CN104645161A - Tendon-relaxation and blood-activation pill for promoting healing of injured bones and preparation method thereof - Google Patents
Tendon-relaxation and blood-activation pill for promoting healing of injured bones and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a tendon-relaxation and blood-activation pill for promoting healing of injured bones. The pill is prepared from the following main raw materials in parts by weight: 10-20 parts of common club moss herbs, 5-15 parts of danshen, 5-15 parts of coloed mistletoe herbs, 15-25 parts of Chinese starjasmine stems, 3-8 parts of rhizoma cibotii, 12-24 parts of cortex periplocae, 20-30 parts of garden balsam stems, 20-40 parts of cortex acanthopanacis, 13-27 parts of rhizoma smilacis glabrae, 4-17 parts of folium artemisiae argyi, 25-35 parts of radix clematidis, 4-10 parts of isopyrum, 20-35 parts of radix angelicae tuhuo, 15-20 parts of dried dragon bones, 10-20 parts of ramulus mori and 10-20 parts of colla corii asini. Blood-activation bone-joining external application paste has an obvious effect in treatment of bone injury, has functions of activating blood and dispelling stasis, relaxing tendons and activating blood, regulating qi blood, and improves the pain caused by bone injures in a long term for patients; and moreover, the pill adopts the medicinal materials which are commonly used in many places, is low in cost, and reduces the economic burden of the patients.
Description
Technical field
The invention discloses a kind of relaxing muscles and tendons to promote blood circulation pill, especially a kind of relaxing muscles and tendons to promote blood circulation pill promoting the injury of the bone to heal and preparation method thereof, the invention belongs to traditional Chinese medicine field.
Background technology
In Traditional Chinese Medicine, bone injury is a more wide in range concept, comprise the diseases such as fracture, joint dislocation, the injury of tendon and muscle, bone injury, periosteum injury, also comprise the diseases such as hyperosteogeny, scapulohumeral periarthritis, cervical spondylosis, prolapse of lumbar intervertebral disc, rheumatic arthritis, to these diseases, the Therapeutic Method of doctor trained in Western medicine is generally oral drugs or is aided with physical therapy, massage etc., and its effect also just controls symptom development, and be difficult to radical cure, and oral western medicine also has certain toxic and side effects.
In the method for existing promotion bone injury healing, Authorization Notice No. CN 101933999 B(application number 200910065367.0) the medicine that patent discloses a kind of set a broken bone, it is characterized in that being prepared from by the raw material of following weight parts: Radix Codonopsis 10-15, Poria 10-15, Fructus Lycii 10-15, Rhizoma Atractylodis Macrocephalae 8-12, Radix Salviae Miltiorrhizae 15-20, Fructus Chaenomelis 8-12, Radix Achyranthis Bidentatae 10-15, Radix Angelicae Sinensis 8-12, Cortex Periplocae 5-10.Authorization Notice No. CN 102526328 B(application number 201210039216.X) the medicine that patent discloses a kind of set a broken bone, it is characterized in that, each raw material is by following weight proportion composition: major ingredient: Radix Angelicae Sinensis 5-10 part, Radix Salviae Miltiorrhizae 10-15 part, Radix Linderae 10-15 part, Caulis Lonicerae 15-30 part, Radix Rehmanniae Preparata 12-15 part, Rhizoma Polygoni Cuspidati 5-10 part, Ramulus Mori 8-10 part, Ramulus Sambuci Williamsii 6-10 part, Folium Artemisiae Argyi 15-20 part, Rhizoma Smilacis Glabrae 11-15 part, Cortex Eucommiae 5-10 part, Radix Dipsaci 5-10 part, Semen Strychni 5-8 part, Ramulus Cinnamomi 9-13 part, Rhizoma Et Radix Notopterygii 10-15 part, Rhizoma Atractylodis 5-10 part, Folium Artemisiae Argyi 15-20 part, Radix Clematidis 15-20 part, Caulis Spatholobi 8-10 part, Cortex Periplocae 10-15 part, Radix Glycyrrhizae 7-10 part, Scorpio 10-15 part, Radix Angelicae Dahuricae 5-10 part, Radix Paeoniae Rubra 8-10 part, Cornu Cervi Pantotrichum 4-8 part, Moschus 3-5 part
Chinese medicine occupies very consequence in promotion bone injury healing as can be seen here, but its main dosage form of existing patent is decoction, for promoting the effect of bone injury healing and not as compositions ideal, can causing extra burden to the health of patient.
Summary of the invention
For the present situation of existing promotion bone injury healing deficiency, an object of the present invention is to provide a kind of relaxing muscles and tendons to promote blood circulation pill promoting the injury of the bone to heal, have easy to carry, action effect is obvious, can be very fast play relaxing muscles and tendons to promote blood circulation blood stasis dispelling, effect that granulation promoting is good for bone, and it adopts Chinese crude drug comparatively common in the localities as raw material, with low cost.
Another object of the present invention is just to provide the preparation method of above-mentioned relaxing muscles and tendons to promote blood circulation pill.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
The relaxing muscles and tendons to promote blood circulation pill promoting the injury of the bone to heal, takes off the primary raw material stating weight proportion and is prepared from: Herba Lycopodii 10-20 part, Radix Salviae Miltiorrhizae 5-15 part, Herba Visci 5-15 part, Caulis Trachelospermi 15-25 part, Rhizoma Cibotii 3-8 part, Cortex Periplocae 12-24 part, Herba speranskiae tuberculatae 20-30 part, Cortex Acanthopancis 20-40 part, Rhizoma Smilacis Glabrae 13-27 part, Folium Artemisiae Argyi 4-17 part, Radix Clematidis 25-35 part, flat fruit 4-10 part, careless Radix Angelicae Pubescentis 20-35 part, Os Draconis 15-20 part, Ramulus Mori 10-20 part, Colla Corii Asini 10-20 part.
The relaxing muscles and tendons to promote blood circulation pill promoting the injury of the bone to heal, optimum ratio, takes off the primary raw material stating weight proportion and is prepared from: Herba Lycopodii 13-18 part, Radix Salviae Miltiorrhizae 8-13 part, Herba Visci 8-13 part, Caulis Trachelospermi 18-23 part, Rhizoma Cibotii 4-6 part, Cortex Periplocae 16-20 part, Herba speranskiae tuberculatae 23-28 part, Cortex Acanthopancis 25-35 part, Rhizoma Smilacis Glabrae 15-25 part, Folium Artemisiae Argyi 7-10 part, Radix Clematidis 28-33 part, flat fruit 6-8 part, careless Radix Angelicae Pubescentis 28-33 part, Os Draconis 16-19 part, Ramulus Mori 13-18 part, Colla Corii Asini 13-18 part.
The relaxing muscles and tendons to promote blood circulation pill promoting the injury of the bone to heal, better preferred proportioning, takes off the primary raw material stating weight proportion and is prepared from: Herba Lycopodii 15 parts, Radix Salviae Miltiorrhizae 10 parts, Herba Visci 10 parts, Caulis Trachelospermi 20 parts, Rhizoma Cibotii 5 parts, Cortex Periplocae 18 parts, Herba speranskiae tuberculatae 25 parts, Cortex Acanthopancis 30 parts, Rhizoma Smilacis Glabrae 20 parts, Folium Artemisiae Argyi 9 parts, Radix Clematidis 30 parts, flat fruit 7 parts, careless Radix Angelicae Pubescentis 30 parts, Os Draconis 17 parts, Ramulus Mori 15 parts, 15 parts, Colla Corii Asini.
The preparation method of above-mentioned relaxing muscles and tendons to promote blood circulation pill, preparation process is as follows:
(1) cleaned by Os Draconis, pinion with iron wire, the outer black inner Huang of big fire bake, turning little baking 20-40 minute, grinds to form smalls, crosses 80-120 mesh sieve stand-by;
(2) be cut into filament by clean to Herba Lycopodii, Radix Salviae Miltiorrhizae and Herba Visci, in dry pot, paving evenly, is slowly sprayed even with white vinegar, and slightly stewing 30-50 minute, big fire quick-fried 2-6 minute, take out the cool smalls that grinds to form that dries in the air stand-by;
(3) by Caulis Trachelospermi, Rhizoma Cibotii, Cortex Periplocae, Herba speranskiae tuberculatae, Cortex Acanthopancis, Rhizoma Smilacis Glabrae, Folium Artemisiae Argyi, Radix Clematidis, flat fruit, grass Radix Angelicae Pubescentis and Ramulus Mori, clean, be placed in shady and cool ventilation place 3-5 days, first food steamer is cleaned with rice vinegar spray even, the Caulis Trachelospermi will handled well again, Rhizoma Cibotii, Cortex Periplocae and Herba speranskiae tuberculatae are layered on food steamer, again even with rice vinegar spray, then by Cortex Acanthopancis, Rhizoma Smilacis Glabrae, Folium Artemisiae Argyi, Radix Clematidis, flat fruit is layered on Caulis Trachelospermi, Rhizoma Cibotii, on Cortex Periplocae and Herba speranskiae tuberculatae, again even with rice vinegar spray, finally careless Radix Angelicae Pubescentis and Ramulus Mori are layered on Cortex Acanthopancis, Rhizoma Smilacis Glabrae, Folium Artemisiae Argyi, Radix Clematidis, on flat fruit, even with rice vinegar spray, steam 20-40 minute, large iron pan is dryouied, the crude drug that rapid input is steamed, parch is flavoursome when sending, cool, it is for subsequent use that common pulverization crosses 80-120 mesh sieve,
(4) be placed in non iron container by Colla Corii Asini, add Colla Corii Asini weight 10-20 warm water doubly, big fire is heated to boiling, until boiling after 3 minutes, add step (1)-(3) gained smalls, obtain mixture, stir after mixture being heated to seethe with excitement and decoct to paste;
(5) getting step (4) gained thick paste is placed in container, and little fire is decocted slowly to 30-40 DEG C, adds Mel, and stir while decoct to thick paste and Mel and merge completely, become wet pill with hand rubbing, little fire dries 20-40 minute slowly, at 60-80 DEG C of dry 3-8 hour, bottle and obtain pill.
Above-mentioned preparation method, the outer black inner Huang of step (1) big fire bake is turning little baking 25-35 minute (preferred, the outer black inner Huang of big fire bake is turning little baking system 30 minutes).
Above-mentioned preparation method, the slightly stewing 35-45 minute of step (2), big fire quick-fried 3-5 minute (preferred, slightly to boil in a covered pot over a slow fire 40 minutes, big fire quick-fried 4 minutes).
Above-mentioned preparation method, step (3) is by Caulis Trachelospermi, Rhizoma Cibotii, Cortex Periplocae, Herba speranskiae tuberculatae, Cortex Acanthopancis, Rhizoma Smilacis Glabrae, Folium Artemisiae Argyi, Radix Clematidis, flat fruit, careless Radix Angelicae Pubescentis and Ramulus Mori, clean, it is (preferred to be placed in shady and cool ventilation place 3.5-4.5 days, by Caulis Trachelospermi, Rhizoma Cibotii, Cortex Periplocae, Herba speranskiae tuberculatae, Cortex Acanthopancis, Rhizoma Smilacis Glabrae, Folium Artemisiae Argyi, Radix Clematidis, flat fruit, careless Radix Angelicae Pubescentis and Ramulus Mori, clean, be placed in shady and cool ventilation place 4 days).
Above-mentioned preparation method, step (3) steams 25-35 minute (preferred, to steam 30 minutes).
Above-mentioned preparation method, step (4) adds Colla Corii Asini weight 13-18 warm water doubly (preferred, to add the warm water of Colla Corii Asini weight 15 times).
Above-mentioned preparation method, step (5) little fire dried 25-35 minute slowly, 65-75 DEG C of dry 4-7 hour (preferred, little fire dried 30 minutes slowly, 70 DEG C of dryings 5.5 hours).
Using method: for making the present invention reach optimum therapeuticing effect, each serving with 3g, takes 3 times, warm water delivery service on 1st, and melt and spread upon bone injury position getting pill 2g warm water before sleep in evening, 1 day once.
This relaxing muscles and tendons to promote blood circulation pill is to the Be very effective of bone injury, and not only relaxing muscles and tendons to promote blood circulation blood stasis dispelling, can also relaxing muscles and tendons relaxing muscles and tendons to promote blood circulation, QI and blood regulating, improves patient for a long time because of the slight illness that bone injury is brought, and the local common medical material of multiselect of the present invention, cheap, alleviate the financial burden of patient.
The relaxing muscles and tendons to promote blood circulation pill promoting the injury of the bone to heal, the pharmacological effect of each crude drug is respectively:
Rhizoma Cibotii: bitter in the mouth, sweet, warm in nature, wind-damp dispelling, invigorating the liver and kidney, strong waist knee joint.For rheumatic arthralgia, soreness of the waist and knees, weakness of the lower extremities.
Herba Visci: bitter in the mouth, the flat wind-damp dispelling of property, invigorating the liver and kidney, bone and muscle strengthening, antiabortive unit.For rheumatic arthralgia, soreness of the waist and knees, muscles and bones is unable, and metrorrhagia is through many, and blood leaking in gestation, frequent fetal movement, has a dizzy spell.
Caulis Trachelospermi: bitter in the mouth, cold nature.There is dispelling wind and removing obstruction in the collateral, effect of removing heat from blood detumescence.For beriberoid pyretic arthralgia, the contracture of muscle arteries and veins, soreness of waist and knee joint, sore throat, injury from falling down
Herba Lycopodii: bitter in the mouth, micro-pungent, warm in nature have expelling wind and removing dampness, and effect of relaxing muscles and tendons and activating QI and blood in the collateral is used for joint aches, joint stuffiness.
Cortex Periplocae: acrid in the mouth, hardship, warm in nature have inducing diuresis to remove edema, wind-damp dispelling, effect of bone and muscle strengthening.Be used for the treatment of edema of lower limbs, shortness of breath and palpitation, anemofrigid-damp arthralgia, soreness of the waist and knees
Herba speranskiae tuberculatae: sweet, acrid, warm, 1. expelling wind and removing dampness, the pungent temperature of these product, Xin Nenghang falls apart, and temperature overcomes the coldness wet.Eight Liver Channel, therefore energy expelling wind and removing dampness, as Compendium of Material Medica is said: Herba speranskiae tuberculatae " controls all rheumatalgia contractures of muscles and bones.If " cause limbs pain because of wind-cold damp pathogen invasion and attack limbs meridians, numb, joint stuffiness.Can select these product, expelling wind and cold victory is wet, and pathogenic factor goes, then all disease spontaneous recovery, 2. relaxing muscles and tendons and activating QI and blood in the collateral, and the pungent loose temperature of these product is led to, and enters Liver Channel, and liver governing tendons. therefore these product have effect of relaxing muscles and tendons and activating QI and blood in the collateral.For the heresy of affection of exogenous wind-cold, lose a surname through gas, disease is seen that limbs muscle arteries and veins shrinks and is taken out urgency, can not relax and turn freely.Can select Herba speranskiae tuberculatae, expelling wind and cold, relaxing muscles and tendons and activating QI and blood in the collateral controls it.As " the sweet peaceful blue or green Chinese herbal medicine choosing in Shan " namely selects these product, control muscles and bones contracture.3. promoting blood circulation and stopping pain, the pungent loose temperature of these product is led to, and enters Liver Channel blood system, therefore can promoting blood circulation and stopping pain.To upper and lower, trusted subordinate's waist knee joint, inside and outside various pain, all can select these product to control it, and get its pungent temperature and be apt to away, the merit of promoting the circulation of QI of invigorating blood circulation, vim and vigour general rule is not bitterly.4 solutions poison rash, the secret red medicine writing paper of spirit " say: " treat pyretic toxicity." " Yang Cheng Empirical formula " select this product, control toxic swelling from the beginning of.
Cortex Acanthopancis: acrid in the mouth, hardship, warm in nature.There is wind-damp dispelling, liver and kidney tonifying, bone and muscle strengthening, the effect of inducing diuresis to remove edema.For Bi condition, muscles and bones flaccidity is soft, children's's walking retardation in children, and body void is weak, edema, beriberi.
Rhizoma Smilacis Glabrae: sweet, light is flat.Removing toxic substances, dehumidifying, easing joint movement.Syphilis and the limbs contracture caused by mercurialism, bones and muscles pain; Damp and hot stranguria with turbid discharge, leukorrhagia, carbuncle, scrofula, scabies.
Folium Artemisiae Argyi: pungent, bitter, temperature.Warming the meridian for stopping bleeding, dispersing cold for relieving pain; External removing dampness to relieve itching.For spitting blood, epistaxis, metrorrhagia, menorrhagia, vaginal bleeding during pregnancy hematochezia, few abdomen cold type of pain, coldness and unbalance in meridians, cold womb is infertile; External treatment skin pruritus.Vinegar Chinese mugwort charcoal warming the meridian for stopping bleeding is hemorrhage for deficient cold type.
Radix Salviae Miltiorrhizae: bitter in the mouth, is slightly cold.Blood circulation promoting and blood stasis dispelling, inducing menstruation to relieve menalgia, clear away heart-fire relieving restlessness, removing heat from blood eliminating carbuncle.For obstruction of qi in the chest and cardialgia, gastral cavity abdomen hypochondriac pain, abdominal mass abdominal mass is gathered, pyretic arthralgia pain, dysphoria and insomnia, menoxenia, and dysmenorrhea amenorrhea, skin infection swells and ache.
Radix Clematidis: acrid in the mouth, salty, warm in nature.There is wind-damp dispelling, the effect of the meridian dredging.For rheumatic arthralgia, numb limbs and tense tendons, the contracture of muscle arteries and veins, joint stuffiness.
Flat fruit: [nature and flavor] skin: bitter in the mouth, puckery; Cool, [function cures mainly] heat-clearing and toxic substances removing; Convergence; Hemostasis.Main laryngopharynx swelling and pain; Spit blood; Dysentery,
Grass Radix Angelicae Pubescentis: [effect] dispersing wind-cold; Invigorating spleen for diuresis; Relaxing muscles and tendons to promote blood circulation; Preventing the attack (or recurrence) of malaria, [nature and flavor] bitter in the mouth; Pungent; Slightly warm in nature, [curing mainly] anemofrigid cold; Cough; Edema due to deficiency of the spleen; Infantile malnutrition; Pain in chest and hypochondrium; Treating swelling and pain by traumatic injury; Rheumatalgia; Lumbago; Fracture; Menoxenia; Traumatic hemorrhage; Malaria,
Os Draconis: [effect] gives birth to product subduing hyperactive YANG to ease mental disorders, for hyperactivity of YANG due to deficiency of YIN, irritable, palpitation and insomnia, has a dizzy spell, demented frightened disease such as grade; Forging rear merit restrains astringent or styptic treatment for spontaneous sweating partially, and be used for premature ejaculation of passing out semen, leukorrhagia metrorrhagia, sweating due to debility chronic diarrhea, eczema prurigo, the open sore part is not held back, traumatic hemorrhage etc.In addition, forge and grind external, energy removing dampness sore, controls again eczema flowing water, with the passing of time unhealed.Os Draconis have the effect of calmness, convergence, astringent or styptic treatment for spontaneous sweating, antidiarrheal
Ramulus Mori: mildly bitter flavor, property is put down.There is wind-damp dispelling, the effect in sharp joint.For Bi condition, shoulder arm, joint aches are numb.
Colla Corii Asini: this product is rectangle block, square block or fourth shape.Pitchy is glossy.Matter is hard and crisp, and section light, fragment is looked in brown translucent illumination.Feeble QI, taste is micro-sweet.To enrich blood YIN nourishing, moisturize, hemostasis.For blood deficiency and yellow complexion, dizzy cardiopalmus, dysphoria and insomnia, xeropulmonary cough.
Relaxing muscles and tendons to promote blood circulation pill of the present invention promotes the principle of bone injury healing based on Chinese medicine.The Chinese medicinal material selected all has relaxing muscles and tendons to promote blood circulation blood stasis dispelling, effect of heat-clearing and toxic substances removing, relaxing muscles and tendons to promote blood circulation blood stasis dispelling, removing obstruction in the collateral to relieve pain, and cheap, and life-time service also can not cause the financial burden of patient, is the medicine promoting that bone injury healing is ideal.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
embodiment 1the relaxing muscles and tendons to promote blood circulation pill promoting the injury of the bone to heal, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): Herba Lycopodii 10 parts, Radix Salviae Miltiorrhizae 5 parts, Herba Visci 5 parts, Caulis Trachelospermi 15 parts, Rhizoma Cibotii 3 parts, Cortex Periplocae 12 parts, Herba speranskiae tuberculatae 20 parts, Cortex Acanthopancis 20 parts, Rhizoma Smilacis Glabrae 13 parts, Folium Artemisiae Argyi 4 parts, Radix Clematidis 25 parts, flat fruit 4 parts, careless Radix Angelicae Pubescentis 20-35 part, Os Draconis 15 parts, Ramulus Mori 10 parts, 10 parts, Colla Corii Asini.
The preparation method of above-mentioned relaxing muscles and tendons to promote blood circulation pill, step is:
(1) cleaned by Os Draconis, pinion with iron wire, the outer black inner Huang of big fire bake, turning little baking system 20 minutes, grinds to form smalls, crosses 80 mesh sieves stand-by;
(2) be cut into filament by clean to Herba Lycopodii, Radix Salviae Miltiorrhizae and Herba Visci, in dry pot, paving evenly, is slowly sprayed even with white vinegar, slightly stewing 30 minutes, and big fire quick-fried 2 minutes, takes out the cool smalls that grinds to form that dries in the air stand-by;
(3) by Caulis Trachelospermi, Rhizoma Cibotii, Cortex Periplocae, Herba speranskiae tuberculatae, Cortex Acanthopancis, Rhizoma Smilacis Glabrae, Folium Artemisiae Argyi, Radix Clematidis, flat fruit, grass Radix Angelicae Pubescentis and Ramulus Mori, clean, be placed in shady and cool ventilation place 3 days, first food steamer is cleaned with rice vinegar spray even, the Caulis Trachelospermi will handled well again, Rhizoma Cibotii, Cortex Periplocae and Herba speranskiae tuberculatae are layered on food steamer, again even with rice vinegar spray, then by Cortex Acanthopancis, Rhizoma Smilacis Glabrae, Folium Artemisiae Argyi, Radix Clematidis, flat fruit is layered on Caulis Trachelospermi, Rhizoma Cibotii, on Cortex Periplocae and Herba speranskiae tuberculatae, again even with rice vinegar spray, finally careless Radix Angelicae Pubescentis and Ramulus Mori are layered on Cortex Acanthopancis, Rhizoma Smilacis Glabrae, Folium Artemisiae Argyi, Radix Clematidis, on flat fruit, even with rice vinegar spray, steam 20 minutes, large iron pan is dryouied, the crude drug that rapid input is steamed, parch is flavoursome when sending, cool, it is for subsequent use that common pulverization crosses 80 mesh sieves,
(4) be placed in non iron container by Colla Corii Asini, add the warm water of Colla Corii Asini weight 10 times, big fire is heated to boiling, until boiling after 3 minutes, add step (1)-(3) gained smalls, obtain mixture, stir after mixture being heated to seethe with excitement and decoct to paste;
(5) getting step (4) gained thick paste is placed in container, and little fire is decocted slowly to 30 DEG C, adds Mel, and stir while decoct to thick paste and Mel and merge completely, become wet pill with hand rubbing, little fire dries 20 minutes slowly, 60 DEG C of dryings 3 hours, bottle and obtain pill.
embodiment 2the relaxing muscles and tendons to promote blood circulation pill promoting the injury of the bone to heal, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): Herba Lycopodii 20 parts, Radix Salviae Miltiorrhizae 15 parts, Herba Visci 15 parts, Caulis Trachelospermi 25 parts, Rhizoma Cibotii 8 parts, Cortex Periplocae 24 parts, Herba speranskiae tuberculatae 30 parts, Cortex Acanthopancis 40 parts, Rhizoma Smilacis Glabrae 27 parts, Folium Artemisiae Argyi 17 parts, Radix Clematidis 35 parts, flat fruit 10 parts, careless Radix Angelicae Pubescentis 35 parts, Os Draconis 20 parts, Ramulus Mori 20 parts, 20 parts, Colla Corii Asini.
The preparation method of above-mentioned relaxing muscles and tendons to promote blood circulation pill, step is:
(1) cleaned by Os Draconis, pinion with iron wire, the outer black inner Huang of big fire bake, turning little baking system 40 minutes, grinds to form smalls, crosses 120 mesh sieves stand-by;
(2) be cut into filament by clean to Herba Lycopodii, Radix Salviae Miltiorrhizae and Herba Visci, in dry pot, paving evenly, is slowly sprayed even with white vinegar, slightly stewing 50 minutes, and big fire quick-fried 6 minutes, takes out the cool smalls that grinds to form that dries in the air stand-by;
(3) by Caulis Trachelospermi, Rhizoma Cibotii, Cortex Periplocae, Herba speranskiae tuberculatae, Cortex Acanthopancis, Rhizoma Smilacis Glabrae, Folium Artemisiae Argyi, Radix Clematidis, flat fruit, grass Radix Angelicae Pubescentis and Ramulus Mori, clean, be placed in shady and cool ventilation place 5 days, first food steamer is cleaned with rice vinegar spray even, the Caulis Trachelospermi will handled well again, Rhizoma Cibotii, Cortex Periplocae and Herba speranskiae tuberculatae are layered on food steamer, again even with rice vinegar spray, then by Cortex Acanthopancis, Rhizoma Smilacis Glabrae, Folium Artemisiae Argyi, Radix Clematidis, flat fruit is layered on Caulis Trachelospermi, Rhizoma Cibotii, on Cortex Periplocae and Herba speranskiae tuberculatae, again even with rice vinegar spray, finally careless Radix Angelicae Pubescentis and Ramulus Mori are layered on Cortex Acanthopancis, Rhizoma Smilacis Glabrae, Folium Artemisiae Argyi, Radix Clematidis, on flat fruit, even with rice vinegar spray, steam 40 minutes, large iron pan is dryouied, the crude drug that rapid input is steamed, parch is flavoursome when sending, cool, it is for subsequent use that common pulverization crosses 120 mesh sieves,
(4) be placed in non iron container by Colla Corii Asini, add the warm water of Colla Corii Asini weight 20 times, big fire is heated to boiling, until boiling after 3 minutes, add step (1)-(3) gained smalls, obtain mixture, stir after mixture being heated to seethe with excitement and decoct to paste;
(5) getting step (4) gained thick paste is placed in container, and little fire is decocted slowly to 40 DEG C, adds Mel, and stir while decoct to thick paste and Mel and merge completely, become wet pill with hand rubbing, little fire dries 40 minutes slowly, 80 DEG C of dryings 8 hours, bottle and obtain pill.
embodiment 3the relaxing muscles and tendons to promote blood circulation pill promoting the injury of the bone to heal, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): Herba Lycopodii 13 parts, Radix Salviae Miltiorrhizae 8 parts, Herba Visci 8 parts, Caulis Trachelospermi 18 parts, Rhizoma Cibotii 4 parts, Cortex Periplocae 16 parts, Herba speranskiae tuberculatae 23 parts, Cortex Acanthopancis 25 parts, Rhizoma Smilacis Glabrae 15 parts, Folium Artemisiae Argyi 7 parts, Radix Clematidis 28 parts, flat fruit 6 parts, careless Radix Angelicae Pubescentis 28 parts, Os Draconis 16 parts, Ramulus Mori 13 parts, 13 parts, Colla Corii Asini.
The preparation method of above-mentioned relaxing muscles and tendons to promote blood circulation pill, step is:
(1) cleaned by Os Draconis, pinion with iron wire, the outer black inner Huang of big fire bake, turning little baking system 25 minutes, grinds to form smalls, crosses 90 mesh sieves stand-by;
(2) be cut into filament by clean to Herba Lycopodii, Radix Salviae Miltiorrhizae and Herba Visci, in dry pot, paving evenly, is slowly sprayed even with white vinegar, slightly stewing 35 minutes, and big fire quick-fried 3 minutes, takes out the cool smalls that grinds to form that dries in the air stand-by;
(3) by Caulis Trachelospermi, Rhizoma Cibotii, Cortex Periplocae, Herba speranskiae tuberculatae, Cortex Acanthopancis, Rhizoma Smilacis Glabrae, Folium Artemisiae Argyi, Radix Clematidis, flat fruit, grass Radix Angelicae Pubescentis and Ramulus Mori, clean, be placed in shady and cool ventilation place 3.5 days, first food steamer is cleaned with rice vinegar spray even, the Caulis Trachelospermi will handled well again, Rhizoma Cibotii, Cortex Periplocae and Herba speranskiae tuberculatae are layered on food steamer, again even with rice vinegar spray, then by Cortex Acanthopancis, Rhizoma Smilacis Glabrae, Folium Artemisiae Argyi, Radix Clematidis, flat fruit is layered on Caulis Trachelospermi, Rhizoma Cibotii, on Cortex Periplocae and Herba speranskiae tuberculatae, again even with rice vinegar spray, finally careless Radix Angelicae Pubescentis and Ramulus Mori are layered on Cortex Acanthopancis, Rhizoma Smilacis Glabrae, Folium Artemisiae Argyi, Radix Clematidis, on flat fruit, even with rice vinegar spray, steam 25 minutes, large iron pan is dryouied, the crude drug that rapid input is steamed, parch is flavoursome when sending, cool, it is for subsequent use that common pulverization crosses 90 mesh sieves,
(4) be placed in non iron container by Colla Corii Asini, add the warm water of Colla Corii Asini weight 13 times, big fire is heated to boiling, until boiling after 3 minutes, add step (1)-(3) gained smalls, obtain mixture, stir after mixture being heated to seethe with excitement and decoct to paste;
(5) getting step (4) gained thick paste is placed in container, and little fire is decocted slowly to 33 DEG C, adds Mel, and stir while decoct to thick paste and Mel and merge completely, become wet pill with hand rubbing, little fire dries 25 minutes slowly, 65 DEG C of dryings 4 hours, bottle and obtain pill.
embodiment 4the relaxing muscles and tendons to promote blood circulation pill promoting the injury of the bone to heal, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): Herba Lycopodii 18 parts, Radix Salviae Miltiorrhizae 13 parts, Herba Visci 13 parts, Caulis Trachelospermi 23 parts, Rhizoma Cibotii 6 parts, Cortex Periplocae 20 parts, Herba speranskiae tuberculatae 28 parts, Cortex Acanthopancis 35 parts, Rhizoma Smilacis Glabrae 25 parts, Folium Artemisiae Argyi 10 parts, Radix Clematidis 33 parts, flat fruit 8 parts, careless Radix Angelicae Pubescentis 33 parts, Os Draconis 19 parts, Ramulus Mori 18 parts, 18 parts, Colla Corii Asini.
The preparation method of above-mentioned relaxing muscles and tendons to promote blood circulation pill, step is:
(1) cleaned by Os Draconis, pinion with iron wire, the outer black inner Huang of big fire bake, turning little baking system 35 minutes, grinds to form smalls, crosses 110 mesh sieves stand-by;
(2) be cut into filament by clean to Herba Lycopodii, Radix Salviae Miltiorrhizae and Herba Visci, in dry pot, paving evenly, is slowly sprayed even with white vinegar, slightly stewing 45 minutes, and big fire quick-fried 5 minutes, takes out the cool smalls that grinds to form that dries in the air stand-by;
(3) by Caulis Trachelospermi, Rhizoma Cibotii, Cortex Periplocae, Herba speranskiae tuberculatae, Cortex Acanthopancis, Rhizoma Smilacis Glabrae, Folium Artemisiae Argyi, Radix Clematidis, flat fruit, grass Radix Angelicae Pubescentis and Ramulus Mori, clean, be placed in shady and cool ventilation place 4.5 days, first food steamer is cleaned with rice vinegar spray even, the Caulis Trachelospermi will handled well again, Rhizoma Cibotii, Cortex Periplocae and Herba speranskiae tuberculatae are layered on food steamer, again even with rice vinegar spray, then by Cortex Acanthopancis, Rhizoma Smilacis Glabrae, Folium Artemisiae Argyi, Radix Clematidis, flat fruit is layered on Caulis Trachelospermi, Rhizoma Cibotii, on Cortex Periplocae and Herba speranskiae tuberculatae, again even with rice vinegar spray, finally careless Radix Angelicae Pubescentis and Ramulus Mori are layered on Cortex Acanthopancis, Rhizoma Smilacis Glabrae, Folium Artemisiae Argyi, Radix Clematidis, on flat fruit, even with rice vinegar spray, steam 35 minutes, large iron pan is dryouied, the crude drug that rapid input is steamed, parch is flavoursome when sending, cool, it is for subsequent use that common pulverization crosses 110 mesh sieves,
(4) be placed in non iron container by Colla Corii Asini, add the warm water of Colla Corii Asini weight 18 times, big fire is heated to boiling, until boiling after 3 minutes, add step (1)-(3) gained smalls, obtain mixture, stir after mixture being heated to seethe with excitement and decoct to paste;
(5) getting step (4) gained thick paste is placed in container, and little fire is decocted slowly to 38 DEG C, adds Mel, and stir while decoct to thick paste and Mel and merge completely, become wet pill with hand rubbing, little fire dries 35 minutes slowly, 75 DEG C of dryings 7 hours, bottle and obtain pill.
embodiment 5the relaxing muscles and tendons to promote blood circulation pill promoting the injury of the bone to heal, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): Herba Lycopodii 15 parts, Radix Salviae Miltiorrhizae 10 parts, Herba Visci 10 parts, Caulis Trachelospermi 20 parts, Rhizoma Cibotii 5 parts, Cortex Periplocae 18 parts, Herba speranskiae tuberculatae 25 parts, Cortex Acanthopancis 30 parts, Rhizoma Smilacis Glabrae 20 parts, Folium Artemisiae Argyi 9 parts, Radix Clematidis 30 parts, flat fruit 7 parts, careless Radix Angelicae Pubescentis 30 parts, Os Draconis 17 parts, Ramulus Mori 15 parts, 15 parts, Colla Corii Asini.
The preparation method of above-mentioned relaxing muscles and tendons to promote blood circulation pill, step is:
(1) cleaned by Os Draconis, pinion with iron wire, the outer black inner Huang of big fire bake, turning little baking system 30 minutes, grinds to form smalls, crosses 100 mesh sieves stand-by;
(2) be cut into filament by clean to Herba Lycopodii, Radix Salviae Miltiorrhizae and Herba Visci, in dry pot, paving evenly, is slowly sprayed even with white vinegar, slightly stewing 40 minutes, and big fire quick-fried 4 minutes, takes out the cool smalls that grinds to form that dries in the air stand-by;
(3) by Caulis Trachelospermi, Rhizoma Cibotii, Cortex Periplocae, Herba speranskiae tuberculatae, Cortex Acanthopancis, Rhizoma Smilacis Glabrae, Folium Artemisiae Argyi, Radix Clematidis, flat fruit, grass Radix Angelicae Pubescentis and Ramulus Mori, clean, be placed in shady and cool ventilation place 4 days, first food steamer is cleaned with rice vinegar spray even, the Caulis Trachelospermi will handled well again, Rhizoma Cibotii, Cortex Periplocae and Herba speranskiae tuberculatae are layered on food steamer, again even with rice vinegar spray, then by Cortex Acanthopancis, Rhizoma Smilacis Glabrae, Folium Artemisiae Argyi, Radix Clematidis, flat fruit is layered on Caulis Trachelospermi, Rhizoma Cibotii, on Cortex Periplocae and Herba speranskiae tuberculatae, again even with rice vinegar spray, finally careless Radix Angelicae Pubescentis and Ramulus Mori are layered on Cortex Acanthopancis, Rhizoma Smilacis Glabrae, Folium Artemisiae Argyi, Radix Clematidis, on flat fruit, even with rice vinegar spray, steam 30 minutes, large iron pan is dryouied, the crude drug that rapid input is steamed, parch is flavoursome when sending, cool, it is for subsequent use that common pulverization crosses 100 mesh sieves,
(4) be placed in non iron container by Colla Corii Asini, add the warm water of Colla Corii Asini weight 15 times, big fire is heated to boiling, until boiling after 3 minutes, add step (1)-(3) gained smalls, obtain mixture, stir after mixture being heated to seethe with excitement and decoct to paste;
(5) getting step (4) gained thick paste is placed in container, and little fire is decocted slowly to 35 DEG C, adds Mel, and stir while decoct to thick paste and Mel and merge completely, become wet pill with hand rubbing, little fire dries 30 minutes slowly, 70 DEG C of dryings 5.5 hours, bottle and obtain pill.
experimental exampleobject is to verify whether this relaxing muscles and tendons to promote blood circulation pill has curative effect to promotion bone injury healing." new Chinese medicine guideline of clinical investigations " according to Ministry of Public Health formulation in 1993 is diagnosis basis, and totally 400 routine patient with bone fracture, the mean age is 50 years old.Random division is administration group and matched group.
Before the experiments one day, record patient health, look over patient body symptom every day, guarantee administration group and matched group situation basically identical.Administration group uses this product embodiments 5 gained relaxing muscles and tendons to promote blood circulation pill every day, within 10 days, is a course for the treatment of.Check patient body situation every day, make a record.Result is as following table 1:
Table 1:
efficacy analysis:when administration group (relaxing muscles and tendons to promote blood circulation pill of the present invention) uses 5 days, most patient sensory symptoms obviously alleviates, obviously feel to take a favorable turn in affected part, patient's emotion takes a turn for the better, during medication 20 days, patient is almost recovered, drug withdrawal a period of time has no repeatedly, the state of an illness is better controlled, matched group take medicine after curative effect obvious.Relaxing muscles and tendons to promote blood circulation pill instant effect of the present invention, can reach the object alleviating rapidly patient's misery, and relapse rate is low, is a kind of relaxing muscles and tendons to promote blood circulation pill promoting bone injury healing safely and effectively.
Claims (10)
1. promote the relaxing muscles and tendons to promote blood circulation pill that the injury of the bone heals, it is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Herba Lycopodii 10-20 part, Radix Salviae Miltiorrhizae 5-15 part, Herba Visci 5-15 part, Caulis Trachelospermi 15-25 part, Rhizoma Cibotii 3-8 part, Cortex Periplocae 12-24 part, Herba speranskiae tuberculatae 20-30 part, Cortex Acanthopancis 20-40 part, Rhizoma Smilacis Glabrae 13-27 part, Folium Artemisiae Argyi 4-17 part, Radix Clematidis 25-35 part, flat fruit 4-10 part, careless Radix Angelicae Pubescentis 20-35 part, Os Draconis 15-20 part, Ramulus Mori 10-20 part, Colla Corii Asini 10-20 part.
2. the relaxing muscles and tendons to promote blood circulation pill of promotion injury of the bone healing according to claim 1, it is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Herba Lycopodii 13-18 part, Radix Salviae Miltiorrhizae 8-13 part, Herba Visci 8-13 part, Caulis Trachelospermi 18-23 part, Rhizoma Cibotii 4-6 part, Cortex Periplocae 16-20 part, Herba speranskiae tuberculatae 23-28 part, Cortex Acanthopancis 25-35 part, Rhizoma Smilacis Glabrae 15-25 part, Folium Artemisiae Argyi 7-10 part, Radix Clematidis 28-33 part, flat fruit 6-8 part, careless Radix Angelicae Pubescentis 28-33 part, Os Draconis 16-19 part, Ramulus Mori 13-18 part, Colla Corii Asini 13-18 part.
3. the relaxing muscles and tendons to promote blood circulation pill of promotion injury of the bone healing according to claim 1, is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Herba Lycopodii 15 parts, Radix Salviae Miltiorrhizae 10 parts, Herba Visci 10 parts, Caulis Trachelospermi 20 parts, Rhizoma Cibotii 5 parts, Cortex Periplocae 18 parts, Herba speranskiae tuberculatae 25 parts, Cortex Acanthopancis 30 parts, Rhizoma Smilacis Glabrae 20 parts, Folium Artemisiae Argyi 9 parts, Radix Clematidis 30 parts, flat fruit 7 parts, careless Radix Angelicae Pubescentis 30 parts, Os Draconis 17 parts, Ramulus Mori 15 parts, 15 parts, Colla Corii Asini.
4. the preparation method of the relaxing muscles and tendons to promote blood circulation pill according to any one of claim 1-3, is characterized in that: step is as follows:
(1) cleaned by Os Draconis, pinion with iron wire, the outer black inner Huang of big fire bake, turning little baking 20-40 minute, grinds to form smalls, crosses 80-120 mesh sieve stand-by;
(2) be cut into filament by clean to Herba Lycopodii, Radix Salviae Miltiorrhizae and Herba Visci, in dry pot, paving evenly, is slowly sprayed even with white vinegar, and slightly stewing 30-50 minute, big fire quick-fried 2-6 minute, take out the cool smalls that grinds to form that dries in the air stand-by;
(3) by Caulis Trachelospermi, Rhizoma Cibotii, Cortex Periplocae, Herba speranskiae tuberculatae, Cortex Acanthopancis, Rhizoma Smilacis Glabrae, Folium Artemisiae Argyi, Radix Clematidis, flat fruit, grass Radix Angelicae Pubescentis and Ramulus Mori, clean, be placed in shady and cool ventilation place 3-5 days, first food steamer is cleaned with rice vinegar spray even, the Caulis Trachelospermi will handled well again, Rhizoma Cibotii, Cortex Periplocae and Herba speranskiae tuberculatae are layered on food steamer, again even with rice vinegar spray, then by Cortex Acanthopancis, Rhizoma Smilacis Glabrae, Folium Artemisiae Argyi, Radix Clematidis, flat fruit is layered on Caulis Trachelospermi, Rhizoma Cibotii, on Cortex Periplocae and Herba speranskiae tuberculatae, again even with rice vinegar spray, finally careless Radix Angelicae Pubescentis and Ramulus Mori are layered on Cortex Acanthopancis, Rhizoma Smilacis Glabrae, Folium Artemisiae Argyi, Radix Clematidis, on flat fruit, even with rice vinegar spray, steam 20-40 minute, large iron pan is dryouied, the crude drug that rapid input is steamed, parch is flavoursome when sending, cool, it is for subsequent use that common pulverization crosses 80-120 mesh sieve,
(4) be placed in non iron container by Colla Corii Asini, add Colla Corii Asini weight 10-20 warm water doubly, big fire is heated to boiling, until boiling after 3 minutes, add step (1)-(3) gained smalls, obtain mixture, stir after mixture being heated to seethe with excitement and decoct to paste;
(5) getting step (4) gained thick paste is placed in container, and little fire is decocted slowly to 30-40 DEG C, adds Mel, and stir while decoct to thick paste and Mel and merge completely, become wet pill with hand rubbing, little fire dries 20-40 minute slowly, at 60-80 DEG C of dry 3-8 hour, bottle and obtain pill.
5. preparation method according to claim 4, is characterized in that: the outer black inner Huang of step (1) big fire bake is turning little baking 25-35 minute (preferred, the outer black inner Huang of big fire bake is turning little baking system 30 minutes).
6. preparation method according to claim 4, is characterized in that: the slightly stewing 35-45 minute of step (2), big fire quick-fried 3-5 minute (preferred, slightly to boil in a covered pot over a slow fire 40 minutes, big fire quick-fried 4 minutes).
7. preparation method according to claim 4, it is characterized in that: step (3) is by Caulis Trachelospermi, Rhizoma Cibotii, Cortex Periplocae, Herba speranskiae tuberculatae, Cortex Acanthopancis, Rhizoma Smilacis Glabrae, Folium Artemisiae Argyi, Radix Clematidis, flat fruit, careless Radix Angelicae Pubescentis and Ramulus Mori, clean, it is (preferred to be placed in shady and cool ventilation place 3.5-4.5 days, by Caulis Trachelospermi, Rhizoma Cibotii, Cortex Periplocae, Herba speranskiae tuberculatae, Cortex Acanthopancis, Rhizoma Smilacis Glabrae, Folium Artemisiae Argyi, Radix Clematidis, flat fruit, careless Radix Angelicae Pubescentis and Ramulus Mori, clean, be placed in shady and cool ventilation place 4 days).
8. preparation method according to claim 4, is characterized in that: step (3) steams 25-35 minute (preferred, to steam 30 minutes).
9. preparation method according to claim 4, is characterized in that: step (4) adds Colla Corii Asini weight 13-18 warm water doubly (preferred, to add the warm water of Colla Corii Asini weight 15 times).
10. preparation method according to claim 4, is characterized in that: step (5) little fire dries 25-35 minute slowly, 65-75 DEG C of dry 4-7 hour (preferred, little fire dried 30 minutes slowly, 70 DEG C of dryings 5.5 hours).
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|---|---|---|---|---|
| CN102058748A (en) * | 2009-11-13 | 2011-05-18 | 上海玉森新药开发有限公司 | Method for preparing muscle relaxing and blood circulation stimulating capsules |
| CN102552616A (en) * | 2010-12-29 | 2012-07-11 | 江西济民可信集团有限公司 | Detection method for tablets capable of relaxing muscles and stimulating blood circulation |
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| CN102058748A (en) * | 2009-11-13 | 2011-05-18 | 上海玉森新药开发有限公司 | Method for preparing muscle relaxing and blood circulation stimulating capsules |
| CN102552616A (en) * | 2010-12-29 | 2012-07-11 | 江西济民可信集团有限公司 | Detection method for tablets capable of relaxing muscles and stimulating blood circulation |
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Application publication date: 20150527 |