CN104800673A - Traditional Chinese medicine for treating knee osteoarthritis and chronic synovitis - Google Patents

Abstract

The invention relates to a traditional Chinese medicine for treating knee osteoarthritis and chronic synovitis. The traditional Chinese medicine is prepared by mixing the following raw materials according to a conventional method: radix cyathulae, semen coicis, rhizoma atractylodis, golden cypress, lumbricus, astragalus membranaceus, notopterygium root, trogopterus dung, Chinese angelica, yam rhizome, rhizoma alismatis, grifola, ligusticum wallichii, liquorice, myrrh, peach kernel, safflower carthamus and pawpaw. The composition is simple; herbal medicines in a prescription are a few; the cost is low; the curative effect is good; the total efficiency of clinic application is 90.9%; the cure rate is 45%.

Description

A kind of Chinese medicine for the treatment of knee joint osseous arthritis and merging chronic synovitis

technical field:

the present invention relates to a kind of Chinese medicine for the treatment of knee joint osseous arthritis and merging synovitis, belong to technical field of Chinese medicines.

background technology:

knee joint osseous arthritis is based on the pathological changes of the degeneration of knee joint bone and cartilage.The common chronic strain of primary disease, wound, articular surface cause by force unbalance, Joint disorder, knee instability etc., be more common in middle-aged and elderly people, particularly the fat person of women, or be secondary to endocrinopathy, and hyperpietic is multiple.Early stage synovial membrane is without change, and secondary synovitis thereafter, occur hemorrhage, edema, hypertrophy, plumpness, fibrosis, synovial fluid increases.The exudate of synovitis changes the character of normal synovial fluid, and articular cartilage lacks nutrition, damages.Modern medicine is thought: (1) synovial membrane stimulates to be levied and due to the release of desmoenzyme, may comprise lysosome, and it makes synovial membrane cell that is congested and synovial layer react; (2) synovial membrane also can produce degenerative enzyme and regulatory factor, as IL-1, directly affects chondrocyte; (3) other potential reason also comprises the deposition of free radical and immune complex.Belong to the category such as the traditional Chinese medical science " arthromyodynia ", " myopathy ".Based on caused by liver and kidney deficiency; The cohesion of the stagnation of QI, blood stasis, phlegm-damp is mark.Principle pathological mechanism, liver governing tendons, kidney governing bones, caused by liver and kidney deficiency, be difficult main bone nourishing muscle and tendon, then muscles and bones cervical carcinoma with cachexia flaccidity is weak, joint joint stuffiness, and muscle BI-syndrome involved the blood vessels hinders, and sends out as rheumatism involving the bone.

the chronic synovitis that knee joint arthritis merges.Knee joint osseous arthritis belongs to the traditional Chinese medical science " rheumatism involving the bone ", " edema " category, how to be mixed by wet three gas of wind and cold and to be formed.Generally hold wet person under the arm many, or the people of obesity, dampness is betted in joint and is fallen ill.Water is wet to be delaied, and muscle arteries and veins relaxes weak, controls suitable dispeiling pathogenic wind and removing dampness, strong flesh muscle; If cold-evil comparatively contains, control suitable cold expelling, Eradicates wind, dehumidifying; If ailment said due to cold or exposure is contained partially, controlling should expelling wind and removing dampness.Primary disease is treated, and how to demonstrate,prove two aspects from excess syndrome and deficiency complicated with excess and sets about.Control suitable the liver and the kidney tonifying, or activating blood circulation to dissipate blood stasis and dredge the collateral, functions dispelling wind and clearing away cold, removing dampness is principle.The author treats above-mentioned sick decades, good results from intending Chinese medicine " decoction for treating arthritis ".

summary of the invention:

a kind of Chinese medicine for the treatment of knee joint osseous arthritis and merging chronic synovitis, it is characterized in that the Chinese medicine that the raw material thing that it is made up of following weight ratio is made according to a conventional method: Radix Cyathulae 15-20 gram, Semen Coicis 20-30 gram, Rhizoma Atractylodis 12-15 gram, Cortex Phellodendri 6-10 gram, Pheretima 12-15 gram, Radix Astragali 30-50 gram, Rhizoma Et Radix Notopterygii 12-15 gram, Oletum Trogopterori 10-12 gram, Radix Angelicae Sinensis 15-20 gram of Rhizoma Dioscoreae Septemlobae 12-15 gram, Rhizoma Alismatis 6-10 gram, Polyporus 12-15 gram, Rhizoma Chuanxiong 10-15 gram, Radix Glycyrrhizae 6-10 gram, Myrrha 10-15 gram, Semen Persicae 10-15 gram, Flos Carthami 12-15 gram, Fructus Chaenomelis 12-15 gram.

in medicine of the present invention: Radix Cyathulae: bitter, acid, flat.Enter liver, kidney.There is promoting blood circulation to restore menstrual flow, dredge the effect of muscle profit numbness, conducting blood to flow downwards, diuresis.Semen Coicis: sweet, light, is slightly cold.Enter spleen, lung, kidney channel.Have inducing diuresis to remove edema, Eradicates wet eliminating impediment, evacuation of pus detumescence, invigorating the spleen to arrest diarrhea effect.Rhizoma Atractylodis: pungent, bitter.Temperature.Enter spleen, stomach warp.There is the effect of expelling wind and dampness, invigorating the spleen to arrest diarrhea, expelling cold and relieving exterior syndrome, block removing improving eyesight.Cortex Phellodendri: bitter, cold.Enter kidney, gallbladder, urinary bladder channel.Heat clearing away expels the heat-evil, the effect of heat clearing and damp drying, removing toxic substances doctor skin ulcer.Pheretima: salty, cold.Enter liver, lung, kidney channel.Have heat clearing away spasmolytic, dredging collateral treats numbness, clearing lung, relieving asthma, the effect of inducing diuresis for treating stranguria syndrome.The Radix Astragali: sweet, temperature.Enter spleen, lung meridian.Tonifying Qi and lifting yang, strengthening superficial resistance to stop perspiration, poison holding is had to rise the effect of flesh, inducing diuresis to remove edema.Rhizoma Et Radix Notopterygii: pungent, bitter, temperature.Enter bladder, liver,spleen,kidney warp.There is the effect of expelling cold and relieving exterior syndrome, numbness relieving and pain relieving.Oletum Trogopterori: sweet, temperature.Enter Liver Channel.There is the effect of promoting blood circulation, eliminating stasis to stop pain.Radix Angelicae Sinensis: sweet, pungent, bitter temperature.Enter liver, the heart, spleen.There is the effect of tonifying blood and regulating menstruation, promoting blood circulation and stopping pain, loosening bowel to relieve constipation.Rhizoma Dioscoreae Septemlobae: bitter, puts down into liver, stomach warp.The effect of favourable turbid damp, Eradicates rheumatism.Rhizoma Alismatis: sweet, cold.Enter kidney, urinary bladder channel.There is the effect that promoting diuresis to eliminate damp pathogen expels the heat-evil.Polyporus; Gan Ping.Enter kidney, urinary bladder channel.There is the effect of promoting diuresis to eliminate damp pathogen.Rhizoma Chuanxiong: pungent, temperature.Enter liver, gallbladder, pericardium channel.There is the effect of blood-activating and qi-promoting, wind-expelling pain-stopping.Radix Glycyrrhizae: sweet, flat.Enter 12 warps.There is the effect of spleen reinforcing lung moistening, Yiqi and vein recovery, relieving spasm to stop pain, heat-clearing and toxic substances removing, coordinating the actions of various ingredients in a prescription.Myrrha: bitter, pungent is flat.Enter liver, the heart, spleen channel.There is the effect of loose blood and dissolving stasis, reducing swelling and alleviating pain.Semen Persicae: bitter flat.Enter the heart, liver large intestine channel.There is the effect of removing blood stasis, loosening bowel to relieve constipation.Flos Carthami: Xin Wen.Enter conscience warp.There is the effect of promoting blood circulation to restore menstrual flow, regulating blood flow to alleviate pains.Fructus Chaenomelis: acid, temperature.Enter liver, spleen channel.Eradicates is had to wet the effect of relaxing muscles and tendons, stomach function regulating of being amusing.All medicines are in harmonious proportion, and play the curative effect of the liver and the kidney tonifying, blood circulation promoting and blood stasis dispelling, expelling wind and cold, removing damp and stopping pain altogether.

method for making and method of administration: the present invention is decoction, all prescription quantity is all selected to be formed, and conventional method decocts with water twice, 30 minutes first times, and second time 20 minutes, the medicinal liquid leached for twice mixes 300 milliliters, and every bu is taken for 3 times, each 100 milliliters.

beneficial effect: side's prescription of the present invention is simple, and flavour of a drug are few, and price is low, good effect, clinical practice total effective rate 90.9%, cure rate 45%.

detailed description of the invention:

do into an explanation below in conjunction with embodiment to the present invention:

implement 1: a kind of knee joint osseous arthritis for the treatment of merges the Chinese medicine of chronic synovitis, the medicament that the raw material be made up of following weight ratio is made according to a conventional method: Radix Achyranthis Bidentatae 15-20 gram, Rhizoma Atractylodis 12-15 gram, Cortex Phellodendri 6-10 gram, Pheretima 12-15 gram, Radix Astragali 30-50 gram, Rhizoma Et Radix Notopterygii 12-15 gram, Radix Gentianae Macrophyllae 12-15 gram, Oletum Trogopterori 10-12 gram, Radix Angelicae Sinensis 15-20 gram, Rhizoma Dioscoreae Septemlobae 12-15 gram, Rhizoma Alismatis 6-10 gram, Polyporus 12-15 gram, Semen Coicis 20-30 gram, Rhizoma Chuanxiong 10-15 gram, Myrrha 10-15 gram, Semen Persicae 10-15 gram, Flos Carthami 12-15 gram.

embodiment 2: a kind of Chinese medicine for the treatment of knee joint osseous arthritis and merging chronic synovitis, wherein the preferred weight proportioning of various material medicine is: Radix Achyranthis Bidentatae 20 grams, Rhizoma Atractylodis 12 grams, Cortex Phellodendri 6 grams, Pheretima 15 grams, the Radix Astragali 50 grams, Rhizoma Et Radix Notopterygii 12 grams, Radix Gentianae Macrophyllae 15 grams, Oletum Trogopterori 10 grams, Rhizoma Alismatis 6 grams, Polyporus 12 grams, Semen Coicis 30 grams, Radix Angelicae Sinensis 15 grams of, Rhizoma Dioscoreae Septemlobae 15 grams, Rhizoma Chuanxiong 10 grams, Myrrha 10 grams, 15 grams, Semen Persicae, 15 grams, Flos Carthami.

clinical efficacy is summed up:

-, physical data: Chinese medicine of the present invention is applied to clinical for many years, and treatment patient tens of example, effect is good.

two, diagnostic criteria: all check two cover standards according to " People's Republic of China's traditional Chinese medicine industry standard disease of tcm Standardization of diagnosis and curative effect " rheumatism involving the bone diagnosis basis and the clinical and clinical roentgenology met in the international diagnostic criteria of knee joint osseous arthritis of nineteen ninety-five American Rheumatism Association's proposition.This group all has arthroncus, pain and function limitation in various degree.

three, curative effect judging standard:

1, cure: transference cure, follow up a case by regular visits to and do not recur for 1 year.

, take a turn for the better: transference cure, follow up a case by regular visits to recurrence half a year, or symptom alleviates.

four, therapeutic effect:

4-6 agent of taking medicine was 1 course for the treatment of, and the lighter's 15 doses of transference cure recoveries from illness, severe one 50 doses of transference cures, recovery from illness, follows up a case by regular visits to and do not recur for 1 year.Always there is rate 90.9%, cure rate 45%.

five, model case:

case 1, Lee's ××, man 50 years old, on August 25th, 2005 goes to a doctor.Right knee joint swelling, pain, difficulty in walking, catch cold over 5 years heavier, once takes the medicine poor effect such as synovitis sheet, ibuprofen tablet and examine.Look into: body of the tongue is light red, tongue is white micro-greasy, deep-slow pulse.Through radiation and physico-chemical examination, be diagnosed as knee joint osseous arthritis and merge synovitis.Give the improvement of 15 doses, above-mentioned Chinese medicine, 50 doses of healings, follow up a case by regular visits to and do not recur for 1 year.

case 2, king's ××, female 45 years old, in October, 2013 examines.The left gonalgia, activity increases the weight of 1 year, and once arrive many places hospital and examine as knee joint osseous arthritis merges chronic synovitis, take traditional Chinese medicine and medicine for external use, poor effect is examined.Look into: left knee joint micro-swollen, not red, pale tongue, white and thin fur, deep and stringy pulse.Through radiation and physico-chemical examination.Examine as knee joint osseous arthritis merges chronic synovitis.To the recovery from illness of 20 doses, above-mentioned Chinese medicine.So far do not recur.

Claims (1)

1. the Chinese medicine for the treatment of knee joint osseous arthritis and merging chronic synovitis, it is characterized in that the Chinese medicine that the raw material thing that it is made up of following weight ratio is made according to a conventional method: Radix Cyathulae 15-20 gram, Semen Coicis 20-30 gram, Rhizoma Atractylodis 12-15 gram, Cortex Phellodendri 6-10 gram, Pheretima 12-15 gram, Radix Astragali 30-50 gram, Rhizoma Et Radix Notopterygii 12-15 gram, Oletum Trogopterori 10-12 gram, Radix Angelicae Sinensis 15-20 gram of Rhizoma Dioscoreae Septemlobae 12-15 gram, Rhizoma Alismatis 6-10 gram, Polyporus 12-15 gram, Rhizoma Chuanxiong 10-15 gram, Radix Glycyrrhizae 6-10 gram, Myrrha 10-15 gram, Semen Persicae 10-15 gram, Flos Carthami 12-15 gram, Fructus Chaenomelis 12-15 gram.