CN104800623A - Preparation method of traditional Chinese medicine composition for treating tuberculous pleuritis - Google Patents
Preparation method of traditional Chinese medicine composition for treating tuberculous pleuritis Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition electuary for treating tuberculous pleuritis. The traditional Chinese medicine composition electuary is prepared from the following principal raw materials in parts by weight: 15 parts of radices trichosanthis, 9 parts of colla corii asini, 9 parts of radix glehniae, 30 parts of lalang grass rhizome, 15 parts of rhizoma bletillae, 20 parts of curculigo capitulate, 15 parts of cutworm, 15 parts of fresh camptotheca, 9 parts of marginate American agave leaf, 9 parts of semen lepidii, 9 parts of dayflower, 30 parts of pear and 900 parts of rock candy. The traditional Chinese medicine composition electuary has the characteristics of being easy to operate, remarkable in curative effect and free of side effect, can relieve untoward effect of hydrothorax absorption, shorten course of disease, reduce pleural adhesion and pleural thickening, and relieve chest pain; the hydrothorax absorption of a patient is quick, the chest pain symptom is remarkably improved, and the probability of pleural thickening or pleural adhesion is remarkably reduced, so that the side effect caused by western medicine therapy is overcome, and the traditional Chinese medicine composition electuary has certain curative effect for treating tuberculous exudative pleurisy.
Description
this case is divisional application, original bill application number 2013107131428, applying date 2013.12.14, a kind of Traditional Chinese medicine composition paste for the treatment of tuberculous pleuritis of denomination of invention and preparation method thereof.
Technical field
The invention discloses a kind of Traditional Chinese medicine composition paste, especially Traditional Chinese medicine composition paste for the treatment of tuberculous pleuritis and preparation method thereof.The invention belongs to traditional Chinese medicine field.
Background technology
Tuberculous pleuritis is extrapulmonary tuberculosis common clinically, is the pleura inflammation that mycobacterium tuberculosis and metabolite thereof enter the pleural space that is in hypersensitive state and cause.The immune state of the morbidity of tuberculous pleuritis and m tuberculosis infection and body is closely related.Tuberculous pleuritis belongs to the V-type of the sick five large types of tuberculous pleuritis, though its non-pulmonary lesion, has close relationship clinically with tuberculous pleuritis.
After tuberculous pleuritis can betide mycobacterium tuberculosis primary infection, also can occur in any stage of the tuberculosis course of disease.Tuberculous dry pleurisy can be divided into, tuberculous exadative pleurisy and tuberculous empyema according to clinical process and pathological manifestations.Due to two stages that tuberculous dry pleurisy and tuberculous exadative pleurisy are a kind of diseases, the former course of disease is of short duration, and the clinical manifestation of tuberculous exadative pleurisy and pathological process are comparatively distinct, thus the former is clinical in usually being covered by the latter, therefore normal by tuberculous dry pleurisy and tuberculous exadative pleurisy (being called for short dry pleurisy and exudative pleurisy) clinically, be referred to as tuberculous pleuritis.
Dry pleurisy: the allergy of light-duty dry pleurisy to mycobacterium tuberculosis is lower, can without obvious clinical symptoms, or only has slight fever and slight chest pain and usually out in the cold, and some patients can show high heat and obviously violent chest pain.Chest pain, often in sharp-pointed acupuncture sample pain, increases the weight of when dark air-breathing and cough, the position that pain dimensions involves depending on inflammation.Cause parietal pleura neural involvement during costal pleurisy, and intercostal nerves, spinal nerves and cause chest and back, flank pain can be involved; Then stimulate phrenic nerves during diaphragmatic pleuritis and feed through to phrenic nerves further and cause neck-shoulder pain, sometimes also can cause epigastrium pain; The pain of anterior part of chest and breastbone is caused during mediastinal pleurisy; Interlobar pleurisy is often without obvious chest pain.Physical examination: hypopnea, Ipsilateral local has tenderness and respiratory murmur to lower, and audible and pleuritic rub, air-breathing is all more obvious with expiration.The clinical course of dry pleurisy is of short duration, within general 1 ~ 2 day, can transfer exudative pleurisy to.
Exudative pleurisy: most exudative pleurisy is the continuity of dry pleurisy, and the dry pleurisy process that exudative pleurisy patient is early stage, often out in the cold or undiscovered.Exudative pleurisy shows as morbidity sharply, high heat, and mostly at 38 DEG C ~ 40 DEG C not etc., even several weeks sustainable a few days, body temperature is often directly proportional to hydrops amount body temperature, and patient can with general malaise, the tuberculosis poisoning symptoms such as weak, night sweat, loss of appetite.Chest pain and dry cough can be there is when early stage sepage is less.Along with increasing gradually of hydrothorax, parietal pleura and visceral pleura are separated by it, chest pain thereupon disappearing dyspnea day by day obvious, how much relevant its degree is with hydrops amount, hydrops amount is few or can non-evident sympton and sign when being positioned between leaf, and when hydrops increases particularly after a large amount of hydrothorax compressing lungs, heart, blood vessel because Respiratory area and heart output reduce, cause mediastinum to be shifted to strong side, there is out of breath and serious dyspnea in patient, the speed formed with hydrops is more fast more obvious.Physical examination: early stage Breathing movement lowers, audible pleuritic rub, touches friction sense; During a large amount of hydrops Ipsilateral thorax and intercostal full, respiratory movement weakens; Apex beat and trachea are shifted to strong side, and the percussion of hydrops district is voiced sound or flatness, as can be disappeared hepatic dullness on right side, as the then TraubeShi tympanitic resonance district decline in left side; Vocal fremitus and respiratory murmur lower or disappear.Interlobar effusion and infrapulmonary fluid accumulation sign not obvious.
Authorization Notice No. CN 102018876 B(application number 201010583126.8) Chinese patent literature provide a kind of Traditional Chinese medicine composition paste for the treatment of pulmonary tuberculosis, tuberculous pleuritis, raw material consists of Radix Panacis Quinquefolii 8-15g, Radix Ginseng 5-8g, Radix Astragali 20-30, Margarita 5-8g, Semen Juglandis 5-7g, Herba Epimedii 20-30g, Oviductus Ranae 5-7g, Cordyceps 2-3g, linum 15-25g, Colla Corii Asini 5-10g, Fructus Mori 20-30g, Bulbus Lilii 10-20g, Fructus Arctii 5-15g and assorted nectar 2-3g.Authorization Notice No. CN 101642513 A(application number 20061002786.3) Chinese patent literature provide a kind of medicine for the treatment of tuberculous pleurisy pleurorrhea; by Lignum Aquilariae Resinatum 20-35 gram; Cortex Tiliae omeiensis Radicis 150-240 gram; ground marrow human skeleton 150-250 gram; Flos Hibisci Rosae-Sinensis 60-100 gram, (clearly) Rhizoma Pinelliae 60-105 gram.Authorization Notice No. CN 103041341 A(application number 201210585187.7) Chinese patent literature provide a kind of Traditional Chinese medicine composition paste being used for the treatment of tuberculous exadative pleurisy and preparation method thereof, : the crude drug of described Traditional Chinese medicine composition paste comprises Flos Farfarae, Cortex Mori, Rhizoma Dioscoreae, Radix Kansui, Rhizoma Panacis Majoris, Folium Eriobotryae, the Radix Stemonae, Fructus Jujubae, Flos Inulae, Caulis Mahoniae, Rhizoma Zingiberis, Rhizoma Sparganii, Flos Carthami, Folium Perillae, Bulbus Allii Macrostemonis, Herba Selaginellae, Caulis Polygoni Multiflori, Exocarpium Citri Grandis, Radix Changii, Poria, Semen Coicis, Rhizoma Curcumae Longae, Fructus Schisandrae Chinensis, Semen Lepidii (Semen Descurainiae), Rhizoma Polygonati Odorati, the Rhizoma Anemarrhenae, Herba Commelinae, Rhizoma Polygoni Cuspidati, Radix Adenophorae, Semen Pharbitidis.
In a word, Chinese medicine achieves good curative effect in treatment primary disease, but also there are some problems: clinically to alleviating the reaction of hydrothorax malabsorption, the curative effect shortened acquired by the course of disease is also unsatisfactory, does not also have better formula to treatment tuberculous exadative pleurisy.
summary of the invention,
For the present situation of existing treatment tuberculous pleuritis deficiency, an object of the present invention is to provide a kind of Traditional Chinese medicine composition paste for the treatment of tuberculous pleuritis, there is easy to operate, the evident in efficacy and feature had no side effect, the reaction of hydrothorax malabsorption can also be alleviated, shorten the course of disease, reduce pleural adhesion, pleural thickening, chest pain, patient's hydrothorax absorbs fast, chest pain symptom is improved obviously, the probability that pachynsis pleurae or adhesion occur obviously reduces, thus overcome the side effect that western medicine brings, to treatment tuberculous pleuritis, there is certain curative effect.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
Treat a Traditional Chinese medicine composition paste for tuberculous pleuritis, take off the primary raw material stating weight proportion and be prepared from: Radix Trichosanthis 10-15 part, Colla Corii Asini 3-9 part, Radix Glehniae 4-9 part, Rhizoma Imperatae 10-30 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 6-15 part, great Ye Rhizoma Curculiginis 10-20 part, Stachys geobombycis C. Y. Wu 5-15 part, fresh Fructus seu radix camptothecae acuminatae (Fructus Camptothecae Acuminatae) 5-15 part, Folium Agaves variegatae 1-9 part, Semen Lepidii (Semen Descurainiae) 1-9 part, Herba Commelinae 1-9 part, pears 10-30 part, crystal sugar 100-900 part.
Treat a Traditional Chinese medicine composition paste for tuberculous pleuritis, preferred scheme is, takes off the primary raw material stating weight proportion and is prepared from: Radix Trichosanthis 11-14 part, Colla Corii Asini 4-7 part, Radix Glehniae 5-8 part, Rhizoma Imperatae 15-25 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 9-12 part, great Ye Rhizoma Curculiginis 13-18 part, Stachys geobombycis C. Y. Wu 8-13 part, fresh Fructus seu radix camptothecae acuminatae (Fructus Camptothecae Acuminatae) 8-13 part, Folium Agaves variegatae 3-7 part, Semen Lepidii (Semen Descurainiae) 3-7 part, Herba Commelinae 3-7 part, pears 15-25 part, crystal sugar 300-700 part.
Treat a Traditional Chinese medicine composition paste for tuberculous pleuritis, better preferred scheme is, takes off the primary raw material stating weight proportion and is prepared from: Radix Trichosanthis 13 parts, 6 parts, Colla Corii Asini, Radix Glehniae 6 parts, Rhizoma Imperatae 20 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 10 parts, great Ye Rhizoma Curculiginis 15 parts, Stachys geobombycis C. Y. Wu 10 parts, fresh Fructus seu radix camptothecae acuminatae (Fructus Camptothecae Acuminatae) 10 parts, Folium Agaves variegatae 5 parts, Semen Lepidii (Semen Descurainiae) 5 parts, Herba Commelinae 5 parts, pears 20 parts, 500 parts, crystal sugar.
The preparation method of above-mentioned Traditional Chinese medicine composition paste, preferred scheme is that step is as follows:
1. pears section be placed in together with crystal sugar in container, add the warm water of 30 DEG C, intense fire decocts 10-20 minute, turns slow fire boiling 30 minutes, after filtration, obtains filtrate for subsequent use;
2. Radix Trichosanthis, Radix Glehniae, Rhizoma Imperatae, Pseudobulbus Bletillae (Rhizoma Bletillae), great Ye Rhizoma Curculiginis, Stachys geobombycis C. Y. Wu, fresh Fructus seu radix camptothecae acuminatae (Fructus Camptothecae Acuminatae), Folium Agaves variegatae, Semen Lepidii (Semen Descurainiae) are placed in non iron container together with Herba Commelinae, be blended into cold water, the water surface did not have powder 1-5 cun, soak 20-40 minute, intense fire is fried open, turn 30-50 minute at a simmer, leach medicinal liquid;
3. recrement is blended into cold water again, and the water surface did not have medical material 1.5 cun, and intense fire is fried open, and turns 20-40 minute at a simmer, leaches medicinal liquid, twice medicinal liquid mixing for standby use;
4. by step 1. gained filtrate join step 3. in mixing medicinal liquid in, slow fire is decocted slowly, ceaselessly stirs and prevents from burning, and decocts and stops to during stirring effort, flame-out for subsequent use;
5. Colla Corii Asini is placed in a small amount of boiled water, is stirred well to it and melts completely, pour in the mixture 4., do not stop to stir, utilize waste heat to continue to mix decoction harvest paste, load porcelain vase, after cooling, sealing, takes out after being buried in the earth 5-10 day.
Above-mentioned preparation method, preferred scheme is, step 1. intense fire decocts 13-17 minute (preferably 15 minutes).
Above-mentioned preparation method, preferred scheme is, the step 2. water surface there was not powder 2-4 cun (preferably 3 cun).
Above-mentioned preparation method, preferred scheme is, 2. step soaks 25-35 minute (preferably 30 minutes).
Above-mentioned preparation method, preferred scheme is, 2. step turns 35-55 at a simmer minute (preferably 40 minutes).
Above-mentioned preparation method, preferred scheme is, 3. step turns 25-35 at a simmer minute (preferably 30 minutes).
Above-mentioned preparation method, preferred scheme is, step is taken out after being 5. buried in the earth 6-9 day (preferably 7 days).
Using method: for making the present invention reach optimum therapeuticing effect, Traditional Chinese medicine composition paste of the present invention, gets 12 grams every day, melts with boiled water, is divided into 3 parts, takes half an hour ante cibum morning, noon and afternoon, within 10 days, is a course for the treatment of.
This Traditional Chinese medicine composition paste is to the Be very effective for the treatment of tuberculous pleuritis, can not only cough-relieving pain relieving, hemostasis of regulating the flow of vital energy, can also heat-clearing and toxic substances removing, set about from the reason of the old complaint " innate deficiency, healthy energy loss " of tuberculous pleuritis, control in table benefit, real accomplishes treating both the principal and secondary aspects of a disease.
Treat a Traditional Chinese medicine composition paste for tuberculous pleuritis, the pharmacological effect of each crude drug is respectively:
Radix Trichosanthis: sweet in the mouth, bitter in the mouth, cold nature.There is clearing away heat and promoting production of body fluid, effect of detumescence and apocenosis, for calentura excessive thirst, lung-heat type cough.
Colla Corii Asini: sweet in the mouth, property is put down.To enrich blood YIN nourishing, moisturize, effect of hemostasis, for blood deficiency and yellow complexion, dizzy cardiopalmus, xeropulmonary cough, chronic cough is spat blood.
Radix Glehniae: sweet in the mouth, bitter in the mouth, cold nature.There is nourishing YIN and clearing away lung-heat, effect of reinforcing stomach reg fluid, for lung-heat type cough, chronic cough expectorant blood.
Rhizoma Imperatae: sweet in the mouth, cold in nature.There is cooling blood for hemostasis, effect of clearing away heat and promoting diuresis, spit blood for heat in blood, calentura excessive thirst, edema.
Pseudobulbus Bletillae (Rhizoma Bletillae): bitter in the mouth, sweet, puckery, cold nature.Have astringing to arrest bleeding, effect of detumescence and promoting granulation, for haematemesis of spitting blood, sore swollen toxin, tuberculous pleuritis is spat blood.
Great Ye Rhizoma Curculiginis: moistening the lung and resolving phlegm, relieving cough and asthma, calm spleen invigorating, tonifying the kidney to consolidate the essence.For dyspnea and cough due to deficiency of the kidney, soreness of waist and knee joint, leucorrhea, seminal emission.
Stachys geobombycis C. Y. Wu: kidney tonifying lung moistening, nourishing YIN and supplementing blood, clearing heat and relieving fidgetness.For pulmonary tuberculosis cough, the deficiency of the lung is panted, and spits blood, night sweat, anemia, infantile malnutrition.
Fresh Fructus seu radix camptothecae acuminatae (Fructus Camptothecae Acuminatae): cure mainly: deficiency of the liver and kindey, vertigo and tinnitus, blurring of vision, soreness of the waist and knees, turn white luxated tooth, stranguria caused by overstrain foul leukorrhea, spitting of blood, spits blood, epistaxis, hematuria, dysentery, metrorrhagia, traumatic hemorrhage.
Folium Agaves variegatae: lung moistening, reduces phlegm, cough-relieving.For cough due to consumptive disease, haematemesis, asthma.
Semen Lepidii (Semen Descurainiae): acrid in the mouth, bitter, cold in nature, return lung meridian, heart channel, Liver Channel, stomach warp, urinary bladder channel, there is eliminating the pathogens from the lung sending down the abnormal ascending QI, eliminating phlegm and relieving asthma, inducing diuresis to remove edema, let out the effect by heresy, cure mainly the dyspnea and cough with excessive sputum that sputum stops up lung, lung abscess, edema, breast abdomen hydrops, dysuria, chronic pulmonary heart disease, the cards such as breathing heavily of heart failure is swollen, scrofula tuberculosis.
Herba Commelinae: latin name Commelnae Herba, sweet in the mouth, light, cold in nature, enter the heart, liver,spleen,kidney, intestine and small intestine warp, have heat-clearing and toxic substances removing, effect of inducing diuresis to remove edema.Cure mainly edema, beriberi, dysuria, flu, erysipelas, parotitis, icterohepatitis, hematodiarrhoea, malaria, epistaxis, hematuria, metrorrhagia, leucorrhea, laryngopharynx swelling and pain, the cards such as carbuncle furuncle.
Pears: cure mainly cough due to heat, quench the thirst.Control and cough heat, aphasia due to apoplexy, typhoid fever is generated heat, and separates borax steam, frightened evil.Profit defecation, except harmful wind, only vexed asthma is fanatical.The cool heart of lung moistening, inflammation falls in expectorant, separates sore, alcoholism.
Crystal sugar: sweet in the mouth, property is put down.Be the crystallization reproduced goods of Saccharum Sinensis Roxb., have the unnecessary acidity of neutralization, reduce internal heat, invigorating the spleen and replenishing QI, stomach function regulating lung moistening, effect of relieving cough and resolving phlegm, for the dryness of the lung, the deficiency of the lung, also plays a part in the present invention to be in harmonious proportion and sticks together.
Traditional Chinese medicine composition paste of the present invention is based on the principle of traditional Chinese medical herbal treatment tuberculous pleuritis.The Chinese medicinal material selected all has nourishing the lung to arrest cough, effect of hydrothorax absorption of stopping blooding, alleviate, and cheap, and life-time service also can not cause the financial burden of patient, is to treat the ideal medicine of tuberculous pleuritis.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
embodiment 1
Treat a Traditional Chinese medicine composition paste for tuberculous pleuritis, take off the primary raw material stating weight proportion (getting 10g for every part) and be prepared from: Radix Trichosanthis 10 parts, 3 parts, Colla Corii Asini, Radix Glehniae 4 parts, Rhizoma Imperatae 10 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 6 parts, great Ye Rhizoma Curculiginis 10 parts, Stachys geobombycis C. Y. Wu 5 parts, fresh Fructus seu radix camptothecae acuminatae (Fructus Camptothecae Acuminatae) 5 parts, Folium Agaves variegatae 1 part, Semen Lepidii (Semen Descurainiae) 1 part, Herba Commelinae 1 part, pears 10 parts, 100 parts, crystal sugar.
The preparation process of above-mentioned Traditional Chinese medicine composition paste is as follows:
1. pears section be placed in together with crystal sugar in container, add the warm water of 30 DEG C, intense fire decocts 10 minutes, turns slow fire boiling 30 minutes, after filtration, obtains filtrate for subsequent use;
2. Radix Trichosanthis, Radix Glehniae, Rhizoma Imperatae, Pseudobulbus Bletillae (Rhizoma Bletillae), great Ye Rhizoma Curculiginis, Stachys geobombycis C. Y. Wu, fresh Fructus seu radix camptothecae acuminatae (Fructus Camptothecae Acuminatae), Folium Agaves variegatae, Semen Lepidii (Semen Descurainiae) are placed in together with Herba Commelinae in non iron container, are blended into cold water, the water surface did not have powder 1 cun, soak 20 minutes, intense fire is fried open, and turns 30 minutes at a simmer, leaches medicinal liquid;
3. recrement is blended into cold water again, and the water surface did not have medical material 1.5 cun, and intense fire is fried open, and turns 20 minutes at a simmer, leaches medicinal liquid, twice medicinal liquid mixing for standby use;
4. by step 1. gained filtrate join step 3. in mixing medicinal liquid in, slow fire is decocted slowly, ceaselessly stirs and prevents from burning, and decocts and stops to during stirring effort, flame-out for subsequent use;
5. Colla Corii Asini is placed in a small amount of boiled water, is stirred well to it and melts completely, pour in the mixture 4., do not stop to stir, utilize waste heat to continue to mix decoction harvest paste, load porcelain vase, after cooling, sealing, takes out after being buried in the earth 5.
typical case oneliu XX, man, 42 years old, Yinan County, Linyi.Symptom: lassitude, the whole body is unable, tired, is reluctant activity have slight heating, chest pain, and go examination in hospital to find hydrothorax, olive drab(O．D), slant acidity are tuberculous pleuritis after diagnosing.Sick age: 5 months.Examine the time: on April 23rd, 2011.Because patient does not afford to do expensive Operation Fee, doctor just advises taking Traditional Chinese medicine composition paste of the present invention.
Take embodiment 1 gained Traditional Chinese medicine composition paste 10 days, the whole body is unable, and tired symptom alleviates, and chest pain sense disappears to some extent; Use 1 month, malaise symptoms disappears completely; Consolidate again use 10 days after recovering, drug withdrawal is so far without recurrence.
embodiment 2
Treat a Traditional Chinese medicine composition paste for tuberculous pleuritis, take off the primary raw material stating weight proportion (getting 20g for every part) and be prepared from: Radix Trichosanthis 15 parts, 9 parts, Colla Corii Asini, Radix Glehniae 9 parts, Rhizoma Imperatae 30 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 15 parts, great Ye Rhizoma Curculiginis 20 parts, Stachys geobombycis C. Y. Wu 15 parts, fresh Fructus seu radix camptothecae acuminatae (Fructus Camptothecae Acuminatae) 15 parts, Folium Agaves variegatae 9 parts, Semen Lepidii (Semen Descurainiae) 9 parts, Herba Commelinae 9 parts, pears 30 parts, 900 parts, crystal sugar.
The preparation process of above-mentioned Traditional Chinese medicine composition paste is as follows:
1. pears section be placed in together with crystal sugar in container, add the warm water of 30 DEG C, intense fire decocts 20 minutes, turns slow fire boiling 30 minutes, after filtration, obtains filtrate for subsequent use;
2. Radix Trichosanthis, Radix Glehniae, Rhizoma Imperatae, Pseudobulbus Bletillae (Rhizoma Bletillae), great Ye Rhizoma Curculiginis, Stachys geobombycis C. Y. Wu, fresh Fructus seu radix camptothecae acuminatae (Fructus Camptothecae Acuminatae), Folium Agaves variegatae, Semen Lepidii (Semen Descurainiae) are placed in together with Herba Commelinae in non iron container, are blended into cold water, the water surface did not have powder 5 cun, soak 40 minutes, intense fire is fried open, and turns 50 minutes at a simmer, leaches medicinal liquid;
3. recrement is blended into cold water again, and the water surface did not have medical material 1.5 cun, and intense fire is fried open, and turns 40 minutes at a simmer, leaches medicinal liquid, twice medicinal liquid mixing for standby use;
4. by step 1. gained filtrate join step 3. in mixing medicinal liquid in, slow fire is decocted slowly, ceaselessly stirs and prevents from burning, and decocts and stops to during stirring effort, flame-out for subsequent use;
5. Colla Corii Asini is placed in a small amount of boiled water, is stirred well to it and melts completely, pour in the mixture 4., do not stop to stir, utilize waste heat to continue to mix decoction harvest paste, load porcelain vase, after cooling, sealing, takes out after being buried in the earth 10.
typical case twowoods XX, female, 39 years old, Mouping District, Yantai City.Patient's readme just started fever in 2006/07/28 day, most high fever be at that time 39 degree and height repeatedly, think it is that flu is just treated with Ceftriaxone and B6 and febrifuge, but body temperature is still repeatedly, goes institute's inspection to say it is pericardial effusion.Hospitalization looked into reason in 27 days afterwards.Paracentesis pericardii hydrothorax belongs to negative, does bone marrow aspiration and also shows normally, and thyroid also normally but can not check to belong to what character on earth.Finally arriving that Jinan finds is after pulmonary tuberculosis, and doctor told is gone home medication treatment.I has eaten the medicine (rifampicin of 2 months, isoniazid, pyrazine Xian amine) go back to check to say it is hydrothorax, then the medicine of hospitalization is quiet of rifampicin and isoniazid again, pyrazine and hydrochloric acid amine butanols sheet are oral, but the improvement that the sensation state of an illness is not any recently, can not go to work normally, father and mother see does not have anything to take a turn for the better, just ask someone to ask about in native place, after learning Traditional Chinese medicine composition paste of the present invention, just bought for 4 each courses for the treatment of and taken to patient.
Take 2 courses for the treatment of of embodiment 2 gained invention Traditional Chinese medicine composition paste, patient temperature skin protection is normal, and do not occur the symptom of generating heat again, hydrothorax disappears substantially, and after continuing to take 2 courses for the treatment of, malaise symptoms disappears completely, without recurrence after drug withdrawal.
embodiment 3
Treat a Traditional Chinese medicine composition paste for tuberculous pleuritis, take off the primary raw material stating weight proportion (getting 30g for every part) and be prepared from: Radix Trichosanthis 11 parts, 4 parts, Colla Corii Asini, Radix Glehniae 5 parts, Rhizoma Imperatae 15 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 9 parts, great Ye Rhizoma Curculiginis 13 parts, Stachys geobombycis C. Y. Wu 8 parts, fresh Fructus seu radix camptothecae acuminatae (Fructus Camptothecae Acuminatae) 8 parts, Folium Agaves variegatae 3 parts, Semen Lepidii (Semen Descurainiae) 3 parts, Herba Commelinae 3 parts, pears 15 parts, 300 parts, crystal sugar.
The preparation process of above-mentioned Traditional Chinese medicine composition paste is as follows:
1. pears section be placed in together with crystal sugar in container, add the warm water of 30 DEG C, intense fire decocts 13 minutes, turns slow fire boiling 30 minutes, after filtration, obtains filtrate for subsequent use;
2. Radix Trichosanthis, Radix Glehniae, Rhizoma Imperatae, Pseudobulbus Bletillae (Rhizoma Bletillae), great Ye Rhizoma Curculiginis, Stachys geobombycis C. Y. Wu, fresh Fructus seu radix camptothecae acuminatae (Fructus Camptothecae Acuminatae), Folium Agaves variegatae, Semen Lepidii (Semen Descurainiae) are placed in together with Herba Commelinae in non iron container, are blended into cold water, the water surface did not have powder 2 cun, soak 25 minutes, intense fire is fried open, and turns 35 minutes at a simmer, leaches medicinal liquid;
3. recrement is blended into cold water again, and the water surface did not have medical material 1.5 cun, and intense fire is fried open, and turns 25 minutes at a simmer, leaches medicinal liquid, twice medicinal liquid mixing for standby use;
4. by step 1. gained filtrate join step 3. in mixing medicinal liquid in, slow fire is decocted slowly, ceaselessly stirs and prevents from burning, and decocts and stops to during stirring effort, flame-out for subsequent use;
5. Colla Corii Asini is placed in a small amount of boiled water, is stirred well to it and melts completely, pour in the mixture 4., do not stop to stir, utilize waste heat to continue to mix decoction harvest paste, load porcelain vase, after cooling, sealing, takes out after being buried in the earth 6.
typical case threecui XX, man, 45 years old, Qingdao, Shandong Province Jiaozhou City.Symptom: initial just spy easily feels tired, weak, afterwards noon frequent low grade fever, loss of appetite, body weight is also become thin fast, evening night sweat, mental status extreme difference, spitting of blood, chest and back pain is tuberculous pleuritis after diagnosing.Sick age: 5 months.Examine the time: on March 28th, 2011.
Use embodiment 3 gained Traditional Chinese medicine composition paste, every day 12 grams, melt with boiled water, be divided into 3 parts, take half an hour ante cibum morning, noon and afternoon; Use 3 days, chest and back pain symptom alleviates to some extent; Use 10 days, appetite increases, and weak, fatigue symptom disappears; Use 1 month, malaise symptoms all disappears, and consolidates again 15 days after recovering, and drug withdrawal is so far without recurrence.
embodiment 4
Treat a Traditional Chinese medicine composition paste for tuberculous pleuritis, take off the primary raw material stating weight proportion (getting 40g for every part) and be prepared from: Radix Trichosanthis 14 parts, 7 parts, Colla Corii Asini, Radix Glehniae 8 parts, Rhizoma Imperatae 25 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 12 parts, great Ye Rhizoma Curculiginis 18 parts, Stachys geobombycis C. Y. Wu 13 parts, fresh Fructus seu radix camptothecae acuminatae (Fructus Camptothecae Acuminatae) 13 parts, Folium Agaves variegatae 7 parts, Semen Lepidii (Semen Descurainiae) 7 parts, Herba Commelinae 7 parts, pears 25 parts, 700 parts, crystal sugar.
The preparation process of above-mentioned Traditional Chinese medicine composition paste is as follows:
1. pears section be placed in together with crystal sugar in container, add the warm water of 30 DEG C, intense fire decocts 17 minutes, turns slow fire boiling 30 minutes, after filtration, obtains filtrate for subsequent use;
2. Radix Trichosanthis, Radix Glehniae, Rhizoma Imperatae, Pseudobulbus Bletillae (Rhizoma Bletillae), great Ye Rhizoma Curculiginis, Stachys geobombycis C. Y. Wu, fresh Fructus seu radix camptothecae acuminatae (Fructus Camptothecae Acuminatae), Folium Agaves variegatae, Semen Lepidii (Semen Descurainiae) are placed in together with Herba Commelinae in non iron container, are blended into cold water, the water surface did not have powder 4 cun, soak 35 minutes, intense fire is fried open, and turns 45 minutes at a simmer, leaches medicinal liquid;
3. recrement is blended into cold water again, and the water surface did not have medical material 1.5 cun, and intense fire is fried open, and turns 35 minutes at a simmer, leaches medicinal liquid, twice medicinal liquid mixing for standby use;
4. by step 1. gained filtrate join step 3. in mixing medicinal liquid in, slow fire is decocted slowly, ceaselessly stirs and prevents from burning, and decocts and stops to during stirring effort, flame-out for subsequent use;
5. Colla Corii Asini is placed in a small amount of boiled water, is stirred well to it and melts completely, pour in the mixture 4., do not stop to stir, utilize waste heat to continue to mix decoction harvest paste, load porcelain vase, after cooling, sealing, takes out after being buried in the earth 9.
typical case four:in XX, Heze City, Shandong Province people, male 58 years old, peasant, patient's readme, there is symptom uncomfortable in chest nearly half a year, feel time serious to be out of breath, sometimes slight fever is also had, nearest sensation is more and more come more serious, son sees that patient so feels bad, just band patient comprehensive inspection of having gone to hospital to do, chest films showed: right upper lung tuberculosis, pleural thickening (right side) is in moderate hydrothorax, ESR:90mm/h, repeatedly olive drab(O．D) breast water is extracted out at different parts behind B ultrasonic location, doctor advised patient carries out hands art, because village economic condition is poor, so patient determines not performed an operation, but the state of an illness is more and more serious, situation is not fine, where son learns Traditional Chinese medicine composition paste of the present invention friend, just bought 2 courses for the treatment of to father to try,
After using 2 courses for the treatment of of the present embodiment 4 gained Traditional Chinese medicine composition paste, just sensation QI and blood is clear and coherent for patient, symptom uncomfortable in chest disappears substantially, there is not the situation of having a fever yet, after continuing 2 courses for the treatment of of use, patient's symptom that does not feel like oneself disappears completely, mood has also and then improved, and it is more healthy that health also becomes.Continue to employ 1 course for the treatment of as consolidation, without recurrence after drug withdrawal.
embodiment 5
Treat a Traditional Chinese medicine composition paste for tuberculous pleuritis, take off the primary raw material stating weight proportion (getting 50g for every part) and be prepared from: Radix Trichosanthis 13 parts, 6 parts, Colla Corii Asini, Radix Glehniae 6 parts, Rhizoma Imperatae 20 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 10 parts, great Ye Rhizoma Curculiginis 15 parts, Stachys geobombycis C. Y. Wu 10 parts, fresh Fructus seu radix camptothecae acuminatae (Fructus Camptothecae Acuminatae) 10 parts, Folium Agaves variegatae 5 parts, Semen Lepidii (Semen Descurainiae) 5 parts, Herba Commelinae 5 parts, pears 20 parts, 500 parts, crystal sugar.
The preparation process of above-mentioned Traditional Chinese medicine composition paste is as follows:
1. pears section be placed in together with crystal sugar in container, add the warm water of 30 DEG C, intense fire decocts 15 minutes, turns slow fire boiling 30 minutes, after filtration, obtains filtrate for subsequent use;
2. Radix Trichosanthis, Radix Glehniae, Rhizoma Imperatae, Pseudobulbus Bletillae (Rhizoma Bletillae), great Ye Rhizoma Curculiginis, Stachys geobombycis C. Y. Wu, fresh Fructus seu radix camptothecae acuminatae (Fructus Camptothecae Acuminatae), Folium Agaves variegatae, Semen Lepidii (Semen Descurainiae) are placed in together with Herba Commelinae in non iron container, are blended into cold water, the water surface did not have powder 3 cun, soak 30 minutes, intense fire is fried open, and turns 40 minutes at a simmer, leaches medicinal liquid;
3. recrement is blended into cold water again, and the water surface did not have medical material 1.5 cun, and intense fire is fried open, and turns 30 minutes at a simmer, leaches medicinal liquid, twice medicinal liquid mixing for standby use;
4. by step 1. gained filtrate join step 3. in mixing medicinal liquid in, slow fire is decocted slowly, ceaselessly stirs and prevents from burning, and decocts and stops to during stirring effort, flame-out for subsequent use;
5. Colla Corii Asini is placed in a small amount of boiled water, is stirred well to it and melts completely, pour in the mixture 4., do not stop to stir, utilize waste heat to continue to mix decoction harvest paste, load porcelain vase, after cooling, sealing, takes out after being buried in the earth 7.
test example 1the clinical practice of Traditional Chinese medicine composition paste water preparation of embodiment 5 gained treatment tuberculous pleuritis: in June, 2008 in December ,-2011, screen 120 routine patients in 4 hospitals, wherein women 58 example, male 62 example, oldest 72 years old, minimal ages 38 years old, 55.2 years old mean age.Before test 2 weeks, Continuous Observation is carried out to this crowd, record symptom and change, be divided into two groups at random, experimental group and matched group, experimental group takes embodiment 5 products obtained therefrom, and matched group takes other medicine (conventional medication such as Rimactazid and pyrazine Xian amine).Using method is: get 12 grams every day, melt with boiled water, is divided into 3 parts, takes half an hour ante cibum morning, noon and afternoon, within 10 days, is a course for the treatment of.Curative effect situation criterion: cure: do CT examination display normal, malaise symptoms disappears, energy and muscle power obviously strengthen; Effective: malaise symptoms alleviates or partial disappearance, energy and muscle power strengthen; Invalid: malaise symptoms is unchanged.Result is as shown in table 1.
Table 1: take embodiment 5 product 38-72 year tuberculous pleuritis patient treatment outcome
| Experimental group | Matched group | |
| Number of cases | 100 | 20 |
| Male's number of cases | 52 | 10 |
| Women's number of cases | 48 | 10 |
| Age (year) | 38-72 | 38-72 |
| Clinical cure number of cases | 72 | 5 |
| Effective number of cases | 27 | 11 |
| Invalid number of cases | 1 | 4 |
| Total effective rate | 99% | 80% |
Therapeutic effect: cure 72 examples (72%), effective 27 examples (27%), invalid 1 example (1%), total effective rate 99%.Successful is better than matched group.
Take period self-induction symptom and physical change of spirit as shown in table 2.
Table 2:
Take Traditional Chinese medicine composition paste of the present invention 10 days, more than 53% feel takes a turn for the better to some extent, and malaise symptoms improves; Take 20 days, more than 72% feel takes a turn for the better to some extent, and malaise symptoms improves or disappears, and spirit, muscle power strengthen; Take 30 days, more than 97% feel takes a turn for the better to some extent, and malaise symptoms improves or disappears, and spirit, muscle power strengthen, and do CT examination display normal, some patients self-induction is fully recovered.Take more than 30 days in experimental group, effective percentage can reach 93%, and matched group is only 76%.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.
Claims (8)
1. treat a Traditional Chinese medicine composition paste for tuberculous pleuritis, it is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Radix Trichosanthis 15 parts, 9 parts, Colla Corii Asini, Radix Glehniae 9 parts, Rhizoma Imperatae 30 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 15 parts, great Ye Rhizoma Curculiginis 20 parts, Stachys geobombycis C. Y. Wu 15 parts, fresh Fructus seu radix camptothecae acuminatae (Fructus Camptothecae Acuminatae) 15 parts, Folium Agaves variegatae 9 parts, Semen Lepidii (Semen Descurainiae) 9 parts, Herba Commelinae 9 parts, pears 30 parts, 900 parts, crystal sugar.
2. the preparation method of Traditional Chinese medicine composition paste according to claim 1, it is characterized in that, step is as follows:
1. pears section be placed in together with crystal sugar in container, add the warm water of 30 DEG C, intense fire decocts 10-20 minute, turns slow fire boiling 30 minutes, after filtration, obtains filtrate for subsequent use;
2. Radix Trichosanthis, Radix Glehniae, Rhizoma Imperatae, Pseudobulbus Bletillae (Rhizoma Bletillae), great Ye Rhizoma Curculiginis, Stachys geobombycis C. Y. Wu, fresh Fructus seu radix camptothecae acuminatae (Fructus Camptothecae Acuminatae), Folium Agaves variegatae, Semen Lepidii (Semen Descurainiae) are placed in non iron container together with Herba Commelinae, be blended into cold water, the water surface did not have powder 1-5 cun, soak 20-40 minute, intense fire is fried open, turn 30-50 minute at a simmer, leach medicinal liquid;
3. recrement is blended into cold water again, and the water surface did not have medical material 1.5 cun, and intense fire is fried open, and turns 20-40 minute at a simmer, leaches medicinal liquid, twice medicinal liquid mixing for standby use;
4. by step 1. gained filtrate join step 3. in mixing medicinal liquid in, slow fire is decocted slowly, ceaselessly stirs and prevents from burning, and decocts and stops to during stirring effort, flame-out for subsequent use;
5. Colla Corii Asini is placed in a small amount of boiled water, is stirred well to it and melts completely, pour in the mixture 4., do not stop to stir, utilize waste heat to continue to mix decoction harvest paste, load porcelain vase, after cooling, sealing, takes out after being buried in the earth 5-10 day.
3. preparation method according to claim 2, is characterized in that: step 1. intense fire decocts 13-17 minute (preferably 15 minutes).
4. preparation method according to claim 2, is characterized in that: the step 2. water surface there was not powder 2-4 cun (preferably 3 cun).
5. preparation method according to claim 2, is characterized in that: 2. step soaks 25-35 minute (preferably 30 minutes).
6. preparation method according to claim 2, is characterized in that: 2. step turns 35-55 at a simmer minute (preferably 40 minutes).
7. preparation method according to claim 2, is characterized in that: 3. step turns 25-35 at a simmer minute (preferably 30 minutes).
8. preparation method according to claim 2, is characterized in that: step is taken out after being 5. buried in the earth 6-9 day (preferably 7 days).
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