CN104644860A - Medicine composition for treating inflammatory external hemorrhoids of pregnant and lying-in women and application thereof - Google Patents
Medicine composition for treating inflammatory external hemorrhoids of pregnant and lying-in women and application thereof Download PDFInfo
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Abstract
The invention discloses a medicine composition for treating inflammatory external hemorrhoids of pregnant and lying-in women. The medicine composition consists of the following components: panax notoginseng, lightyellow sophora root, cortex phellodendri, chrysanthemum flower, peppermint, baikal skullcap root, Chinese rhubarb, dried rehmannia root, pod of Japanese pagodatree, flower of Japanese pagodatree, root-bark of tree peony, processed common monkshood root, Chinese angelica, garden burnet root, all grass of serrulate clearweed, peach seed, root of sinkiang arnebia, yerbadetajo herb, myrrh and elephant hide. Aiming at the characteristics of inflammatory external hemorrhoids of pregnant and lying-in women, and especially because pregnant and lying-in women are not convenient to use western medicines, the medicine composition disclosed by the invention has the targeted effects of relieving pain, relieving itching, stopping bleeding, dredging extravasated blood and removing heat toxicity, ensures that inflammations can be subsided and haemorrhoids can atrophy or even fall off, is significant in curative effect, and cannot cause side effects.
Description
Technical field
The invention belongs to medical art, relate to a kind of Chinese medicine composition, be specifically related to a kind of pharmaceutical composition and application thereof for the treatment of pregnant and lying-in women's inflammatory external hemorrhoid.
Background technology
Anal and bowel pile is commonly called as hemorrhoid, is the distinctive commonly encountered diseases of the mankind, frequently-occurring disease.Show according to relevant reconnaissance information, the sickness rate of anorectal disease is 59.1%, and hemorrhoid account for 87.25% of all anal and intestinal diseases, and wherein common with internal hemorrhoid, account for 52.19% of all anal and intestinal diseases.Men and women all can fall ill, and the sickness rate of women is 67%, and the sickness rate of male is 53.9%, with the sickness rate of women for height; Any age all can fall ill, and wherein the people in 20-40 year is comparatively common, and can increase the weight of gradually along with the increase at age, therefore has saying of " ten people nine hemorrhoid ".
The pathogenic factor of hemorrhoid is a lot of, sitting, for a long time station, tired etc. makes human body be in a kind of fixation postures for a long time, thus affect blood circulation, to make in pelvic cavity internal organs in slow blood flow and abdomen congested, cause haemorrhoidal vein over filling, varicose, protuberance, wall of vein tension force decline and cause hemorrhoid to be one of major reasons of morbidity.If hypomotility, enterokinesia is slowed down, and feces is descending slow or because of habitual constipation, thus compressing vein, make contrafluxion and blood backflow obstacle, cause the intrinsic pressure rising of haemorrhoidal vein, wall of vein resistance reduces, and hemorrhoid sickness rate also can be caused to increase.According to clinical observation and statistics result analysis, there were significant differences for the prevalence in different occupation patient, and the prevalence of government functionary, driver, shop-assistant, teacher is obviously higher clinically.
What blood stasis was positioned at mucosa inside anus is called internal hemorrhoid, and be positioned near inside anal orifice and be called external hemorrhoid, what the two had is called mixed hemorrhoid.The symptom of hemorrhoid is had a pain, has blood in stool in affected part, and time serious, hemorrhoid block can protrude anus outer (prolapsus), just retracts after defecation.Wherein inflammatory thrombosed external hemorrhoid is the one of external hemorrhoid, and it is often because of constipation, cough, overexert or continuing vigorous motion after, konstantinovich's vein breaks, and blood forms oval clot anus edge is subcutaneous, when merging inflammation, anus edge hydroderma, the severe pain of pressing affects minimal invasive treatment and work.The common emergency case of inflammatory external hemorrhoid Shi Zhi section, greatly, there is the complication such as anus edge edema, pain discomfort in the operative treatment length course for the treatment of, misery, explore the Therapeutic Method eliminating or alleviate the symptom such as swelling, pain, it is the target of current clinical research, proved by clinical practice, Chinese medicine, eliminating or alleviate in its symptom produced, has reasonable curative effect.
Summary of the invention
The object of the present invention is to provide a kind of pharmaceutical composition for the treatment of pregnant and lying-in women's inflammatory external hemorrhoid, this pharmaceutical composition is for the feature of pregnant and lying-in women's inflammatory external hemorrhoid, especially pregnant and lying-in women's inconvenience uses the side effect of Western medicine, Western medicine unfavorable to fetus, pain relieving targetedly, antipruritic, hemostasis, desilting blood, relieving heat toxin, inflammatory resolution can be made, blood stasis atrophy even comes off, evident in efficacy, and has no side effect.
Above-mentioned purpose of the present invention is realized by following technical proposals:
Treat a pharmaceutical composition for pregnant and lying-in women's inflammatory external hemorrhoid, the crude drug of described pharmaceutical composition is made up of Radix Notoginseng, Radix Sophorae Flavescentis, Cortex Phellodendri, Flos Chrysanthemi, Herba Menthae, Radix Scutellariae, Radix Et Rhizoma Rhei, Radix Rehmanniae, the Fructus Sophorae, Flos Sophorae, Cortex Moutan, Radix Aconiti Preparata, Radix Angelicae Sinensis, Radix Sanguisorbae, Herba Sarcandrae, Semen Persicae, Radix Arnebiae (Radix Lithospermi), Herba Ecliptae, Myrrha and Corium elephatis.
Further, raw material composition and the parts by weight of making described pharmaceutical composition are: Radix Notoginseng 2-4 part, Radix Sophorae Flavescentis 6-8 part, Cortex Phellodendri 20-30 part, Flos Chrysanthemi 16-25 part, Herba Menthae 4-7 part, Radix Scutellariae 12-18 part, Radix Et Rhizoma Rhei 5-12 part, Radix Rehmanniae 3-5 part, Fructus Sophorae 13-20 part, Flos Sophorae 16-30 part, Cortex Moutan 30-50 part, Radix Aconiti Preparata 15-20 part, Radix Angelicae Sinensis 9-14 part, Radix Sanguisorbae 10-15 part, Herba Sarcandrae 22-30 part, Semen Persicae 7-10 part, Radix Arnebiae (Radix Lithospermi) 4-8 part, Herba Ecliptae 3-6 part, Myrrha 5-12 part, Corium elephatis 5-8 part.
Further, raw material composition and the parts by weight of making described pharmaceutical composition are: Radix Notoginseng 2 parts, Radix Sophorae Flavescentis 8 parts, Cortex Phellodendri 25 parts, Flos Chrysanthemi 20 parts, Herba Menthae 4 parts, Radix Scutellariae 16 parts, Radix Et Rhizoma Rhei 10 parts, Radix Rehmanniae 4 parts, the Fructus Sophorae 20 parts, 28 parts, Flos Sophorae, Cortex Moutan 50 parts, Radix Aconiti Preparata 15 parts, Radix Angelicae Sinensis 14 parts, Radix Sanguisorbae 12 parts, Herba Sarcandrae 25 parts, 7 parts, Semen Persicae, Radix Arnebiae (Radix Lithospermi) 8 parts, Herba Ecliptae 4 parts, Myrrha 10 parts, Corium elephatis 8 parts.
Further, raw material composition and the parts by weight of making described pharmaceutical composition are: Radix Notoginseng 4 parts, Radix Sophorae Flavescentis 8 parts, Cortex Phellodendri 20 parts, Flos Chrysanthemi 18 parts, Herba Menthae 5 parts, Radix Scutellariae 12 parts, Radix Et Rhizoma Rhei 5 parts, Radix Rehmanniae 3.5 parts, the Fructus Sophorae 16 parts, 30 parts, Flos Sophorae, Cortex Moutan 30 parts, Radix Aconiti Preparata 18 parts, Radix Angelicae Sinensis 9 parts, Radix Sanguisorbae 10 parts, Herba Sarcandrae 22 parts, 10 parts, Semen Persicae, Radix Arnebiae (Radix Lithospermi) 4 parts, Herba Ecliptae 6 parts, Myrrha 12 parts, Corium elephatis 5 parts.
Further, raw material composition and the parts by weight of making described pharmaceutical composition are: Radix Notoginseng 3 parts, Radix Sophorae Flavescentis 6 parts, Cortex Phellodendri 20 parts, Flos Chrysanthemi 16 parts, Herba Menthae 7 parts, Radix Scutellariae 18 parts, Radix Et Rhizoma Rhei 6 parts, Radix Rehmanniae 3 parts, the Fructus Sophorae 18 parts, 18 parts, Flos Sophorae, Cortex Moutan 40 parts, Radix Aconiti Preparata 20 parts, Radix Angelicae Sinensis 12 parts, Radix Sanguisorbae 15 parts, Herba Sarcandrae 28 parts, 8 parts, Semen Persicae, Radix Arnebiae (Radix Lithospermi) 5 parts, Herba Ecliptae 3 parts, Myrrha 5 parts, Corium elephatis 3 parts.
Further, raw material composition and the parts by weight of making described pharmaceutical composition are: Radix Notoginseng 2 parts, Radix Sophorae Flavescentis 8 parts, Cortex Phellodendri 30 parts, Flos Chrysanthemi 25 parts, Herba Menthae 6 parts, Radix Scutellariae 13 parts, Radix Et Rhizoma Rhei 12 parts, Radix Rehmanniae 5 parts, the Fructus Sophorae 13 parts, 23 parts, Flos Sophorae, Cortex Moutan 35 parts, Radix Aconiti Preparata 16 parts, Radix Angelicae Sinensis 14 parts, Radix Sanguisorbae 13 parts, Herba Sarcandrae 30 parts, 9 parts, Semen Persicae, Radix Arnebiae (Radix Lithospermi) 6 parts, Herba Ecliptae 6 parts, Myrrha 8 parts, Corium elephatis 7 parts.
Further, raw material composition and the parts by weight of making described pharmaceutical composition are: Radix Notoginseng 4 parts, Radix Sophorae Flavescentis 7 parts, Cortex Phellodendri 28 parts, Flos Chrysanthemi 22 parts, Herba Menthae 4 parts, Radix Scutellariae 15 parts, Radix Et Rhizoma Rhei 5 parts, Radix Rehmanniae 3 parts, the Fructus Sophorae 14 parts, 16 parts, Flos Sophorae, Cortex Moutan 45 parts, Radix Aconiti Preparata 19 parts, Radix Angelicae Sinensis 11 parts, Radix Sanguisorbae 14 parts, Herba Sarcandrae 23 parts, 7 parts, Semen Persicae, Radix Arnebiae (Radix Lithospermi) 7 parts, Herba Ecliptae 6 parts, Myrrha 6 parts, Corium elephatis 8 parts.
Further, described pharmaceutical composition makes external-applied ointment form.
Further, the preparation method of described external-applied ointment comprises the following steps:
(1) take each component by formula proportion in the pharmaceutical composition of described treatment pregnant and lying-in women inflammatory external hemorrhoid, after adding water boil, use little fire instead and boil 30-40 minute, filter, medicinal residues and medicinal liquid are separated;
(2) medicinal residues are added water boil, then boil 30-40 minute with little fire, leach medicinal residues, collect medicinal liquid;
(3) twice medicinal liquid is merged, continue infusion with little fire, be condensed into extractum shape, add appropriate peak honey or glycerol, be modulated into external-applied ointment.
The invention still further relates to the application of described pharmaceutical composition in treatment pregnant and lying-in women inflammatory external hemorrhoid medicine.
The pharmaceutical composition for the treatment of pregnant and lying-in women inflammatory external hemorrhoid provided by the present invention, it for raw material, gives full play to the property of medicine of each component with common Chinese herbal medicine:
Radix Notoginseng: this product is the dry root and rhizome of panax araliaceae plant Panax notoginseng (Burk.) F.H.Chen.Sweet in the mouth, micro-hardship, warm in nature, there is removing stasis to stop bleeding, effects such as analgesic therapy of invigorating blood circulation.For controlling the good merchantable brand of all cards of blood stasis, it is traumatology key medicine.Radix Notoginseng mainly containing Ginsenosides, arasaponin class, Radix Notoginseng propylhomoserin class and Radix Notoginseng polysaccharide class etc., is the active substance that it is main.Radix Notoginseng propylhomoserin has obvious anastalsis, and obviously can increase platelet counts and shorten clotting time; Ginsenoside, arasaponin energy anticoagulant and inhibition thrombosis; Radix Notoginseng total glycosides can immunity moderation, and have significant antiinflammatory action, and have significant maincenter analgesic effect, saponin Rb group has stronger analgesic effect.
Radix Sophorae Flavescentis; Bitter in the mouth; Cold in nature.Return liver, kidney, large intestine, small intestine meridian; Bladder; Heart channel; Urinary bladder channel.Heat clearing and damp drying: extensive use and multiple humidifier fever, as damp-heat dysentery; External can decoct soup washout, for hemorrhoid, and women gynecological.
Cortex Phellodendri: this product is the dry bark of rutaceae wampee Phellodendron chinense Schneid..Bitter in the mouth, cold in nature, energy heat clearing and damp drying, except part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels damp-edema." medication heart method " records Cortex Phellodendri: " control the unbearably painful person of skin ulcer." Cortex Phellodendri contains large number of biological alkali components, has the antibacterial action of wide spectrum, can block nerves joint, nervus centralis is had to the effect of suppression.
Flos Chrysanthemi: sweet; Bitter; Be slightly cold.Function cures mainly, dispelling wind, heat clearing away, improving eyesight, removing toxic substances.Control headache, dizzy, conjunctival congestion, irritable feverish sensation of chest and heart, furuncle, toxic swelling.
Herba Menthae: pungent is cool.Cure mainly, dispelling wind-heat.Refresh oneself, rash.Headache, conjunctival congestion, sore throat, aphtha, rubella, measles, breast side of body feeling of distension and oppression.
Radix Scutellariae: heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive.For hygropyrexia, fever disease in summer vomiting and nausea uncomfortable in chest, damp and hot feeling of fullness, dysentery, jaundice, cough due to lung-heat, high hot excessive thirst, heat in blood tells nosebleed, carbuncle sore tumefacting virus, frequent fetal movement.
Radix Et Rhizoma Rhei: be the root welding technology of polygonum rheum palmatum, Rheum tanguticum or Rheum officinale.Nature and flavor: bitter, cold.Gui Jing: stomach warp; Large intestine channel; Liver Channel; Spleen channel; Effect: attack stagnant; Clearing away damp-heat; Pathogenic fire purging; Removing heat from blood; Blood stasis dispelling; Removing toxic substances.
Radix Rehmanniae: clearing away heat and promoting production of body fluid, removing heat from blood, hemostasis.For consumption of YIN caused by febrile disease, crimson tongue excessive thirst, sends out speckle dermexanthesis, spits blood, epistaxis, laryngopharynx swelling and pain.Radix Rehmanniae clearing away heat and cooling blood, yin nourishing, promotes the production of body fluid.For calentura crimson tongue excessive thirst, yin asthenia generating intrinsic heat, hectic fever due to YIN-deficiency consumptive fever, interior-heat is quenched one's thirst, and sends out speckle dermexanthesis.
The Fructus Sophorae: bitter in the mouth, cold; Enter liver, large intestine channel; There are heat clearing away, removing heat from blood, hemostasia effect, control hemorrhoidal bleeding, erosion of vulva pruritus due to damp pathogen.
Flos Sophorae: cool in nature, bitter in the mouth; Energy heat clearing away, removing heat from blood, hemostasis; Control discharging fresh blood stool, skin sore.
Cortex Moutan: heat clearing away; Promoting blood circulation to remove blood stasis.The main epidemic febrile disease pathogenic heat attacking blood system in febrile diseases, send out speckle, tell nosebleed, the pathogenic bacteria later stage brimful of tears, hot Fu Yin divided heating, deficiency of YIN osteopyrexia and fever, amenorrhea due to stagnation of blood, and dysmenorrhea, carbuncle sore tumefacting virus, falls and flutter the pain of injury, beriberoid pyretic arthralgia.
Radix Aconiti Preparata: pungent, bitter, heat; Poisonous.GUIXIN, liver,kidney,spleen warp.Expelling wind and removing dampness, antalgic.For anemofrigid-damp arthralgia, mastalgia, chest pain with distension sensation, arthralgia, trusted subordinate's cold type of pain, colic of cold type is had a pain, narcotic analgesic.
Radix Angelicae Sinensis: be the dry root of umbelliferae angelica Angelica sinensis (Oliv.) Diels.Meridian distribution of property and flavor is warm in nature, hides sweet, pungent.Return liver, the heart, spleen channel.Function cures mainly: enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.
Radix Sanguisorbae: the plant that Radix Sanguisorbae (formal name used at school: Radix Sanguisorbae) is Rosaceae burnet.Return through liver; Lung; Kidney; Large intestine channel.Effect: cooling blood for hemostasis, heat-clearing and toxic substances removing, detumescence sore.
Herba Sarcandrae: be the Herb of golden chestnut orchid Herba Pileae Scriptae Sarcandra glabra (Thunb.) Nakai, nature and flavor slightly warm in nature, bitter in the mouth, pungent.Function cures mainly: anti-inflammation, dispelling wind and removing obstruction in the collateral, blood circulation promoting and dispersing pathogen accumulation.For pneumonia, appendicitis, cellulitis, rheumatic arthralgia, injury from falling down, tumor.
Semen Persicae has activating blood circulation and dissipating phlegm, the function of loosening bowel to relieve constipation.For amenorrhea, dysmenorrhea, dryness of the intestine constipation etc.Its extract has exudation, and anti-granulation is formed, and the antiinflammatory actions such as penetration enhancement, this product also has anticoagulant, antithrombus formation, the effects such as antiallergic.
Radix Arnebiae (Radix Lithospermi): cold in nature is sweet in the mouth, salty.GUIXIN, Liver Channel.Its function cures mainly: removing heat from blood, invigorates blood circulation, removing toxic substances rash.
Herba Ecliptae: be the herb of dicotyledon medicine feverfew Eclipta prostrata.There is removing heat from blood, hemostasis, the kidney invigorating, effect of tonifying YIN.
Myrrha: have invigorate blood circulation, pain relieving, blood stasis dispelling, detumescence and promoting granulation effect.
Corium elephatis: Gan Xian, temperature.Enter bladder meridian, enter spleen channel.Its function cures mainly: control traumatic hemorrhage, and all wounds.Ulcer does not close up for a long time.
This ointment is made up of Radix Notoginseng, Radix Sophorae Flavescentis, Cortex Phellodendri, Flos Chrysanthemi, Herba Menthae, Radix Scutellariae, Radix Et Rhizoma Rhei, Radix Rehmanniae, the Fructus Sophorae, Flos Sophorae, Cortex Moutan, Radix Aconiti Preparata, Radix Angelicae Sinensis, Radix Sanguisorbae, Herba Sarcandrae, Semen Persicae, Radix Arnebiae (Radix Lithospermi), Herba Ecliptae, Myrrha and Corium elephatis.Radix Notoginseng, Cortex Phellodendri, Radix Scutellariae, Cortex Moutan blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain in side, have obvious analgesia, improve blood circulation and antiphlogistic antibacterial effect, is monarch drug in side; Fructus Sophorae cooling blood for hemostasis, Radix Sophorae Flavescentis heat clearing and damp drying, heat clearing away sophora, removing heat from blood, hemostasis, Radix Et Rhizoma Rhei cooling blood and dissolving stasis, Herba Sarcandrae dispelling wind and removing obstruction in the collateral, blood circulation promoting and dispersing pathogen accumulation, Semen Persicae activating blood circulation and dissipating phlegm, the Fructus Sophorae, Radix Sophorae Flavescentis, Flos Sophorae, Radix Et Rhizoma Rhei, Herba Sarcandrae, Semen Persicae are ministerial drug altogether; Radix Rehmanniae clearing away heat and cooling blood, yin nourishing, to promote the production of body fluid, Radix Arnebiae (Radix Lithospermi), Herba Ecliptae removing heat from blood, to invigorate blood circulation, Chinese angelica blood supplementing is invigorated blood circulation, Myrrha is invigorated blood circulation, pain relieving, blood stasis dispelling, detumescence and promoting granulation, Corium elephatis controls traumatic hemorrhage and all wounds, ulcer does not close up for a long time, Radix Aconiti Preparata expelling wind and removing dampness, pain relieving, Radix Rehmanniae, Radix Arnebiae (Radix Lithospermi), Herba Ecliptae, Radix Angelicae Sinensis, Myrrha, Corium elephatis, Radix Aconiti Preparata are adjuvant drug; There is the Flos Chrysanthemi of antipyretic and antidote functions, Herba Menthae, Radix Sanguisorbae for making medicine.All medicines share the effect of playing heat clearing and damp drying convergence, detumescence, pain relieving, granulation promoting altogether.According to the rule of the traditional Chinese medical science to hemorrhoid, namely the medical knowledge of the body resistance strengthening and constitution consolidating, blood circulation promoting and blood stasis dispelling, removing toxic substances pain relieving hard masses softening and resolving carries out formula, really reaches hemostasis, clear blood stasis, relieving heat toxin, the curative effect of reducing swelling and alleviating pain.
Beneficial effect: traditional Chinese medicine composition for treating successful of the present invention, use Western medicine to the disadvantageous feature of fetus for pregnant and lying-in women, effectively can improve the blood circulation of anus local, not only can pain relieving, antipruritic, hemostasis, desilting blood, relieving heat toxin, and can inflammatory resolution be made, blood stasis atrophy even comes off, unhealthy for diet, that living habit is irregular, the factor such as pregnant and lying-in women's lying on bed for a long time or sitting causes inflammatory external hemorrhoid tool has significant therapeutic effect, and this pharmaceutical composition has no side effect, compare operative treatment, alleviate the misery of patient, economical and practical.
Detailed description of the invention
For making the object of the embodiment of the present invention, technical scheme and advantage clearly, below in conjunction with embodiment, technical scheme of the present invention is clearly and completely described.Obviously, described embodiment is a part of the present invention, instead of whole embodiments.Based on described embodiments of the invention, the every other embodiment that those of ordinary skill in the art obtain under without the need to the prerequisite of creative work, all belongs to the scope of protection of the invention.
Embodiment 1:
A kind of pharmaceutical composition for the treatment of pregnant and lying-in women's inflammatory external hemorrhoid of the present invention, gets following traditional Chinese medicine raw medicine: Radix Notoginseng 2 parts, Radix Sophorae Flavescentis 8 parts, Cortex Phellodendri 25 parts, Flos Chrysanthemi 20 parts, Herba Menthae 4 parts, Radix Scutellariae 16 parts, Radix Et Rhizoma Rhei 10 parts, Radix Rehmanniae 4 parts, the Fructus Sophorae 20 parts, 28 parts, Flos Sophorae, Cortex Moutan 50 parts, Radix Aconiti Preparata 15 parts, Radix Angelicae Sinensis 14 parts, Radix Sanguisorbae 12 parts, Herba Sarcandrae 25 parts, 7 parts, Semen Persicae, Radix Arnebiae (Radix Lithospermi) 8 parts, Herba Ecliptae 4 parts, Myrrha 10 parts, Corium elephatis 8 parts.
Embodiment 2:
A kind of pharmaceutical composition for the treatment of pregnant and lying-in women's inflammatory external hemorrhoid of the present invention, gets following traditional Chinese medicine raw medicine: Radix Notoginseng 4 parts, Radix Sophorae Flavescentis 8 parts, Cortex Phellodendri 20 parts, Flos Chrysanthemi 18 parts, Herba Menthae 5 parts, Radix Scutellariae 12 parts, Radix Et Rhizoma Rhei 5 parts, Radix Rehmanniae 3.5 parts, the Fructus Sophorae 16 parts, 30 parts, Flos Sophorae, Cortex Moutan 30 parts, Radix Aconiti Preparata 18 parts, Radix Angelicae Sinensis 9 parts, Radix Sanguisorbae 10 parts, Herba Sarcandrae 22 parts, 10 parts, Semen Persicae, Radix Arnebiae (Radix Lithospermi) 4 parts, Herba Ecliptae 6 parts, Myrrha 12 parts, Corium elephatis 5 parts.
Embodiment 3:
A kind of pharmaceutical composition for the treatment of pregnant and lying-in women's inflammatory external hemorrhoid of the present invention, gets following traditional Chinese medicine raw medicine: Radix Notoginseng 3 parts, Radix Sophorae Flavescentis 6 parts, Cortex Phellodendri 20 parts, Flos Chrysanthemi 16 parts, Herba Menthae 7 parts, Radix Scutellariae 18 parts, Radix Et Rhizoma Rhei 6 parts, Radix Rehmanniae 3 parts, the Fructus Sophorae 18 parts, 18 parts, Flos Sophorae, Cortex Moutan 40 parts, Radix Aconiti Preparata 20 parts, Radix Angelicae Sinensis 12 parts, Radix Sanguisorbae 15 parts, Herba Sarcandrae 28 parts, 8 parts, Semen Persicae, Radix Arnebiae (Radix Lithospermi) 5 parts, Herba Ecliptae 3 parts, Myrrha 5 parts, Corium elephatis 3 parts.
Embodiment 4:
A kind of pharmaceutical composition for the treatment of pregnant and lying-in women's inflammatory external hemorrhoid of the present invention, gets following traditional Chinese medicine raw medicine: Radix Notoginseng 2 parts, Radix Sophorae Flavescentis 8 parts, Cortex Phellodendri 30 parts, Flos Chrysanthemi 25 parts, Herba Menthae 6 parts, Radix Scutellariae 13 parts, Radix Et Rhizoma Rhei 12 parts, Radix Rehmanniae 5 parts, the Fructus Sophorae 13 parts, 23 parts, Flos Sophorae, Cortex Moutan 35 parts, Radix Aconiti Preparata 16 parts, Radix Angelicae Sinensis 14 parts, Radix Sanguisorbae 13 parts, Herba Sarcandrae 30 parts, 9 parts, Semen Persicae, Radix Arnebiae (Radix Lithospermi) 6 parts, Herba Ecliptae 6 parts, Myrrha 8 parts, Corium elephatis 7 parts.
Embodiment 5:
A kind of pharmaceutical composition for the treatment of pregnant and lying-in women's inflammatory external hemorrhoid of the present invention, gets following traditional Chinese medicine raw medicine: Radix Notoginseng 4 parts, Radix Sophorae Flavescentis 7 parts, Cortex Phellodendri 28 parts, Flos Chrysanthemi 22 parts, Herba Menthae 4 parts, Radix Scutellariae 15 parts, Radix Et Rhizoma Rhei 5 parts, Radix Rehmanniae 3 parts, the Fructus Sophorae 14 parts, 16 parts, Flos Sophorae, Cortex Moutan 45 parts, Radix Aconiti Preparata 19 parts, Radix Angelicae Sinensis 11 parts, Radix Sanguisorbae 14 parts, Herba Sarcandrae 23 parts, 7 parts, Semen Persicae, Radix Arnebiae (Radix Lithospermi) 7 parts, Herba Ecliptae 6 parts, Myrrha 6 parts, Corium elephatis 8 parts.
The pharmaceutical composition of the described treatment pregnant and lying-in women inflammatory external hemorrhoid of embodiment 1-5 can be made into external-applied ointment drug type, wherein:
The preparation method of external-applied ointment comprises the following steps:
(1) take each component by the formula proportion described in embodiment 1-5, after adding water boil, use little fire instead and boil 30-40 minute, filter, medicinal residues and medicinal liquid are separated;
(2) medicinal residues are added water boil, then boil 30-40 minute with little fire, leach medicinal residues, collect medicinal liquid;
(3) twice medicinal liquid is merged, continue infusion with little fire, be condensed into extractum shape, add appropriate peak honey or glycerol, be modulated into external-applied ointment.
Usage and consumption: clean anus after an action of the bowels, then smear this ointment, every day 3-4 time, within one month, is a course for the treatment of, and general 1-3 the course for the treatment of cures.
Clinical trial:
In order to verify the effect of pharmaceutical composition of the present invention, in June ,-2013 in November, 2011, under the guidance of Shandong hospital anorectum department expert, outpatient service place Stochastic choice 120 routine pregnant and lying-in women's inflammatory external hemorrhoid patient, at 23 ~ 33 years old age, all meet " the diagnosis tentative standards of hemorrhoid " of surgery branch of Chinese Medical Association anorectal surgical group formulation in 2000.Be divided into treatment group 60 example and matched group 60 example at random, the aspect there was no significant difference such as age, sex, the course of disease, disease severity of two groups of cases, has comparability (P > 005).
Include case standard in: pregnant and lying-in women, anus is uncomfortable, moist unclean; When there is thrombosis, anus local pain, onset is unexpected.
Excluded cases standard: 1. merge the infull person of the heart, lung, Liver and kidney function; 3. psychotic.
Therapeutic Method:
The external-applied ointment that treatment group selects the pharmaceutical composition of the embodiment of the present invention 3 to make, cleans anus after an action of the bowels during use, then smears this ointment, every day 3-4 time, within one month, is a course for the treatment of, uses 1-3 the course for the treatment of.
Matched group gives MAYINGLONGZHICHUANGGAO, is used in conjunction 1-2 week, and treatments period does not use other relevant medicines.
Observation item comprises: sings and symptoms: pain, external hemorrhoid size;
Statistical procedures: use the process of SPSS1.0 software kit, compares between measurement data two groups and adopts t inspection, compares and adopt X2 inspection between enumeration data two groups.
The standard of curative effect evaluation and result:
Curative effect determinate standard: formulate with reference to hemorrhoid content relevant in " new Chinese medicine guideline of clinical investigations " that Ministry of Public Health is promulgated for 1993.Effective: transference cure, enlargement hemorrhoid block disappears, and anal function is normal; Effective: symptom is improved, and enlargement hemorrhoid block reduces; Nothing: symptom, sign are all without improvement.
Result shows, treatment group total effective rate 98.3%; Matched group total effective rate 53.3%, treatment group total effective rate is obviously better than matched group (P < 0.05), and display hemorrhoid bolt has good therapeutic effect to internal hemorrhoid and mixed hemorrhoid.In table 1.
Table 1 liang group comparitive study
| n | Effective | Effectively | Invalid | Total effective rate (%) | |
| Treatment group | 60 | 53 | 6 | 1 | 98.3 |
| Matched group | 60 | 22 | 10 | 28 | 53.3 |
Note: compared with matched group, P < 0.05
Two groups of cases all do not find obvious adverse reaction.
As can be seen here, medicine of the present invention has instant effect, easy to use, and cure rate is high, the not easily feature such as recurrence.
Here is the sufferer that the daily clinic of inventor contacts and the model case contacted with outpatient service in Shandong hospital anorectum department expert cooperative process:
Case 1:
Zhao, female, 25 years old, in 6 months pregnancy periods, go to a doctor in JIUYUE, 2012, patient suffered from inflammatory external hemorrhoid, uneasy in either sitting or lying, looks into and sees anus place edema, erosion, in purple dark-coloured, touches pain.After clean, smear affected part, every day 2-3 time with the ointment that the formula of embodiment 1 is made, continuous use is after 5 days, swollenly to move back, pain only, then medication 10 days, blood stasis disappearance, follows up a case by regular visits to and has no a recurrence in.
Case 2:
Money, female, 27 years old, people from Lixia District, Jinan City, in 4 months pregnancy periods, time going to a doctor in here, looked into and sees anus proctoptosis, edema, erosion, in purple dark-coloured, touched pain.After an action of the bowels, clean affected part, smears affected part with the ointment that the formula of embodiment 3 is made, every day 3-4 time, and continuous use is after 15 days, swollenly to move back, pain only, then medication 25 days, blood stasis disappearance, follows up a case by regular visits to and has no a recurrence in.
Case 3:
Grandson, female, 32 years old, people from Linzhou City, Zibo, in 6 months pregnancy periods, time medical, each defecation of private prosecution was all very painful, proctoptosis.The ointment adopting the formula of embodiment 4 to make smears affected part, every day 2-3 time, and continuous use is after 5 days, swollenly to move back, pain only, then medication 30 days, blood stasis disappearance, follows up a case by regular visits to and has no a recurrence in.
Last it is noted that above embodiment is only in order to illustrate technical scheme of the present invention, be not intended to limit; Although with reference to previous embodiment to invention has been detailed description, those of ordinary skill in the art is to be understood that: it still can be modified to the technical scheme described in foregoing embodiments, or carries out equivalent replacement to wherein portion of techniques feature; And these amendments or replacement, do not make the essence of appropriate technical solution depart from the scope of various embodiments of the present invention technical scheme.
Claims (10)
1. treat a pharmaceutical composition for pregnant and lying-in women's inflammatory external hemorrhoid, it is characterized in that: the crude drug of described pharmaceutical composition is made up of Radix Notoginseng, Radix Sophorae Flavescentis, Cortex Phellodendri, Flos Chrysanthemi, Herba Menthae, Radix Scutellariae, Radix Et Rhizoma Rhei, Radix Rehmanniae, the Fructus Sophorae, Flos Sophorae, Cortex Moutan, Radix Aconiti Preparata, Radix Angelicae Sinensis, Radix Sanguisorbae, Herba Sarcandrae, Semen Persicae, Radix Arnebiae (Radix Lithospermi), Herba Ecliptae, Myrrha and Corium elephatis.
2. the pharmaceutical composition for the treatment of pregnant and lying-in women inflammatory external hemorrhoid according to claim 1, it is characterized in that: raw material composition and the parts by weight of making described pharmaceutical composition are: Radix Notoginseng 2-4 part, Radix Sophorae Flavescentis 6-8 part, Cortex Phellodendri 20-30 part, Flos Chrysanthemi 16-25 part, Herba Menthae 4-7 part, Radix Scutellariae 12-18 part, Radix Et Rhizoma Rhei 5-12 part, Radix Rehmanniae 3-5 part, Fructus Sophorae 13-20 part, Flos Sophorae 16-30 part, Cortex Moutan 30-50 part, Radix Aconiti Preparata 15-20 part, Radix Angelicae Sinensis 9-14 part, Radix Sanguisorbae 10-15 part, Herba Sarcandrae 22-30 part, Semen Persicae 7-10 part, Radix Arnebiae (Radix Lithospermi) 4-8 part, Herba Ecliptae 3-6 part, Myrrha 5-12 part, Corium elephatis 5-8 part.
3. the pharmaceutical composition for the treatment of pregnant and lying-in women inflammatory external hemorrhoid according to claim 1, is characterized in that: raw material composition and the parts by weight of making described pharmaceutical composition are: Radix Notoginseng 2 parts, Radix Sophorae Flavescentis 8 parts, Cortex Phellodendri 25 parts, Flos Chrysanthemi 20 parts, Herba Menthae 4 parts, Radix Scutellariae 16 parts, Radix Et Rhizoma Rhei 10 parts, Radix Rehmanniae 4 parts, the Fructus Sophorae 20 parts, 28 parts, Flos Sophorae, Cortex Moutan 50 parts, Radix Aconiti Preparata 15 parts, Radix Angelicae Sinensis 14 parts, Radix Sanguisorbae 12 parts, Herba Sarcandrae 25 parts, 7 parts, Semen Persicae, Radix Arnebiae (Radix Lithospermi) 8 parts, Herba Ecliptae 4 parts, Myrrha 10 parts, Corium elephatis 8 parts.
4. the pharmaceutical composition for the treatment of pregnant and lying-in women inflammatory external hemorrhoid according to claim 1, is characterized in that: raw material composition and the parts by weight of making described pharmaceutical composition are: Radix Notoginseng 4 parts, Radix Sophorae Flavescentis 8 parts, Cortex Phellodendri 20 parts, Flos Chrysanthemi 18 parts, Herba Menthae 5 parts, Radix Scutellariae 12 parts, Radix Et Rhizoma Rhei 5 parts, Radix Rehmanniae 3.5 parts, the Fructus Sophorae 16 parts, 30 parts, Flos Sophorae, Cortex Moutan 30 parts, Radix Aconiti Preparata 18 parts, Radix Angelicae Sinensis 9 parts, Radix Sanguisorbae 10 parts, Herba Sarcandrae 22 parts, 10 parts, Semen Persicae, Radix Arnebiae (Radix Lithospermi) 4 parts, Herba Ecliptae 6 parts, Myrrha 12 parts, Corium elephatis 5 parts.
5. the pharmaceutical composition for the treatment of pregnant and lying-in women inflammatory external hemorrhoid according to claim 1, is characterized in that: raw material composition and the parts by weight of making described pharmaceutical composition are: Radix Notoginseng 3 parts, Radix Sophorae Flavescentis 6 parts, Cortex Phellodendri 20 parts, Flos Chrysanthemi 16 parts, Herba Menthae 7 parts, Radix Scutellariae 18 parts, Radix Et Rhizoma Rhei 6 parts, Radix Rehmanniae 3 parts, the Fructus Sophorae 18 parts, 18 parts, Flos Sophorae, Cortex Moutan 40 parts, Radix Aconiti Preparata 20 parts, Radix Angelicae Sinensis 12 parts, Radix Sanguisorbae 15 parts, Herba Sarcandrae 28 parts, 8 parts, Semen Persicae, Radix Arnebiae (Radix Lithospermi) 5 parts, Herba Ecliptae 3 parts, Myrrha 5 parts, Corium elephatis 3 parts.
6. the pharmaceutical composition for the treatment of pregnant and lying-in women inflammatory external hemorrhoid according to claim 1, is characterized in that: raw material composition and the parts by weight of making described pharmaceutical composition are: Radix Notoginseng 2 parts, Radix Sophorae Flavescentis 8 parts, Cortex Phellodendri 30 parts, Flos Chrysanthemi 25 parts, Herba Menthae 6 parts, Radix Scutellariae 13 parts, Radix Et Rhizoma Rhei 12 parts, Radix Rehmanniae 5 parts, the Fructus Sophorae 13 parts, 23 parts, Flos Sophorae, Cortex Moutan 35 parts, Radix Aconiti Preparata 16 parts, Radix Angelicae Sinensis 14 parts, Radix Sanguisorbae 13 parts, Herba Sarcandrae 30 parts, 9 parts, Semen Persicae, Radix Arnebiae (Radix Lithospermi) 6 parts, Herba Ecliptae 6 parts, Myrrha 8 parts, Corium elephatis 7 parts.
7. the pharmaceutical composition for the treatment of pregnant and lying-in women inflammatory external hemorrhoid according to claim 1, is characterized in that: raw material composition and the parts by weight of making described pharmaceutical composition are: Radix Notoginseng 4 parts, Radix Sophorae Flavescentis 7 parts, Cortex Phellodendri 28 parts, Flos Chrysanthemi 22 parts, Herba Menthae 4 parts, Radix Scutellariae 15 parts, Radix Et Rhizoma Rhei 5 parts, Radix Rehmanniae 3 parts, the Fructus Sophorae 14 parts, 16 parts, Flos Sophorae, Cortex Moutan 45 parts, Radix Aconiti Preparata 19 parts, Radix Angelicae Sinensis 11 parts, Radix Sanguisorbae 14 parts, Herba Sarcandrae 23 parts, 7 parts, Semen Persicae, Radix Arnebiae (Radix Lithospermi) 7 parts, Herba Ecliptae 6 parts, Myrrha 6 parts, Corium elephatis 8 parts.
8., according to the pharmaceutical composition of the arbitrary described treatment pregnant and lying-in women inflammatory external hemorrhoid of claim 2-7, it is characterized in that: described pharmaceutical composition makes external-applied ointment form.
9. the pharmaceutical composition for the treatment of pregnant and lying-in women inflammatory external hemorrhoid according to claim 8, it is characterized in that, the preparation method of described external-applied ointment comprises the following steps:
(1) take each component by formula proportion in the pharmaceutical composition of the arbitrary described treatment pregnant and lying-in women inflammatory external hemorrhoid of claim 2-7, after adding water boil, use little fire instead and boil 30-40 minute, filter, medicinal residues and medicinal liquid are separated;
(2) medicinal residues are added water boil, then boil 30-40 minute with little fire, leach medicinal residues, collect medicinal liquid;
(3) twice medicinal liquid is merged, continue infusion with little fire, be condensed into extractum shape, add appropriate peak honey or glycerol, be modulated into external-applied ointment.
10. the application of pharmaceutical composition in treatment pregnant and lying-in women inflammatory external hemorrhoid medicine of the treatment pregnant and lying-in women inflammatory external hemorrhoid as described in as arbitrary in claim 1-9.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510081722.9A CN104644860A (en) | 2015-02-15 | 2015-02-15 | Medicine composition for treating inflammatory external hemorrhoids of pregnant and lying-in women and application thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510081722.9A CN104644860A (en) | 2015-02-15 | 2015-02-15 | Medicine composition for treating inflammatory external hemorrhoids of pregnant and lying-in women and application thereof |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104940762A (en) * | 2015-06-23 | 2015-09-30 | 江琴 | Pharmaceutical composition treating inflammatory external hemorrhoids of pregnant and lying-in women |
| CN105943678A (en) * | 2016-07-11 | 2016-09-21 | 南方医科大学第三附属医院 | Deficiency-reinforcing collateral-dredging patch and preparation method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS604121A (en) * | 1983-06-23 | 1985-01-10 | Taisho Pharmaceut Co Ltd | Suppository |
| CN1258527A (en) * | 1998-12-30 | 2000-07-05 | 苑子毅 | Fast-acting piles-treating Chinese medicine preparation |
-
2015
- 2015-02-15 CN CN201510081722.9A patent/CN104644860A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS604121A (en) * | 1983-06-23 | 1985-01-10 | Taisho Pharmaceut Co Ltd | Suppository |
| CN1258527A (en) * | 1998-12-30 | 2000-07-05 | 苑子毅 | Fast-acting piles-treating Chinese medicine preparation |
Non-Patent Citations (2)
| Title |
|---|
| 秦云峰等: "《中医外治疗法集萃》", 31 October 2002 * |
| 黄卫平: "中药"洗痔汤"治疗肛肠疾病的临床研究", 《中国实验方剂学杂志》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104940762A (en) * | 2015-06-23 | 2015-09-30 | 江琴 | Pharmaceutical composition treating inflammatory external hemorrhoids of pregnant and lying-in women |
| CN105943678A (en) * | 2016-07-11 | 2016-09-21 | 南方医科大学第三附属医院 | Deficiency-reinforcing collateral-dredging patch and preparation method thereof |
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