CN104800443B - A kind of raw marrow symplectic bone agent of kidney tonifying - Google Patents

A kind of raw marrow symplectic bone agent of kidney tonifying Download PDF

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CN104800443B
CN104800443B CN201510167338.0A CN201510167338A CN104800443B CN 104800443 B CN104800443 B CN 104800443B CN 201510167338 A CN201510167338 A CN 201510167338A CN 104800443 B CN104800443 B CN 104800443B
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radix
bone
kidney tonifying
fracture
radix angelicae
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CN104800443A (en
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赵志勇
李静
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Abstract

The invention discloses a kind of raw marrow symplectic bone agent of the kidney tonifying of accelerating union of bone fracture, it is made of the bulk pharmaceutical chemicals of following parts by weight: native copper 45-55g, rhizome of davallia 12-18g, teasel 10-15g, Semen Cuscutae 10-15g, Schisandra chinensis 10-15g, radix cyathulae 12-18g, Radix Salviae Miltiorrhizae 12-18g, Caulis Spatholobi 12-18g, Eupolyphoge sinensis 12-18g, olibanum 10-15g, myrrh 10-15g, safflower 10-15g, Radix Angelicae Sinensis 10-15g, Radix Astragali 25-35g, Radix Paeoniae Alba 12-18g, rhizoma alismatis 10-15g, Herba Lycopi 10-15g, Radix Angelicae Pubescentis 10-15g, Rhizoma Chuanxiong 10-15g, Radix Glycyrrhizae 8-10g, it is decocted in water for oral dose, the present invention passes through reasonable compatibility, the synergistic effect of each Chinese medicine, treating both manifestation and root cause of disease, it can pass through Adjusting and reinforcing liver and kidney promotes growth of spur, improves the activity and quantity of osteoblast, promotes calcified bone matrix, accelerates poroma transformation, moreover it is possible to alleviate local pain, have more advantages than simple compound and biological agent.

Description

A kind of raw marrow symplectic bone agent of kidney tonifying
Technical field
The invention belongs to technical field of traditional Chinese medicines, the raw marrow symplectic bone agent of the kidney tonifying of specifically a kind of accelerating union of bone fracture.
Background technique
Whole body sexual trauma caused by wound violence, contingency, traumatic injury is common clinical frequently-occurring disease, severe trauma Not only threat to life, and rehabilitation course is with the passing of time, many complication and sequelae often occurs, seriously affects quality of life, clinic is controlled It is intricate to treat, therefore often occurs fracturing in wound middle and later periods recovery process, in the course of disease and not connect, and wound repeated infection is not cured It closes, soft tissue bruise does not restore, and the absorption of local hematoma difficulty, treatment of traumatic pain and dysfunction etc., differential diagnosis in tcm category liver kidney is not Foot, stagnation of the circulation of vital energy blood is tired, and muscles and bones is lost, wet poison retention feeding in honor and do not gone.
There are many fresh fracture, old fracture, fracture delayed union and the treatment method of disunion, and corresponding drug is also very It is more, other than the most basic reduction of the fracture, fixation, the big principle of functional training three, separately there are traction therapeutic, Boards wall, gypsum solid Still there is sizable delayed union and bone nonunion fractured than regular meeting after fixed, jig braking and various operative treatments fracture, As dislocation again occurs for the activity of patient or disunion or even deformity cause amputation during treating and healing, trouble is given The life of person brings inevitable massive losses, while also increasing certain burden for society.
Motherland's medicine thinks that the growth and development of the kidney generating marrow and dominating bone, bone is all related with kidney.Traumatic injury, local swelling are Stagnation of the circulation of vital energy blood is called, not general rule pain.
Summary of the invention
The purpose of the present invention is to overcome the deficiency of existing above-mentioned technology, and the kidney tonifying for providing a kind of accelerating union of bone fracture is raw Marrow symplectic bone agent.
To solve the above problems, the technical scheme adopted by the invention is that:
A kind of raw marrow symplectic bone agent of the kidney tonifying of accelerating union of bone fracture, is made: native copper 45- of the bulk pharmaceutical chemicals of following parts by weight 55g, rhizome of davallia 12-18g, teasel 10-15g, Semen Cuscutae 10-15g, Schisandra chinensis 10-15g, radix cyathulae 12-18g, Radix Salviae Miltiorrhizae 12- 18g, Caulis Spatholobi 12-18g, Eupolyphoge sinensis 12-18g, olibanum 10-15g, myrrh 10-15g, safflower 10-15g, Radix Angelicae Sinensis 10-15g, Radix Astragali 25-35g, Radix Paeoniae Alba 12-18g, rhizoma alismatis 10-15g, Herba Lycopi 10-15g, Radix Angelicae Pubescentis 10-15g, Rhizoma Chuanxiong 10-15g, Radix Glycyrrhizae 8-10g, decocting Clothes.
It is that the present invention advanced optimizes above scheme below:
A kind of raw marrow symplectic bone agent of the kidney tonifying of accelerating union of bone fracture, is made: native copper of the bulk pharmaceutical chemicals of following parts by weight 50g, rhizome of davallia 15g, teasel 12g, Semen Cuscutae 12g, Schisandra chinensis 12g, radix cyathulae 15g, Radix Salviae Miltiorrhizae 15g, Caulis Spatholobi 15g, Eupolyphoge sinensis 15g, olibanum 12g, myrrh 12g, safflower 12g, Radix Angelicae Sinensis 12g, Radix Astragali 30g, Radix Paeoniae Alba 15g, rhizoma alismatis 12g, Herba Lycopi 12g, Radix Angelicae Pubescentis 12g, Rhizoma Chuanxiong 12g, Radix Glycyrrhizae 9g, is decocted in water for oral dose.
Another prioritization scheme: a kind of raw marrow symplectic bone agent of the kidney tonifying of accelerating union of bone fracture, by the raw material of following parts by weight Medicine is made: native copper 45g, rhizome of davallia 12g, teasel 10g, Semen Cuscutae 10g, Schisandra chinensis 10g, radix cyathulae 12g, Radix Salviae Miltiorrhizae 12g, chicken Blood rattan 12g, Eupolyphoge sinensis 12g, olibanum 10g, myrrh 10g, safflower 10g, Radix Angelicae Sinensis 10g, Radix Astragali 25g, Radix Paeoniae Alba 12g, rhizoma alismatis 10g, Herba Lycopi 10g, Radix Angelicae Pubescentis 10g, Rhizoma Chuanxiong 10g, Radix Glycyrrhizae 8g are decocted in water for oral dose.
Another prioritization scheme: a kind of raw marrow symplectic bone agent of the kidney tonifying of accelerating union of bone fracture, by the raw material of following parts by weight Medicine is made: native copper 55g, rhizome of davallia 18g, teasel 15g, Semen Cuscutae 15g, Schisandra chinensis 15g, radix cyathulae 18g, Radix Salviae Miltiorrhizae 18g, chicken Blood rattan 18g, Eupolyphoge sinensis 18g, olibanum 15g, myrrh 15g, safflower 15g, Radix Angelicae Sinensis 15g, Radix Astragali 35g, Radix Paeoniae Alba 18g, rhizoma alismatis 15g, Herba Lycopi 15g, Radix Angelicae Pubescentis 15g, Rhizoma Chuanxiong 15g, Radix Glycyrrhizae 10g are decocted in water for oral dose.
In above-mentioned prescription: native copper has effects that removing blood stasis and acesodyne, reunion of fractured tendons and bones;The rhizome of davallia has The strong bone of kidney tonifying, promoting blood circulation The effect of analgesic;Teasel, which has, cures mainly aching pain in waist and back;Podomere flaccidity syndrome and arthralgia syndrome;Fall the effect of flutterring wound, damage muscle folding bone, ulcer sore swells; The function that there is Semen Cuscutae continuous wound absolutely, tonifying for the deficiency, benefit to be good for people.The power of Schisandra chinensis energy strengthening by means of tonics, medical value is high, has salubrity strong The benefits of body.Radix cyathulae is used for injury from falling down, rheumatic arthralgia.Radix Salviae Miltiorrhizae has promoting blood circulation, and inducing meastruation to relieve menalgia, relieving restlessness and restlessness, cool blood disappears The effect of carbuncle.Caulis Spatholobi has the effect of activating blood and relaxing tendons, nourishing blood for regulating menstruation;Eupolyphoge sinensis has promoting blood circulation to remove blood stasis, inducing meastruation to relieve menalgia effect.Cream Perfume has effects that promoting blood circulation, promoting the circulation of qi, analgesic;Myrrh has effects that dissolving stasis, detumescence, analgesic therapy;Safflower has blood circulation, dissipates the stasis of blood The effect of analgesic;Radix Angelicae Sinensis has effects that replenishing and activating blood, menstruction regulating and pain relieving, moisturizing dryness and lubricating intestine;Radix Astragali have enhancing body's immunity, The effect of liver protection, diuresis, anti-aging, resisting stress;
Radix Paeoniae Alba has blood-supplementing blood-nourishing, suppressing liver-YANG, the analgesic of soft liver, astringing YIN to stop sweating and other effects;There is rhizoma alismatis qi-restoratives to damage the exhaustion or lesion of the five internal organs, The effect of except the five internal organs feeling of fullness;Herba Lycopi has the effect of wind dispelling analgesia;Radix Angelicae Pubescentis has the effect of dispelling wind and eliminating dampness, arthritis relieves pain;Rhizoma Chuanxiong With blood-activating and qi-promoting, the effect of wind-expelling pain-stopping, Radix Glycyrrhizae has the effect of clearing heat and detoxicating.
Using the above scheme, native copper is synthetism panacea to the present invention, is monarch.The rhizome of davallia, teasel, Semen Cuscutae, Schisandra chinensis, The raw marrow of radix cyathulae kidney tonifying is minister, Radix Salviae Miltiorrhizae, Caulis Spatholobi, Eupolyphoge sinensis, olibanum, myrrh, safflower, Radix Angelicae Sinensis, Radix Astragali, Radix Paeoniae Alba, rhizoma alismatis, Herba Lycopi, Radix Angelicae Pubescentis activating microcirculation and removing stasis medicinal, promoting flow of qi and blood circulation analgesic are assistant.Rhizoma Chuanxiong, Radix Glycyrrhizae are gas medicine in blood, and coordinating the drug actions of a prescription is to make, and the present invention is with kidney tonifying This, assistant is mark with promoting flow of qi and blood circulation dredging collateral.Treating both manifestation and root cause of disease, medicine disease are in step with, then control and test.We cure mainly fracture surgery poroma and generate slowly, The extended patient of healing time has special efficacy.
By clinical test, the present invention has good curative effect to accelerating union of bone fracture, and toxic side effect is small, prevents long-term clothes Injury with drug to taste internal organs, medication are safer.Each course for the treatment of is 30 days, and a course for the treatment of is applied with primary, external application 1~3 It can be cured after a course for the treatment of, cure rate is up to 88.5% or more.
The present invention passes through reasonable compatibility, the synergistic effect of each Chinese medicine, and treating both manifestation and root cause of disease can be promoted by adjusting and reinforcing liver and kidney Growth of spur improves the activity and quantity of osteoblast, promotes calcified bone matrix, accelerates poroma transformation, moreover it is possible to alleviate part pain Bitterly, there are more advantages than simple compound and biological agent.
Specific embodiment
Embodiment 1: a kind of raw marrow symplectic bone agent of the kidney tonifying of accelerating union of bone fracture is made of the bulk pharmaceutical chemicals of following parts by weight: Native copper 45g, rhizome of davallia 12g, teasel 10g, Semen Cuscutae 10g, Schisandra chinensis 10g, radix cyathulae 12g, Radix Salviae Miltiorrhizae 12g, Caulis Spatholobi 12g, Eupolyphoge sinensis 12g, olibanum 10g, myrrh 10g, safflower 10g, Radix Angelicae Sinensis 10g, Radix Astragali 25g, Radix Paeoniae Alba 12g, rhizoma alismatis 10g, Herba Lycopi 10g, Radix Angelicae Pubescentis 10g, Rhizoma Chuanxiong 10g, Radix Glycyrrhizae 8g are decocted in water for oral dose.
Embodiment 2: a kind of raw marrow symplectic bone agent of the kidney tonifying of accelerating union of bone fracture is made of the bulk pharmaceutical chemicals of following parts by weight: Native copper 50g, rhizome of davallia 15g, teasel 12g, Semen Cuscutae 12g, Schisandra chinensis 12g, radix cyathulae 15g, Radix Salviae Miltiorrhizae 15g, Caulis Spatholobi 15g, Eupolyphoge sinensis 15g, olibanum 12g, myrrh 12g, safflower 12g, Radix Angelicae Sinensis 12g, Radix Astragali 30g, Radix Paeoniae Alba 15g, rhizoma alismatis 12g, Herba Lycopi 12g, Radix Angelicae Pubescentis 12g, Rhizoma Chuanxiong 12g, Radix Glycyrrhizae 9g are decocted in water for oral dose.
Embodiment 3: a kind of raw marrow symplectic bone agent of the kidney tonifying of accelerating union of bone fracture is made of the bulk pharmaceutical chemicals of following parts by weight: Native copper 55g, rhizome of davallia 18g, teasel 15g, Semen Cuscutae 15g, Schisandra chinensis 15g, radix cyathulae 18g, Radix Salviae Miltiorrhizae 18g, Caulis Spatholobi 18g, Eupolyphoge sinensis 18g, olibanum 15g, myrrh 15g, safflower 15g, Radix Angelicae Sinensis 15g, Radix Astragali 35g, Radix Paeoniae Alba 18g, rhizoma alismatis 15g, Herba Lycopi 15g, Radix Angelicae Pubescentis 15g, Rhizoma Chuanxiong 15g, Radix Glycyrrhizae 10g are decocted in water for oral dose.
For the clinical efficacy and safety for further investigating above-described embodiment drug, we have selected the disease of 800 fracture Example carries out clinical test to the treatment curative effect of drug of the present invention.
The patient that 800 are fractured is randomly divided into four groups, every group 200.In control group, male 100, women 100; 20 years old or less 15,21~35 years old 65,36~50 years old 70,51 years old or more 50;In treatment group 1, male 100, women 100;20 years old or less 14,21~35 years old 63,36~50 years old 71,51 years old or more 52;In treatment group 2, male 105 Example, women 95;20 years old or less 15,21~35 years old 64,36~50 years old 69,51 years old or more 52;In treatment group 3, male Property 100, women 100;20 years old or less 14,21~35 years old 62,36~50 years old 70,51 years old or more 54.
Four groups of cases are comparable in terms of sex, age, course of disease, etc. through statistical analysis.
Control group is treated using the drug of common oral accelerating union of bone fracture;1 institute of the present embodiment is taken orally in treatment group 1 Drug obtained;Drug obtained by the present embodiment 2 is taken orally in treatment group 2;Drug obtained by the present embodiment 3 is taken orally in treatment group 3, Three groups for the treatment of groups are all daily early, late each one, 7 days as one therapeutic courses, are spaced 2-3 days, continuously take the 2-3 course for the treatment of.
Criterion of therapeutical effect: cure: union is complete, heading line off of fracturing;Effective: fracture end has apparent poroma to be formed, bone Broken line is fuzzy;Effective: fracture end has apparent poroma to be formed, and fracture gap narrows, activity without exception;Invalid: fracture end is without bright Aobvious poroma is formed, and fracture line is high-visible, is had no difference to that before treatment.Curative effect comparision result such as table after four groups of case treatments One.
Table one
Group Number of cases It cures n (%) Effective n (%) Effective n (%) Invalid n (%)
Control group 200 154(77) 162(81) 175(87.5) 25(12.5)
Treatment group 1 200 177(88.5) 187(93.5) 191(95.5) 9(4.5)
Treatment group 2 200 178(89) 188(94) 192(96) 8(4)
Treatment group 3 200 177(88.5) 187(93.5) 191(95.5) 9(4.5)
Pass through above-mentioned control, it can be seen that using Chinese medicine of the present invention treatment fracture, therapeutic effect is significant, with conventional oral medicine Object is compared, and cure rate is high.
The present invention has good curative effect to accelerating union of bone fracture, and has no toxic side effect, and does not develop drug resistance, and treats for one within 7 days Journey after taking a course for the treatment of, is spaced 2-3 days, is further continued for taking next course for the treatment of, continuously take the 2-3 course for the treatment of, is applied with 1~3 It can be cured after the course for the treatment of, cure rate is efficient up to 95.5% up to 88.5% or more.
It is as follows that some patientss cure case:
Field, male, 28 years old, fracture of tibia, after taking 2 courses for the treatment of of drug obtained by the present embodiment 1, patient symptom disappeared It loses, recovery from illness.
Certain is shut out, female, 39 years old, fracture of head of femur, after taking 3 courses for the treatment of of drug obtained by the present embodiment 2, patient symptom disappeared It loses, recovery from illness.
Poplar, male, 41 years old, fracture of nasal bone, after taking 1 course for the treatment of of drug obtained by the present embodiment 3, patient symptom disappeared It loses, recovery from illness.
Mr. Luo, male, 18 years old, comminuted fracture of patella, after taking 3 courses for the treatment of of drug obtained by the present embodiment 2, patient's disease Shape disappears, recovery from illness.

Claims (1)

1. a kind of raw marrow symplectic bone agent of the kidney tonifying of accelerating union of bone fracture, it is characterised in that: be made of the bulk pharmaceutical chemicals of following parts by weight: Native copper 50g, rhizome of davallia 15g, teasel 12g, Semen Cuscutae 12g, Schisandra chinensis 12g, radix cyathulae 15g, Radix Salviae Miltiorrhizae 15g, Caulis Spatholobi 15g, Eupolyphoge sinensis 15g, olibanum 12g, myrrh 12g, safflower 12g, Radix Angelicae Sinensis 12g, Radix Astragali 30g, Radix Paeoniae Alba 15g, rhizoma alismatis 12g, Herba Lycopi 12g, Radix Angelicae Pubescentis 12g, Rhizoma Chuanxiong 12g, Radix Glycyrrhizae 9g are decocted in water for oral dose.
CN201510167338.0A 2015-04-02 2015-04-02 A kind of raw marrow symplectic bone agent of kidney tonifying Expired - Fee Related CN104800443B (en)

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CN105412462A (en) * 2015-12-18 2016-03-23 东阳市人民医院 Bone setting granules and production method thereof
CN105998439A (en) * 2016-07-15 2016-10-12 王士杰 Symplectic bone medicine and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101623415A (en) * 2009-08-07 2010-01-13 葛超顺 Traditional Chinese medicine preparation for treating fractures and bone injuries
CN102579605A (en) * 2012-03-12 2012-07-18 高永学 Oral Chinese medicinal composition for treating bone fracture diseases
CN103877556A (en) * 2014-04-17 2014-06-25 崔贵成 Traditional Chinese medicine plaster for bone injury and fracture

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101623415A (en) * 2009-08-07 2010-01-13 葛超顺 Traditional Chinese medicine preparation for treating fractures and bone injuries
CN102579605A (en) * 2012-03-12 2012-07-18 高永学 Oral Chinese medicinal composition for treating bone fracture diseases
CN103877556A (en) * 2014-04-17 2014-06-25 崔贵成 Traditional Chinese medicine plaster for bone injury and fracture

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