CN104628771A - 抗病毒药物及其药物组合物 - Google Patents
抗病毒药物及其药物组合物 Download PDFInfo
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- CN104628771A CN104628771A CN201410399934.7A CN201410399934A CN104628771A CN 104628771 A CN104628771 A CN 104628771A CN 201410399934 A CN201410399934 A CN 201410399934A CN 104628771 A CN104628771 A CN 104628771A
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- YTJSFYQNRXLOIC-UHFFFAOYSA-N octadecylsilane Chemical compound CCCCCCCCCCCCCCCCCC[SiH3] YTJSFYQNRXLOIC-UHFFFAOYSA-N 0.000 description 1
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- AKHNMLFCWUSKQB-UHFFFAOYSA-L sodium thiosulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=S AKHNMLFCWUSKQB-UHFFFAOYSA-L 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/60—Quinoline or hydrogenated quinoline ring systems
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/04—Preparation or injection of sample to be analysed
- G01N30/06—Preparation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N2030/022—Column chromatography characterised by the kind of separation mechanism
- G01N2030/027—Liquid chromatography
Landscapes
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
时间(min) | 流动相A(%) | 流动相B(%) |
0 | 80 | 20 |
20 | 20 | 80 |
30 | 20 | 80 |
波数(cm·1) | 归属 |
3231 | N-H |
3063 | 芳族C-H |
2978 | 脂族C-H |
1672 | C-O |
1528 | 酰胺II键 |
1250 | P-O |
1165.1101 | C-N |
976,775 | 芳族 |
极性 | 质量 | 式 | 误差(ppm) | i-Fit | 注释 |
(+ve) | 687.2929 | C32H44N6O9P | 3.2 | 0.4 | (碱+H)+ |
(-ve) | 685.2770 | C32H42N6O9P | 2.8 | 0.2 | (碱+H)- |
Claims (10)
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CN201410399934.7A CN104628771B (zh) | 2014-08-14 | 2014-08-14 | 抗病毒药物及其药物组合物 |
CN201610257085.0A CN105669749B (zh) | 2014-08-14 | 2014-08-14 | 抗病毒药物及组合物 |
CN201610257359.6A CN105884826B (zh) | 2014-08-14 | 2014-08-14 | 抗病毒药物 |
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CN201610257359.6A Division CN105884826B (zh) | 2014-08-14 | 2014-08-14 | 抗病毒药物 |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN113192649A (zh) * | 2021-06-01 | 2021-07-30 | 山东英盛生物技术有限公司 | 一种指导癫痫疾病个体化精准用药的*** |
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CN1100090A (zh) * | 1992-03-11 | 1995-03-15 | 纳赫斯有限公司 | 氧代和羟基取代的烃的胺衍生物 |
CN1135212A (zh) * | 1993-09-10 | 1996-11-06 | 纳赫斯有限公司 | 极性取代的烃类 |
CN1740170A (zh) * | 2004-08-24 | 2006-03-01 | 上海安基生物科技股份有限公司 | 肽类hiv蛋白酶抑制剂的制备方法 |
CN1938017A (zh) * | 2004-01-30 | 2007-03-28 | 辉瑞有限公司 | 治疗组合物 |
WO2009088719A1 (en) * | 2008-01-04 | 2009-07-16 | Gilead Sciences, Inc. | Inhibitors of cytochrome p450 |
-
2014
- 2014-08-14 CN CN201610257359.6A patent/CN105884826B/zh not_active Expired - Fee Related
- 2014-08-14 CN CN201410399934.7A patent/CN104628771B/zh not_active Expired - Fee Related
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
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CN1100090A (zh) * | 1992-03-11 | 1995-03-15 | 纳赫斯有限公司 | 氧代和羟基取代的烃的胺衍生物 |
CN1135212A (zh) * | 1993-09-10 | 1996-11-06 | 纳赫斯有限公司 | 极性取代的烃类 |
CN1938017A (zh) * | 2004-01-30 | 2007-03-28 | 辉瑞有限公司 | 治疗组合物 |
CN1740170A (zh) * | 2004-08-24 | 2006-03-01 | 上海安基生物科技股份有限公司 | 肽类hiv蛋白酶抑制剂的制备方法 |
WO2009088719A1 (en) * | 2008-01-04 | 2009-07-16 | Gilead Sciences, Inc. | Inhibitors of cytochrome p450 |
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Publication number | Priority date | Publication date | Assignee | Title |
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CN113192649A (zh) * | 2021-06-01 | 2021-07-30 | 山东英盛生物技术有限公司 | 一种指导癫痫疾病个体化精准用药的*** |
CN113192649B (zh) * | 2021-06-01 | 2023-09-22 | 山东英盛生物技术有限公司 | 一种指导癫痫疾病个体化精准用药的*** |
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CN105884826B (zh) | 2018-01-19 |
CN105884826A (zh) | 2016-08-24 |
CN104628771B (zh) | 2016-05-11 |
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