CN104840530A

CN104840530A - Hemorrhoid ointment and preparation method thereof

Info

Publication number: CN104840530A
Application number: CN201510276944.6A
Authority: CN
Inventors: 石哲文
Original assignee: Individual
Current assignee: Individual
Priority date: 2015-05-27
Filing date: 2015-05-27
Publication date: 2015-08-19

Abstract

The invention relates to a method for preparing a hemorrhoid ointment, comprising the following steps: a. grinding downy rosemyrtle root, herb of runcinate knotweed, Jew's ear on pagodatree, herb of striate loosestrife and Chinese asafoetida in parts by weight and then mixing the powder uniformly, adding 75% ethanol according to a material-liquid ratio of 1 to 9, carrying out reflux extraction for three times, 2-3 hours each time, and mixing reflux liquids; concentrating the reflux liquid mixture into an extract with relative density of 1.20-1.35 (45 DEG C); b. grinding all-grass of Taiwan lettuce, narrowleaf screwtree root and borneol in parts by weight into 600-mesh powder; c. heating common perilla oil in parts by weight to 80-90 DEG C, then adding the powder in the step b and stirring the materials for 30-40 minutes; then adding the extract in the step a, mixing the materials uniformly and cooling the mixture, thus obtaining the hemorrhoid ointment. The hemorrhoid ointment has the functions of relieving swelling and pain, stopping bleeding and clearing away heat and promoting blood circulation and detoxication. As an externally used medicine used for treating hemorrhoids, the hemorrhoid ointment has the advantages that the synergistic effects of all the components are very prominent; the hemorrhoid ointment can achieve the effects of quickly relieving swelling and stopping bleeding when being used for treating hemorrhoids, and has unexpected remarkable effects.

Description

A kind of ZHICHUANG GAO and preparation method thereof

Technical field

The present invention relates to a kind of ZHICHUANG GAO and preparation method thereof, belong to technical field of Chinese medicine.

Background technology

Hemorrhoid are also known as hemorrhoid disease, blood stasis, haemorrhoids, it is the soft vein group occurring with venous plexus under anal canal skin under human rectum's end mucosa to expand and flexing is formed, hemorrhoid comprise internal hemorrhoid, external hemorrhoid, mixed hemorrhoid, are bottom anal orifice and rectal intestine and a kind of chronic disease of the vein group of the venous plexus generation varicose of anal mucosa and one or more softnesses of being formed.Be positioned at the vascular tissue of anal canal, when its swelling or inflammation, can take on morbit forms or become hemorrhoid.With regard to its physiology and appearance, the anus pad that it is made up of arteriovenous passage and connective tissue.Hemorrhoid (being commonly called as hemorrhoid) are a kind of common diseases being positioned at anus position, and any age all can fall ill, but with age, sickness rate increases gradually.In China, hemorrhoid are modal anal and intestinal diseases, have the saying of " ten male nine hemorrhoid ", " ten female ten hemorrhoid ".

(1) general treatment: the hemorrhoid being applicable to the overwhelming majority, comprise the initial stage of thrombotic and strangulated hemorrhoid.Be careful in one's diet, give up alcohol and pungent stimulation food, increase fibrous food, take in fruit and vegerable more, drink more water, change bad bowl evacuation habit, keep free movement of the bowels, take laxative if desired, clean anus after an action of the bowels.For prolapsus type hemorrhoid, hemorrhoid block is gently held in the palm back in attention have gentle hands, stops to deviate from again.Avoid sitting standing for a long time, carry out appropriate exercise, warm water's (can potassium permanganate be contained) demibain etc. before sleeping.(2) topical therapy: be widely adopted, medicine comprises suppository, unguentum and lotion, most containing Chinese medicine ingredients.(3) oral drug therapy: general employing treats cirsoid medicine.(4) injection treatment: better to I, II degree of bleeding internal hemorrhoids effect; By injection of sclerosing agent around Submucosa venous plexus, make cause inflammation reaction and fibrosis, thus press off the vein of varicose; Can repetitive therapy after January, avoid that sclerosing agent is injected mucous layer and cause necrosis.(5) physiotherapy: laser therapy, cryotherapy, galvanism and copper ion electrochemotherapy, Microwave Coagulation therapy, infra-red coagulation are treated, less use.(6) plastic loop ligation: hemorrhoid roots pricked by cover, blocks its blood and is provided with making hemorrhoid to come off necrosis; Be applicable to II, III degree internal hemorrhoid, huge internal hemorrhoid and fibrosis internal hemorrhoid are more suitable for.

Summary of the invention

The object of this invention is to provide a kind of ZHICHUANG GAO and preparation method thereof, can be used for the treatment of hemorrhoid.

ZHICHUANG GAO of the present invention; Be made up of the crude drug of following parts by weight: mountain Shen root 10 ~ 12 parts, Herba Polygoni Runcinati 10 ~ 12 parts, Auricularia Sophorae 15 ~ 18 parts, Herba Lysimachiae Grammicae 6 ~ 8 parts, Resina Ferulae 6 ~ 8 parts, Herba Lactucae formosanae 3 ~ 4 parts, Radix Helicteris 5 ~ 6 parts, Borneolum Syntheticum 2 ~ 3 parts, common perilla seed oil 15 ~ 18 parts.

As this ZHICHUANG GAO of optimization, be made up of the crude drug of following parts by weight: mountain Shen root 11 parts, Herba Polygoni Runcinati 11 parts, Auricularia Sophorae 16 parts, Herba Lysimachiae Grammicae 7 parts, Resina Ferulae 7 parts, Herba Lactucae formosanae 3 parts, Radix Helicteris 5 parts, Borneolum Syntheticum 2 parts, common perilla seed oil 16 parts.

Prepare the method for this ZHICHUANG GAO, comprise the following steps: a, by the mountain Shen root of described parts by weight, Herba Polygoni Runcinati, Auricularia Sophorae, Herba Lysimachiae Grammicae, Resina Ferulae pulverize after mix homogeneously, by solid-liquid ratio 1:9, add 75% ethanol, reflux, extract, 3 times, each 2 ~ 3 hours, merges backflow; Be condensed into the extractum that relative density is 1.20 ~ 1.35 (45 DEG C); B, the Herba Lactucae formosanae of described parts by weight, Radix Helicteris, Borneolum Syntheticum are made 600 object powder; C, the common perilla seed oil of described parts by weight is heated to 80 ~ 90 DEG C, then adds the powder in step b, stir 30 ~ 40 minutes; Then the extractum mix homogeneously of step a is added, cooling.

In the component of ZHICHUANG GAO of the present invention, Herba Lactucae formosanae heat-clearing and toxic substances removing; Wind-damp dispelling; Invigorate blood circulation; Main furuncle carbuncle; Laryngopharynx swelling and pain; Scabies; Venom; Rheumatic arthralgia; Traumatic injury.Mountain Shen eradicates wet dispeling the wind, hemostasis, pain relieving; Treating the liver is scorching, metrorrhagia, stomachache, rheumatic arthritis, and hernia is scalded.Radix Helicteris induces sweat heat clearing away, subduing swelling and detoxicating; Cure cold heating, headache, thirsty, mumps, measles, dysentery, enteritis, carbuncle, scrofula, sore, eczema.Herba Polygoni Runcinati heat-clearing and toxic substances removing, promoting blood circulation and stopping pain, removing toxic substances and promoting subsidence of swelling; For acute gastroenteritis, spitting of blood of spitting blood, bleeding hemorrhoids, menoxenia, traumatic injury; Mastitis are controlled in external, carbuncle furuncle and phyma poison.Auricularia Sophorae stops blooding; Dysentery relieving; Anticancer; Main bleeding hemorrhoids; Have blood in stool; Metrorrhagia; Dysentery; Hepatocarcinoma; Hepatitis.Herba Lysimachiae Grammicae hemostasis is antipyretic, vital energy regualting and blood circulation-promoting, detumescence of drawing out pus by applying a plaster to the affected part, and arresting convulsion is only jerked; Cure mainly traumatic injury, innominate toxic swelling, injury by sword or axe.Resina Ferulae has removing food stagnancy, changes abdominal mass, loose painful abdominal mass, effect of parasite killing; For meat stagnation, blood stasis addiction abdominal mass, mass in abdomen, abdominal pain due to worm stagnation.Borneolum Syntheticum leads to all keys, loose stagnated fire, removing nebula improving eyesight, reducing swelling and alleviating pain; Control apoplexy locked mouth, calentura coma, infantile convulsion expectorant fan, deafness with qi stagnation, sore throat, aphtha, otitis media, carbuncle, hemorrhoid, order is nebula film also, enterobiasis.Common perilla seed oil is considered to the best edible oil being rich in alpha-linolenic acid, intestine moistening; Black hair; Cure mainly dryness of the intestine constipation; Hair is uninteresting; Alpha-linolenic acid (a-LNA) content is up to 50% ~ 70%; Alpha-linolenic acid belongs to the serial unsaturated fatty acid of ω-3, and be one of unsaturated fatty acid of needed by human, human body self can not synthesize, and can only absorb from the external world.

ZHICHUANG GAO of the present invention, reducing swelling and alleviating pain, stop blooding antipyretic, promoting blood circulation and detoxication; As the external preparation being used for the treatment of hemorrhoid, each component synergism is very outstanding; Treatment hemorrhoid can be subsided a swelling rapidly hemostasis, have beyond thought remarkable result.

Pertinent clinical data is as follows: physical data: accept 318 routine patients for medical treatment, wherein man 162 example, female 156 example, 21 ~ 66 years old age, average 42 years old.Stochastic averagina is divided into three groups.Each group of no significant difference in sex, age, the course of disease (P > 0.05), has comparability.

Diagnostic criteria: clinical manifestation is based on local redness, pain, scorching hot, and to some extent with having blood in stool, blood stasis is deviate from, the congested erosion of hemorrhoid mucosa etc.And get rid of the serious heart, brain, lung, hepatic disease and other anorectum department emergency cases.

Therapeutic Method: adopt the ZHICHUANG GAO in the embodiment of the present invention 1,2,3, external, gets this product and be applied in affected part in right amount, once a day, use just before going to bed when needing, 7th be a course for the treatment of.

Efficacy assessment standard: 1. cure: congestion and swelling pain disappears, stopped bleeding, and blood stasis deviates from incarceration Hui Na voluntarily; 2. take a turn for the better: redness, pain, hemorrhage basic disappearance, blood stasis can Hui Na voluntarily; 3. invalid: redness, pain, hemorrhage nothing are alleviated, and blood stasis is deviate from can not Hui Na.Namely take a favorable turn in ninety percent case two days, three groups of cases after seven days comparitive study the results are shown in Table 1.

Detailed description of the invention

The invention will be further described for embodiment plan given below; but can not be interpreted as it is limiting the scope of the invention; those skilled in the art to nonessential improvement and adjustment more of the present invention, still belong to protection scope of the present invention according to content of the present invention.

Embodiment 1:a, get mountain Shen root 110 grams, Herba Polygoni Runcinati 110 grams, Auricularia Sophorae 160 grams, Herba Lysimachiae Grammicae 70 grams, Resina Ferulae 70 grams pulverize after mix homogeneously, by solid-liquid ratio 1:9, add 75% ethanol, reflux, extract, 3 times, each 2 ~ 3 hours, merge backflow; Be condensed into the extractum that relative density is 1.20 ~ 1.35 (45 DEG C); B, get Herba Lactucae formosanae 30 grams, Radix Helicteris 50 grams, Borneolum Syntheticum 20 restrain into 600 object powder; C, get common perilla seed oil 160 grams and be heated to 80 ~ 90 DEG C, then add the powder in step b, stir 30 ~ 40 minutes; Then the extractum of step a, tween 80 0.5 gram of mix homogeneously is added, cooling.External, gets this product and is applied in affected part in right amount, once a day, use just before going to bed when needing.

Embodiment 2:a, get mountain Shen root 100 grams, Herba Polygoni Runcinati 100 grams, Auricularia Sophorae 150 grams, Herba Lysimachiae Grammicae 60 grams, Resina Ferulae 60 grams pulverize after mix homogeneously, by solid-liquid ratio 1:9, add 75% ethanol, reflux, extract, 3 times, each 2 ~ 3 hours, merge backflow; Be condensed into the extractum that relative density is 1.20 ~ 1.35 (45 DEG C); B, get Herba Lactucae formosanae 30 grams, Radix Helicteris 50 grams, Borneolum Syntheticum 20 restrain into 600 object powder; C, get common perilla seed oil 150 grams and be heated to 80 ~ 90 DEG C, then add the powder in step b, stir 30 ~ 40 minutes; Then the extractum mix homogeneously of step a is added, cooling.External, gets this product and is applied in affected part in right amount, once a day, use just before going to bed when needing.

Embodiment 3:a, get mountain Shen root 120 grams, Herba Polygoni Runcinati 120 grams, Auricularia Sophorae 180 grams, Herba Lysimachiae Grammicae 80 grams, Resina Ferulae 80 grams pulverize after mix homogeneously, by solid-liquid ratio 1:9, add 75% ethanol, reflux, extract, 3 times, each 2 ~ 3 hours, merge backflow; Be condensed into the extractum that relative density is 1.20 ~ 1.35 (45 DEG C); B, get Herba Lactucae formosanae 40 grams, Radix Helicteris 60 grams, Borneolum Syntheticum 30 restrain into 600 object powder; C, get common perilla seed oil 180 grams and be heated to 80 ~ 90 DEG C, then add the powder in step b, stir 30 ~ 40 minutes; Then the extractum mix homogeneously of step a is added, cooling.External, gets this product and is applied in affected part in right amount, once a day, use just before going to bed when needing.

Claims

1. a ZHICHUANG GAO; It is characterized in that being made up of the crude drug of following parts by weight: mountain Shen root 10 ~ 12 parts, Herba Polygoni Runcinati 10 ~ 12 parts, Auricularia Sophorae 15 ~ 18 parts, Herba Lysimachiae Grammicae 6 ~ 8 parts, Resina Ferulae 6 ~ 8 parts, Herba Lactucae formosanae 3 ~ 4 parts, Radix Helicteris 5 ~ 6 parts, Borneolum Syntheticum 2 ~ 3 parts, common perilla seed oil 15 ~ 18 parts are made.

2. ZHICHUANG GAO according to claim 1, its spy is to be made up of the crude drug of following parts by weight: mountain Shen root 11 parts, Herba Polygoni Runcinati 11 parts, Auricularia Sophorae 16 parts, Herba Lysimachiae Grammicae 7 parts, Resina Ferulae 7 parts, Herba Lactucae formosanae 3 parts, Radix Helicteris 5 parts, Borneolum Syntheticum 2 parts, common perilla seed oil 16.

3. prepare a method for ZHICHUANG GAO described in claim 1, it is characterized in that:

A, by the mountain Shen root of described parts by weight, Herba Polygoni Runcinati, Auricularia Sophorae, Herba Lysimachiae Grammicae, Resina Ferulae pulverize after mix homogeneously, by solid-liquid ratio 1:9, add 75% ethanol, reflux, extract, 3 times, each 2 ~ 3 hours, merge backflow; Be condensed into the extractum that relative density is 1.20 ~ 1.35 (45 DEG C);

B, the Herba Lactucae formosanae of described parts by weight, Radix Helicteris, Borneolum Syntheticum are made 600 object powder;

C, the common perilla seed oil of described parts by weight is heated to 80 ~ 90 DEG C, then adds the powder in step b, stir 30 ~ 40 minutes; Then the extractum mix homogeneously of step a is added, cooling.