CN1047205A - The manufacture method of tinea medicine - Google Patents
The manufacture method of tinea medicine Download PDFInfo
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- CN1047205A CN1047205A CN 89103248 CN89103248A CN1047205A CN 1047205 A CN1047205 A CN 1047205A CN 89103248 CN89103248 CN 89103248 CN 89103248 A CN89103248 A CN 89103248A CN 1047205 A CN1047205 A CN 1047205A
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- tinea
- medicine
- chinese
- tincture
- formaldehyde
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- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Tinea medicine is a kind of treatment tinea corporis, and dermopathic combination of Chinese and Western medicine preparation such as tinea imbricata belongs to tincture.It is formed by ethanol, water, Chinese medicine, chemical substance manufacturing, contains active carbonyl in its composition.These product are generally only put on the skin once, just can fully recover.Can not only be antibacterial, again can kill fungi, virus, brood cell, the convergence that has Chinese medicine concurrently is antipruritic, the effect of heat-clearing and toxic substances removing.
Description
Tinea medicine is a kind of dermopathic combination of Chinese and Western medicine preparations such as ulcer for the treatment of tinea corporis, tinea imbricata, tinea cruris, insect dermatitis and unknown cause; Belong to tincture.It all is the medicine that Chinese Pharmacopoeia is put down in writing that prescription constitutes.That this product does not contain is female, plumbous, hydrargyrum and deleterious material.Identify the sanitary index conformance with standard by the toxicity curative effect.This product and will putting on market in large quantity.
Dermopathic pharmaceutical dosage forms such as treatment tinea corporis, tinea imbricata have tincture, powder, unguentum both at home and abroad at present.Fundamental component can be divided into several classes:
Organic acid: salicylic acid (comprising methyl salicylate, N-phenylsalicylamide), benzoic acid, undecylenic acid, glacial acetic acid etc.Salicylic mechanism has antifungic action, and skin, mucosa are had stimulation; 3～6% treatment dermatomycosiss, 10～25% concentrated solutions horny layer of loosening.
Phenols: phenol (carbolic acid), cresol, resorcinol (resorcin).Phenols causes protein denaturization, precipitation and endochylema permeability changes, has to suppress and bactericidal action.
Antibiotics class: gram azoles mycin etc.
Chinese herbal medicine class: Borneolum Syntheticum, Camphora, Radix Sophorae Flavescentis, Fructus Cnidii, Cortex Pseudolaricis, Cortex Dictamni etc.
Minerals: sulfur, Lithargyrum, Calomelas, arsenicum sablimatum, hydrargyrum etc.
Hormones: prednisone, andrographolide, triamcinolone, fludrocortisone acetate etc.
Other class: dimethyl sulfoxide, iodine etc.
The medicine of being made by top composition kills strong tinea water (Guangzhou) black and white ringworm medicine (Changzhou, Wuxi), skin ringworm medicine (Guangdong) medicine for treating tinea (Jiangxi), econazole (Tianjin) and kills strong tinea cream (Hubei) tinea ointment (Tianjin) fluocinonide (Tianjin) triamcinolone ointment (Hubei) etc.
Dermopathic medicines such as the treatment tinea corporis that countries in the world produce, tinea imbricata have some weak point
1, the patient needs to put on the skin every day three times, and several days is a course of treatment, course of disease length, weak effect, recurrence easily.
2, dermatophytes only there is inhibitory action.
3, tincture is big to skin irritation, and the unguentum greasy feeling is strong, dirty linen; Powder uses trouble.
This invention has added formaldehyde in manufacture process, make to contain active carbonyl in the solution, formaldehyde can with proteinic amino the combination, changed the function of peptide chain, make protein denaturation precipitation, can kill fungi, virus, brood cell etc.Simultaneously, compare, reduced salicylic acid, the benzoic acid consumption with medicine of the same race.Increased by one group of heat clearing and damp drying in the prescription again, the antipruritic tinea of going out, the parasite killing granulation promoting, the Chinese medicine of skin ulcer is treated in detoxifcation.
The tinea medicine of manufacturing of the present invention has three advantages.
1, these product are only put on the skin once, just can recovery from illness, short treating period, usage be simple, changed traditional medicine for external use and put on the skin three times every day, and several days is the method for a course of treatment.
2, these product can not only be antibacterial, and the energy kill fungi, virus, brood cell.The convergence that has Chinese medicine again concurrently is antipruritic, the effect of heat-clearing and toxic substances removing.
3, this product zest is little, and clean hygiene is nontoxic to human body, does not contain harmful substances such as female, plumbous, hydrargyrum.
Embodiment:
The raw material that is equipped with agent before making, with per 10, the cubage of 000mL medicinal liquid:
Cortex Phellodendri 100～500 grams are early stopped 100～500 grams
Radix Sophorae Flavescentis 100～500 gram Radix Trichosanthis 50～300 grams
Cortex Pseudolaricis 100～500 gram salicylic acid 50～500 grams
Fructus Cnidii 50～300 gram benzoic acid 100～1000 grams
Cortex Dictamni 50～300 gram Camphoras 50～300 grams
Rhizoma Atractylodis 50～300 gram formaldehyde 55.1mL～525mL
The Radix Angelicae Dahuricae 100～600 grams 50～85% ethanol 10,000～15000mL
The Fructus Kochiae 50～200 gram essence are an amount of
Operating process:
1, the ethanol of preparation dilute concentration
2, Chinese medicine is packed in certain container, soaked for ten flavor Chinese medicine 3～30 days or longer times, extract active ingredient with infusion process with Diluted Alcohol.Make tincture.Also can divide secondary or extract wherein composition three times, reach the amount of regulation after the mixing.
3, salicylic acid, benzoic acid, Camphora are added and contains in the tincture of Chinese medicinal ingredients, make dissolving.
4, add formaldehyde, stirring again.
5, add essence with correct abnormal smells from the patient and.
(indicate: tinea medicine be " one-time efficacious " series of products 1V, and medicine name be " one-time efficacious " tinea medicine, and the cosmeceutical name is called " one-time efficacious " skin toner tinea perfume dew that goes out).
Claims (2)
1, the method for the tincture of diseases such as a kind of treatment tinea corporis, tinea imbricata, tinea cruris, insect dermatitis by formaldehyde, salicylic acid, other medicines manufacturing, its step is as follows:
(1) ethanol of preparation dilute concentration.
(2) be mixed with tincture with formaldehyde, salicylic acid, other medicines.
2, according to the method for claims 1, having added concentration in manufacture process is the formaldehyde of 0.2%g/ml～2%g/mL.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 89103248 CN1047079C (en) | 1989-05-13 | 1989-05-13 | Process for preparing tinea medicine |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 89103248 CN1047079C (en) | 1989-05-13 | 1989-05-13 | Process for preparing tinea medicine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1047205A true CN1047205A (en) | 1990-11-28 |
| CN1047079C CN1047079C (en) | 1999-12-08 |
Family
ID=4855046
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 89103248 Expired - Fee Related CN1047079C (en) | 1989-05-13 | 1989-05-13 | Process for preparing tinea medicine |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1047079C (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1057449C (en) * | 1994-03-01 | 2000-10-18 | 刘海峰 | Medicine for tinea |
| CN102688429A (en) * | 2012-06-08 | 2012-09-26 | 王建国 | Medicinal tincture for treating fungal diseases |
| CN103070960A (en) * | 2013-02-01 | 2013-05-01 | 吉林农业大学 | External medicine linimentum for treating equus mange and preparation method of external medicine linimentum |
-
1989
- 1989-05-13 CN CN 89103248 patent/CN1047079C/en not_active Expired - Fee Related
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1057449C (en) * | 1994-03-01 | 2000-10-18 | 刘海峰 | Medicine for tinea |
| CN102688429A (en) * | 2012-06-08 | 2012-09-26 | 王建国 | Medicinal tincture for treating fungal diseases |
| CN103070960A (en) * | 2013-02-01 | 2013-05-01 | 吉林农业大学 | External medicine linimentum for treating equus mange and preparation method of external medicine linimentum |
| CN103070960B (en) * | 2013-02-01 | 2014-07-09 | 吉林农业大学 | External medicine linimentum for treating equus mange and preparation method of external medicine linimentum |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1047079C (en) | 1999-12-08 |
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| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C15 | Extension of patent right duration from 15 to 20 years for appl. with date before 31.12.1992 and still valid on 11.12.2001 (patent law change 1993) | ||
| OR01 | Other related matters | ||
| C19 | Lapse of patent right due to non-payment of the annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |