CN104809351A - Vancomycin renal injury early warning system - Google Patents
Vancomycin renal injury early warning system Download PDFInfo
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- CN104809351A CN104809351A CN201510234116.6A CN201510234116A CN104809351A CN 104809351 A CN104809351 A CN 104809351A CN 201510234116 A CN201510234116 A CN 201510234116A CN 104809351 A CN104809351 A CN 104809351A
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Abstract
The invention relates to a vancomycin renal injury early warning system. The system is embedded into a doctor working station system. The vancomycin renal injury early warning system is composed of following modules: drug use of a patient inquiring and displaying module, a blood medicine concentration detection result input module, and a detection result analysis and early warning module. The vancomycin renal injury early warning system aims at helping medical personnel to carry out early warning and treatment on urgent blood medicine concentration of vancomycin, so that the medicine administration of the patients is adjusted according to a detection result and untoward effect (AKI) can be prevented; the most important module is the detection result analysis and early warning module; the detection result analysis and early warning module comprises a detection result displaying sub-module, a detection result analysis sub-module and a detection result reporting sub-module.
Description
Technical field
The present invention relates to medicine injury of kidney early warning system, particularly a kind of blood concentration early warning system of vancomycin medicine.
Background technology
Vancomycin (Vancomycin) is a kind of glycopeptide antibiotics, is applicable to methicillin-resistant staphylococcus aureus and the infection caused by other bacterium: septicemia, infectious endocarditis, osteomyelitis, arthritis, burn, shallow scabies secondary infection, pneumonia, pulmonary abscess, pyothorax, peritonitis, the meningitis such as operation wound.
Vancomycin goes on the market over 50 years, along with the in-depth that clinician is familiar with infection of staphylococcus aureus, the variation of infection population, particularly to the intensification of vancomycin pharmacokinetic difference cognition in different crowd, how science, rationally, standardization ground uses vancomycin to become clinical problem in the urgent need to address.
2011 Chinese " Chinese Journal of New Drugs and Clinical Remedies " has delivered " vancomycin clinical practice China Consensus of experts ", the suitable dose in different crowd for further specification and optimization vancomycin, from the expert of Infectious Disease, division of respiratory disease, Nephrology dept., hematology, severe medical science, microbiology and clinical pharmacology aspect, common discussion has been drafted " vancomycin clinical practice dosage China Consensus of experts ", for clinician's reference again.Be separately that a medicine carrys out out a common recognition, this medicine is in the weight of medical circle as seen.
Blood concentration (Plasma Concentration) means the total concentration after drug absorption in blood plasma, comprise be combined with plasma proteins or at the medicine of plasma free, sometimes also can make a general reference the concentration of medicine in whole blood.Pharmaceutically-active intensity and the medicine concentration in blood plasma is directly proportional, and medicine concentration in vivo changed along with the time.
Bad reaction means by normal usage, the prevention of consumption drug application, diagnosis or disease therapy process, and the adverse reaction irrelevant with therapeutic purposes occurs.Its specific occurrence condition is by normal dose and normal usage medication, eliminates because of drug abuse, excess misuse in terms of content, uses the reaction caused by the situation such as medicine and quality problems not according to prescriptive procedure.
Therapeutic drug monitoring be generally used for treating window narrow, strong toxicity, medicining cycle long, take medicine after the large medicine of individual difference, vancomycin is exactly one of such medicine.If adjust the dosage of this medicine not in time, cause medicine to be accumulated in vivo, then multiple bad reaction may occur.As fash, heating, shiver with cold and anaphylactoid reaction, ototoxicity, renal damage, the digestive tract reactions etc. such as n and V.
For solving in prior art the problem lacked the critical value early warning of the blood concentration sensitive medicaments such as vancomycin, the present invention is based on the doctor workstation system of Meikang, design and a kind of vancomycin injury of kidney early warning system is provided.This system is completed by computer input written-out program, first by patient's plasma drug concentration data input computing machine, program comprises corresponding normal range blood concentration numerical value, by application program, patient's existing information is analyzed, draw judged result, be sent to feature section office computer by output system, the early warning information of this patient's vancomycin can be obtained, with the adjustment of pointing out medical worker to carry out dosage regimen.Present system has simple to operate, and expansion is convenient, shows the features such as directly perceived.
Summary of the invention
The object of the present invention is to provide a kind of vancomycin injury of kidney early warning system.
The object of the invention is the critical value of the blood concentration of paramedical personnel to patient's vancomycin and carry out early warning, change current clinical blood concentration adjustment present situation not in time, reduce the risk that adverse drug reaction occurs patient, finally reach the object of individual administration.
Vancomycin injury of kidney early warning system of the present invention, forms by with lower module:
Patient medication inquiry and display module
Blood concentration testing result load module
Analysis of test results and warning module
Wherein, patient medication inquiry and its function mainly realized of display module can store, add and inquire about master data that patient is correlated with (as height, body weight, related check index etc.) and the related data (as the kind of drug combination, the detected value etc. of method for determination of concentration of vancomycin in plasma) of used medicine.
Wherein, its function mainly realized of blood concentration testing result load module is analyzed the blood sample of patient extracted by detecting instrument, and the assay input doctor workstation system that will obtain.
Wherein, Analysis of test results and its function mainly realized of warning module can judge, if exceed normal range according to the testing result of the blood concentration scope preset to input, then by network, early warning information is sent to designated terminal, prompting medical worker carries out therapeutic scheme adjustment.
Wherein, most important module is Analysis of test results and warning module: it comprises, testing result display module, Analysis of test results module and test results report module.
Its function mainly realized of testing result display module is, the given patient vancomycin related data upgraded is shown.
Its function mainly realized of Analysis of test results module is, according to determination of drug concentration numerical value several times before the concentration range preset and patient, analyzes the plasma drug concentration data of given patient, determines whether the critical value needing report.
Its function mainly realized of test results report module is, if patient's this blood concentration is critical value, then sends early warning information to the terminal of associated department by network, notifies that medical worker adjusts therapeutic scheme, to reach early warning object.
Below vocabulary of terms is explained in detail:
Doctor workstation system: integrate that patient history is write, medical order treatment, medical technologies application and result queries, hold a consultation process, integrated application information system that patient's basic condition is inquired about, developed by Meikang company and license.
Below describe principle of work and the method for work of each module in detail, illustrate simultaneously and adopt setting.
Patient medication inquiry and display module: in patient medication inquiry and display module, the patient wanting to search and relevant information can show, as Fig. 4 by software.
Blood concentration testing result load module: in blood concentration testing result load module, this patient's method for determination of concentration of vancomycin in plasma input doctor workstation system that user can will record, and upgrade display, as Fig. 5.
Analysis of test results and warning module: in Analysis of test results and warning module, system according to the method for determination of concentration of vancomycin in plasma data inputted, can determine whether critical value, reports and points out if then send, as Fig. 5.
By above work, paramedical personnel carries out early warning function to patient's method for determination of concentration of vancomycin in plasma can be reached.
Early warning system of the present invention, relative to existing early warning system, has the following advantages: 1, provide convenient and practical method for early warning.
2, the medicine scope of early warning can expand easily.
Accompanying drawing explanation
Fig. 1 is the structural drawing of early warning system of the present invention
In figure: 1 patient medication inquiry and display module, 2 blood concentration testing result load modules, 3 Analysis of test results and warning module
Fig. 2 is user's login figure of early warning system of the present invention
Fig. 3 is the section office selection figure of early warning system of the present invention
Fig. 4 is the inquiry patient selection figure of early warning system of the present invention
Fig. 5 is drug abuse test information and the early warning figure of early warning system of the present invention
Fig. 6 is patient's doctor's advice query graph of early warning system of the present invention
Fig. 7 is test results report figure
Embodiment
Embodiment 1,
After this system has been disposed, just can carry out the setting management of patient data:
1, keeper finds patient data according to patient's name or medical record number and shows, as Fig. 4.
2, according to testing result method for determination of concentration of vancomycin in plasma data inputted and upgrade.
3, judge testing result and send early warning information.
4, intended recipient can view early warning, as Fig. 5.
Embodiment 2, vancomycin injury of kidney early warning system
System running environment
The employing C language of native system is write, can in unit operation
Environment: XP/win7/win8, resolution 1024 × 768.
Functional overview
The function of native system can be divided into lower part:
Database is arranged: can arrange editor's (database maintenance) to the database of patient.
Blood concentration testing result inputs: can input the patient's method for determination of concentration of vancomycin in plasma value recorded.
Analysis of test results and early warning: can testing result be analyzed, and send early warning information.
Early warning result shows: judged result can be carried out printing and output report.
Embodiment 3, vancomycin injury of kidney early warning system operation instructions
After login system, as Fig. 2
Database is arranged
Patient data can be searched at this page.As Fig. 4.
The patient data of name or the medical record number of specifying can be searched at this page.As Fig. 4.
Blood concentration testing result inputs
The patient's method for determination of concentration of vancomycin in plasma value recorded can be inputted at this page.
Analysis of test results and early warning
Can testing result be analyzed at this page, and send early warning information, as Fig. 5.
Early warning result shows
Judged result can be carried out printing and output report at this page.
Embodiment 4, vancomycin injury of kidney early warning system operation instructions
1, database is arranged
Maintenance data base
Carry out maintenance to the database used to arrange.
Embodiment 5, vancomycin injury of kidney early warning system example
Testing result display example
1, select at testing result interface to upgrade.
2, testing result is shown and more new data, as Fig. 5.
3, will predict the outcome and issue with Word document (* .doc) form and print.
Analysis of test results example
1, at testing result interface selection analysis.
2, analyze testing result and show.
3, will predict the outcome and issue with Word document (* .doc) form and print.
Test results report example
1, report is selected at testing result interface.
2, select section office and send early warning information, as Fig. 3.
3, will predict the outcome and issue with Word document (* .doc) form and print.
Claims (5)
1. a vancomycin injury of kidney early warning system, is connected in sequence by following functions module: patient medication inquiry and display module, blood concentration testing result load module, Analysis of test results and warning module.
2. vancomycin injury of kidney early warning system according to claim 1, wherein patient medication inquiry and the working routine of display module are: search for and read the physiological and pathological data, the drug combination situation showing that send medicine patient and be correlated with, this step is completed by Pharmacy pharmacist.
3. vancomycin injury of kidney early warning system according to claim 1, to the working routine of blood concentration testing result load module be wherein: be input in system by measuring errorless patient's method for determination of concentration of vancomycin in plasma detection data, update server client database data, this step is completed by blood concentration sensing chamber and clinical laboratory related personnel.
4. vancomycin injury of kidney early warning system according to claim 1, wherein Analysis of test results and warning module: the data inputted carried out showing, analyzing, concurrent announcement of delivering newspaper, it comprises following submodule: testing result shows, Analysis of test results, test results report.Wherein the function of testing result display sub-module is, the given patient vancomycin related data upgraded is shown.Wherein the function of Analysis of test results submodule is, according to the concentration range preset, analyzes, determine whether critical value to the plasma drug concentration data of given patient.Wherein the function of test results report submodule is, if critical value then sends the terminal of early warning information to associated department, to reach early warning object by network.This step is completed by blood concentration sensing chamber related personnel.
5. vancomycin injury of kidney early warning system according to claim 1, pharmacist is by receiving and reading the early warning report transmitted, and adjust the medicining condition of patient's vancomycin, this system can assist the individual administration of vancomycin.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510234116.6A CN104809351A (en) | 2015-05-11 | 2015-05-11 | Vancomycin renal injury early warning system |
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| CN201510234116.6A CN104809351A (en) | 2015-05-11 | 2015-05-11 | Vancomycin renal injury early warning system |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105139083A (en) * | 2015-08-10 | 2015-12-09 | 石庆平 | Method and system for reevaluating safety of drug after appearance on market |
| CN105335616A (en) * | 2015-11-02 | 2016-02-17 | 北京大学第一医院 | Child vancomycin individualized concentration prediction system |
| CN107689249A (en) * | 2016-08-02 | 2018-02-13 | 四川智康科技有限责任公司 | A kind of clinical critical value early warning system and method for early warning based on internet |
| CN111341407A (en) * | 2020-02-20 | 2020-06-26 | 常州市第一人民医院 | Early warning system for acute kidney injury in hospital |
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| CN101125086A (en) * | 2006-08-18 | 2008-02-20 | 刘胜 | Closed-loop automatic controlling insulin-injecting system |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105139083A (en) * | 2015-08-10 | 2015-12-09 | 石庆平 | Method and system for reevaluating safety of drug after appearance on market |
| CN105335616A (en) * | 2015-11-02 | 2016-02-17 | 北京大学第一医院 | Child vancomycin individualized concentration prediction system |
| CN107689249A (en) * | 2016-08-02 | 2018-02-13 | 四川智康科技有限责任公司 | A kind of clinical critical value early warning system and method for early warning based on internet |
| CN111341407A (en) * | 2020-02-20 | 2020-06-26 | 常州市第一人民医院 | Early warning system for acute kidney injury in hospital |
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Application publication date: 20150729 |
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