CN104623437A - Traditional Chinese medicine composition for treating hydronephrosis and preparation method - Google Patents
Traditional Chinese medicine composition for treating hydronephrosis and preparation method Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition for treating hydronephrosis. The composition is mainly prepared from the following medicinal raw materials in parts by weight: 9-18 parts of pillis ophidiae, 5-12 parts of ciliate desert-grass, 8-10 parts of talc, 9-15 parts of streptocaulon griffithii hook, 9-16 parts of radix aconiti lateralis preparata, 15-30 parts of sealwort, 9-15 parts of seeds of cowherb, 7-12 parts of salvia chinensis, 4-9 parts of curculigo orchioides, 15-30 parts of rhizoma phragmitis, 8-16 parts of humifuse euphorbia herb, 10-20 parts of rhizoma smilacis glabrae, 8-14 parts of sculellaria barbata, 6-10 parts of schizophragma and 10-15 parts of rust-brown crotalaria. The traditional Chinese medicine composition disclosed by the invention can be prepared into various dosages, and is convenient to carry and safe and effective, and can be taken for a long time. The traditional Chinese medicine composition for treating hydronephrosis is developed according to the principle of traditional Chinese medicines and the composition has the functions of clearing away heat and toxic materials, nourishing kidney and inducing diuresis and tonifying spleen and eliminating dampness. The traditional Chinese medicine composition disclosed by the invention is remarkable in curative effect; and through clinical verifications for many years, the curative effect is exact and reliable.
Description
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to and a kind ofly treat hydronephrotic Chinese medicine composition and preparation method.
Background technology
Hydronephrosis is that accumulation, cause urine retention and cause intrarenal pressure to raise, so that renal pelvis renal calices is expanded gradually, the atrophy of excess of the kidney matter and destruction because urine is obstructed from kidney discharge.Hydronephrosis is that the renal pelvis renal calices caused due to ureteral obstruction expands with nephridial tissue atrophy, the pipeline stenosis or occlusion at any position of urinary tract and the disorder of nervimuscular normal function, urine, by there is obstacle, causes urine stream to block, pressure increases gradually because urine is discharged not smooth to block above position, tube chamber expands, and finally causes kidney hydrops, expansion, kidney essential attenuation, renal hypofunction, if bilateral blocks, then there will be uremia, consequence is serious.Hydronephrosis can have two main complication.One is form calculus, and two is cause infection.Infection can increase the weight of the infringement of blocking, accelerating renal function, finally becomes pyonephrosis.Calculus equally also can make to block and infect to increase the weight of, thus promotes mutually, reciprocal causation.Hydronephrosis can also complicated hypertension.Hydronephrotic clinical manifestation has the alternately appearance of lumbago, waist and belly lump, hematuria, oliguria or anuria, oliguria or polyuria, hypertension, spontaneous kidney rupture, heating, abdominal distention stomachache, Nausea and vomiting.Hydronephrosis is often without typical clinical manifestation, and main manifestations is the sings and symptoms of protopathy.Hydronephrosis, dependent disease, belongs to the category that the traditional Chinese medical science " is amassed ", thinks that hydronephrosis is because water wet is not transported, sandstone blocks, deficiency of spleen and stomach, affects water capable, not smooth, the damp and hot bright the moon of disturbance in functioning of QI, water channel.Current for hydronephrotic therapeutic modality mainly based on operation, for lighter hydronephrosis, disease progression slowly, can make regular check on understanding disease progression; Block comparatively light, when pyelocaliectasis is not serious, simple orthomorphia can be done, correct UPJ abnormal, strive for the recovery that renal function is larger; Expand obvious person, then should excise the renal pelvis of pathological changes narrow section and overdistension, remake anastomosis; Renal function destroys very serious, and the normal person of side kidney, can do kidney and cut operation.
Publication number CN 101879288 A(application number 201010216456.3) Chinese patent literature disclose one and treat hydronephrotic Chinese medicinal formulae, with the Radix Astragali, Fructus Lycii, Rhizoma Polygoni Cuspidati, Radix Angelicae Sinensis, Ramulus Cinnamomi, Radix Glycyrrhizae, the Rhizoma Atractylodis Macrocephalae, Folium Pyrrosiae, Herba Houttuyniae, Rhizoma Imperatae, Herba Cirsii, Medulla Tetrapanacis, Flos Caryophylli, Semen Vaccariae and Semen Abutili for raw material is made.Publication number CN 103127356 A(application number 201310054240.5) Chinese patent literature disclose one and treat hydronephrotic Chinese medicine, comprising the Herba Lysimachiae of 25 ~ 35 parts by weight, the Herba Dianthi of 10 ~ 20 parts by weight, the Caulis Akebiae of 5 ~ 15 parts by weight, the Herba Lobeliae Chinensis of 10 ~ 20 parts by weight, the Fructus Broussonetiae of 10 ~ 20 parts by weight, the Rhizoma Dioscoreae of 15 ~ 25 parts by weight, the Radix Glycyrrhizae of 3 ~ 8 parts by weight.Publication number CN 103432513 A(application number 201310307260.9) Chinese patent literature disclose one and treat urinary calculus and hydronephrotic Chinese medicine composition, it is made up of multiple medical material, as 30-50 part Endothelium Corneum Gigeriae Galli, the western Talcum of 35-50 part, 30-60 part Spora Lygodii, 30-50 part Radix Clematidis, 5-10 part Cortex Cinnamomi heart, 10-15 part RADIX CURCUMAE from Sichuan of China, 30-50 part Herba Lysimachiae, 10-15 part river Niu Xi, 15-20 part south reed, 10-20 part Semen Abutili, 10-15 part Semen Plantaginis, 10-15 part Herba Agrimoniae, 6-10 part Clematis kerriana Drumm. Et Craiab, 10-15 part Asteriscus Pseudosciaenae, 15-30 part Radix Salviae Miltiorrhizae, 15-30 part Radix Astragali, 10-15 part RHIZOMA ALISMATIS, 5-10 part sweet state tip, 10-15 part Poria, 6-10 part Radix Linderae, 10-15 part Fructus Psoraleae, 10-20 part Semen Benincasae, 10-20 part Exocarpium Benincasae, 5-15 part Fructus Liquidambaris.
In existing Therapeutic Method, Western medicine can only respite patient ailing, the treatment for this disease can not reach the effect for the treatment of both the principal and secondary aspects of a disease, and the Chinese traditional treatment medicine for this disease is fewer, therefore, strengthens being necessary to the research of this aspect Chinese medicine formula.
Summary of the invention
For the deficiencies in the prior art, the object of this invention is to provide a kind of curative effect safe and reliable, the hydronephrotic Chinese medicine composition for the treatment of of taking convenience and preparation method.
Technical scheme of the present invention is:
One treats hydronephrotic Chinese medicine composition, is prepared from primarily of following bulk drugs, is weight portion: Periostracum Serpentis 9-18, Herba pteridis vittatae 5-12, Talcum 8-10, Radix Streptocauli Griffithii 9-15, Pollen Typhae 10-18, Radix Aconiti Lateralis Preparata 9-16, Rhizoma Polygonati 15-30, Semen Vaccariae 9-15, Herba Salviae Chinensis 7-12, white Rhizoma Curculiginis 4-9, Rhizoma Phragmitis 15-30, Herba Euphorbiae Humifusae 8-16, Rhizoma Smilacis Glabrae 10-20, Herba Scutellariae Barbatae 8-14, Cortex schizophragmatis integrifolii radicis 6-10, Herba Crotalariae Ferrugineae 10-15.
In preferred scheme, Periostracum Serpentis 11-16, Herba pteridis vittatae 7-10, Talcum 8.5-9.5, Radix Streptocauli Griffithii 11-13, Pollen Typhae 12-16, Radix Aconiti Lateralis Preparata 11-14, Rhizoma Polygonati 20-25, Semen Vaccariae 11-13, Herba Salviae Chinensis 9-10, white Rhizoma Curculiginis 5-8, Rhizoma Phragmitis 20-25, Herba Euphorbiae Humifusae 10-14, Rhizoma Smilacis Glabrae 12-18, Herba Scutellariae Barbatae 10-12, Cortex schizophragmatis integrifolii radicis 7-9, Herba Crotalariae Ferrugineae 11-14.
Be more preferably, Periostracum Serpentis 13.5, Herba pteridis vittatae 8.5, Talcum 9, Radix Streptocauli Griffithii 12, Pollen Typhae 14, Radix Aconiti Lateralis Preparata 12.5, Rhizoma Polygonati 22.5, Semen Vaccariae 12, Herba Salviae Chinensis 9.5, white Rhizoma Curculiginis 6.5, Rhizoma Phragmitis 22.5, Herba Euphorbiae Humifusae 12, Rhizoma Smilacis Glabrae 15, Herba Scutellariae Barbatae 11, Cortex schizophragmatis integrifolii radicis 8, Herba Crotalariae Ferrugineae 12.5.
Described a kind of preparation method for the treatment of hydronephrotic Chinese medicine composition decoction is:
(1) get Herba Euphorbiae Humifusae and Herba Scutellariae Barbatae decontamination, be placed in frying pan, intense fire heats, parch surface coke brown, spray liquorice beverage, and go out most Mars, takes out, dry;
(2) Periostracum Serpentis alum water is cleaned, dry, late with rice water leaching one, then be placed in pot, yellow wine spray is even, and low baking temperature is fried to yellow, and taking-up is dried in the air cool;
(3) infiltrated by Rhizoma Polygonati, section, get rice and put in frying pan, moderate heat is heated to a meter smoke, pours Rhizoma Polygonati sheet into, fries when becoming strong yellow to rice, takes out, and sieve removes rice, dries in the air cool;
(4) Radix Aconiti Lateralis Preparata is placed in marmite, decoct with water 40 minutes, then step (1), step (2) and step (3) made medical material and other residue medical materials except Herba Euphorbiae Humifusae, Herba Scutellariae Barbatae, Periostracum Serpentis, Rhizoma Polygonati and Radix Aconiti Lateralis Preparata are put into, wherein Pollen Typhae and Talcum are loaded in penetrating bag, add water and do not have medical material 3cm, after big fire is boiled, be adjusted to little fire boil 40-60 minute (preferred, be adjusted to little fire and boil 45-55 minute; Be more preferably, be adjusted to little fire and boil 50 minutes), Guan Huo, filters, obtains decoction.
Described a kind of preparation method for the treatment of hydronephrotic Chinese medicine composition decoction, the amount of step (3) rice is 0.4 times of quality of medicinal material.
The preparation method of described powder is:
(1) get Herba Euphorbiae Humifusae and Herba Scutellariae Barbatae decontamination, be placed in frying pan, intense fire heats, parch surface coke brown, spray liquorice beverage, and go out most Mars, takes out, dry;
(2) Periostracum Serpentis alum water is cleaned, dry, late with rice water leaching one, then be placed in pot, yellow wine spray is even, and low baking temperature is fried to yellow, and taking-up is dried in the air cool;
(3) infiltrated by Rhizoma Polygonati, section, get rice and put in frying pan, moderate heat is heated to a meter smoke, pours Rhizoma Polygonati sheet into, fries when becoming strong yellow to rice, takes out, and sieve removes rice, dries in the air cool;
(4) Radix Aconiti Lateralis Preparata is placed in marmite, decoct with water 40 minutes, then step (1), step (2) and step (3) made medical material and other residue medical materials except Herba Euphorbiae Humifusae, Herba Scutellariae Barbatae, Periostracum Serpentis, Rhizoma Polygonati and Radix Aconiti Lateralis Preparata are put into, wherein Pollen Typhae and Talcum are loaded in penetrating bag, add water and do not have medical material 3cm, after big fire is boiled, be adjusted to little fire boil 40-60 minute (preferred, be adjusted to little fire and boil 45-55 minute; Be more preferably, be adjusted to little fire and boil 50 minutes), Guan Huo, filters;
(5) step (4) remaining medicinal residues and penetrating bag are added water, decoct 30 minutes, filter, merge twice filtrate, heating is concentrated, and spraying dry, pulverizes and sieves, and obtains powder.
Described a kind of preparation method for the treatment of hydronephrotic Chinese medicine composition composition powders, step (5) was pulverized 80-120 mesh sieve and (preferably, was pulverized 90-110 mesh sieve; Be more preferably, pulverized 100 mesh sieves).
The preparation method of described tablet is:
(1) Periostracum Serpentis alum water is cleaned, dry, late with rice water leaching one, then be placed in pot, yellow wine spray is even, and low baking temperature is fried to yellow, and taking-up is dried in the air cool, pulverizes;
(2) infiltrated by Rhizoma Polygonati, section, get rice and put in frying pan, moderate heat is heated to a meter smoke, pours Rhizoma Polygonati sheet into, fries when becoming strong yellow to rice, takes out, and sieve removes rice, dries in the air cool, pulverizes;
(3) Talcum is removed roguing stone, clean, pound into fragment, be ground into fine powder, water flies, and dries;
(4) other residue medical materials except Periostracum Serpentis, Rhizoma Polygonati and Talcum are picked clean, dry, pulverize respectively, made medicated powder and step (1), step (2) and step (3) made medicated powder are mixed, mixes with pharmaceutical excipients, soft material processed, granulate, dry, granulate, finally be pressed into oval tablet dosage form, obtain tablet.
Described a kind of preparation method for the treatment of hydronephrotic Chinese medicine composition tablet, heavy 0.25-0.35g(is preferred for the every sheet of step (4) made tablet, the heavy 0.3g of the every sheet of tablet).
The preparation method of described pill is:
(1) Periostracum Serpentis alum water is cleaned, dry, late with rice water leaching one, then be placed in pot, yellow wine spray is even, and low baking temperature is fried to yellow, and taking-up is dried in the air cool;
(2) infiltrated by Rhizoma Polygonati, section, get rice and put in frying pan, moderate heat is heated to a meter smoke, pours Rhizoma Polygonati sheet into, fries when becoming strong yellow to rice, takes out, and sieve removes rice, dries in the air cool, pulverizes;
(3) Talcum is removed roguing stone, clean, pound into fragment, be ground into fine powder, water flies, and dries;
(4) other residue medical materials except Periostracum Serpentis, Rhizoma Polygonati and Talcum are picked clean, dry, pulverize together with step (1) made medical material, obtain medicated powder, get 2/3rds of made medicated powder and be placed in penetrating bag, add the soak by water of penetrating bag medicated powder quality 5 times, take out penetrating bag, obtain medicinal liquid;
(5) step (4) made medicine liquid heating is concentrated, mix with step (2) (3) made medicated powder and the medicated powder remaining 1/3rd, dry, pulverize, add refined honey, make pill.
Described a kind of preparation method for the treatment of hydronephrotic Chinese medicine composition pill, step (4) decocts with water 30-50 minute and (preferably, decocts with water 35-45 minute; Be more preferably, decoct with water 40 minutes).
One provided by the invention treats hydronephrotic Chinese medicine composition scientific formula, and preparation is simple, and in addition, excellent results of the present invention also shows:
1, the present invention can be prepared into multiple dosage form, easy to carry, can take for a long time, safe and effective;
2, this prescription develops according to Chinese medicine principle, has heat-clearing and toxic substances removing, supports the effects such as kidney diuretic, the spleen strengthening and damp drying;
3, Chinese medicine composition of the present invention is evident in efficacy, ensures that determined curative effect is reliable through clinical verification for many years.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Periostracum Serpentis: base is former: for Colubridae animal Elaphe taeniurus Cope, rat snake or Zaocys etc. slough off under dry epidermis film.Nature and flavor: salty, sweet are flat.Gui Jing: return Liver Channel.Function cures mainly: dispel the wind, arresting convulsion, removing toxic substances, nebula removing.For infantile convulsion, tic spasm, cataracta, sore throat, furuncle swells, skin pruritus.
Herba pteridis vittatae: base is former: the herb of fern Pteridaceae Pteris plant Herba pteridis vittatae.Nature and flavor: light are flat.Gui Jing: liver; Large intestine; Urinary bladder channel.Function cures mainly: expelling wind and activating blood circulation, removing toxic substances parasite killing.For preventing and treating influenza, dysentery, rheumatalgia, traumatic injury; Centipete bite is controlled in external, scabies.
Talcum: base is former: be silicates mineral talc race Talcum.Nature and flavor: sweet, light, cold.Gui Jing: return bladder, lung, stomach warp.Function cures mainly: inducing diuresis for treating stranguria syndrome, clearing away summer-heat, damp eliminating sore.For pyretic stranguria, stranguria caused by urinary stone, urinates hot puckery pain, heat-damp in summer excessive thirst, damp and hot watery diarrhea; External treatment eczema, eczema, miliaria.
Radix Streptocauli Griffithii: base is former: for asclepiadaceae horse lotus saddle platymiscium horse connects the root of saddle.The property of medicine: sweet, bitter, cool.Function cures mainly: 1, heat-clearing and toxic substances removing.Cure cold heating, and traumatic injury alluvial is swollen and ache, waist and leg ache, chronic nephritis.2, heat-clearing and toxic substances removing, eliminating stasis to stop pain.Control enteritis, dysentery, stomachache, venom.
Pollen Typhae: base is former: be the dry pollen of the turbid Herba Typhae of Typhaceae vegetation water, typha orientalis or congener.Nature and flavor: sweet are flat.Gui Jing: return liver, pericardium channel.Function cures mainly: hemostasis, and blood stasis dispelling is treating stranguria.For spitting blood, epistaxis, spitting of blood, metrorrhagia, traumatic hemorrhage, amenorrhea dysmenorrhea, gastral cavity ventral spine pain, tumbling and swelling, blood strangury and dry pain.
Radix Aconiti Lateralis Preparata: Radix Aconiti Lateralis Preparata: base is former: be the processed goods of ranunculaceae plant Aconitum carmichjaelii Debx. daughter root.Radix Aconiti Lateralis Preparata: get Radix Aconiti Lateralis Preparata and clean, clear water soaks a night, except peeling umbilicus, section, add blister to mouth again and taste slightly numb respectful sense for degree, take out, with ginger decoction leaching 1 ~ 3 day, then cook, roast to seventy percent dry again, pour in pot urgent stir-fry of useing force into and rise to cigarette, micro-drum splits for degree, and taking-up cools.Nature and flavor: pungent, sweet are warm greatly; Poisonous.Gui Jing: GUIXIN, kidney, spleen channel.Function cures mainly: recuperating depleted YANG and rescuing the patient from collapse, mends fire supporing yang, by wind-cold damp pathogen.For YANG-depletion collapse, cold extremities faint pulse, sexual impotence, cold womb, trusted subordinate's cold type of pain, deficiency and coldness is vomited and diarrhoea, YIN-cold edema, yang deficiency diseases caused by exogenous pathogenic factor, arthralgia due to cold-dampnes.
Rhizoma Polygonati: base is former: be the dry rhizome of liliaceous plant P. kingianum, Rhizoma Polygonati or Polygonatum cyrtonema Hua.Nature and flavor: sweet are flat.Gui Jing: return spleen, lung, kidney channel.Function cures mainly: boosting qi and nourishing yin, spleen invigorating, lung moistening, kidney tonifying.For weakness of the spleen and stomach, fatigue and asthenia, xerostomia lack of appetite, deficiency of the lung cough caused by dryness, asthenia of essence and blood, interior-heat is quenched one's thirst.
Semen Vaccariae: base is former: be the dry mature seed of pinkwort Vaccaria segetalis.Nature and flavor: bitter are flat.Gui Jing: return liver, stomach warp.Function cures mainly: promoting blood circulation to restore menstrual flow, and stimulating milk secretion is subsided a swelling.For agalactia, amenorrhea, dysmenorrhea, acute mastitis swells and ache.
Herba Salviae Chinensis: base is former: be the herb of Lamiaceae Salvia platymiscium Herba Salviae Chinensis.Nature and flavor: micro-hardship are flat.Function cures mainly: heat-clearing and toxic substances removing, invigorating blood circulation analgesia.For icterohepatitis, cancer, nephritis, leucorrhea, dysmenorrhea, tuberculous lymphadenitis, elephantiasis; Facial paralysis is controlled in external, mastitis, furuncle and phyma.
White Rhizoma Curculiginis: base is former: be the root of the large Stichopus variegatus (Sempen) of Chuan Xu section plant.Nature and flavor: sweet in the mouth; Micro-hardship; Warm in nature.Function cures mainly: lung benefiting spleen invigorating; By kidney and enhancing body; Relaxing muscles and tendons to promote blood circulation.Main cough due to deficiency of the lung; Insufficiency of the spleen dyspepsia; Impotence due to deficiency of the kidney; Leukorrhagia; Uterine prolapse; Traumatic injury; Fracture.
Rhizoma Phragmitis: base is former: be the fresh of grass phragmites communis or dry rhizome.Nature and flavor: sweet, cold.Gui Jing: attach to the lung and stomach meridians.Function cures mainly: clearing away heat and promoting production of body fluid, relieving restlessness, preventing or arresting vomiting, diuresis.For calentura excessive thirst, gastric heat is vomitted the sound of vomiting, cough due to lung-heat, lung abscess vomiting pus, the puckery pain of pyretic stranguria.
Herba Euphorbiae Humifusae: base is former: be the dry herb of euphorbia plant Radix seu Caulis Parthenocissi tricuspidatae or Herba Euphorbiae supinae.Nature and flavor: pungent are flat.Gui Jing: return liver, large intestine channel.Function cures mainly: heat-clearing and toxic substances removing, cooling blood for hemostasis.For dysentery, have loose bowels, hemoptysis, hematuria, has blood in stool, metrorrhagia, furuncle carbuncle.
Rhizoma Smilacis Glabrae: base is former: be the rhizome of Liliaceae smilax plant smilacis glabra.Composition: rhizome is containing volatile oil: 49 kinds of compositions such as n-hexadecanoic methyl ester; Phenolic acids: 3-0-caffeoyl shikimic acid, ferulic acid; Steroidal saponin, flavonoid glycoside etc.The property of medicine: sweet, light, flat.Return liver,kidney,spleen, stomach warp.Function cures mainly: removing damp-heat, lets out turbid removing toxic substances, easing joint movement.Cure mainly syphilis, stranguria with turbid discharge, have loose bowels, muscles and bones spasm and pain, beriberi, carbuncle, skin ulcer tinea, scrofula, goiter and mercurialism.
Herba Scutellariae Barbatae: base is former: be the dry herb of labiate Herba Scutellariae Barbatae.Nature and flavor: pungent, bitter, cold.Gui Jing: return lung, liver, kidney channel.Function cures mainly: heat-clearing and toxic substances removing, blood stasis dispelling diuresis.For furuncle swelling toxin, laryngopharynx swelling and pain, venom, falls and flutters the pain of injury, edema, jaundice.
Cortex schizophragmatis integrifolii radicis: base is former: be the root bark of saxifragaceae plant Cortex schizophragmatis integrifolii radicis.Nature and flavor: light are cool.Function cures mainly: relaxing muscles and tendons and activating QI and blood in the collateral, expelling wind and activating blood circulation.For bones and muscles pain due to rheumatism, extremities joint is ached.
Herba Crotalariae Ferrugineae: base is former: for the false ground of pulse family Crotalaria plant is blue or the root of bar leaf Herba crotalariae mucronatae or herb.The property of medicine: bitter, micro-acid, flat.Return lung, liver, kidney channel.Function cures mainly: nourishing the liver and kidney, and cough-relieving is breathed heavily, and dampness removing cures mainly tinnitus, deaf, the vertigo, seminal emission, menorrhagia, leucorrhea, chronic cough expectorant blood, asthma, nephritis, dysuria, tonsillitis, parotitis, furuncle swelling toxin.
embodiment 1one treats hydronephrotic Chinese medicine composition, is prepared from primarily of following bulk drugs: Periostracum Serpentis 9g, Herba pteridis vittatae 5g, Talcum 8g, Radix Streptocauli Griffithii 9g, Pollen Typhae 10g, Radix Aconiti Lateralis Preparata 9g, Rhizoma Polygonati 15g, Semen Vaccariae 9g, Herba Salviae Chinensis 7g, white Rhizoma Curculiginis 4g, Rhizoma Phragmitis 15g, Herba Euphorbiae Humifusae 8g, Rhizoma Smilacis Glabrae 10g, Herba Scutellariae Barbatae 8g, Cortex schizophragmatis integrifolii radicis 6g, Herba Crotalariae Ferrugineae 10g.
Above-mentioned a kind of preparation method for the treatment of hydronephrotic Chinese medicine composition decoction is:
(1) get Herba Euphorbiae Humifusae and Herba Scutellariae Barbatae decontamination, be placed in frying pan, intense fire heats, parch surface coke brown, spray liquorice beverage, and go out most Mars, takes out, dry;
(2) Periostracum Serpentis alum water is cleaned, dry, late with rice water leaching one, then be placed in pot, yellow wine spray is even, and low baking temperature is fried to yellow, and taking-up is dried in the air cool;
(3) infiltrated by Rhizoma Polygonati, section, the rice getting quality of medicinal material 0.4 times is put in frying pan, and moderate heat is heated to a meter smoke, pours Rhizoma Polygonati sheet into, fries when becoming strong yellow to rice, takes out, and sieve removes rice, dries in the air cool;
(4) Radix Aconiti Lateralis Preparata is placed in marmite, decoct with water 40 minutes, then step (1), step (2) and step (3) made medical material and other residue medical materials except Herba Euphorbiae Humifusae, Herba Scutellariae Barbatae, Periostracum Serpentis, Rhizoma Polygonati and Radix Aconiti Lateralis Preparata are put into, wherein Pollen Typhae and Talcum are loaded in penetrating bag, add water and do not have medical material 3cm, after big fire is boiled, be adjusted to little fire and boil 50 minutes, Guan Huo, filters, obtains decoction.
embodiment 2one treats hydronephrotic Chinese medicine composition, is prepared from primarily of following bulk drugs: Periostracum Serpentis 18g, Herba pteridis vittatae 12g, Talcum 10g, Radix Streptocauli Griffithii 15g, Pollen Typhae 18g, Radix Aconiti Lateralis Preparata 16g, Rhizoma Polygonati 30g, Semen Vaccariae 15g, Herba Salviae Chinensis 12g, white Rhizoma Curculiginis 9g, Rhizoma Phragmitis 30g, Herba Euphorbiae Humifusae 16g, Rhizoma Smilacis Glabrae 20g, Herba Scutellariae Barbatae 14g, Cortex schizophragmatis integrifolii radicis 10g, Herba Crotalariae Ferrugineae 15g.
A kind of preparation method for the treatment of hydronephrotic Chinese medicine composition composition powders is:
(1) get Herba Euphorbiae Humifusae and Herba Scutellariae Barbatae decontamination, be placed in frying pan, intense fire heats, parch surface coke brown, spray liquorice beverage, and go out most Mars, takes out, dry;
(2) Periostracum Serpentis alum water is cleaned, dry, late with rice water leaching one, then be placed in pot, yellow wine spray is even, and low baking temperature is fried to yellow, and taking-up is dried in the air cool;
(3) infiltrated by Rhizoma Polygonati, section, get rice and put in frying pan, moderate heat is heated to a meter smoke, pours Rhizoma Polygonati sheet into, fries when becoming strong yellow to rice, takes out, and sieve removes rice, dries in the air cool;
(4) Radix Aconiti Lateralis Preparata is placed in marmite, decoct with water 40 minutes, then step (1), step (2) and step (3) made medical material and other residue medical materials except Herba Euphorbiae Humifusae, Herba Scutellariae Barbatae, Periostracum Serpentis, Rhizoma Polygonati and Radix Aconiti Lateralis Preparata are put into, wherein Pollen Typhae and Talcum are loaded in penetrating bag, add water and do not have medical material 3cm, after big fire is boiled, be adjusted to little fire and boil 50 minutes, Guan Huo, filters;
(5) step (4) remaining medicinal residues and penetrating bag are added water, decoct 30 minutes, filter, merge twice filtrate, heating is concentrated, and spraying dry, pulverized 100 mesh sieves, and obtained powder.
Model case: xxx, female, 39 years old.Main suit: nearly one month, sensation waist is ached, and lower limb have edema phenomenon, oliguria and yellow, nocturnal pollakiuria, after occur that paroxysmal renal colic is then medical, during inspection, You Shen district knocking pain, pale tongue, deep-slow pulse, ultrasound diagnosis display minor renal calices has slight expansion, and renal pyramids top flattens, and is diagnosed as mild hydronephrotic kidney.
Take the present embodiment gained one and treat hydronephrotic Chinese medicine composition composition powders, each one bag of about 3-5g, every day 3 times, warm boiled water, 30 days courses for the treatment of.After taking a course for the treatment of, malaise symptoms alleviates, and edema disappears, and after continuing to take two courses for the treatment of, malaise symptoms disappears, and patient's self-induction condition is good, and hospital checks, and hydronephrosis disappears, and kidney is normal, and patient fully recovers.
embodiment 3one treats hydronephrotic Chinese medicine composition, is prepared from primarily of following bulk drugs: Periostracum Serpentis 11g, Herba pteridis vittatae 7g, Talcum 8.5g, Radix Streptocauli Griffithii 11g, Pollen Typhae 12g, Radix Aconiti Lateralis Preparata 11g, Rhizoma Polygonati 20g, Semen Vaccariae 11g, Herba Salviae Chinensis 9g, white Rhizoma Curculiginis 5g, Rhizoma Phragmitis 20g, Herba Euphorbiae Humifusae 10g, Rhizoma Smilacis Glabrae 12g, Herba Scutellariae Barbatae 10g, Cortex schizophragmatis integrifolii radicis 7g, Herba Crotalariae Ferrugineae 11g.
A kind of preparation method for the treatment of hydronephrotic Chinese medicine composition tablet is:
(1) Periostracum Serpentis alum water is cleaned, dry, late with rice water leaching one, then be placed in pot, yellow wine spray is even, and low baking temperature is fried to yellow, and taking-up is dried in the air cool, pulverizes;
(2) infiltrated by Rhizoma Polygonati, section, get rice and put in frying pan, moderate heat is heated to a meter smoke, pours Rhizoma Polygonati sheet into, fries when becoming strong yellow to rice, takes out, and sieve removes rice, dries in the air cool, pulverizes;
(3) Talcum is removed roguing stone, clean, pound into fragment, be ground into fine powder, water flies, and dries;
(4) other residue medical materials except Periostracum Serpentis, Rhizoma Polygonati and Talcum are picked clean, drying, pulverizes respectively, made medicated powder and step (1), step (2) and step (3) made medicated powder is mixed, mix with pharmaceutical excipients, soft material processed, granulates, and dries, granulate, finally be pressed into oval tablet dosage form, the heavy 0.3g of every sheet, obtains tablet.
Model case: xxx, man, 43 years old.Main suit: be throughout the year engaged in physical work, diet work and rest is irregular, before half a year, sensation is dizzy, and dim eyesight, thinks heatstroke, back lumbar part pain increases the weight of, and occur persistence dull pain, edema appears in extremity, oliguria, frequent micturition, arrives examination in hospital then, light purplish tongue, yellow and thin fur, thready and stringy pulse, whole end and the kidney vertebral body top profile of ultrasound diagnosis display minor renal calices flatten smooth, and sinus renalis district has no echo area to show, and is finally diagnosed as moderate hydronephrosis.
Take the present embodiment gained one and treat hydronephrotic Chinese medicine composition tablet, every day 3 times, each 4-6 sheet, with warm water delivery service, 30 days courses for the treatment of.After taking a course for the treatment of, the malaise symptoms such as patient's lumbago, frequent micturition are alleviated to some extent, and edema obviously disappears, after continuing to take two courses for the treatment of, patient feels uneasy transference cure, and spirit is good, then arrives hospital and checks, surprisingly find, hydronephrosis disappears, and patient's Physico-chemical tests index is all normal, Rehabilitation.
embodiment 4one treats hydronephrotic Chinese medicine composition, is prepared from primarily of following bulk drugs: Periostracum Serpentis 16g, Herba pteridis vittatae 10g, Talcum 9.5g, Radix Streptocauli Griffithii 13g, Pollen Typhae 16g, Radix Aconiti Lateralis Preparata 14g, Rhizoma Polygonati 25g, Semen Vaccariae 13g, Herba Salviae Chinensis 10g, white Rhizoma Curculiginis 8g, Rhizoma Phragmitis 25g, Herba Euphorbiae Humifusae 14g, Rhizoma Smilacis Glabrae 18g, Herba Scutellariae Barbatae 12g, Cortex schizophragmatis integrifolii radicis 9g, Herba Crotalariae Ferrugineae 14g.
A kind of preparation method for the treatment of hydronephrotic Chinese medicine composition pill is:
(1) Periostracum Serpentis alum water is cleaned, dry, late with rice water leaching one, then be placed in pot, yellow wine spray is even, and low baking temperature is fried to yellow, and taking-up is dried in the air cool;
(2) infiltrated by Rhizoma Polygonati, section, get rice and put in frying pan, moderate heat is heated to a meter smoke, pours Rhizoma Polygonati sheet into, fries when becoming strong yellow to rice, takes out, and sieve removes rice, dries in the air cool, pulverizes;
(3) Talcum is removed roguing stone, clean, pound into fragment, be ground into fine powder, water flies, and dries;
(4) other residue medical materials except Periostracum Serpentis, Rhizoma Polygonati and Talcum are picked clean, dry, pulverize together with step (1) made medical material, medicated powder, get 2/3rds of made medicated powder and be placed in penetrating bag, add the soak by water 40 minutes of penetrating bag medicated powder quality 5 times, take out penetrating bag, obtain medicinal liquid;
(5) step (4) made medicine liquid heating is concentrated, mix with step (2) (3) made medicated powder and the medicated powder remaining 1/3rd, dry, pulverize, add refined honey, make pill.
Model case: xxx, man, 44 years old, patient once suffered from renal calculus before 3 years, and calculus is taken out in rear operation, but over nearly three months, there is frequent micturition in patient, lower abdomen pendant pain, renal colic, pressing increases the weight of, cold extremities, easily perspires, medical check then, B ultrasonic shows, the acute obstructive hydronephrosis that injury of ureter causes.
Take the present embodiment gained one and treat hydronephrotic Chinese medicine composition pill, every day 3 times, each 4-5 grain, with warm water delivery service, 30 days courses for the treatment of.After taking 20 days, patient's frequent micturition, lower abdomen pendant pain obviously alleviates, and after continuing to take two courses for the treatment of, all transference cures, B ultrasonic, CT check hydronephrosis and disappear, and ureter recovers normal.
embodiment 5one treats hydronephrotic Chinese medicine composition, is prepared from primarily of following bulk drugs: Periostracum Serpentis 13.5g, Herba pteridis vittatae 8.5g, Talcum 9g, Radix Streptocauli Griffithii 12g, Pollen Typhae 14g, Radix Aconiti Lateralis Preparata 12.5g, Rhizoma Polygonati 22.5g, Semen Vaccariae 12g, Herba Salviae Chinensis 9.5g, white Rhizoma Curculiginis 6.5g, Rhizoma Phragmitis 22.5g, Herba Euphorbiae Humifusae 12g, Rhizoma Smilacis Glabrae 15g, Herba Scutellariae Barbatae 11g, Cortex schizophragmatis integrifolii radicis 8g, Herba Crotalariae Ferrugineae 12.5g.
A kind of preparation method for the treatment of hydronephrotic Chinese medicine composition decoction is:
(1) get Herba Euphorbiae Humifusae and Herba Scutellariae Barbatae decontamination, be placed in frying pan, intense fire heats, parch surface coke brown, spray liquorice beverage, and go out most Mars, takes out, dry;
(2) Periostracum Serpentis alum water is cleaned, dry, late with rice water leaching one, then be placed in pot, yellow wine spray is even, and low baking temperature is fried to yellow, and taking-up is dried in the air cool;
(3) infiltrated by Rhizoma Polygonati, section, the rice getting quality of medicinal material 0.4 times is put in frying pan, and moderate heat is heated to a meter smoke, pours Rhizoma Polygonati sheet into, fries when becoming strong yellow to rice, takes out, and sieve removes rice, dries in the air cool;
(4) Radix Aconiti Lateralis Preparata is placed in marmite, decoct with water 40 minutes, then step (1), step (2) and step (3) made medical material and other residue medical materials except Herba Euphorbiae Humifusae, Herba Scutellariae Barbatae, Periostracum Serpentis, Rhizoma Polygonati and Radix Aconiti Lateralis Preparata are put into, wherein Pollen Typhae and Talcum are loaded in penetrating bag, add water and do not have medical material 3cm, after big fire is boiled, be adjusted to little fire and boil 50 minutes, Guan Huo, filters, obtains decoction.
test example 1gained one of the present invention treats the clinical practice of hydronephrotic Chinese medicine composition (embodiment 5):
455 routine patients are filtered out, wherein female 247 example, man 208 example, oldest 70 years old, minimal ages 41 years old, 58.6 years old mean age in hospital's urology department and Nephrology outpatient service.All experimenters are all diagnosed as hydronephrosis through B ultrasonic and CT examination, wherein mild hydronephrotic kidney 216 example, moderate hydrops person 186 example, severe hydrops person 53 example, wherein calculus person 68 example, inflammation 71 example.
Patient is divided into two groups at random, experimental group and matched group, two groups in sex, age, the course of disease, the state of an illness etc. without significant difference (P > 0.05), there is comparability.Experimental group takes products obtained therefrom of the present invention, and take every day twice (warm), each 60m1-90m1(adjusts to some extent depending on concrete condition), 30 days courses for the treatment of, matched group takes other medicine (conventional medication such as clean stone curing capsule, Australia's sweet smell, Xueniao Capsules).Period in a medicine carries out Continuous Observation to two groups of patients, record symptom and change.
Curative effect situation criterion: cure: clinical symptom disappearance, B ultrasonic, renal phlebography, CT check hydronephrosis and disappear or substantially disappear; Effective: clinical symptoms obviously alleviates, B ultrasonic, renal phlebography, CT check hydronephrosis and reduce 30%-80%; Invalid: symptom is improved not obvious or do not improved, and hydronephrosis reduces less than 30%.
Patient's therapeutic outcome after three courses for the treatment of of table 1
The therapeutic outcome that two groups of patient consumes treated after three courses for the treatment of is as shown in table 1, as can be seen from data, the clinical efficacy of experimental group is obviously better than matched group, and total effective rate is up to 97.0%, the total effective rate of matched group is that the difference between 81.3%, two groups has statistical significance.And the clinical symptoms improvement aspect of experimental group patient is also better than matched group, as the symptoms such as fear of cold, lumbago, the soreness of waist, edema are all improved significantly.
Periostracum Serpentis in formula of the present invention, Herba pteridis vittatae expelling wind for relieving convulsion, to invigorate blood circulation; Talcum, Radix Streptocauli Griffithii, Herba Salviae Chinensis, Herba Euphorbiae Humifusae, Rhizoma Smilacis Glabrae, Herba Scutellariae Barbatae heat-clearing and toxic substances removing, invigorating blood circulation analgesia, dehumidifying tonneau; Rhizoma Polygonati boosting qi and nourishing yin, tonifying speen and tonifying kidney; Semen Vaccariae promoting blood circulation to remove obstruction in the collateral; The spleen invigorating of white Rhizoma Curculiginis lung benefiting, by kidney and enhancing body; Rhizoma Phragmitis clearing away heat and promoting production of body fluid, diuresis; Herba Crotalariae Ferrugineae nourishing the liver and kidney, dampness removing, multiple medical material share, synergism, jointly plays heat-clearing and toxic substances removing, supports the effects such as kidney diuretic, the spleen strengthening and damp drying, therefore have significant curative effect for hydronephrosis.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.
Claims (10)
1. treat a hydronephrotic Chinese medicine composition, it is characterized in that, be prepared from primarily of following bulk drugs, be weight portion: Periostracum Serpentis 9-18, Herba pteridis vittatae 5-12, Talcum 8-10, Radix Streptocauli Griffithii 9-15, Pollen Typhae 10-18, Radix Aconiti Lateralis Preparata 9-16, Rhizoma Polygonati 15-30, Semen Vaccariae 9-15, Herba Salviae Chinensis 7-12, white Rhizoma Curculiginis 4-9, Rhizoma Phragmitis 15-30, Herba Euphorbiae Humifusae 8-16, Rhizoma Smilacis Glabrae 10-20, Herba Scutellariae Barbatae 8-14, Cortex schizophragmatis integrifolii radicis 6-10, Herba Crotalariae Ferrugineae 10-15.
2. one as claimed in claim 1 treats hydronephrotic Chinese medicine composition, it is characterized in that, Periostracum Serpentis 11-16, Herba pteridis vittatae 7-10, Talcum 8.5-9.5, Radix Streptocauli Griffithii 11-13, Pollen Typhae 12-16, Radix Aconiti Lateralis Preparata 11-14, Rhizoma Polygonati 20-25, Semen Vaccariae 11-13, Herba Salviae Chinensis 9-10, white Rhizoma Curculiginis 5-8, Rhizoma Phragmitis 20-25, Herba Euphorbiae Humifusae 10-14, Rhizoma Smilacis Glabrae 12-18, Herba Scutellariae Barbatae 10-12, Cortex schizophragmatis integrifolii radicis 7-9, Herba Crotalariae Ferrugineae 11-14 is (preferred, Periostracum Serpentis 13.5, Herba pteridis vittatae 8.5, Talcum 9, Radix Streptocauli Griffithii 12, Pollen Typhae 14, Radix Aconiti Lateralis Preparata 12.5, Rhizoma Polygonati 22.5, Semen Vaccariae 12, Herba Salviae Chinensis 9.5, white Rhizoma Curculiginis 6.5, Rhizoma Phragmitis 22.5, Herba Euphorbiae Humifusae 12, Rhizoma Smilacis Glabrae 15, Herba Scutellariae Barbatae 11, Cortex schizophragmatis integrifolii radicis 8, Herba Crotalariae Ferrugineae 12.5).
3. the one as described in as arbitrary in claim 1-2 treats hydronephrotic Chinese medicine composition, and it is characterized in that, be made into pharmaceutically acceptable decoction, its preparation method is:
(1) get Herba Euphorbiae Humifusae and Herba Scutellariae Barbatae decontamination, be placed in frying pan, intense fire heats, parch surface coke brown, spray liquorice beverage, and go out most Mars, takes out, dry;
(2) Periostracum Serpentis alum water is cleaned, dry, late with rice water leaching one, then be placed in pot, yellow wine spray is even, and low baking temperature is fried to yellow, and taking-up is dried in the air cool;
(3) infiltrated by Rhizoma Polygonati, section, get rice and put in frying pan, moderate heat is heated to a meter smoke, pours Rhizoma Polygonati sheet into, fries when becoming strong yellow to rice, takes out, and sieve removes rice, dries in the air cool;
(4) Radix Aconiti Lateralis Preparata is placed in marmite, decoct with water 40 minutes, then step (1), step (2) and step (3) made medical material and other residue medical materials except Herba Euphorbiae Humifusae, Herba Scutellariae Barbatae, Periostracum Serpentis, Rhizoma Polygonati and Radix Aconiti Lateralis Preparata are put into, wherein Pollen Typhae and Talcum are loaded in penetrating bag, add water and do not have medical material 3cm, after big fire is boiled, be adjusted to little fire boil 40-60 minute (preferred, be adjusted to little fire and boil 45-55 minute; Be more preferably, be adjusted to little fire and boil 50 minutes), Guan Huo, filters, obtains decoction.
4. a kind of preparation method for the treatment of hydronephrotic Chinese medicine composition decoction as claimed in claim 3, it is characterized in that, the amount of step (3) rice is 0.4 times of quality of medicinal material.
5. the one as described in as arbitrary in claim 1-2 treats hydronephrotic Chinese medicine composition, and it is characterized in that, be made into pharmaceutically acceptable powder, its preparation method is:
(1) get Herba Euphorbiae Humifusae and Herba Scutellariae Barbatae decontamination, be placed in frying pan, intense fire heats, parch surface coke brown, spray liquorice beverage, and go out most Mars, takes out, dry;
(2) Periostracum Serpentis alum water is cleaned, dry, late with rice water leaching one, then be placed in pot, yellow wine spray is even, and low baking temperature is fried to yellow, and taking-up is dried in the air cool;
(3) infiltrated by Rhizoma Polygonati, section, get rice and put in frying pan, moderate heat is heated to a meter smoke, pours Rhizoma Polygonati sheet into, fries when becoming strong yellow to rice, takes out, and sieve removes rice, dries in the air cool;
(4) Radix Aconiti Lateralis Preparata is placed in marmite, decoct with water 40 minutes, then step (1), step (2) and step (3) made medical material and other residue medical materials except Herba Euphorbiae Humifusae, Herba Scutellariae Barbatae, Periostracum Serpentis, Rhizoma Polygonati and Radix Aconiti Lateralis Preparata are put into, wherein Pollen Typhae and Talcum are loaded in penetrating bag, add water and do not have medical material 3cm, after big fire is boiled, be adjusted to little fire boil 40-60 minute (preferred, be adjusted to little fire and boil 45-55 minute; Be more preferably, be adjusted to little fire and boil 50 minutes), Guan Huo, filters;
(5) step (4) remaining medicinal residues and penetrating bag are added water, decoct 30 minutes, filter, merge twice filtrate, heating is concentrated, and spraying dry, pulverizes and sieves, and obtains powder.
6. a kind of preparation method for the treatment of hydronephrotic Chinese medicine composition composition powders as claimed in claim 5, is characterized in that, step (5) pulverized 80-120 mesh sieve (preferred, pulverized 90-110 mesh sieve; Be more preferably, pulverized 100 mesh sieves).
7. the one as described in as arbitrary in claim 1-2 treats hydronephrotic Chinese medicine composition, and it is characterized in that, be made into pharmaceutically acceptable tablet, its preparation method is:
(1) Periostracum Serpentis alum water is cleaned, dry, late with rice water leaching one, then be placed in pot, yellow wine spray is even, and low baking temperature is fried to yellow, and taking-up is dried in the air cool, pulverizes;
(2) infiltrated by Rhizoma Polygonati, section, get rice and put in frying pan, moderate heat is heated to a meter smoke, pours Rhizoma Polygonati sheet into, fries when becoming strong yellow to rice, takes out, and sieve removes rice, dries in the air cool, pulverizes;
(3) Talcum is removed roguing stone, clean, pound into fragment, be ground into fine powder, water flies, and dries;
(4) other residue medical materials except Periostracum Serpentis, Rhizoma Polygonati and Talcum are picked clean, dry, pulverize respectively, made medicated powder and step (1), step (2) and step (3) made medicated powder are mixed, mixes with pharmaceutical excipients, soft material processed, granulate, dry, granulate, finally be pressed into oval tablet dosage form, obtain tablet.
8. a kind of preparation method for the treatment of hydronephrotic Chinese medicine composition tablet as claimed in claim 7, is characterized in that, heavy 0.25-0.35g(is preferred for the every sheet of step (4) made tablet, the heavy 0.3g of the every sheet of tablet).
9. the one as described in as arbitrary in claim 1-2 treats hydronephrotic Chinese medicine composition, and it is characterized in that, be made into pharmaceutically acceptable pill, its preparation method is:
(1) Periostracum Serpentis alum water is cleaned, dry, late with rice water leaching one, then be placed in pot, yellow wine spray is even, and low baking temperature is fried to yellow, and taking-up is dried in the air cool;
(2) infiltrated by Rhizoma Polygonati, section, get rice and put in frying pan, moderate heat is heated to a meter smoke, pours Rhizoma Polygonati sheet into, fries when becoming strong yellow to rice, takes out, and sieve removes rice, dries in the air cool, pulverizes;
(3) Talcum is removed roguing stone, clean, pound into fragment, be ground into fine powder, water flies, and dries;
(4) other residue medical materials except Periostracum Serpentis, Rhizoma Polygonati and Talcum are picked clean, dry, pulverize together with step (1) made medical material, obtain medicated powder, get 2/3rds of made medicated powder and be placed in penetrating bag, add the soak by water of penetrating bag medicated powder quality 5 times, take out penetrating bag, obtain medicinal liquid;
(5) step (4) made medicine liquid heating is concentrated, mix with step (2) (3) made medicated powder and the medicated powder remaining 1/3rd, dry, pulverize, add refined honey, make pill.
10. a kind of preparation method for the treatment of hydronephrotic Chinese medicine composition pill as claimed in claim 9, is characterized in that, step (4) decoct with water 30-50 minute (preferred, decoct with water 35-45 minute; Be more preferably, decoct with water 40 minutes).
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