CN104784614A - Traditional Chinese medicine composition for treating kidney deficiency - Google Patents
Traditional Chinese medicine composition for treating kidney deficiency Download PDFInfo
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- CN104784614A CN104784614A CN201510135676.6A CN201510135676A CN104784614A CN 104784614 A CN104784614 A CN 104784614A CN 201510135676 A CN201510135676 A CN 201510135676A CN 104784614 A CN104784614 A CN 104784614A
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Abstract
The invention discloses a traditional Chinese medicine composition for treating kidney deficiency, which comprises the following traditional Chinese medicine raw materials in parts by weight: 10-30 parts of codonopsis pilosula, 10-20 parts of cynanchum bungei decne, 10-30 parts of Chinese yam, 10-30 parts of poria cocos, 10-30 parts of polygala tenuifolia, 10-20 parts of spina date seed, 5-15 parts of radix aucklandiae, 10-20 parts of platycodon grandiflorum, 5-15 parts of tangerine peel, 10-30 parts of rhizoma cimicifugae, 5-15 parts of radix bupleuri, 10-20 parts of Chinese angelica, 10-20 parts of radix ophiopogonis, 10-20 parts of radix rehmanniae recen, 5-15 parts of amoorcorn tree bark, 10-20 parts of fructus amomi, 10-20 parts of tribulus terrestris, 5-15 parts of gardenia and 5-15 parts of liquorice. The traditional Chinese medicine composition has effects of nourishing liver, strengthening spleen, tonifying kidney, supporting yang, securing essence, replenishing marrow, nourishing blood and promoting the production of body fluid, and has a significant curative effect and a reliable effect on treating the kidney deficiency.
Description
Technical field
The present invention relates to a kind of medicinal preparation not determining structure of traditional herbal medicines, the Chinese medicine composition that especially a kind for the treatment of is suffered from a deficiency of the kidney.
Background technology
Suffer from a deficiency of the kidney and refer to that kidney vital essence negative and positive are not enough." suffering from a deficiency of the kidney " is a wide in range concept, and he comprises the relevant disease of all multisystems such as urinary system, reproductive system, endocrine metabolism system, neuropsychiatric and digestion, blood, breathing.The symptom of suffering from a deficiency of the kidney is a lot, dizzy unable, insomnia and dreamful sleep, and hypomnesis is deficient in energy, irritability, irritated, anxiety, and depressed, libido reduces, impotence in male, premature ejaculation, woman's uterine hypoplasia, and menoxenia is infertile etc.The symptom of suffering from a deficiency of the kidney shows as in urinary system: frequent micturition, and urine is waited for, the symptoms such as clear urine in large amounts.At present, it is varied market to be treated the Chinese Traditional Medicines of suffering from a deficiency of the kidney, but there is the deficiency that the course for the treatment of is long, curative effect is undesirable.
The traditional Chinese medical science is thought, if overstrain lust is excessive, or prolonged illness is lost foster, and consumption hinders vital essence, then there will be performance of suffering from a deficiency of the kidney.
According to theory of Chinese medical science, for the pathogeny of suffering from a deficiency of the kidney, with nourishing the liver spleen invigorating, tonifying the kidney to consolidate the essence for the rule for the treatment of, carry out dialectical composition of prescription, to reach the object for the treatment of both the principal and secondary aspects of a disease.
Summary of the invention
There is to overcome in prior art medicine of suffering from a deficiency of the kidney the deficiency that the course for the treatment of is long, curative effect is undesirable, the invention provides a kind ofly to prepare conveniently, medicine source is wide, cost is low, evident in efficacy, reliable effect, the treatment that has no side effect are suffered from a deficiency of the kidney Chinese medicine composition.
The technical solution adopted for the present invention to solve the technical problems is: the Chinese medicine composition that a kind for the treatment of is suffered from a deficiency of the kidney, it is characterized in that: its raw material of Chinese medicine and weight are: Radix Codonopsis 10-30 part, Radix cynanchi wilfordii 10-20 part, Rhizoma Dioscoreae 10-30 part, Poria 10-30 part, Radix Polygalae 10-30 part, Semen Ziziphi Spinosae 10-20 part, Radix Aucklandiae 5-15 part, Radix Platycodonis 10-20 part, Pericarpium Citri Reticulatae 5-15 part, Rhizoma Cimicifugae 10-30 part, Radix Bupleuri 5-15 part, Radix Angelicae Sinensis 10-20 part, Radix Ophiopogonis 10-20 part, Radix Rehmanniae 10-20 part, Cortex Phellodendri 5-15 part, Fructus Amomi 10-20 part, Fructus Tribuli 10-20 part, Fructus Gardeniae 5-15 part, Radix Glycyrrhizae 5-15 part.
The preferred technical solution of the present invention is: the Chinese medicine composition that a kind for the treatment of is suffered from a deficiency of the kidney, and it is characterized in that: its raw material of Chinese medicine and weight are: Radix Codonopsis 20 parts, Radix cynanchi wilfordii 15 parts, Rhizoma Dioscoreae 20 parts, 20 parts, Poria, Radix Polygalae 20 parts, Semen Ziziphi Spinosae 15 parts, the Radix Aucklandiae 10 parts, Radix Platycodonis 15 parts, Pericarpium Citri Reticulatae 10 parts, Rhizoma Cimicifugae 20 parts, Radix Bupleuri 10 parts, Radix Angelicae Sinensis 15 parts, Radix Ophiopogonis 15 parts, Radix Rehmanniae 15 parts, Cortex Phellodendri 10 parts, Fructus Amomi 15 parts, Fructus Tribuli 15 parts, Fructus Gardeniae 10 parts, 10 parts, Radix Glycyrrhizae.
Chinese medicine composition of the present invention is under Traditional Chinese medical theory and clinical experience instruct, selected medicament composing prescription.In Chinese medicine composition of the present invention: Radix Codonopsis has effect of invigorating the spleen and replenishing QI, spleen invigorating lung benefiting; Radix cynanchi wilfordii has effect of liver and kidney tonifying, bone and muscle strengthening; Rhizoma Dioscoreae has strengthening the spleen and tonifying the lung, stomach reinforcing the kidney invigorating, benefit of reinforcing the kidney essence, hearing-improing and eyesight improving, help the five internal organs, bone and muscle strengthening, long will are calmed the nerves, effect of life lengthening; Poria has effect of promoting diuresis to eliminate damp pathogen, strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming; Radix Polygalae has Fructus Alpiniae Oxyphyllae of calming the nerves, it is relieving convulsion to eliminate the phlegm, strongly fragrant effect is fallen apart in circulation of qi promoting; Semen Ziziphi Spinosae has effect of nourishing the liver arresting sweating, mind tranquilizing and the heart calming; The Radix Aucklandiae has effect of intestinal stasis relieving in promoting the circulation of QI to relieve pain, tune; Radix Platycodonis has lung qi dispersing and eliminates the phlegm, fosters the spirit of nobility and enrich blood, sharp the five internal organs, mend effect of five kinds of over strain; Pericarpium Citri Reticulatae has effect of diuretic, drying dampness to eliminate phlegm in regulating qi-flowing for strengthening spleen, tune; Rhizoma Cimicifugae has the effect delivering rash, heat-clearing and toxic substances removing, elevate a turnable ladder yang-energy; Radix Bupleuri have evacuate bring down a fever, effect of yang invigorating soothing liver-QI; Radix Angelicae Sinensis have enrich blood invigorate blood circulation, effect of menstruction regulating and pain relieving, loosening bowel to relieve constipation; There is Radix Ophiopogonis YIN nourishing and the production of body fluid promoting, effect that lung moistening clears away heart-fire; Radix Rehmanniae has heat clearing away, YIN nourishing of promoting the production of body fluid, effect of nourishing blood; Effect that Cortex Phellodendri has heat clearing and damp drying, pathogenic fire purging removes steaming, detoxification sore treatment; Fructus Amomi has removing dampness appetizing, warming spleen and stopping diarrha, antiabortive effect of regulating the flow of vital energy; Fructus Tribuli has effect of dispersing the stagnated live-QI to relieve the stagnation of QI, dispelling pathogenic wind for improving eyesight; Fructus Gardeniae has effect of pathogenic fire purging relieving restlessness, clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body; Radix Glycyrrhizae has effect of invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, coordinating the actions of various ingredients in a prescription.Drug component in the present composition, through dialectical compatibility, complements each other using, has synergism, plays nourishing the liver spleen invigorating altogether, effect that reinforcing the kidney and supporting YANG, controlling nocturnal emission with astringent drugs mend marrow, nourishing blood to promote the production of body fluid, reaches the object for the treatment of both the principal and secondary aspects of a disease to suffering from a deficiency of the kidney.
The component of the present composition all adopts natural raw material of Chinese medicine, and its preparation is easy, medicine source is wide, cost is low.It follows the prescriptions principle of the traditional Chinese medical science, and various component drug adopts the use that is decocted in water for oral dose.Through clinical practice checking, it is evident in efficacy, reliable effect, mild in medicine property and, do not occur toxic and side effects, total effective rate 94.3%, cure rate reaches 72.8%.
Detailed description of the invention
Below in conjunction with embodiment, the present invention will be further described.
Embodiment 1
The Chinese medicine composition that treatment is suffered from a deficiency of the kidney, its raw material of Chinese medicine and weight proportion are: Radix Codonopsis 20g, Radix cynanchi wilfordii 15g, Rhizoma Dioscoreae 20g, Poria 20g, Radix Polygalae 20g, Semen Ziziphi Spinosae 15g, Radix Aucklandiae 10g, Radix Platycodonis 15g, Pericarpium Citri Reticulatae 10g, Rhizoma Cimicifugae 20g, Radix Bupleuri 10g, Radix Angelicae Sinensis 15g, Radix Ophiopogonis 15g, Radix Rehmanniae 15g, Cortex Phellodendri 10g, Fructus Amomi 15g, Fructus Tribuli 15g, Fructus Gardeniae 10g, Radix Glycyrrhizae 10g.
Embodiment 2
The Chinese medicine composition that treatment is suffered from a deficiency of the kidney, its raw material of Chinese medicine and weight proportion are: Radix Codonopsis 10g, Radix cynanchi wilfordii 20g, Rhizoma Dioscoreae 10g, Poria 30g, Radix Polygalae 10g, Semen Ziziphi Spinosae 20g, Radix Aucklandiae 5g, Radix Platycodonis 20g, Pericarpium Citri Reticulatae 5g, Rhizoma Cimicifugae 30g, Radix Bupleuri 5g, Radix Angelicae Sinensis 20g, Radix Ophiopogonis 10g, Radix Rehmanniae 20g, Cortex Phellodendri 5g, Fructus Amomi 20g, Fructus Tribuli 10g, Fructus Gardeniae 15g, Radix Glycyrrhizae 5g.
Embodiment 3
The Chinese medicine composition that treatment is suffered from a deficiency of the kidney, its raw material of Chinese medicine and weight proportion are: Radix Codonopsis 30g, Radix cynanchi wilfordii 10g, Rhizoma Dioscoreae 30g, Poria 10g, Radix Polygalae 30g, Semen Ziziphi Spinosae 10g, Radix Aucklandiae 15g, Radix Platycodonis 10g, Pericarpium Citri Reticulatae 15g, Rhizoma Cimicifugae 10g, Radix Bupleuri 15g, Radix Angelicae Sinensis 10g, Radix Ophiopogonis 20g, Radix Rehmanniae 10g, Cortex Phellodendri 15g, Fructus Amomi 10g, Fructus Tribuli 20g, Fructus Gardeniae 5g, Radix Glycyrrhizae 15g.
Embodiment 4
The Chinese medicine composition that treatment is suffered from a deficiency of the kidney, its raw material of Chinese medicine and weight proportion are: Radix Codonopsis 15g, Radix cynanchi wilfordii 18g, Rhizoma Dioscoreae 15g, Poria 25g, Radix Polygalae 15g, Semen Ziziphi Spinosae 18g, Radix Aucklandiae 8g, Radix Platycodonis 18g, Pericarpium Citri Reticulatae 8g, Rhizoma Cimicifugae 25g, Radix Bupleuri 8g, Radix Angelicae Sinensis 18g, Radix Ophiopogonis 12g, Radix Rehmanniae 18g, Cortex Phellodendri 8g, Fructus Amomi 18g, Fructus Tribuli 12g, Fructus Gardeniae 13g, Radix Glycyrrhizae 8g.
Embodiment 5
The Chinese medicine composition that treatment is suffered from a deficiency of the kidney, its raw material of Chinese medicine and weight proportion are: Radix Codonopsis 25g, Radix cynanchi wilfordii 12g, Rhizoma Dioscoreae 25g, Poria 15g, Radix Polygalae 25g, Semen Ziziphi Spinosae 12g, Radix Aucklandiae 13g, Radix Platycodonis 12g, Pericarpium Citri Reticulatae 13g, Rhizoma Cimicifugae 15g, Radix Bupleuri 13g, Radix Angelicae Sinensis 12g, Radix Ophiopogonis 18g, Radix Rehmanniae 12g, Cortex Phellodendri 13g, Fructus Amomi 12g, Fructus Tribuli 18g, Fructus Gardeniae 8g, Radix Glycyrrhizae 13g.
Chinese medicine composition in embodiment of the present invention decocting method routinely produces medicament.Concrete grammar is as follows: the raw material of Chinese medicine of prescription is put into container, adds cold water and covers powder, soaks 15 ~ 20 minutes, then adds water and do not have powder about 6 centimetres, carries out first time to decoct, and adopts intense fire to decoct, with slow fire boiling 20 ~ 30 minutes after boiling at a simmer; Second time decocts, and adds water and does not have powder about 6 centimetres, decocts 15 ~ 20 minutes after water boils.Twice decoction is removed slag extracting juice, merges.
The Chinese medicine composition that the present invention suffers from a deficiency of the kidney with a kind for the treatment of given by embodiment 1, does clinical efficacy and is summarized as follows:
One, general data: Chinese medicine composition of the present invention is applied to clinical observation case 70 example, wherein man 40 example, female 30 example, 20 ~ 70 years old age.The shortest person of the course of disease 3 months, most elder reaches 3 years, average 1 year.
Two, diagnostic criteria:
1, ache of the spinal column (except traumatic);
2, soreness of waist and knee or talalgia;
3, tinnitus or deafness;
4, loss of hairs or luxated tooth;
5, the heeltap or incontinence is had after urine;
6, sexual hypofunction, infertile, sterile.
Three, usage and dosage: during clinical practice, one day potion, decocting twice extracting juice is about 300ml, and point early, late twice half an hour ante cibum warmly take.It within five days, is a course for the treatment of.
Four, criterion of therapeutical effect:
(1) cure: symptom disappears completely, nothing repeatedly;
(2) take a turn for the better: symptom is obviously alleviated, simultaneous phenomenon disappears substantially or large portion alleviates, and meets influence factor without increasing the weight of;
(3) do not heal: all symptoms increase the weight of trend without alleviating or having.
Five, therapeutic effect: in this clinical observation case, takes medicine 2-10 the course for the treatment of, cures 51 examples, and take a turn for the better 15 examples, and do not heal 4 examples.There is not toxic and side effects in treatments period.
Six, model case:
Case 1: the Qin, female, 46 years old.Patient's readme: dizzy unable, soreness of the waist and knees, insomnia and dreamful sleep, lethargy, nocturia, sore waist and aching in the waist and the back before menstruation, lower abdomen drops.Examine and see: pale tongue with white fur, deep-slow pulse, chi is unable.Take 1 course for the treatment of of medicament prepared by Chinese medicine composition of the present invention, dizzy, unable, insomnia, nocturia is eased; Continue to take 2 courses for the treatment of, the moon, premenstrual malaise symptoms disappeared, and followed up a case by regular visits to and did not recur half a year.
Case 2: Zhao, man, 32 years old.Patient's extremity are swollen and are felt cold, sore waist and aching in the waist and the back, dizzy unable, insomnia and dreamful sleep, and frequent micturition, libido reduces.Take 2 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, the soreness of waist, cold extremities symptom alleviate; Continue to take 2 courses for the treatment of, symptom, sign disappear completely, cure.Follow up a case by regular visits to and do not recur half a year.
Claims (2)
1. a treatment Chinese medicine composition of suffering from a deficiency of the kidney, is characterized in that: its raw material of Chinese medicine and weight are: Radix Codonopsis 10-30 part, Radix cynanchi wilfordii 10-20 part, Rhizoma Dioscoreae 10-30 part, Poria 10-30 part, Radix Polygalae 10-30 part, Semen Ziziphi Spinosae 10-20 part, Radix Aucklandiae 5-15 part, Radix Platycodonis 10-20 part, Pericarpium Citri Reticulatae 5-15 part, Rhizoma Cimicifugae 10-30 part, Radix Bupleuri 5-15 part, Radix Angelicae Sinensis 10-20 part, Radix Ophiopogonis 10-20 part, Radix Rehmanniae 10-20 part, Cortex Phellodendri 5-15 part, Fructus Amomi 10-20 part, Fructus Tribuli 10-20 part, Fructus Gardeniae 5-15 part, Radix Glycyrrhizae 5-15 part.
2. a kind for the treatment of according to claim 1 Chinese medicine composition of suffering from a deficiency of the kidney, is characterized in that: its raw material of Chinese medicine and weight are: Radix Codonopsis 20 parts, Radix cynanchi wilfordii 15 parts, Rhizoma Dioscoreae 20 parts, 20 parts, Poria, Radix Polygalae 20 parts, Semen Ziziphi Spinosae 15 parts, the Radix Aucklandiae 10 parts, Radix Platycodonis 15 parts, Pericarpium Citri Reticulatae 10 parts, Rhizoma Cimicifugae 20 parts, Radix Bupleuri 10 parts, Radix Angelicae Sinensis 15 parts, Radix Ophiopogonis 15 parts, Radix Rehmanniae 15 parts, Cortex Phellodendri 10 parts, Fructus Amomi 15 parts, Fructus Tribuli 15 parts, Fructus Gardeniae 10 parts, 10 parts, Radix Glycyrrhizae.
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| CN201510135676.6A CN104784614A (en) | 2015-03-26 | 2015-03-26 | Traditional Chinese medicine composition for treating kidney deficiency |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106110014A (en) * | 2016-07-21 | 2016-11-16 | 启东兴都水产品有限公司 | The Chinese medicine composition that a kind for the treatment of is suffered from a deficiency of the kidney |
| CN106929356A (en) * | 2017-03-22 | 2017-07-07 | 朱纪隆 | Nourishing liver and kidney wine of rice fermented with red yeast and preparation method thereof |
| CN107080804A (en) * | 2017-03-22 | 2017-08-22 | 余君豪 | A kind of Chinese medicine composition for treating syndrome of cold-dampness due to kidney deficiency |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103800838A (en) * | 2014-02-20 | 2014-05-21 | 柳晖 | Traditional Chinese medicine composition for treating deficiency of the kidney-yin |
-
2015
- 2015-03-26 CN CN201510135676.6A patent/CN104784614A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103800838A (en) * | 2014-02-20 | 2014-05-21 | 柳晖 | Traditional Chinese medicine composition for treating deficiency of the kidney-yin |
Non-Patent Citations (3)
| Title |
|---|
| 刘新瑞: ""补肾益疾案"临床分析", 《中国中医急症》 * |
| 曹开镛: "中医男科证治纵横", 《辽宁中医杂志》 * |
| 程士德: "五脏虚证的辨证治疗（续二）", 《中国农村医书》 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106110014A (en) * | 2016-07-21 | 2016-11-16 | 启东兴都水产品有限公司 | The Chinese medicine composition that a kind for the treatment of is suffered from a deficiency of the kidney |
| CN106929356A (en) * | 2017-03-22 | 2017-07-07 | 朱纪隆 | Nourishing liver and kidney wine of rice fermented with red yeast and preparation method thereof |
| CN107080804A (en) * | 2017-03-22 | 2017-08-22 | 余君豪 | A kind of Chinese medicine composition for treating syndrome of cold-dampness due to kidney deficiency |
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Application publication date: 20150722 |