CN104778964A - Detection USB flash disk for disease diagnosis - Google Patents
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- CN104778964A CN104778964A CN201510158057.9A CN201510158057A CN104778964A CN 104778964 A CN104778964 A CN 104778964A CN 201510158057 A CN201510158057 A CN 201510158057A CN 104778964 A CN104778964 A CN 104778964A
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Abstract
The invention discloses a detection USB flash disk for disease diagnosis, comprising a USB flash disk shell, a USB interface, a detection box, a test strip or a tester, a control chip, a circuit board, a test device and a reaction device, wherein the USB interface is inserted at one end of the USB flash disk shell, the control chip is arranged over the circuit board, the detection box is arranged over the control chip, the test device and the reaction device both are arranged in the detection box, the test strip or the tester is inserted or arranged in the detection box, the USB interface, the detection box, the reaction device and the test device are respectively in electrical connection with the control chip, the test strip is electrically connected with the detection box, and the USB flash disk shell is provided with a screen and/or a transparent amplifier electrically connected with the control chip. With the detection USB flash disk for disease diagnosis provided by the invention, up-stream samples can be extracted quickly and simply, cost is relatively low, meanwhile, related steps of latter amplification treatment are reduced, consequently, time for reading result is shortened, and the accuracy rate of detection and diagnosis is high.
Description
Technical field
The present invention relates to a kind of USB flash disk--USB flash drive, is also called flash disk or flash disk.Particularly relate to a kind of detection USB flash disk for medical diagnosis on disease.
Background technology
Recent years, all there is obvious growth in nucleic acid molecules diagnosis market in the market share or diversity.The collection sample extraction grown up based on round pcr, increases and is detected on the self-reacting device system also Development and Production of one.But due to the complicacy of nucleic acid molecules test, preparation of samples, repeatability and reliability remain faced huge challenge.Some large diagnostic companies start to throw huge fund and attempt to utilize microfluid or bioelectronics sensor technology to carry out nucleic acid POCT (the other diagnosis of the bed) platform of development & construction fully integratedization.But these apparatus expensive can only be used in and biochemical anti-probably wait limited universe, be difficult to promote, cannot masses be benefited.
From invention till now, in the existing 30 years history of Clinical practice, some research institutions and enterprise start sight to invest this platform to lateral flow (Lateral Flow) technology represented for classics with pregnant inspection.Attempt build nucleic acid lateral flow (Nucleic Acid Lateral Flow, NALF) platform and apply and in nucleic acid POCT.Current Problems existing remain upstream sample extraction rate slowly, complicated and expense is higher, and amplification below processes many steps, and it is long that result reads the time.
Summary of the invention
The present invention completes to solve deficiency of the prior art, the object of this invention is to provide that a kind of structure is simple, that upstream sample is extracted is quicker, simply, expense relative moderate, amplification process correlation step after simultaneously shortening, and then shorten the time of reading result, the detection USB flash disk for medical diagnosis on disease that diagnosis and detection accuracy rate is high.
A kind of detection USB flash disk for medical diagnosis on disease of the present invention, comprise USB flash disk shell body, USB interface, detect box, test-strips or tester, control chip, circuit board, proving installation and reaction unit, described USB interface is located at described USB flash disk shell body one end and is stretched out described USB flash disk shell body, described circuit board is positioned at the described USB flash disk shell body bottom, described control chip is arranged at described circuit board, described detection carriage is located at above described control chip, described proving installation and described reaction unit are all arranged in described detection box, described test-strips or tester can insert in described detection box from outside to inside or be built in described detection box, described proving installation and described reaction unit lay respectively at described test-strips or the upper and lower both sides of tester, described detection box, reaction unit and described proving installation are electrically connected with control chip respectively, described test-strips or tester can remove being electrically connected with described detection box of formula, USB interface is electrically connected with described control chip, described USB flash disk shell body top surface is provided with screen and/or transparent amplifier, described screen is electrically connected with described control chip and/or data communication is connected.
A kind of detection USB flash disk for medical diagnosis on disease of the present invention can also be:
Described test-strips or tester are the elongate in shape be made up of conductive material, and described test-strips or tester side to opposite side are disposed with discarded object uptake zone, test section, reaction zone and sample extraction district.
Described USB flash disk shell body top is provided with recessed adding mouth, and described detection box top is provided with sample extraction system, and described adding mouth and sample extraction system position are all corresponding with the sample extraction zone position of described test-strips or tester.
Described sample extraction system comprise from top to bottom set gradually sample preparation upper strata, sample preparation lower floor, nucleic acid absorption layer and discarded object adsorbed layer, described sample preparation upper strata is corresponding with described adding mouth position.
The both positive and negative polarity of described USB interface is connected with the both positive and negative polarity of control chip respectively, the both positive and negative polarity of described control chip is connected with described detection box both positive and negative polarity respectively with by test-strips or tester, the both positive and negative polarity of described control chip is connected respectively with the both positive and negative polarity of the both positive and negative polarity of proving installation and reaction unit, and the both positive and negative polarity of described control chip is connected with the both positive and negative polarity of screen respectively.
Described circuit board is also provided with flash chip, and described flash chip is connected with control chip, and described flash chip is electrically connected with screen and/or data communication is connected.
Described proving installation comprises the photosensor, photoelectric sensor and the analog to digital converter that connect successively, and described analog to digital converter is connected with a flash chip, and described photosensor, photoelectric sensor and analog to digital converter are all connected with described control chip.
Described reaction unit comprises well heater, temperature sensor and temperature controller, and described well heater, temperature sensor are all connected with control chip with temperature controller.
Described circuit board corner place is provided with spike, and described detection box tetrapod is erected on described spike, and described control chip is arranged between described circuit board and described detection box, arranges flash chip between described circuit board and described detection box.
Described detection box comprises top lid and bottom box, described proving installation is positioned at described top cover lower surface place, described reaction unit is positioned at box upper surface place, the described end, and described proving installation and described reaction unit are arranged at head and the afterbody of described detection box respectively, staggers setting in both positions.
A kind of detection USB flash disk for medical diagnosis on disease of the present invention, comprise USB flash disk shell body, USB interface, detect box, test-strips or tester, control chip, circuit board, proving installation and reaction unit, described USB interface is located at described USB flash disk shell body one end and is stretched out described USB flash disk shell body, described circuit board is positioned at the described USB flash disk shell body bottom, described control chip is arranged at described circuit board, described detection carriage is located at above described control chip, described proving installation and described reaction unit are all arranged in described detection box, described test-strips or tester can insert in described detection box from outside to inside or be built in described detection box, described proving installation and described reaction unit lay respectively at described test-strips or the upper and lower both sides of tester, described detection box, reaction unit and described proving installation are electrically connected with control chip respectively, described test-strips or tester can remove being electrically connected with described detection box of formula, USB interface is electrically connected with described control chip, described USB flash disk shell body top surface is provided with screen and/or transparent amplifier, described screen is electrically connected with described control chip and/or data communication is connected.Like this, during use, USB interface is inserted computer, be energized in smart mobile phone or separately power supply, USB interface uses as power input, USB interface is connected with control chip powers to control chip, after biological sample to be detected and pre-prepd nucleic acid extracting reagent effect, the sample drop of extraction is added on test-strips or tester, and outside plug type test-strips or tester insert in detection box from outside to inside, control chip and the connection detecting box is connected by it, or under the setting of built-in test-strips or tester, the sample extracted directly drops on test-strips or tester, start test-strips or tester effect, test-strips or tester startup control chip are communicated with detection box simultaneously, control chip controls to detect box and runs, reaction unit starts reaction heating test-strips or tester, nucleic acid is made to carry out isothermal duplication within the extremely short time, and discharge fluorescence, proving installation detects fluorescence and is passed through by light signal and is converted into digital signal, be presented on screen, also can be simultaneously direct human eye in some cases by the change of the outward appearance in transparent amplifier observation test bar or tester or color, by the data of screen display or the observation of transparent amplifier, because strong and weak the having that it's too late how much proportional content is with nucleic acid to be detected in sample of signal.Thus judge the presence or absence (positive or negative) of cause of disease to be checked in institute's test sample product and quantize size.Therefore, can carry out whether ill and ill degree judges, namely complete the diagnosis of disease.Certainly, can extract USB flash disk after using, after power-off, all devices and system are all in off-position.Like this, reaction unit expands for accelerating to increase, proving installation is used for detection, then inverted signal data are transmitted, and control chip is used for the overall operation controlling each parts, test-strips and tester are used for detecting break-make while that biological sample reacting with band and detect the connection of box and control chip, and USB interface is used for power supply input power supply.Sample extraction can be made so simple more fast, and expense is cheaper, shortens amplification process subsequent step, greatly shorten the time of reading result, diagnose as early as possible and whether suffer from disease and ill degree, benefit masses, reusability is high, good reliability, accuracy of judgement.That structure is simple, that upstream sample is extracted is more quick relative to the advantage of prior art, simply, expense relative moderate, amplification process correlation step after simultaneously shortening, and then shorten the time of reading result, save cost, judge fast.
Accompanying drawing explanation
The detection USB flash disk embodiment test-strips that Fig. 1 the present invention is used for medical diagnosis on disease inserts schematic diagram.
Fig. 2 the present invention is used for the detection USB flash disk embodiment skeleton view of medical diagnosis on disease.
Fig. 3 the present invention is used for the detection USB flash disk embodiment connection diagram of medical diagnosis on disease.
The detection USB flash disk embodiment that Fig. 4 the present invention is used for medical diagnosis on disease splits schematic diagram.
The detection USB flash disk embodiment that Fig. 5 the present invention is used for medical diagnosis on disease detects box broken away view.
Fig. 6 the present invention is used for the detection USB flash disk embodiment test-strips schematic diagram of medical diagnosis on disease.
Fig. 7 the present invention is used for the detection USB flash disk embodiment outside drawing of medical diagnosis on disease.
Fig. 8 the present invention is used for another embodiment outside drawing of detection USB flash disk of medical diagnosis on disease.
Figure number explanation
1 ... the outer upper cover 2 of USB flash disk ... the outer lower cover 3 of USB flash disk ... USB interface
4 ... detect box 5 ... test-strips or tester (prod) 6 ... control chip
7 ... circuit board 8 ... proving installation 9 ... reaction unit
10 ... discarded object uptake zone 11 ... test section 12 ... reaction zone
13 ... sample extraction district 14 ... filtrating area 15 ... staff is by holding place
16 ... adding mouth 17 ... sample extraction system 18 ... sample preparation upper strata
19 ... sample preparation lower floor 20 ... nucleic acid absorption layer 21 ... discarded object adsorbed layer
22 ... screen 23 ... amplifier 24 ... flash chip
25 ... photosensor 26 ... photoelectric sensor 27 ... analog to digital converter
28 ... temperature controller 29 ... temperature sensor 30 ... well heater
31 ... collet 32 ... renovate 33 ... discarded object absorption cell
Embodiment
Fig. 1 to Fig. 8 below in conjunction with accompanying drawing is described in further detail a kind of detection USB flash disk for medical diagnosis on disease of the present invention.
A kind of detection USB flash disk for medical diagnosis on disease of the present invention, please refer to Fig. 1 to Fig. 8, comprise USB flash disk shell body, USB interface 3, detect box 4, test-strips or tester 5, control chip 6, circuit board 7, proving installation 8 and reaction unit 9, described USB interface 3 is located at described USB flash disk shell body one end and is stretched out described USB flash disk shell body, described circuit board 7 is positioned at the described USB flash disk shell body bottom, described control chip 6 is arranged at above described circuit board 7, described detection box 4 is set up in above described control chip 6, described proving installation 8 and described reaction unit 9 are all arranged in described detection box 4, described test-strips or tester 5 can insert in described detection box 4 from outside to inside or be built in described detection box 4, described proving installation 8 and described reaction unit 9 lay respectively at described test-strips or tester about 5 both sides, described detection box 4, reaction unit 9 and described proving installation 8 are electrically connected with control chip 6 respectively, described test-strips or tester 5 can remove being electrically connected with described detection box 4 of formula, USB interface 3 is electrically connected with described control chip 6, described USB flash disk shell body top surface is provided with screen 22 and/or transparent amplifier 23, described screen 22 is electrically connected with described control chip 6 and/or data communication is connected.Like this, during use, USB interface 3 is inserted computer, be energized in smart mobile phone or separately power supply, USB interface 3 uses as power input, USB interface 3 is connected with control chip 6 powers to control chip 6, after biological sample to be detected and pre-prepd nucleic acid extracting reagent effect, the sample drop of extraction is added on test-strips or tester 5, and outside plug type test-strips or tester 5 insert in detection box 4 from outside to inside, control chip 6 and the connection detecting box 4 is connected by it, or under the setting of built-in test-strips or tester 5, the sample extracted directly drops on test-strips or tester 5, startup test-strips or tester 5 act on, simultaneously test-strips or tester 5 start control chip 6 and detect box 4 and be communicated with, control chip 6 controls to detect box 4 and runs, reaction unit 9 starts reaction heating test-strips or tester 5, nucleic acid is made to carry out isothermal duplication within the extremely short time, and discharge fluorescence, proving installation 8 detects fluorescence and is passed through by light signal and is converted into digital signal, be presented on screen 22, also can be simultaneously direct human eye in some cases by the change of the outward appearance in transparent amplifier 23 observation test bar or tester 5 or color, the observation of the data shown by screen 22 or transparent amplifier 23, because strong and weak the having that it's too late how much proportional content is with nucleic acid to be detected in sample of signal.Thus judge the presence or absence (positive or negative) of cause of disease to be checked in institute's test sample product and quantize size.Therefore, can carry out whether ill and ill degree judges, namely complete the diagnosis of disease.Certainly, can extract USB flash disk after using, after power-off, all devices and system are all in off-position.Like this, reaction unit 9 expands for accelerating to increase, then proving installation 8 transmits for detection, inverted signal data, and control chip 6 controls the operation of each parts for entirety, test-strips or tester 5 detect the connection of box 4 and control chip 6 for reacting break-make simultaneously with biological sample to be detected, and USB interface 3 is for power supply input power supply.Sample extraction can be made so simple more fast, expense is cheaper, shorten amplification process subsequent step, greatly shorten the time of reading result, diagnose as early as possible and whether suffer from disease and ill degree, benefiting masses, being designed with different test-strips or tester 5 for selecting for different diseases or different testing goals, detecting USB flash disk can prolonged and repeatedly use.Reusability is high, good reliability, accuracy of judgement.That structure is simple, that upstream sample is extracted is more quick relative to the advantage of prior art, simply, expense relative moderate, amplification process correlation step after simultaneously shortening, and then shorten the time of reading result, save cost, judge fast.The nucleic acid extraction suit that extracting Biosample needs comprises the rubber tip dropper of built-in nucleic acid filtering membrane and the sample accommodation bottle of nucleic acid extracting reagent is housed, and uses this suit can detect the biological detection sample of needs.Detection USB flash disk for medical diagnosis on disease of the present invention, detects nucleic acid (DNA, RNA), gene sequencing, protein for (but being not limited to) in-vitro diagnosis and scientific research, sugar and other molecule; Test-strips or tester (prod) 5 are for (but being not limited to) lateral flow immunoassay (such as conceived test etc.), enzyme linked immunological test (ELISA) (such as HIV, HBV etc.), lateral flow tester (prod) (such as blood sugar test) etc.; More specifically, when alleged test-strips or tester (prod) 5 are taken up for the bed of the diseases such as bacterium, disease of viral infection, hereditary disease, diagnosis detects (Point-Of-Care Testing, POCT); Further, alleged test-strips or tester 5 (prod) can be used for veterinary science, agricultural, food industry, biological anti-probably and the field such as environmental protection.Wherein, detect box 4 and can have traditional microplate reader (enzyme-linked immunosorbent assay instrument) function concurrently, realize the POCT of the enzyme linked immunosorbent detection (ELISA in a USB Flash Drive) in USB flash disk.In addition, screen 22 can be LCDs also can be touch-screen.USB flash disk shell body comprises the outer upper cover 1 of USB flash disk and the outer lower cover 2 of USB flash disk, and the outer upper cover 1 of USB flash disk and the outer lower cover 2 of USB flash disk of fastening form cavity, detect box 4 etc. for holding,
A kind of detection USB flash disk for medical diagnosis on disease of the present invention, please refer to Fig. 1 to Fig. 8, the basis of previously described technical scheme can be specifically: described test-strips or tester 5 are the elongate in shape be made up of conductive material that described test-strips or tester 5 side to opposite side are disposed with discarded object uptake zone 10, test section 11, reaction zone 12 and sample extraction district 13.The reaction zone 12 of test-strips or tester 5 is for amplified reaction under the effect of reaction unit 9, sample area is for accepting the biological sample to be detected after process and extracting utility, and 11, test section is extracted for proving installation 8 information that detects and is converted into digital signal and stores, show and judge.10, discarded object uptake zone be for absorption reaction after discarded object.Such advantage to split in order, ensures the accuracy detecting data.Preferred technical scheme is described test-strips or is provided with filtrating area 14 between tester 5 test section 11 and reaction zone 12, between reaction zone 12 and described sample extraction district 13 further.The advantage arranging filtrating area 14 at this two place adsorption treatment can fall mishmash or nonspecific products further, improves Sensitivity and Specificity.Can also be that rear, described sample extraction district 13 is provided with staff by holding place 15.This is the preferred setting of outside plug type test-strips or tester 5, the test-strips of outside plug type or tester 5 detect in box 4 because must insert from outside, therefore arrange staff the hand-held test-strips of handled easily personnel or tester 5 to insert and detect in box 4 by holding place 15, but can not contact with sample extraction district 13, and pollute biological specimen, the further accuracy improving detection, ensures the correctness of diagnosis.Can also be that described USB flash disk shell body top is provided with recessed adding mouth 16, described detection box 4 top is provided with sample extraction system 17, and described adding mouth 16 and sample extraction system 17 position are all corresponding with the position, sample extraction district 13 of described test-strips or tester 5.Like this, when built-in testing bar or tester 5 need to use, then directly drip biological sample from adding mouth 16, if outside plug type test-strips or tester 5, then after inserting test-strips or tester 5, also can drip biological sample from adding mouth 16.Sample extraction system 17 is then for extracting suitable sample.Further preferred technical scheme be described sample extraction system 17 comprise from top to bottom set gradually sample preparation upper strata 18, sample preparation lower floor 19, nucleic acid absorption layer 20 and discarded object adsorbed layer 21, described sample preparation upper strata 18 is corresponding with described adding mouth 16 position.The advantage of such sample extraction system 17 both to have utilized the on-line system 17 of integration to extract sample, also in conjunction with other method, can extract more unmanageable sample, be directly added to the sample application zone of outside plug type test-strips or tester 5.
in addition,the sample preparation upper strata 18 that sample extraction system 17 comprises, sample preparation lower floor 19, nucleic acid absorption layer 20 and discarded object adsorbed layer 21, can as a whole piece, after the process of a sample has detected, taken out this integral blocks and abandoned.When to process detect another sample be time, put into a new sample extraction system 17.The sample preparation upper strata 18 that sample extraction system 17 comprises, sample preparation lower floor 19, nucleic acid absorption layer 20 and discarded object adsorbed layer 21, and test-strips or tester 5 are single use, advantage is the cross pollution avoided like this in sample extraction process.Detection USB flash disk for medical diagnosis on disease of the present invention can be prolonged and repeated for various test-strips or tester 5.In addition detection box 4 freely can be extracted out in USB flash disk shell body, after being convenient to do certain cleaning if desired, then put back to.
A kind of detection USB flash disk for medical diagnosis on disease of the present invention, please refer to Fig. 1 to Fig. 8, the basis of previously described technical scheme can also be: the both positive and negative polarity of described USB interface 3 is connected with the both positive and negative polarity of control chip 6 respectively, the both positive and negative polarity of described control chip 6 is connected with described detection box 4 both positive and negative polarity respectively with by test-strips or tester 5, the both positive and negative polarity of described control chip 6 is connected respectively with the both positive and negative polarity of the both positive and negative polarity of proving installation 8 and reaction unit 9, and the both positive and negative polarity of described control chip 6 is connected with the both positive and negative polarity of screen 22 respectively.Like this, can control at control chip 6 indices detecting box 4, control startup or the operation of reaction unit 9 and proving installation 8, make testing process short as far as possible, testing result is accurate as far as possible simultaneously.USB interface 3 can be powered to control chip 6, and control chip 6 also controls the display of screen 22 in addition.
A kind of detection USB flash disk for medical diagnosis on disease of invention, please refer to Fig. 1 to Fig. 8, the basis of previously described technical scheme can also be: above described circuit board 7, be also provided with flash chip 24, described flash chip 24 is connected with control chip 6, and described flash chip 24 is electrically connected with screen 22 and/or data communication is connected.The advantage arranging flash chip 24 testing result to be converted into autostore after data, also directly testing result data directly can be transferred to when USB interface 3 is connected to computer or smart mobile phone time in computer or smart mobile phone and preserve backup, and compare with result before, check state of an illness recovery situation etc.Flash chip 24 is connected with screen 22, directly can be presented on screen 22 by the digital signal after conversion, convenient in very first time display testing result, also facilitates the work such as follow-up printing.Can also be that described proving installation 8 comprises the photosensor 25, photoelectric sensor 26 and the analog to digital converter 27 that connect successively, described analog to digital converter 27 is connected with a flash chip 24, and described photosensor 25, photoelectric sensor 26 and analog to digital converter 27 are all connected with described control chip 6.Photosensor 25 is positioned at above the test section 11 of test-strips or tester 5, and photosensor 25 detects fluorescent value in test section 11, and by photoelectric sensor 26, light signal is converted into electric signal, electric signal is converted to digital signal.Strong and weak the having that it's too late how much proportional content is with nucleic acid to be detected in sample of its signal.Thus judge the presence or absence (positive or negative) of cause of disease to be checked in institute's test sample product and quantize size.Certainly other proving installation 8 is also fine, as long as the testing result on the test section 11 in test-strips or tester 5 can be converted into the data that can show and can read.Can also be that described reaction unit 9 comprises well heater 30, temperature sensor 29 and temperature controller 28, described well heater 30, temperature sensor 29 be all connected with control chip 6 with temperature controller 28.Well heater 30 is for the reaction zone 12 of heating test-strips or tester 5 when reacting, accelerate nucleic acid amplification, improve detection efficiency, temperature sensor 29 is all connected with control chip 6 with temperature controller 28, the temperature value sensed is passed to control chip 6, and control chip 6 control temperature controller 28 control heater 30 normally works, and heats rapidly or does not work, and then control the nucleic acid amplification speed of reaction zone 12, and then control the time of diagnosis and detection.Preferred technical scheme for be provided with collet 31 bottom well heater 30 further, well heater 30 sidepiece can arrange collet 31, but the part in well heater 30 orientating reaction district 12 can not arrange collet 31, the effect of collet 31 is isolated heats, and avoiding affects temperature sensor 29 and temperature controller 28.
A kind of detection USB flash disk for medical diagnosis on disease of invention, please refer to Fig. 1 to Fig. 8, the basis of previously described technical scheme can also be: described circuit board 7 four jiaos of places are provided with spike, described detection box 4 tetrapod is erected on described spike, described control chip 6 is arranged between described circuit board 7 and described detection box 4, arranges flash chip 24 between described circuit board 7 and described detection box 4.The advantage that such flash chip 24 set-up mode brings makes the result of USB flash disk compact as far as possible, and the smaller volume of USB flash disk, space availability ratio is higher, reduces costs.And erection the more convenient test-strips of detection box 4 or tester 5 insert.Preferred technical scheme is that USB flash disk shell body side is provided with and resupinately can renovates 32 further, when needs insert test-strips or tester 5, and upwards flip 32, USB flash disk shell body one side opening, insert test-strips or tester 5, then put down and renovate 32, start to detect.Can also be that described detection box 4 comprises top lid and bottom box, described proving installation 8 is positioned at described top cover lower surface place, described reaction unit 9 is positioned at box upper surface place, the described end, described proving installation 8 and described reaction unit 9 are arranged at head and the afterbody of described detection box 4 respectively, stagger setting in both positions.Like this, the reaction zone 12 of reaction unit 9 and the proving installation 8 corresponding test-strips of difference or tester 5 and test section 11, reaction efficiency is higher, and reaction is more abundant, and test is more accurate, and accurate rate is higher.And the space availability ratio that arranges rear detection box 4 of staggering is higher, detecting box 4 can be flat as much as possible, and volume is little as far as possible.Reduce costs and expand the scope of application.In addition, bottom detection box 4, respectively there is a groove at two ends, as the discarded object absorption cell 33 for receiving issuable waste gas, waste liquid the like waste.
Above-mentionedly only several specific embodiments in the present invention to be illustrated; but can not as protection scope of the present invention; every according to the change of the equivalence done by design spirit in the present invention or to modify or equal proportion zooms in or out, all should think and fall into protection scope of the present invention.
Claims (10)
1. the detection USB flash disk for medical diagnosis on disease, it is characterized in that: comprise USB flash disk shell body, USB interface, detect box, test-strips or tester, control chip, circuit board, proving installation and reaction unit, described USB interface is located at described USB flash disk shell body one end and is stretched out described USB flash disk shell body, described circuit board is positioned at the described USB flash disk shell body bottom, described control chip is arranged at described circuit board, described detection carriage is located at above described control chip, described proving installation and described reaction unit are all arranged in described detection box, described test-strips or tester can insert in described detection box from outside to inside or be built in described detection box, described proving installation and described reaction unit lay respectively at described test-strips or the upper and lower both sides of tester, described detection box, reaction unit and described proving installation are electrically connected with control chip respectively, described test-strips or tester can remove being electrically connected with described detection box of formula, USB interface is electrically connected with described control chip, described USB flash disk shell body top surface is provided with screen and/or transparent amplifier, described screen is electrically connected with described control chip and/or data communication is connected.
2. a kind of detection USB flash disk for medical diagnosis on disease according to claim 1, it is characterized in that: described test-strips or tester are the elongate in shape be made up of conductive material, described test-strips or tester side to opposite side are disposed with discarded object uptake zone, test section, reaction zone and sample extraction district.
3. a kind of detection USB flash disk for medical diagnosis on disease according to claim 2, it is characterized in that: described USB flash disk shell body top is provided with recessed adding mouth, described detection box top is provided with sample extraction system, and described adding mouth and sample extraction system position are all corresponding with the sample extraction zone position of described test-strips or tester.
4. a kind of detection USB flash disk for medical diagnosis on disease according to claim 3, it is characterized in that: described sample extraction system comprise from top to bottom set gradually sample preparation upper strata, sample preparation lower floor, nucleic acid absorption layer and discarded object adsorbed layer, described sample preparation upper strata is corresponding with described adding mouth position.
5. a kind of detection USB flash disk for medical diagnosis on disease according to any one claim of Claims 1-4, it is characterized in that: the both positive and negative polarity of described USB interface is connected with the both positive and negative polarity of control chip respectively, the both positive and negative polarity of described control chip is connected with described detection box both positive and negative polarity respectively with by test-strips or tester, the both positive and negative polarity of described control chip is connected respectively with the both positive and negative polarity of the both positive and negative polarity of proving installation and reaction unit, and the both positive and negative polarity of described control chip is connected with the both positive and negative polarity of screen respectively.
6. a kind of detection USB flash disk for medical diagnosis on disease according to any one claim of Claims 1-4, it is characterized in that: described circuit board is also provided with flash chip, described flash chip is connected with control chip, and described flash chip is electrically connected with screen and/or data communication is connected.
7. a kind of detection USB flash disk for medical diagnosis on disease according to any one claim of Claims 1-4, it is characterized in that: described proving installation comprises the photosensor, photoelectric sensor and the analog to digital converter that connect successively, described analog to digital converter is connected with a flash chip, and described photosensor, photoelectric sensor and analog to digital converter are all connected with described control chip.
8. a kind of detection USB flash disk for medical diagnosis on disease according to any one claim of Claims 1-4, it is characterized in that: described reaction unit comprises well heater, temperature sensor and temperature controller, described well heater, temperature sensor are all connected with control chip with temperature controller.
9. a kind of detection USB flash disk for medical diagnosis on disease according to any one claim of Claims 1-4, it is characterized in that: described circuit board corner place is provided with spike, described detection box tetrapod is erected on described spike, described control chip is arranged between described circuit board and described detection box, arranges flash chip between described circuit board and described detection box.
10. a kind of detection USB flash disk for medical diagnosis on disease according to any one claim of Claims 1-4, it is characterized in that: described detection box comprises top lid and bottom box, described proving installation is positioned at described top cover lower surface place, described reaction unit is positioned at box upper surface place, the described end, described proving installation and described reaction unit are arranged at head and the afterbody of described detection box respectively, stagger setting in both positions.
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| CN108883417A (en) * | 2016-01-20 | 2018-11-23 | 特里夫科技公司 | Instant nucleic acid amplification and detection |
| CN110300893A (en) * | 2017-02-21 | 2019-10-01 | 硕腾服务有限责任公司 | Diagnostic test reader system |
| CN112538423A (en) * | 2020-12-23 | 2021-03-23 | 广州和实生物技术有限公司 | Integral nucleic acid extraction and detection device and use method thereof |
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