CN104689093A - Medicine for treating proliferation of mammary gland - Google Patents
Medicine for treating proliferation of mammary gland Download PDFInfo
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- CN104689093A CN104689093A CN201510147236.2A CN201510147236A CN104689093A CN 104689093 A CN104689093 A CN 104689093A CN 201510147236 A CN201510147236 A CN 201510147236A CN 104689093 A CN104689093 A CN 104689093A
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Abstract
The invention relates to the technical field of medicines, in particular to a medicine for treating proliferation of the mammary gland. The medicine comprises, by weight, 50-95 parts of uniflower swisscentaury roots, 70-130 parts of cluster mallow fruits, 40-60 parts of chinese rose flowers, 65-90 parts of tribulus terrestris, 45-85 parts of polygala amflra, 50-100 parts of concha meretricis seu cyclinae, 30-60 parts of chlorite schist, 100-200 parts of indian rorippa herb, 60-90 parts of rhizoma cyperi, 30-50 parts of longstamen onion bulb, 40-80 parts of radix aristolochiae, 50-90 parts of campsis grandiflora, 10-50 parts of garden balsam, 40-80 parts of gastrodin, 70-120 parts of phillyrin, 70-120 parts of lilies, 60-120 parts of fructus lycii, 80-150 parts of lotus seeds, 20-60 parts of sanchi flowers, 150-250 parts of bananas and 150-250 parts of grapes. The medicine can cure the symptoms of proliferation of the mammary gland, also can prevent disease relapse fundamentally, is remarkable in treatment effect, and can be easily absorbed by a human body. Clinic tests show that the total effective rate of the medicine reaches 100%.
Description
Technical field
The present invention relates to technical field of pharmaceuticals, particularly a kind of medicine for the treatment of cyclomastopathy.
Background technology
Cyclomastopathy refers to breast epithelium and proliferation of fibrous tissue, mammary gland tissue conduit and newborn lobule degeneration structurally and the growth of Progressive symmetric erythrokeratodermia connective tissue, and its pathogenic factor is mainly due to endocrine hormone imbalance.Cyclomastopathy is the modal cystic hyperplasia of breast of women, and its sickness rate accounts for the first place of mastopathy.This sick sickness rate was in the trend risen year by year in the last few years, and the age also more and more becomes younger.About there is the women of 70-80% to have cyclomastopathy in various degree according to investigations, be more common in the women in 25-45 year.
At present, Domestic Medicine circle treatment cyclomastopathy method be roughly divided into two kinds: operative therapy and pharmacotherapy.Expenses of surgical treatment is too high, and relapse rate is high, because he can only removal lesion tissue, can not eradicate this cause of disease of endocrine disturbance, and operation not only can cause outside directly damage the health of patient, but also can give that women's cause lifelong wound at heart.
And Drug therapy is divided into Western medicine and treatment by Chinese herbs.Doctor trained in Western medicine thinks that darkness of mood, emotion is too exciting, cerebral cortex dysfunction, endocrine disturbance, the too high initiation breast lesion of estrogen due to work overstrain.Doctor trained in Western medicine mainly uses hormone therapy cyclomastopathy, but hormone therapy side effect is large, and long skin sore, mottle on the face appear in a lot of people after having used hormone therapy, body surface hirsutism, osteoporosis, cardiopalmus hyperhidrosis etc.
The Chinese medicine of Current therapeutic hyperplasia of mammary glands is of a great variety, and the Chinese invention patent being 201410548893.3 as application number discloses a kind of pharmaceutical composition for the treatment of cyclomastopathy, and its raw material comprises by weight: Herba Taraxaci 9 ~ 11 parts, Fructus Forsythiae 9 ~ 11 parts, Sargassum 7 ~ 9 parts, Thallus Laminariae (Thallus Eckloniae) 7 ~ 9 parts, Concha Ostreae 9 ~ 11 parts, Flos Chrysanthemi Indici 9 ~ 11 parts, the Cortex Eucommiae 9 ~ 11 parts, Rhizoma Corydalis 5 ~ 7 parts, Radix Bupleuri 5 ~ 7 parts, Radix Curcumae 5 ~ 7 parts, Placenta Hominis 1 ~ 3 part.And for example application number be 201410007274.3 Chinese invention patent disclose a kind of Chinese medicine preparation for the treatment of cyclomastopathy, composed of the following components: Radix Bupleuri 12g, Radix Paeoniae Alba 10g, Fructus Aurantii 12g, Radix Angelicae Sinensis 10g, Poria 10g, Rhizoma Atractylodis Macrocephalae 12g, Rhizoma Cyperi (processed with vinegar) 15g, Pericarpium Citri Reticulatae Viride 12g, Radix Salviae Miltiorrhizae 20g, Pheretima 15g, Bulbus Fritillariae Cirrhosae 12g, Concha Ostreae 30g, Endothelium Corneum Gigeriae Galli 15g, Fructus Toosendan 12g, Fructus Trichosanthis 20g, Radix Glycyrrhizae 6g.For another example application number be 201310558355.8 Chinese invention patent disclose a kind of Chinese medicine composition being used for the treatment of cyclomastopathy, it comprises part for oral administration: the medicament be made up of following bulk drugs: Bulbus Fritillariae Thunbergii, Semen Armeniacae Amarum, Ilex purpurea Hassk.[I.chinensis Sims, Rhizoma Imperatae, Herba Hedyotidis Diffusae, Radix Ophiopogonis, Semen Vaccariae, Rhizoma Cyperi, Fructus Piperis Longi, Radix Bupleuri, the fruit-rind of Chinese trichosanthes; External part is the medicament be made up of following bulk drugs: Radix Rhodiolae, Herba Erigerontis, Radix Tripterygii Wilfordii, the fruit-rind of Chinese trichosanthes, Radix Bupleuri, Retinervus Luffae Fructus, Herba Artemisiae Scopariae, Oleum sesami, Olibanum, Myrrha, Borneolum Syntheticum.Mostly above Chinese medicine is that index is not effected a permanent cure, and is heat-clearing and toxic substances removing substantially, dispersing swelling and dissipating binds, can also dispelling wind suppressing the hyperactive liver, subduing hyperactive YANG to ease mental disorders, and softening and eliminating sputum, restrains astringent or styptic treatment for spontaneous sweating, and these substantially can mitigate the disease, also easily recurs, can not remove the state of an illness from source even if cure.According to the etiology and pathogenesis of cyclomastopathy, want to prevent cyclomastopathy, being exactly want keeping tensions down melancholy, is that mood is in optimistic state.
Summary of the invention
Technical problem to be solved by this invention be to provide a kind of can from the medicine of basic treatment cyclomastopathy, this medicine is treated from source, and therapeutic effect is remarkable, does not recur.
For achieving the above object, the present invention adopts following technical scheme:
Treat a medicine for cyclomastopathy, be made up of the raw material of following weight portion:
Preferably, Fructus Musae of the present invention is dry banana chip.
Preferably, Fructus Vitis viniferae of the present invention is the dry Fructus Vitis viniferae of purple.
Research finds, the generation of various emotion has direct relation with the height of brain Cucumber concentration at that time.Happy emotion, often relevant with the material of 5-hydroxy tryptamine that cries a kind of in brain, and offending emotion, then increase relevant with IC norepinephrine.A lot of food all can have a certain impact to the generation of IC 5-hydroxy tryptamine and norepinephrine.Fructus Musae and purple Fructus Vitis viniferae contain a kind of material that brain can be helped to produce 5-hydroxy tryptamine, and this material can impel the mood of people to become happy and peaceful, even can ease the pain, and the hormone causing people unhappy can be made again to greatly reduce.Therefore, edible banana and purple Portugal can make brain produce enough 5-hydroxy tryptamine, thus alleviate its pessimistic degree constrained, and even make not good emotion Lock-out, can fundamentally treat and preventing mammary gland hyperplasia.
The medicine of described treatment cyclomastopathy, its preparation method is as follows:
The preparation method of the medicine for the treatment of cyclomastopathy of the present invention is as follows:
By whole raw material mix homogeneously, pulverize, the raw material of raw material gross mass 1/3 is put into raw material gross weight 8 ~ 14 times of water and boil, keep fluidized state 60 ~ 110min, filter, obtain filtrate, then the raw material adding raw material gross mass 1/3 again in filtrate boils, and keeps fluidized state 70 ~ 120min, filters, obtain second time filtrate, the last raw material adding remaining raw material gross mass 1/3 in second time filtrate boils, and keeps fluidized state 80 ~ 130min, filters, compression, makes required preparation.
Preferably, the medicine for the treatment of cyclomastopathy of the present invention, be made up of the raw material of following weight portion:
Radix Rhapontici is the dry root of feverfew centaurea monanthos Georgi Rhaponticum uniflorum (L.) DC..Nature and flavor: bitter, cold.Function cures mainly: heat-clearing and toxic substances removing, eliminating carbuncle, stimulating milk secretion, and relaxing muscles and tendons is promoted blood circulation.Swell and ache for acute mastitis, carbuncle carbuncle on the back, scrofula sore, galactostasis, arthralgia chiefly caused by damp pathogen contracture.
Semen Abutili is the seed of Malvaceae plant Semen Abutili.Nature and flavor: sweet, cold.Function cures mainly: diuretic, laxation, stimulating milk secretion.Control constipation and anuresis, gonorrhea, edema, women's galactozemia, breast swell and pain.
Flos Rosae Chinensis, be the dried floral of rosaceous plant Chinese rose Rosa chinensis Jacq., its root, leaf are also used as medicine.Nature and flavor: sweet, temperature.Function cures mainly: promoting blood flow to regulate menstruation, loose poison detumescence.Flower: for menoxenia, dysmenorrhea, carbuncle furuncle and phyma poison, tuberculous lymphadenitis (non-diabrosis).
Fructus Atriplicis Sibiricae is the dry mature fruit of zygophyllaceae plant Fructus Tribuli Tribulus terrestris L..Nature and flavor: pungent, bitter, tepor; Slightly poisonous.Function cures mainly: suppressing the hyperactive liver resolving depression, promoting blood circulation by removing wind, and improving eyesight is antipruritic.Dizzy for having a headache, distending pain in the chest and hypochondrium, breast closes acute mastitis, cataract, rubella pruritus.
Radix Polygalae is the dry root of milk wort Radix Polygalae Polygala tenuifolia Willd. or ovum leaf Radix Polygalae Polygalasibirica L..Nature and flavor: bitter, pungent, warm.Function cures mainly: Fructus Alpiniae Oxyphyllae of calming the nerves, and eliminates the phlegm, detumescence.For the insomnia and dreamful sleep that disarmony between the heart and kidney causes, forgetful palpitation with fear, staring spells, expectoration is not well, sore swollen toxin, breast swell and pain.
Concha Meretricis seu Cyclinae is the shell of several sea clams such as Veneridae animal Concha Meretricis Seu Cyclinae.Nature and flavor: salty are flat.Function cures mainly: heat clearing away, and diuretic reduces phlegm, softening the hard mass.Control heat-phlegm to breathe heavily and cough, edema, gonorrhea, wart, tumor, gather, blood agglomeration chest pain, dysentery, hemorrhoid, metrorrhagia, leukorrhagia.
Lapis Micae Aureus is stone or the particle of metamorphic rock rocks chlorite schist or mica schist.Nature and flavor: salty are flat.Function cures mainly: the pendant expectorant therapeutic method to keep the adverse QI flowing downwards, checking hyperfunction of the liver for relieving convulsion.For pertinacious phlegm, old expectorant is cementing, the excess syndrome of QI rising in reverse order cough with asthma; That contains in phlegm-fire is demented, infantile convulsion; Clearing away phlegm helps digestion, and softening the hard mass disappears painful abdominal mass.
Herba Rorippae, Shi word Hua Ke Herba Rorippae Shu Zhi Wu Herba Rorippae Rorippa montana (Wall.) Small or Herba Rorippae Rorippa indica (L.) Hiern., with all herbal medicine.Nature and flavor: sweet, light, cool.Function cures mainly: removing heat from the lung and dissipating phlegm, heat-clearing and toxic substances removing, promoting blood circulation to restore menstrual flow, dampness removing jaundice eliminating.Breathe heavily for expectorant heat syndrome cough; Blood stasis amenorrhea, traumatic injury, arthromyodynia; Pyretic toxicity carbuncle sore, chilly skin ulcer, laryngopharynx swelling and pain, Serpentis hinders; Jaundice due to damp-heat; Invigorating the stomach and promoting digestion, inducing diuresis to remove edema.
Rhizoma Cyperi is the dry rhizome of sedge dried tuber Cyperus rotundus L..Nature and flavor: pungent, micro-hardship, micro-sweet are flat.Function cures mainly: promoting QI circulation for relieving depression, menstruction regulating and pain relieving.For stagnation of QI due to depression of the liver, breast, the side of body, abdominal distention, dyspepsia, breast gastral cavity painful abdominal mass is vexed, and colic of cold type is suffered from abdominal pain, distending pain of the breast, menoxenia, amenorrhea dysmenorrhea.
Bulbus Allii Macrostemonis is the dry bulb of liliaceous plant Allium macrostemon Allium macrostemon Bge..Nature and flavor: pungent, bitter, temperature.Function cures mainly: activating YANG and eliminating stagnation, circulation of qi promoting intestinal stasis relieving.For thoracic obstruction pain, phlegm retention cough with asthma is heavy after letting out dysentery.
Radix Aristolochiae is the dry root of aristolochiaceae plant Fructus Aristolochiae Aristolochia debilis Sieb.et Zucc..Nature and flavor: pungent, bitter, cold.Function cures mainly: suppressing the hyperactive liver pain relieving, removing toxic substances and promoting subsidence of swelling.For dizziness and headache, chest and abdomen swelling and pain, carbuncle furuncle, snake bite and insect sting.
Flos Campsis, for reaching the clouds the dried floral of Campsis radicans (L.) Seem. in reach the clouds Campsis grandiflora (Thunb.) K.Schum. or America of bavin Wei section plant.Nature and flavor: pungent, are slightly cold.Function cures mainly: removing blood stasis stimulates the menstrual flow, and removing heat from blood is dispelled.For blood stasis amenorrhea, menoxenia , lumps in the chest and abdomen; Wind heat prurigo.
Flos Impatientis is the flower of Balsaminaceae plant Flos Impatientis Impatiens balsamina L..Nature and flavor: sweet, temperature.Function cures mainly: promoting blood circulation and detumescence pain relieving, dispels the wind.For blood stasis amenorrhea, dysmenorrhea, prolonged lochia, traumatic injury; Rheumatic arthralgia, limbs are attached undue importance to one thing to the neglect of the other, and are unable to leave the bed; Carbuncle poison furuncle, starves palm wind, tinea unguium.
Rhizoma Gastrodiae is the dry tuber of orchid Rhizoma Gastrodiae Gastrodia elata Blume..Nature and flavor: sweet are flat.Function cures mainly: endogenous wind stopping relieving convulsion, suppressing liver-YANG, dispelling wind and removing obstruction in the collateral.For liver-wind stirring up internally, infantile convulsion is twitched; For excessive rising of liver-YANG, have a headache dizzy; Twitch for limb fiber crops spasm, rheumatoid arthritis stubborn.
Fructus Forsythiae is the dry fruit of Oleaceae plants Fructus Forsythiae Forsythia suspensa (Thunb.) Vahl.Nature and flavor: bitter, are slightly cold.Function cures mainly: heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.For carbuncle, scrofula, acute mastitis, erysipelas, anemopyretic cold, epidemic febrile disease from the beginning of, warmly join the army, high hot excessive thirst, coma sends out speckle, pyretic stranguria urine retention.
Bulbus Lilii is the dry meat scale leaf of liliaceous plant tiger lily Lilium lancifolium Thunb., Bulbus Lilii Liliumbrownii F.E.Brown var.viridulum Baker or Lilium tenuifolium Lilium pumilum DC..Nature and flavor: sweet, cold.Function cures mainly: nourishing YIN and moistening the lung, clearing away heart-fire for tranquillization.For deficiency of YIN chronic cough, sputum mixed with blood, fidgets due to deficiency is palpitated with fear, insomnia and dreamful sleep, absentminded.
Fructus Lycii is the dry mature fruit of plant of Solanaceae lycium barbarum Lycium barbarum L..Summer, autumn two gather when season, fruit took on a red color, hot-air seasoning, removing carpopodium.Nature and flavor: sweet are flat.Function cures mainly: nourishing the liver and kidney, replenishing vital essence to improve eyesight.For asthenia damage of essence, soreness of waist and knee joint, vertigo and tinnitus, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, and blurred vision is failed to understand.
Semen Nelumbinis are the dry mature seed of nymphaeaceae plant lotus Nelumbo nucifera Gaertn..Nature and flavor: sweet, puckery are flat.Function cures mainly: spleen reinforcing antidiarrheal, kidney tonifying arresting seminal emission, tranquilizing by nourishing the heart.For insufficiency of the spleen chronic diarrhea, seminal emission leukorrhagia, palpitation and insomnia.
Flower of Radix Notoginseng is the dry product of araliaceae ginseng plant Radix Notoginseng (Panax pseudoginsengWall.var.notoginseng (Burkill) Hoo et T seng) inflorescence.Nature and flavor: sweet and slightly bitter taste.Function cures mainly: the effect with heat clearing away, suppressing the hyperactive liver, blood pressure lowering, is applicable to giddy, dizzy, tinnitus, the disease such as hypertension and acute pharyngolaryngitis.
Fructus Musae is the fruit of Musaceae plant banana.Nature and flavor: sweet, cold.Function cures mainly: heat clearing away, intestine moistening, removing toxic substances.Control calentura excessive thirst, constipation, hemorrhoidal bleeding.
Fructus Vitis viniferae is the fruit of vitaceae Fructus Vitis viniferae.Nature and flavor: sweet acid are flat.Function cures mainly: fill blood, bone and muscle strengthening, diuresis.Control deficient qi and blood, cough due to deficiency of the lung, palpitation and night sweat, Bi condition, gonorrhea, edema.
The present invention is directed to the etiology and pathogenesis of cyclomastopathy, select plurality of raw materials reasonable combination, Radix Rhapontici, Flos Campsis, Herba Rorippae is active stimulates the menstrual flow, circulation of qi promoting intestinal stasis relieving; Semen Abutili, Flos Rosae Chinensis, Concha Meretricis seu Cyclinae, Lapis Micae Aureus, Radix Aristolochiae, Flos Impatientis, Fructus Forsythiae reducing swelling and alleviating pain, hard masses softening and resolving; Fructus Atriplicis Sibiricae, Rhizoma Cyperi, Bulbus Allii Macrostemonis, Rhizoma Gastrodiae, flower of Radix Notoginseng, promoting QI circulation for relieving depression, checking hyperfunction of the liver for relieving convulsion; Bulbus Lilii, Fructus Lycii, Semen Nelumbinis nourishing the liver and kidney, clearing away heart-fire for tranquillization; Fructus Musae and the helpful brain of Fructus Vitis viniferae produce the material of 5-hydroxy tryptamine, make the happy peacefulness of people's mood, ease the pain, greatly reduce unhappy hormone.By the medicine that preparation method of the present invention prepares, in batches decoction filtering, can abundant refinement material composition, be easy to absorption of human body.Medicine of the present invention can cure the symptom that cyclomastopathy occurs, also fundamentally can prevent disease relapse, therapeutic effect is remarkable.Confirm through clinical trial, total effective rate of the present invention reaches 100%
Detailed description of the invention
Below in conjunction with embodiment, the invention will be further described, but the present invention is not limited to these embodiments.
Embodiment 1
Treat a medicine for cyclomastopathy, be made up of the raw material of following weight portion:
The medicine of described treatment cyclomastopathy, its preparation method is as follows:
By whole raw material mix homogeneously, pulverize, the raw material of raw material gross mass 1/3 is put into raw material gross weight 8 times of water and boil, keep fluidized state 60min, filter, obtain filtrate, then the raw material adding raw material gross mass 1/3 again in filtrate boils, and keeps fluidized state 70min, filters, obtain second time filtrate, the raw material finally adding remaining raw material gross mass 1/3 in second time filtrate boils, and keeps fluidized state 80min, filter, compression, general ball, makes pill.
Embodiment 2
Treat a medicine for cyclomastopathy, be made up of the raw material of following weight portion:
The medicine of described treatment cyclomastopathy, its preparation method is as follows:
By whole raw material mix homogeneously, pulverize, the raw material of raw material gross mass 1/3 is put into raw material gross weight 10 times of water and boil, keep fluidized state 75min, filter, obtain filtrate, then the raw material adding raw material gross mass 1/3 again in filtrate boils, and keeps fluidized state 80min, filters, obtain second time filtrate, the raw material finally adding remaining raw material gross mass 1/3 in second time filtrate boils, and keeps fluidized state 90min, filter, compression, tabletting, makes tablet.
Embodiment 3
Treat a medicine for cyclomastopathy, be made up of the raw material of following weight portion:
The medicine of described treatment cyclomastopathy, its preparation method is as follows:
By whole raw material mix homogeneously, pulverize, the raw material of raw material gross mass 1/3 is put into raw material gross weight 11 times of water and boil, keep fluidized state 95min, filter, obtain filtrate, then the raw material adding raw material gross mass 1/3 again in filtrate boils, and keeps fluidized state 95min, filters, obtain second time filtrate, the raw material finally adding remaining raw material gross mass 1/3 in second time filtrate boils, and keeps fluidized state 105min, filter, compression, general ball, makes pill.
Embodiment 4
Treat a medicine for cyclomastopathy, be made up of the raw material of following weight portion:
The medicine of described treatment cyclomastopathy, its preparation method is as follows:
By whole raw material mix homogeneously, pulverize, the raw material of raw material gross mass 1/3 is put into raw material gross weight 13 times of water and boil, keep fluidized state 105min, filter, obtain filtrate, then the raw material adding raw material gross mass 1/3 again in filtrate boils, and keeps fluidized state 110min, filters, obtain second time filtrate, the raw material finally adding remaining raw material gross mass 1/3 in second time filtrate boils, and keeps fluidized state 115min, filter, compression, tabletting, makes tablet.
Embodiment 5
Treat a medicine for cyclomastopathy, be made up of the raw material of following weight portion:
The medicine of described treatment cyclomastopathy, its preparation method is as follows:
By whole raw material mix homogeneously, pulverize, the raw material of raw material gross mass 1/3 is put into raw material gross weight 14 times of water and boil, keep fluidized state 110min, filter, obtain filtrate, then the raw material adding raw material gross mass 1/3 again in filtrate boils, and keeps fluidized state 120min, filters, obtain second time filtrate, the raw material finally adding remaining raw material gross mass 1/3 in second time filtrate boils, and keeps fluidized state 130min, filter, compression, general ball, makes pill.
Claims (2)
1. treat a medicine for cyclomastopathy, it is characterized in that, be made up of the raw material of following weight portion:
Described Fructus Musae is dry banana chip;
Described Fructus Vitis viniferae is the dry Fructus Vitis viniferae of purple;
The medicine of described treatment cyclomastopathy, its preparation method is as follows:
By whole raw material mix homogeneously, pulverize, the raw material of raw material gross mass 1/3 is put into raw material gross weight 8 ~ 14 times of water and boil, keep fluidized state 60 ~ 110min, filter, obtain filtrate, then the raw material adding raw material gross mass 1/3 again in filtrate boils, and keeps fluidized state 70 ~ 120min, filters, obtain second time filtrate, the last raw material adding remaining raw material gross mass 1/3 in second time filtrate boils, and keeps fluidized state 80 ~ 130min, filters, compression, makes required preparation.
2. the medicine for the treatment of cyclomastopathy according to claim 1, is characterized in that, is made up of the raw material of following weight portion:
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Cited By (1)
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CN115040602A (en) * | 2022-06-23 | 2022-09-13 | 广东罗浮山国药股份有限公司 | Pharmaceutical composition for improving hyperplasia of mammary glands and preparation method thereof |
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2015
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Publication number | Priority date | Publication date | Assignee | Title |
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CN115040602A (en) * | 2022-06-23 | 2022-09-13 | 广东罗浮山国药股份有限公司 | Pharmaceutical composition for improving hyperplasia of mammary glands and preparation method thereof |
CN115040602B (en) * | 2022-06-23 | 2023-04-07 | 广东罗浮山国药股份有限公司 | Pharmaceutical composition for improving hyperplasia of mammary glands and preparation method thereof |
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