CN104547827A - Traditional Chinese medicine for treating hypertension and application of traditional Chinese medicine - Google Patents
Traditional Chinese medicine for treating hypertension and application of traditional Chinese medicine Download PDFInfo
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- CN104547827A CN104547827A CN201510009111.3A CN201510009111A CN104547827A CN 104547827 A CN104547827 A CN 104547827A CN 201510009111 A CN201510009111 A CN 201510009111A CN 104547827 A CN104547827 A CN 104547827A
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Abstract
The invention discloses a traditional Chinese medicine for treating hypertension and belongs to the technical field of traditional Chinese medicine. The traditional Chinese medicine is prepared from such traditional Chinese medicinal materials as fruit of Chinese holly, oriental sesame seed, twig and leaf of flathshoot mistletoe, flower of intermediate peashrub, rhizome of tendrilleaf solomonseal, herb of woolyfruit stylophorum, mulberry, alectoria asiatica, standing grain worm, katsumade galangal seed, root of austral akebia, white sixangular dysosma rhizome, all-grass of bulley herminium and all-grass of sharptooth incarvillea. The traditional Chinese medicine is based on the therapeutic principles of nourishing yin and tonifying liver and kidney, tonifying spleen and invigorating stomach, invigorating spleen and eliminating dampness, promoting the circulation of qi and dispersing blood stasis, and is reasonable in formula compatibility; all the medicinal materials are adjuvant to each other to achieve the effects of nourishing yin and tonifying liver, nourishing blood and invigorating spleen and stomach, activating blood and promoting the circulation of qi, and promoting the secretion of body fluid to moisten dryness; as a result, the purpose of thoroughly treating the hypertension can be achieved.
Description
Technical field
The invention belongs to technical field of Chinese medicine, be specifically related to one and treat hypertensive medicine.
Background technology
Hypertension a kind of raises clinical syndrome for feature with body circulation systolic arterial pressure (SBP) and (or) diastolic pressure (DBP), and it is one of the most common, most important clinical cardiovascular disease at present.Along with improving constantly of people's living standard, hypertensive prevalence also increases in year, and China carries out generaI investigation preventing and controlling to hypertension from nineteen fifty-nine, and the prevalence of adult hypertension was 5.1% at that time; During to 1979-1980 second time Sampled Study of hypertension, adult hypertension prevalence (comprising borderline hypertension) is increased to 7.73%; Time national hypertension census result display of 1990-1991 third time, Prevalence of Hypertension is having again remarkable growth during the decade, estimates that the whole nation has 6,000 ten thousand hyperpietics at least at that time.According to another updated statistics, the hypertensive prevalence of current China rises to 11.68%, and especially the target organ damage such as the heart, brain, kidney of hypertension secondary, has a strong impact on life-span and the quality of life of patient, become the disease of serious threat human health and life.Current treatment hypertension takes Western medicine more, but Western medicine needs long-term taking, there is serious side effect, and can only control blood pressure, can not effect a radical cure.Chinese medicine is little relative to Western medicine side effect, but existing Chinese medicine effect when treating hypertension is undesirable.
Summary of the invention
The object of the invention is to overcome above-mentioned technical problem, a kind of safe without toxic side effect is provided, the Chinese hypotensor of Be very effective.
For achieving the above object, the present invention by the following technical solutions.
One treats hypertensive Chinese medicine, is obtained by the traditional Chinese medicinal material raw materials of following weight portion: Fructus Ilicis Cornutae 32-34 part, Semen sesami Niger 30-32 part, Li Jisheng 28-30 part, Flos Caraganae intermediae 31-33 part, Rhizoma Polygonati Cirrhifolii 38-40 part, Herba Stylophori Lasiocapi 29-31 part, Fructus Mori 27-29 part, Alectoria asiatica Du Rietz 10-12 part, Tylorrhynchus heterochaeta Quatrefages 8-10 part, Semen Alpiniae Katsumadai 11-13 part, Radix Akebiae 10-12 part, white Radix et Rhizoma Dysosmatis 7-9 part, musk orchid 9-11 part, suona horn flower 5-7 part.
Preferably, the hypertensive Chinese medicine of above-mentioned treatment, is obtained by the traditional Chinese medicinal material raw materials of following weight portion: Fructus Ilicis Cornutae 33 parts, Semen sesami Niger 31 parts, Li Jisheng 29 parts, Flos Caraganae intermediae 32 parts, Rhizoma Polygonati Cirrhifolii 39 parts, Herba Stylophori Lasiocapi 30 parts, 28 parts, Fructus Mori, Alectoria asiatica Du Rietz 11 parts, Tylorrhynchus heterochaeta Quatrefages 9 parts, Semen Alpiniae Katsumadai 12 parts, Radix Akebiae 11 parts, white Radix et Rhizoma Dysosmatis 8 parts, musk orchid 10 parts, suona horn spend 6 parts.
According to Chinese medicine Historical Data Data About, the pharmacologically active of above-mentioned Chinese crude drug and function cure mainly as follows.
Fructus Ilicis Cornutae, [nature and flavor] are bitter, puckery, tepor.[function cures mainly] YIN nourishing, benefit essence, active.Invigorating the liver and kidney; Strong muscle is active; The astringent or styptic treatment for spontaneous sweating part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels.Control deficiency of YIN fever of the body, stranguria with turbid discharge, metrorrhagia and leukorrhagia, bones and muscles pain." herbal classic is met former ": " promoting blood circulation to remove blood stasis, strong muscles and bones, fills up marrow dirty, admittedly hold back essence and blood.”
Fructus Mori, [nature and flavor] are sweet, sour, cold.[function cures mainly] to be enriched blood YIN nourishing, is promoted the production of body fluid and moisturize.For vertigo and tinnitus, palpitation and insomnia, early whitening of beard and hair, Tianjin wound is thirsty, and interior-heat is quenched one's thirst, blood deficiency and constipation.
Semen sesami Niger, [nature and flavor] are sweet, flat.[function cures mainly] invigorating the liver and kidney, moistening five ZANG-organs.Treating the liver kidney deficiency, wind syndrome caused by deficiency is dizzy, migratory arthralgia, paralysis, constipation due to dry stool, after being ill weakness with emaciation, early whitening of beard and hair, and married woman's breast is few." beautiful Chinese catalpa medicine solution ": " tonification seminal fluid, profit liver, tonifying the blood and stretching the tendon.Treat that language is not smoothgoing, step late, the dry dried and withered hairs of skin, marrow dry up that meat subtracts, breast less, through hindering all cards." " seal character of doctor's Fructus Kaki is wanted ": " black person energy YIN nourishing, mends stomach, sharp intestine and small intestine, slow liver, improving eyesight, removing heat from blood, relieving heat toxin.Russet person lays one's heart bear kidney.”
Alectoria asiatica Du Rietz, [nature and flavor] are light, flat.[function cures mainly] enriching yin and nourishing kidney, inducing diuresis to remove edema, improving eyesight.Control kidney deficiency and bodily weakness, headache, dizzy, cardiopalmus, seminal emission, night sweat, stranguria, edema, impetigo, order disease.
Tylorrhynchus heterochaeta Quatrefages, [nature and flavor] are sweet, temperature.[function cures mainly] tonifying the spleen and stomach; Replenishing QI and blood; Inducing diuresis to remove edema.Main weakness of the spleen and stomach; Have loose bowels; Anemia; Edema." detailed outline is picked up any lost article from the road ": " tonifying the spleen and stomach, hemopoietic, dampness removing, row urine.”
Semen Alpiniae Katsumadai, [nature and flavor] are pungent, temperature.[function cures mainly] is drying damp and strengthening spleen, stomach warming preventing or arresting vomiting, warming middle-JIAO dampness; Circulation of qi promoting spleen invigorating.For internal retention of cold wetness, distension and fullness in the abdomen cold type of pain, belch vomiting, anorexia.
Radix Akebiae, [nature and flavor] are bitter; Property is put down.[function cures mainly] dispelling wind and removing obstruction in the collateral; Inducing diuresis to remove edema; Circulation of qi promoting; Invigorate blood circulation; Invigorating the liver and kidney; Bone and muscle strengthening.Main air pain of dampness syndrome; Traumatic injury; Amenorrhea; Hernia; Painful and swollen testis; Gastral cavity abdominal distention is vexed; Dysuria; Leukorrhagia; Worm venom.
Li Jisheng, [nature and flavor] are bitter; Sweet; Tepor.[function cures mainly] wind-damp dispelling; Invigorating the liver and kidney; Promoting flow of QI and blood; Pain relieving.Main air pain of dampness syndrome; Numb limbs and tense tendons; Soreness of waist and knee joint; Have a dizzy spell; Traumatic injury.
Flos Caraganae intermediae, [nature and flavor] are sweet, temperature.[function cures mainly] nourishing YIN and benefiting blood.Control hypertension, dizziness.
White Radix et Rhizoma Dysosmatis, [nature and flavor] sweet in the mouth; Bitter; Property is put down.[function cures mainly] enriching yin and nourishing kidney; Clearing away lung-heat and moistening for dryness; Removing toxic substances and promoting subsidence of swelling.Main impairment caused by overstrain bones and muscles pain; Sexual impotence; Stomachache; Innominate toxic swelling; Weapons wound.
Musk orchid, [nature and flavor] are sweet, temperature.[function cures mainly] enriching yin and nourishing kidney, nourishing the stomach, regulating menstruation.For neurasthenia, dizzy insomnia, irritated thirsty inappetence, early whitening of beard and hair, menoxenia.
Rhizoma Polygonati Cirrhifolii, [nature and flavor] put down, sweet." Shaanxi Chinese herbal medicine ": " spleen reinforcing lung moistening, enriching yin and nourishing kidney, promoting flow of QI and blood, astringing to arrest bleeding, sterilization of drawing out pus by applying a plaster to the affected part.Control insufficiency of the spleen few food, cough due to deficiency of the lung, dizzy bodily pain, seminal emission night sweat, metrorrhagia leucorrhea, furuncle is from the beginning of, scrofula.”
Suona horn flower, nature and flavor] bitter in the mouth; Micro-pungent; Property is put down.[function cures mainly] invigorating spleen to remove dampness; Promoting flow of QI and blood.Master has loose bowels; Dysentery; Stomachache; Hypochondriac pain; Rheumatalgia; Menoxenia; Carbuncle; Fracture.
Herba Stylophori Lasiocapi, [nature and flavor] bitter and puckery flavor, property is put down.[function cures mainly] promoting blood flow to regulate menstruation, circulation of qi promoting dissipating blood stasis, hemostasis and pain-relieving.Control traumatic injury, traumatic hemorrhage, impairment caused by overstrain, menoxenia, furuncle.
In order to express Chinese medicine of the present invention better, Chinese medicine of the present invention can be prepared into dosage form conventional clinically.Such as, the preparations such as powder, pill, sublimed preparation, granule, oral liquid, tablet, capsule, described pharmaceutical preparation all can prepare according to Chinese medicine preparation preparation method well-known to those skilled in the art.Preferably, Chinese medicine composition of the present invention conveniently preparation technology be prepared into powder, tablet or capsule.
Present invention also offers a kind of preparation method of above-mentioned Chinese medicine, it mainly comprises following step: get the above-mentioned Chinese crude drug of recipe quantity and be broken into coarse powder, the alcoholic solution that volumetric concentration is 45%-85% is doubly added according to the 5-10 of coarse powder gross weight, reflux, extract, three times, return time is 2-5h, filters, filtrate recycling ethanol, cold filtration, washes with water, namely obtains Chinese medical concrete after drying; Those skilled in the art can technically prepare conventional Chinese medicine pharmaceutical dosage form clinically, as tablet, capsule etc. in this preparation method.
Another object of the present invention is to provide a kind of medical usage, i.e. the purposes of above-mentioned Chinese medicine in preparation treatment hypertension drug.
The traditional Chinese medical science thinks that hypertension is liver,spleen,kidney imbalance, causes caused by Liver and kidney imbalance of YIN and YANG, nutrient blood loss, hematogenous blockage.So for controlling hypertension, its cause of disease of first dispelling.The present invention is with YIN nourishing invigorating the liver and kidney, and spleen reinforcing stomach invigorating, the spleen strengthening and damp drying, regulating qi to disperse stagnation is the rule for the treatment of.Fructus Ilicis Cornutae in prescription, Semen sesami Niger, Alectoria asiatica Du Rietz, white Radix et Rhizoma Dysosmatis, musk orchid have effect of YIN nourishing invigorating the liver and kidney, Fructus Mori, Flos Caraganae intermediae replenishing YIN and blood, spermatogenesis are moisturized, Radix Akebiae, Li Jisheng, Herba Stylophori Lasiocapi's promoting flow of QI and blood, Rhizoma Polygonati Cirrhifolii, Tylorrhynchus heterochaeta Quatrefages tonifying the spleen and stomach, Semen Alpiniae Katsumadai, suona horn are spent drying damp and strengthening spleen.With above-mentioned ten pleasant impression Chinese herbal medicine through dialectical prescription, organic compatibility, mutually assist a ruler in governing a country, YIN nourishing tonifying liver can be reached, the strengthening the spleen and stomach that nourishes blood, blood-activating and qi-promoting, the effect of moisturizing of promoting the production of body fluid, thus realize the thoroughly hypertensive object for the treatment of.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention will be further described, but embodiment does not limit the present invention.
The preparation of embodiment 1 pharmaceutical preparation of the present invention
Prescription: Fructus Ilicis Cornutae 32 parts, Semen sesami Niger 30 parts, Li Jisheng 28 parts, Flos Caraganae intermediae 31 parts, Rhizoma Polygonati Cirrhifolii 38 parts, Herba Stylophori Lasiocapi 29 parts, 27 parts, Fructus Mori, Alectoria asiatica Du Rietz 10 parts, Tylorrhynchus heterochaeta Quatrefages 8 parts, Semen Alpiniae Katsumadai 11 parts, Radix Akebiae 10 parts, white Radix et Rhizoma Dysosmatis 7 parts, musk orchid 9 parts, suona horn spend 5 parts.
Preparation method: get the above-mentioned Chinese crude drug of recipe quantity and be broken into coarse powder, add according to 8 times of coarse powder gross weight the alcoholic solution that volumetric concentration is 75%, reflux, extract, three times, return time is 3h, filters, filtrate recycling ethanol, cold filtration, washes with water, namely obtains Chinese medical concrete after drying; Pulverize, filled capsules, 0.5g/ grain.
The preparation of embodiment 2 pharmaceutical preparation of the present invention
Prescription: Fructus Ilicis Cornutae 34 parts, Semen sesami Niger 32 parts, Li Jisheng 30 parts, Flos Caraganae intermediae 33 parts, Rhizoma Polygonati Cirrhifolii 40 parts, Herba Stylophori Lasiocapi 31 parts, 29 parts, Fructus Mori, Alectoria asiatica Du Rietz 12 parts, Tylorrhynchus heterochaeta Quatrefages 10 parts, Semen Alpiniae Katsumadai 13 parts, Radix Akebiae 12 parts, white Radix et Rhizoma Dysosmatis 9 parts, musk orchid 11 parts, suona horn spend 7 parts.
Preparation method is with embodiment 1.
The preparation of embodiment 3 pharmaceutical preparation of the present invention
Prescription: prescription: Fructus Ilicis Cornutae 33 parts, Semen sesami Niger 31 parts, Li Jisheng 29 parts, Flos Caraganae intermediae 32 parts, Rhizoma Polygonati Cirrhifolii 39 parts, Herba Stylophori Lasiocapi 30 parts, 28 parts, Fructus Mori, Alectoria asiatica Du Rietz 11 parts, Tylorrhynchus heterochaeta Quatrefages 9 parts, Semen Alpiniae Katsumadai 12 parts, Radix Akebiae 11 parts, white Radix et Rhizoma Dysosmatis 8 parts, musk orchid 10 parts, suona horn spend 6 parts.
Preparation method is with embodiment 1.
The clinical test of pesticide effectiveness of embodiment 4
(1) medical history information
Select case 300 example, age 31-72 year, course of disease 2-10, blood pressure 150-190mmHg/95-105mmHg.
(2) Therapeutic Method
Take capsule prepared by the embodiment of the present invention 3, every day 1 time, each 3 30 days is a course for the treatment of, treats two courses for the treatment of.
(3) efficacy assessment standard
Effective: diastolic pressure decline > 10 mmHg, and reach normal range; Diastolic pressure is not down to normally, but >=20 mmHg that decline.
Effective: diastolic pressure decline < 10 mmHg, does not reach normal range; Diastolic pressure decline 10-19 mmHg, but but do not reach normal range; Systolic pressure decline > 30 mmHg.
Invalid: not reach above standard.
(4) therapeutic outcome sees the following form
Known by the above results, Chinese medicine of the present invention has effect definite significantly for treatment hypertension, and total effective rate is 100%.
Claims (5)
1. treat a hypertensive Chinese medicine, it is characterized in that being obtained by the traditional Chinese medicinal material raw materials of following weight portion: Fructus Ilicis Cornutae 32-34 part, Semen sesami Niger 30-32 part, Li Jisheng 28-30 part, Flos Caraganae intermediae 31-33 part, Rhizoma Polygonati Cirrhifolii 38-40 part, Herba Stylophori Lasiocapi 29-31 part, Fructus Mori 27-29 part, Alectoria asiatica Du Rietz 10-12 part, Tylorrhynchus heterochaeta Quatrefages 8-10 part, Semen Alpiniae Katsumadai 11-13 part, Radix Akebiae 10-12 part, white Radix et Rhizoma Dysosmatis 7-9 part, musk orchid 9-11 part, suona horn flower 5-7 part.
2. the hypertensive Chinese medicine for the treatment of as claimed in claim 1, is characterized in that being obtained by the traditional Chinese medicinal material raw materials of following weight portion: Fructus Ilicis Cornutae 33 parts, Semen sesami Niger 31 parts, Li Jisheng 29 parts, Flos Caraganae intermediae 32 parts, Rhizoma Polygonati Cirrhifolii 39 parts, Herba Stylophori Lasiocapi 30 parts, 28 parts, Fructus Mori, Alectoria asiatica Du Rietz 11 parts, Tylorrhynchus heterochaeta Quatrefages 9 parts, Semen Alpiniae Katsumadai 12 parts, Radix Akebiae 11 parts, white Radix et Rhizoma Dysosmatis 8 parts, musk orchid 10 parts, suona horn spend 6 parts.
3. the hypertensive Chinese medicine for the treatment of as claimed in claim 1 or 2, is characterized in that: described Chinese medicine is powder, pill, sublimed preparation, granule, oral liquid, tablet or capsule.
4. prepare the method for the treatment of hypertensive Chinese medicine as claimed in claim 1 or 2 for one kind, it is characterized in that comprising following processing step: get recipe quantity Chinese crude drug and be broken into coarse powder, the alcoholic solution that volumetric concentration is 45%-85% is doubly added according to the 5-10 of coarse powder gross weight, reflux, extract, three times, return time is 2-5h, filters, filtrate recycling ethanol, cold filtration, washes with water, namely obtains Chinese medical concrete after drying; Those skilled in the art can technically prepare conventional Chinese medicine pharmaceutical dosage form clinically in this preparation method.
5. described in claim 1 or 2, treat the application of hypertensive Chinese medicine in preparation treatment hypertension drug.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105902781A (en) * | 2016-06-01 | 2016-08-31 | 邹城众达知识产权咨询服务有限公司 | Capsule preparation for control of high blood pressure |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103893728A (en) * | 2014-03-27 | 2014-07-02 | 张世敏 | Traditional Chinese medicine preparation for treating kidney deficiency hypertension |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103893728A (en) * | 2014-03-27 | 2014-07-02 | 张世敏 | Traditional Chinese medicine preparation for treating kidney deficiency hypertension |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105902781A (en) * | 2016-06-01 | 2016-08-31 | 邹城众达知识产权咨询服务有限公司 | Capsule preparation for control of high blood pressure |
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Application publication date: 20150429 |