 8:1-1:40.
In a preferred embodiment of the present invention, described component A and the weight ratio of B component are more preferably 8:1-1:8, also can be more preferably 8:1-1:1.
In a preferred embodiment of the present invention, described component A and the weight ratio of B component can be preferably 1:1-1:40, also can be preferably 1:1-1:8 or 1:4-1:20.
Above-mentioned can also contain auxiliary agent and carrier containing 4-to the composition of the DOX compounds of phenoxy-phenoxy methyl structural.
Wherein, described auxiliary agent can be one or more in wetting agent, dispersant, emulsifier, suspending agent, antifreeze, binding agent, thickener, film forming agent, pH adjusting agent.
Described carrier can be selected from aluminium-magnesium silicate, organobentonite, aerosil, ammonium sulfate, diatomite, precipitated calcium carbonate, attapulgite, bentonite, kaolin, calcite, talcum, imvite, bentonite, white carbon, calcium carbonate, tripoli, soluble starch, corn starch, cellulose powder etc. one or more.
Pigment can also be comprised, as the component of one or more in mill base Red175, indigo, carmetta, iron oxide yellow, Dycoseed mill base etc. in described composition.
Described wetting agent is also known as bleeding agent, and Main Function is that solid material in composition is more easily soaked in water.In composition provided by the invention, wetting agent can select one or more in sodium butylnaphthalenesulfonate, lauryl sodium sulfate, neopelex, calcium dodecyl benzene sulfonate (agriculture breast 500#), styryl phenyl APEO (agriculture breast 601#) lignosulfonates, isopropyl naphthalene sulfonate, sodium alklyarylsulfonate, Morwet EFW etc.
Described dispersant is used to reduce solid or liquid particle in composition dispersion system to be assembled, add dispersant to be easy to form dispersion liquid and suspension when preparing wetting powder, water dispersible granules, aqueous dispersion tablets, suspending agent, oil suspending agent, and keep the metastable function of dispersion.In composition provided by the invention, dispersant can select phosphate, Sulfonates, alkylnaphthalene sulfonate condensation polymer, carboxylate macromolecule, polycarboxylate polymeric modified resin, alkyl sulfate, modified alkyl sulfonate, alkyl naphthalene sulfonic acid condensation polymer sodium salt, naphthalene sulfonate (condensation polymer) class, polycarboxylate polymeric dispersant, multi-styrene phenylate phosphate dispersant, naphthalenesulfonate formaldehyde condensation compound, alkylphenol polyoxyethylene, formaldehyde condensate sulfonate, lignosulfonates, maleic acid-acrylic acid copolymer sodium salt, one or more in alkyl sulfo succinate etc., as AtloxMetasperse550S, Dispersol BB4, Dispersol CBZ, Terwet1004, Tersperse2700, MorwetD-450, Borresperse CA-SA, sodium phosphate trimer, Nekal BX, YUS-TXC, YUS-FS1, TamolNN8906, dispersant NNO etc.
Described emulsifier to impel in composition two kinds of immiscible liquid to form stabilized emulsion, also can be the stabilizing agent of emulsion simultaneously.In composition provided by the invention, emulsifier can select calcium dodecyl benzene sulfonate, triphenoethyl benzene phenol polyethenoxy ether, alkyl phenol formaldehyde resin polyoxyethylene ether, fatty alcohol-polyoxyethylene ether, alkylphenol polyoxyethylene, castor oil polyoxyethylene ether, polyoxyethylene nonylphenol ether, OPEO, Fatty alcohol polyoxyethylene polyoxypropylene ether, fatty alcohol-polyoxyethylene ether modifier, aliphatic amine polyoxyethylene ether, alkylaryl polyoxyethylene poly-oxygen propylene aether, EO-PO block polyether, oleic acid polyoxyethylene, phenethyl phenol APEO, one or more in nonyl phenol phosphate etc., as YUS-110, YUS-EP60P, styrene-maleic anhydride copolymer sodium salt, SP-OF3404 etc.
Described suspending agent is used for increasing the viscosity of dispersion medium in composition to reduce settling velocity or the increase particulate hydrophily of particulate.In composition provided by the invention, suspending agent can select phosphate, Sulfonates, alkylnaphthalene sulfonate condensation polymer, carboxylate macromolecule, polycarboxylate polymeric modified resin, alkyl sulfate, modified alkyl sulfonate, alkyl naphthalene sulfonic acid condensation polymer sodium salt, naphthalene sulfonate (condensation polymer) class, polycarboxylate polymeric dispersant, multi-styrene phenylate phosphate dispersant, naphthalenesulfonate formaldehyde condensation compound, alkylphenol polyoxyethylene formaldehyde condensate sulfonate, lignosulfonates, white carbon, one or more in aluminium-magnesium silicate etc., as Tersperse2500, Tersperse4894, soybean oil, SP-3266 etc.
Described defoamer is for the production of removing too much foam in process.In composition provided by the invention, defoamer can select one or more in GP type defoamer, PE type defoamer, GPES type defoamer, SAG1522 type defoamer, organosilicon, polyether-modified silicon, polysiloxanes etc.
Described antifreeze is used to reduce the freezing point of composition liquid, improve the material of freezing tolerance.One or more in composition provided by the invention in the optional spent glycol of antifreeze, propane diols, butanols, glycerine, urea etc.
Described binding agent is used to homogeneity in composition or the bonding material linked together of heterogeneous body surface.In composition provided by the invention, binding agent can select one or more in sodium carboxymethylcellulose, polyvinylpyrrolidone, starch, polyvinyl alcohol, methylcellulose, fructose etc., as corn starch, cyclohexanone etc.
Described thickener is used to the viscosity of dispersion medium in increase composition to reduce the settling velocity of particulate, improves the layering of composition liquid.Composition thickener provided by the invention can select in xanthans, Macrogol 4000, Macrogol 6000, gum Arabic, gelatin, epoxy soybean wet goods one or more.
Described film forming agent is that active ingredient is sticked to the surface of the seed, forms smooth medicine film.Film forming agent in composition provided by the invention can select in polyvinyl alcohol, polyvinyl acetate, carboxymethyl cellulose, Arabic gelatin, gelatin, xanthans etc. one or more, as film forming agent BF308, Lauryl Alcohol ester, film forming agent CMJ-002-02 etc.
Described pH adjusting agent is used to the acid-base value regulating composition.In composition provided by the invention, pH adjusting agent can select one or more in citric acid, sodium bicarbonate, diethylamine, triisopropanolamine, phosphoric acid, glacial acetic acid.
The formulation of above-mentioned composition is any one in solution, emulsion, aqueous emulsion, missible oil, wetting powder, suspending agent, pulvis (powder agent), paste, soluble powder, granule, outstanding newborn concentrating agents, oil suspending agent, microcapsule formulations, seed treatment.And be preferably wetting powder, water dispersion granule, suspending agent, seed treatment, missible oil, microcapsule formulations, oil suspending agent, any one in aqueous emulsion, be more preferably dispersible in granula, wetting powder, suspending agent, oil suspending agent any one.
A second aspect of the present invention provides a kind of application of above-mentioned composition, can directly act on insect or act in its environment, habitat or storage areas.
Composition of the present invention can act in the environment of insect and/or pests live.
Composition of the present invention can be applied to one or more the process in the stem of plant, leaf, seed, fruit, root or soil, and wherein, the described process for seed, can use at least one deck dressing.
Preferably, the processing method of composition of the present invention can be flood, spray, evaporate, be atomized, broadcast sowing, one or more in brushing etc.
Wherein, described plant is preferably crops (comprising cereal, veterinary antibiotics etc.), gardening, fruit tree and dark woods plant, is preferably cereal, vegetable crop, as paddy rice, wheat, corn, Chinese cabbage etc.; Can be for field control insect, or in storage process pest control.Described insect can be rice-stem borer, rice leaf roller, Cucumber blight, cabbage aphid, cotten aphid, wheat aphid, black peach aphid, little green statin leafhopper, brown planthopper, small brown rice planthopper, white-backed planthopper, sweet potato whitefly, greenhouse whitefly, phyllocnistis citrella stainton, maize army worm, diamond-back moth, peanut grub, paddy rice thrips, cotton thrips etc.
Composition of the present invention can be used for the commercially available separately of process or is cultivating the plant of use.
The 4-that contains of the present invention is to 1 of phenoxy-phenoxy methyl structural, the drug effect of the complex preparation product of 3-dioxolane compound and amide-type insecticide is apparently higher than preventive effect when using single-dose product, thus greatly can reduce the resistance risk of insect, improve the service efficiency of composition, decrease dosage, thus reduce the use of composition pesticide to the impact of environment, and composition composite after have significant synergies, substantially increase the preventive effect to insect.
Specific embodiment
Below in conjunction with specific embodiment, the present invention will be further described, but not as limiting to the invention.
embodiment 1
Experimental technique: with reference to the related content in GB/T17980.2-2000 " agricultural chemicals field efficacy experiment criterion (one) insecticide control rice leaf roller ".
Experiment effect computational methods:
Control efficiency is converted into probability value (y), and liquor strength (μ g/ml) converts logarithm value to (x), calculates virulence equation and concentration EC50(half-maximal effect concentration in suppressing with method of least squares).
The method calculating the co-toxicity coefficient of built agent according to poison exponent calculates toxicity index and the co-toxicity coefficient (CTC) of medicament.
Theoretical toxicity index TTI=∑ (percentage of toxicity index TI × single dose in mixture of each single dose)
Experimental judgment foundation:
When CTC≤80, then composition shows as antagonism, works as 80<CTC<120, then composition shows as summation action, and when CTC >=120, then composition shows as synergistic effect.
By 4-to phenoxy group Phenoxymethyl-2-ethyl-1,3-dioxolanes and Tolfenpyrad are mixed to get multiple mixture according to the part by weight of 80:1-1:80, regularly choose multiple mixture determining its to the toxicity action of rice leaf roller, test result is as shown in table 1.
Table 1,4-of the present invention to phenoxy group Phenoxymethyl-2-ethyl-DOX and Tolfenpyrad composition pesticide to rice
The virulence test result of leaf-roller
Interpretation: as can be seen from Table 1:
1) 4-is to phenoxy group Phenoxymethyl-2-ethyl-DOX and Tolfenpyrad within the scope of the part by weight of 80:1-1:80, and actual measurement toxicity index (ATI) is all higher than toxicity index (TTI).Especially 4-is to phenoxy group Phenoxymethyl-2-ethyl-DOX and Tolfenpyrad within the scope of the part by weight of 8:1-1:4, and ATI is far above TTI, and actual measurement toxicity index (ATI) is about three times of toxicity index (TTI), illustrates that synergistic effect is obvious.
2) 4-is to phenoxy group Phenoxymethyl-2-ethyl-DOX and Tolfenpyrad within the scope of the part by weight of 80:1-1:80, and co-toxicity coefficient (CTC) is all greater than 80, there is not antagonism; 4-is to phenoxy group Phenoxymethyl-2-ethyl-1,3-dioxolanes and Tolfenpyrad are within the scope of the part by weight of 80:1-1:80, CTC is close to or higher than 120, especially 4-is to phenoxy group Phenoxymethyl-2-ethyl-1,3-dioxolanes and Tolfenpyrad are within the scope of the part by weight of 40:1-1:80, CTC, all higher than 120, has obvious synergistic effect; Wherein, 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX and Tolfenpyrad within the scope of the part by weight of 8:1-4:1, CTC is the highest, and synergistic effect is comparatively strong, when especially part by weight scope is 4:1, CTC reaches 361.99, and its synergistic effect is the strongest.
3) 4-is to phenoxy group Phenoxymethyl-2-ethyl-DOX and Tolfenpyrad within the scope of the part by weight of 80:1-1:80, and actual measurement toxicity index (ATI) is all higher than the toxicity index 114.81 of Tolfenpyrad.
4) 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX and Tolfenpyrad within the scope of the part by weight of 80:1-4:1, along with the increase of Tolfenpyrad ratio, to the median lethal concentration (LC of rice leaf roller
50) decline, but within the scope of the part by weight of 4:1-1:80, along with the increase of the ratio of Tolfenpyrad, to the median lethal concentration (LC of rice leaf roller
50) rise.4-is to phenoxy group Phenoxymethyl-2-ethyl-DOX and Tolfenpyrad within the scope of the part by weight of 8:1-1:1, and 4-is to the LC of phenoxy group Phenoxymethyl-2-ethyl-DOX and Tolfenpyrad complex composition
50far below being used alone 4-to LC during phenoxy group Phenoxymethyl-2-ethyl-DOX
50, 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX and Tolfenpyrad within the scope of the part by weight of 8:2-1:1, the LC of composition
50be starkly lower than the LC of Tolfenpyrad
50.
Can find out, 4-provided by the invention is to phenoxy group Phenoxymethyl-2-ethyl-1,3-dioxolanes and Tolfenpyrad composition, when 4-is to phenoxy group Phenoxymethyl-2-ethyl-1,3-dioxolanes and Tolfenpyrad are within the scope of the part by weight of 80:1-1:80, there is not antagonism, and can LC be reduced
50; 4-is to phenoxy group Phenoxymethyl-2-ethyl-1,3-dioxolanes and Tolfenpyrad are within the scope of the part by weight of 40:1-1:80, there is synergistic effect, 4-is to phenoxy group Phenoxymethyl-2-ethyl-1,3-dioxolanes and Tolfenpyrad are within the scope of the part by weight of 8:1-1:1, and synergistic effect is the most obvious; 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX and Tolfenpyrad within the scope of the part by weight of 8:1-1:1, the LC of composition
50very low, safety in utilization obtains and improves.
Comprehensively above-mentioned various factors, when the part by weight of 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX and Tolfenpyrad is 8:1-1:1, has optimum efficiency.
embodiment 2
Experimental technique: with reference to the related content in GB/T17980.2-2000 " agricultural chemicals field efficacy experiment criterion (one) insecticide control striped rice borer ".
Experiment effect computational methods and experimental judgment foundation: identical with embodiment 1.
4-is mixed to get multiple mixture to phenoxy group Phenoxymethyl-2-ethyl-DOX and Tolfenpyrad according to the part by weight of 80:1-1:80, choose wherein several mixture determining its to the toxicity action of striped rice borer.
Experimental result: as shown in table 2.
Table 2,4-of the present invention to phenoxy group Phenoxymethyl-2-ethyl-DOX and Tolfenpyrad composition pesticide to two
Change the virulence test result of snout moth's larva
Interpretation: as can be seen from Table 2:
1) 4-is to phenoxy group Phenoxymethyl-2-ethyl-DOX and Tolfenpyrad within the scope of the part by weight of 80:1-1:80, and actual measurement toxicity index (ATI) is all higher than toxicity index (TTI).Especially 4-is to phenoxy group Phenoxymethyl-2-ethyl-1,3-dioxolanes and Tolfenpyrad within the scope of the part by weight of 20:1-1:8, ATI far above TTI, within the scope of this, actual measurement toxicity index (ATI) is about the twice of toxicity index (TTI), illustrates that synergistic effect is obvious.
2) 4-is to phenoxy group Phenoxymethyl-2-ethyl-DOX and Tolfenpyrad within the scope of the part by weight of 80:1-1:80, and co-toxicity coefficient (CTC) is all greater than 120, has synergistic effect; Wherein, the part by weight of 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX and Tolfenpyrad is within the scope of the part by weight of 8:1-1:8, co-toxicity coefficient (CTC) all close to or be greater than 200, CTC and reach as high as 270.17, its synergistic effect is the strongest.
3) 4-is to phenoxy group Phenoxymethyl-2-ethyl-DOX and Tolfenpyrad within the scope of the part by weight of 80:1-1:80, and actual measurement toxicity index (ATI) is all higher than the toxicity index 115.06 of Tolfenpyrad.
4) 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX and Tolfenpyrad within the scope of the part by weight of 80:1-1:20, along with the increase of Tolfenpyrad ratio, to the median lethal concentration (LC of striped rice borer
50) decline obviously, but when Tolfenpyrad ratio is excessive, be 1:20-1:80, LC as worked as the part by weight scope of 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX and Tolfenpyrad
50there is the trend slightly risen; 4-is to phenoxy group Phenoxymethyl-2-ethyl-DOX and Tolfenpyrad within the scope of the part by weight of 80:1-1:80, and 4-is to the LC of phenoxy group Phenoxymethyl-2-ethyl-DOX and Tolfenpyrad complex composition
50all lower than being used alone 4-to LC when phenoxy group Phenoxymethyl-2-ethyl-DOX and Tolfenpyrad
50.
Can find out, 4-provided by the invention is to phenoxy group Phenoxymethyl-2-ethyl-DOX and Tolfenpyrad composition, and 4-is to phenoxy group Phenoxymethyl-2-ethyl-1,3-dioxolanes and Tolfenpyrad, within the scope of the part by weight of 80:1-1:80, have synergistic effect.And can LC be reduced
50, 4-is to phenoxy group Phenoxymethyl-2-ethyl-DOX and Tolfenpyrad within the scope of the part by weight of 8:1-1:8, and synergistic effect is the most obvious; 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX and Tolfenpyrad within the scope of the part by weight of 8:1-1:8, the LC of composition
50very low, the safety of use obtains and improves.
Comprehensively above-mentioned various factors, when the part by weight of 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX and Tolfenpyrad is 8:1-1:8, has optimum efficiency.
embodiment 3
Experimental technique: with reference to the related content in GB/T17980-2000 " agricultural chemicals field efficacy experiment criterion () ".
Experiment effect computational methods and experimental judgment foundation: identical with embodiment 1.
4-is mixed to get multiple mixture to phenoxy group Phenoxymethyl-2-ethyl-DOX and Tolfenpyrad according to the part by weight of 80:1-1:80, chooses wherein several mixture and measure its toxicity action to diamond-back moth.
Experimental result: as shown in table 3.
Table 3,4-of the present invention is to phenoxy group Phenoxymethyl-2-ethyl-DOX and Tolfenpyrad composition pesticide
To the virulence test result of diamond-back moth
Interpretation: as can be seen from Table 3:
1) 4-is to phenoxy group Phenoxymethyl-2-ethyl-DOX and Tolfenpyrad within the scope of the part by weight of 80:1-1:80, and actual measurement toxicity index (ATI) is all higher than the toxicity index (ATI) of Tolfenpyrad.
2) 4-is to phenoxy group Phenoxymethyl-2-ethyl-DOX and Tolfenpyrad within the scope of the part by weight of 80:1-1:80, and actual measurement toxicity index (ATI) is all higher than toxicity index (TTI).
3) 4-is to phenoxy group Phenoxymethyl-2-ethyl-DOX and Tolfenpyrad within the scope of the part by weight of 80:1-1:80, and co-toxicity coefficient (CTC) is all close to or higher than 120, has synergistic effect; 4-is to phenoxy group Phenoxymethyl-2-ethyl-DOX and Tolfenpyrad within the scope of the part by weight of 20:1-1:80, and co-toxicity coefficient (CTC), all higher than 120, has obvious synergistic effect; Wherein, 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX and Tolfenpyrad at 8:1-1:1(especially 4:1) part by weight within the scope of, CTC reaches as high as 176.91, and its synergistic effect is obvious.
4) 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX and Tolfenpyrad within the scope of the part by weight of 80:1-1:80, along with the increase of Tolfenpyrad ratio, to the median lethal concentration (LC of diamond-back moth
50) decline obviously, but when Tolfenpyrad ratio is excessive, be 1:4-1:80, LC as worked as the part by weight of 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX and Tolfenpyrad
50there is ascendant trend slightly; When 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX and Tolfenpyrad within the scope of the part by weight of 80:1-1:80,4-is to the LC of phenoxy group Phenoxymethyl-2-ethyl-DOX and Tolfenpyrad complex composition
50lower than being used alone 4-to LC when phenoxy group Phenoxymethyl-2-ethyl-DOX or Tolfenpyrad
50.
Can find out, 4-provided by the invention is to phenoxy group Phenoxymethyl-2-ethyl-1,3-dioxolanes and Tolfenpyrad composition, when 4-is to phenoxy group Phenoxymethyl-2-ethyl-1,3-dioxolanes and Tolfenpyrad are within the scope of the part by weight of 80:1-1:80, there is not antagonism, and can LC be reduced
50; 4-is to phenoxy group Phenoxymethyl-2-ethyl-1,3-dioxolanes and Tolfenpyrad are within the scope of the part by weight of 40:1-1:80, there is synergistic effect, 4-is to phenoxy group Phenoxymethyl-2-ethyl-1,3-dioxolanes and Tolfenpyrad are within the scope of the part by weight of 8:1-1:4, and synergistic effect is the most obvious; 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX and Tolfenpyrad within the scope of the part by weight of 20:1-1:8, the LC of composition
50very low, safety in utilization obtains and improves.
Comprehensively above-mentioned various factors, when 4-is to phenoxy group Phenoxymethyl-2-ethyl-DOX and Tolfenpyrad 8:1-1:8, has optimum efficiency.
embodiment 4
Experimental technique: with reference to the related content in GB/T17980.2-2000 " agricultural chemicals field efficacy experiment criterion (one) insecticide control rice leaf roller ".
Experiment effect computational methods and experimental judgment foundation: identical with embodiment 1.
4-is mixed to get multiple mixture to phenoxy group Phenoxymethyl-2-ethyl-DOX and Rynaxypyr according to the part by weight of 80:1-1:80, choose wherein several mixture determining its to the toxicity action of rice leaf roller.
Experimental result: as shown in table 4.
Table 4,4-of the present invention is to phenoxy group Phenoxymethyl-2-ethyl-DOX and chlorantraniliprole pesticide composition
To the virulence test result of rice leaf roller
Interpretation: as can be seen from Table 4:
1) 4-is to phenoxy group Phenoxymethyl-2-ethyl-DOX and Rynaxypyr within the scope of the part by weight of 1:4-1:80, and actual measurement toxicity index (ATI) is all higher than the toxicity index of Rynaxypyr.
2) 4-is to phenoxy group Phenoxymethyl-2-ethyl-DOX and Rynaxypyr within the scope of the part by weight of 80:1-1:80, and actual measurement toxicity index (ATI) is all higher than toxicity index (TTI).Especially 4-is to phenoxy group Phenoxymethyl-2-ethyl-1,3-dioxolanes and Rynaxypyr within the scope of the part by weight of 1:1-1:8, ATI higher than TTI, within the scope of this, actual measurement toxicity index (ATI) is close to or higher than the twice of toxicity index (TTI), illustrates that synergistic effect is obvious.
3) 4-is to phenoxy group Phenoxymethyl-2-ethyl-1,3-dioxolanes and Rynaxypyr are within the scope of the part by weight of 80:1-1:80, co-toxicity coefficient (CTC) is all greater than 120, there is obvious synergistic effect, wherein, 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX and Rynaxypyr at 1:1-1:20(especially 1:4) part by weight within the scope of, CTC reaches as high as 207.58, and synergistic effect is obvious.
4) 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX and Rynaxypyr within the scope of the part by weight of 80:1-1:80, along with the increase of Rynaxypyr ratio, to the median lethal concentration (LC of rice leaf roller
50) decline, but when Rynaxypyr ratio is excessive, be 1:40-1:80, LC as worked as the part by weight scope of 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX and Rynaxypyr
50there is ascendant trend a little; When 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX and Rynaxypyr within the scope of the part by weight of 80:1-1:80,4-is to the LC of phenoxy group Phenoxymethyl-2-ethyl-DOX and Rynaxypyr complex composition
50far below being used alone 4-to LC during phenoxy group Phenoxymethyl-2-ethyl-DOX
50; Especially when 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX and Rynaxypyr within the scope of the part by weight of 1:4-1:80, with LC when being used alone Rynaxypyr element
50lower.
Can find out, 4-provided by the invention is to phenoxy group Phenoxymethyl-2-ethyl-1,3-dioxolanes and Rynaxypyr composition, when 4-is to phenoxy group Phenoxymethyl-2-ethyl-1,3-dioxolanes and Rynaxypyr, within the scope of the part by weight of 80:1-1:80, have synergistic effect, and 4-is to phenoxy group Phenoxymethyl-2-ethyl-1,3-dioxolanes and Rynaxypyr are within the scope of the part by weight of 1:1-1:40, and synergistic effect is the most obvious; 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX and Rynaxypyr within the scope of the part by weight of 1:1-1:80, the LC of composition
50very low, safety in utilization obtains and improves.
Comprehensively above-mentioned various factors, when the part by weight of 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX and Rynaxypyr is 1:1-1:40, has optimum efficiency.
embodiment 5
Experimental technique: with reference to the related content in GB/T17980-2000 " agricultural chemicals field efficacy experiment criterion () ".
Experiment effect computational methods and experimental judgment foundation: identical with embodiment 1.
4-is mixed to get multiple mixture to phenoxy group Phenoxymethyl-2-ethyl-DOX and Rynaxypyr according to the part by weight of 80:1-1:80, choose wherein several mixture determining its to the toxicity action of striped rice borer.
Experimental result: as shown in table 5.
Table 5,4-of the present invention is to phenoxy group Phenoxymethyl-2-ethyl-DOX and chlorantraniliprole pesticide composition
To the virulence test result of striped rice borer
Interpretation: as can be seen from Table 5:
1) 4-is to phenoxy group Phenoxymethyl-2-ethyl-DOX and Rynaxypyr within the scope of the part by weight of 80:1-1:80, and actual measurement toxicity index (ATI) is all higher than toxicity index (TTI).
2) 4-is to phenoxy group Phenoxymethyl-2-ethyl-1,3-dioxolanes and Rynaxypyr are within the scope of the part by weight of 80:1-1:80, co-toxicity coefficient (CTC) is all apparently higher than 120, especially 4-is to phenoxy group Phenoxymethyl-2-ethyl-DOX and Rynaxypyr within the scope of the part by weight of 4:1-1:8, and CTC is all greater than 170, synergistic effect is stronger, especially when part by weight scope is 1:4, CTC reaches 217.71, and synergistic effect is the strongest.
3) 4-is to phenoxy group Phenoxymethyl-2-ethyl-DOX and Rynaxypyr within the scope of the part by weight of 1:1-1:80, and actual measurement toxicity index (ATI) is all higher than the toxicity index 980.32 of Rynaxypyr.
4) 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX and Rynaxypyr within the scope of the part by weight of 80:1-1:4, along with the increase of Rynaxypyr ratio, to the median lethal concentration (LC of striped rice borer
50) decline obviously, when the part by weight scope of 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX and Rynaxypyr is 1:1-1:80, LC
50for 3.54-5.21, lower than the LC being used alone Rynaxypyr
506.25; And 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX and Rynaxypyr within the scope of the part by weight of 80:1-1:80,4-is to the LC of phenoxy group Phenoxymethyl-2-ethyl-DOX and Rynaxypyr complex composition
50far below being used alone 4-to LC during phenoxy group Phenoxymethyl-2-ethyl-DOX
5061.27.
Can find out, 4-provided by the invention is to phenoxy group Phenoxymethyl-2-ethyl-1, the composition of 3-dioxolanes and Rynaxypyr, when 4-is to phenoxy group Phenoxymethyl-2-ethyl-1,3-dioxolanes and Rynaxypyr are within the scope of the part by weight of 80:1-1:80, there is synergistic effect, and can reduce and be used alone the LC of 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX or Rynaxypyr
50; , 4-is to phenoxy group Phenoxymethyl-2-ethyl-DOX and Rynaxypyr within the scope of the part by weight of 4:1-1:8, and synergistic effect is the most obvious; 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX and Rynaxypyr within the scope of the part by weight of 1:1-1:80, the LC of composition
50very low, safety in utilization obtains and improves.
Comprehensively above-mentioned various factors, when the part by weight of 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX and Rynaxypyr is 1:1-1:8, has optimum efficiency.
embodiment 6
Experimental technique: with reference to the related content in GB/T17980-2000 " agricultural chemicals field efficacy experiment criterion () ".
Experiment effect computational methods and experimental judgment foundation: identical with embodiment 1.
4-is mixed to get multiple mixture to phenoxy group Phenoxymethyl-2-ethyl-DOX and Rynaxypyr according to the part by weight of 80:1-1:80, choose wherein several mixture determining its to the toxicity action of paddy stem borer.
Experimental result: as shown in table 6.
Table 6,4-of the present invention is to phenoxy group Phenoxymethyl-2-ethyl-DOX and chlorantraniliprole pesticide composition
To the virulence test result of paddy stem borer
Interpretation: as can be seen from Table 6:
1) 4-is to phenoxy group Phenoxymethyl-2-ethyl-DOX and Rynaxypyr within the scope of the part by weight of 80:1-1:80, and actual measurement toxicity index (ATI) is all higher than toxicity index (TTI).
2) 4-is to phenoxy group Phenoxymethyl-2-ethyl-1,3-dioxolanes and Rynaxypyr are within the scope of the part by weight of 80:1-1:80, co-toxicity coefficient (CTC) is all close to or higher than 120, especially 4-is to phenoxy group Phenoxymethyl-2-ethyl-DOX and Rynaxypyr within the scope of the part by weight of 40:1-1:8, and CTC is greater than 147, synergistic effect is stronger, especially when part by weight scope is 1:1, CTC reaches 192.05, and synergistic effect is the strongest.
3) 4-is to phenoxy group Phenoxymethyl-2-ethyl-DOX and Rynaxypyr within the scope of the part by weight of 1:1-1:80, and actual measurement toxicity index (ATI) is all higher than the toxicity index 829.88 of Rynaxypyr.
4) 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX and Rynaxypyr within the scope of the part by weight of 80:1-1:4, along with the increase of Rynaxypyr ratio, to the median lethal concentration (LC of paddy stem borer
50) decline obviously, when the part by weight scope of 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX and Rynaxypyr is 1:1-1:80, LC
50for 3.05-3.95, lower than the LC being used alone Rynaxypyr
504.25; And 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX and Rynaxypyr within the scope of the part by weight of 80:1-1:80,4-is to the LC of phenoxy group Phenoxymethyl-2-ethyl-DOX and Rynaxypyr complex composition
50far below being used alone 4-to LC during phenoxy group Phenoxymethyl-2-ethyl-DOX
5035.27.
Can find out, 4-provided by the invention is to phenoxy group Phenoxymethyl-2-ethyl-1, the composition of 3-dioxolanes and Rynaxypyr, when 4-is to phenoxy group Phenoxymethyl-2-ethyl-1,3-dioxolanes and Rynaxypyr are within the scope of the part by weight of 80:1-1:40, there is synergistic effect, and can reduce and be used alone the LC of 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX or Rynaxypyr
50; , 4-is to phenoxy group Phenoxymethyl-2-ethyl-DOX and Rynaxypyr within the scope of the part by weight of 40:1-1:8, and synergistic effect is the most obvious; 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX and Rynaxypyr within the scope of the part by weight of 1:1-1:80, the LC of composition
50very low, safety in utilization obtains and improves.
Comprehensively above-mentioned various factors, when the part by weight of 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX and Rynaxypyr is 1:1-1:8, has optimum efficiency.
embodiment 7
Experimental technique: with reference to the related content in GB/T17980.80-2004 " pesticide field efficacy medicine test criterion (two) the 80th part: insecticide control mythimna separata ".
Experiment effect computational methods and experimental judgment foundation: identical with embodiment 1.
4-is mixed to get multiple mixture to phenoxy group Phenoxymethyl-2-ethyl-DOX and Rynaxypyr according to the part by weight of 80:1-1:80, choose wherein several mixture determining its to the toxicity action of mythimna separata.
Experimental result: as shown in table 7.
Table 7,4-of the present invention is to phenoxy group Phenoxymethyl-2-ethyl-DOX and chlorantraniliprole pesticide composition
To the virulence test result of mythimna separata
Interpretation: as can be seen from Table 7:
1) 4-is to phenoxy group Phenoxymethyl-2-ethyl-DOX and Rynaxypyr within the scope of the part by weight of 80:1-1:80, and actual measurement toxicity index (ATI) is all higher than toxicity index (TTI).
2) 4-is to phenoxy group Phenoxymethyl-2-ethyl-1,3-dioxolanes and Rynaxypyr are within the scope of the part by weight of 80:1-1:80, co-toxicity coefficient (CTC) is all close to or higher than 120, especially 4-is to phenoxy group Phenoxymethyl-2-ethyl-DOX and Rynaxypyr within the scope of the part by weight of 8:1-1:20, and its CTC is all greater than 160, synergistic effect is stronger, especially when part by weight scope is 1:4, CTC reaches 224.54, and synergistic effect is the strongest.
3) 4-is to phenoxy group Phenoxymethyl-2-ethyl-DOX and Rynaxypyr within the scope of the part by weight of 1:4-1:80, and actual measurement toxicity index (ATI) is all higher than the toxicity index 1003.42 of Rynaxypyr.
4) 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX and Rynaxypyr within the scope of the part by weight of 80:1-1:4, along with the increase of Rynaxypyr ratio, to the median lethal concentration (LC of mythimna separata
50) decline obviously, when the part by weight scope of 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX and Rynaxypyr is 1:4-1:80, LC
50for 3.65-5.72, lower than the LC being used alone Rynaxypyr
506.72; And 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX and Rynaxypyr within the scope of the part by weight of 80:1-1:80,4-is to the LC of phenoxy group Phenoxymethyl-2-ethyl-DOX and Rynaxypyr complex composition
50far below being used alone 4-to LC during phenoxy group Phenoxymethyl-2-ethyl-DOX
5067.43.
Can find out, 4-provided by the invention is to phenoxy group Phenoxymethyl-2-ethyl-1, the composition of 3-dioxolanes and Rynaxypyr, when 4-is to phenoxy group Phenoxymethyl-2-ethyl-1,3-dioxolanes and Rynaxypyr are within the scope of the part by weight of 80:1-1:80, there is synergistic effect, and can reduce and be used alone the LC of 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX or Rynaxypyr
50; , 4-is to phenoxy group Phenoxymethyl-2-ethyl-DOX and Rynaxypyr within the scope of the part by weight of 8:1-1:20, and synergistic effect is the most obvious; 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX and Rynaxypyr within the scope of the part by weight of 1:4-1:80, the LC of composition
50very low, safety in utilization obtains and improves.
Comprehensively above-mentioned various factors, when the part by weight of 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX and Rynaxypyr is 1:4-1:20, has optimum efficiency.
embodiment 8
Experimental technique: with reference to the related content in GB/T17980.2-2000 " agricultural chemicals field efficacy experiment criterion (one) insecticide control rice leaf roller ".
Experiment effect computational methods and experimental judgment foundation: identical with embodiment 1.
4-is mixed to get multiple mixture to phenoxy group Phenoxymethyl-2-ethyl-DOX and fipronil bisamide according to the part by weight of 80:1-1:80, choose wherein several mixture determining its to the toxicity action of rice leaf roller.
Experimental result: as shown in table 8.
Table 8,4-of the present invention is to phenoxy group Phenoxymethyl-2-ethyl-DOX and fipronil bisamide composition pesticide pair
The virulence test result of rice leaf roller
Interpretation: as can be seen from Table 8:
1) 4-is to phenoxy group Phenoxymethyl-2-ethyl-DOX and fipronil bisamide within the scope of the part by weight of 80:1-1:80, and actual measurement toxicity index (ATI) is all higher than toxicity index (TTI).
2) 4-is to phenoxy group Phenoxymethyl-2-ethyl-1,3-dioxolanes and fipronil bisamide are within the scope of the part by weight of 80:1-1:80, co-toxicity coefficient (CTC) is all close to or higher than 120, especially 4-is to phenoxy group Phenoxymethyl-2-ethyl-DOX and fipronil bisamide within the scope of the part by weight of 20:1-1:20, and its CTC is all greater than 150, synergistic effect is stronger, especially when part by weight is 1:8, CTC reaches 180.16, and synergistic effect is the strongest.
3) 4-is to phenoxy group Phenoxymethyl-2-ethyl-DOX and fipronil bisamide within the scope of the part by weight of 1:4-1:80, and actual measurement toxicity index (ATI) is all higher than the toxicity index 642.72 of fipronil bisamide.
4) 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX and fipronil bisamide within the scope of the part by weight of 80:1-1:8, along with the increase of fipronil bisamide ratio, to the median lethal concentration (LC of rice leaf roller
50) decline obviously, when the part by weight scope of 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX and fipronil bisamide is 1:4-1:80, LC
50for 5.09-7.01, lower than the LC being used alone fipronil bisamide
508.31; And 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX and fipronil bisamide within the scope of the part by weight of 80:1-1:80,4-is to the LC of phenoxy group Phenoxymethyl-2-ethyl-DOX and fipronil bisamide complex composition
50far below being used alone 4-to LC during phenoxy group Phenoxymethyl-2-ethyl-DOX
5053.41.
Can find out, 4-provided by the invention is to phenoxy group Phenoxymethyl-2-ethyl-1, the composition of 3-dioxolanes and fipronil bisamide, when 4-is to phenoxy group Phenoxymethyl-2-ethyl-1,3-dioxolanes and fipronil bisamide are within the scope of the part by weight of 80:1-1:40, there is synergistic effect, and can reduce and be used alone the LC of 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX or fipronil bisamide
50; , 4-is to phenoxy group Phenoxymethyl-2-ethyl-DOX and fipronil bisamide within the scope of the part by weight of 20:1-1:20, and synergistic effect is the most obvious; 4-is to phenoxy group Phenoxymethyl-2-ethyl-DOX and fluorine
Interpretation: as can be seen from Table 9:
1) 4-is to phenoxy group Phenoxymethyl-2-ethyl-DOX and fipronil bisamide within the scope of the part by weight of 80:1-1:80, and actual measurement toxicity index (ATI) is all higher than toxicity index (TTI).
2) 4-is to phenoxy group Phenoxymethyl-2-ethyl-1,3-dioxolanes and fipronil bisamide are within the scope of the part by weight of 80:1-1:80, co-toxicity coefficient (CTC) is all higher than 120, especially 4-is to phenoxy group Phenoxymethyl-2-ethyl-DOX and fipronil bisamide within the scope of the part by weight of 1:4-1:20, and its CTC is all greater than 166, synergistic effect is stronger, especially when part by weight is 1:4, CTC reaches 204.06, and synergistic effect is the strongest.
3) 4-is to phenoxy group Phenoxymethyl-2-ethyl-DOX and fipronil bisamide within the scope of the part by weight of 1:4-1:80, and actual measurement toxicity index (ATI) is all higher than the toxicity index 900.00 of fipronil bisamide.
4) 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX and fipronil bisamide within the scope of the part by weight of 80:1-1:4, along with the increase of fipronil bisamide ratio, to the median lethal concentration (LC of diamond-back moth
50) decline obviously, when the part by weight scope of 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX and fipronil bisamide is 1:4-1:80, LC
50for 2.52-3.11, lower than the LC being used alone fipronil bisamide
504.01; And 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX and fipronil bisamide within the scope of the part by weight of 80:1-1:80,4-is to the LC of phenoxy group Phenoxymethyl-2-ethyl-DOX and fipronil bisamide complex composition
50far below being used alone 4-to LC during phenoxy group Phenoxymethyl-2-ethyl-DOX
5036.09.
Can find out, 4-provided by the invention is to phenoxy group Phenoxymethyl-2-ethyl-1, the composition of 3-dioxolanes and fipronil bisamide, when 4-is to phenoxy group Phenoxymethyl-2-ethyl-1,3-dioxolanes and fipronil bisamide are within the scope of the part by weight of 80:1-1:80, there is synergistic effect, and can reduce and be used alone the LC of 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX or fipronil bisamide
50; , 4-is to phenoxy group Phenoxymethyl-2-ethyl-DOX and fipronil bisamide within the scope of the part by weight of 1:4-1:20, and synergistic effect is the most obvious; 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX and fipronil bisamide within the scope of the part by weight of 1:4-1:80, the LC of composition
50very low, safety in utilization obtains and improves.
Comprehensively above-mentioned various factors, when the part by weight of 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX and fipronil bisamide is 1:4-1:20, has optimum efficiency.
embodiment 10
Experimental technique: with reference to the related content in GB/T17980.2-2000 " agricultural chemicals field efficacy experiment criterion (one) insecticide control rice leaf roller ".
Experiment effect computational methods and experimental judgment foundation: identical with embodiment 1.
4-is mixed to get multiple mixture to phenoxy group Phenoxymethyl-2-ethyl-DOX and bromine cyanogen insect amide according to the part by weight of 80:1-1:80, choose wherein several mixture determining its to rice leaf roller toxicity action.
Experimental result: as shown in table 10.
Table 10,4-of the present invention is to phenoxy group Phenoxymethyl-2-ethyl-DOX and bromine cyanogen insect amide composition pesticide pair
The virulence test result of rice leaf roller
Interpretation: as can be seen from Table 10:
1) 4-is to phenoxy group Phenoxymethyl-2-ethyl-DOX and bromine cyanogen insect amide within the scope of the part by weight of 80:1-1:80, and actual measurement toxicity index (ATI) is all higher than toxicity index (TTI).
2) 4-is to phenoxy group Phenoxymethyl-2-ethyl-1,3-dioxolanes and bromine cyanogen insect amide are within the scope of the part by weight of 80:1-1:80, co-toxicity coefficient (CTC) is all higher than 120, especially 4-is to phenoxy group Phenoxymethyl-2-ethyl-DOX and bromine cyanogen insect amide within the scope of the part by weight of 8:1-1:8, and its CTC is all greater than 180, synergistic effect is stronger, especially when part by weight is 1:1, CTC reaches 276.93, and synergistic effect is the strongest.
3) 4-is to phenoxy group Phenoxymethyl-2-ethyl-DOX and bromine cyanogen insect amide within the scope of the part by weight of 1:1-1:80, and actual measurement toxicity index (ATI) is all higher than the toxicity index 1061.83 of bromine cyanogen insect amide.
4) 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX and bromine cyanogen insect amide within the scope of the part by weight of 80:1-1:8, along with the increase of bromine cyanogen insect amide ratio, to the median lethal concentration (LC of rice leaf roller
50) decline obviously, when the part by weight scope of 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX and bromine cyanogen insect amide is 1:1-1:80, LC
50for 2.97-4.12, lower than the LC being used alone bromine cyanogen insect amide
505.03; And 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX and bromine cyanogen insect amide within the scope of the part by weight of 80:1-1:80,4-is to the LC of phenoxy group Phenoxymethyl-2-ethyl-DOX and bromine cyanogen insect amide complex composition
50far below being used alone 4-to LC during phenoxy group Phenoxymethyl-2-ethyl-DOX
5053.41.
Can find out, 4-provided by the invention is to phenoxy group Phenoxymethyl-2-ethyl-1, the composition of 3-dioxolanes and bromine cyanogen insect amide, when 4-is to phenoxy group Phenoxymethyl-2-ethyl-1,3-dioxolanes and bromine cyanogen insect amide are within the scope of the part by weight of 80:1-1:80, there is synergistic effect, and can reduce and be used alone the LC of 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX or bromine cyanogen insect amide
50; , 4-is to phenoxy group Phenoxymethyl-2-ethyl-DOX and bromine cyanogen insect amide within the scope of the part by weight of 8:1-1:8, and synergistic effect is the most obvious; 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX and bromine cyanogen insect amide within the scope of the part by weight of 1:1-1:80, the LC of composition
50very low, safety in utilization obtains and improves.
Comprehensively above-mentioned various factors, when the part by weight of 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX and bromine cyanogen insect amide is 1:1-1:8, has best preventive effect to rice leaf roller.
embodiment 11
Experimental technique: with reference to the related content in GB/T17980.2-2000 " agricultural chemicals field efficacy experiment criterion (one) insecticide control Cucumber blight ".
Experiment effect computational methods and experimental judgment foundation: identical with embodiment 1.
4-is mixed to get multiple mixture to phenoxy group Phenoxymethyl-2-ethyl-DOX and flonicamid according to the part by weight of 80:1-1:80, choose wherein several mixture determining its to Cucumber blight toxicity action.
Experimental result: as shown in table 11.
Table 11,4-of the present invention is to phenoxy group Phenoxymethyl-2-ethyl-DOX and flonicamid composition pesticide
The virulence test result of Cucumber blight
Interpretation: as can be seen from Table 11:
1) 4-is to phenoxy group Phenoxymethyl-2-ethyl-DOX and flonicamid within the scope of the part by weight of 80:1-1:80, and actual measurement toxicity index (ATI) is all higher than toxicity index (TTI).
2) 4-is to phenoxy group Phenoxymethyl-2-ethyl-1,3-dioxolanes and flonicamid are within the scope of the part by weight of 80:1-1:80, co-toxicity coefficient (CTC) is all higher than 120, especially 4-is to phenoxy group Phenoxymethyl-2-ethyl-DOX and flonicamid within the scope of the part by weight of 40:1-1:8, and its CTC is all greater than 176, synergistic effect is stronger, especially when part by weight is 40:1, CTC reaches 2418.49, and synergistic effect is the strongest.
3) 4-is to phenoxy group Phenoxymethyl-2-ethyl-DOX and flonicamid under the part by weight of 40:1, and actual measurement toxicity index (ATI) is 3985.84, and the TTI of correspondence is only about 24 times that 123.46, ATI are TTI.
4) 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX and flonicamid within the scope of the part by weight of 80:1-1:8, along with the increase of flonicamid ratio, to the median lethal concentration (LC of Cucumber blight
50) decline obviously, when 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX and flonicamid within the scope of the part by weight of 80:1-1:80,4-is to the LC of phenoxy group Phenoxymethyl-2-ethyl-DOX and flonicamid complex composition
50far below being used alone 4-to LC during phenoxy group Phenoxymethyl-2-ethyl-DOX
5065.39; When 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX and flonicamid within the scope of the part by weight of 80:1-1:80, LC
50all be greater than the LC being used alone flonicamid
500.78.
Can find out, 4-provided by the invention is to phenoxy group Phenoxymethyl-2-ethyl-1, the composition of 3-dioxolanes and flonicamid, when 4-is to phenoxy group Phenoxymethyl-2-ethyl-1,3-dioxolanes and flonicamid are within the scope of the part by weight of 80:1-1:80, there is synergistic effect, and can reduce and be used alone the LC of 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX or flonicamid
50; , 4-is to phenoxy group Phenoxymethyl-2-ethyl-DOX and flonicamid within the scope of the part by weight of 40:1-1:40, and synergistic effect is the most obvious; 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX and flonicamid within the scope of the part by weight of 40:1 or (1:1)-(1:80), the LC of composition
50very low, safety in utilization obtains and improves.
Comprehensively above-mentioned various factors, when the part by weight of 4-to phenoxy group Phenoxymethyl-2-ethyl-DOX and flonicamid is 40:1 or 1:1-1:40, has preferably preventive effect to Cucumber blight.
Embodiment 12, preparation formulation is the composition pesticide of wetting powder
The active constituent content preparing composition pesticide be the 4-of 25% to the Wettable pesticide powder composition of phenoxy group Phenoxymethyl-2-ethyl-DOX and Tolfenpyrad, with the gross weight of composition pesticide for benchmark, comprise following component:
Said components mixed, obtaining required active constituent content is that the 4-of 25% is to the Wettable pesticide powder composition of phenoxy group Phenoxymethyl-2-ethyl-DOX and Tolfenpyrad.
Embodiment 13, preparation formulation is the composition pesticide dispersibling granula
(1) active constituent content preparing composition pesticide be 60% 4-granule pesticide composition is dispersibled to phenoxy group Phenoxymethyl-2-ethyl-DOX and Tolfenpyrad, with the gross weight of composition pesticide for benchmark, comprise following component:
Said components is mixed, obtain required active constituent content be 60% 4-granule pesticide composition is dispersibled to phenoxy group Phenoxymethyl-2-ethyl-DOX and Tolfenpyrad.
Composition pesticide described in the embodiment of the present invention is for preventing and treating the test of pesticide effectiveness of paddy rice rice leaf roller.
Experimental technique: as described in above-described embodiment.
Experimental result: as shown in Table 12.
Table 12, the composition described in the present embodiment and 20%4-to phenoxy group Phenoxymethyl-2-ethyl-DOX (EC),
15% Tolfenpyrad (EC) is to the field control effectiveness test table of comparisons of rice leaf roller
Interpretation:
As can be seen from Table 12, in above-mentioned experiment, the using dosage of the composition pesticide described in the embodiment of the present invention is respectively 60g.a.i./hm
2, 90g.a.i./hm
2, 120g.a.i./hm
2, after its medicine, the drug effect of 1 day is respectively 72.43%, 84.23%, 89.07%, and as seen along with the increase of dosage, the composition pesticide described in the embodiment of the present invention also strengthens gradually for the drug effect of rice leaf roller.In addition, after contrast medicine, the drug effect of 1 day, 3 days, 7 days is known, and the drug effect of the composition pesticide described in the embodiment of the present invention increases, when the using dosage of composition pesticide is 90g.a.i./hm gradually along with using the increase of number of days
2and 120g.a.i./hm
2time, after medicine, the drug effect of 14 days is all less than the drug effect of after medicine 7 days.
From above-mentioned 2, the drug effect of the composition pesticide described in the embodiment of the present invention obviously increases along with the increase of using dosage, when using dosage reaches 90g.a.i./hm
2, 120g.a.i./hm
2time, the persistence of its drug effect weakens.
Composition pesticide contrast described in the embodiment of the present invention is used alone 20%4-to phenoxy group Phenoxymethyl-2-ethyl-DOX (EC) or 15% Tolfenpyrad (EC), equally also there is good drug effect.As using dosage is all 120g.a.i./hm
2the composition pesticide described in the embodiment of the present invention and 20%4-to phenoxy group Phenoxymethyl-2-ethyl-1, 3-dioxolanes (EC), time 20% Tolfenpyrad (EC), experiment Chinese medicine after 1 day, 3 days, in the test number of 7 days and 14 days, the drug effect of the composition pesticide described in the embodiment of the present invention is compared to being used alone 20%4-to phenoxy group Phenoxymethyl-2-ethyl-1, the drug effect of 3-dioxolanes (EC), all exceed about 20%, and the drug effect of the composition pesticide described in the embodiment of the present invention is compared to drug effect when being used alone 15% Tolfenpyrad (EC), height about 17%.
To sum up, the composition pesticide described in the embodiment of the present invention is obvious for the preventive and therapeutic effect of rice leaf roller, has obvious synergistic effect compared to the composition being used alone composition pesticide.
(2) active constituent content preparing composition pesticide be 50% 4-granule pesticide composition is dispersibled to phenoxy group Phenoxymethyl-2-ethyl-DOX and flonicamid, with the gross weight of composition pesticide for benchmark, comprise following component:
Said components is mixed, obtain required active constituent content be 50% 4-granule pesticide composition is dispersibled to phenoxy group Phenoxymethyl-2-ethyl-DOX and flonicamid.
Composition pesticide described in the embodiment of the present invention is for preventing and treating the test of pesticide effectiveness of Cucumber blight.
Experimental technique: as described in above-described embodiment.
Experimental result: as shown in table 13.
Table 13, the composition described in the present embodiment and 20%4-to phenoxy group Phenoxymethyl-2-ethyl-DOX (EC),
10% chlorine pyridine insect amide (WG) is to the field control effectiveness test table of comparisons of Cucumber blight
Interpretation:
As can be seen from Table 13, in above-mentioned experiment, the using dosage of the composition pesticide described in the embodiment of the present invention is respectively 30g.a.i./hm
2, 60g.a.i./hm
2, 90g.a.i./hm
2, after its medicine, the drug effect of 1 day is respectively 74.58%, 81.29%, 85.78%, and as seen along with the increase of dosage, the composition pesticide described in the embodiment of the present invention also strengthens gradually for the drug effect of Cucumber blight.In addition, after contrast medicine, the drug effect of 1 day, 3 days, 7 days and 14 days is known, and the drug effect of the composition pesticide described in the embodiment of the present invention increases gradually along with using the increase of number of days.
Composition pesticide contrast described in the embodiment of the present invention is used alone the drug effect of 20%4-to phenoxy group Phenoxymethyl-2-ethyl-DOX (EC) or 10% flonicamid (WG), specific as follows:
Using dosage is all 90g.a.i./hm
2the composition pesticide described in the embodiment of the present invention, 20%4-is to phenoxy group Phenoxymethyl-2-ethyl-1, when 3-dioxolanes (EC) and 10% flonicamid (WG), to contrast after three groups of experimental group Chinese medicines the test number of 1 day, 3 days, 7 days and 14 days, the drug effect of the composition pesticide described in the visible embodiment of the present invention is compared to being used alone 20%4-to phenoxy group Phenoxymethyl-2-ethyl-1, the drug effect of 3-dioxolanes (EC), all exceeds about 27%; And the drug effect of the composition pesticide described in the embodiment of the present invention is also higher than drug effect when being used alone 10% flonicamid (WG).
To sum up, the composition pesticide described in the embodiment of the present invention is obvious for the preventive and therapeutic effect of Cucumber blight, has obvious synergistic effect compared to the composition being used alone composition pesticide.
Embodiment 14, preparation formulation is the composition pesticide of suspending agent
(1) active constituent content preparing composition pesticide be the 4-of 35% to the suspension pesticide composition of phenoxy group Phenoxymethyl-2-ethyl-DOX and fipronil bisamide, with the gross weight of composition pesticide for benchmark, comprise following component:
Said components mixed, obtaining required active constituent content is that the 4-of 35% is to the suspension pesticide composition of phenoxy group Phenoxymethyl-2-ethyl-DOX and fipronil bisamide.
(2) active constituent content preparing composition pesticide be the 4-of 20% to the suspension pesticide composition of phenoxy group Phenoxymethyl-2-ethyl-DOX and Rynaxypyr, with the gross weight of composition pesticide for benchmark, comprise following component:
Said components mixed, obtaining required active constituent content is that the 4-of 20% is to the suspension pesticide composition of phenoxy group Phenoxymethyl-2-ethyl-DOX and Rynaxypyr.
Composition pesticide described in the embodiment of the present invention is used for the test of pesticide effectiveness of water prevention chilo suppressalis.
Experimental technique: as described in above-described embodiment.
Experimental result: as shown in table 14.
Table 14, the composition described in the present embodiment and 20%4-to phenoxy group Phenoxymethyl-2-ethyl-DOX (EC),
200g/L Rynaxypyr (SC) is to the field control effectiveness test table of comparisons of striped rice borer
As can be seen from Table 14, in above-mentioned experiment, the using dosage of the composition pesticide described in the embodiment of the present invention is respectively 15g.a.i./hm
2, 30g.a.i./hm
2, 120g.a.i./hm
2, after its medicine, the drug effect of 1 day is respectively 80.61%, 85.68%, 88.59%, and as seen along with the increase of dosage, the composition pesticide described in the embodiment of the present invention strengthens gradually for the drug effect of rice-stem borer.
Comparing in being used alone the dosage of 20%4-to phenoxy group Phenoxymethyl-2-ethyl-DOX experimental group use is 120g.a.i./hm
2but the drug effect of 1 day is only 57.21% after its medicine.
In addition, after contrast medicine, the drug effect of 1 day, 3 days, 7 days is known, and the drug effect of the composition pesticide described in the embodiment of the present invention increases gradually along with using the increase of number of days, and when using dosage is 15g.a.i./hm
2and 30g.a.i./hm
2time, after medicine, the drug effect of 14 days is all less than the drug effect of after medicine 7 days, and the increase of visible using dosage, the persistence of drug effect slightly weakens.
Using dosage is all 60g.a.i./hm
2the composition pesticide described in the embodiment of the present invention and 200g/L Rynaxypyr (SC) time:
After dispenser 1 day, the drug effect of the composition pesticide described in the embodiment of the present invention exceeded about 9% compared to the drug effect being used alone 200g/L Rynaxypyr (SC);
After medicine 3 days, the composition pesticide described in the embodiment of the present invention was increased to 94.03% for the drug effect of rice-stem borer, exceeds the drug effect about 11% when being used alone 200g/L Rynaxypyr (SC);
After medicine 7 days, the drug effect of the composition pesticide described in the embodiment of the present invention was increased to 98.30%, and the drug effect of 200g/L Rynaxypyr (SC) experimental group to rice-stem borer is only 86.71%;
After medicine 14 days, the drug effect of the composition pesticide described in the embodiment of the present invention was still higher than the drug effect about 4% of 200g/L Rynaxypyr (SC) experimental group;
Visible, the drug effect of the composition pesticide described in the embodiment of the present invention is better than 200g/L Rynaxypyr (SC).
To sum up, the composition pesticide drug action described in the embodiment of the present invention is obvious, has obvious synergistic effect compared to the composition being used alone composition pesticide.
Embodiment 15, preparation formulation is the composition pesticide of oil suspending agent
The active constituent content preparing composition pesticide be the 4-of 15% to the oil suspending agent composition pesticide of phenoxy group Phenoxymethyl-2-ethyl-DOX and bromine cyanogen insect amide, with the gross weight of composition pesticide for benchmark, comprise following component:
Said components mixed, obtaining required active constituent content is that the 4-of 15% is to the oil suspending agent composition pesticide of phenoxy group Phenoxymethyl-2-ethyl-DOX and bromine cyanogen insect amide.
To sum up, the composition pesticide drug action described in the embodiment of the present invention is obvious, has obvious synergistic effect compared to the composition being used alone composition pesticide.
In sum, the 4-that contains of the present invention is to 1 of phenoxy-phenoxy methyl structural, the complex preparation product of 3-dioxolane compound and amide-type insecticide there is obvious synergistic effect, therefore, use the insecticidal effect that less dosage can reach required.
Be described in detail specific embodiments of the invention above, but it is as example, the present invention is not restricted to specific embodiment described above.To those skilled in the art, any equivalent modifications that this practicality is carried out and substituting also all among category of the present invention.Therefore, equalization conversion done without departing from the spirit and scope of the invention and amendment, all should contain within the scope of the invention.
Claims (10)
1. contain 4-to the DOX compounds of phenoxy-phenoxy methyl structural and an amide-type insecticide composition, it is characterized in that, the active ingredient of described composition comprises component A and B component;
Wherein, described component A is for containing 4-to phenoxy group Phenoxymethyl-DOX compounds;
Described B component is amide-type insecticide;
The weight ratio of described component A and described B component is 99:1-1:99.
2. composition according to claim 1, is characterized in that, described has the structure shown in structural formula (I) containing the DOX compounds of 4-to phenoxy-phenoxy methyl structural:
Wherein, R is selected from alkyl, thiazolinyl, cycloalkyl and aryl.
3. composition according to claim 1, it is characterized in that, described amide-type insecticide is selected from one or more in Tolfenpyrad, flonicamid, Rynaxypyr, fipronil bisamide, cyanogen insect amide, bromine cyanogen insect amide, fluorine cyanogen insect amide or thiophene insect amide.
4. composition according to claim 2, is characterized in that, described component A and the weight ratio of B component are 8:1-1:8.
5. composition according to claim 4, is characterized in that, described component A and the weight ratio of B component are 8:1-1:1.
6. composition according to claim 2, is characterized in that, described component A and the weight proportion of B component are 1:1-1:40.
7. composition according to claim 6, is characterized in that, described component A and the weight proportion of B component are 1:1-1:8.
8. composition according to claim 6, is characterized in that, described component A and the weight proportion of B component are 1:4-1:20.
9. the composition according to any one of claim 1-8, it is characterized in that, described formulation is any one in solution, emulsion, aqueous emulsion, missible oil, wetting powder, suspending agent, pulvis, paste, soluble powder, granule, outstanding newborn concentrating agents, oil suspending agent, microcapsule formulations, seed treatment.
10. an application for composition as described in claim 1, is characterized in that, for insect or act in its environment, habitat or storage areas; Be applied in stem, leaf, fruit, root, seed or soil one or more, using method comprises dipping, spray, evaporate, be atomized, broadcast sowing, brush in one or more.
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| CN108077265A (en) * | 2017-12-29 | 2018-05-29 | 上海生农生化制品股份有限公司 | A kind of difenolan derivative pesticide composition and its application in pest control |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103271035A (en) * | 2013-06-10 | 2013-09-04 | 海利尔药业集团股份有限公司 | Insecticide composition containing flonicamid and pyriproxyfen |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103271035A (en) * | 2013-06-10 | 2013-09-04 | 海利尔药业集团股份有限公司 | Insecticide composition containing flonicamid and pyriproxyfen |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108077265A (en) * | 2017-12-29 | 2018-05-29 | 上海生农生化制品股份有限公司 | A kind of difenolan derivative pesticide composition and its application in pest control |
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