CN104689484A - LED physiotherapy instrument for treating allergic rhinitis and application method thereof - Google Patents
LED physiotherapy instrument for treating allergic rhinitis and application method thereof Download PDFInfo
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- CN104689484A CN104689484A CN201510072352.2A CN201510072352A CN104689484A CN 104689484 A CN104689484 A CN 104689484A CN 201510072352 A CN201510072352 A CN 201510072352A CN 104689484 A CN104689484 A CN 104689484A
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Abstract
The invention provides an LED physiotherapy instrument for treating allergic rhinitis and an application method thereof. The LED physiotherapy instrument is applied to physical treatment of allergic rhinitis. The instrument comprises a power supply, a controller, an LED matrix, and a flexible carrier capable of replacing the LED matrix; the power supply, the controller and the LED matrix are all mounted on the flexible carrier capable of replacing the LED matrix; the LED matrix is mounted at the inner side of the flexible carrier capable of replacing the LED matrix and directly faces cervical vertebra; the power supply and the controller are mounted at the outer side of the flexible carrier capable of replacing the LED matrix and are back to the cervical vertebra; the power supply, the controller and the LED matrix are sequentially connected through conductive wires. With the adoption of the instrument, the symptom of allergic rhinitis can be reduced, the asthma can be prevented, and the allergic disease prognosis can be avoided.
Description
Technical field
The present invention relates to a kind of LED physiotherapy table for allergic rhinitis treatment, be applied to the naturopathy of allergic rhinitis.
Background technology
Allergic rhinitis (AR) is called for short allergic rhinitis or allergic rhinitis, be after atopic individuals contact sensitinogen by IgE mediate be released to the beginning with inflammatory mediator (mainly histamine), the nasal mucosa chronic inflammatory reaction disease that has immunologically competent cell and proinflammatory cytokines (pro-inflammatory cells) and cytokine (cytokines) etc. to participate in.
Allergic rhinitis are modal types in rhinitis.That in various anaphylactic disease, sickness rate is the highest.Allergic rhinitis prevalence obviously increases nearly ten years, approximately has influence on the crowd in the whole world 10% ~ 25%, especially higher in the national prevalence that industry is flourishing.Allergic rhinitis morbidity increase may with SO in atmospheric pollution, air
2concentration increases, the life style of the change of dietary structure and " excessively clean " is relevant, also may accelerate with economic development, process of industrialization, lifestyle change is relevant.
Although AR can not threat to life, can affect quality of life, cause the financial burden of individual and society, therefore child can have influence on school grade, and obstructive sleep respiratory disorder appears in severe patient, even has influence on Maxillary region and grows.The patients with rhinitis of 30%-40% has asthma, and the asthmatic patient of 60%-70% has rhinitis, and the probability that patients with rhinitis obtains asthma increases by 3 times.Thus correct diagnosis, it is particularly important that effective remedy measures and prevention just show.
Allergic rhinitis morbidity has two stages: 1. sensitization: sensitinogen (allergen) enters nasal cavity, is caught processing by the antigen presenting cell in nasal mucosa, and by antigenic peptides submission to T cells, T cell differentiation makes its increasing number to Th2 skew.Th2 emiocytosis IL-4, the latter acts on B cell makes it be converted to plasma cell, and produces IgE.IgE borrows its receptor Fc ε RI on mastocyte or basophilic leukocyte surface and Fc ε RII and is combined on these two kinds of cells.This stage is sensitisation phase.2. excite: when allergen enters nasal cavity again, just can inspire the clinical symptoms of allergic rhinitis and the inflammatory reaction of nasal mucosa.This one-phase is divided into again.
Early send out phase (early phase): occur with in several minutes of allergen contact.Inflammatory mediator primarily of mastocyte/basophilic leukocyte retting conditions release causes.Two adjacent IgE bridgings on allergen and mastocyte/basophilic leukocyte surface, produce signal, cause calcium ion to enter cell, activated protein kinase C, make intracellular granular memebrane protein phosphorylation, by pre-synthesis and be stored at intracellular inflammatory mediator such as histamine etc. and discharged by retting conditions.Now inducing cell membrane phospholipid medium synthesis again, as arachidonic acid metabolite (prostaglandin, leukotriene).These media act on the sensory nerve ending of nasal mucosa, blood vessel wall and body of gland, just create the sniffle early sending out phase: multiple sneeze, rhinorrhea and nasal obstruction.
Evening sends out phase (late phase): betide and early send out 4 ~ 6h mutually, mainly being caused the mucosal inflammation of inflammatory cell infiltration by cytokine, is also the main cause that local inflammation is delayed.The cytokine signaling (IL-4, IL-5, IL-13, GM-CSF) of Th2 cell, epithelial cell, fibroblast release acts on bone marrow, causes eosinophil differentiation, maturation, moves chemotactic to nasal mucosa, and at local cluster.Same mastocyte, eosinophilic granulocyte and epithelial cell also secrete multiple proinflammatory cytokine (proinflammatory cytokines) and chemotactic factor (chemokines), the infiltration of further promotion eosinophilic granulocyte in local, to gather, and make its life span extension.The toxic protein of eosinophilic granulocyte's release causes nasal mucosa damage again, has increased the weight of the inflammatory reaction of local.
The treatment of allergic rhinitis generally comprises avoids contact allergen, Drug therapy, immunotherapy and operative therapy etc.Allergic rhinitis occur together chronic nasal obstruction, concha nasalis inferior adenoid, loose time can consider operation.Have no physical method treatment.
Summary of the invention
The present invention is directed to the deficiency of existing medical skill, a kind of LED physiotherapy table of pure physics immunization therapy allergic rhinitis is provided.
Another object of the present invention is to provide a kind of using method of the LED physiotherapy table for allergic rhinitis treatment.
The theoretical basis of technical solution of the present invention is as follows.
630nm ~ 750nm near-infrared wavelength section LED light treats cervical vertebra, body T cell can be induced to break up allergic constitution patient and make its quantity and Th2 relative equilibrium to Th1 skew, the IFN-γ that Th1 produces blocks IgE synthesis, lower SERUM IgE total amount, directly block irritated biological chain from immune root, have good inhibitory action to immediate hypersensitivity, thus strengthen immunologic tolerance, the symptoms such as effective alleviation rhinocnesmus, sneeze and watery nasal discharge, can the development of prevention of allergic diseases.
The object of the invention is to be achieved by the following technical programs.
A kind of LED physiotherapy table for allergic rhinitis treatment, comprise the flexible carrier of power supply, controller, LED matrix and replaceable LED matrix, described power supply, controller, LED matrix are installed on the flexible carrier of replaceable LED matrix, just to cervical vertebra place inside the flexible carrier that LED matrix is arranged on replaceable LED matrix, back to cervical vertebra place outside the flexible carrier that power supply and controller are arranged on replaceable LED matrix, power supply, controller, LED matrix are connected successively by conductor wire.
The flexible carrier two ends of described replaceable LED matrix are provided with magic hasps.
Described controller is provided with controller connecting terminal, and is furnished with the remote controller matched with controller connecting terminal.
The pulse generating circuit, clock circuit and the drive circuit that are connected to each other is comprised in controller, power supply is connected with pulse generating circuit, clock circuit and drive circuit respectively, clock circuit is connected with pulse generating circuit, and pulse generating circuit is connected with drive circuit, and drive circuit is connected with LED matrix.
Described pulse generating circuit, clock circuit and drive circuit can be made up of integrated circuit and discrete component, also all can form corresponding circuit by discrete component.Described power supply can be accumulator, also can be that power supply adaptor is connected with controller by electric lead.
Described pulse generating circuit, produce the pulse frequency of 0.2-20 KHz per second, dutycycle is at 15-95% continuously adjustabe.
Described clock circuit provides time standard and whole equipment starts, the time controling of stopping.
Described LED matrix is made up of the infrarede emitting diode of flexible printed circuit board and two groups of different wave lengths, the infrarede emitting diode intersection of described two groups of different wave lengths is connected into a near infrared light flexible light stripe, is arranged on flexible printed circuit board with another near infrared light flexible light stripe parallel connected array.
The wavelength of described infrarede emitting diode is from 630nm-780 nm.
Described LED matrix is made up of the near-infrared luminous diode of two groups of different wave lengths, is the LED of 630nm and 660nm or 660nm and 730nm.
Described LED matrix average light illumination is 5-25mW/cm2.
Described flexible carrier is integrally formed with LED matrix, two kinds of different wave lengths combination flexible printed circuit board and flexible carrier in conjunction with time can mutually change, during use, LED matrix can be close to ceruical uertebra part skin surface with the dynamics of 5-10g/cm2 by described flexible carrier.
Described LED matrix flexible carrier is made up of natural, artificial fabric and charges.
For a LED physiotherapy table for allergic rhinitis treatment, it is characterized in that treating for allergic rhinitis.
Beneficial effect of the present invention: the release of inflammatory mediator that the present invention can effectively suppress anaphylactogen to mediate, the persistence of nasal mucosa chronic inflammatory reaction disease having immunologically competent cell and proinflammatory cytokines etc. to participate in are in progress, significantly improve the symptom of allergic rhinitis and the prognosis of anaphylactic disease, also can be used for treatment flu and anaphylactic disease.Due to the combination of the distinctive LED different wavelengths of light of the present invention, Allergic Rhinitis is when carrying out phototherapy, the incoherent laser irradiation cervical vertebra of infrared pulse, through in skin ingress engine soma and blood, promote that Th2-Th1 transforms, increase the Th-1 cell of activation, prevent IgE from breeding, avoid single anaphylactogen irritated to the conversion of multiple anaphylactogen allergy, significantly can improve the symptom of allergic rhinitis, the generation of prevention of asthma disease and the prognosis of anaphylactic disease.This unexpected effect result in a kind of effective allergic rhinitis physical therapy modalities.
The present invention adopts the single-frequency spectral matrix illuminance being no more than 25mW/cm2, and far below the solar illuminance (50mW/cm2) of corresponding light spectral coverage, its clinical safety is protected.Clinical practice is simple and convenient and economical.Dissimilar to the many cases so far Allergic Rhinitis of the present invention has carried out product clinical trial of the present invention, result shows that experimental prototype of the present invention all has good clinical manifestation for dissimilar allergic rhinitis, clinical trial confirm Allergic Rhinitis phototherapy after three days quantity of leucocyte obviously promote, comparatively before treatment, clinical symptoms takes an evident turn for the better, and relapse rate obviously reduces, through treatment one to two course for the treatment of (seven days each courses for the treatment of), anaphylactogen no longer can cause allergic rhinitis in three months, other medicines are not needed to participate in auxiliary treatment during treatment, it is a kind of effective pure physics immunotherapy method.
Accompanying drawing explanation
Fig. 1 is outboard structure schematic diagram of the present invention.
Fig. 2 is inside structure schematic diagram of the present invention.
Fig. 3 is controller circuitry schematic diagram of the present invention.
In figure, 1 power supply, 2 controllers, 3 controller connecting terminals, the flexible carrier of 4 replaceable LED matrixes, 5 magic hasps, 6 LED matrixes.
Detailed description of the invention
Below in conjunction with accompanying drawing, the present invention will be further described in detail.
embodiment one.
A kind of LED physiotherapy table for allergic rhinitis treatment, comprise power supply (1), controller (2), the flexible carrier (4) of LED matrix (6) and replaceable LED matrix, described power supply (1), controller (2), LED matrix (6) is installed on the flexible carrier (4) of replaceable LED matrix, LED matrix (6) is arranged on flexible carrier (4) inner side of replaceable LED matrix just to cervical vertebra place, power supply (1) and controller (2) are arranged on flexible carrier (4) outside of replaceable LED matrix back to cervical vertebra place, power supply (1), controller (2), LED matrix (6) is connected successively by conductor wire.Flexible carrier (4) two ends of described replaceable LED matrix are provided with magic hasps (5).
Described controller (2) is provided with controller connecting terminal (3), and is furnished with the remote controller matched with controller connecting terminal (3).
The pulse generating circuit, clock circuit and the drive circuit that are connected to each other is comprised in controller (2), power supply (1) is connected with pulse generating circuit, clock circuit and drive circuit respectively, clock circuit is connected with pulse generating circuit, pulse generating circuit is connected with drive circuit, and drive circuit is connected with LED matrix (6).
Described pulse generating circuit, clock circuit and drive circuit can be made up of integrated circuit and discrete component.Described power supply is accumulator.
Described pulse generating circuit, produce the pulse frequency of 0.2 KHz per second, dutycycle is adjusted to 95%.
Described clock circuit provides time standard and whole equipment starts, the time controling of stopping.
Described LED matrix (6) is made up of the infrarede emitting diode of flexible printed circuit board and two groups of 630nm and 660nm wavelength, the infrarede emitting diode intersection of described two groups of wavelength is connected into a near infrared light flexible light stripe, is arranged on flexible printed circuit board with another near infrared light flexible light stripe parallel connected array.
Described LED matrix average light illumination is 5-25mW/cm2.During use, LED matrix can be close to ceruical uertebra part skin surface with the dynamics of 5-10g/cm2 by described flexible carrier.
Described LED matrix flexible carrier is made up of natural, artificial fabric and charges.
Experimenter A, suffers from the allergic rhinitis of Inheritance, and use LED physiotherapy table two days later, total white blood cells is by 6.2 × 10
9/ L brings up to 7.2 × 10
9/ L, after five days, total white blood cells is 7.96 × 10
9/ L, after seven days, total white blood cells is 6.8 × 10
9/ L, clinical symptoms is clearly better.
embodiment two.
A kind of LED physiotherapy table for allergic rhinitis treatment, comprise power supply (1), controller (2), the flexible carrier (4) of LED matrix (6) and replaceable LED matrix, described power supply (1), controller (2), LED matrix (6) is installed in (4) on the flexible carrier of replaceable LED matrix, LED matrix (6) is arranged on flexible carrier (4) inner side of replaceable LED matrix just to cervical vertebra place, power supply (1) and controller (2) are arranged on flexible carrier (4) outside of replaceable LED matrix back to cervical vertebra place, power supply (1), controller (2), LED matrix (6) is connected successively by conductor wire.Flexible carrier (4) two ends of described replaceable LED matrix are provided with magic hasps (5).
Described controller (2) is provided with controller connecting terminal (3), and is furnished with the remote controller matched with controller connecting terminal (3).
The pulse generating circuit, clock circuit and the drive circuit that are connected to each other is comprised in controller (2), power supply (1) is connected with pulse generating circuit, clock circuit and drive circuit respectively, clock circuit is connected with pulse generating circuit, pulse generating circuit is connected with drive circuit, and drive circuit is connected with LED matrix (6).
Described pulse generating circuit, clock circuit and drive circuit can be all form corresponding circuit by discrete component.Described power supply (1) is that power supply adaptor is connected with controller (2) by electric lead.
Described pulse generating circuit, produce the pulse frequency of 20 KHz per second, dutycycle is adjusted to 15%.Described clock circuit provides time standard and whole equipment starts, the time controling of stopping.
Described LED matrix is made up of the infrarede emitting diode of flexible printed circuit board and two groups of 660nm and 730nm wavelength, the infrarede emitting diode intersection of described two groups of different wave lengths is connected into a near infrared light flexible light stripe, is arranged on flexible printed circuit board with another near infrared light flexible light stripe parallel connected array.
Described LED matrix average light illumination is 5-25mW/cm2.During use, LED matrix can be close to ceruical uertebra part skin surface with the dynamics of 5-10g/cm2 by described flexible carrier.
Described LED matrix flexible carrier is made up of natural, artificial fabric and charges.
Experimenter B, suffers from serious Inheritance allergic rhinitis, and after using LED physiotherapy table course for the treatment of (seven days), total white blood cells is by 1.9 × 10
9/ L brings up to 2.9 × 10
9/ L, after two courses for the treatment of, total white blood cells is 3.7 × 10
9/ L, effectively slow rhinocnesmus, sneeze and watery nasal discharge symptom.
Claims (10)
1. the LED physiotherapy table for allergic rhinitis treatment, it is characterized in that: comprise power supply (1), controller (2), the flexible carrier (4) of LED matrix (6) and replaceable LED matrix, described power supply (1), controller (2), LED matrix (6) is installed on the flexible carrier (4) of replaceable LED matrix, LED matrix (6) is arranged on flexible carrier (4) inner side of replaceable LED matrix just to cervical vertebra place, power supply (1) and controller (2) are arranged on flexible carrier (4) outside of replaceable LED matrix back to cervical vertebra place, power supply (1), controller (2), LED matrix (6) is connected successively by conductor wire.
2. a kind of LED physiotherapy table for allergic rhinitis treatment according to claim 1, is characterized in that: flexible carrier (4) two ends of described replaceable LED matrix are provided with magic hasps (5); Described controller (2) is provided with controller connecting terminal (3), and is furnished with the remote controller matched with controller connecting terminal (3).
3. a kind of LED physiotherapy table for allergic rhinitis treatment according to claim 1, it is characterized in that: in controller (2), comprise the pulse generating circuit, clock circuit and the drive circuit that are connected to each other, power supply (1) is connected with pulse generating circuit, clock circuit and drive circuit respectively, clock circuit is connected with pulse generating circuit, pulse generating circuit is connected with drive circuit, and drive circuit is connected with LED matrix (6).
4. a kind of LED physiotherapy table for allergic rhinitis treatment according to claim 3, it is characterized in that: described pulse generating circuit, clock circuit and drive circuit both can be made up of integrated circuit and discrete component, also all can form corresponding circuit by discrete component; Described power supply both can be accumulator, also can be that power supply adaptor is connected with controller by electric lead.
5. a kind of LED physiotherapy table for allergic rhinitis treatment according to claim 3, it is characterized in that: described pulse generating circuit, produce the pulse frequency of 0.2-20 KHz per second, dutycycle is at 15-95% continuously adjustabe.
6. a kind of LED physiotherapy table for allergic rhinitis treatment according to claim 3, is characterized in that: described clock circuit provides time standard and whole equipment starts, the time controling of stopping.
7. a kind of LED physiotherapy table for allergic rhinitis treatment according to claim 1, it is characterized in that: described LED matrix (6) is made up of the infrarede emitting diode of flexible printed circuit board and two groups of different wave lengths, the infrarede emitting diode intersection of described two groups of different wave lengths is connected into a near infrared light flexible light stripe, is arranged on flexible printed circuit board with another near infrared light flexible light stripe parallel connected array; The wavelength of described infrarede emitting diode is from 630nm-780 nm; Described LED matrix (6) average light illumination is 5-25mW/cm2.
8. a kind of LED physiotherapy table for allergic rhinitis treatment according to claim 7, it is characterized in that: described LED matrix (6) is made up of the near-infrared luminous diode of two groups of different wave lengths, is the LED of 630nm and 660nm or 660nm and 730nm.
9. a kind of LED physiotherapy table for allergic rhinitis treatment according to claim 1, is characterized in that: described LED matrix flexible carrier (4) is made up of natural, artificial fabric and charges.
10., for a LED physiotherapy table for allergic rhinitis treatment, it is characterized in that: treat for allergic rhinitis; During use, LED matrix (6) can be close to ceruical uertebra part skin surface with the dynamics of 5-10g/cm2 by described flexible carrier.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510072352.2A CN104689484A (en) | 2015-02-12 | 2015-02-12 | LED physiotherapy instrument for treating allergic rhinitis and application method thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510072352.2A CN104689484A (en) | 2015-02-12 | 2015-02-12 | LED physiotherapy instrument for treating allergic rhinitis and application method thereof |
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| CN104689484A true CN104689484A (en) | 2015-06-10 |
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| CN201510072352.2A Pending CN104689484A (en) | 2015-02-12 | 2015-02-12 | LED physiotherapy instrument for treating allergic rhinitis and application method thereof |
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Cited By (2)
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| CN108543225A (en) * | 2018-04-03 | 2018-09-18 | 江西汉江科技发展有限公司 | A kind of near-infrared LED modality and its application improving HIV patient CD4+T lymphocytes and reduce that disease carries |
| CN114082108A (en) * | 2021-11-23 | 2022-02-25 | 固安翌光科技有限公司 | Sleep phototherapy device and control system for realizing adjuvant therapy |
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