CN104689369A - 一种人体可降解的耐蚀高强韧Zn‐Fe系锌合金及其应用 - Google Patents
一种人体可降解的耐蚀高强韧Zn‐Fe系锌合金及其应用 Download PDFInfo
- Publication number
- CN104689369A CN104689369A CN201510112259.XA CN201510112259A CN104689369A CN 104689369 A CN104689369 A CN 104689369A CN 201510112259 A CN201510112259 A CN 201510112259A CN 104689369 A CN104689369 A CN 104689369A
- Authority
- CN
- China
- Prior art keywords
- kirsite
- human body
- degradable
- strength
- corrosion
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000007797 corrosion Effects 0.000 title abstract description 13
- 238000005260 corrosion Methods 0.000 title abstract description 13
- 229910001297 Zn alloy Inorganic materials 0.000 title abstract description 8
- 239000000463 material Substances 0.000 claims abstract description 18
- 229910052725 zinc Inorganic materials 0.000 claims abstract description 18
- 229910052742 iron Inorganic materials 0.000 claims abstract description 14
- 239000007943 implant Substances 0.000 claims abstract description 7
- 238000002513 implantation Methods 0.000 claims description 10
- 239000011573 trace mineral Substances 0.000 claims description 9
- 235000013619 trace mineral Nutrition 0.000 claims description 9
- 210000000988 bone and bone Anatomy 0.000 claims description 8
- 229910052749 magnesium Inorganic materials 0.000 claims description 7
- 241000446313 Lamella Species 0.000 claims description 4
- 230000003872 anastomosis Effects 0.000 claims description 4
- 210000004204 blood vessel Anatomy 0.000 claims description 3
- 229910052791 calcium Inorganic materials 0.000 claims description 3
- 210000003445 biliary tract Anatomy 0.000 claims description 2
- 230000000968 intestinal effect Effects 0.000 claims description 2
- 229910052748 manganese Inorganic materials 0.000 claims description 2
- 230000001537 neural effect Effects 0.000 claims description 2
- 229910052761 rare earth metal Inorganic materials 0.000 claims description 2
- 229910052712 strontium Inorganic materials 0.000 claims description 2
- 210000003437 trachea Anatomy 0.000 claims description 2
- 210000003708 urethra Anatomy 0.000 claims description 2
- 239000011701 zinc Substances 0.000 abstract description 29
- 239000000956 alloy Substances 0.000 abstract description 17
- 238000006731 degradation reaction Methods 0.000 abstract description 17
- 230000015556 catabolic process Effects 0.000 abstract description 16
- 229910000861 Mg alloy Inorganic materials 0.000 abstract description 2
- 239000007857 degradation product Substances 0.000 abstract description 2
- 239000004615 ingredient Substances 0.000 abstract description 2
- 230000004060 metabolic process Effects 0.000 abstract description 2
- 230000007547 defect Effects 0.000 abstract 1
- XEEYBQQBJWHFJM-UHFFFAOYSA-N iron Substances [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 45
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 15
- 239000000203 mixture Substances 0.000 description 10
- PTFCDOFLOPIGGS-UHFFFAOYSA-N Zinc dication Chemical compound [Zn+2] PTFCDOFLOPIGGS-UHFFFAOYSA-N 0.000 description 8
- 238000012360 testing method Methods 0.000 description 8
- 229910045601 alloy Inorganic materials 0.000 description 7
- 239000011777 magnesium Substances 0.000 description 6
- 230000000694 effects Effects 0.000 description 5
- 238000011160 research Methods 0.000 description 5
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 4
- 229910000521 B alloy Inorganic materials 0.000 description 3
- 208000007536 Thrombosis Diseases 0.000 description 3
- 210000004027 cell Anatomy 0.000 description 3
- 238000007796 conventional method Methods 0.000 description 3
- 230000003203 everyday effect Effects 0.000 description 3
- 229910052751 metal Inorganic materials 0.000 description 3
- 239000002184 metal Substances 0.000 description 3
- 239000012890 simulated body fluid Substances 0.000 description 3
- 102000008186 Collagen Human genes 0.000 description 2
- 108010035532 Collagen Proteins 0.000 description 2
- CWYNVVGOOAEACU-UHFFFAOYSA-N Fe2+ Chemical compound [Fe+2] CWYNVVGOOAEACU-UHFFFAOYSA-N 0.000 description 2
- 239000011575 calcium Substances 0.000 description 2
- 229920001436 collagen Polymers 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 239000013078 crystal Substances 0.000 description 2
- 231100000263 cytotoxicity test Toxicity 0.000 description 2
- 230000012010 growth Effects 0.000 description 2
- 239000011159 matrix material Substances 0.000 description 2
- 239000012567 medical material Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 238000013508 migration Methods 0.000 description 2
- 230000005012 migration Effects 0.000 description 2
- 239000002861 polymer material Substances 0.000 description 2
- 230000008929 regeneration Effects 0.000 description 2
- 238000011069 regeneration method Methods 0.000 description 2
- 231100000331 toxic Toxicity 0.000 description 2
- 230000002588 toxic effect Effects 0.000 description 2
- 102000052866 Amino Acyl-tRNA Synthetases Human genes 0.000 description 1
- 108700028939 Amino Acyl-tRNA Synthetases Proteins 0.000 description 1
- 102000055007 Cartilage Oligomeric Matrix Human genes 0.000 description 1
- 101710176668 Cartilage oligomeric matrix protein Proteins 0.000 description 1
- 229910052684 Cerium Inorganic materials 0.000 description 1
- 206010061223 Ligament injury Diseases 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 238000005275 alloying Methods 0.000 description 1
- 210000000709 aorta Anatomy 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000003519 biomedical and dental material Substances 0.000 description 1
- 230000008468 bone growth Effects 0.000 description 1
- 159000000007 calcium salts Chemical class 0.000 description 1
- 210000000845 cartilage Anatomy 0.000 description 1
- 230000003197 catalytic effect Effects 0.000 description 1
- 230000001276 controlling effect Effects 0.000 description 1
- 229910052802 copper Inorganic materials 0.000 description 1
- 239000010949 copper Substances 0.000 description 1
- 231100000135 cytotoxicity Toxicity 0.000 description 1
- 230000003013 cytotoxicity Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000004069 differentiation Effects 0.000 description 1
- 230000009977 dual effect Effects 0.000 description 1
- 210000002950 fibroblast Anatomy 0.000 description 1
- 239000012634 fragment Substances 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 229910000765 intermetallic Inorganic materials 0.000 description 1
- JEIPFZHSYJVQDO-UHFFFAOYSA-N iron(III) oxide Inorganic materials O=[Fe]O[Fe]=O JEIPFZHSYJVQDO-UHFFFAOYSA-N 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 230000002503 metabolic effect Effects 0.000 description 1
- 239000007769 metal material Substances 0.000 description 1
- 230000017074 necrotic cell death Effects 0.000 description 1
- 238000011587 new zealand white rabbit Methods 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 230000011164 ossification Effects 0.000 description 1
- 210000000963 osteoblast Anatomy 0.000 description 1
- 210000002997 osteoclast Anatomy 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 238000012827 research and development Methods 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L17/00—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/04—Metals or alloys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/02—Inorganic materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
-
- C—CHEMISTRY; METALLURGY
- C22—METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
- C22C—ALLOYS
- C22C18/00—Alloys based on zinc
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Vascular Medicine (AREA)
- Surgery (AREA)
- Dermatology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Heart & Thoracic Surgery (AREA)
- Inorganic Chemistry (AREA)
- Mechanical Engineering (AREA)
- Metallurgy (AREA)
- Organic Chemistry (AREA)
- Materials For Medical Uses (AREA)
- Prostheses (AREA)
Abstract
Description
Claims (6)
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201510112259.XA CN104689369B (zh) | 2015-03-13 | 2015-03-13 | 一种人体可降解的耐蚀高强韧Zn‐Fe 系锌合金及其应用 |
PCT/CN2016/073438 WO2016145957A1 (zh) | 2015-03-13 | 2016-02-04 | 一种人体可降解的耐蚀高强韧Zn‐Fe 系锌合金及其应用 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201510112259.XA CN104689369B (zh) | 2015-03-13 | 2015-03-13 | 一种人体可降解的耐蚀高强韧Zn‐Fe 系锌合金及其应用 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN104689369A true CN104689369A (zh) | 2015-06-10 |
CN104689369B CN104689369B (zh) | 2017-06-30 |
Family
ID=53337180
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201510112259.XA Active CN104689369B (zh) | 2015-03-13 | 2015-03-13 | 一种人体可降解的耐蚀高强韧Zn‐Fe 系锌合金及其应用 |
Country Status (2)
Country | Link |
---|---|
CN (1) | CN104689369B (zh) |
WO (1) | WO2016145957A1 (zh) |
Cited By (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2016145957A1 (zh) * | 2015-03-13 | 2016-09-22 | 西安爱德万思医疗科技有限公司 | 一种人体可降解的耐蚀高强韧Zn‐Fe 系锌合金及其应用 |
CN106474545A (zh) * | 2015-08-28 | 2017-03-08 | 先健科技(深圳)有限公司 | 可吸收铁基合金植入医疗器械 |
CN106606800A (zh) * | 2015-10-21 | 2017-05-03 | 北京大学 | 一种Zn-Fe系锌合金及其制备方法与应用 |
CN106890356A (zh) * | 2016-03-10 | 2017-06-27 | 山东瑞安泰医疗技术有限公司 | 一种可降解的锌基合金植入材料及其制备方法与应用 |
CN106955374A (zh) * | 2016-01-08 | 2017-07-18 | 先健科技(深圳)有限公司 | 植入式器械 |
CN106974718A (zh) * | 2016-01-15 | 2017-07-25 | 西安爱德万思医疗科技有限公司 | 一种接骨螺钉 |
CN107460372A (zh) * | 2016-06-02 | 2017-12-12 | 北京大学 | 一种Zn‑Mn系锌合金及其制备方法与应用 |
CN110241453A (zh) * | 2019-04-25 | 2019-09-17 | 西南大学 | 一种缓释氟和铈的可降解锌合金骨钉及其制备方法 |
CN110512117A (zh) * | 2019-09-27 | 2019-11-29 | 石家庄新日锌业有限公司 | 一种医用锌合金材料及制备方法 |
CN113106295A (zh) * | 2021-03-16 | 2021-07-13 | 北京科技大学 | 一种可降解生物医用材料Zn-Si-X系锌合金及制备方法 |
CN115874104A (zh) * | 2022-11-25 | 2023-03-31 | 常州大学 | 一种医用可降解ZnFeMn中熵合金及其制备方法和应用 |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11351290B1 (en) | 2020-04-08 | 2022-06-07 | Admtech, Llc | Absorbable high-strength zinc alloy for medical implants |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1792381A (zh) * | 2005-12-22 | 2006-06-28 | 上海交通大学 | 生物体内可吸收的Mg-Zn-Ca-Fe多元镁合金材料 |
WO2009158333A2 (en) * | 2008-06-25 | 2009-12-30 | Boston Scientific Scimed, Inc. | Medical devices for delivery of therapeutic agent in conjunction with galvanic corrosion |
CN102605390A (zh) * | 2012-03-31 | 2012-07-25 | 大连理工大学 | 电铸制备血管支架用可降解Fe-Zn合金管材的方法 |
CN102634725A (zh) * | 2012-03-31 | 2012-08-15 | 大连理工大学 | 一种生物医用可腐蚀降解的二元Fe-Zn合金材料 |
CN103736152A (zh) * | 2013-12-26 | 2014-04-23 | 西安爱德万思医疗科技有限公司 | 一种人体可吸收的耐蚀高强韧锌合金植入材料 |
CN104195369A (zh) * | 2014-08-21 | 2014-12-10 | 北京大学 | 一种Zn-Ca系锌合金及其制备方法与应用 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1172011C (zh) * | 2001-09-17 | 2004-10-20 | 中国人民解放军海军工程大学 | 耐海水腐蚀用于热喷涂的锌合金及工艺 |
WO2008098924A2 (en) * | 2007-02-13 | 2008-08-21 | Cinvention Ag | Medical devices with extended or multiple reservoirs |
CN104689369B (zh) * | 2015-03-13 | 2017-06-30 | 西安爱德万思医疗科技有限公司 | 一种人体可降解的耐蚀高强韧Zn‐Fe 系锌合金及其应用 |
-
2015
- 2015-03-13 CN CN201510112259.XA patent/CN104689369B/zh active Active
-
2016
- 2016-02-04 WO PCT/CN2016/073438 patent/WO2016145957A1/zh active Application Filing
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1792381A (zh) * | 2005-12-22 | 2006-06-28 | 上海交通大学 | 生物体内可吸收的Mg-Zn-Ca-Fe多元镁合金材料 |
WO2009158333A2 (en) * | 2008-06-25 | 2009-12-30 | Boston Scientific Scimed, Inc. | Medical devices for delivery of therapeutic agent in conjunction with galvanic corrosion |
CN102605390A (zh) * | 2012-03-31 | 2012-07-25 | 大连理工大学 | 电铸制备血管支架用可降解Fe-Zn合金管材的方法 |
CN102634725A (zh) * | 2012-03-31 | 2012-08-15 | 大连理工大学 | 一种生物医用可腐蚀降解的二元Fe-Zn合金材料 |
CN103736152A (zh) * | 2013-12-26 | 2014-04-23 | 西安爱德万思医疗科技有限公司 | 一种人体可吸收的耐蚀高强韧锌合金植入材料 |
CN104195369A (zh) * | 2014-08-21 | 2014-12-10 | 北京大学 | 一种Zn-Ca系锌合金及其制备方法与应用 |
Non-Patent Citations (2)
Title |
---|
D. VOJTEˇCH等: ""Mechanical and corrosion properties of newly developed biodegradable Zn-based alloys for bone fixation"", 《ACTA BIOMATERIALIA》 * |
王伟强等: ""Fe-Zn合金的粉末冶金法制备及其生物降解特性研究"", 《功能材料》 * |
Cited By (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2016145957A1 (zh) * | 2015-03-13 | 2016-09-22 | 西安爱德万思医疗科技有限公司 | 一种人体可降解的耐蚀高强韧Zn‐Fe 系锌合金及其应用 |
CN106474545A (zh) * | 2015-08-28 | 2017-03-08 | 先健科技(深圳)有限公司 | 可吸收铁基合金植入医疗器械 |
US10946121B2 (en) | 2015-08-28 | 2021-03-16 | Biotyx Medical (Shenzhen) Co., Ltd. | Absorbable iron-based alloy implantable medical device |
CN106606800A (zh) * | 2015-10-21 | 2017-05-03 | 北京大学 | 一种Zn-Fe系锌合金及其制备方法与应用 |
CN106606800B (zh) * | 2015-10-21 | 2019-05-14 | 北京大学 | 一种Zn-Fe系锌合金及其制备方法与应用 |
CN106955374A (zh) * | 2016-01-08 | 2017-07-18 | 先健科技(深圳)有限公司 | 植入式器械 |
CN106974718A (zh) * | 2016-01-15 | 2017-07-25 | 西安爱德万思医疗科技有限公司 | 一种接骨螺钉 |
US20190083685A1 (en) * | 2016-03-10 | 2019-03-21 | Shandong Rientech Medical Tech Co., Ltd. | Degradable zinc base alloy implant material and preparation method and use thereof |
CN106890356A (zh) * | 2016-03-10 | 2017-06-27 | 山东瑞安泰医疗技术有限公司 | 一种可降解的锌基合金植入材料及其制备方法与应用 |
CN106955376A (zh) * | 2016-03-10 | 2017-07-18 | 山东瑞安泰医疗技术有限公司 | 一种可降解的锌基合金植入材料在制备骨科植入物中的应用 |
CN106913916A (zh) * | 2016-03-10 | 2017-07-04 | 山东瑞安泰医疗技术有限公司 | 一种可降解的锌基合金植入材料在制备血管支架中的应用 |
WO2017152878A1 (zh) * | 2016-03-10 | 2017-09-14 | 山东瑞安泰医疗技术有限公司 | 一种可降解的锌基合金植入材料及其制备方法与应用 |
CN106890356B (zh) * | 2016-03-10 | 2020-07-24 | 山东瑞安泰医疗技术有限公司 | 一种可降解的锌基合金植入材料及其制备方法与应用 |
CN107460372A (zh) * | 2016-06-02 | 2017-12-12 | 北京大学 | 一种Zn‑Mn系锌合金及其制备方法与应用 |
CN107460372B (zh) * | 2016-06-02 | 2019-06-25 | 北京大学 | 一种Zn-Mn系锌合金及其制备方法与应用 |
CN110241453A (zh) * | 2019-04-25 | 2019-09-17 | 西南大学 | 一种缓释氟和铈的可降解锌合金骨钉及其制备方法 |
CN110512117A (zh) * | 2019-09-27 | 2019-11-29 | 石家庄新日锌业有限公司 | 一种医用锌合金材料及制备方法 |
CN110512117B (zh) * | 2019-09-27 | 2022-05-13 | 石家庄新日锌业有限公司 | 一种医用锌合金材料及制备方法 |
CN113106295A (zh) * | 2021-03-16 | 2021-07-13 | 北京科技大学 | 一种可降解生物医用材料Zn-Si-X系锌合金及制备方法 |
CN115874104A (zh) * | 2022-11-25 | 2023-03-31 | 常州大学 | 一种医用可降解ZnFeMn中熵合金及其制备方法和应用 |
CN115874104B (zh) * | 2022-11-25 | 2024-05-03 | 常州大学 | 一种医用可降解ZnFeMn中熵合金及其制备方法和应用 |
Also Published As
Publication number | Publication date |
---|---|
WO2016145957A1 (zh) | 2016-09-22 |
CN104689369B (zh) | 2017-06-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN104689369A (zh) | 一种人体可降解的耐蚀高强韧Zn‐Fe系锌合金及其应用 | |
CN104689378B (zh) | 一种人体可降解的耐蚀高强韧Zn‐Fe‐X系锌合金及其应用 | |
CN104651664B (zh) | 一种人体可降解的耐蚀高强韧Zn‐Fe‐RE系锌合金及其应用 | |
CN104651665B (zh) | 一种人体可降解的耐蚀高强韧Zn‐Fe‐Li 系锌合金及其应用 | |
CN109680195B (zh) | 一种Mg-RE系镁合金及其制备方法与应用 | |
Wang et al. | Research progress of biodegradable magnesium-based biomedical materials: A review | |
CN106319287A (zh) | 生物可降解医用Zn‑Li‑X系合金材料及制备与应用 | |
CN101837145B (zh) | 生物体内可降解高强韧耐蚀镁合金内植入材料 | |
CN108754232A (zh) | 一种高强高塑可生物降解Zn-Mn-Li系锌合金及其用途 | |
WO2017084363A1 (zh) | 医用可降解Zn-Cu-X合金材料及其制备方法 | |
CN108315583B (zh) | 一种Zn-Li-Mn系锌合金及其制备方法与应用 | |
CN111334688B (zh) | 一种Zn-RE系锌合金及其制备方法与应用 | |
CN108277386A (zh) | 一种Zn-Li-Mg系锌合金及其制备方法与应用 | |
US20190153570A1 (en) | Fully degradable magnesium alloy and preparation method thereof | |
CN108588484A (zh) | 一种高强高塑可生物降解Zn-Mn-Mg系锌合金及其制备方法 | |
CN1792383A (zh) | 生物体内可吸收的Mg-Zn-Ca三元镁合金材料 | |
WO2020042745A1 (zh) | 降解速率可控的Mg-Zn-Sn系镁合金及其制备方法和应用 | |
CN100372574C (zh) | 生物体内可吸收的Mg-Zn-Ca-Fe多元镁合金材料 | |
CN106282664A (zh) | 生物可降解医用锌锂二元合金材料及其制备方法与应用 | |
CN108165782B (zh) | 一种医用锌基合金带材及其制备方法 | |
Yan et al. | Comparison of the effects of Mg–6Zn and Ti–3Al–2.5 V alloys on TGF-β/TNF-α/VEGF/b-FGF in the healing of the intestinal tract in vivo | |
CN106606801A (zh) | 一种Zn-ZnO系锌合金及其制备方法与应用 | |
CN108728770B (zh) | 一种应用于医用植入支架的超高抗菌性能奥氏体不锈钢 | |
EP3395971B1 (en) | Alloy material and application thereof | |
CN106606806A (zh) | 一种Zn-Mg1Ca系锌合金及其制备方法与应用 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
TA01 | Transfer of patent application right | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20170601 Address after: Two Shaanxi city of Xi'an province high tech Zone Industrial Park Jin industry Xinkai building A layer Applicant after: XI'AN ADVANCED MEDICAL TECHNOLOGY Co.,Ltd. Address before: Delaware Applicant before: Zhou Gongyao |
|
GR01 | Patent grant | ||
GR01 | Patent grant | ||
EE01 | Entry into force of recordation of patent licensing contract |
Application publication date: 20150610 Assignee: Shaanxi Chunhui bioco medical technology LLC Assignor: XI'AN ADVANCED MEDICAL TECHNOLOGY Co.,Ltd. Contract record no.: 2017610000020 Denomination of invention: Degradable corrosion-resistant high-toughness Zn-Fe zinc alloy for human body and application thereof Granted publication date: 20170630 License type: Exclusive License Record date: 20170713 |
|
EE01 | Entry into force of recordation of patent licensing contract | ||
EC01 | Cancellation of recordation of patent licensing contract | ||
EC01 | Cancellation of recordation of patent licensing contract |
Assignee: Shaanxi Chunhui bioco medical technology LLC Assignor: XI'AN ADVANCED MEDICAL TECHNOLOGY Co.,Ltd. Contract record no.: 2017610000020 Date of cancellation: 20180426 |
|
TR01 | Transfer of patent right |
Effective date of registration: 20240712 Address after: Room 801, Building B, Hanguang Jiayuan Community, No. 67 Gaoxin Road, Xi'an City, Shaanxi Province, China 710073 Patentee after: Xue Yong Country or region after: China Address before: 710000 first floor, building a, Xinkai Industrial Park, Jinye Second Road, high tech Zone, Xi'an, Shaanxi Province Patentee before: XI'AN ADVANCED MEDICAL TECHNOLOGY Co.,Ltd. Country or region before: China |
|
TR01 | Transfer of patent right |
Effective date of registration: 20240717 Address after: No. 801, Building B, Hanguang Jiayuan, No. 67 Gaoxin Road, Xi'an City, Shaanxi Province, China 710073 Patentee after: Qu Gongqi Country or region after: China Address before: Room 801, Building B, Hanguang Jiayuan Community, No. 67 Gaoxin Road, Xi'an City, Shaanxi Province, China 710073 Patentee before: Xue Yong Country or region before: China |