CN104686516B - A kind of bactericidal composition containing Hexanaphthene flusulfamide - Google Patents
A kind of bactericidal composition containing Hexanaphthene flusulfamide Download PDFInfo
- Publication number
- CN104686516B CN104686516B CN201510073038.6A CN201510073038A CN104686516B CN 104686516 B CN104686516 B CN 104686516B CN 201510073038 A CN201510073038 A CN 201510073038A CN 104686516 B CN104686516 B CN 104686516B
- Authority
- CN
- China
- Prior art keywords
- hexanaphthene flusulfamide
- active component
- disease
- composition containing
- active
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- XDTMQSROBMDMFD-UHFFFAOYSA-N Cyclohexane Chemical compound C1CCCCC1 XDTMQSROBMDMFD-UHFFFAOYSA-N 0.000 title claims abstract description 79
- GNVDAZSPJWCIQZ-UHFFFAOYSA-N flusulfamide Chemical compound ClC1=CC([N+](=O)[O-])=CC=C1NS(=O)(=O)C1=CC=C(Cl)C(C(F)(F)F)=C1 GNVDAZSPJWCIQZ-UHFFFAOYSA-N 0.000 title claims abstract description 79
- 239000000203 mixture Substances 0.000 title claims abstract description 45
- 230000000844 anti-bacterial effect Effects 0.000 title claims abstract description 19
- 201000010099 disease Diseases 0.000 claims abstract description 44
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims abstract description 44
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 claims abstract description 17
- 239000000375 suspending agent Substances 0.000 claims description 18
- 239000003094 microcapsule Substances 0.000 claims description 14
- 241000221785 Erysiphales Species 0.000 claims description 13
- 239000000839 emulsion Substances 0.000 claims description 12
- 235000007164 Oryza sativa Nutrition 0.000 claims description 10
- 235000009566 rice Nutrition 0.000 claims description 10
- 239000003795 chemical substances by application Substances 0.000 claims description 9
- JEIPFZHSYJVQDO-UHFFFAOYSA-N iron(III) oxide Inorganic materials O=[Fe]O[Fe]=O JEIPFZHSYJVQDO-UHFFFAOYSA-N 0.000 claims description 9
- 206010039509 Scab Diseases 0.000 claims description 8
- 239000004530 micro-emulsion Substances 0.000 claims description 7
- 239000000725 suspension Substances 0.000 claims description 7
- 239000004563 wettable powder Substances 0.000 claims description 7
- 239000004562 water dispersible granule Substances 0.000 claims description 6
- 241001530056 Athelia rolfsii Species 0.000 claims description 5
- 235000006484 Paeonia officinalis Nutrition 0.000 claims description 5
- 241000233679 Peronosporaceae Species 0.000 claims description 5
- 240000008042 Zea mays Species 0.000 claims description 5
- 235000016383 Zea mays subsp huehuetenangensis Nutrition 0.000 claims description 5
- 235000002017 Zea mays subsp mays Nutrition 0.000 claims description 5
- 235000009973 maize Nutrition 0.000 claims description 5
- 241000918585 Pythium aphanidermatum Species 0.000 claims description 4
- 230000001580 bacterial effect Effects 0.000 claims description 4
- 240000007594 Oryza sativa Species 0.000 claims 1
- 244000170916 Paeonia officinalis Species 0.000 claims 1
- 230000002195 synergetic effect Effects 0.000 abstract description 21
- DHVLDKHFGIVEIP-UHFFFAOYSA-N 2-bromo-2-(bromomethyl)pentanedinitrile Chemical compound BrCC(Br)(C#N)CCC#N DHVLDKHFGIVEIP-UHFFFAOYSA-N 0.000 abstract description 18
- 230000000694 effects Effects 0.000 abstract description 17
- 230000003115 biocidal effect Effects 0.000 abstract description 16
- FFSJPOPLSWBGQY-UHFFFAOYSA-N triazol-4-one Chemical compound O=C1C=NN=N1 FFSJPOPLSWBGQY-UHFFFAOYSA-N 0.000 abstract description 16
- 239000002718 pyrimidine nucleoside Substances 0.000 abstract description 15
- 150000001875 compounds Chemical class 0.000 abstract description 9
- 230000000855 fungicidal effect Effects 0.000 abstract description 2
- 238000001228 spectrum Methods 0.000 abstract description 2
- 239000002131 composite material Substances 0.000 abstract 1
- 238000005406 washing Methods 0.000 abstract 1
- 239000003814 drug Substances 0.000 description 28
- 238000013329 compounding Methods 0.000 description 24
- 230000003449 preventive effect Effects 0.000 description 21
- 238000002474 experimental method Methods 0.000 description 17
- 238000012360 testing method Methods 0.000 description 17
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 17
- 239000012071 phase Substances 0.000 description 13
- 239000013530 defoamer Substances 0.000 description 12
- 241000209140 Triticum Species 0.000 description 11
- 235000021307 Triticum Nutrition 0.000 description 11
- 239000002270 dispersing agent Substances 0.000 description 11
- 230000002528 anti-freeze Effects 0.000 description 10
- 239000002904 solvent Substances 0.000 description 10
- 241000209094 Oryza Species 0.000 description 9
- 239000008367 deionised water Substances 0.000 description 9
- 229910021641 deionized water Inorganic materials 0.000 description 9
- 239000003995 emulsifying agent Substances 0.000 description 9
- 239000000080 wetting agent Substances 0.000 description 9
- 239000002562 thickening agent Substances 0.000 description 8
- 231100000820 toxicity test Toxicity 0.000 description 8
- 238000000034 method Methods 0.000 description 7
- 239000000575 pesticide Substances 0.000 description 7
- 239000000463 material Substances 0.000 description 6
- 230000002265 prevention Effects 0.000 description 6
- 241000894006 Bacteria Species 0.000 description 5
- 240000008067 Cucumis sativus Species 0.000 description 5
- 235000010799 Cucumis sativus var sativus Nutrition 0.000 description 5
- 235000009754 Vitis X bourquina Nutrition 0.000 description 5
- 235000012333 Vitis X labruscana Nutrition 0.000 description 5
- 240000006365 Vitis vinifera Species 0.000 description 5
- 235000014787 Vitis vinifera Nutrition 0.000 description 5
- -1 hexamethylene sulphur Chemical compound 0.000 description 5
- 230000005764 inhibitory process Effects 0.000 description 5
- 235000017060 Arachis glabrata Nutrition 0.000 description 4
- 244000105624 Arachis hypogaea Species 0.000 description 4
- 235000010777 Arachis hypogaea Nutrition 0.000 description 4
- 235000018262 Arachis monticola Nutrition 0.000 description 4
- 241001157813 Cercospora Species 0.000 description 4
- 206010011732 Cyst Diseases 0.000 description 4
- 241000736199 Paeonia Species 0.000 description 4
- 238000004458 analytical method Methods 0.000 description 4
- 208000031513 cyst Diseases 0.000 description 4
- 229940079593 drug Drugs 0.000 description 4
- 238000013401 experimental design Methods 0.000 description 4
- 239000000945 filler Substances 0.000 description 4
- 229920002521 macromolecule Polymers 0.000 description 4
- JMANVNJQNLATNU-UHFFFAOYSA-N oxalonitrile Chemical compound N#CC#N JMANVNJQNLATNU-UHFFFAOYSA-N 0.000 description 4
- 239000002245 particle Substances 0.000 description 4
- 235000020232 peanut Nutrition 0.000 description 4
- 238000002360 preparation method Methods 0.000 description 4
- 206010067482 No adverse event Diseases 0.000 description 3
- 239000005864 Sulphur Substances 0.000 description 3
- 239000003905 agrochemical Substances 0.000 description 3
- 230000008485 antagonism Effects 0.000 description 3
- 239000008346 aqueous phase Substances 0.000 description 3
- 239000011230 binding agent Substances 0.000 description 3
- 239000007884 disintegrant Substances 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 239000003002 pH adjusting agent Substances 0.000 description 3
- 239000000843 powder Substances 0.000 description 3
- 239000007787 solid Substances 0.000 description 3
- 241000510928 Erysiphe necator Species 0.000 description 2
- 206010027146 Melanoderma Diseases 0.000 description 2
- 239000011149 active material Substances 0.000 description 2
- 150000001336 alkenes Chemical class 0.000 description 2
- 150000001412 amines Chemical class 0.000 description 2
- 239000012752 auxiliary agent Substances 0.000 description 2
- 238000000498 ball milling Methods 0.000 description 2
- 235000013339 cereals Nutrition 0.000 description 2
- 150000002148 esters Chemical class 0.000 description 2
- 238000009472 formulation Methods 0.000 description 2
- 230000009036 growth inhibition Effects 0.000 description 2
- 230000002045 lasting effect Effects 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 239000004094 surface-active agent Substances 0.000 description 2
- 230000001988 toxicity Effects 0.000 description 2
- 231100000419 toxicity Toxicity 0.000 description 2
- 230000001018 virulence Effects 0.000 description 2
- 240000002791 Brassica napus Species 0.000 description 1
- 235000006008 Brassica napus var napus Nutrition 0.000 description 1
- 244000025254 Cannabis sativa Species 0.000 description 1
- 241000395107 Cladosporium cucumerinum Species 0.000 description 1
- 241000219112 Cucumis Species 0.000 description 1
- 235000015510 Cucumis melo subsp melo Nutrition 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 241000221662 Sclerotinia Species 0.000 description 1
- FJJCIZWZNKZHII-UHFFFAOYSA-N [4,6-bis(cyanoamino)-1,3,5-triazin-2-yl]cyanamide Chemical compound N#CNC1=NC(NC#N)=NC(NC#N)=N1 FJJCIZWZNKZHII-UHFFFAOYSA-N 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 238000013019 agitation Methods 0.000 description 1
- 238000012271 agricultural production Methods 0.000 description 1
- 230000010165 autogamy Effects 0.000 description 1
- 239000003899 bactericide agent Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000000481 breast Anatomy 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 230000002508 compound effect Effects 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 239000002552 dosage form Substances 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 238000003912 environmental pollution Methods 0.000 description 1
- 210000003608 fece Anatomy 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 230000004907 flux Effects 0.000 description 1
- 229930182470 glycoside Natural products 0.000 description 1
- 150000002338 glycosides Chemical class 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 235000021374 legumes Nutrition 0.000 description 1
- 239000010871 livestock manure Substances 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 239000002420 orchard Substances 0.000 description 1
- 238000005453 pelletization Methods 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 238000003672 processing method Methods 0.000 description 1
- 125000000714 pyrimidinyl group Chemical group 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 229940124530 sulfonamide Drugs 0.000 description 1
- 150000003456 sulfonamides Chemical class 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- PHLBKPHSAVXXEF-UHFFFAOYSA-N trazodone Chemical compound ClC1=CC=CC(N2CCN(CCCN3C(N4C=CC=CC4=N3)=O)CC2)=C1 PHLBKPHSAVXXEF-UHFFFAOYSA-N 0.000 description 1
- 229960003991 trazodone Drugs 0.000 description 1
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses a kind of efficient bactericidal composite containing Hexanaphthene flusulfamide, the bactericidal composition containing active components A Yu active component B, active components A is selected from Hexanaphthene flusulfamide, and active component B is selected from following any one compound：Triazolone, antibiotic in pyrimidine nucleoside class, 2-cyano-3-amino-3-phenylancryic acetate, bromothalonil, and active components A and the weight ratio of active component B are 1: 60~80: 1.The present composition has greater activity to the multiple diseases in various crop, and with obvious synergistic effect, expands fungicidal spectrum.And with dosage is small, resistance of rainwater washing against, the characteristics of synergy is obvious.
Description
The application is divisional application, and original application is the patent application of Shaanxi Meibang Pesticide Co., Ltd.
" a kind of bactericidal composition containing Hexanaphthene flusulfamide ", the Application No. of original application：
2012103024795, original application day is 2012.08.23.
Technical field
The invention belongs to technical field of pesticide, it is related to a kind of bactericidal composition containing Hexanaphthene flusulfamide
Application in crop disease.
Technical background
Hexanaphthene flusulfamide chemical name：N- (2- trifluoromethyl-4-chlorophenyls)-a- oxocyclohexyls
Sulfonamide.It has stronger prevention, treatment and osmotically active, and has lasting effect higher.
It is bright through table of field test results, Hexanaphthene flusulfamide can effectively prevent and treat gray mold, sclerotinia rot of colza,
Cucumber Target Leaf Spot and scab.
In the real process of agricultural production, controlling disease is easiest to generate the problem that disease resists
The generation of the property of medicine.Different cultivars composition is compounded, and is to prevent and treat the very common method of resistance disease.
Heterogeneity is compounded, and judges that certain compounding is synergy, adds according to practical application effect
With still antagonism.In most cases, the compounding effect of agricultural chemicals is all additive effect,
The real compounding for having synergistic effect seldom, especially synergistic effect clearly, synergy ratio very
Compounding high is just less.Studied by inventor, find by Hexanaphthene flusulfamide and triazolone,
Antibiotic in pyrimidine nucleoside class, 2-cyano-3-amino-3-phenylancryic acetate, bromothalonil are mutually compounded, and are had within the specific limits very
Good synergistic effect, and about Hexanaphthene flusulfamide and triazolone, antibiotic in pyrimidine nucleoside class, cyanogen
The related compounding of alkene bacterium ester, bromothalonil, at present at home and abroad there is not yet relevant report.
The content of the invention
Have that synergistic function, use cost be low, preventive effect the purpose of the present invention is to propose to one kind
The good bactericidal composition containing Hexanaphthene flusulfamide.
The present invention is to be achieved through the following technical solutions：
A kind of bactericidal composition containing Hexanaphthene flusulfamide, containing active components A and active component B,
Active components A is 1: 60~80: 1, described active component with active component B weight ratio
A is selected from Hexanaphthene flusulfamide, and active component B is selected from triazolone, antibiotic in pyrimidine nucleoside class, cyanogen
One kind in alkene bacterium ester, bromothalonil；The preferably weight of active components A and active component B
Than being the ︰ 1 of 1 ︰ 40~60；More preferably Hexanaphthene flusulfamide and the weight ratio of triazolone is 1:
10~20: 1, Hexanaphthene flusulfamide is 1: 10~20 with the weight ratio of antibiotic in pyrimidine nucleoside class:
1, the weight ratio of Hexanaphthene flusulfamide and 2-cyano-3-amino-3-phenylancryic acetate is 1: 20~20: 1, Hexanaphthene flusulfamide with
The weight ratio of bromothalonil is 1: 10~20: 1；The most preferably weight of Hexanaphthene flusulfamide and triazolone
Than being 1: 4~9: 1, Hexanaphthene flusulfamide is 1 with the weight ratio of antibiotic in pyrimidine nucleoside class to amount:
4~9: 1, Hexanaphthene flusulfamide is 1: 9~9: 1, hexamethylene sulphur bacterium with the weight ratio of 2-cyano-3-amino-3-phenylancryic acetate
Amine is 1: 4~9: 1 with the weight ratio of bromothalonil.
The described bactericidal composition containing Hexanaphthene flusulfamide, composition is made wettable powder, water
Dispersible granule, suspending agent, aqueous emulsion, microemulsion, suspension emulsion, microcapsule suspending agent, micro-capsule hang
Floating-suspending agent, can also be made aqua.
The described bactericidal composition containing Hexanaphthene flusulfamide is used to prevent and treat the disease of crop；Described
Crop includes cereal crops, legume crop, fibre crops, sugar crop, melon crop, water
Orchard crop, dry fruit crop, hobby crop, root crop, oil crops, flowers make
Thing, medicinal crop, crop, green manure pasture crop；Described disease include powdery mildew,
Brown spot, scab, head blight, bakanae disease, rust, moire disease, net blotch, glume blight,
Head smut, banded sclerotial blight, rice blast, peony leaf tip blight, downy mildew, anthracnose, epidemic disease, sore
Scall, damping-off, samping off, rhizome maize ear rot, canker, bacterial wilt, angular leaf spot.
The applying when content of active component depends on being used alone in bactericidal composition of the invention
Consumption, also depends on a kind of mixed ratio of compound with another compound and synergistic effect
Degree, while also relevant with target disease.The weight percent of active component contains in usual composition
Measure is the 1%~90% of gross weight, preferably 5%~80%.According to different preparation types,
Active component content scope is different.Generally, liquid preparation contains by weight 1%~60%
Active material, preferably 5%~50%；Solid pharmaceutical preparation contains by weight 5%~80%
Active material, preferably 10%~80%.
At least contain a kind of surfactant in bactericidal composition of the invention, be beneficial to when applying
Dispersion of the active component in water.Surface-active contents are the 2%~30% of total formulation weight,
Balance of solid or liquid diluent.
Bactericidal composition of the invention can by user using it is preceding through dilute or directly use.
Its preparation can be prepared by processing method known in those skilled in the art, will active component with
Liquid flux or solid carrier mixing after, add surfactant for example dispersant, stabilizer,
One or more in wetting agent, binding agent, antifreeze, disintegrant, defoamer etc..According to
Different dosage forms, can also contain antifreeze known in those skilled in the art etc. in preparation.
Composition is when being made wettable powder comprising following component and content：Active components A
0.5%~80%, active component B 0.5%~60%, dispersant 1%~12%, wetting agent 1%~8%,
Filler surplus.
Composition includes following component and content when being made water dispersible granules：Active components A
0.5%~80%, active component B 0.5%~60%, dispersant 1%~12%, wetting agent 1%~8%,
Disintegrant 1%~10%, binding agent 0~8%, filler surplus.
Composition includes following component and content when being made suspending agent：Active components A
0.5%~50%, active component B 0.5%~50%, dispersant 1%~10%, wetting agent 1%~10%,
Defoamer 0.01%~2%, thickener 0~2%, antifreeze 0~8%, deionized water add to 100%.
Composition includes following component and content when being made aqueous emulsion：Active components A
0.5%~50%, active component B 0.5%~50%, solvent 1%~20%, emulsifying agent 1%~12%,
Antifreeze 0~8%, defoamer 0.01%~2%, thickener 0~2%, deionized water add to 100%.
Composition includes following component and content when being made microemulsion：Active component
A0.5%~50%, active component B 0.5%~50%, emulsifying agent 3%~25%, solvent 1%~10%,
Antifreeze 0~8%, defoamer 0.01%~2%, deionized water add to 100%.
Composition includes following component and content when being made suspension emulsion：Active components A
0.5%~50%, active component B 0.5%~50%, emulsifying agent 1%~10%, dispersant 1%~10%,
Solvent 1%~20%, defoamer 0.01%~2%, thickener 0~2%, antifreeze 0~8%, go
Ionized water adds to 100%.
Composition includes following component and content when being made microcapsule suspending agent：Active component
A0.5%~50%, active component B 0.5%~50%, macromolecule cyst material 1%~10%, point
Powder 2%~10%, solvent 1%~10%, emulsifying agent 1%~7%, pH adjusting agent 0.01%~5%,
Defoamer 0.01%~2%, deionized water adds to 100%.
Composition includes following component and content when being made microcapsule suspension-suspendinagent agent：Active component
A0.5%~50%, active component B 0.5%~50%, macromolecule cyst material 1%~12%, point
Powder 1%~12%, wetting agent 1%~8%, solvent 1%~15%, emulsifying agent 1%~8%, disappear
Infusion 0.01%~2%, thickener 0~2%, pH adjusting agent 0.01%~5%, deionized water add
To 100%.
Wettable powder the key technical indexes of the invention：
Water dispersible granules the key technical indexes of the invention：
Suspending agent the key technical indexes of the invention：
Aqueous emulsion the key technical indexes of the invention：
Microemulsion the key technical indexes of the invention：
Suspension emulsion the key technical indexes of the invention：
Microcapsule suspending agent the key technical indexes of the invention：
Microcapsule suspension-suspendinagent agent the key technical indexes of the invention：
The advantage of the invention is that：
(1) present composition has good synergy and lasting effect within the specific limits, prevents
Effect is higher than single dose；(2) pesticide usage amount is reduced, and reduces residual quantity of the agricultural chemicals on crop, is subtracted
Light environmental pollution；(3) fungicidal spectrum is expanded, to multiple diseases such as powdery mildew, brown spot, black
Star disease, head blight, bakanae disease, rust, moire disease, net blotch, glume blight, head smut,
It is banded sclerotial blight, rice blast, peony leaf tip blight, downy mildew, anthracnose, epidemic disease, shot hole, vertical withered
Disease, samping off, rhizome maize ear rot, canker, bacterial wilt, angular leaf spot have greater activity.
Specific embodiment
With reference to embodiment to further instruction of the present invention, the percentage in embodiment is
Percentage by weight, but the invention is not limited in this.
Application Example one
The wettable powder of embodiment 1~12
Hexanaphthene flusulfamide, active component B, dispersant, wetting agent, filler are mixed, mixed
It is well mixed in conjunction cylinder, is remixed after being crushed through airslide disintegrating mill uniform, you can be made the present invention
Described wettable powder product.Specifically it is shown in Table 1,2.
The each component of 1 embodiment of table 1~6 and content
The each component of 2 embodiment of table 7~12 and content
The water dispersible granules of embodiment 13~24
By Hexanaphthene flusulfamide, active component B, dispersant, wetting agent, disintegrant, filler etc.
The particle diameter for being needed through air-flow crushing together, add binding agent (can add to be not added with) etc. its
Its auxiliary agent, obtains materials of pelletizing.Item is quantitatively sent into fluidized bed granulating dryer by system
Grain and after drying, you can water dispersible granules product of the present invention is obtained, be specifically shown in Table 3,
4。
The each component of 3 embodiment of table 13~18 and content
The each component of 4 embodiment of table 19~24 and content
The suspending agent of embodiment 25~36
By dispersant, wetting agent, defoamer, thickener (can add to be not added with), antifreeze (can
Plus can be not added with), it is well mixed by high speed shear, Hexanaphthene flusulfamide, active component B are added,
Ball milling 2~3 hours in ball mill, make diameter of particle all below 5 μm, and surplus spends
Ionized water is supplied, you can suspending agent product of the present invention is obtained, 5,6 are specifically shown in Table.
The each component of 5 embodiment of table 25~30 and content
The each component of 6 embodiment of table 31~36 and content
The aqueous emulsion of embodiment 37~42
Hexanaphthene flusulfamide, active component B, solvent, emulsifying agent are added together, make to be dissolved into
Homogeneous oil phase；By deionized water, antifreeze (can add to be not added with), (can add can not for thickener
Plus), defoamer mix, into homogeneous water phase.Under high velocity agitation, water is added to
Oil phase, is obtained aqueous emulsion product of the present invention.Specifically it is shown in Table 7.
The each component of 7 embodiment of table 37~42 and content
Triazolone, antibiotic in pyrimidine nucleoside class, 2-cyano-3-amino-3-phenylancryic acetate, bromothalonil in table 1~7 are exchanged,
Novel formulation can be obtained.
The microemulsion of embodiment 43~45
Hexanaphthene flusulfamide, active component B are dissolved in the homogenizer equipped with solvent, by breast
Agent, antifreeze (can add to be not added with), defoamer, it is added to the homogenizing equipped with above-mentioned solution
In device, surplus deionized water mixes and homogenizes strongly after supplying, and finally obtains outward appearance clear
Clear transparent microemulsion product of the present invention.Specifically it is shown in Table 8.
The each component of 8 embodiment of table 43~45 and content
The suspension emulsion of embodiment 46~48
By dispersant, defoamer, thickener (can add to be not added with), (can add can not for antifreeze
Plus) well mixed by high speed shear, add Hexanaphthene flusulfamide, ball milling 2~3 in ball mill
Hour, make diameter of particle all below 5 μm, Hexanaphthene flusulfamide suspending agent is obtained, then
Active component B, emulsifying agent, solvent and various auxiliary agent high speed agitators are directly emulsified outstanding
In floating agent, suspension emulsion product of the present invention is obtained.Specifically it is shown in Table 9.
The each component of 9 embodiment of table 46~48 and content
Active component B refers to triazolone, 2-cyano-3-amino-3-phenylancryic acetate, bromothalonil in table 9.
The microcapsule suspending agent of embodiment 49~51
Hexanaphthene flusulfamide, active component B, macromolecule cyst material, solvent are mixed, is made molten
Solution in a shear condition, oil phase is added to and is adjusted containing emulsifying agent, pH into homogeneous oil phase
In agent, dispersant, the aqueous phase solution of defoamer, surplus is supplied with deionized water, two kinds of materials
Reacted in oil-water interfaces, form high score ascus wall, be made the present composition well dispersed
Microcapsule suspending agent product.Specifically it is shown in Table 10.
The each component of 10 embodiment of table 49~51 and content
The microcapsule suspension-suspendinagent agent of embodiment 52~54
Active component B, macromolecule cyst material, solvent are mixed, make to be dissolved into homogeneous oil phase,
During oil phase is added in a shear condition containing emulsifying agent, the aqueous phase solution of pH adjusting agent,
It is made well dispersed microcapsule suspending agent.By dispersant, wetting agent, defoamer, thickener (can
Plus can be not added with) well mixed by high speed shear, add Hexanaphthene flusulfamide, the ball in ball mill
Mill 2~3 hours, makes diameter of particle all below 5 μm, and suspending agent is obtained, then will be outstanding
Floating agent is added in the aqueous phase solution of micro-capsule suspension, and deionized water supplies surplus, is made this
The well dispersed microcapsule suspension-suspendinagent agent product of inventive composition.Specifically it is shown in Table 11.
The each component of 11 embodiment of table 52~54 and content
Active component B refers to triazolone, 2-cyano-3-amino-3-phenylancryic acetate, bromothalonil in table 11.
The embodiment of the present invention is the method being combined using Toxicity Determination and field test.First
By Toxicity Determination, clear and definite two kinds of medicaments compound by a certain percentage after synergy ratio
(SR), SR ＜ 0.5 are antagonism, and 0.5≤SR≤1.5 are summation action, SR ＞ 1.5
It is synergistic effect, on this basis, then carries out field test.
Test method：After determining the effective inhibition concentration scope of each medicament through prerun, medicament is by effective
Component content sets 5 dosage treatment respectively, if clear water is compareed.Reference《Agricultural chemicals indoor biological is surveyed
Determine test rule bactericide》Carry out, medicament is determined to crop germ using mycelial growth rate method
Virulence.With crossing method measurement colony diameter after 72h, each treatment net growth of calculating,
Mycelial growth inhibition rate.
Net growth (mm)=measurement colony diameter -5
Mycelial growth inhibition rate is converted into probit value (y), liquor strength (μ g/mL) conversion
Into logarithm value (x), virulence regression equation (y=a+bx) is tried to achieve with least square method, and thus
Calculate the EC of every kind of medicament50Value.Two medicament different ratios are calculated according to Wadley methods simultaneously
Synergy ratio (SR), SR ＜ 0.5 are antagonism, and 0.5≤SR≤1.5 are made to be added
With SR ＞ 1.5 are synergistic effect.Computing formula is as follows：
Wherein：A, b are respectively active components A and the shared ratios in combination of active component B；
A is Hexanaphthene flusulfamide；
B is selected from one of triazolone, antibiotic in pyrimidine nucleoside class, 2-cyano-3-amino-3-phenylancryic acetate, bromothalonil and plants.
Application Example two：
For examination disease：Wheat powdery mildew, test medicine is carried by Shaanxi Meibang Pesticide Co., Ltd.
For experimental design：Determine Hexanaphthene flusulfamide and both triazolones different ratio by pilot study
Effective inhibition concentration scope of mixture.
Toxicity test result
The Hexanaphthene flusulfamide of table 12 compounds the toxicity test analysis of results table to wheat powdery mildew with triazolone
As shown in Table 12, Hexanaphthene flusulfamide prevents and treats the proportioning of wheat powdery mildew with triazolone compounding
In 1 60~80 ︰ 1 of ︰, synergy ratio SR is all higher than 1.5, illustrates both in 1 ︰ 60~80
Mixture shows synergistic effect in the range of ︰ 1, and the proportioning of Hexanaphthene flusulfamide and triazolone is 1:
10~20: 1, synergistic effect is more prominent, and synergy ratio is more than 2.30.Through application
People's experiment finds that Hexanaphthene flusulfamide is 20 ︰ 1,15 ︰ 1,10 ︰ 1,9 with the proportioning of triazolone
︰ 1,8 ︰ 1,7 ︰ 1,6 ︰ 1,5 ︰ 1,4 ︰ 1,3 ︰ 1,2 ︰ 1,1 ︰ 1,1 ︰ 2,1
︰ 3,1 ︰ 4,1 ︰ 5,1 ︰ 6,1 ︰ 7,1 ︰ 8,1 ︰ 9, wherein 1 ︰ 10, hexamethylene sulphur bacterium
Amine is 4 with triazolone weight ratio：Synergy ratio is maximum when 1, and synergistic effect is the most obvious.
Application Example three：
For examination disease：Uncinula necator, test medicine is carried by Shaanxi Meibang Pesticide Co., Ltd.
For experimental design：Determine that Hexanaphthene flusulfamide is former with antibiotic in pyrimidine nucleoside class by pilot study
Effective inhibition concentration scope of medicine and the two different ratio mixture
Toxicity test result
The Hexanaphthene flusulfamide of table 13 compounds the toxicity test analysis of results table to uncinula necator with antibiotic in pyrimidine nucleoside class
As shown in Table 13, Hexanaphthene flusulfamide is white with antibiotic in pyrimidine nucleoside class compounding preventing and treating grape
In 1 60~80 ︰ 1 of ︰, synergy ratio SR is all higher than 1.5 to the proportioning of powder disease, illustrates both
Mixture shows synergistic effect, Hexanaphthene flusulfamide and pyrimidine core in the range of the ︰ 1 of 1 ︰ 60~80
, in 1 ︰ 10~20: 1, synergistic effect is more prominent, synergy ratio for the proportioning of glycoside antibiotic
More than 2.25.Hexanaphthene flusulfamide and antibiotic in pyrimidine nucleoside class are found through applicant's experiment
Proportioning for 20 ︰ 1,15 ︰ 1,10 ︰ 1,9 ︰ 1,8 ︰ 1,7 ︰ 1,6 ︰ 1,5 ︰ 1,
4 ︰ 1,3 ︰ 1,2 ︰ 1,1 ︰ 1,1 ︰ 2,1 ︰ 3,1 ︰ 4,1 ︰ 5,1 ︰ 6,1 ︰ 7,
1 ︰ 8,1 ︰ 9,1 ︰ 10, wherein Hexanaphthene flusulfamide are with antibiotic in pyrimidine nucleoside class weight ratio
4：Synergy ratio is maximum when 1, and synergistic effect is the most obvious.
Application Example four：
For examination disease：Wheat scab, test medicine is carried by Shaanxi Meibang Pesticide Co., Ltd.
For experimental design：By pilot study determine Hexanaphthene flusulfamide and 2-cyano-3-amino-3-phenylancryic acetate active compound and the two
Effective inhibition concentration scope of different ratio mixture.
Toxicity test result
The Hexanaphthene flusulfamide of table 14 compounds the toxicity test analysis of results table to wheat scab with 2-cyano-3-amino-3-phenylancryic acetate
As shown in Table 14, Hexanaphthene flusulfamide prevents and treats matching somebody with somebody for wheat scab with 2-cyano-3-amino-3-phenylancryic acetate compounding
Than in 1 60~80 ︰ 1 of ︰, synergy ratio SR is all higher than 1.5, illustrate both in 1 ︰ 60~80
Mixture shows synergistic effect in the range of ︰ 1, and Hexanaphthene flusulfamide exists with the proportioning of 2-cyano-3-amino-3-phenylancryic acetate
1: 20~20: 1, synergistic effect is more prominent, and synergy ratio is more than 2.25.Through Shen
Ask someone experiment find the proportioning of Hexanaphthene flusulfamide and 2-cyano-3-amino-3-phenylancryic acetate be 20 ︰ 1,15 ︰ 1,10 ︰ 1,
9 ︰ 1,8 ︰ 1,7 ︰ 1,6 ︰ 1,5 ︰ 1,4 ︰ 1,3 ︰ 1,2 ︰ 1,1 ︰ 1,1 ︰ 2,
1 ︰ 3,1 ︰ 4,1 ︰ 5,1 ︰ 6,1 ︰ 7,1 ︰ 8,1 ︰ 9,1 ︰ 10,1 ︰ 15,1 ︰
20, wherein Hexanaphthene flusulfamide and 2-cyano-3-amino-3-phenylancryic acetate weight ratio is 1：Synergy ratio is maximum when 1, increases
Effect effect is the most obvious.
Application Example five：
For examination disease：Apple anthracnose, test medicine is carried by Shaanxi Meibang Pesticide Co., Ltd.
For experimental design：By pilot study determine Hexanaphthene flusulfamide and bromothalonil active compound and the two not
With effective inhibition concentration scope of proportioning mixture.
Toxicity test result
The toxicity test analysis of results table of the Hexanaphthene flusulfamide of table 15 and bromothalonil compounded to apple anthracnose
As shown in Table 15, Hexanaphthene flusulfamide prevents and treats the proportioning of apple anthracnose with bromothalonil compounded
In 1 60~80 ︰ 1 of ︰, synergy ratio SR is all higher than 1.5, illustrates both in 1 ︰ 60~80
Mixture shows synergistic effect in the range of ︰ 1, and the proportioning of Hexanaphthene flusulfamide and bromothalonil is 1:
10~20: 1, synergistic effect is more prominent, and synergy ratio is more than 2.20.Through application
People's experiment finds that Hexanaphthene flusulfamide is 20 ︰ 1,15 ︰ 1,10 ︰ 1,9 with the proportioning of bromothalonil
︰ 1,8 ︰ 1,7 ︰ 1,6 ︰ 1,5 ︰ 1,4 ︰ 1,3 ︰ 1,2 ︰ 1,1 ︰ 1,1 ︰ 2,1
︰ 3,1 ︰ 4,1 ︰ 5,1 ︰ 6,1 ︰ 7,1 ︰ 8,1 ︰ 9, wherein 1 ︰ 10, hexamethylene sulphur bacterium
Amine is 2 with bromothalonil weight ratio：Synergy ratio is maximum when 1, and synergistic effect is the most obvious.
Found through experiment：To in various crop after Hexanaphthene flusulfamide and active component B compoundings
Powdery mildew, brown spot, scab, head blight, bakanae disease, rust, moire disease, net blotch,
Glume blight, head smut, banded sclerotial blight, rice blast, peony leaf tip blight, black spot, downy mildew,
Anthracnose, epidemic disease, shot hole, damping-off, samping off, rhizome maize ear rot, canker, green grass or young crops are withered
Disease, the preventing and treating of angular leaf spot have obvious synergistic effect, and synergy ratio is more than 1.5.
Effect experiment part：Test medicine is researched and developed by Shaanxi Meibang Pesticide Co., Ltd., provided, right
According to the Hexanaphthene flusulfamide suspending agent (autogamy) of medicament 20%, 25% trazodone wettable powder (city
Purchase), 4% antibiotic in pyrimidine nucleoside class aqua (purchased in market), 25% 2-cyano-3-amino-3-phenylancryic acetate suspending agent (city
Purchase), 25% bromothalonil microemulsion (purchased in market).
The Hexanaphthene flusulfamide of Application Example six is with active component B and its compounding prevents and treats powdery mildew of cucumber medicine
Effect experiment
This EE investigates the powdery mildew of cucumber state of an illness, in the state of an illness in Shaanxi Province Jingyang County before medicine
First time at initial stage dispenser, every dispenser in 7 days once, is total to dispenser 2 times.7 days after second dispenser,
Disease index is investigated respectively and preventive effect is calculated within 14 days, 30 days.Experimental result is as follows：
The Hexanaphthene flusulfamide of table 16 is with active component B and its compounding prevents and treats the powdery mildew of cucumber test of pesticide effectiveness
As can be seen from Table 16, can be effective after Hexanaphthene flusulfamide and active component B and its compounding
Powdery mildew of cucumber is prevented and treated, while also there is good preventive effect to scab of cucumber, prevention effect is excellent
In the preventive effect of single dose, and preventive effect phase is long.To target crop without bad shadow in experiment scope of medication
Ring.
The Hexanaphthene flusulfamide of Application Example seven is with active component B and its compounding prevents and treats wheat rust drug effect
Experiment
This test arrangement investigates the wheat rust state of an illness, at the beginning of the state of an illness in Shaanxi Province's Weinan City before medicine
First time phase dispenser, every dispenser in 7 days once, is total to dispenser 2 times.3 days after second dispenser,
Disease index is investigated respectively and preventive effect is calculated within 7 days, 15 days.Experimental result is as follows：
The Hexanaphthene flusulfamide of table 17 is with active component B and its compounding prevents and treats the wheat rust test of pesticide effectiveness
As can be seen from Table 17, can be effective after Hexanaphthene flusulfamide and active component B and its compounding
Wheat rust is prevented and treated, while also having very to wheat net blotch, glume blight, powdery mildew, head blight
Good preventive effect, prevention effect is superior to the preventive effect of single dose, and preventive effect phase is long, in experiment medication model
Enclose and interior target crop is had no adverse effects.
The Hexanaphthene flusulfamide of Application Example eight and active component B and its compounding preventing and treating grape grey mould medicine
Effect experiment
This test arrangement investigates the grape grey mould state of an illness, in the state of an illness in Shaanxi Province's Weinan City before medicine
First time at initial stage dispenser, every dispenser in 7 days once, is total to dispenser 2 times.7 days after second dispenser,
Disease index is investigated respectively and preventive effect is calculated within 14 days, 30 days.Experimental result is as follows：
The Hexanaphthene flusulfamide of table 18 and active component B and its compounding preventing and treating grape grey mould test of pesticide effectiveness
As can be seen from Table 18, efficiency is prevented after Hexanaphthene flusulfamide and active component B and its compounding
Grape grey mould is controlled, prevention effect is superior to the preventive effect of single dose, and preventive effect phase is long.Used in experiment
Target crop is had no adverse effects in the range of medicine.
The Hexanaphthene flusulfamide of Application Example nine is with active component B and its compounding prevents and treats rice sheath blight disease medicine
Effect experiment
This test arrangement investigates the rice sheath blight disease state of an illness, in the state of an illness in Shaanxi Province's Hanzhong City before medicine
First time at initial stage dispenser, every dispenser in 7 days once, is total to dispenser 2 times.7 days after second dispenser,
Disease index is investigated respectively and preventive effect is calculated within 14 days, 30 days.Experimental result is as follows：
The Hexanaphthene flusulfamide of table 19 is with active component B and its compounding prevents and treats the rice sheath blight disease test of pesticide effectiveness
As can be seen from Table 19, can be effective after Hexanaphthene flusulfamide and active component B and its compounding
Rice sheath blight disease is prevented and treated, while also there is good preventive effect to rice blast, prevention effect is excellent
In the preventive effect of single dose, and preventive effect phase is long.To target crop without bad shadow in experiment scope of medication
Ring.
The Hexanaphthene flusulfamide of Application Example ten is with active component B and its compounding prevents and treats cercospora brown spot of peanut medicine
Effect experiment
This EE investigates the cercospora brown spot of peanut state of an illness, in the state of an illness in Shaanxi Province's Weinan City before medicine
First time at initial stage dispenser, every dispenser in 7 days once, is total to dispenser 2 times.7 after second dispenser
My god, 14 days, 30 days respectively investigation disease index and calculate preventive effect.Experimental result is as follows：
The Hexanaphthene flusulfamide of table 20 is with active component B and its compounding prevents and treats the cercospora brown spot of peanut test of pesticide effectiveness
As can be seen from Table 20, can be effective after Hexanaphthene flusulfamide and active component B and its compounding
The cercospora brown spot of peanut is prevented and treated, prevention effect is superior to the preventive effect of single dose, and preventive effect phase is long.In experiment
Target crop is had no adverse effects in scope of medication.
Drawn by the experiment of different places throughout the country afterwards, Hexanaphthene flusulfamide and triazolone,
After antibiotic in pyrimidine nucleoside class, 2-cyano-3-amino-3-phenylancryic acetate, bromothalonil compounded to the powdery mildew in various crop,
Brown spot, scab, head blight, bakanae disease, rust, moire disease, net blotch, glume blight,
Head smut, banded sclerotial blight, rice blast, peony leaf tip blight, black spot, downy mildew, anthracnose,
Epidemic disease, shot hole, damping-off, samping off, rhizome maize ear rot, canker, bacterial wilt, angle spot
The preventive effect of the Common Diseases such as disease is 95% so that on excellent, in single dose preventive effect, synergistic effect is obvious.
Claims (5)
1. a kind of bactericidal composition containing Hexanaphthene flusulfamide, it is characterised in that：Effective active composition is active components A and active component B, and active components A is 1: 60~80: 1 with active component B weight ratio, and described active components A is Hexanaphthene flusulfamide, and active component B is 2-cyano-3-amino-3-phenylancryic acetate.
2. the bactericidal composition containing Hexanaphthene flusulfamide according to claim 1, it is characterised in that：Active components A is 1: 40~60: 1 with the weight ratio of active component B.
3. the bactericidal composition containing Hexanaphthene flusulfamide according to claim 2, it is characterised in that：
Hexanaphthene flusulfamide is 1: 20~20: 1 with the weight ratio of 2-cyano-3-amino-3-phenylancryic acetate.
4. the bactericidal composition containing Hexanaphthene flusulfamide according to any one of claims 1 to 3, it is characterised in that：Composition is made wettable powder, water dispersible granules, suspending agent, aqueous emulsion, microemulsion, suspension emulsion, microcapsule suspending agent, microcapsule suspension-suspendinagent agent.
5. the bactericidal composition containing Hexanaphthene flusulfamide according to claim 4 is used to prevent and treat crop powdery mildew, brown spot, scab, head blight, bakanae disease, rust, moire disease, net blotch, glume blight, head smut, banded sclerotial blight, rice blast, peony leaf tip blight, downy mildew, anthracnose, epidemic disease, shot hole, damping-off, samping off, rhizome maize ear rot, canker, bacterial wilt, the purposes of angular leaf spot disease.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510073038.6A CN104686516B (en) | 2012-08-23 | 2012-08-23 | A kind of bactericidal composition containing Hexanaphthene flusulfamide |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210302479.5A CN103621561B (en) | 2012-08-23 | 2012-08-23 | High-efficient bactericidal composition containing hexamethylene flusulfamide |
| CN201510073038.6A CN104686516B (en) | 2012-08-23 | 2012-08-23 | A kind of bactericidal composition containing Hexanaphthene flusulfamide |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210302479.5A Division CN103621561B (en) | 2012-08-23 | 2012-08-23 | High-efficient bactericidal composition containing hexamethylene flusulfamide |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104686516A CN104686516A (en) | 2015-06-10 |
| CN104686516B true CN104686516B (en) | 2017-05-31 |
Family
ID=53334414
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510073038.6A Active CN104686516B (en) | 2012-08-23 | 2012-08-23 | A kind of bactericidal composition containing Hexanaphthene flusulfamide |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104686516B (en) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101595890A (en) * | 2009-05-07 | 2009-12-09 | 深圳诺普信农化股份有限公司 | A kind of 2-cyano-3-amino-3-phenylancryic acetate and triazole type composition and application thereof |
| CN101720764A (en) * | 2008-10-13 | 2010-06-09 | 中国农业大学 | New application of N-(2-trifluoromethyl-4-chlorphenyl)-alpha-oxocyclohexyl sulfamide as sterilizing agent |
| CN101919392A (en) * | 2010-08-31 | 2010-12-22 | 陕西上格之路生物科学有限公司 | Bactericidal composition containing famoxadone and JS399-19 |
-
2012
- 2012-08-23 CN CN201510073038.6A patent/CN104686516B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101720764A (en) * | 2008-10-13 | 2010-06-09 | 中国农业大学 | New application of N-(2-trifluoromethyl-4-chlorphenyl)-alpha-oxocyclohexyl sulfamide as sterilizing agent |
| CN101595890A (en) * | 2009-05-07 | 2009-12-09 | 深圳诺普信农化股份有限公司 | A kind of 2-cyano-3-amino-3-phenylancryic acetate and triazole type composition and application thereof |
| CN101919392A (en) * | 2010-08-31 | 2010-12-22 | 陕西上格之路生物科学有限公司 | Bactericidal composition containing famoxadone and JS399-19 |
Non-Patent Citations (1)
| Title |
|---|
| 创制杀菌剂—环己磺菌胺;张海滨等;《农药》;20120430;第51卷(第4期);287-288 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN104686516A (en) | 2015-06-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103651538B (en) | A kind of bactericidal composition containing zoxamide | |
| CN105145584A (en) | Sterilization composition containing penthiopyrad | |
| CN103583521A (en) | Efficient sterilization composition | |
| CN104285954B (en) | A kind of bactericidal composition | |
| CN104126585A (en) | Compound bactericidal composition containing penflufen | |
| CN103651389A (en) | High-efficiency bactericidal composition containing penthiopyrad and triazole | |
| CN103621562B (en) | A kind of bactericidal composition | |
| CN103704229B (en) | Bactericidal composition containing fluorine azole activated ester | |
| CN104686516B (en) | A kind of bactericidal composition containing Hexanaphthene flusulfamide | |
| CN103621561B (en) | High-efficient bactericidal composition containing hexamethylene flusulfamide | |
| CN104206390B (en) | A kind of bactericidal composition containing triazolone | |
| CN103621527B (en) | Sterilization composition containing cyclohexyl flusulfamide | |
| CN103583536A (en) | Pesticide composition | |
| CN103583562A (en) | An efficient sterilization composition containing hexamethylene flusulfamide | |
| CN103583541B (en) | A kind of bactericidal composition containing Fenarimol | |
| CN103621515B (en) | Chesulfamide-containing pesticide composition | |
| CN105211082A (en) | A kind of composition pesticide containing dimoxystrobin | |
| CN104663660B (en) | A kind of efficient bactericidal composite containing Hexanaphthene flusulfamide | |
| CN104273132B (en) | A kind of efficient bactericidal composite containing Hexanaphthene flusulfamide | |
| CN105580805A (en) | Pesticide composition containing copper (succinate + glutarate + adipate) | |
| CN103931656A (en) | Composition containing brevibacillus laterosporus and triazoles | |
| CN103651371B (en) | High-efficiency bactericidal composition containing zoxamide | |
| CN104137853A (en) | A pesticide composition containing penflufen | |
| CN103583527B (en) | A kind of bactericidal composition containing Fenarimol and triazole type | |
| CN104322501A (en) | Chesulfamide-containing efficient sterilization composition |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| CB03 | Change of inventor or designer information |
Inventor after: Huang Dongmei Inventor before: Zhang Wei |
|
| CB03 | Change of inventor or designer information | ||
| TA01 | Transfer of patent application right | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20170329 Address after: 362609 Yongchun County, Quanzhou City, the town of the town of Peng Peng Mei Village, No. 382 Applicant after: Huang Dongmei Address before: 715500 Weinan City, Shaanxi province Pucheng County agricultural base industrial park Applicant before: Shaanxi Meibang Pesticide Co., Ltd. |
|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20201010 Address after: Room 201, second floor, bingang industrial town, Ganjiang Town, Yuhuan City, Taizhou City, Zhejiang Province Patentee after: Yuhuan Jiyi Incubator Co., Ltd Address before: 362609 Yongchun County, Quanzhou City, the town of the town of Peng Peng Mei Village, No. 382 Patentee before: Huang Dongmei |
|
| TR01 | Transfer of patent right | ||
| EE01 | Entry into force of recordation of patent licensing contract |
Application publication date: 20150610 Assignee: Taizhou like Technology Co., Ltd Assignor: Yuhuan Jiyi Incubator Co., Ltd Contract record no.: X2021330000401 Denomination of invention: Bactericidal composition containing cyclohexylsulfonamide Granted publication date: 20170531 License type: Common License Record date: 20211013 |
|
| EE01 | Entry into force of recordation of patent licensing contract |