CN104784266A - Agent for treating perianal abscess - Google Patents
Agent for treating perianal abscess Download PDFInfo
- Publication number
- CN104784266A CN104784266A CN201510210275.2A CN201510210275A CN104784266A CN 104784266 A CN104784266 A CN 104784266A CN 201510210275 A CN201510210275 A CN 201510210275A CN 104784266 A CN104784266 A CN 104784266A
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- parts
- radix
- agent
- perianal abscess
- medicament
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- 206010048946 Anal abscess Diseases 0.000 title claims abstract description 15
- 239000000463 material Substances 0.000 claims abstract description 6
- 239000003814 drug Substances 0.000 claims description 20
- 238000011282 treatment Methods 0.000 claims description 11
- 241000549954 Gymnema yunnanense Species 0.000 claims description 6
- 241001316533 Impatiens leptocaulon Species 0.000 claims description 6
- 244000292697 Polygonum aviculare Species 0.000 claims description 6
- 235000006386 Polygonum aviculare Nutrition 0.000 claims description 6
- 244000025254 Cannabis sativa Species 0.000 claims description 5
- 239000006210 lotion Substances 0.000 claims description 5
- 239000000203 mixture Substances 0.000 claims description 4
- 239000002775 capsule Substances 0.000 claims description 2
- 239000007919 dispersible tablet Substances 0.000 claims description 2
- 238000002360 preparation method Methods 0.000 claims description 2
- 239000003826 tablet Substances 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 4
- 244000159188 Antidesma dallachyanum Species 0.000 abstract 1
- 235000015873 Antidesma dallachyanum Nutrition 0.000 abstract 1
- 241000208327 Apocynaceae Species 0.000 abstract 1
- 241001252546 Doellingeria Species 0.000 abstract 1
- 241000576409 Ligustrum sinense Species 0.000 abstract 1
- 244000260581 Pentapetes phoenicea Species 0.000 abstract 1
- 244000245600 Persicaria longiseta Species 0.000 abstract 1
- 240000002800 Sanicula europaea Species 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 description 9
- 208000033809 Suppuration Diseases 0.000 description 4
- 230000036772 blood pressure Effects 0.000 description 4
- 206010000269 abscess Diseases 0.000 description 3
- 229940079593 drug Drugs 0.000 description 3
- 210000000664 rectum Anatomy 0.000 description 3
- 206010047700 Vomiting Diseases 0.000 description 2
- 206010052428 Wound Diseases 0.000 description 2
- 208000027418 Wounds and injury Diseases 0.000 description 2
- 208000002173 dizziness Diseases 0.000 description 2
- 206010025482 malaise Diseases 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 230000000630 rising effect Effects 0.000 description 2
- 230000000638 stimulation Effects 0.000 description 2
- 231100000331 toxic Toxicity 0.000 description 2
- 230000002588 toxic effect Effects 0.000 description 2
- 206010000060 Abdominal distension Diseases 0.000 description 1
- 208000016583 Anus disease Diseases 0.000 description 1
- 206010010774 Constipation Diseases 0.000 description 1
- 241000721047 Danaus plexippus Species 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 208000004680 Rectal Fistula Diseases 0.000 description 1
- 206010057071 Rectal tenesmus Diseases 0.000 description 1
- 206010038743 Restlessness Diseases 0.000 description 1
- 208000001871 Tachycardia Diseases 0.000 description 1
- 206010053692 Wound complication Diseases 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 239000002671 adjuvant Substances 0.000 description 1
- 210000002255 anal canal Anatomy 0.000 description 1
- 206010002156 anal fistula Diseases 0.000 description 1
- 230000004596 appetite loss Effects 0.000 description 1
- 206010003119 arrhythmia Diseases 0.000 description 1
- 230000006793 arrhythmia Effects 0.000 description 1
- 230000036760 body temperature Effects 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000035487 diastolic blood pressure Effects 0.000 description 1
- 230000008034 disappearance Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 210000003608 fece Anatomy 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 208000028774 intestinal disease Diseases 0.000 description 1
- 210000000265 leukocyte Anatomy 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 235000021266 loss of appetite Nutrition 0.000 description 1
- 208000019017 loss of appetite Diseases 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 210000000440 neutrophil Anatomy 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 239000008194 pharmaceutical composition Substances 0.000 description 1
- 230000002980 postoperative effect Effects 0.000 description 1
- 208000009146 rhinoscleroma Diseases 0.000 description 1
- 210000004872 soft tissue Anatomy 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 231100000057 systemic toxicity Toxicity 0.000 description 1
- 230000035488 systolic blood pressure Effects 0.000 description 1
- 230000006794 tachycardia Effects 0.000 description 1
- 208000012271 tenesmus Diseases 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 230000029663 wound healing Effects 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to an agent for treating perianal abscess. The agent is prepared from the following substances in parts by weight: 120 parts of subacaulis lipsch, 100 parts of polygonum blumei meisn, 100 parts of phoenix-tail fern, 80 parts of antidesma bunius, 60 parts of pentapetes phoenicea, 50 parts of Szechwan-Yunnan sanicle root, 70 parts of asclepiadaceae, 50 parts of nitid Chinese privet bark and leaf, 30 parts of scabrous doellingeria rhizome and root and 20 parts of omeiana. All the components of the agent for treating perianal abscess disclosed by the invention are natural materials, the agent is high in safety and exact in curative effect and is suitable for large-scale clinical popularization.
Description
Technical field
The present invention relates to field of medicaments, relate in particular to a kind of medicament for the treatment of perianal abscess.
Background technology
Perianal abscess refers in anal canal, rectum surrounding soft tissue or its peripheral clearance generation acute festering type infects the rear abscess formed, and sickness rate accounts for 8% ~ 25% of anal and intestinal disease, occupies anorectal surgical the 2nd.Domestic clinical research data display, perianal abscess Post operation wound pain is one of modal complication, main large with postoperative wound surface, open drainage, local nerve enrich, inflammatory reaction, sphincterismus, feces repetitious stimulation, change dressings that it is relevant with psychological factor etc. to stimulate, as dealt with improperly, great misery will be brought to patient, have a strong impact on feed and the sleep of patient, reduce Abwehrkraft des Koepers, finally delay wound healing, reduce therapeutic effect, gerontal patient even can bring out blood pressure rising, tachycardia, arrhythmia etc.Therefore, the pain alleviating perianal abscess Post operation wound surface is extremely important, is also a clinical medicine worker difficult problem urgently to be resolved hurrily.
Summary of the invention
The object of this invention is to provide a kind of medicament for the treatment of perianal abscess.
In order to realize object of the present invention, the invention provides a kind of medicament for the treatment of perianal abscess, it is made up of the material of following weight proportioning: little Radix Scorzonerae austriacae 120 parts, horse knotweed 100 parts, well limit grass 100 parts, Radix seu Folium Antidesmae bunii 80 parts, Herba Portulacae Grandiflorae 60 parts, Radix Saniculae Astrantifoliae 50 parts, Gymnema yunnanense Tsiang 70 parts, Folium Ligustri QuihouiCortex seu Folium Ligustri nitidi 50 parts, Rhizoma et Radix Doellingeriae (Herba Doellingeriae) 30 parts and Impatiens leptocaulon Hook.f. 20 parts.
Preferably, described medicament can be tablet, dispersible tablet, capsule or lotion.
The present invention also provides the purposes of compositions in the medicament of preparation treatment perianal abscess, and described medicament is made up of the material of following weight proportioning: little Radix Scorzonerae austriacae 120 parts, horse knotweed 100 parts, well limit grass 100 parts, Radix seu Folium Antidesmae bunii 80 parts, Herba Portulacae Grandiflorae 60 parts, Radix Saniculae Astrantifoliae 50 parts, Gymnema yunnanense Tsiang 70 parts, Folium Ligustri QuihouiCortex seu Folium Ligustri nitidi 50 parts, Rhizoma et Radix Doellingeriae (Herba Doellingeriae) 30 parts and Impatiens leptocaulon Hook.f. 20 parts.
In the present compositions, little Radix Scorzonerae austriacae is monarch drug, and horse knotweed, Jing Biancao, Radix seu Folium Antidesmae bunii are ministerial drug, and Herba Portulacae Grandiflorae, Radix Saniculae Astrantifoliae, Gymnema yunnanense Tsiang, Folium Ligustri QuihouiCortex seu Folium Ligustri nitidi, Rhizoma et Radix Doellingeriae (Herba Doellingeriae) are adjuvant drug, and Impatiens leptocaulon Hook.f. is for making medicine.
Whole compositions of the medicament for the treatment of perianal abscess of the present invention are all natural materials, and safety is better, and clear curative effect, is suitable for large-scale promotion clinically.
Detailed description of the invention
The present invention is further illustrated below by embodiment.It should be understood that embodiments of the invention are for illustration of the present invention instead of limitation of the present invention.Essence according to the present invention all belongs to the scope of protection of present invention to the simple modifications that the present invention carries out.Unless otherwise stated, the percent in the present invention is percetage by weight.
Embodiment lotion of the present invention
Take little Radix Scorzonerae austriacae 120 grams, horse knotweed 100 grams, well limit grass 100 grams, Radix seu Folium Antidesmae bunii 80 grams, Herba Portulacae Grandiflorae 60 grams, Radix Saniculae Astrantifoliae 50 grams, Gymnema yunnanense Tsiang 70 grams, Folium Ligustri QuihouiCortex seu Folium Ligustri nitidi 50 grams, Rhizoma et Radix Doellingeriae (Herba Doellingeriae) 30 grams and Impatiens leptocaulon Hook.f. 20 grams, add 8500 milliliters, water, heat 5 hours at 90 DEG C in the flask that condensing tube is housed, filter, filtrate is cooled to room temperature, obtains lotion of the present invention.
Experimental example
Diagnostic criteria
Have the infection history of crissum, the symptom often had is: first feel that little lump or lump appear in perianal, the pain increased then, red and swollen heating, falling inflation are uncomfortable, feel restless, night is unable to fall asleep, constipation, urinating freely does not become the rectal distention stimulation symptoms such as tenesmus.And there is the systemic toxicity profiles symptoms such as general malaise, neurolysis are weak, body temperature rising, loss of appetite, the high heat of shiver with cold thereupon.Generally can form abscess at about 1 week, become internal rectum touch can touch softness, tenderness at perianal, have the swollen thing of fluctuation, can pus be extracted out with syringe puncture.If diabrosis or pain relief or disappearance after cutting evacuation of pus voluntarily, temperature decline, systemic conditions takes a turn for the better.Prolongedly not heal, just become anal fistula.Auxiliary examination: have B ultrasonic to survey and pus chamber; Blood leukocytes and neutrophil count increase; Touch: perianal has scleroma or lump, local temperature increases, tenderness or have fluctuation.Be positioned at the abscess of more than levator ani m., digital rectal examination can touch tenderness lump, and internal rectum puncture can extract pus out.
Selector close state diagnostic criteria patient 150 example, wherein man 80 example, female 70 example, the age be 31-48 year, average 37 years old.
Use the lotion prepared in embodiment to treat, every day 3 times, get washing liquid 200 milliliters at every turn, use sterile gauze to dip in wash 3 minutes.Continuous treatment 2 week.
Efficacy assessment standard
Recovery from illness: clinical symptoms disappears completely.
Take a turn for the better: clinical symptoms is improved.
Invalid: clinical symptoms is unchanged or increase the weight of.
Result
Through treatment, find that the clinical symptoms of all patients disappears completely, therefore all meet the efficacy assessment standard of recovery from illness.
Untoward reaction and toxic and side effects monitoring
By detect patient blood pressure, pulse, whether there is Nausea and vomiting, dizzy clinical symptoms judges untoward reaction.Setting human normal systolic pressure is between 90-140mmHg, diastolic pressure is between 60-90mmHg, human normal pulse is 60-100 beat/min, blood pressure, the pulse of patient is measured at treatments period, find that the blood pressure and pulse recorded is all within normal range, the phenomenon not exceeding normal interval occurs, and does not occur Nausea and vomiting, dizzy clinical symptoms.This illustrates that pharmaceutical composition of the present invention does not have obvious untoward reaction, and then proves that this medicine does not have obvious toxic and side effects for human body.
Claims (3)
1. treat the medicament of perianal abscess for one kind, it is characterized in that, it is made up of the material of following weight proportioning: little Radix Scorzonerae austriacae 120 parts, horse knotweed 100 parts, well limit grass 100 parts, Radix seu Folium Antidesmae bunii 80 parts, Herba Portulacae Grandiflorae 60 parts, Radix Saniculae Astrantifoliae 50 parts, Gymnema yunnanense Tsiang 70 parts, Folium Ligustri QuihouiCortex seu Folium Ligustri nitidi 50 parts, Rhizoma et Radix Doellingeriae (Herba Doellingeriae) 30 parts and Impatiens leptocaulon Hook.f. 20 parts.
2. the medicament for the treatment of perianal abscess according to claim 1, is characterized in that, described medicament can be tablet, dispersible tablet, capsule or lotion.
3. the purposes of compositions in the medicament of preparation treatment perianal abscess, it is characterized in that, described medicament is made up of the material of following weight proportioning: little Radix Scorzonerae austriacae 120 parts, horse knotweed 100 parts, well limit grass 100 parts, Radix seu Folium Antidesmae bunii 80 parts, Herba Portulacae Grandiflorae 60 parts, Radix Saniculae Astrantifoliae 50 parts, Gymnema yunnanense Tsiang 70 parts, Folium Ligustri QuihouiCortex seu Folium Ligustri nitidi 50 parts, Rhizoma et Radix Doellingeriae (Herba Doellingeriae) 30 parts and Impatiens leptocaulon Hook.f. 20 parts.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510644269.8A CN105147787A (en) | 2015-04-29 | 2015-04-29 | Medicament for treating perianal abscess |
| CN201510210275.2A CN104784266B (en) | 2015-04-29 | 2015-04-29 | A kind of medicament treating perianal abscess |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510210275.2A CN104784266B (en) | 2015-04-29 | 2015-04-29 | A kind of medicament treating perianal abscess |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510644269.8A Division CN105147787A (en) | 2015-04-29 | 2015-04-29 | Medicament for treating perianal abscess |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104784266A true CN104784266A (en) | 2015-07-22 |
| CN104784266B CN104784266B (en) | 2016-08-17 |
Family
ID=53549764
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510644269.8A Withdrawn CN105147787A (en) | 2015-04-29 | 2015-04-29 | Medicament for treating perianal abscess |
| CN201510210275.2A Expired - Fee Related CN104784266B (en) | 2015-04-29 | 2015-04-29 | A kind of medicament treating perianal abscess |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510644269.8A Withdrawn CN105147787A (en) | 2015-04-29 | 2015-04-29 | Medicament for treating perianal abscess |
Country Status (1)
| Country | Link |
|---|---|
| CN (2) | CN105147787A (en) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103735928A (en) * | 2014-01-02 | 2014-04-23 | 许伟 | Chinese medicinal mixture for treating perianal abscess |
-
2015
- 2015-04-29 CN CN201510644269.8A patent/CN105147787A/en not_active Withdrawn
- 2015-04-29 CN CN201510210275.2A patent/CN104784266B/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103735928A (en) * | 2014-01-02 | 2014-04-23 | 许伟 | Chinese medicinal mixture for treating perianal abscess |
Non-Patent Citations (1)
| Title |
|---|
| 史秀宝: "中西医结合治疗肛周脓肿", 《河南中医》, vol. 20, no. 02, 30 April 2000 (2000-04-30), pages 44 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN104784266B (en) | 2016-08-17 |
| CN105147787A (en) | 2015-12-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| EXSB | Decision made by sipo to initiate substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C41 | Transfer of patent application or patent right or utility model | ||
| CB03 | Change of inventor or designer information |
Inventor after: Zhang Lize Inventor after: Qiao Cuixia Inventor after: Xue Hui Inventor after: Zhao Gang Inventor after: Wang Dandan Inventor after: Liu Penglin Inventor before: Ren Rongyuan |
|
| COR | Change of bibliographic data | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20160704 Address after: 266000 Jiangsu Road, Shandong, China, No. 16, No. Applicant after: Affiliated Hospital of University Of Qingdao Address before: 052165 No. 9 Xingye street, Shijiazhuang economic and Technological Development Zone, Shijiazhuang, Hebei Applicant before: Ren Rongyuan |
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| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20160817 Termination date: 20170429 |
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| CF01 | Termination of patent right due to non-payment of annual fee |