CN104740216A - Traditional Chinese medicine for treating coronary heart disease and stenocardia - Google Patents
Traditional Chinese medicine for treating coronary heart disease and stenocardia Download PDFInfo
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- CN104740216A CN104740216A CN201510175232.5A CN201510175232A CN104740216A CN 104740216 A CN104740216 A CN 104740216A CN 201510175232 A CN201510175232 A CN 201510175232A CN 104740216 A CN104740216 A CN 104740216A
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Abstract
The invention discloses a traditional Chinese medicine for treating coronary heart disease and stenocardia. The traditional Chinese medicine is prepared from the following raw herbal materials in parts by weight: 15 parts of snakegourd fruits, 10 parts of allium macrostemon, 10 parts of salviae miltiorrhizae, 5 parts of ligusticum wallichii, 15 parts of white atractylodes rhizome, 12 parts of pseudo-ginseng, 12 parts of pinellia ternate, 15 parts of schisandra chinensis and 10 parts of red flowers. According to the clinical experiments, the traditional Chinese medicine can be used for safely and effectively for treating coronary heart disease and stenocardia.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine being used for the treatment of angina pectoris.
Background technology
Angina pectoris is the commonly encountered diseases of cardiovascular system, due to cardiac muscle sharply, the ictal chest pain that causes of temporary transient ischemia and anoxia or chest uncomfortable, cause blood supply insufficiency primarily of coronary atherosclerosis and spasm and cause, belong to the traditional Chinese medical science " obstruction of qi in the chest and cardialgia " category.Primary disease is mainly in middle-aged and elderly people, and male is more than women, common with brain worker, and the serious harm mankind's is healthy, is one of principal disease of middle-aged and elderly people.Angina pectoris belongs to the category such as Chinese medicine " thoracic obstruction ", " angina pectoris ", " precordial pain with cold limbs ".Modern medicine thinks that its pathogeny is due to abnormalities of sugar/lipid metabolism, and blood viscosity increases and causes that coronary arterial wall damages, lipid is calm, atherosclerotic plaque is formed, thus makes coronary artery luminal stenosis, deficiency myocardial blood supply and causing.Chinese medicine is thought, the basic pathogenesis of the thoracic obstruction is hypofunction of YANG QI in chest, blood stasis due to qi deficiency, and channels numbness hinders, stagnation of Qi and phelgm, and wherein common with the card of blood stasis due to qi deficiency, the resistance of channels numbness.Qi being the governor of blood, blood being the material foundation of QI, the capable then blood of gas, the stagnation of QI deficiency of vital energy then blood stasis.Treatment is when consolidating as rich with QI invigorating. and be auxiliary with blood circulation promoting and blood stasis dispelling, removing obstruction in the collateral to relieve pain.
Medical material present Research involved in the present invention is as follows:
Fructus Trichosanthis [source] this product is the dry mature seed of cucurbitaceous plant Fructus Trichosanthis or trichosanthes rosthornii Harms.Autumn, harvesting ripe fruit, cut open, took out seed, cleaned, dried.[nature and flavor] are sweet, cold.[return through] returns lung, stomach, large intestine channel.[function cures mainly] moistening the lung and resolving phlegm, laxation relieving constipation.Stick for cough caused by dryness expectorant, dryness of the intestine constipation.[usage and dosage] takes orally: decoct soup, 9 ~ 15g.[attention] should not with Aconitum medical material with using.[extracts] " China's book on Chinese herbal medicine ".
Bulbus Allii Macrostemonis [another name] Chinese onion root (" Handbook of Prescriptions for Emergencies "), Allium chinense (" Luchuan book on Chinese herbal medicine "), major part colza (" Xinjiang medical material "), wild Bulbus Allii, little DUSUAN (" Chinese medicine shape sex experience differential method "), Bulbus Allii schoenoprasi, residence Bulbus Allii (" Hebei medical material "), Bulbus Allii Macrostemonis head.The bulb that [source] is liliaceous plant Allium macrostemon or Chinese onion.The north is many in spring, and south is many gathers between the autumn in summer.Grub out, removing stem and leaf and fibrous root, cleaned, well-done with boiling water, dry or dry.This product must put dry place, damp-proof and moth-proof.[nature and flavor] are pungent, bitter, temperature.[return through] enters liver, lung, heart channel.[function cures mainly] regulates the flow of vital energy, and the chest stuffiness relieving activates yang, eliminating stagnation.Control the thorough back of the body of obstruction of qi in the chest and cardialgia, gastral cavity painful abdominal mass is not relaxed, and retches, heavy after dysentery, furuncle.[usage and dosage] takes orally: decoct soup, 6 ~ 15g.The careful clothes of [attention] deficiency of vital energy person.[extracts] " China's book on Chinese herbal medicine ".
Radix Salviae Miltiorrhizae [another name] Arisaema balansae Engl., Radix Campylotropis Hirtella (Herba Myrsines Africanae), Herba Wedeliae Wallichii root, blood mountain root, RADIX SALVIAE MILTIORRHIZAE, Radix Salviae Miltiorrhizae.[source] this product is the dry root and rhizome of labiate Radix Salviae Miltiorrhizae.Spring, Qiu Erji excavate, removing silt, dry.[nature and flavor] are bitter, are slightly cold.[return through] GUIXIN, Liver Channel.[function cures mainly] stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, clear away heart-fire relieving restlessness.For menoxenia, amenorrhea dysmenorrhea, lump in the abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia; Hepatosplenomegaly, angina pectoris.[usage and dosage] takes orally: decoct soup, 9 ~ 15g.[attention] should not with Rhizoma et radix veratri (Radix Rhizoma Veratri) with using.[extracts] " China's book on Chinese herbal medicine ".
Rhizoma Chuanxiong [another name] rhizome of chuanxiong Qiong, Rhizoma Chuanxiong.[source] this product is the dry rhizome of samphire Rhizoma Chuanxiong.Summer shows outstanding when joint dish on stem, and excavates during purplish, and removing silt, after shining, a heatable brick bed is done, then removes fibrous root.[nature and flavor] are pungent, temperature.[return through] returns liver, gallbladder, pericardium channel.[function cures mainly] blood-activating and qi-promoting, wind-expelling pain-stopping.For menoxenia, amenorrhea dysmenorrhea, lump in the abdomen is suffered from abdominal pain, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia.[usage and dosage] takes orally: decoct soup, 9 ~ 25g.[attention] hyperactivity of fire caused by deficiency of YIN, upper excess and lower deficiency and the weak people of gas avoid clothes.[extracts] " China's book on Chinese herbal medicine ".
The Rhizoma Atractylodis Macrocephalae [another name] Rhizoma Atractylodis Macrocephalae, winter art, Zhejiang art, kind art.[source] this product is the dry rhizome of the feverfew Rhizoma Atractylodis Macrocephalae.Excavate when withered and yellow, the upper leaf of inferior leads in winter becomes fragile, removing silt, dries or dries, then remove fibrous root.[nature and flavor] are bitter, sweet, temperature.[return through] returns spleen, stomach warp.[function cures mainly] invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive.For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.Rhizoma Atractylodis Macrocephalae spleen invigorating, stomach function regulating, antiabortive.For insufficiency of the spleen lack of appetite, loose stool of having loose bowels, frequent fetal movement.[usage and dosage] takes orally: decoct soup, 6 ~ 12g.[attention] deficiency of YIN is yearningly dry, and stagnation of QI feeling of distension and oppression person avoids clothes.[extracts] " China's book on Chinese herbal medicine ".
Radix Notoginseng [another name] Radix Notoginseng, Yunnan seven, Radix Notoginseng, Radix Notoginseng.[source] is the tuber of araliaceae ginseng plant Radix Notoginseng, and its flower is also used as medicine.[nature and flavor] are sweet, bitter in the mouth, temperature.[return through] returns liver, stomach warp.[function cures mainly] tuber: activating blood and removing stasis, hemostasis, reducing swelling and alleviating pain.For epistaxis, spit blood, spitting of blood, have blood in stool, dysfunctional uterine hemorrhage, puerperal abdominal pain due to blood stasis, traumatic injury.Flower: heat clearing away, suppressing the hyperactive liver, blood pressure lowering.For acute pharyngolaryngitis, dizzy, dizzy, tinnitus.[usage and dosage] takes orally: decoct soup, 3 ~ 12g.[attention] blood deficiency tells nosebleed, and bleeding due to blood-heat person is forbidden.[extracts] " China's book on Chinese herbal medicine ".
The Rhizoma Pinelliae [another name] the SANYE Rhizoma Pinelliae, SANYE are old, three step jumpings, numb semen myristicae, swallow tail, civilian, water is beautiful.[source] this product is the dry tuber of the aroid Rhizoma Pinelliae.Summer, Qiu Erji excavate, and clean, and removing crust and fibrous root, dry.[nature and flavor] are pungent, temperature; Poisonous.[return through] returns spleen, stomach, lung meridian.[function cures mainly] drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass.For abundant expectoration cough with asthma, phlegm retention vertigo and palpitation, dizziness due to wind-phlegm, syncope due to accumulation of phlegm is had a headache, vomiting regurgitation, and breast gastral cavity painful abdominal mass is vexed, globus hystericus; Raw with external treatment carbuncle sucutaneous nodule.Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) is used for stopping nausea and vomiting by lowering the adverse flow of QI.[usage and dosage] takes orally: decoct soup, 3 ~ 9g.[attention] deficiency of YIN cough caused by dryness, Tianjin wound are thirsty, blood disorder and dry phlegm person prohibit clothes, the careful clothes of anemia of pregnant woman.Should not with Aconitum medical material with using.[extracts] " China's book on Chinese herbal medicine ".
Fructus Schisandrae Chinensis [another name] Wei, Chi Zhu, profound and, meeting and, five Fructus Armeniacae Mumes, Radix Schisandrae Bicoloris, FRUCTUS SCHISANDRAE from Liaoning of China.[source] this product is the dry mature fruit of magnoliaceae schisandra or schisandra chinensis.The former practises title " Radix Schisandrae Bicoloris ", and the latter practises title " Fructus Schisandrae Sphenantherae ".Pluck during fruit maturation in autumn, dry or dry after steaming, removing carpopodium and impurity.[nature and flavor] are sour, sweet, temperature.[return through] returns lung, the heart, kidney channel.[function cures mainly] restrains astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming.For chronic cough dyspnea due to deficiency, emission, enuresis frequent micturition, incessant chronic diarrhea, spontaneous perspiration, night sweat, Tianjin wound is thirsty, and deficient pulse of losing heart, interior-heat is quenched one's thirst, palpitation and insomnia.[usage and dosage] takes orally: decoct soup, 3 ~ 12g.Have pathogenic factor in the exterior outside [attention], inside have excess-heat, or cough from the beginning of, acute diseases such as cholera and sunstroke rash just originator avoid clothes.[extracts] " China's book on Chinese herbal medicine ".
Flos Carthami [another name] Flos Carthami.[source] this product is the dried floral of feverfew Flos Carthami.Pluck when summer, flower was red by xanthochromia and get tubular flower, note the ovary of not hindering base portion, removing impurity, dry in the shade or low baking temperature oven dry, now matter is softer, the red the best of color depth.(gather flower time, should to carry out time softer by not dry, the sharp thorn of bract of dew in morning as early as possible, but also too early unsuitable.）。[nature and flavor] are pungent, temperature.[return through] GUIXIN, Liver Channel.[function cures mainly] promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.For amenorrhea, dysmenorrhea, lochia, lump in the abdomen mass in the abdomen, injury from falling down, skin infection swells and ache.[usage and dosage] takes orally: decoct soup, 3 ~ 9g.[attention] anemia of pregnant woman is cautious use of.[extracts] " China's book on Chinese herbal medicine ".
Summary of the invention
The present invention aims to provide a kind of Chinese medicine being used for the treatment of angina pectoris, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing angina pectoris.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of Chinese medicine being used for the treatment of angina pectoris, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Fructus Trichosanthis 15 parts, Bulbus Allii Macrostemonis 10 parts, Radix Salviae Miltiorrhizae 10 parts, Rhizoma Chuanxiong 5 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, Radix Notoginseng 12 parts, the Rhizoma Pinelliae 12 parts, Fructus Schisandrae Chinensis 15 parts, 10 parts, Flos Carthami.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
Inventor in October, 2012 ~ 2013 collect outpatient service and hospitalized coronary artery disease patient with angina pectoris 60 example altogether between year October, be divided into treatment group 30 example and matched group 30 example at random, treatment group man 11 example, female 19 example, 42 ~ 66 years old age; Matched group man 12 example, female 18 example, 48 ~ 69 years old age.2 groups of sexes, age and course of disease comparing difference not statistically significants, have comparability.
Diagnostic criteria
Diagnostic criteria according to the meeting of national angina pectoris clinical speciality: the clinical manifestation of (1) coronary heart disease stable type angina pectoris patient: what occur suddenly is positioned at the squeezing after sternal body epimere or stage casing, vexed swollen property or asphyxiating pain, also most of pareordia can be involved, can be radiated to inside before left shoulder, left upper extremity, reach the third finger and little finger of toe.Its character is without changing in 1 ~ 3 month, and the course of disease, more than 1 month, is shown effect more than 2 times weekly, each lasting more than 3 minutes.(2) electrocardiogram: electrocardiogram have obvious myocardial ischemia and R ripple is dominant lead on have ischemic ST-segment to decrease beyond 0.05m V, or on normally not occurring that T ripple is inverted and leading, T ripple is inverted more than 2mm.
2, test method
2.1 Therapeutic Method
The capsule that the oral the present invention for the treatment of group obtains according to specific embodiment 3, every day 3 times.One month course for the treatment of.
Matched group oral administered compound loyal heart sheet, 3 pieces/times, 3 times/day.One month course for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
Clinic control: after treatment, angina pectoris classification reduces by 2 grades, and former I, II grade of person's angina pectoris disappear substantially, namely heavier exceed the physical exertion of daily routines time, also substantially there is not angina pectoris, do not need to take Nitrates medicine person;
Effective: after treatment, angina pectoris classification reduces by 1 grade, and former I level person angina pectoris disappears substantially, and Nitrates medicine subtracts uses person over half;
Invalid: after treatment, angina pectoris and Nitrates drug dose are without changing or reducing to some extent but do not reach significant degree person
Increase the weight of: angina pectoris attacks number of times after treatment, degree and persistent period exacerbate Nitrates medicine, consumption enhancer.
3.2 therapeutic outcomes are in table 1.
Table 1 liang group comparitive study
Visible, the medicine that the present invention obtains can safe and effective treatment angina pectoris, has promotional value.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Embodiment 1
Take: Fructus Trichosanthis 15 grams, Bulbus Allii Macrostemonis 10 grams, Radix Salviae Miltiorrhizae 10 grams, Rhizoma Chuanxiong 5 grams, the Rhizoma Atractylodis Macrocephalae 15 grams, Radix Notoginseng 12 grams, the Rhizoma Pinelliae 12 grams, Fructus Schisandrae Chinensis 15 grams, 10 grams, Flos Carthami; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 grams, must meet the decoct of adult normal's one day consumption.
Be used for the treatment of angina pectoris.Oral, every bu Morning Afternoon Evening is taken for three times.
Embodiment 2
Take: Fructus Trichosanthis 15 grams, Bulbus Allii Macrostemonis 10 grams, Radix Salviae Miltiorrhizae 10 grams, Rhizoma Chuanxiong 5 grams, the Rhizoma Atractylodis Macrocephalae 15 grams, Radix Notoginseng 12 grams, the Rhizoma Pinelliae 12 grams, Fructus Schisandrae Chinensis 15 grams, 10 grams, Flos Carthami; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's one day consumption.
Be used for the treatment of angina pectoris.Oral, every bu Morning Afternoon Evening is taken for three times.
Embodiment 3
Take: Fructus Trichosanthis 15 grams, Bulbus Allii Macrostemonis 10 grams, Radix Salviae Miltiorrhizae 10 grams, Rhizoma Chuanxiong 5 grams, the Rhizoma Atractylodis Macrocephalae 15 grams, Radix Notoginseng 12 grams, the Rhizoma Pinelliae 12 grams, Fructus Schisandrae Chinensis 15 grams, 10 grams, Flos Carthami; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, must meet the capsule of adult normal's one day consumption.
Be used for the treatment of angina pectoris.Oral, every bu Morning Afternoon Evening is taken for three times.
Claims (4)
1. one kind is used for the treatment of the Chinese medicine of angina pectoris, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Fructus Trichosanthis 15 parts, Bulbus Allii Macrostemonis 10 parts, Radix Salviae Miltiorrhizae 10 parts, Rhizoma Chuanxiong 5 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, Radix Notoginseng 12 parts, the Rhizoma Pinelliae 12 parts, Fructus Schisandrae Chinensis 15 parts, 10 parts, Flos Carthami.
2. be used for the treatment of the Chinese medicine of angina pectoris as claimed in claim 1, it is characterized in that, its preparation method is: take: Fructus Trichosanthis 15 parts, Bulbus Allii Macrostemonis 10 parts, Radix Salviae Miltiorrhizae 10 parts, Rhizoma Chuanxiong 5 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, Radix Notoginseng 12 parts, the Rhizoma Pinelliae 12 parts, Fructus Schisandrae Chinensis 15 parts, 10 parts, Flos Carthami; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 parts, obtains decoct; Above-mentioned part all refers to weight portion.
3. be used for the treatment of the Chinese medicine of angina pectoris as claimed in claim 1, it is characterized in that, its preparation method is: take: Fructus Trichosanthis 15 parts, Bulbus Allii Macrostemonis 10 parts, Radix Salviae Miltiorrhizae 10 parts, Rhizoma Chuanxiong 5 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, Radix Notoginseng 12 parts, the Rhizoma Pinelliae 12 parts, Fructus Schisandrae Chinensis 15 parts, 10 parts, Flos Carthami; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, obtains powder; Above-mentioned part all refers to weight portion.
4. be used for the treatment of the Chinese medicine of angina pectoris as claimed in claim 1, it is characterized in that, its preparation method is: take: Fructus Trichosanthis 15 parts, Bulbus Allii Macrostemonis 10 parts, Radix Salviae Miltiorrhizae 10 parts, Rhizoma Chuanxiong 5 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, Radix Notoginseng 12 parts, the Rhizoma Pinelliae 12 parts, Fructus Schisandrae Chinensis 15 parts, 10 parts, Flos Carthami; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, obtains capsule; Above-mentioned part all refers to weight portion.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510175232.5A CN104740216A (en) | 2015-04-15 | 2015-04-15 | Traditional Chinese medicine for treating coronary heart disease and stenocardia |
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| CN201510175232.5A CN104740216A (en) | 2015-04-15 | 2015-04-15 | Traditional Chinese medicine for treating coronary heart disease and stenocardia |
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| CN201510175232.5A Withdrawn CN104740216A (en) | 2015-04-15 | 2015-04-15 | Traditional Chinese medicine for treating coronary heart disease and stenocardia |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105055845A (en) * | 2015-09-17 | 2015-11-18 | 南京正亮医药科技有限公司 | Medicine preparation for treating cardiac insufficiency |
| CN105853908A (en) * | 2016-04-15 | 2016-08-17 | 宁波优美科新材料有限公司 | Medicine for treating angina |
| CN105998567A (en) * | 2016-06-21 | 2016-10-12 | 牡丹江医学院红旗医院 | Traditional Chinese medicinal liquor for treating stenocardia and preparation method thereof |
-
2015
- 2015-04-15 CN CN201510175232.5A patent/CN104740216A/en not_active Withdrawn
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105055845A (en) * | 2015-09-17 | 2015-11-18 | 南京正亮医药科技有限公司 | Medicine preparation for treating cardiac insufficiency |
| CN105853908A (en) * | 2016-04-15 | 2016-08-17 | 宁波优美科新材料有限公司 | Medicine for treating angina |
| CN105998567A (en) * | 2016-06-21 | 2016-10-12 | 牡丹江医学院红旗医院 | Traditional Chinese medicinal liquor for treating stenocardia and preparation method thereof |
| CN105998567B (en) * | 2016-06-21 | 2019-11-26 | 牡丹江医学院红旗医院 | Treat anginal Traditional Chinese medicinal liquor and preparation method thereof |
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Application publication date: 20150701 |