CN104770361A - Supplied-liver quickly-fixed perfusion device for liver transplant - Google Patents
Supplied-liver quickly-fixed perfusion device for liver transplant Download PDFInfo
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- CN104770361A CN104770361A CN201510107314.6A CN201510107314A CN104770361A CN 104770361 A CN104770361 A CN 104770361A CN 201510107314 A CN201510107314 A CN 201510107314A CN 104770361 A CN104770361 A CN 104770361A
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Abstract
The invention relates to the medicine field, especially relates to a perfusion device, which can rapidly carry out connection and perfusion when obtaining a supplied liver in an organism (liver) transplant operation, and specifically relates to a supplied-liver quickly-fixed perfusion device for liver transplant. The perfusion device comprises a puncture guiding device and a connecting ring for connecting a perfusion pipe. The puncture guiding device is a puncture steel wire, a contractible and magnetic ring is arranged on the top end of the steel wire, the top end of the connecting ring is in a conical shape, the bottom of the connecting ring is connected to a perfusion pipe, a unidirectional valve is arranged in the bottom of the connecting ring, the top of the connecting ring is made of an iron-containing material, the top of the connecting ring is matched with the contractible ring, and the top of the connecting ring and the contractible ring absorb on each other through magnetic force. The operation of the device is simple, practicable, and pertinent. The device is mainly used to carry out rapid perfusion when obtaining a supplied liver in a liver transplant operation, and is capable of rapidly and effectively performing liver perfusion so as to obtain a high quality liver.
Description
Technical field
The present invention relates to a kind of field of medicaments, particularly relate to connection and the perfusion of accurately carrying out device for casting when obtaining for liver in organ transplant (liver) art fast, specifically fix device for casting fast for liver in a kind of transplantation of liver.
Background technology
Current transplantation of liver has become the conventional therapy means for the treatment of End-stage liver disease, and this year, after liver transplantation survival rate improved constantly along with the continuous popularization of China's Technology of Liver Transplantation in China and improvement.Incidence of complications is also declining year by year.In transplantation of liver, be hepatocyte in situ perfusion for one of key technology in the acquisition of liver.How accurately fixing the and perfusion of pipe is put in location carrying out fast is that the technical difficult problem obtaining high-quality liver source exists.
When tradition obtains for liver, detect liver rapidly after opening abdomen, understand with or without cirrhosis, Liver masses and Severe fatty liver, patient mentions small intestine, by assistant's ligation mesostenium, cut off posterior peritoneum above pelvis population, appear abdominal aorta, cut off antetheca above its bifurcated, proximally insert the Foley catheter of band 2 ~ 3 side openings after repacking, insertion depth is above air bag to abdominal aorta plane of the opening, injects 25ml physiological saline, pour into 0 ~ 4 DEG C of irrigating solution in air bag.After completing abdominal aortic cannulation, begin column portal vein pours into.Assistant is tractive duodenum downwards, and operator rives pancreatic head, can find the root of superior mesenteric vein at pancreas rear, cut off its antetheca, insert self-control portal catheterization, degree of depth 2-3cm, to prevent from inserting deeply to branch of portal vein, and ligation splenic vein.Add prick fixing after, start perfusion.This operation, needs operator to want skillfully accurately locate catheter depth, and under assistant, carries out rapidly intubate fix.But in this process, easily occur the situation that intubate is excessively dark, at this moment perfusate flows to right half liver top, easily causes left and right liver perfusion insufficient; Simultaneously because left lateral lobe of liver is close to heart, generally lower the temperature in filling process comparatively slow, cause the left and right hepatic ischemia time variant.In this external intubate fixation procedure, tradition toe-in is pricked, and the difference according to patient's skilled operation degree also has impact to the overall perfusion device set-up time.Meanwhile, lack the device preventing liquid reflux in tradition perfusion pipeline, pouring liquid relies on gravity factor to enter for liver completely, can cause the reflux of perfusion liquid at any time, cause rate of flooding to slow down in whole filling process because of various factors.Therefore, find accessory in and be used for quick position installation device for casting, patient can be facilitated to operate, the basis of time greatly reducing infusion cannula ensures Donor liver quality, also have comparatively huge meaning to the raising of the prognosis quality of life of liver-transplantation patients.
Summary of the invention
The invention proposes a kind of accessory fixed fast, pour in transplantation of liver obtains for liver, and this device is easy and simple to handle feasible, with strong points, can shorten the device for casting set-up time and complete liver perfusion fast, preventing perfusion liquid reflux.
Fix device for casting fast for liver in transplantation of liver, comprise guiding puncture device and the connecting ring being connected intrusion pipe, described guiding puncture device is the puncture steel wire of top with collapsible ring, and described collapsible endless belt is magnetic; Described connecting ring top is taper, is connected bottom described connecting ring with intrusion pipe, and connecting ring bottom internal is provided with the flap valve of one-way flow, and connecting ring top is iron-bearing materials preparation, connecting ring top and collapsible ring mutually adaptive, and mutually to be adsorbed by magnetic.
Preferably, the conical surface on described connecting ring top is provided with cribriporal.
Preferably, described puncture steel wire is also provided with conduit outward.
Preferably, the collapsible ring on described guiding puncture device top controls to make it open by puncture steel wire.
Preferably, described puncture steel wire length is 30 centimetres.
Preferably, described connecting ring internal diameter is 0.8 centimetre, is highly 2 centimetres.
Preferably, the composite biological material that is made up of stainless steel, nickel/platinum, polyurethane, polytetrafluoroethylene (PTFE) etc. of described puncture steel wire; The composite biological material that the biological character that described connecting ring top conical section is made up of iron compound is stable, can link with the collapsible ring magnetic in puncture needle top; Remaining structure is ABS plastic.
Below the present invention is set forth further:
Fix device for casting be fast made up of two parts for liver in transplantation of liver, comprise the liver puncture guiding device that head end hides the collapsible tensioner ring of magnetic and the circular connecting ring that the head end matched with it is designed for flapper-type.
1) head end hides the liver puncture guiding device of the collapsible tensioner ring of magnetic: its shape is totally the slightly soft liver puncture steel wire of an elongated quality, length is 30 centimetres, the composite biological material that its material is made up of stainless steel, nickel/platinum, polyurethane, polytetrafluoroethylene (PTFE) etc., mainly playing guiding puncture enters portal vein; Its head end is with a contractile endless means, and its material is that combination property is good, the ferrite magnetic material of stable chemical performance, stretches (internal diameter is 0.8 centimetre), plays the effect of hemangiectasis by tail end after can being operated.
2) connecting ring: it matches with liver puncture guiding device.Connecting ring head end is tapered, material is iron compound, match with liver puncture tensioner ring, both form magnetic absorption quick anastomosis device, and play the effect of fixing tensioner ring, its tapering point is sharp-pointed, vascular wall can be punctured fast, play and get through blood vessel function, its surface is designed for cribriporal, facilitates perfusion liquid to flow rapidly into liver; Connecting ring inside is designed for unidirectional valve, makes perfusion can only by via can not adverse current in external world's inflow liver; The intrusion pipe connector that tail end is, for connecting perfusion pipeline.The composite biological material that the biological character that described connecting ring top conical section is made up of iron compound is stable, can link with the collapsible ring magnetic in puncture needle top; Remaining structure is the ABS plastic (acrylonitrile-butadiene-styrene (ABS)) of good combination property, stable chemical performance, and internal diameter is 0.8 centimetre, is highly 2 centimetres.
The present invention and tradition obtain compared with the method for pouring into for liver has obvious beneficial effect:
(1) quick position hemangiectasis, open abdomen visit and liver after by liver puncture guiding device arrive rapidly portal vein lower end go forward side by side line pipe road connect.
(2) feature making full use of magnetic material carries out the connection of connecting ring and guiding device, punctures blood vessel fast and carries out hemoperfusion, avoids the artificial difference of the operating personnel pricked with line cover traditionally.
(3) adopt the design of flap valve perfusion model, perfusion liquid can only be flowed by a direction, ensure that the one-way in filling process, improves charging efficiency.
The present invention adopts puncture steel wire, especially the length of 30 centimetres, can avoid the situation occurring that intubate causes left and right liver perfusion insufficient excessively deeply; Connecting ring head end is tapered, material is iron compound, match with liver puncture tensioner ring, both form magnetic absorption quick anastomosis device, and play the effect of fixing tensioner ring, its tapering point is sharp-pointed, vascular wall can be punctured fast, play and get through blood vessel function, its surface is designed for cribriporal, facilitates perfusion liquid to flow rapidly into liver; Connecting ring inside is designed for unidirectional valve, makes perfusion can only by via can not adverse current in external world's inflow liver; The intrusion pipe connector that tail end is, for connecting perfusion pipeline.Operation is simple and feasible in the present invention, with strong points, is mainly used in completing quick filling when obtaining for liver in transplantation of liver.The present invention obviously shortens the set-up time of device for casting, for carrying out liver perfusion fast and efficiently, obtains and high-qualityly provides effective technical guarantee for liver.
Accompanying drawing explanation
Fig. 1 is the structural representation of embodiment 1 guiding puncture device.
Fig. 2 is the change procedure schematic diagram of the collapsible ring on embodiment 1 guiding puncture device top.
Fig. 3 is the structural representation of embodiment 1 connecting ring.
Fig. 4 is the inner unidirectional valve structural representation of connecting ring.
Fig. 5 is embodiment 1 guiding puncture device is combined for transplantation of liver schematic diagram with connecting ring.
Embodiment
Set forth the present invention further below in conjunction with specific embodiment, should be understood that following examples are only not used in for illustration of the present invention and limit the scope of the invention.
In the following example, method therefor if no special instructions, is conventional method.Material required in following examples or reagent, be market if no special instructions and buy.
Embodiment 1
Fig. 1-2 and Fig. 3-4 is respectively the liver puncture guiding device that head end hides the collapsible tensioner ring of magnetic and the circular connecting ring matched with it.As shown in Figure 1-2, liver puncture guiding device is made up of guide wire 2 and conduit 1, and its material is the composite biological material that material is made up of stainless steel, nickel/platinum, polyurethane, polytetrafluoroethylene (PTFE) etc., and matter is soft, plastic, and mainly playing guiding puncture enters portal vein.Its guide wire 2 head end is with a collapsible ring 2-1, collapsible ring 2-1 is connected through special process by discontinuous fragment, conveniently contraction and diastole, its material is that combination property is good, the ferrite magnetic material of stable chemical performance, stretches (stretch rear be the annulus of 0.8 centimetre for internal diameter), plays the effect of hemangiectasis by guide wire 2 tail end after can operate.
As shown in Figure 3-4, for head end is taper, the inner circular connecting ring 3 designed for flapper-type, the material of whole connecting ring 3 is the ABS plastic (acrylonitrile-butadiene-styrene (ABS)) of good combination property, stable chemical performance, and internal diameter is 0.8 centimetre, is highly 2 centimetres.Its head end is pyramidal structure, and conical surface designs for sieve-like, and material is for being by iron compound, and the collapsible ring 2-1 after can expanding with liver puncture guiding device top after penetrating blood vessel relies on magnetic to connect, fixing collapsible ring 2-1.Sharp taper header terminal design energy quick penetration blood vessel, forms perfusion channel.Tail end is intrusion pipe connector, for linking perfusion pipe; Connecting ring 3 inside is provided with unidirectional valve (Fig. 4), makes perfusion fluid can only can not adverse current by flow into via the external world in liver, thus reaches the effect of quick filling.
Fig. 5 is the operating process of whole device, supplying in liver acquisition process, open abdomen to visit rapidly and after liver situation, arrival portal vein lower end is penetrated via liver surface with liver puncture guiding device, control the collapsible ring 2-1 of top magnetic by the handle of guide wire 2 expand and prop up portal vein, now utilize magnetic attracting make rapidly magnetic collapsible ring 2-1 be connected annulus mutually 3 connect fixing, and be rotationally connected ring 3 a little can the collapsible ring 2-1 of magnetic of firmly fastening internal blood vessel, such connection completes.After this insert the tail end connecting connecting ring 3 with intrusion pipe, start perfusion.
Be not difficult to find from foregoing description, the present invention and tradition obtain compared with the method for pour into for liver has obvious intrinsic advantage: (1) quick position hemangiectasis, visits and guides arrival portal vein lower end rapidly to go forward side by side the connection of line pipe road by liver puncture after liver opening abdomen.(2) feature making full use of magnetic material is carried out connection and is put pipe, and taper head end punctures blood vessel fast and carries out hemoperfusion, avoids the artificial difference of the operating personnel pricked with line cover traditionally.(3) adopt the design of flap valve perfusion model, perfusion liquid can only be flowed by a direction, ensure that the liquid flow one-way in filling process, improves charging efficiency.The present invention obviously shortens the set-up time of device for casting, for carrying out liver perfusion fast and efficiently, obtains and high-qualityly provides effective technical guarantee for liver.
Finally, it is also to be noted that enumerate above be only specific embodiments of the invention son.Obviously, the invention is not restricted to above examples of implementation, many distortion can also be had.All distortion that those of ordinary skill in the art can directly derive from content disclosed by the invention or associate, all should think protection scope of the present invention.
Claims (7)
1. fix device for casting fast for liver in transplantation of liver, it is characterized in that: comprise guiding puncture device and the connecting ring being connected intrusion pipe, described guiding puncture device is the puncture steel wire of top with collapsible ring, and described collapsible endless belt is magnetic; Described connecting ring top is taper, is connected bottom described connecting ring with intrusion pipe, and connecting ring bottom internal is provided with the flap valve of one-way flow, and connecting ring top is iron-bearing materials preparation, connecting ring top and collapsible ring mutually adaptive, and mutually to be adsorbed by magnetic.
2. fix device for casting fast for liver in transplantation of liver according to claim 1, it is characterized in that: the conical surface on described connecting ring top is provided with cribriporal.
3. fix device for casting fast for liver in transplantation of liver according to claim 1, it is characterized in that: described puncture steel wire is also provided with conduit outward.
4. fix device for casting fast for liver in transplantation of liver according to claim 1, it is characterized in that: the collapsible ring on described guiding puncture device top controls to make it open by puncture steel wire.
5. fix device for casting fast for liver in transplantation of liver according to claim 1, it is characterized in that: described puncture steel wire length is 30 centimetres.
6. fix device for casting fast for liver in transplantation of liver according to claim 1, it is characterized in that: described connecting ring internal diameter is 0.8 centimetre, is highly 2 centimetres.
7. fix device for casting fast for liver in transplantation of liver according to claim 1, it is characterized in that: the composite biological material that described puncture steel wire is made up of stainless steel, nickel/platinum, polyurethane, polytetrafluoroethylene (PTFE) etc.; The composite biological material that the biological character that described connecting ring top conical section is made up of iron compound is stable, can link with the collapsible ring magnetic in puncture needle top; Remaining structure is ABS plastic.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510107314.6A CN104770361B (en) | 2015-03-11 | 2015-03-11 | Supplied-liver quickly-fixed perfusion device for liver transplant |
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| CN201510107314.6A CN104770361B (en) | 2015-03-11 | 2015-03-11 | Supplied-liver quickly-fixed perfusion device for liver transplant |
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| CN104770361B CN104770361B (en) | 2017-05-17 |
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Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111356364A (en) * | 2017-11-20 | 2020-06-30 | 体沃索股份有限公司 | Apparatus for perfusing an isolated organ |
| CN112790188A (en) * | 2019-10-28 | 2021-05-14 | 西安交通大学医学院第一附属医院 | Rapid perfusion device for liver supply in liver transplantation |
| CN112998822A (en) * | 2021-03-18 | 2021-06-22 | 中南大学湘雅医院 | Puncture cannula and perfusion catheter for perfusion of abdominal organ transplantation donor |
| CN115252072A (en) * | 2022-06-15 | 2022-11-01 | 中国人民解放军总医院第七医学中心 | Liver supplying quick fixation perfusion device in liver transplantation |
| US11844345B2 (en) | 2005-06-28 | 2023-12-19 | Transmedics, Inc. | Systems, methods, compositions and solutions for perfusing an organ |
| US11856944B2 (en) | 2011-04-14 | 2024-01-02 | Transmedics, Inc. | Organ care solution for ex-vivo machine perfusion of donor lungs |
| US11903381B2 (en) | 2014-06-02 | 2024-02-20 | Transmedics, Inc. | Ex vivo organ care system |
| US11917991B2 (en) | 2007-03-20 | 2024-03-05 | Transmedics, Inc. | Systems for monitoring and applying electrical currents in an organ perfusion system |
| US11963526B2 (en) | 2014-12-12 | 2024-04-23 | Transmedics, Inc. | Apparatus and method for organ perfusion |
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Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US11844345B2 (en) | 2005-06-28 | 2023-12-19 | Transmedics, Inc. | Systems, methods, compositions and solutions for perfusing an organ |
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| US11903381B2 (en) | 2014-06-02 | 2024-02-20 | Transmedics, Inc. | Ex vivo organ care system |
| US11944088B2 (en) | 2014-06-02 | 2024-04-02 | Transmedics, Inc. | Ex vivo organ care system |
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| CN112790188A (en) * | 2019-10-28 | 2021-05-14 | 西安交通大学医学院第一附属医院 | Rapid perfusion device for liver supply in liver transplantation |
| CN112998822A (en) * | 2021-03-18 | 2021-06-22 | 中南大学湘雅医院 | Puncture cannula and perfusion catheter for perfusion of abdominal organ transplantation donor |
| CN115252072A (en) * | 2022-06-15 | 2022-11-01 | 中国人民解放军总医院第七医学中心 | Liver supplying quick fixation perfusion device in liver transplantation |
| CN115252072B (en) * | 2022-06-15 | 2024-04-19 | 中国人民解放军总医院第七医学中心 | Quick fixing and pouring device for liver in liver transplantation |
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