CN104604876B - A kind of brominated worm Benzoylamide and the Pesticidal combination of bishydrazide - Google Patents
A kind of brominated worm Benzoylamide and the Pesticidal combination of bishydrazide Download PDFInfo
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- CN104604876B CN104604876B CN201510057807.3A CN201510057807A CN104604876B CN 104604876 B CN104604876 B CN 104604876B CN 201510057807 A CN201510057807 A CN 201510057807A CN 104604876 B CN104604876 B CN 104604876B
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- tebufenozide
- benzoylamide
- worm benzoylamide
- bromine worm
- bromine
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Abstract
The invention discloses the Pesticidal combination of a kind of brominated worm Benzoylamide and bishydrazide, Pesticidal combination containing active components A Yu active component B, active components A is selected from bromine worm Benzoylamide, active component B is selected from any one compound following: tebufenozide, methoxyfenozide, furan tebufenozide, ring tebufenozide, chlorine tebufenozide, and the weight ratio of active components A and active component B is 1: 80～60: 1.The present composition has potentiation to the various pests of harm agricultural production, decreases pesticide usage amount, reduces pesticide residual quantity on crop, alleviate environmental pollution, and to person poultry safety, Environmental compatibility is good, and insect is not likely to produce Drug resistance.
Description
The application is divisional application, and original application is a patent that Shaanxi Meibang Pesticide Co., Ltd. submits to, Application No.
" 201210229639.8 ", apply for entitled " a kind of brominated worm Benzoylamide and the Pesticidal combination of bishydrazide ", the applying date
For 2012.07.04.
Technical field
The invention belongs to technical field of pesticide, the Pesticidal combination relating to a kind of brominated worm Benzoylamide and bishydrazide exists
Application on crop pests.
Background technology
Bishydrazide insect growth regulator, IGR is that the class developed the most successively is efficient, selectivity is strong, environmentally friendly
Insect growth regulator, IGR, its action target, as insect moulting hormones (20E), is incorporated into ecdysone receptor (EcR)
The heterodimer of superfluous valve albumen (USP), transcribing of induction insecticide early gene, but owing to bishydrazide compounds is elder brother
Sustainable existence in polypide, in the case of making 20E not exist, event can not be carried out, such as genes such as DOPA decarboxylase (DDC)
Expression be obstructed, do not synthesize chitin, eclosion hormo can not discharge, finally make larva precocity decortication and dead.
But, in the real process of agricultural production, pest control is easiest to generate the problem that the product of pest resistance to insecticide
Raw.Different cultivars composition compounds, and is to prevent and treat the method that resistant insect is the most common.Heterogeneity compounds, according to reality
Application effect, judge certain compounding be potentiation, add and or antagonism.In most cases, the compounding effect of pesticide
Be all additive effect, really have potentiation to lack, especially potentiation clearly, the highest compounding the most less of co-toxicity coefficient
?.Compounding through inventor is studied very much, find by bromine worm Benzoylamide and tebufenozide, methoxyfenozide, furan tebufenozide,
Good potentiation can be produced after ring tebufenozide, chlorine tebufenozide are compounding, and about bromine worm Benzoylamide and tebufenozide, methoxy
The relevant report that tebufenozide, furan tebufenozide, ring tebufenozide, chlorine tebufenozide compound is the openest.
Summary of the invention
The purpose of the present invention is to propose to the brominated worm Benzoylamide that there is synergistic function, use cost is low, preventive effect is good
Pesticidal combination with bishydrazide.
A kind of brominated worm Benzoylamide and the Pesticidal combination of bishydrazide, containing active components A and active component B, its
Being characterised by: active components A is 1 80～60 1 with the weight ratio of active component B, described active components A is selected from bromine worm benzene first
Amide, active component B plants selected from one of tebufenozide, methoxyfenozide, furan tebufenozide, ring tebufenozide, chlorine tebufenozide, activity
Composition A and the preferred weight ratio of active component B are 1 60～40 1, more preferably bromine worm Benzoylamide and the weight ratio of tebufenozide
Being 1 40～5 1, bromine worm Benzoylamide is 1 30～10 1 with the weight ratio of methoxyfenozide, bromine worm Benzoylamide and furan worm
The weight ratio of hydrazides is 1 30～5 1, and bromine worm Benzoylamide is 1 30～10 1 with the weight ratio of ring tebufenozide, bromine worm benzoyl
Amine is 1 30～5 1 with the weight ratio of chlorine tebufenozide；Most preferably the weight ratio of bromine worm Benzoylamide and tebufenozide be 1 30～
11, bromine worm Benzoylamide is 1 15～5 1 with the weight ratio of methoxyfenozide, bromine worm Benzoylamide and the weight of furan tebufenozide
Amount ratio is 1 20～1 1, and bromine worm Benzoylamide is 1 15～5 1 with the weight ratio of ring tebufenozide, bromine worm Benzoylamide and chlorine worm
The weight ratio of hydrazides is 1 20～1 1.
Described brominated worm Benzoylamide is used for preventing and treating the application of crop pests, institute with the Pesticidal combination of bishydrazide
The crops stated include cereal crops, legume crop, fibre crops, sugar crop, melon crop, fruits crop, dry fruit
Crop, hobby crop, root crop, oil crop, flower crop, medicinal crop, crop, green manure pasture crop；Institute
The insect stated includes striped rice borer, yellow rice borer, rice leaf roller, aleyrodid, leaf miner, beet armyworm, diamondback moth, Pieris rapae, tea chi
Earwig, heart-eating worm, leaf roller, bollworm, caterpillar, Prodenia litura, apple leaf miner.
Active components A, the weight ratio of active component B are 1 80～60 1.The generally weight hundred of active component in compositions
Dividing content is the 0.5%～90% of gross weight, is preferably 5%～80%.According to different preparation types, active component content
Scope is different.Generally, liquid preparation contains the active substance of by weight 1%～70%, preferably 5%～50%；
Solid preparation contains the active substance of by weight 5%～80%, preferably 10%～80%.
At least containing a kind of surfactant in the Pesticidal combination of the present invention, when being beneficial to use, active component is in water
Dispersion.Surface-active contents is the 5%～30% of total formulation weight amount, and surplus is solid or liquid diluent.
Surfactant selected by the Pesticidal combination of the present invention is known in those skilled in the art: can be selected from
One or more in dispersant, wetting agent, binding agent or defoamer.According to different dosage form, preparation can also contain capable
Disintegrating agent well known to field technique personnel, antifreeze etc..
The Pesticidal combination of the present invention through dilution or directly can be used before use by user.Its preparation can be by generally
Processing method known in those skilled in the art prepare, will after active substance mixes with liquid flux or solid carrier,
Add one or more in surfactant such as dispersant, stabilizer, wetting agent, binding agent, defoamer etc..
The Pesticidal combination of the present invention, can be processed into acceptable dosage form on any pesticide on demand, the most excellent dose
Type is: wettable powder, water dispersible granules, suspending agent, aqueous emulsion, microemulsion, suspension emulsion, microcapsule suspending agent, microcapsule suspension-outstanding
Floating agent.
Compositions comprises following constituent content when making wettable powder: active components A 0.5%～60%, active component
B0.5%～80%, dispersant 2%～10%, wetting agent 2%～10%, filler surplus.
Compositions includes following constituent content when making water dispersible granules: active components A 0.5%～60%, active component
B 0.5%～80%, dispersant 3%～12%, wetting agent 1%～8%, disintegrating agent 1%～10%, binding agent 0～8%, fill out
Material surplus.
Compositions includes following constituent content when making suspending agent: active components A 0.5%～50%, active component B
0.5%～50%, dispersant 2%～10%, wetting agent 2%～10%, defoamer 0.01%～2%, thickening agent 0～2%, anti-
Freeze agent 0～8%, deionized water add to 100%.
Compositions comprises following constituent content when making aqueous emulsion: active components A 0.5%～50%, active component B
0.5%～50%, solvent 1%～30%, emulsifying agent 1%～15%, antifreeze 0～8%, thickening agent 0～2%, defoamer
0.01%～2%, deionized water adds to 100%.
Compositions comprises following constituent content when making microemulsion: active components A 0.5%～50%, active component B
0.5%～50%, solvent 1%～20%, emulsifying agent 3%～25%, antifreeze 0～8%, defoamer 0.01%～2%, go from
Sub-water adds to 100%.
Compositions includes following constituent content when making suspension emulsion: active components A 0.5%～50%, active component B
0.5%～50%, dispersant 2%～10%, defoamer 0.01%～2%, solvent 1%～15%, thickening agent 0～2%, emulsifying
Agent 2%～12%, antifreeze 0～8%, deionized water add to 100%.
Compositions includes following constituent content when making microcapsule suspending agent: active components A 0.5%～50%, active component
B 0.5%～50%, macromolecule cyst material 2%～10%, dispersant 1%～10%, solvent 1%～10%, emulsifying agent 1%
～7%, defoamer 0.01%～2%, pH adjusting agent 0.01%～5%, deionized water add to 100%.
Compositions includes following constituent content when making microcapsule suspension-suspendinagent agent: active components A 0.5%～50%, live
Property composition B 0.5%～50%, macromolecule cyst material 2%～12%, dispersant 1%～12%, wetting agent 1%～8%, molten
Agent 1%～15%, emulsifying agent 1%～6%, defoamer 0.01%～2%, thickening agent 0～2%, pH adjusting agent 0.01%～
5%, deionized water adds to 100%.
The wettable powder the key technical indexes of the present invention:
The water dispersible granules the key technical indexes of the present invention:
The suspending agent the key technical indexes of the present invention:
The aqueous emulsion the key technical indexes of the present invention:
The microemulsion the key technical indexes of the present invention:
The suspension emulsion the key technical indexes of the present invention:
The microcapsule suspending agent the key technical indexes of the present invention:
The microcapsule suspension-suspendinagent agent the key technical indexes of the present invention:
It is an advantage of the current invention that:
(1) bromine worm Benzoylamide compounds with tebufenozide, methoxyfenozide, furan tebufenozide, ring tebufenozide, chlorine tebufenozide
After, there is obvious potentiation and lasting effect；(2) to cereal crops, legume crop, fibre crops, sugar crop, melon work
Thing, fruits crop, dry fruit crop, hobby crop, root crop, oil crop, flower crop, medicinal crop, raw material
Crop, the striped rice borer of green manure pasture crop, yellow rice borer, rice leaf roller, aleyrodid, leaf miner, beet armyworm, diamondback moth, dark greyish green
Worm, tea geometrid, heart-eating worm, leaf roller, bollworm, caterpillar, Prodenia litura, apple leaf miner etc. all have greater activity；(3) decrease
Pesticide usage amount, reduces pesticide residual quantity on crop, alleviates environmental pollution；(4) to person poultry safety, Environmental compatibility
Good, and the enhancing of preparation adhesion strength, resistance of rainwater washing against.
Detailed description of the invention
Below in conjunction with embodiment, further instruction of the present invention, the percentage ratio in embodiment are all weight percentage, but
The invention is not limited in this.
Application Example one
Example 1～16 wettable powder
By bromine worm Benzoylamide, active component B, dispersant, wetting agent, filler mix homogeneously in mixed cylinder, through air-flow
Pulverizer remixes uniformly after pulverizing, and can be prepared by wettable powder product of the present invention, is specifically shown in Table 1,2,3.
Table 1 example 1～5 component and content
Table 2 example 6～10 component and content
Table 3 example 11～16 component and content
Example 17～32 water dispersible granules
Bromine worm Benzoylamide, active component B, dispersant, wetting agent, disintegrating agent, filler etc. are obtained through comminution by gas stream together
To the particle diameter needed, add other auxiliary agents such as binding agent (can add and can be not added with), obtain granulation materials.Item is quantitatively sent into stream
Through in changing bed granulating drier and granulation and dried, can be prepared by water dispersible granules product of the present invention, be specifically shown in Table
4、5、6。
Table 4 example 17～21 component and content
Table 5 example 22～26 component and content
Table 6 example 27～32 component and content
Example 33～48 suspending agent
By dispersant, wetting agent, defoamer, thickening agent (can add and can be not added with), antifreeze (can add and can be not added with), through at a high speed
Shear-mixed is uniform, adds bromine worm Benzoylamide, active component B, ball milling 2～3 hours in ball mill, makes diameter of particle whole
Below 5 μm, surplus deionized water is supplied, and can be prepared by suspending agent product of the present invention, is specifically shown in Table 7,8,9.
Table 7 example 33～37 component and content
Table 8 example 38～42 component and content
Table 9 example 43～48 component and content
Example 49～56 aqueous emulsion
Bromine worm Benzoylamide, active component B, solvent, emulsifying agent are added together, make to be dissolved into homogeneous oil phase；To go from
Sub-water, antifreeze (can add and can be not added with), thickening agent (can add and can be not added with), defoamer mix, and become homogeneous aqueous phase.At a high speed
Under stirring, aqueous phase adding oil phase, surplus deionized water is supplied；Can be prepared by aqueous emulsion product of the present invention, specifically
It is shown in Table 10,11.
Table 10 example 49～52 component and content
Table 11 example 53～56 component and content
Example 57～64 microemulsion
Bromine worm Benzoylamide, active component B are dissolved in equipped with in the homogenizer of solvent, emulsifying agent, antifreeze (can be added
Can be not added with), defoamer join in the homogenizer equipped with above-mentioned solution, surplus deionized water mixes also after supplying strongly
Homogenize, finally obtain the microemulsion product of the present invention that clear appearance is transparent.Specifically it is shown in Table 12,13.
Table 12 example 57～60 component and content
Table 13 example 61～64 component and content
Example 65～72 suspension emulsion
Dispersant, defoamer, thickening agent (can add and can be not added with), antifreeze (can add and can be not added with) are mixed through high speed shear
Uniformly, add bromine worm Benzoylamide, ball milling 2～3 hours in ball mill, make diameter of particle all below 5 μm, prepare bromine worm
Benzoylamide suspending agent, then by active component B, emulsifying agent, solvent and the various direct emulsifying of auxiliary agent high speed agitator to outstanding
In floating agent, prepare suspension emulsion product of the present invention.Specifically it is shown in Table 14,15.
Table 14 example 65～68 component and content
Table 15 example 69～72 component and content
Tebufenozide, methoxyfenozide, furan tebufenozide, ring tebufenozide, chlorine tebufenozide in table 1～15 are exchanged, can prepare
Novel formulation.
Example 73～75 microcapsule suspending agent
By bromine worm Benzoylamide, active component B, macromolecule cyst material, solvent mixing, make to be dissolved into homogeneous oil phase,
Under shearing condition, oil phase is joined containing emulsifying agent, pH adjusting agent, dispersant, defoamer aqueous phase solution in, surplus spends
Ionized water is supplied, and bi-material reacts at oil-water interfaces, forms macromolecule cyst wall, makes present composition good dispersion
Microcapsule suspending agent product, be specifically shown in Table 16.
Table 16 example 73～75 component and content
Example 76～78 microcapsule suspension-suspendinagent agent
By active component B, macromolecule cyst material, solvent mixing, make to be dissolved into homogeneous oil phase, by oil phase at shearing condition
Under join containing emulsifying agent, pH adjusting agent aqueous phase solution in, make finely disseminated microcapsule suspending agent.By defoamer, increasing
Thick dose (can add and can be not added with) through high speed shear mix homogeneously, adds bromine worm Benzoylamide, ball milling 2～3 hours in ball mill,
Make diameter of particle all below 5 μm, prepare suspending agent, then suspending agent is joined the aqueous phase solution of micro-capsule suspension
In, deionized water supplies surplus, makes the present composition finely disseminated microcapsule suspension-suspendinagent agent product, is specifically shown in Table 17.
Table 17 embodiment 76～78 each component and weight portion
The embodiment of the present invention is the method using Toxicity Determination and field test to combine.First pass through indoor virulence to survey
Fixed, after clear and definite two kinds of medicaments are compounding by a certain percentage co-toxicity coefficient (CTC), CTC ＜ 80 is antagonism, 80≤CTC≤120
For summation action, CTC ＞ 120 is potentiation, on this basis, then carries out field test.
Test method: respectively the mother solution of each mixed agent is diluted to during test five series concentration, is respectively placed in beaker
Standby.Use the method that first leaching leaf is followed by worm, by the blade of the same size not in contact with any medicament in the medicinal liquid configured
Take out after soaking 5s, naturally dry, put in insect box, then connect for examination larva, raise under the conditions of 25 DEG C, often process 3
Secondary repetition, often repeating examination borer population used is 50, sets blank simultaneously, checks dead borer population in 72h, calculates mortality rate and correction
Mortality rate, tries to achieve virulence regression equation and calculates LC50Value.If comparison mortality rate is more than 10%, then it is considered as invalid test.Calculate public affairs
Formula is as follows:
Insect corrected mortality is converted into probit value (y), and concentration for the treatment of (μ g/ml) is converted into logarithm value (x), with minimum
Square law draws virulence regression equation, and thus calculates the value of every kind of medicament.Common poison system is calculated according to the abundant equation of Sun Yun
Number CTC.Computing formula is following (with bromine worm Benzoylamide as standard agent, its toxicity index is 100):
TI × the P of the theoretical toxicity index (TTI) of M=bromine worm BenzoylamideBromine worm BenzoylamideThe TI of+effective active composition B ×
PEffective active composition B
In formula: M is the mixture of different ratio
PEffective active composition BFor the ratio that effective active composition B is shared in the composition
PBromine worm BenzoylamideFor the ratio that bromine worm Benzoylamide is shared in the composition
B plants selected from one of tebufenozide, methoxyfenozide, furan tebufenozide, ring tebufenozide, chlorine tebufenozide.
Application Example two:
For examination insect: Laphygma exigua Hubner
Test medicine is provided by Shaanxi Meibang Pesticide Co., Ltd..
EXPERIMENTAL DESIGN: determine bromine worm Benzoylamide and the former medicine of tebufenozide and the two different ratio mixture through pilot study
Effectively lethasl concentration scope.
Toxicity test result
Table 18 bromine worm Benzoylamide toxicity test analysis of results table to Laphygma exigua Hubner compounding with tebufenozide
| Reagent agent | Proportioning | LC50(ug/mL) | Co-toxicity coefficient (CTC) |
| Bromine worm Benzoylamide | — | 0.63 | — |
| Tebufenozide | — | 8.72 | — |
| Bromine worm Benzoylamide tebufenozide | 1:80 | 2.37 | 193.27 |
| Bromine worm Benzoylamide tebufenozide | 1:60 | 2.15 | 207.71 |
| Bromine worm Benzoylamide tebufenozide | 1:40 | 1.91 | 222.78 |
| Bromine worm Benzoylamide tebufenozide | 1:20 | 1.58 | 236.86 |
| Bromine worm Benzoylamide tebufenozide | 1:10 | 1.23 | 248.46 |
| Bromine worm Benzoylamide tebufenozide | 1:8 | 1.09 | 258.27 |
| Bromine worm Benzoylamide tebufenozide | 1:5 | 0.93 | 248.78 |
| Bromine worm Benzoylamide tebufenozide | 1:1 | 0.47 | 237.93 |
| Bromine worm Benzoylamide tebufenozide | 5:1 | 0.33 | 223.43 |
| Bromine worm Benzoylamide tebufenozide | 15:1 | 0.31 | 214.96 |
| Bromine worm Benzoylamide tebufenozide | 30:1 | 0.32 | 202.58 |
| Bromine worm Benzoylamide tebufenozide | 40:1 | 0.34 | 189.33 |
| Bromine worm Benzoylamide tebufenozide | 60:1 | 0.36 | 177.54 |
As shown in Table 18, bromine worm Benzoylamide and tebufenozide compound the proportioning of preventing and treating Laphygma exigua Hubner 1 80～60 1
Time, co-toxicity coefficient is all higher than 120, illustrates that both all show potentiation, when bromine worm benzene at mixture in the range of 1 80～60 1
The proportioning of Methanamide and tebufenozide is when 1 40～5 1, and potentiation is the most prominent, and co-toxicity coefficient is all higher than 220, through applicant
Test find the optimum ratio of bromine worm Benzoylamide and tebufenozide be 5:1,1:1,1:5,1:6,1:7,1:8,1:9,1:10,1:
11,1:12,1:13,1:14,1:15,1:16,1:17,1:18,1:19,1:20,1:21,1:22,1:23,1:24,1:25,1:
30,1,1:35,1:40, wherein when bromine worm Benzoylamide and tebufenozide weight ratio are 18, co-toxicity coefficient is maximum, and potentiation is
For substantially.
Application Example three
For examination insect: rice-stem borer
Test medicine is provided by Shaanxi Meibang Pesticide Co., Ltd..
EXPERIMENTAL DESIGN: determine that bromine worm Benzoylamide mixes with the former medicine of methoxyfenozide and the two different ratio through pilot study
Effective lethasl concentration scope of agent.
Table 19 bromine worm Benzoylamide toxicity test analysis of results table to rice-stem borer compounding with methoxyfenozide
| Reagent agent | Proportioning | LC50(ug/mL) | Co-toxicity coefficient (CTC) |
| Bromine worm Benzoylamide | — | 0.57 | — |
| Methoxyfenozide | — | 1.63 | — |
| Bromine worm Benzoylamide methoxyfenozide | 1:80 | 0.87 | 183.15 |
| Bromine worm Benzoylamide methoxyfenozide | 1:60 | 0.80 | 197.72 |
| Bromine worm Benzoylamide methoxyfenozide | 1:40 | 0.74 | 210.71 |
| Bromine worm Benzoylamide methoxyfenozide | 1:30 | 0.69 | 222.86 |
| Bromine worm Benzoylamide methoxyfenozide | 1:15 | 0.63 | 231.79 |
| Bromine worm Benzoylamide methoxyfenozide | 1:5 | 0.52 | 239.29 |
| Bromine worm Benzoylamide methoxyfenozide | 1:3 | 0.45 | 247.27 |
| Bromine worm Benzoylamide methoxyfenozide | 1:1 | 0.35 | 241.32 |
| Bromine worm Benzoylamide methoxyfenozide | 5:1 | 0.27 | 236.77 |
| Bromine worm Benzoylamide methoxyfenozide | 10:1 | 0.27 | 224.38 |
| Bromine worm Benzoylamide methoxyfenozide | 20:1 | 0.28 | 210.08 |
| Bromine worm Benzoylamide methoxyfenozide | 40:1 | 0.29 | 199.72 |
| Bromine worm Benzoylamide methoxyfenozide | 60:1 | 0.31 | 185.85 |
As shown in Table 19, bromine worm Benzoylamide and methoxyfenozide compound the proportioning of preventing and treating rice-stem borer 1 80～
When 60 1, co-toxicity coefficient is all higher than 120, illustrates that both all show potentiation at mixture in the range of 1 80～60 1, works as bromine
The proportioning of worm Benzoylamide and methoxyfenozide is when 1 30～10 1, and potentiation is the most prominent, and co-toxicity coefficient is all higher than
220, through applicant test find the optimum ratio of bromine worm Benzoylamide and methoxyfenozide be 10:1,5:1,1:1,1:5,1:6,
1:7,1:8,1:9,1:10,1:11,1:12,1:13,1:14,1:15,1:16,1:17,1:18,1:19,1:20,1:21,1:22,
1:23,1:24,1:25,1:30, wherein when bromine worm Benzoylamide and methoxyfenozide weight ratio are 13, co-toxicity coefficient is maximum,
Potentiation is the most obvious.
Application Example four
For examination insect: brassicaceous vegetable diamondback moth
Test medicine is provided by Shaanxi Meibang Pesticide Co., Ltd..
EXPERIMENTAL DESIGN: determine that bromine worm Benzoylamide mixes with the former medicine of furan tebufenozide and the two different ratio through pilot study
Effective lethasl concentration scope of agent
Table 20 bromine worm Benzoylamide toxicity test result to brassicaceous vegetable diamondback moth compounding with furan tebufenozide is divided
Analysis table
| Reagent agent | Proportioning | LC50(ug/mL) | Co-toxicity coefficient (CTC) |
| Bromine worm Benzoylamide | — | 0.71 | — |
| Furan tebufenozide | — | 4.96 | — |
| Bromine worm Benzoylamide furan tebufenozide | 1:80 | 2.46 | 187.75 |
| Bromine worm Benzoylamide furan tebufenozide | 1:60 | 2.22 | 203.46 |
| Bromine worm Benzoylamide furan tebufenozide | 1:40 | 1.99 | 217.49 |
| Bromine worm Benzoylamide furan tebufenozide | 1:30 | 1.80 | 230.96 |
| Bromine worm Benzoylamide furan tebufenozide | 1:20 | 1.59 | 242.75 |
| Bromine worm Benzoylamide furan tebufenozide | 1:10 | 1.26 | 254.93 |
| Bromine worm Benzoylamide furan tebufenozide | 1:7 | 1.08 | 262.70 |
| Bromine worm Benzoylamide furan tebufenozide | 1:5 | 0.97 | 255.97 |
| Bromine worm Benzoylamide furan tebufenozide | 1:1 | 0.50 | 248.44 |
| Bromine worm Benzoylamide furan tebufenozide | 5:1 | 0.35 | 236.65 |
| Bromine worm Benzoylamide furan tebufenozide | 15:1 | 0.35 | 214.34 |
| Bromine worm Benzoylamide furan tebufenozide | 30:1 | 0.36 | 202.83 |
| Bromine worm Benzoylamide furan tebufenozide | 40:1 | 0.38 | 190.83 |
| Bromine worm Benzoylamide furan tebufenozide | 60:1 | 0.40 | 180.03 |
As shown in Table 20, bromine worm Benzoylamide and furan tebufenozide compound the proportioning of preventing and treating brassicaceous vegetable diamondback moth and exist
When 1 80～60 1, co-toxicity coefficient is all higher than 120, illustrates that both mixtures in the range of 1 80～60 1 all show potentiation and make
With, when the proportioning of bromine worm Benzoylamide and furan tebufenozide is in 1 30～5 1, potentiation is the most prominent, and co-toxicity coefficient is equal
More than 230, through applicant test find the optimum ratio of bromine worm Benzoylamide and furan tebufenozide be 5:1,1:1,1:5,1:6,
1:7,1:8,1:9,1:10,1:11,1:12,1:13,1:14,1:15,1:16,1:17,1:18,1:19,1:20,1:21,1:22,
1:23,1:24,1:25,1:30, wherein when bromine worm Benzoylamide and furan tebufenozide weight ratio are 17, co-toxicity coefficient is maximum,
Potentiation is the most obvious.
Application Example five
For examination insect: Fructus Mali pumilae small heart-eating peach worm
Test medicine is provided by Shaanxi Meibang Pesticide Co., Ltd..
EXPERIMENTAL DESIGN: determine bromine worm Benzoylamide and the former medicine of ring tebufenozide and the two different ratio mixture through pilot study
Effective lethasl concentration scope.
Table 21 bromine worm Benzoylamide toxicity test analysis of results table to Fructus Mali pumilae small heart-eating peach worm compounding with ring tebufenozide
| Reagent agent | Proportioning | LC50(ug/mL) | Co-toxicity coefficient (CTC) |
| Bromine worm Benzoylamide | — | 0.62 | — |
| Ring tebufenozide | — | 1.83 | — |
| Bromine worm Benzoylamide ring tebufenozide | 1:80 | 0.97 | 184.22 |
| Bromine worm Benzoylamide ring tebufenozide | 1:60 | 0.90 | 197.03 |
| Bromine worm Benzoylamide ring tebufenozide | 1:40 | 0.83 | 210.46 |
| Bromine worm Benzoylamide ring tebufenozide | 1:30 | 0.77 | 223.59 |
| Bromine worm Benzoylamide ring tebufenozide | 1:15 | 0.70 | 233.01 |
| Bromine worm Benzoylamide ring tebufenozide | 1:5 | 0.56 | 246.58 |
| Bromine worm Benzoylamide ring tebufenozide | 1:3 | 0.48 | 256.23 |
| Bromine worm Benzoylamide ring tebufenozide | 1:1 | 0.37 | 250.33 |
| Bromine worm Benzoylamide ring tebufenozide | 5:1 | 0.29 | 240.27 |
| Bromine worm Benzoylamide ring tebufenozide | 10:1 | 0.29 | 227.47 |
| Bromine worm Benzoylamide ring tebufenozide | 20:1 | 0.30 | 213.39 |
| Bromine worm Benzoylamide ring tebufenozide | 40:1 | 0.31 | 203.28 |
| Bromine worm Benzoylamide ring tebufenozide | 60:1 | 0.34 | 184.35 |
As shown in Table 21, bromine worm Benzoylamide and ring tebufenozide compound the proportioning of preventing and treating Fructus Mali pumilae small heart-eating peach worm 1 80～
When 60 1, co-toxicity coefficient is all higher than 120, illustrates that both all show potentiation at mixture in the range of 1 80～60 1, works as bromine
The proportioning of worm Benzoylamide and ring tebufenozide is when 1 30～10 1, and potentiation is the most prominent, and co-toxicity coefficient is all higher than 220,
Through applicant test find the optimum ratio of bromine worm Benzoylamide and ring tebufenozide be 10:1,5:1,1:1,1:5,1:6,1:7,1:
8,1:9,1:10,1:11,1:12,1:13,1:14,1:15,1:16,1:17,1:18,1:19,1:20,1:21,1:22,1:23,
1:24,1:25,1:30, wherein when bromine worm Benzoylamide and ring tebufenozide weight ratio are 13, co-toxicity coefficient is maximum, potentiation
The most obvious.
Application Example six
For examination insect: cotton boll worm
Test medicine is provided by Shaanxi Meibang Pesticide Co., Ltd..
EXPERIMENTAL DESIGN: determine bromine worm Benzoylamide and the former medicine of chlorine tebufenozide and the two different ratio mixture through pilot study
Effective lethasl concentration scope
Table 22 bromine worm Benzoylamide toxicity test analysis of results table to cotton boll worm compounding with chlorine tebufenozide
| Reagent agent | Proportioning | LC50(ug/mL) | Co-toxicity coefficient (CTC) |
| Bromine worm Benzoylamide | — | 0.73 | — |
| Chlorine tebufenozide | — | 4.36 | — |
| Bromine worm Benzoylamide chlorine tebufenozide | 1:80 | 2.17 | 189.30 |
| Bromine worm Benzoylamide chlorine tebufenozide | 1:60 | 1.97 | 204.64 |
| Bromine worm Benzoylamide chlorine tebufenozide | 1:40 | 1.78 | 218.45 |
| Bromine worm Benzoylamide chlorine tebufenozide | 1:30 | 1.62 | 231.93 |
| Bromine worm Benzoylamide chlorine tebufenozide | 1:20 | 1.46 | 241.46 |
| Bromine worm Benzoylamide chlorine tebufenozide | 1:10 | 1.20 | 250.22 |
| Bromine worm Benzoylamide chlorine tebufenozide | 1:6 | 0.98 | 260.12 |
| Bromine worm Benzoylamide chlorine tebufenozide | 1:5 | 0.94 | 253.63 |
| Bromine worm Benzoylamide chlorine tebufenozide | 1:1 | 0.51 | 245.22 |
| Bromine worm Benzoylamide chlorine tebufenozide | 5:1 | 0.36 | 235.45 |
| Bromine worm Benzoylamide chlorine tebufenozide | 15:1 | 0.35 | 220.02 |
| Bromine worm Benzoylamide chlorine tebufenozide | 30:1 | 0.36 | 208.37 |
| Bromine worm Benzoylamide chlorine tebufenozide | 40:1 | 0.38 | 196.09 |
| Bromine worm Benzoylamide chlorine tebufenozide | 60:1 | 0.41 | 180.51 |
As shown in Table 22, bromine worm Benzoylamide and chlorine tebufenozide compound the proportioning of preventing and treating cotton boll worm 1 80～60 1
Time, co-toxicity coefficient is all higher than 120, illustrates that both all show potentiation, when bromine worm benzene at mixture in the range of 1 80～60 1
The proportioning of Methanamide and chlorine tebufenozide is when 1 30～5 1, and potentiation is the most prominent, and co-toxicity coefficient is all higher than 230, through application
People test find the optimum ratio of bromine worm Benzoylamide and chlorine tebufenozide be 5:1,1:1,1:5,1:6,1:7,1:8,1:9,1:10,
1:11,1:12,1:13,1:14,1:15,1:16,1:17,1:18,1:19,1:20,1:21,1:22,1:23,1:24,1:25,1:
30, wherein when bromine worm Benzoylamide and chlorine tebufenozide weight ratio are 16, co-toxicity coefficient is maximum, and potentiation is the most obvious.
Find through test: after bromine worm Benzoylamide and active component B are compounding to the striped rice borer in various crop, yellow rice borer,
Rice leaf roller, aleyrodid, leaf miner, beet armyworm, diamondback moth, Pieris rapae, tea geometrid, heart-eating worm, leaf roller, bollworm, hair
Worm, Prodenia litura, the preventing and treating of apple leaf miner have obvious potentiation, and co-toxicity coefficient is all more than 120.
Test of pesticide effectiveness part test medicament is researched and developed by Shaanxi Meibang Pesticide Co., Ltd., is provided, and compares medicament 10% bromine
Worm Benzoylamide suspending agent (autogamy), 10% Tebufenozide suspending agent (commercial), 240g/L methoxyfenozide suspending agent (commercial),
10% furan tebufenozide suspending agent (commercial), 10% chromafenozide suspending agent (autogamy), 10% chlorine Tebufenozide suspending agent (autogamy).
Application Example seven bromine worm Benzoylamide and active component B and the compounding preventing and treating Laphygma exigua Hubner test of pesticide effectiveness thereof
This test arrangement, at Xian District, Shanxi Province suburban area, is investigated Laphygma exigua Hubner insect pest index, is occurred in insect pest before medicine
Initial stage dispenser, investigates insect pest indexes and calculates preventive effect for after dispenser 3 days, 7 days, 15 days.Result of the test is as follows:
Table 23 bromine worm Benzoylamide and active component B and the compounding preventing and treating Laphygma exigua Hubner test of pesticide effectiveness thereof
As can be seen from Table 23, after bromine worm Benzoylamide is compounding with active component B, can effectively prevent and treat Laphygma exigua Hubner, anti-
Control effect and be superior to the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example eight bromine worm Benzoylamide and active component B and the compounding preventing and treating rice-stem borer test of pesticide effectiveness thereof
This test arrangement, at Shaanxi Province's Hanzhong City, is investigated rice-stem borer insect pest index, is executed at insect pest early period of origination before medicine
Medicine, investigates insect pest indexes and calculates preventive effect for after dispenser 10 days, 20 days, 30 days.Result of the test is as follows:
Table 24 bromine worm Benzoylamide and active component B and the compounding preventing and treating rice-stem borer test of pesticide effectiveness thereof
As can be seen from Table 24, rice-stem borer can effectively be prevented and treated after bromine worm Benzoylamide is compounding with active component B, preventing and treating
Effect is superior to the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example nine bromine worm Benzoylamide and active component B and the compounding preventing and treating phyllocnistis citrella stainton test of pesticide effectiveness thereof
This test arrangement, at Shaanxi Province's Hanzhong City, is investigated phyllocnistis citrella stainton insect pest index, is executed at insect pest early period of origination before medicine
Medicine, investigates insect pest indexes and calculates preventive effect for after dispenser 3 days, 7 days, 15 days.Result of the test is as follows:
Table 25 bromine worm Benzoylamide and active component B and the compounding preventing and treating phyllocnistis citrella stainton test of pesticide effectiveness thereof
As can be seen from Table 25, phyllocnistis citrella stainton can effectively be prevented and treated after bromine worm Benzoylamide is compounding with active component B, preventing and treating
Effect is superior to the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example ten bromine worm Benzoylamide and active component B and the compounding preventing and treating cotton boll worm test of pesticide effectiveness thereof
This test arrangement, in Dali County, Shaanxi Province, is investigated cotton boll pests index, is executed at insect pest early period of origination before medicine
Medicine, investigates insect pest indexes and calculates preventive effect for after dispenser 3 days, 7 days, 15 days.Result of the test is as follows:
Table 26 bromine worm Benzoylamide and active component B and the compounding preventing and treating cotton boll worm test of pesticide effectiveness thereof
As can be seen from Table 26, cotton boll worm can effectively be prevented and treated after bromine worm Benzoylamide is compounding with active component B, preventing and treating
Effect is superior to the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example ten monobromo worm Benzoylamide and active component B and the compounding preventing and treating cabbage pieris test of pesticide effectiveness thereof
This test arrangement, at Xian District, Shanxi Province suburban area, investigates cabbage pieris insect pest index, at the beginning of insect pest occurs before medicine
Phase dispenser, investigates insect pest indexes and calculates preventive effect for after dispenser 3 days, 7 days, 15 days.Result of the test is as follows:
Table 27 bromine worm Benzoylamide and active component B and the compounding preventing and treating cabbage pieris test of pesticide effectiveness thereof
As can be seen from Table 27, cabbage pieris can effectively be prevented and treated after bromine worm Benzoylamide is compounding with active component B, preventing and treating
Effect is superior to the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example ten dibromo worm Benzoylamide and active component B and compounding preventing and treating Fructus Mali pumilae small heart-eating peach worm drug effect thereof
Test
This test arrangement, at Shaanxi Province's Weinan City, investigates Fructus Mali pumilae small heart-eating peach worm insect pest index, at the beginning of insect pest occurs before medicine
Phase dispenser, investigates insect pest indexes and calculates preventive effect for after dispenser 10 days, 20 days, 30 days.Result of the test is as follows:
Table 28 bromine worm Benzoylamide and active component B and the compounding preventing and treating Fructus Mali pumilae small heart-eating peach worm test of pesticide effectiveness thereof
As can be seen from Table 28, after bromine worm Benzoylamide is compounding with active component B, can effectively prevent and treat Fructus Mali pumilae small heart-eating peach worm,
Prevention effect is superior to the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
Application Example ten tribromo worm Benzoylamide and active component B and the compounding preventing and treating Fructus Lycopersici esculenti Bemisia tabaci test of pesticide effectiveness thereof
This test arrangement, at Xian District, Shanxi Province suburban area, investigates Fructus Lycopersici esculenti Bemisia tabaci insect pest index, at the beginning of insect pest occurs before medicine
Phase dispenser, investigates insect pest indexes and calculates preventive effect for after dispenser 3 days, 7 days, 15 days.Result of the test is as follows:
Table 29 bromine worm Benzoylamide and active component B and the compounding preventing and treating Fructus Lycopersici esculenti Bemisia tabaci test of pesticide effectiveness thereof
As can be seen from Table 29, Fructus Lycopersici esculenti Bemisia tabaci can effectively be prevented and treated after bromine worm Benzoylamide is compounding with active component B, preventing and treating
Effect is superior to the preventive effect of single dose, and the preventive effect phase is long.In test scope of medication, target crop is had no adverse effects.
After draw through tests different local throughout the country, bromine worm Benzoylamide and tebufenozide, methoxyfenozide, furan
After tebufenozide, ring tebufenozide, the chlorine tebufenozide of muttering is compounding to the striped rice borer in various crop, yellow rice borer, rice leaf roller, aleyrodid,
Leaf miner, beet armyworm, diamondback moth, Pieris rapae, tea geometrid, heart-eating worm, leaf roller, bollworm, caterpillar, Prodenia litura, Jin Wen
The preventive effect of the common insect pests such as thin moth, all more than 95%, is better than single dose preventive effect, and potentiation is obvious.
Claims (6)
1. brominated worm Benzoylamide and a Pesticidal combination for bishydrazide, effective active composition is active components A and activity
Composition B, it is characterised in that: active components A is 1 80 ~ 60 1 with the weight ratio of active component B, and described active components A is bromine
Worm Benzoylamide, active component B is furan tebufenozide.
Brominated worm Benzoylamide the most according to claim 1 and the Pesticidal combination of bishydrazide, it is characterised in that: activity
The weight ratio of composition A and active component B is 1 60 ~ 40 1.
Brominated worm Benzoylamide the most according to claim 2 and the Pesticidal combination of bishydrazide, it is characterised in that:
Bromine worm Benzoylamide is 1 30 ~ 51 with the weight ratio of furan tebufenozide.
Brominated worm Benzoylamide the most according to any one of claim 1 to 3 and the Pesticidal combination of bishydrazide, it is special
Levy and be: compositions makes wettable powder, water dispersible granules, suspending agent, aqueous emulsion, microemulsion, suspension emulsion, microcapsule suspension
Agent, microcapsule suspension-suspendinagent agent.
Brominated worm Benzoylamide the most according to claim 4 is used for preventing and treating crops with the Pesticidal combination of bishydrazide
The purposes of insect.
Purposes the most according to claim 5, it is characterised in that: described insect includes striped rice borer, yellow rice borer, cnaphalocrocis
Snout moth's larva, aleyrodid, leaf miner, beet armyworm, diamondback moth, Pieris rapae, tea geometrid, heart-eating worm, leaf roller, bollworm, caterpillar, twill night
Moth, apple leaf miner.
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| CN201210229639.8A CN103518730B (en) | 2012-07-04 | 2012-07-04 | The Pesticidal combination of a kind of brominated worm benzamide and bishydrazide |
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1988803A (en) * | 2004-07-26 | 2007-06-27 | 杜邦公司 | Mixtures of anthranilamide invertebrate pest control agents |
| CN101669488A (en) * | 2009-09-29 | 2010-03-17 | 山东京博控股发展有限公司 | Binary complex pesticide composition containing chlorantraniliprole |
| CN102113516A (en) * | 2010-01-05 | 2011-07-06 | 海南正业中农高科股份有限公司 | Insect killing compound containing chlorantraniliprole |
| CN103300000A (en) * | 2012-03-12 | 2013-09-18 | 陕西韦尔奇作物保护有限公司 | Insecticidal composition containing chromafenozide and amide |
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2012
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Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1988803A (en) * | 2004-07-26 | 2007-06-27 | 杜邦公司 | Mixtures of anthranilamide invertebrate pest control agents |
| CN101669488A (en) * | 2009-09-29 | 2010-03-17 | 山东京博控股发展有限公司 | Binary complex pesticide composition containing chlorantraniliprole |
| CN102113516A (en) * | 2010-01-05 | 2011-07-06 | 海南正业中农高科股份有限公司 | Insect killing compound containing chlorantraniliprole |
| CN103300000A (en) * | 2012-03-12 | 2013-09-18 | 陕西韦尔奇作物保护有限公司 | Insecticidal composition containing chromafenozide and amide |
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