CN104739871A - Non-odor processing method for earthworms - Google Patents

Non-odor processing method for earthworms Download PDF

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Publication number
CN104739871A
CN104739871A CN201510096307.0A CN201510096307A CN104739871A CN 104739871 A CN104739871 A CN 104739871A CN 201510096307 A CN201510096307 A CN 201510096307A CN 104739871 A CN104739871 A CN 104739871A
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China
Prior art keywords
pheretima
milk
processing method
dry
free
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Pending
Application number
CN201510096307.0A
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Chinese (zh)
Inventor
赵建东
何军
周冉
冯巧巧
田原
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Jinan Kangzhong Pharmaceutical Research and Development Co Ltd
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Jinan Kangzhong Pharmaceutical Research and Development Co Ltd
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Application filed by Jinan Kangzhong Pharmaceutical Research and Development Co Ltd filed Critical Jinan Kangzhong Pharmaceutical Research and Development Co Ltd
Priority to CN201510096307.0A priority Critical patent/CN104739871A/en
Publication of CN104739871A publication Critical patent/CN104739871A/en
Pending legal-status Critical Current

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  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

The invention relates to a non-odor processing method for earthworms. The non-odor processing method is characterized in that milk is added in a processing process. The earthworms processed by the invention are high in activity, small in peculiar smell while being orally taken, good in mouthfeel and high in compliance for a patient.

Description

The processing method of a kind of free from extraneous odour Pheretima
Invention field
The present invention relates to medicine, particularly the processing method of a kind of free from extraneous odour Pheretima, belong to medical art.
Background technology
Pheretima is the dry body of Annelida Ju Yin section animal Pheretima aspergillum, popular Pheretimatschiliensis, power simulation or comb the region between the heart and the diaphragm hair earthworm.Front one is practised and is claimed " LUMBRICUS ", practises title " Lu Pheretima " for latter three kinds.LUMBRICUS catches to autumn spring, and Lu Pheretima catches summer, cuts abdominal part open in time, and removing internal organs and silt are cleaned, dried or cold drying;
Pheretima has heat clearing away arresting convulsion, dredging collateral, relievings asthma, effect of diuresis.For unconsciousness due to high fever, frightened carbuncle is twitched, and joint is benumbed, numb limbs and tense tendons, hemiplegia, dyspnea and cough due to lung-heat, edema oliguria etc.Modern study finds that Pheretima also has the effect such as antithrombotic, antitumor, immunity moderation, blood pressure lowering, arrhythmia, easing pain and diminishing inflammation.
Pheretima powder warm water is taken after mixing it with water, and abnormal flavour is extra heavy, and mouthfeel is very poor, directly affects the compliance of patient.A kind of method improving Pheretima powder mouthfeel is provided, very necessary.
Summary of the invention
The object of this invention is to provide the processing method of a kind of free from extraneous odour Pheretima.
The object of the present invention is achieved like this:
A processing method for free from extraneous odour Pheretima, is characterized in that: the course of processing adds milk.
The processing method of a kind of free from extraneous odour Pheretima of the present invention, is characterized in that: the Pheretima alive of seizure cuts abdominal part open in time, removing internal organs and silt, cleans, dry after adding milk.
The processing method of a kind of free from extraneous odour Pheretima of the present invention, is characterized in that: the amount adding milk is Xian Di Long ︰ milk=1 ︰ 0.5-10 by weight.
So far the present invention is completed.The Pheretima of the present invention's processing, active high, oral abnormal flavour is little, and mouthfeel is good, and the compliance of patient is high.
Below by test example, usefulness of the present invention is described.Test example is intended to further illustrate beneficial effect of the present invention below, but not restriction of the present invention.
Test example one, different processing methods mouthfeel compare
1, by same mass products Pheretima, process by the following method.
1) dry: cut abdominal part open, removing internal organs and silt, clean, less than 60 DEG C oven dry, pulverize;
2) add milk to dry: cut abdominal part open, removing internal organs and silt, clean, add the milk of 0.5 times by weight, less than 60 DEG C oven dry, pulverize.
2, mouthfeel evaluation is made up of 10 people and appraises group through discussion, and everyone warm water for oral use oven dry of mixing well and add the Pheretima powder that milk dries respectively, evaluates the mouthfeel concept such as " very well ", " better ", " can accept ", " poor ", " very poor ".The results are shown in Table 1
The Pheretima powder mouthfeel of table 1 different processing methods compares
Very well Better Can accept Poor Very poor
Add milk to dry 0 people 2 people 8 people 0 people 0 people
Dry 0 people 0 people 0 people 4 people 6 people
Result shows, and the Pheretima course of processing adds milk, and oral abnormal flavour is little, and mouthfeel is good.
The Pheretima antiasthmatic effect of test example two, different processing methods compares
1, by same mass products Pheretima, process by the following method.
1) dry: cut abdominal part open, removing internal organs and silt, clean, less than 60 DEG C oven dry, pulverize;
2) add milk to dry: cut abdominal part open, removing internal organs and silt, clean, add the milk of 2 by weight, less than 60 DEG C oven dry, pulverize.
2, the different instructions of taking antiasthmatic effect of Pheretima powder compares
Acetylcholine draws to be breathed heavily test and chooses weight 200-250 g Cavia porcellus, puts respectively in automiser spray, sprays into containing 1mg/ml acecoline solution with soniclizer with same intensity, and spraying 15s Cavia porcellus, through one period of incubation period, produces asthma.Will not selecting of asthma is not produced more than 60 s.Then 3 groups are divided at random, often organize 10, be respectively negative control group normal saline 10 ml/kg, with oven dry Pheretima powder group (0.35 g/kg), add milk oven dry group (0.35 g/ kg, with Pheretima content meter), each group of equal gastric infusion, mixing well volume with normal saline is 10m1/kg, after administration 30min, put into sprayer unit respectively and spray into acecoline solution respectively by preliminary election similarity condition, record spraying starts to the time that symptoms of asthma occurs as latent time, observe 3min, the asthmatic latent period without asthma calculates with 3min.The results are shown in Table 2.
The Pheretima antiasthmatic effect of table 2 different processing methods compares
Negative control group Add milk to dry Dry
Dosage 0 0.35g/kg 0.35g/kg
Incubation period (s) 54±6 85±7 75±8
Result shows, Pheretima powder has good antiasthmatic effect, and adds milk and dry Pheretima and be better than the Pheretima of oven dry.
The Pheretima anticoagulation test of test example three, distinct methods processing
1, by same mass products Pheretima, process by the following method.
1) dry: cut abdominal part open, removing internal organs and silt, clean, less than 60 DEG C oven dry, pulverize;
2) add milk to dry: cut abdominal part open, removing internal organs and silt, clean, add the milk of 3 by weight, less than 60 DEG C oven dry, pulverize.
2, the Pheretima anticoagulation test of distinct methods processing
1) preparation of Pheretima extract: Pheretima adds 20 times amount water soaking 12h, decocts 2 times, the 1st 2h, and the 2nd 1.5h merges 2 decocting liquids, be evaporated to every milliliter of medicinal liquid and be equivalent to 1g Pheretima, obtain Pheretima extract.
2) Pheretima extract is on the impact of clotting time of mice: mice 30, then 3 groups are divided at random, often organize 10, be respectively negative control group reason saline 10 ml/kg, administration group gives Pheretima extract 10 ml/kg respectively, and successive administration 3d measures clotting time by capillary glass-tube method after last administration 30min.The results are shown in Table 3.
The Pheretima anticoagulant effect of table 3 distinct methods processing compares
Negative control group Add milk to dry Dry
Dosage 0 10g/ kg 10g/ kg
Clotting time (s) 102±12 162±17 125±14
Result shows, adds the Pheretima anticoagulant effect of milk oven dry apparently higher than the Pheretima of drying.
Detailed description of the invention
A processing method for free from extraneous odour Pheretima, is characterized in that: the course of processing adds milk.
The processing method of a kind of free from extraneous odour Pheretima powder of the present invention, is characterized in that: the Pheretima alive of seizure cuts abdominal part open in time, removing internal organs and silt, cleans, dry after adding milk.
The processing method of a kind of free from extraneous odour Pheretima of the present invention, is characterized in that: the amount adding milk is Xian Di Long ︰ milk=1 ︰ 0.5-10 by weight.
embodiment 1
The Pheretima that lives cuts abdominal part open, and removing internal organs and silt are cleaned, and pure land dragon 5kg, adds milk 2.5kg, less than 60 DEG C oven dry.Make powder, oral free from extraneous odour.
embodiment 2
The Pheretima that lives cuts abdominal part open, and removing internal organs and silt are cleaned, and pure land dragon 5kg, adds milk 50kg, less than 60 DEG C oven dry.Make powder, oral free from extraneous odour.
embodiment 3
The Pheretima that lives cuts abdominal part open, and removing internal organs and silt are cleaned, and pure land dragon 5kg, puts into 5kg milk, together put in freeze dryer, be refrigerated to less than-10 DEG C, be evacuated to below drying chamber pressure 30Pa, subliming by heating; The temperature of distillation should control below 40 DEG C, and the temperature of resolution phase controls below 45 DEG C, to dry.Make powder, oral free from extraneous odour.
embodiment 4
The Pheretima that lives cuts abdominal part open, and removing internal organs and silt are cleaned, and pure land dragon 5kg, adds milk 3kg, dry.Make powder, oral free from extraneous odour.
embodiment 5
The Pheretima that lives cuts abdominal part open, and removing internal organs and silt are cleaned, and pure land dragon 5kg, adds milk 20kg, less than 60 DEG C drying under reduced pressure.Make powder, oral free from extraneous odour.
embodiment 6
The Pheretima that lives cuts abdominal part open, and removing internal organs and silt are cleaned, and pure land dragon 5kg, puts into 10kg milk, together lyophilizing.Make powder, oral free from extraneous odour.

Claims (3)

1. a processing method for free from extraneous odour Pheretima, is characterized in that: the course of processing adds milk.
2. the processing method of a kind of free from extraneous odour Pheretima according to claim 1, is characterized in that: the Pheretima alive of seizure cuts abdominal part open in time, removing internal organs and silt, cleans, dry after adding milk.
3. the processing method of a kind of free from extraneous odour Pheretima according to claim 1, is characterized in that: the amount adding milk is Xian Di Long ︰ milk=1 ︰ 0.5-10 by weight.
CN201510096307.0A 2015-03-05 2015-03-05 Non-odor processing method for earthworms Pending CN104739871A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201510096307.0A CN104739871A (en) 2015-03-05 2015-03-05 Non-odor processing method for earthworms

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Application Number Priority Date Filing Date Title
CN201510096307.0A CN104739871A (en) 2015-03-05 2015-03-05 Non-odor processing method for earthworms

Publications (1)

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CN104739871A true CN104739871A (en) 2015-07-01

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1748718A (en) * 2005-10-20 2006-03-22 北京润德康医药技术有限公司 Fresh earthworm preparation with the functions of calming the liver and relieving convulsion, promoting blood circulation and removing obstruction in channels and its preparing method
CN103891895A (en) * 2012-12-31 2014-07-02 内蒙古伊利实业集团股份有限公司 Liquid dairy product containing earthworm protein and preparation method of liquid dairy product

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1748718A (en) * 2005-10-20 2006-03-22 北京润德康医药技术有限公司 Fresh earthworm preparation with the functions of calming the liver and relieving convulsion, promoting blood circulation and removing obstruction in channels and its preparing method
CN103891895A (en) * 2012-12-31 2014-07-02 内蒙古伊利实业集团股份有限公司 Liquid dairy product containing earthworm protein and preparation method of liquid dairy product

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