CN104688927A - Paste formula for invigorating kidney and nourishing essence - Google Patents
Paste formula for invigorating kidney and nourishing essence Download PDFInfo
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Abstract
The invention discloses a paste formula for invigorating kidney and nourishing essence, and relates to the field of treatment infertility caused by varicocele in traditional Chinese medicine. The paste formula is composed of the following traditional Chinese medicine raw materials in weight ratio: 10-20g of herba epimedii, 10-20g of prepared rehmannia root, 5-15g of salted morinda officinalis, 12-18g of fructus lycii, 10-20g of semen cuscutae, 8-15g of semen plantaginis, 5-16g of schisandra chinensis, 10-20g of raspberry, 5-15g of cistanche, 5-12g of flatstem milkvetch seed, 10-20g of prepared fleece flower root, 10-15g of deer-horn glue, 25-35g of cynanchum paniculatum and 5-12g of licorice. The traditional Chinese medicine paste formula for invigorating kidney and nourishing essence disclosed by the invention has an obvious effect of perfecting seminal fluid quality after varicocele operation, can greatly increase the sperm concentration, improve the sperm vitality and improve the pregnancy rate of patients. The paste is convenient to carry and store and is conveniently taken by patients to ensure the curative effect.
Description
Technical field
The present invention relates to Chinese traditional treatment varicocele and cause infertility field, specifically a kind of the kidney invigorating and essence nourishing cream side.
Background technology
Along with the reason such as environmental pollution and social factor, the sickness rate of infertility has the trend day by day increased at present, and the couple at child-bearing age in the whole world about 10 ~ 15% has growing barrier.Since finding from microscope, the sperm concentration of male reduces half, and therefore some causes the unfavorable factor of sperm development in the past, because the quality not affecting seminal fluid reduces the degree reached, especially do not make sperm quantity be reduced to and cause sterile threshold value, and can normal reproduction.But now along with the minimizing gradually of mankind spermatozoon density, any reason affecting semen quality particularly sperm development all may cause sterile.Wherein varicocele (varicocele, VC) has caused the concern of scholars, by the most important reason of the World Health Organization (WHO) as male sterility.Male sterility patient according to foreign statistic document announcement about 30% is associated with varicocele, and the domestic sickness rate be reported as wherein in Infertility male is 19 ~ 41%.
The traditional Chinese medical science, to the understanding of male infertility and treatment, has long history and abundant intension and experience, also also has full and accurate summary to varicocele simultaneously.As ancient books was once recorded: all Mr. and Mrs do not take contraceptives in more than 2 years after marriage, and wife's side unpregnancy person, or once had to breed and do not breed for latter 2 years again, its reason belongs to male person, is " loss of fecundity ", " asking heir " etc.Along with Chinese medicine development in recent years, the research of Chinese traditional treatment infertility and curative effect are subject to attracting attention of common people.
The treatment main method of current VC is operative treatment, modus operandi also has multiple, comprise various open surgery conventional clinically, although a lot of scholar has done a large amount of improvement at operation skill and position, but its larger wound is its maximum shortcoming, various open surgery be it is generally acknowledged that the high ligation of spermatic vein is curative effect guarantee certainly, carrying out of laparoscopic surgery, not only can the internal spermatic vein of high ligation bilateral, and by laparoscopically amplification, fine dissection can be accomplished, whole ligation internal spermatic vein can be guaranteed, avoid ligation incomplete, therefore surgical effect can be ensured better, there is wound simultaneously little, post-operative recovery is fast, hospital stays is short, the features such as relative costs is low.But, comprise the various operation for the treatment of VC of peritoneoscope high ligation of spermatic vein operation, although the semen quality of most of patient can be made to make moderate progress, because of the opportunity of operation of patient and the impact of other many factors, the semen quality of some patients improves undesirable.
Summary of the invention
For solving the technical problem of above-mentioned existence, the invention provides a kind of the kidney invigorating and essence nourishing cream side, be mainly used in the aftertreatment of varicocele operation, by contrasting with postoperative untreated patient, after operation in patients, taking the kidney invigorating and essence nourishing cream, having the effect of highly significant for improving semen quality, and postoperative complication and drug reaction incidence rate extremely low, unguentum is easy to carry and takes in time, and being conducive to postoperative treatment, is the therapeutic scheme that the dysspermatism caused by varicocele is more optimized.
For achieving the above object, the technical solution adopted in the present invention is:
A kind of the kidney invigorating and essence nourishing cream side, is made up of the raw material of Chinese medicine of following weight proportion: Herba Epimedii 10-20g, Radix Rehmanniae Preparata 10-20g, stir-baking RADIX MORINDAE after sprinking salt solution sky 5-15g, Fructus Lycii 12-18g, Semen Cuscutae 10-20g, Semen Plantaginis 8-15g, Fructus Schisandrae Chinensis 5-16g, Fructus Rubi 10-20g, Herba Cistanches 5-15g, Semen Astragali Complanati 5-12g, Radix Polygoni Multiflori Preparata 10-20g, Colla cornus cervi 10-15g, Radix Cynanchi Paniculati 25-35g, Radix Glycyrrhizae 5-12g.
A kind of ointment manufacture method of the kidney invigorating and essence nourishing cream side, by above-mentioned raw material of Chinese medicine Herba Epimedii 10-20g, Radix Rehmanniae Preparata 10-20g, stir-baking RADIX MORINDAE after sprinking salt solution sky 5-15g, Fructus Lycii 12-18g, Semen Cuscutae 10-20g, Semen Plantaginis 8-15g, Fructus Schisandrae Chinensis 5-16g, Fructus Rubi 10-20g, Herba Cistanches 5-15g, Semen Astragali Complanati 5-12g, Radix Polygoni Multiflori Preparata 10-20g, Radix Cynanchi Paniculati 25-35g, Radix Glycyrrhizae 5-12g soaks 10-14 hour, then put in special marmite and decoct, supernatant is gone to concentrate by just decocting to boil medicine after juice leaves standstill filtering-depositing with two, medicine juice after concentrated is poured in pot, carry out evaporation and concentration, form concentrated clear paste, steam molten and open Colla cornus cervi 10-15g, and pour in clear paste to be placed on little fire together with Mel and slowly temper, until become paste.
The present invention is the medicine that emphasis adds invigorating kidney, promoting blood circulation removing toxic substances on the basis of WUZIYANZONG WAN conjunction side, and makes cream side and facilitate patient to take.WUZIYANZONG WAN is the Tang Dynasty famous tonic recipe, because its composition medicine is all plant seed, rich and matter profit, by subsidy essence in kidney, make gonepoiesis fill Sheng, add blood circulation promoting medicine and blood ventilation is lived, liver energy catharsis essence in kidney makes it excretion degree of having, reaching the object for the treatment of infertility, is " at all times seed first party " by praise.
In the present invention, the pharmacologic effect of each raw material of Chinese medicine is as follows:
Herba Epimedii: acrid in the mouth, sweet, warm in nature, returns liver, kidney two warp.TAO Hong-Jing was once said: " taking this makes people be well negative and positive ".There is excessive sheep in the north, western river, closes for hundred times on the one, caused by the lid food leaves of pulse plants, and therefore named Herba Epimedii.Compendium of Material Medica is said: " Herba Epimedii person, does not warm in naturely tremble with fear, can beneficial vital essence, and insufficiency of kidney-YANG person should it ".Can with the compatibility such as Radix Morindae Officinalis, Semen Cuscutae.Modern medicine study confirms that Herba Epimedii stem and leaf contains icariine and volatile oil, and can strengthen hypothalamic pituitary gonadal axis and adrenal cortex axle, have the effect of androgen sample, its effect is better than Gecko and Hippocampus.Experiment proves: Herba Epimedii significantly can promote the growth of the Accessory sexual glands such as young mice epididymis and seminal vesicle, and can promote gonepoiesis, and after seminal vesicle is full of, sensation is neural, the generation wish of indirect excitation.Meanwhile, Herba Epimedii can also suppress vasomotor center, expansion peripheral vessels, remote-effects erection function; In addition Herba Epimedii is also very large on the impact of immune effect, and because epimedium brevicornum polysaccharide is contrary to Ts cytosis with icariine, therefore, Herba Epimedii has dual regulation to body's immunity, and antisperm antibody can be regulated the infringement of testis.
Radix Rehmanniae Preparata: sweet in the mouth; Warm in nature, to reach the same goal liver, kidney two warp with Herba Epimedii.There is effect that profit is cloudy, beneficial essence fills out marrow of enriching blood." book on Chinese herbal medicine is just " is on the books: " Radix Rehmanniae Preparata, property is put down, and abnormal smells from the patient is pure quiet, therefore can tonifying five ZANG-organs also Kidney-Yin, and in the dirty of many blood be will.Zhang Yuansu cloud: " thermally yellow the kidney invigorating, blood decline must with it .... subumbilical pain again, belong to kidney channel, non-Radix Rehmanniae Preparata can not remove, be the medicine of logical kidney also "." detailed outline " cloud: " fill out bone marrow, longue meat, promoting generation of vital essence and blood .... the old seven kinds of impairments of man five ".Modern pharmacological research also finds, Radix Rehmanniae Preparata has the effect of nourishing kidney yin, simultaneously containing iridoid constituents, be separated and obtained rehmannioside (rehmannioside) A, B, C, D, the tens of constituent such as Herba Leonuri glycoside (leonuride), aucubin (aucubin), catalpol (catalpol), obviously can increase the activity of animal serum Glutathione Peroxidase (GSH-Px); Reduce the content of lipid peroxide in serum. the activity of superoxide dismutase in blood (SOD) can be made to have rising to a certain degree.
Radix Morindae Officinalis: acrid-sweet flavor; Warm in nature, also return liver, kidney two warp, there is effect of reinforcing the kidney and supporting YANG, bone and muscle strengthening, expelling wind and removing dampness." Bencao Jingshu " was once recorded: " Radix Morindae Officinalis performance subsidy Yuanyang, condition true strength must be mended, and evil peace stayed, and this is so heal strong wind pathogen also "." main impotence does not rise, bone and muscle strengthening, settling five organs, and invigorating middle warmer increases will QI invigorating person, be spleen, kidney two through support "." and mend five kinds of over strain, benefit essence, sharp man person, the labor of the five internal organs, kidney is master for it, and the therapeutic method to keep the adverse QI flowing downwards then fire is fallen, then water liter falls in fire, the mutual residence of negative and positive, keeping a sound mind, therefore main kidney qi is grown, and Yuanyang benefit is contained, and all void is patient, does not ask it move back and move back "." book on Chinese herbal medicine converge ": " Radix Morindae Officinalis is the medicine of kidney channel blood system, top capping help Yuanyang then gastric qi grow, all void is from moving back ".Kidney channel is entered arbitrarily in stir-baking RADIX MORINDAE after sprinking salt solution sky, and the kidney invigorating merit is strong, infertile for deficiency of the kidney sun beach wormwood, premature ejaculation.Modern pharmacology confirms: Radix Morindae Officinalis is containing multiple anthraquinone component: as Rubiadin (rubiadin), 2-hydroxyl methylol anthraquinone (2-hydroxy-3-hydrox-ymethylanthraquinone) etc., has effects such as increasing immunity, promotion sexual organ development, resisting fatigue, promotion Corticosterone secretion and antiinflammatory.
Herba Epimedii and Radix Rehmanniae Preparata share, the kidney invigorating, enrich blood, beneficial essence combines, the two is monarch drug altogether, and both Radix Morindae Officinalis and Herba Epimedii nature and flavor are close, all can kidney-replenishing.But Herba Epimedii is comparatively strong at pungent, using warming therapy, therefore the power of its pungent loose tonifying YANG is higher, and warming middle-JIAO residence is dry, and Papillary medicine has one slow, one high a, profit, a dry difference, therefore is ministerial drug.
WUZIYANZONG WAN: have Fructus Lycii, Semen Cuscutae, Semen Plantaginis, Fructus Schisandrae Chinensis, Fructus Rubi five tastes medicine in side, it derives from Lee stile of the Ming Dynasty and writes in " Elementary Medicine ".Thoroughly when Ming Dynasty is opened once to say: " man takes this medicine and can add essence and mend marrow, dredge sharp kidney qi, and see and pay no attention to part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels cold and heat and asthenia and sthenia, the equal self energy of clothes is put down secret ".The five kinds of Chinese medicine of this prescription pill all uses seed fraction, therefore claims WUZIYANZONG WAN, is mainly used in improving semen quality, treatment infertility.
Fructus Lycii: sweet in the mouth; Property is put down.Return Liver Channel, kidney, lung meridian.There is effect of nourishing the liver, nourishing kidney, lung moistening.Be mainly used in caused by liver and kidney deficiency, have a dizzy spell, the illness such as impotence and seminal emission, cough due to consumptive disease." book on Chinese herbal medicine converges and says ": can strengthen lean god, the full essence of god is sufficient.
Semen Cuscutae: acrid in the mouth, sweet, slightly warm in nature; Return liver,kidney,spleen warp; Gas and and property delay, can float and also can sink.There is effect of the kidney invigorating and essence nourishing, the solid tire of spleen invigorating, nourishing the liver to improve visual acuity." herbal classic is met former " is recorded: " Semen Cuscutae, its merit is specially in beneficial marrow, and hard muscles and bones, only spermatorrhea, stem essence of trembling with fear goes out.
Semen Plantaginis: sweet in the mouth, light; Cold nature.Return lung meridian, kidney channel, Liver Channel, urinary bladder channel." book on Chinese herbal medicine converges and says " is recorded: Semen Plantaginis, row liver dredges kidney, freely strongly fragrant and positive, with kidney-reinforcing drug use, makes reinforcing YIN-essence have son.
Fructus Schisandrae Chinensis: warm in nature; Sour, sweet; GUIXIN, lung, kidney channel.There is convergence astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, effect of kidney calming." Amplification on Materia Medica addendum ": the modern meaning five tastes, does not know in fact, can receive lung qi greatly with it, it should have the merit of the kidney invigorating.
Fructus Rubi: sour in the mouth, returns liver, kidney two warp, has invigorating the liver and kidney, urine reducing, supporing yang, controlling nocturnal emission with astringent drugs, effect of improving eyesight." property of medicine opinion " once described: " main man's kidney-jing deficiency exhausts.
Herba Cistanches: sweet in the mouth, salty, warm in nature, returns kidney, large intestine channel.There is kidney-replenishing, benefiting essence-blood effect.Also known as Herba Stellariae Saxatilis, at present in the world close to frequently facing extinct specie, medical value is very high, have the good reputation of " desert Radix Ginseng ", it is the medicine that in more than 60 kind of traditional tonic medicine finding of China, grade is the highest, containing the rare nutritious tonifying composition of a large amount of aminoacid, vitamin and mineral, confirm there is great tonification effect to sexual organs such as male's kidney, testis, penis, spongy bodies after deliberation, also very good to sexual impotence, premature ejaculation effect.Once on the books in supplement to the Herbal: " Herba Cistanches three money, three decoct a system, and hot drink takes it, and penis does not wane all the life ".
Semen Astragali Complanati: sweet in the mouth, warm in nature, has effect of the kidney invigorating, benefit essence, controlling nocturnal emission with astringent drugs, arresting seminal emission.History tree all describes these effects of Semen Astragali Complanati, has benefit essence and random sun, the characteristic of YANG invigorating and not random body.
Radix Polygoni Multiflori Preparata: sweet in the mouth and hardship, puckery; Property is tepor; Liver, kidney two warp is equally returned with above-mentioned most drug.Have obvious invigorating the liver and kidney, benefiting essence-blood, calm the nerves, black hair, the only effect such as juice, bone and muscle strengthening.Compendium of Material Medica was once recorded: Radix Polygoni Multiflori energy " improving healthy complexion, uses long muscles and bones for a long time, beneficial marrow for the beneficial motive, black beard and hair, prolongs life not old ".Modern pharmacology research confirmation has promote hemopoietic function, strengthen immunologic function, blood fat reducing and atherosclerosis, protect the liver, the function such as slow down aging, promotion acth secretion.
Colla cornus cervi: salty in the mouth and warm in nature, also returns liver, kidney two warp, has temperature compensation Liver and kidney, beneficial intensive culture blood.In addition in this research because of the characteristic of its glue, for the receipts cream in cream side's manufacturing process.There is reinforcing the kidney and supporting YANG, be all adjuvant drug with above several drugs.
Radix Cynanchi Paniculati: acrid in the mouth and warm in nature, returns Liver Channel, stomach two warp.There is blood circulation promoting and blood stasis dispelling, the effect of removing toxic substances of dispeling the wind.Doctor trained in Western medicine pharmacology is thought, Radix Cynanchi Paniculati has estrogen-like effects, energy Stimulation of Pituitary Gland, interrenal system, and strengthen its effect, thus can react by Immunosuppression, it is improved microcirculation, antiinflammation simultaneously, positive for the AsAb caused by inflammation, can accelerate to play the effect eliminated.
Radix Glycyrrhizae: sweet in the mouth is sweet, property is gentle, enters the heart, lung, spleen, stomach four warp.There is QI invigorating invigorating middle warmer, relieving spasm to stop pain; , eliminating fire and detoxication, nourishing the lung to arrest cough, coordinating the actions of various ingredients in a prescription effect, " book on Chinese herbal medicine converge with speech " is recorded: Radix Glycyrrhizae, and middle QI invigorating, the medicine of tonify deficiency removing toxic substances is also.Modern pharmacology research also confirms, Radix Glycyrrhizae has Detoxication, and to some alimentary toxicosis, drug intoxication, interior metabolism product is poisoning all has certain detoxification ability.The active ingredient of its Detoxication is glycyrrhizin contained in Radix Glycyrrhizae, detoxication mechanisms is that glycyrrhizin has adsorption to noxious substance, glycyrrhizin hydrolyzate glucuronic acid can be combined with poisonous substance, glycyrrhizin have the effect of adrenocortical hormone sample simultaneously, can strengthen the result of the aspect combined factors effects such as the function of detoxification of liver.The present invention is mainly in order to be in harmonious proportion the property of medicine for making medicine.
Traditional Chinese medical science the kidney invigorating and essence nourishing cream side of the present invention, for the improvement successful of the postoperative semen quality of varicocele, can significantly improve sperm concentration, improve the vigor of sperm, improve the pregnancy rate of patient, make unguentum and be convenient for carrying and store, facilitate patient to adhere to taking, guarantee therapeutic effect.
Detailed description of the invention
describe the present invention below in conjunction with specific embodiment:
The technical solution used in the present invention is: a kind of the kidney invigorating and essence nourishing cream side, is made up of the raw material of Chinese medicine of following weight proportion: Herba Epimedii 10-20g, Radix Rehmanniae Preparata 10-20g, stir-baking RADIX MORINDAE after sprinking salt solution sky 5-15g, Fructus Lycii 12-18g, Semen Cuscutae 10-20g, Semen Plantaginis 8-15g, Fructus Schisandrae Chinensis 5-16g, Fructus Rubi 10-20g, Herba Cistanches 5-15g, Semen Astragali Complanati 5-12g, Radix Polygoni Multiflori Preparata 10-20g, Colla cornus cervi 10-15g, Radix Cynanchi Paniculati 25-35g, Radix Glycyrrhizae 5-12g.
A kind of ointment manufacture method of the kidney invigorating and essence nourishing cream side, by above-mentioned raw material of Chinese medicine Herba Epimedii 10-20g, Radix Rehmanniae Preparata 10-20g, stir-baking RADIX MORINDAE after sprinking salt solution sky 5-15g, Fructus Lycii 12-18g, Semen Cuscutae 10-20g, Semen Plantaginis 8-15g, Fructus Schisandrae Chinensis 5-16g, Fructus Rubi 10-20g, Herba Cistanches 5-15g, Semen Astragali Complanati 5-12g, Radix Polygoni Multiflori Preparata 10-20g, Radix Cynanchi Paniculati 25-35g, Radix Glycyrrhizae 5-12g soaks 10-14 hour, then put in special marmite and decoct, supernatant is gone to concentrate by just decocting to boil medicine after juice leaves standstill filtering-depositing with two, medicine juice after concentrated is poured in pot, carry out evaporation and concentration, form concentrated clear paste, steam molten and open Colla cornus cervi, and pour in clear paste to be placed on little fire together with Mel and slowly temper, until become paste.
Embodiment 1:
Take Herba Epimedii 10g, Radix Rehmanniae Preparata 20g, stir-baking RADIX MORINDAE after sprinking salt solution sky 5g, Fructus Lycii 18g, Semen Cuscutae 10g, Semen Plantaginis 15g, Fructus Schisandrae Chinensis 5g, Fructus Rubi 20g, Herba Cistanches 5g, Semen Astragali Complanati 12g, Radix Polygoni Multiflori Preparata 10g, Colla cornus cervi 15g, Radix Cynanchi Paniculati 25g, Radix Glycyrrhizae 12g, be made into unguentum.
Embodiment 2:
Take Herba Epimedii 20g, Radix Rehmanniae Preparata 10g, stir-baking RADIX MORINDAE after sprinking salt solution sky 15g, Fructus Lycii 12g, Semen Cuscutae 20g, Semen Plantaginis 8g, Fructus Schisandrae Chinensis 16g, Fructus Rubi 10g, Herba Cistanches 15g, Semen Astragali Complanati 5g, Radix Polygoni Multiflori Preparata 20g, Colla cornus cervi 10g, Radix Cynanchi Paniculati 35g, Radix Glycyrrhizae 5g, be made into unguentum.
Embodiment 3:
Take Herba Epimedii 12g, Radix Rehmanniae Preparata 18g, stir-baking RADIX MORINDAE after sprinking salt solution sky 10g, Fructus Lycii 16g, Semen Cuscutae 13g, Semen Plantaginis 10g, Fructus Schisandrae Chinensis 8g, Fructus Rubi 16g, Herba Cistanches 10g, Semen Astragali Complanati 8g, Radix Polygoni Multiflori Preparata 15g, Colla cornus cervi 12g, Radix Cynanchi Paniculati 32g, Radix Glycyrrhizae 7g, be made into unguentum.
Embodiment 4:
Take Herba Epimedii 18g, Radix Rehmanniae Preparata 12g, stir-baking RADIX MORINDAE after sprinking salt solution sky 12g, Fructus Lycii 15g, Semen Cuscutae 12g, Semen Plantaginis 10g, Fructus Schisandrae Chinensis 10g, Fructus Rubi 10g, Herba Cistanches 8g, Semen Astragali Complanati 10g, Radix Polygoni Multiflori Preparata 12g, Colla cornus cervi 12g, Radix Cynanchi Paniculati 30g, Radix Glycyrrhizae 10g, be made into unguentum.
Embodiment 5:
Take Herba Epimedii 15g, Radix Rehmanniae Preparata 15g, stir-baking RADIX MORINDAE after sprinking salt solution sky 10g, Fructus Lycii 15g, Semen Cuscutae 15g, Semen Plantaginis 10g, Fructus Schisandrae Chinensis 10g, Fructus Rubi 15g, Herba Cistanches 10g, Semen Astragali Complanati 9g, Radix Polygoni Multiflori Preparata 15g, Colla cornus cervi 12g, Radix Cynanchi Paniculati 30g, Radix Glycyrrhizae 9g, be made into unguentum.
Embodiment 6:
Take Herba Epimedii 15g, Radix Rehmanniae Preparata 16g, stir-baking RADIX MORINDAE after sprinking salt solution sky 12g, Fructus Lycii 14g, Semen Cuscutae 18g, Semen Plantaginis 14g, Fructus Schisandrae Chinensis 15g, Fructus Rubi 15g, Herba Cistanches 12g, Semen Astragali Complanati 6g, Radix Polygoni Multiflori Preparata 18g, Colla cornus cervi 14g, Radix Cynanchi Paniculati 28g, Radix Glycyrrhizae 8g, be made into unguentum.
Embodiment 7:
Take Herba Epimedii 18g, Radix Rehmanniae Preparata 12g, stir-baking RADIX MORINDAE after sprinking salt solution sky 13g, Fructus Lycii 14g, Semen Cuscutae 15g, Semen Plantaginis 13g, Fructus Schisandrae Chinensis 6g, Fructus Rubi 18g, Herba Cistanches 10g, Semen Astragali Complanati 10g, Radix Polygoni Multiflori Preparata 16g, Colla cornus cervi 12g, Radix Cynanchi Paniculati 34g, Radix Glycyrrhizae 8g, be made into unguentum.
When clinical treatment male infertility patient, using the kidney invigorating and essence nourishing to control, cream side's treatment peritoneoscope high ligation of spermatic vein postoperative semen quality is not good compares, and treatment group is better than surgery alone therapeutic effect.
Clinical case:
Case selection inclusive criteria:
1. after marriage can normal sexuality.2. the intended pregnancy time is greater than 1 year, and does not take any contraceptives; Or the common childbearing history of existing man and wife, propose planned parenthood, and the enforcement time was more than 1 year unpregnancy.3. the wife's side checks no abnormality seen.4. bridegroom's or husband's side Sperm recovery is abnormal, sperm concentration < 20 × 10
6/ ml, and a level sperm ratio < 25%, or a+b level sperm ratio < 50%.And with varicocele and exist backflow.5. this research of voluntary participation also positive partner treatment person.
Exclusion standard:
1. the other diseases that semen quality declines can be caused, as bilateral testes atrophy, small testopathy, deferent duct is inaccessible; Seminal vesicle, prostate, cowper gland illness; Retrograde ejaculation, anejaculation etc.2. obvious spiritual abnormal emotion-thought.3. there is erection disturbance, cannot normal sexuality person be carried out.4. spouse suffers from reproductive system disease and the whole body other system sickness influence person of becoming pregnant.
Case clinical data:
The patient that 116 examples are chief complaint with the male infertility that VC causes is divided into two groups at random, treatment group 67 example, matched group 59 example.Age in 24-40 year, and the age, the course of disease, the state of an illness, simultaneous phenomenon through statistical analysis there was no significant difference (P>0.05), there is comparability.
Before treatment, comparative analysis is as follows:
Table 1: before two groups of patient treatments, age, the course of disease, internal spermatic vein internal diameter compare
| Group | Number of cases | Age | The course of disease (year) | Internal spermatic vein internal diameter (mm) |
| Treatment group | 67 | 31.80±5.26 | 5.25±3.32 | 2.53±0.32 |
| Matched group | 59 | 31.45±6.24 | 5.41±3.46 | 2.51±0.33 |
Patient age t checks, and draws age average and standard deviation, and calculates P > 0.05, has comparability; Internal spermatic vein internal diameter t checks, and draw spermatic vein internal diameter average and standard deviation internal diameter, P > 0.05 has comparability; Adopt X 2 test, draw severity extent, P > 0.05, the course of disease has comparability.
Table 2 liang group patient treatment Sperm recovery result after 3 months
| Group | Number of cases | Sperm concentration | A level sperm ratio | A+B level sperm ratio |
| Treatment group | 67 | 21.26±7.22 | 25.61±9.32 | 36.53±11.36 |
| Matched group | 59 | 18.18±6.94 | 22.47±9.42 | 32.58±10.33 |
Treat conventional semen efamination after 3 months, find the change of sperm concentration, A level sperm ratio, A+B level sperm ratio, above-mentioned indices uses spss 19.0 statistical software to carry out data analysis, result shows, and treatment group comparatively matched group indices all has statistical significance (P < 0.05).
Table 3 liang group patient treatment Sperm recovery result after 6 months
| Group | Number of cases | Sperm concentration | A level sperm ratio | A+B level sperm ratio |
| Treatment group | 67 | 38.26±14.22 | 34.67±11.43 | 43.58±12.16 |
| Matched group | 59 | 22.18±10.27 | 24.35±10.64 | 34.64±10.63 |
Treat conventional semen efamination after 6 months, find the change of sperm concentration, A level sperm ratio, A+B level sperm ratio, above-mentioned indices uses spss 19.0 statistical software to carry out data analysis, result shows, and treatment group comparatively matched group indices all has statistical significance (P < 0.01).
Table 4 treatment group patient treatment is Sperm recovery result after 3 months and after 6 months
| Group | Sperm concentration | A level sperm ratio | A+B level sperm ratio |
| Treatment group 3 months | 21.26±7.22 | 25.61±9.32 | 36.53±11.36 |
| Treatment group 6 months | 38.26±14.22 | 34.67±11.43 | 43.58±12.16 |
Treatment group conventional semen efamination in 3 months, 6 months, find the change of sperm concentration, A level sperm ratio, A+B level sperm ratio, make moderate progress, above-mentioned indices display, spss 19.0 statistical software is used to carry out data analysis, result shows, and treatment group comparatively matched group indices all has statistical significance (P < 0.01).
Table 5 matched group patient treatment is Sperm recovery result after 3 months and after 6 months
| Group | Sperm concentration | A level sperm ratio | A+B level sperm ratio |
| Matched group 3 months | 18.18±6.94 | 22.47±9.42 | 32.58±10.33 |
| Matched group 6 months | 22.18±10.27 | 24.35±10.64 | 34.64±10.63 |
Matched group conventional semen efamination in 3 months, 6 months, find the change of sperm concentration, A level sperm ratio, A+B level sperm ratio, make moderate progress, above-mentioned indices display, spss 19.0 statistical software is used to carry out data analysis, result shows, and treatment group is the equal not statistically significant of matched group indices (P > 0.05) comparatively.
Table 6 treat in complication situation referring to
| Group | Mumu | Pneumoscrotum | Atrophy of testis | Hydrocele of tunica vaginalis | Gastrointestinal reaction |
| Treatment group | 1 | 1 | 0 | 2 | 0 |
| Matched group | 0 | 2 | 0 | 0 | 2 |
There is mumu 1 example after all corrective surgeries, pneumoscrotum 3 example, atrophy of testis 0 example, hydrocele of tunica vaginalis 2 example, have the slight bad habit of 2 example after treating oral kidney-tonifying sperm-generating cream after surgery, without vomiting, all can tolerate completed treatment.
In sum, by the semen quality patients with abnormal that 116 routine varicoceles cause, 2 groups are divided at random according to Principle of Statistics.Wherein varicocele ligation under treatment group 67 example employing peritoneoscope, within postoperative 1 week, start to apply the treatment of the kidney invigorating and essence nourishing cream side, matched group 59 example is simple adopts high ligation of spermatic vein treatment, opponent's 3 months after operation, the relevant data of 6 months Semen routione carries out statistical analysis research and finds: 3 months after operation, after 6 months Laparoscopic varicocele ligation+take the kidney invigorating and essence nourishing cream side, and adopt separately laparoscopic surgical procedure dysspermatism merging VC all can improve sperm concentration in Semen routione, A level sperm ratio, A+B sperm ratio, but treatment group is because of after taking the kidney invigorating and essence nourishing, all be improved than the indices of matched group 3 months and 6 months, the improvement of especially postoperative 6 months is more obvious.In addition, the complication of two groups of corrective surgeries treatment and drug reaction incidence rate extremely low.Therefore can think, cause dysspermatism to cause the Therapeutic Method of infertility for VC, while peritoneoscope high ligation of spermatic vein, the treatment of oral the kidney invigorating and essence nourishing cream side is the therapeutic scheme optimized.
Certainly, above-mentioned explanation is not limitation of the present invention, and the present invention is also not limited in above-mentioned citing, and the change that those skilled in the art make in essential scope of the present invention, remodeling, interpolation or replacement also should belong to protection scope of the present invention.
Claims (2)
1. a kidney invigorating and essence nourishing cream side, it is characterized in that, be made up of the raw material of Chinese medicine of following weight proportion: Herba Epimedii 10-20g, Radix Rehmanniae Preparata 10-20g, stir-baking RADIX MORINDAE after sprinking salt solution sky 5-15g, Fructus Lycii 12-18g, Semen Cuscutae 10-20g, Semen Plantaginis 8-15g, Fructus Schisandrae Chinensis 5-16g, Fructus Rubi 10-20g, Herba Cistanches 5-15g, Semen Astragali Complanati 5-12g, Radix Polygoni Multiflori Preparata 10-20g, Colla cornus cervi 10-15g, Radix Cynanchi Paniculati 25-35g, Radix Glycyrrhizae 5-12g.
2. the ointment manufacture method of a kidney invigorating and essence nourishing cream side as claimed in claim 1, it is characterized in that, by above-mentioned raw material of Chinese medicine Herba Epimedii 10-20g, Radix Rehmanniae Preparata 10-20g, stir-baking RADIX MORINDAE after sprinking salt solution sky 5-15g, Fructus Lycii 12-18g, Semen Cuscutae 10-20g, Semen Plantaginis 8-15g, Fructus Schisandrae Chinensis 5-16g, Fructus Rubi 10-20g, Herba Cistanches 5-15g, Semen Astragali Complanati 5-12g, Radix Polygoni Multiflori Preparata 10-20g, Radix Cynanchi Paniculati 25-35g, Radix Glycyrrhizae 5-12g soaks 10-14 hour, then put in special marmite and decoct, supernatant is gone to concentrate by just decocting to boil medicine after juice leaves standstill filtering-depositing with two, medicine juice after concentrated is poured in pot, carry out evaporation and concentration, form concentrated clear paste, steam molten and open Colla cornus cervi 10-15g, and pour in clear paste to be placed on little fire together with Mel and slowly temper, until become paste.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105194092A (en) * | 2015-11-12 | 2015-12-30 | 何再亮 | Capsule capable of reinforcing kidneys and strengthening yang |
| CN105327002A (en) * | 2015-11-12 | 2016-02-17 | 何再亮 | Kidney-tonifying oral liquid |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1876089A (en) * | 2005-06-09 | 2006-12-13 | 张友生 | A pharmaceutical composition for treating kidney-qi deficiency syndrome and preparation method thereof |
| CN101810763A (en) * | 2010-04-20 | 2010-08-25 | 烟台新安男科医院 | Chinese medicinal preparation for curing male infertility and sexual dysfunction and preparation method thereof |
| CN104173736A (en) * | 2014-06-29 | 2014-12-03 | 苟晓龙 | Kidney-tonifying sperm-growing traditional Chinese medicinal composition |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1876089A (en) * | 2005-06-09 | 2006-12-13 | 张友生 | A pharmaceutical composition for treating kidney-qi deficiency syndrome and preparation method thereof |
| CN101810763A (en) * | 2010-04-20 | 2010-08-25 | 烟台新安男科医院 | Chinese medicinal preparation for curing male infertility and sexual dysfunction and preparation method thereof |
| CN104173736A (en) * | 2014-06-29 | 2014-12-03 | 苟晓龙 | Kidney-tonifying sperm-growing traditional Chinese medicinal composition |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105194092A (en) * | 2015-11-12 | 2015-12-30 | 何再亮 | Capsule capable of reinforcing kidneys and strengthening yang |
| CN105327002A (en) * | 2015-11-12 | 2016-02-17 | 何再亮 | Kidney-tonifying oral liquid |
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