CN104606436A - Traditional Chinese medicine composition for treating senility diabetes mellitus - Google Patents
Traditional Chinese medicine composition for treating senility diabetes mellitus Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition for treating senility diabetes mellitus. The traditional Chinese medicine composition for treating senility diabetes mellitus comprises the following raw materials in parts by weight: 28 to 32 parts of astragali radix, 28 to 32 parts of pseudostellaria heterophylla, 28 to 32 parts of radix rehmanniae, 28 to 32 parts of prepared rhizome of rehmannia, 13 to 17 parts of fructus corni, 28 to 32 parts of rhizoma discoreae, 13 to 17 parts of herba epimedii, 13 to 17 parts of semen cuscutae, 28 to 32 parts of radix salviae miltiorrhizae, 13 to 17 parts of Chinese angelica, 28 to 32 parts of kudzuvine roots, 28 to 32 parts of the fruits of Chinese wolfberry, and 5 to 7 parts of radix glycyrrhizae preparata. The traditional Chinese medicine composition used for curing senility diabetes mellitus can effectively cure diabetes and comprehensively condition metabolic disturbance, has a certain repairing effect to pancreatic tissue impair, takes a pancreas islet restoring function as a major, can promote the releasing of insulin, and can balance hyperglycemia level.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicine preparation, particularly relate to a kind of Chinese medicine composition being used for the treatment of old-aged diabetes.
Background technology
Diabetes, " diabetes " namely alleged by the traditional Chinese medical science is a kind of take hyperglycemia as the common incretion metabolism disease of common trait, due to insulin definitely or relative deficiency and causing, its main clinical symptoms is: polyuria, polydipsia, polyphagia, become thin.Compared with non-diabetic people, doubly, ulcer of the lower limb and amputation rate, exceed 20 times to the high 2-5 of the cardiovascular and cerebrovascular disease of diabetes patient, blind sickness rate and mortality rate thereof especially.At present, diabetes have become the third-largest non-infective disease after developed country's relaying cardiovascular disease and tumor, are the worldwide public health problems of serious threat human health.
Just morbidity that old-aged diabetes comprises 60 years old later or morbidity in the past in 60 years old and after extending to 60 years old.Non-insulin-dependent is main.Old and non-aged diabetes have a lot of common ground, but senile diabetes also has its many feature.Old-aged diabetic with various diseases, application multi-medicament, intelligence and hypomnesis, often asymptomatic or atypical symptom, even or cover up by other chronic diseases.Along with aged tendency of population, the prevalence of senile diabetes certainly will increase, and the complication of sensile diabetic patient is comparatively common, and M & M is higher.For the feature of old-aged diabetes, clinical with market all in the urgent need to a kind of medicine of efficient treatment diabetes.
Summary of the invention
Based on the technical problem that background technology exists, the present invention proposes a kind of Chinese medicine composition being used for the treatment of old-aged diabetes, effectively can treat diabetes, comprehensive conditioning metabolism disorder, certain repair is had to pancreatic tissue damage, to recover islet function, impel insulin releasing, balance blood sugar level.
A kind of Chinese medicine composition being used for the treatment of old-aged diabetes that the present invention proposes, its raw material comprises by weight: Radix Astragali 28-32 part, Radix Pseudostellariae 28-32 part, Radix Rehmanniae 28-32 part, Radix Rehmanniae Preparata 28-32 part, Fructus Corni 13-17 part, Rhizoma dioscoreae 28-32 part, Herba Epimedii 13-17 part, Semen Cuscutae 13-17 part, Radix Salviae Miltiorrhizae 28-32 part, Radix Angelicae Sinensis 13-17 part, Radix Puerariae 28-32 part, baogan medlar 28-32 part, Radix Glycyrrhizae Preparata 5-7 part.
Radix Astragali, for leguminous plant Inner Mongol Radix Astragali, film pod Radix Astragali or other belong to the root of close kind of plant together.Sweet in the mouth, slightly warm in nature.Enter spleen, lung meridian.There is tonifying Qi and lifting yang, strengthening superficial resistance to stop perspiration, holder skin ulcer granulation promoting, effect of diuretic detumescent.Be used for the treatment of the deficiency of vital energy weak, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, carbuncle difficulty is burst, and burst for a long time and do not hold back, blood deficiency and yellow complexion, interior-heat is quenched one's thirst, chronic nephritis, albuminuria, diabetes etc.
Radix Pseudostellariae is the tuber of pinkwort pseudostellaria heterophylla.Summer, stem and leaf major part withered peacefully to be excavated, and cleaned, removing fibrous root, put and to dry in the shade after slightly scalding in boiling water or directly dry.Sweet in the mouth, micro-hardship, slightly warm in nature.Enter lung, spleen channel.There is benefit strengthening spleen and lung, effect of supplementing QI for promoting the production of body fluid.Cure mainly cough due to deficiency of the lung, insufficiency of the spleen lack of appetite, cardiopalmus, palpitation with a distress feeling, edema, quenches one's thirst, metal fatigue.It joins the Radix Astragali, and the effect of tonification increases, and conventional to control overstrain weak be effect.
The Radix Rehmanniae is the root of Scrophulariaceae herbaceous plant Radix Rehmanniae.Originate in Henan, Hebei, the Inner Mongol and northeast.Autumn excavates.Clean raw using or dry use, claim Radix Rehmanniae, or be called for short the Radix Rehmanniae.Sweet-bitter flavor, cool in nature.Enter the heart, liver, kidney channel.There is heat clearing away, promote the production of body fluid, YIN nourishing, the effect nourished blood.Cure mainly fever due to yin deficiency, quench one's thirst, spit blood, epistaxis, metrorrhagia, menoxenia, frequent fetal movement, the moon hinders constipation.
Radix Rehmanniae Preparata, for the tuber of scrophulariaceae rehmannia glutinosa plant forms through Processing methods.Usually with wine, Fructus Amomi, Pericarpium Citri Reticulatae for adjuvant is through repeatedly steaming solarization, to inside and outside darkish complexion glossy, quality softness is sticky.Section use, or parch to black is used.After concocting, the property of medicine turns tepor by being slightly cold, and tonification strengthens.Sweet in the mouth; Warm in nature.Return liver; Kidney channel.Have and enrich blood moist, beneficial essence fills out effect of marrow.For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, hepatic and renal YIN deficiency, hectic fever night sweat, seminal emission sexual impotence, infertility, menoxenia, metrostaxis, soreness of the waist and knees, Hiccough and deaf, the head is dim-sighted, early whitening of beard and hair, quenches one's thirst, constipation, dyspnea with rapid and short breath of suffering from a deficiency of the kidney.
Fructus Corni is the drying and ripening sarcocarp of Cornaceae plant Fructus Corni.Sour in the mouth, puckery, slightly warm in nature.Return liver, kidney channel.There is liver and kidney tonifying, the function of essence astringing and desertion stemming.For vertigo and tinnitus, soreness of waist and knee joint, impotence and seminal emission, enuresis frequent micturition, bleeding not during menses, profuse sweating is collapsed.Interior-heat is quenched one's thirst.
Rhizoma dioscoreae is the rhizome of monocotyledon Dioscoreaceae Rhizoma Dioscoreae.Autumn or winter take rhizome, and removing earth, fibrous root, cut removing LU, cleans, and with rossing after water logging, after repeatedly smoking with sulfur, dry.Have after sulfur is smoked, be twisted into plank cylindrical, cutting, dry, polishing.Sweet in the mouth, property is put down.Return spleen, lung, kidney channel.There is strengthening the spleen and tonifying the lung, stomach reinforcing the kidney invigorating, benefit of reinforcing the kidney essence, hearing-improing and eyesight improving, help the five internal organs, bone and muscle strengthening, long will are calmed the nerves, effect of life lengthening; Cure mainly that weakness of the spleen and stomach, lassitude, inappetence, chronic diarrhea and dysentery, insufficiency of lung-QI are dry, phlegm dyspnea cough, kidney qi loss, soreness of the waist and knees, lower limb flaccidity be weak, the red disease such as swollen, fat of frequent micturition of quenching one's thirst, seminal emission premature ejaculation, leukorrhagia nebulousurine, skin.
Herba Epimedii, is also called Herba Epimedii, is Berberidaceae plant Epimedium brevicornum, the dry aerial parts of Herba Epimedii, Epimedium sagittatum, E. Pubescens, Epimedium wushanense or Herba Epimedii.Tap when summer, autumn, stem and leaf was luxuriant, the thick stalk of removing and impurity, dry or dry in the shade.Acrid in the mouth, sweet, warm in nature.Return liver, kidney channel.Energy kidney-replenishing, bone and muscle strengthening, wind-damp dispelling.For impotence and seminal emission, muscles and bones flaccidity is soft, rheumatic arthralgia, numbness contracture; Climacteric hypertension.
Semen Cuscutae is the seed of convolvulus cuscuta plant.During seed maturity summer and autumn, cut off together with host, dry, lay seed, removing impurity.Sweet in the mouth, warm in nature.Enter liver, kidney channel.Energy nourishing the liver and kidney, controlling nocturnal emission with astringent drugs reducing urination, antiabortive, improving eyesight, antidiarrheal.Suffer from a deficiency of the kidney rush down for impotence and seminal emission, dripping urination, enuresis frequent micturition, soreness of the waist and knees, blurred vision tinnitus, vaginal bleeding due to deficiency of the kidney during pregnancy, frequent fetal movement, spleen; Externally treating leucoderma.
Radix Salviae Miltiorrhizae, i.e. Radix Salviae Miltiorrhizae are the dry root and rhizome of dicotyledon Labiatae Radix Salviae Miltiorrhizae.Bitter in the mouth, cold nature.GUIXIN, Liver Channel.Have promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing, removing heat from blood eliminating carbuncle, clear away heart-fire relieving restlessness, effect of nourishing blood to tranquillize the mind.Cure mainly menoxenia, amenorrhea dysmenorrhea, lump in the abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia; Hepatosplenomegaly, angina pectoris.
Radix Angelicae Sinensis is the root of umbelliferae angelica.Hide sweet, pungent, warm in nature.Return liver, the heart, spleen channel.Can enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.
Radix Puerariae is the root of leguminous plant Pachyrhizua angulatus.Sweet in the mouth, pungent, property is put down.Enter spleen, stomach warp.Can induce sweat, rash, promotes the production of body fluid, antidiarrheal.For fever caused by exogenous pathogens headache, hypertension neck pain, thirsty, quench one's thirst, measles without adequate eruption, hematodiarrhoea, to have loose bowels.
Baogan medlar, i.e. Fructus Lycii, also known as Fructus Lycii, are the dry mature fruit of plant of Solanaceae lycium barbarum.Summer, autumn two gather when season, fruit took on a red color, hot-air seasoning, removing carpopodium.Or dry in the air to rhicnosis, dry, removing carpopodium.Sweet in the mouth, property is put down.Return liver, kidney channel.Energy nourishing the liver and kidney, replenishing vital essence to improve eyesight.For asthenia damage of essence, soreness of waist and knee joint, vertigo and tinnitus, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, and blurred vision is failed to understand.
Radix Glycyrrhizae Preparata, then Radix Glycyrrhizae tabellae Mel of making a living is mixed thoroughly, then fries to tack-free taking-up airing, person of not being used as medicine.Relatively lung moistening and in.Property is put down, and sweet in the mouth, returns 12 warps.Energy invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Preferably, the weight ratio of Radix Astragali, Radix Pseudostellariae, the Radix Rehmanniae and Radix Rehmanniae Preparata is 29-31:29-31:29-31:29-31.
Preferably, its raw material comprises by weight: Radix Astragali 29-31 part, Radix Pseudostellariae 29-31 part, Radix Rehmanniae 29-31 part, Radix Rehmanniae Preparata 29-31 part, Fructus Corni 14-16 part, Rhizoma dioscoreae 29-31 part, Herba Epimedii 14-16 part, Semen Cuscutae 14-16 part, Radix Salviae Miltiorrhizae 29-31 part, Radix Angelicae Sinensis 14-16 part, Radix Puerariae 29-31 part, baogan medlar 29-31 part, Radix Glycyrrhizae Preparata 5-7 part.
Preferably, the weight ratio of Herba Epimedii, Semen Cuscutae, Radix Salviae Miltiorrhizae and Radix Angelicae Sinensis is 1:1:2:1.
Preferably, its raw material comprises by weight: Radix Astragali 30 parts, Radix Pseudostellariae 30 parts, 30 parts, the Radix Rehmanniae, 30 parts, Radix Rehmanniae Preparata, Fructus Corni 15 parts, Rhizoma dioscoreae 30 parts, Herba Epimedii 15 parts, Semen Cuscutae 15 parts, Radix Salviae Miltiorrhizae 30 parts, Radix Angelicae Sinensis 15 parts, Radix Puerariae 30 parts, baogan medlar 30 parts, Radix Glycyrrhizae Preparata 6 parts.
Preferably, also comprise: Radix Ophiopogonis 6-12 part, Rhizoma Polygonati Odorati 6-12 part, Rhizoma Anemarrhenae 6-12 part.
Radix Ophiopogonis, having another name called dwarf lilyturf, book band grass, Radix Ophiopogonis, is Liliaceae Ophiopogon perennial evergreen herbaceous plant.Sweet in the mouth, micro-hardship, cold nature.GUIXIN, lung, stomach warp.Energy YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire.For dryness of the lung dry cough, chronic consumptive disease is coughed, and Tianjin wound is thirsty, and vexed insomnia, interior-heat is quenched one's thirst, dryness of the intestine constipation, pharyngeal diphtheria.
Rhizoma Polygonati Odorati is the rhizome of liliaceous plant Rhizoma Polygonati Odorati.Sweet in the mouth, property is put down.Enter lung, stomach warp.There is nourishing YIN and moistening the lung, effect of nourishing the stomach to promote the production of body fluid.Injured for lung yin, xeropulmonary cough, the few expectorant of dry cough, and stomach excessive heat, Tianjin wound is thirsty, and rapid digestion of food is easily hungry waits disease.
The Rhizoma Anemarrhenae is the dry rhizome of the monocotyledon Liliaceae Rhizoma Anemarrhenae.Season in spring and autumn two all can excavate, and removing fibrous root and silt, dry, and practises and claims " RHIZOMA ANEMARRHENAE with peet "; Or removing crust, dry.Put aeration-drying place, moistureproof, be used as medicine in order to section, raw use, or use processed by saline.Bitter in the mouth, sweet, cold in nature.Return lung, stomach, kidney channel.Energy clearing away heat-fire, promotes the production of body fluid and moisturizes.For fever caused by exogenous pathogenic factors, high hot excessive thirst, lung-heat type cough, osteopyrexia and fever, interior-heat is quenched one's thirst, dryness of the intestine constipation.
Preferably, also comprise: Ramulus Cinnamomi 3-9 part, Radix Aconiti Lateralis Preparata 3-9 part, Colla cornus cervi 6-12 part.
Ramulus Cinnamomi is the dry twig of Lauraceae aiphyllium plant Cortex Cinnamomi.Acrid in the mouth, sweet, warm in nature.GUIXIN, lung, urinary bladder channel.Energy diaphoresis expelling pathogenic factors from muscles, warming the meridian and promoting blood circulation, supporing yang activating QI, dispersing cold for relieving pain.For anemofrigid cold, coldness and pain in the epigastrium, cold in blood amenorrhea, arthralgia, phlegm retention, edema, cardiopalmus, renal mass.
Radix Aconiti Lateralis Preparata, also known as Radix Aconiti Lateralis Preparata, is the daughter root of ranunculaceae plant Aconitum carmichjaelii Debx..Acrid in the mouth, sweet, extremely hot in nature; Poisonous.GUIXIN, kidney channel.Energy recuperating depleted YANG and rescuing the patient from collapse, mends fire supporing yang, dispersing cold for relieving pain.For excessive YIN keeping YANG externally, loss of YANG due to profuse perspiration, vomiting and diarrhoea, it is inverse to faint, cold extremities faint pulse, trusted subordinate's cold type of pain, cold-dysentery, beriberi edema, anemofrigid-damp arthralgia, sexual impotence, cold womb, and deficiency and coldness is vomited and diarrhoea, YIN-cold edema, yang deficiency diseases caused by exogenous pathogenic factor, the disease of carbuncle of yin nature skin infection and all chronic diseaseses.
Colla cornus cervi, the blob of viscose that the angle for animal in deer family Cervus nippon Temminck or Cervus elaphus linnaeus decocts.Sweet-salty, warm in nature.Enter liver, kidney channel.Can enrich blood, benefit essence.Cure mainly deficiency of kidney-QI, asthenia weakness and emaciation, lumbago, carbuncle of yin nature, impotence in male, spermatorrhea, uterus cold caused by deficiency, metrorrhagia, leukorrhagia.
Preferably, also comprise: Semen Persicae 6-9 part, Flos Carthami 3-6 part.
Semen Persicae is the dry mature seed of rosaceous plant Fructus Persicae or Prunus davidiana.Gather after fruit maturation, removing sarcocarp and nucleocapsid, take out seed, dry.Bitter in the mouth, sweet, property is put down.GUIXIN, liver, large intestine channel.Energy blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation, relieving cough and asthma.For amenorrhea, dysmenorrhea ， WEIJIA mass in the abdomen, injury from falling down, dryness of the intestine constipation.
Flos Carthami is the dried floral of feverfew Flos Carthami.Warm in nature, acrid in the mouth.Return liver, heart channel.To invigorate blood circulation latus rectum, eliminating stasis to stop pain.For amenorrhea, dysmenorrhea, lochia, lump in the abdomen mass in the abdomen, traumatic injury.
The present invention, with Radix Pseudostellariae, the Radix Rehmanniae, Radix Puerariae compatibility, mends strengthening spleen and lung, supplementing QI for promoting the production of body fluid; Use again the mutual compatibility of Radix Astragali, Fructus Corni, Rhizoma dioscoreae, Herba Epimedii, Semen Cuscutae, baogan medlar, tonifying Qi and lifting yang, enrich blood moist, benefit essence fills out marrow, strengthening the spleen and tonifying the lung, stomach reinforcing the kidney invigorating, and the Radix Rehmanniae, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae cooperatively interact, to enrich blood nourishing blood and promoting blood circulation, YIN nourishing menstruction regulating and pain relieving, Radix Glycyrrhizae Preparata, invigorating the spleen and replenishing QI, coordinating the actions of various ingredients in a prescription, relatively lung moistening and in; Above-mentioned all recurrence due to taking drug are joined, and for the etiology and pathogenesis of old people's diabetes, clearing away heat and promoting production of body fluid, nourishing YIN and supplementing blood, strengthening the spleen and tonifying the lung, nourishing the liver and kidney, promoting blood flow to regulate menstruation, reaches the effect for the treatment of both the principal and secondary aspects of a disease.Can adjust compositions for patients symptomatic, as patient's asthenic fire is excessively prosperous, can increase Radix Ophiopogonis, Rhizoma Polygonati Odorati, the Rhizoma Anemarrhenae, YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire, fire-draining and dryness moisturizing; As patient's coldness of the body with chills, Ramulus Cinnamomi, Radix Aconiti Lateralis Preparata, Colla cornus cervi can be increased, diaphoresis expelling pathogenic factors from muscles, warming the meridian and promoting blood circulation, supporing yang activating QI, dispersing cold for relieving pain, enriching blood and replenishing vital essence; As crisp in patient's limb fiber crops tongue, Semen Persicae Flos Carthami can be increased, blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation, relieving cough and asthma.
The present invention is through experimental results demonstrate, Chinese medicine composition provided by the invention can be used for treating human diabetes, has the effect reducing blood glucose and protection pancreas.Compared with the diabetes pill containing western medicine component glibenclamide, although its effect quite or slightly weak, but because of containing western medicine composition glibenclamide, diabetes pill is taken improper, can cause hypoglycemia untoward reaction clinically, and Chinese medicine composition of the present invention is pure Chinese medicine composition, not containing any Western medicine, our experiments show that there is no obvious untoward reaction, be more suitable for being used for the treatment of old-aged diabetes clinically.
Detailed description of the invention
Below, by specific embodiment, technical scheme of the present invention is described in detail.
Embodiment 1
A kind of Chinese medicine composition being used for the treatment of old-aged diabetes that the present invention proposes, its raw material comprises by weight: Radix Astragali 28 parts, Radix Pseudostellariae 32 parts, 28 parts, the Radix Rehmanniae, 32 parts, Radix Rehmanniae Preparata, Fructus Corni 13 parts, Rhizoma dioscoreae 32 parts, Herba Epimedii 13 parts, Semen Cuscutae 17 parts, Radix Salviae Miltiorrhizae 28 parts, Radix Angelicae Sinensis 17 parts, Radix Puerariae 28 parts, baogan medlar 32 parts, Radix Glycyrrhizae Preparata 5 parts, Radix Ophiopogonis 12 parts, Rhizoma Polygonati Odorati 6 parts, the Rhizoma Anemarrhenae 12 parts.
Embodiment 2
A kind of Chinese medicine composition being used for the treatment of old-aged diabetes that the present invention proposes, its raw material comprises by weight: Radix Astragali 32 parts, Radix Pseudostellariae 28 parts, 32 parts, the Radix Rehmanniae, 28 parts, Radix Rehmanniae Preparata, Fructus Corni 17 parts, Rhizoma dioscoreae 28 parts, Herba Epimedii 17 parts, Semen Cuscutae 13 parts, Radix Salviae Miltiorrhizae 32 parts, Radix Angelicae Sinensis 13 parts, Radix Puerariae 32 parts, baogan medlar 28 parts, Radix Glycyrrhizae Preparata 7 parts, Radix Ophiopogonis 6 parts, Rhizoma Polygonati Odorati 12 parts, the Rhizoma Anemarrhenae 6 parts.
Embodiment 3
A kind of Chinese medicine composition being used for the treatment of old-aged diabetes that the present invention proposes, its raw material comprises by weight: Radix Astragali 29 parts, Radix Pseudostellariae 31 parts, 29 parts, the Radix Rehmanniae, 31 parts, Radix Rehmanniae Preparata, Fructus Corni 14 parts, Rhizoma dioscoreae 31 parts, Herba Epimedii 14 parts, Semen Cuscutae 16 parts, Radix Salviae Miltiorrhizae 29 parts, Radix Angelicae Sinensis 16 parts, Radix Puerariae 29 parts, baogan medlar 31 parts, Radix Glycyrrhizae Preparata 5 parts, Ramulus Cinnamomi 9 parts, Radix Aconiti Lateralis Preparata 3 parts, Colla cornus cervi 12 parts.
Embodiment 4
A kind of Chinese medicine composition being used for the treatment of old-aged diabetes that the present invention proposes, its raw material comprises by weight: Radix Astragali 31 parts, Radix Pseudostellariae 29 parts, 31 parts, the Radix Rehmanniae, 29 parts, Radix Rehmanniae Preparata, Fructus Corni 16 parts, Rhizoma dioscoreae 29 parts, Herba Epimedii 16 parts, Semen Cuscutae 14 parts, Radix Salviae Miltiorrhizae 31 parts, Radix Angelicae Sinensis 14 parts, Radix Puerariae 31 parts, baogan medlar 29 parts, Radix Glycyrrhizae Preparata 7 parts, Ramulus Cinnamomi 3 parts, Radix Aconiti Lateralis Preparata 9 parts, Colla cornus cervi 6 parts.
Embodiment 5
A kind of Chinese medicine composition being used for the treatment of old-aged diabetes that the present invention proposes, its raw material comprises by weight: Radix Astragali 30 parts, Radix Pseudostellariae 30 parts, 30 parts, the Radix Rehmanniae, 30 parts, Radix Rehmanniae Preparata, Fructus Corni 15 parts, Rhizoma dioscoreae 30 parts, Herba Epimedii 15 parts, Semen Cuscutae 15 parts, Radix Salviae Miltiorrhizae 30 parts, Radix Angelicae Sinensis 15 parts, Radix Puerariae 30 parts, baogan medlar 30 parts, Radix Glycyrrhizae Preparata 6 parts, 9 parts, Semen Persicae, 3 parts, Flos Carthami.
Embodiment 6
A kind of Chinese medicine composition being used for the treatment of old-aged diabetes that the present invention proposes, its raw material comprises by weight: Radix Astragali 30 parts, Radix Pseudostellariae 30 parts, 30 parts, the Radix Rehmanniae, 30 parts, Radix Rehmanniae Preparata, Fructus Corni 15 parts, Rhizoma dioscoreae 30 parts, Herba Epimedii 15 parts, Semen Cuscutae 15 parts, Radix Salviae Miltiorrhizae 30 parts, Radix Angelicae Sinensis 15 parts, Radix Puerariae 30 parts, baogan medlar 30 parts, Radix Glycyrrhizae Preparata 6 parts, 6 parts, Semen Persicae, 6 parts, Flos Carthami.
Embodiment 7
A kind of Chinese medicine composition being used for the treatment of old-aged diabetes that the present invention proposes, its raw material comprises by weight: Radix Astragali 30g, Radix Pseudostellariae 30g, Radix Rehmanniae 30g, Radix Rehmanniae Preparata 30g, Fructus Corni 15g, Rhizoma dioscoreae 30g, Herba Epimedii 15g, Semen Cuscutae 15g, Radix Salviae Miltiorrhizae 30g, Radix Angelicae Sinensis 15g, Radix Puerariae 30g, baogan medlar 30g, Radix Glycyrrhizae Preparata 6g.
Selecting to be diagnosed as type ii diabetes patient 100 example is for the first time object of study, and all objects including research in meet the diagnostic criteria of diabetes, belong to type ii diabetes, make a definite diagnosis for the first time, informed consent.Get rid of and there is the patient of diabetic complication through electrocardiogram, routine urinalysis, Measure blood pressure, ophthalmologic examination etc. and there is the patient of motion contraindication.The object including research in is divided at random seminar 50 example and matched group 50 example.Seminar man 27 example, female 23 example, 66.8 ± 8.4 years old mean age; Matched group man 16 example, female 14 example, 67.1 ± 7.9 years old mean age.Two groups of Gender ratios, mean age comparing difference not statistically significants (P > 0.05).
Matched group gives to adjust life style, accomplishes Energy intaking and consumes in a basic balance; And giving the treatment of patient's oral administration of metformin sheet, each 500mg, 3 times/d is oral.According to conditions of patients adjustment dosage in therapeutic process.Seminar gives embodiment 7 on the basis of matched group, carrying out boiling, when boiling to decoction residue 2500ml, filtering adding water after above-mentioned raw material of Chinese medicine mixing and obtaining the Chinese medicine decoction being used for the treatment of old-aged diabetes, being divided into and taking for early, middle and late three times.
After 3 months, two groups of patient clinical curative effects are evaluated.Before intervention and after intervening, detect patient's fasting glucose, 2h-plasma glucose (2hPG), fasting insulin (FINS) respectively, calculate insulin resistance index (HOMA-IR).Its result is as follows:
Two groups of Clinical efficacy comparison results are as follows:
| Group | n | Effective | Effectively | Invalid | Effectively total |
| Seminar | 50 | 16(32％) | 31(62％) | 3(6％) | 47(94％) |
| Matched group | 50 | 10(20％) | 22(44％) | 18(36％) | 32(64％) |
Wherein, evaluation of clinical curative effect method: effective: fasting glucose and 2h-plasma glucose are down to normal range; Effective: before fasting glucose and 2h-plasma glucose decline > treat 20%, but do not reach normal level; Invalid: fasting glucose and 2h-plasma glucose are without decline, or fall does not reach effective standard.
Seminar's total effective rate 94%, matched group total effective rate 64%, two groups of comparing differences have remarkable statistical significance (P < 0.01).Before and after treatment, compare in two groups of groups, all significantly improve before FBG, 2hPG, FINS and HOMA-IR comparatively treat (P < 0.01); And seminar improves more obvious, after treatment, seminar FBG, 2hPG, FIN, HOMA-IR are all remarkable in matched group.Thus can reach a conclusion: Senile Diabetes Patients takes the present invention on basis of conventional therapy, significantly can improve blood sugar level, improve insulin resistance condition.
The above; be only the present invention's preferably detailed description of the invention; but protection scope of the present invention is not limited thereto; anyly be familiar with those skilled in the art in the technical scope that the present invention discloses; be equal to according to technical scheme of the present invention and inventive concept thereof and replace or change, all should be encompassed within protection scope of the present invention.
Claims (8)
1. be used for the treatment of a Chinese medicine composition for old-aged diabetes, it is characterized in that, its raw material comprises by weight: Radix Astragali 28-32 part, Radix Pseudostellariae 28-32 part, Radix Rehmanniae 28-32 part, Radix Rehmanniae Preparata 28-32 part, Fructus Corni 13-17 part, Rhizoma dioscoreae 28-32 part, Herba Epimedii 13-17 part, Semen Cuscutae 13-17 part, Radix Salviae Miltiorrhizae 28-32 part, Radix Angelicae Sinensis 13-17 part, Radix Puerariae 28-32 part, baogan medlar 28-32 part, Radix Glycyrrhizae Preparata 5-7 part.
2. be used for the treatment of the Chinese medicine composition of old-aged diabetes according to claim 1, it is characterized in that, the weight ratio of Radix Astragali, Radix Pseudostellariae, the Radix Rehmanniae and Radix Rehmanniae Preparata is 29-31:29-31:29-31:29-31.
3. according to claim 1 or 2, be used for the treatment of the Chinese medicine composition of old-aged diabetes, it is characterized in that, its raw material comprises by weight: Radix Astragali 29-31 part, Radix Pseudostellariae 29-31 part, Radix Rehmanniae 29-31 part, Radix Rehmanniae Preparata 29-31 part, Fructus Corni 14-16 part, Rhizoma dioscoreae 29-31 part, Herba Epimedii 14-16 part, Semen Cuscutae 14-16 part, Radix Salviae Miltiorrhizae 29-31 part, Radix Angelicae Sinensis 14-16 part, Radix Puerariae 29-31 part, baogan medlar 29-31 part, Radix Glycyrrhizae Preparata 5-7 part.
4. according to any one of claim 1-3, be used for the treatment of the Chinese medicine composition of old-aged diabetes, it is characterized in that, the weight ratio of Herba Epimedii, Semen Cuscutae, Radix Salviae Miltiorrhizae and Radix Angelicae Sinensis is 1:1:2:1.
5. according to any one of claim 1-4, be used for the treatment of the Chinese medicine composition of old-aged diabetes, it is characterized in that, its raw material comprises by weight: Radix Astragali 30 parts, Radix Pseudostellariae 30 parts, 30 parts, the Radix Rehmanniae, 30 parts, Radix Rehmanniae Preparata, Fructus Corni 15 parts, Rhizoma dioscoreae 30 parts, Herba Epimedii 15 parts, Semen Cuscutae 15 parts, Radix Salviae Miltiorrhizae 30 parts, Radix Angelicae Sinensis 15 parts, Radix Puerariae 30 parts, baogan medlar 30 parts, Radix Glycyrrhizae Preparata 6 parts.
6. according to claim 1-5, be used for the treatment of the Chinese medicine composition of old-aged diabetes, it is characterized in that, also comprise: Radix Ophiopogonis 6-12 part, Rhizoma Polygonati Odorati 6-12 part, Rhizoma Anemarrhenae 6-12 part.
7. according to claim 1-5, be used for the treatment of the Chinese medicine composition of old-aged diabetes, it is characterized in that, also comprise: Ramulus Cinnamomi 3-9 part, Radix Aconiti Lateralis Preparata 3-9 part, Colla cornus cervi 6-12 part.
8. according to claim 1-5, be used for the treatment of the Chinese medicine composition of old-aged diabetes, it is characterized in that, also comprise: Semen Persicae 6-9 part, Flos Carthami 3-6 part.
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| CN201510009154.1A CN104606436A (en) | 2015-01-08 | 2015-01-08 | Traditional Chinese medicine composition for treating senility diabetes mellitus |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106728879A (en) * | 2017-03-16 | 2017-05-31 | 于建红 | It is a kind of to treat new medicine composition of Department of Aged diabetes and preparation method thereof |
| CN111603535A (en) * | 2020-06-19 | 2020-09-01 | 陈绪春 | A Chinese medicinal composition for treating diabetes |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102885975A (en) * | 2012-11-05 | 2013-01-23 | 杨献华 | Traditional Chinese medicine composition for treating diabetes mellitus |
| CN104208420A (en) * | 2014-09-05 | 2014-12-17 | 苏赵珍 | Traditional Chinese medicine for treating diabetes mellitus |
-
2015
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102885975A (en) * | 2012-11-05 | 2013-01-23 | 杨献华 | Traditional Chinese medicine composition for treating diabetes mellitus |
| CN104208420A (en) * | 2014-09-05 | 2014-12-17 | 苏赵珍 | Traditional Chinese medicine for treating diabetes mellitus |
Non-Patent Citations (1)
| Title |
|---|
| 顾小侠: "补肾祛癖治疗老年性糖尿病(II型) 探究", 《中国乡村医生杂志》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106728879A (en) * | 2017-03-16 | 2017-05-31 | 于建红 | It is a kind of to treat new medicine composition of Department of Aged diabetes and preparation method thereof |
| CN111603535A (en) * | 2020-06-19 | 2020-09-01 | 陈绪春 | A Chinese medicinal composition for treating diabetes |
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