CN104547207A - Externally applied traditional Chinese medicinal preparation for eliminating old scar and preparation method thereof - Google Patents
Externally applied traditional Chinese medicinal preparation for eliminating old scar and preparation method thereof Download PDFInfo
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Abstract
The invention discloses an externally applied traditional Chinese medicinal preparation for eliminating an old scar. The externally applied traditional Chinese medicinal preparation for eliminating the old scar is mainly prepared from the following raw materials in parts by weight: 10-15 parts of platycodon grandiflorum, 9-15 parts of carrot seeds, 6-10 parts of semen litchi, 5-10 parts of lithargite, 10-15 parts of folium artemisiae argyi, 9-16 parts of radix sophorae flavescentis, 8-16 parts of circium japonicum, 9-15 parts of frankincense, 6-12 parts of kansui root, 5-10 parts of pepper, 0.8-1.5 parts of cinnabar, 9-15 parts of fructus polygoni orientalis, 0.6-1.4 parts of peppermint essential oil and 0.8-1.3 parts of black spruce essential oil. The externally applied traditional Chinese medicinal preparation provided by the invention has use safety and no side effect and can be used for effectively eliminating the scar, and skin can return to normal.
Description
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to the Traditional Chinese medicine external preparation and preparation method of eliminating old cicatrix.
Background technology
Cicatrix is the mode of appearance of normal skin tissue caused after various wound and the general designation of tissue pathologies change, and it is product inevitable in human body processes of wound repair.Cicatrix growth exceedes certain limit, various complication will occur, the destruction of such as profile and functional activity obstacle etc., the cicatrix brought the painful and psychic pain of the huge human body to patient, especially burn, scald, leave over after severe trauma.The main method of existing medical means elimination cicatrix is chemotherapy, X-ray therapy, laser therapy, skin mill disappears art or excision transplantation etc., but these method curative effects are poor, easy recurrence, some also can obvious injured patient healthy, affects the normal studying and living of patient.
Publication No. CN 103251707 A(application number 201310189334.3) Chinese patent literature disclose a kind of for Chinese medicine composition eliminating cicatrix and preparation method thereof, be made by the raw material of following portions by weight: the Radix Angelicae Dahuricae 6 ~ 12 parts, Radix Salviae Miltiorrhizae 6 ~ 12 parts, Scolopendra 4 ~ 8 parts, Herba Taraxaci 5 ~ 10 parts, 3 ~ 8 parts, Flos Carthami, Radix Sanguisorbae 5 ~ 10 parts, Margarita powder 5 ~ 10 parts, Camphora 1 ~ 4 part, Mel 4 ~ 10 parts, 8 ~ 15 parts, vaseline.Publication No. CN 102579709 A(application number 201210086284.1) Chinese patent literature disclose a kind of for prevent cicatrix, eliminate cicatrix, treatment burn Chinese herbal and crude drugs preparations burn oil, be made up of Oleum sesami and following medicinal herb components: Herba Mimosae Pudicae, Flos Hibisci Mutabilis, Folium Hibisci Mutabilis, Flos Mume, Pyrus bretschneideri flower, Radix Et Rhizoma Rhei, Radix Zanthoxyli, Rhizoma Polygoni Cuspidati, Radix Scutellariae, Cortex Phellodendri, Fructus Gardeniae, Radix Angelicae Sinensis, Stigma Croci, the Radix Angelicae Dahuricae, Omphalia, Flos Caryophylli, Spina Gleditsiae.Publication No. CN 102755503 A(application number 201210284046.1) Chinese patent literature disclose a kind of Chinese medicine composition for the treatment of skin trauma, relate to technical field of Chinese medicine.In order to shorten the wound healing time of skin trauma, reduce or eliminate cicatrix, the present invention treats the Chinese medicine composition of skin trauma, obtained by the raw material of following weight portion: Flos Lonicerae 10-50 part, Sanguis Draxonis 10-20 part, Bulbus Allii 5-20 part, Cortex Phellodendri 5-15 part, Rhizoma Chuanxiong 5-15 part, Radix Platycodonis 1-10 part, Radix Angelicae Dahuricae 5-15 part, Herba Schizonepetae 9-15 part, Radix Lamiophlomidis Rotatae 0-10 part, Ovum crusta Gallus domesticus 0-20 part, egg yolk 0-5 part.
Be compared to the deficiency of doctor trained in Western medicine, the traditional Chinese medical science has more advantage in elimination old cicatrix, reasonably combined by multiple medical material, directly be applied in injury, reach effect of blood circulation promoting and blood stasis dispelling, detumescence and promoting granulation, but most of medicine, for old cicatrix DeGrain, therefore strengthens the research to the party's surface compositions, it is necessary for improving curative effect of medication further.
Summary of the invention
For the problem of prior art, the object of this invention is to provide the Traditional Chinese medicine external preparation of the wide elimination old cicatrix of a kind of Be very effective, the use safety suitability.
Technical scheme of the present invention is:
Eliminate the Traditional Chinese medicine external preparation of old cicatrix, be prepared from primarily of following bulk drugs, be weight portion: Radix Platycodonis 10-15; Fructus Dauci Sativae 9-15; Semen Litchi 6-10; Lithargyrum 5-10; Folium Artemisiae Argyi 10-15; Radix Sophorae Flavescentis 9-16; Radix Cirsii Japonici 8-16; Olibanum 9-15; Radix Kansui 6-12; Fructus Piperis 5-10; Cinnabaris 0.8-1.5; Fructus Polygoni Orientalis 9-15; Mentha arvensis L. syn.M.haplocalyxBrig quintessence oil 0.6-1.4; Picea mariana quintessence oil 0.8-1.3.
Preferably, Radix Platycodonis 11-14; Fructus Dauci Sativae 11-13; Semen Litchi 7-9; Lithargyrum 6-9; Folium Artemisiae Argyi 11-14; Radix Sophorae Flavescentis 10-15; Radix Cirsii Japonici 10-14; Olibanum 11-13; Radix Kansui 8-10; Fructus Piperis 6-9; Cinnabaris 1.0-1.3; Fructus Polygoni Orientalis 11-13; Mentha arvensis L. syn.M.haplocalyxBrig quintessence oil 0.8-1.2; Picea mariana quintessence oil 0.9-1.2.
More preferably, Radix Platycodonis 12.5; Fructus Dauci Sativae 12; Semen Litchi 8; Lithargyrum 7.5; Folium Artemisiae Argyi 12.5; Radix Sophorae Flavescentis 12.5; Radix Cirsii Japonici 12; Olibanum 12; Radix Kansui 9; Fructus Piperis 7.5; Cinnabaris 1.15; Fructus Polygoni Orientalis 12; Mentha arvensis L. syn.M.haplocalyxBrig quintessence oil 1.0; Picea mariana quintessence oil 1.05.
The preparation method of the Traditional Chinese medicine external preparation of described elimination old cicatrix, its step is as follows:
(1) get Semen Litchi to smash to pieces, with wet cloth parcel, be placed in saline and soak, after taking-up, be placed in pot, slow fire is slowly dried and is constantly stirred, and takes out after its surface turns yellow;
(2) get Adeps caprae seu ovis and be placed in heat fused in pot, add Fructus Dauci Sativae and Fructus Polygoni Orientalis, slow fire heats, and constantly stir-fries, and then takes out and is rolled into frost;
(3) get Lithargyrum and Cinnabaris, soak with liquorice beverage, draw iron filings with Magnet after taking-up, be then placed in non iron container, water flies into fine powder, dries, sieve at 60 DEG C;
(4) Radix Platycodonis, Radix Sophorae Flavescentis, Olibanum, Radix Kansui and Fructus Piperis are cleaned, add water and do not have medical material 5cm to soak, big fire is boiled to boiling, continues 15 minutes, then adds Folium Artemisiae Argyi, Radix Cirsii Japonici and step (1) (2) made medical material, turns little fire and decocts, collect filtrate after closing fire;
(5) add water step (4) remaining medicinal residues continuation decoction 20 minutes, mixing twice gained filtrate after filtering, add step (3) gained medicated powder while hot, stir, be evaporated to 1/2 of original volume, treat that it is cooled to room temperature, then add Mentha arvensis L. syn.M.haplocalyxBrig quintessence oil and Picea mariana quintessence oil, encapsulate to obtain externally applied formulation.
The preparation method of the Traditional Chinese medicine external preparation of described elimination old cicatrix, step (1) mesohalobic concentration is that 40%-60%(is preferred: brine strength is 45%-55%; Be more preferably: brine strength is 50%).
The preparation method of the Traditional Chinese medicine external preparation of described elimination old cicatrix, soaks 60-90 minute (preferably: soak 70-80 minute in step (1); Be more preferably: soak 75 minutes).
The preparation method of the Traditional Chinese medicine external preparation of described elimination old cicatrix, constantly stir-fries 10-20 minute (preferably: constantly stir-fry 12-18 minute in step (2); Be more preferably: constantly stir-fry 15 minutes).
The preparation method of the Traditional Chinese medicine external preparation of described elimination old cicatrix, crosses 180-220 mesh sieve (preferred: to cross 190-210 mesh sieve in step (3); Be more preferably: cross 200 mesh sieves).
The preparation method of the Traditional Chinese medicine external preparation of described elimination old cicatrix, the little fire of step (4) decocts 25-45 minute (preferably: little fire decocts 30-40 minute; Be more preferably: little fire decocts 35 minutes).
The preparation method of the Traditional Chinese medicine external preparation of described elimination old cicatrix, it is (preferred: medicinal residues add medical material gross weight 5-6 water doubly that step (5) Chinese medicine slag adds medical material gross weight 4-7 water doubly; Be more preferably: medicinal residues add the water of medical material gross weight 5.5 times).
The Traditional Chinese medicine external preparation scientific formulation of elimination old cicatrix provided by the invention, preparation method is simple.In addition, its excellent part also shows:
1, the present invention is made according to the proportioning raw materials principle of the traditional Chinese medical science, has effect of hard masses softening and resolving, detumescence and promoting granulation;
2, the present invention is directed to old cicatrix, can effectively alleviate skin bulge and pigementation, Be very effective;
3, medical material used herein, is conveniently easy to get, and can not increase the financial burden of patient.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
embodiment 1eliminate the Traditional Chinese medicine external preparation of old cicatrix, be prepared from (every part of 5g) primarily of following bulk drugs: Radix Platycodonis 10 parts, Fructus Dauci Sativae 9 parts, Semen Litchi 6 parts, Lithargyrum 5 parts, Folium Artemisiae Argyi 10 parts, Radix Sophorae Flavescentis 9 parts, Radix Cirsii Japonici 8 parts, Olibanum 9 parts, Radix Kansui 6 parts, 5 parts, Fructus Piperis, 0.8 part, Cinnabaris, Fructus Polygoni Orientalis 9 parts, Mentha arvensis L. syn.M.haplocalyxBrig quintessence oil is (purchased from Oshadhi Ao Shadi board, product specification 10ml, goods number 1031721350) 0.6 part, Picea mariana quintessence oil is (purchased from the fragrant orange red board of Absolute Aromas, product specification 10ml, article No. 1465) 0.8 part.The preparation method of the Traditional Chinese medicine external preparation of above-mentioned elimination old cicatrix is:
(1) get Semen Litchi to smash to pieces, with wet cloth parcel, be placed in concentration be 40% saline soak 60 minutes, after taking-up, be placed in pot, slow fire is slowly dried and is constantly stirred, and takes out after its surface turns yellow;
(2) get Adeps caprae seu ovis and be placed in heat fused in pot, add Fructus Dauci Sativae and Fructus Polygoni Orientalis, slow fire heats, and constantly stir-fries 10 minutes, then takes out and is rolled into frost;
(3) get Lithargyrum and Cinnabaris, soak with liquorice beverage, draw iron filings with Magnet after taking-up, be then placed in non iron container, water flies into fine powder, dries at 60 DEG C, crosses 180 mesh sieves;
(4) Radix Platycodonis, Radix Sophorae Flavescentis, Olibanum, Radix Kansui and Fructus Piperis are cleaned, add water and do not have medical material 5cm to soak, big fire is boiled to boiling, continues 15 minutes, then adds Folium Artemisiae Argyi, Radix Cirsii Japonici and step (1) (2) made medical material, turns little fire and decocts 25 minutes, collect filtrate after closing fire;
(5) water step (4) remaining medicinal residues being added medical material gross weight 4 times continues decoction 20 minutes, mixing twice gained filtrate after filtering, add step (3) gained medicated powder while hot, stir, be evaporated to 1/2 of original volume, treat that it is cooled to room temperature, then add Mentha arvensis L. syn.M.haplocalyxBrig quintessence oil and Picea mariana quintessence oil, encapsulate to obtain externally applied formulation.
embodiment 2eliminate the Traditional Chinese medicine external preparation of old cicatrix, be prepared from (every part of 5g) primarily of following bulk drugs: Radix Platycodonis 15 parts, Fructus Dauci Sativae 15 parts, Semen Litchi 10 parts, Lithargyrum 10 parts, Folium Artemisiae Argyi 15 parts, Radix Sophorae Flavescentis 16 parts, Radix Cirsii Japonici 16 parts, Olibanum 15 parts, Radix Kansui 12 parts, 10 parts, Fructus Piperis, 1.5 parts, Cinnabaris, Fructus Polygoni Orientalis 15 parts, Mentha arvensis L. syn.M.haplocalyxBrig quintessence oil is (purchased from Oshadhi Ao Shadi board, product specification 10ml, goods number 1031721350) 1.4 parts, Picea mariana quintessence oil is (purchased from the fragrant orange red board of Absolute Aromas, product specification 10ml, article No. 1465) 1.3 parts.The preparation method of the Traditional Chinese medicine external preparation of above-mentioned elimination old cicatrix is:
(1) get Semen Litchi to smash to pieces, with wet cloth parcel, be placed in concentration be 60% saline soak 90 minutes, after taking-up, be placed in pot, slow fire is slowly dried and is constantly stirred, and takes out after its surface turns yellow;
(2) get Adeps caprae seu ovis and be placed in heat fused in pot, add Fructus Dauci Sativae and Fructus Polygoni Orientalis, slow fire heats, and constantly stir-fries 20 minutes, then takes out and is rolled into frost;
(3) get Lithargyrum and Cinnabaris, soak with liquorice beverage, draw iron filings with Magnet after taking-up, be then placed in non iron container, water flies into fine powder, dries at 60 DEG C, crosses 220 mesh sieves;
(4) Radix Platycodonis, Radix Sophorae Flavescentis, Olibanum, Radix Kansui and Fructus Piperis are cleaned, add water and do not have medical material 5cm to soak, big fire is boiled to boiling, continues 15 minutes, then adds Folium Artemisiae Argyi, Radix Cirsii Japonici and step (1) (2) made medical material, turns little fire and decocts 45 minutes, collect filtrate after closing fire;
(5) water step (4) remaining medicinal residues being added medical material gross weight 7 times continues decoction 20 minutes, mixing twice gained filtrate after filtering, add step (3) gained medicated powder while hot, stir, be evaporated to 1/2 of original volume, treat that it is cooled to room temperature, then add Mentha arvensis L. syn.M.haplocalyxBrig quintessence oil and Picea mariana quintessence oil, encapsulate to obtain externally applied formulation.
Model case: xxx, male, 25 years old.Medical history: patient was once hurt by sharp weapon, cause abdominal part to stay cicatrix that one is about 4cm, shape is as caterpillar, attractive in appearance because affecting, and want for many years to eliminate this cicatrix, period uses various medicine, and effect is showed no effect always.
Listen friend recommendation Chinese traditional treatment effect pretty good, just have the idea of having a try in arms and use gained externally applied formulation of the present invention, uniform application, in affected part, is massaged one minute gently, (use before liking to sleep most) once a day, after patient uses two weeks, protruding cicatrix starts to diminish, and length reduces to some extent, adhere to employing two months, the colour of skin returns to normally substantially, and scar surface is smooth, is more or less the same with normal skin.
embodiment 3eliminate the Traditional Chinese medicine external preparation of old cicatrix, be prepared from (every part of 5g) primarily of following bulk drugs: Radix Platycodonis 11 parts, Fructus Dauci Sativae 11 parts, Semen Litchi 7 parts, Lithargyrum 6 parts, Folium Artemisiae Argyi 11 parts, Radix Sophorae Flavescentis 10 parts, Radix Cirsii Japonici 10 parts, Olibanum 11 parts, Radix Kansui 8 parts, 6 parts, Fructus Piperis, 1.0 parts, Cinnabaris, Fructus Polygoni Orientalis 11 parts, Mentha arvensis L. syn.M.haplocalyxBrig quintessence oil is (purchased from Oshadhi Ao Shadi board, product specification 10ml, goods number 1031721350) 0.8 part, Picea mariana quintessence oil is (purchased from the fragrant orange red board of Absolute Aromas, product specification 10ml, article No. 1465) 0.9 part.The preparation method of the Traditional Chinese medicine external preparation of above-mentioned elimination old cicatrix is:
(1) get Semen Litchi to smash to pieces, with wet cloth parcel, be placed in concentration be 45% saline soak 70 minutes, after taking-up, be placed in pot, slow fire is slowly dried and is constantly stirred, and takes out after its surface turns yellow;
(2) get Adeps caprae seu ovis and be placed in heat fused in pot, add Fructus Dauci Sativae and Fructus Polygoni Orientalis, slow fire heats, and constantly stir-fries 12 minutes, then takes out and is rolled into frost;
(3) get Lithargyrum and Cinnabaris, soak with liquorice beverage, draw iron filings with Magnet after taking-up, be then placed in non iron container, water flies into fine powder, dries at 60 DEG C, crosses 190 mesh sieves;
(4) Radix Platycodonis, Radix Sophorae Flavescentis, Olibanum, Radix Kansui and Fructus Piperis are cleaned, add water and do not have medical material 5cm to soak, big fire is boiled to boiling, continues 15 minutes, then adds Folium Artemisiae Argyi, Radix Cirsii Japonici and step (1) (2) made medical material, turns little fire and decocts 30 minutes, collect filtrate after closing fire;
(5) water step (4) remaining medicinal residues being added medical material gross weight 5 times continues decoction 20 minutes, mixing twice gained filtrate after filtering, add step (3) gained medicated powder while hot, stir, be evaporated to 1/2 of original volume, treat that it is cooled to room temperature, then add Mentha arvensis L. syn.M.haplocalyxBrig quintessence oil and Picea mariana quintessence oil, encapsulate to obtain externally applied formulation.
embodiment 4eliminate the Traditional Chinese medicine external preparation of old cicatrix, be prepared from (every part of 5g) primarily of following bulk drugs: Radix Platycodonis 14 parts, Fructus Dauci Sativae 13 parts, Semen Litchi 9 parts, Lithargyrum 9 parts, Folium Artemisiae Argyi 14 parts, Radix Sophorae Flavescentis 15 parts, Radix Cirsii Japonici 14 parts, Olibanum 13 parts, Radix Kansui 10 parts, 9 parts, Fructus Piperis, 1.3 parts, Cinnabaris, Fructus Polygoni Orientalis 13 parts, Mentha arvensis L. syn.M.haplocalyxBrig quintessence oil is (purchased from Oshadhi Ao Shadi board, product specification 10ml, goods number 1031721350) 1.2 parts, Picea mariana quintessence oil is (purchased from the fragrant orange red board of Absolute Aromas, product specification 10ml, article No. 1465) 1.2 parts.The preparation method of the Traditional Chinese medicine external preparation of above-mentioned elimination old cicatrix is:
(1) get Semen Litchi to smash to pieces, with wet cloth parcel, be placed in concentration be 55% saline soak 80 minutes, after taking-up, be placed in pot, slow fire is slowly dried and is constantly stirred, and takes out after its surface turns yellow;
(2) get Adeps caprae seu ovis and be placed in heat fused in pot, add Fructus Dauci Sativae and Fructus Polygoni Orientalis, slow fire heats, and constantly stir-fries 18 minutes, then takes out and is rolled into frost;
(3) get Lithargyrum and Cinnabaris, soak with liquorice beverage, draw iron filings with Magnet after taking-up, be then placed in non iron container, water flies into fine powder, dries at 60 DEG C, crosses 210 mesh sieves;
(4) Radix Platycodonis, Radix Sophorae Flavescentis, Olibanum, Radix Kansui and Fructus Piperis are cleaned, add water and do not have medical material 5cm to soak, big fire is boiled to boiling, continues 15 minutes, then adds Folium Artemisiae Argyi, Radix Cirsii Japonici and step (1) (2) made medical material, turns little fire and decocts 40 minutes, collect filtrate after closing fire;
(5) water step (4) remaining medicinal residues being added medical material gross weight 6 times continues decoction 20 minutes, mixing twice gained filtrate after filtering, add step (3) gained medicated powder while hot, stir, be evaporated to 1/2 of original volume, treat that it is cooled to room temperature, then add Mentha arvensis L. syn.M.haplocalyxBrig quintessence oil and Picea mariana quintessence oil, encapsulate to obtain externally applied formulation.
Model case: xxx, women, 34 years old.Medical history: during patient's life baby, owing to being cesarean, causing belly leaving one cicatrix, about have the projection of 5cm, is very ugly, has had a strong impact on the mood of patient, just wants to use Chinese medicine to eliminate cicatrix.
Friend is listened to introduce effect of the present invention pretty good, use this example gained externally applied formulation, uniform application, in affected part, is massaged one minute gently, (use before liking to sleep most) once a day, patient adheres to that use is after one month, and skin obviously improves, and cicatrix starts to fade away, continue again use after one month, projection returns to smooth, color compared with normal skin tone, almost indistinction.
embodiment 5eliminate the Traditional Chinese medicine external preparation of old cicatrix, be prepared from (every part of 5g) primarily of following bulk drugs: Radix Platycodonis 12.5 parts, Fructus Dauci Sativae 12 parts, Semen Litchi 8 parts, Lithargyrum 7.5 parts, Folium Artemisiae Argyi 12.5 parts, Radix Sophorae Flavescentis 12.5 parts, Radix Cirsii Japonici 12 parts, Olibanum 12 parts, Radix Kansui 9 parts, 7.5 parts, Fructus Piperis, 1.15 parts, Cinnabaris, Fructus Polygoni Orientalis 12 parts, Mentha arvensis L. syn.M.haplocalyxBrig quintessence oil is (purchased from Oshadhi Ao Shadi board, product specification 10ml, goods number 1031721350) 1.0 parts, Picea mariana quintessence oil is (purchased from the fragrant orange red board of Absolute Aromas, product specification 10ml, article No. 1465) 1.05 parts.The preparation method of the Traditional Chinese medicine external preparation of above-mentioned elimination old cicatrix is:
(1) get Semen Litchi to smash to pieces, with wet cloth parcel, be placed in concentration be 50% saline soak 75 minutes, after taking-up, be placed in pot, slow fire is slowly dried and is constantly stirred, and takes out after its surface turns yellow;
(2) get Adeps caprae seu ovis and be placed in heat fused in pot, add Fructus Dauci Sativae and Fructus Polygoni Orientalis, slow fire heats, and constantly stir-fries 15 minutes, then takes out and is rolled into frost;
(3) get Lithargyrum and Cinnabaris, soak with liquorice beverage, draw iron filings with Magnet after taking-up, be then placed in non iron container, water flies into fine powder, dries at 60 DEG C, crosses 200 mesh sieves;
(4) Radix Platycodonis, Radix Sophorae Flavescentis, Olibanum, Radix Kansui and Fructus Piperis are cleaned, add water and do not have medical material 5cm to soak, big fire is boiled to boiling, continues 15 minutes, then adds Folium Artemisiae Argyi, Radix Cirsii Japonici and step (1) (2) made medical material, turns little fire and decocts 35 minutes, collect filtrate after closing fire;
(5) water step (4) remaining medicinal residues being added medical material gross weight 5.5 times continues decoction 20 minutes, mixing twice gained filtrate after filtering, add step (3) gained medicated powder while hot, stir, be evaporated to 1/2 of original volume, treat that it is cooled to room temperature, then add Mentha arvensis L. syn.M.haplocalyxBrig quintessence oil and Picea mariana quintessence oil, encapsulate to obtain externally applied formulation.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Radix Platycodonis: nature and flavor: bitter, pungent is flat.Gui Jing: return lung meridian.Effect: lung qi dispersing, sore-throat relieving, eliminates the phlegm, evacuation of pus.Cure mainly: for cough with copious phlegm, uncomfortable in chest smooth, pharyngalgia, hoarseness, lung abscess vomiting pus, skin infection difficulty in discharging of pus.
Fructus Dauci Sativae: base is former: be the fruit of samphire Radix Dauci Sativae.Chemical analysis: seed reaches 1.6% containing volatile oil.Wherein containing australene, l-limonene, 1, 8-Cineole, Geraniol, acetic acid Mang cattle ester, cephrol, citral, caryophyllene, carotol, carotenol, cymol, asaricin, bisabolence etc.Still containing flavonoid fatty oil in seed.The glyceride of petroselinic acid, Palmic acid, oleic acid, linoleic acid etc., daucosterol etc. are had in fatty oil.Nature and flavor: bitter in the mouth; Pungent; Warm in nature.Gui Jing: return spleen; Kidney channel.Function cures mainly: dampness cold expelling; Diuretic parasite killing.Main chronic dysentery; Chronic diarrhea; Malnutrition due to parasitic infestation; Water kind; Cold womb is suffered from abdominal pain.
Semen Litchi: base is former: be the seed of sapindaceous plant Fructus Litchi.Chemical analysis: seed contains Saponin 1.12%, tannin 3.43%.Again containing α-(methylene cyclopropyl) glycine.Nature and flavor: sweet puckery, temperature.Gui Jing: enter liver, kidney channel.Function cures mainly: warming middle-JIAO, regulates the flow of vital energy, pain relieving.Control gastric abscess, colicky, women's pricking caused by the stagnation of QI and blood.
Lithargyrum: base is former: be sulfide-based galena race mineral galena refine silver, plumbous time deposition furnace bottom, or for being processed into product after plumbous melting.Composition: mainly containing lead oxide; Still containing field trashes such as a small amount of sandstone, metallic lead, Lead oxide brown, and micro lead, antimony, ferrum, calcium, magnesium etc.The property of medicine: salty, pungent, flat.Poisonous.Return liver, spleen channel.Function cures mainly: dampness, parasite killing, removing toxic substances, and convergence is anticorrosion.Treatment of ulcer festers and does not restrain for a long time, aphtha, eczema, scabies, bromhidrosis, tinea versicolor, wine Zha nose, burn and scald.Compatibility and incompatibility of drugs: this product is based on external, and long-term a large amount of use easily causes lead poisoning.For oral administration should be careful, can not be excessive, can not more than a week, the empty and anemia of pregnant woman of body, child prohibit clothes.
Folium Artemisiae Argyi: base is former: be the dried leaves of feverfew Chinese mugwort.Chemical analysis: containing volatile oil, is mainly I, 8-Folium eucalypti globueli (Eucalyptus globulus Labill.) essence, α-absinthol, α-phellandrene, β-Flos Caryophylli alkene, camphene, Camphora, carvone, trans reed alcohol, I-alpha-terpineol in oil.Nature and flavor: toil, temperature.Gui Jing: enter spleen, liver, kidney channel.Function cures mainly: blood of regulating the flow of vital energy, by cold-damp; Warming the meridian, hemostasis, antiabortive.Control trusted subordinate's cold type of pain, convulsion of having loose bowels, chronic dysentery, tells nosebleed, hematochezia, menoxenia, metrorrhagia, leukorrhagia, frequent fetal movement, carbuncle and ulcer, scabies.
Radix Sophorae Flavescentis: nature and flavor with return through: bitter, cold.GUIXIN, liver, stomach, large intestine, urinary bladder channel.There is heat clearing and damp drying, parasite killing, effect of diuresis.For hematodiarrhoea, have blood in stool, jaundice urine retention, leucorrhea with red and white discharge, swelling of the vulva pudendal pruritus, eczema, eczema, skin pruritus, scabies leprosy, external treatment trichomonal vaginitis.
Radix Cirsii Japonici: base is former: be the dry aerial parts of feverfew Ji.Summer, autumn two tap aerial parts when season, the flowers are in blossom, and removing impurity, dries.Nature and flavor with return through sweet, bitter, cold.GUIXIN, Liver Channel.Function with cure mainly: cooling blood for hemostasis, dissipating blood stasis removing toxicity for eliminating carbuncles.For epistaxis, spit blood, hematuria, has blood in stool, metrorrhagia, traumatic hemorrhage, carbuncle sore tumefacting virus.
Olibanum: nature and flavor with return through: pungent, bitter, temperature.GUIXIN, liver, spleen channel.To invigorate blood circulation effect of analgesic therapy, detumescence and promoting granulation.For obstruction of qi in the chest and cardialgia, gastralgia, dysmenorrhea amenorrhea, postpartum stagnation, addiction abdominal mass is suffered from abdominal pain, rheumatic arthralgia, the contracture of muscle arteries and veins, traumatic injury, carbuncle skin infection.
Radix Kansui: base is former: be the root of euphorbia plant Radix Kansui.Chemical analysis: root containing triterpenes, in have euphorbone, euphadienol, euphorbadienol, epi-euphol.Still containing Palmic acid, citric acid, oxalic acid, tannin, resin, glucose, sucrose, starch, vitamin B1 (7O microgram/gram).Nature and flavor: bitter sweet, cold, poisonous.Gui Jing: enter spleen, lung, kidney channel.Function cures mainly: removing water retention by purgation is drunk, and removing mass gathers.Logical two just.Swelling of harnessing the river is full, prolonged fluid-retention, blocked-up chest, and dysentery epilepsy is dysphagic, lump in the abdomen, constipation and anuresis.
Fructus Piperis (preferred black pepper): base is former: be the fruit of Piperaceae plant Fructus Piperis.When the fruit of fruit ear base portion starts to redden, cut fruit ear, after drying or drying, pitchy, take off fruit, common name " black pepper ".Nature and flavor: pungent, heat.Gui Jing: enter stomach, large intestine channel.Function cures mainly: warming middle-JIAO, the therapeutic method to keep the adverse QI flowing downwards, expectorant, removing toxic substances.Control cold-phlegm food stagnation, coldness and pain in the epigastrium, regurgitation, vomiting clear water, has loose bowels, cold-dysentery.And separate bromatotoxin.
Cinnabaris: base is former: be natural cinnabar Ore.Nature and flavor with return through: sweet, be slightly cold; Poisonous.GUIXIN warp.Have and clear away heart-fire relieving convulsion, calm the nerves, improving eyesight, effect of removing toxic substances.For palpitation and being susceptible to fright, insomnia and dreamful sleep, epilepsy is gone mad, infantile convulsion, blurring of vision, aphtha, sore throat, sore swollen toxin.
Fructus Polygoni Orientalis: base is former: be the fruit of polygonaceae plant Polygonum knotweed, pale persicaria or Folium Salicis Babylonicae knotweed.Nature and flavor: salty, cold.Function cures mainly: repercussive removing mass, invigorating spleen to remove dampness.Control flank disease amassing, dropsy, has a stomach-ache, lack of appetite abdominal distention, acute catarrhal conjunctivitis, and skin ulcer swells, scrofula.
Mentha arvensis L. syn.M.haplocalyxBrig quintessence oil: Mentha arvensis L. syn.M.haplocalyxBrig is the institute's year raw herbaceous plant hybridized by Mentha viridis L and water mint, separablely in leaf obtains Leptospermum scoparium quintessence oil.Main chemical compositions: menthol, menthone, glycoside and multiple free amino acid.Pharmacological properties: 1, to the effect of health: have good analgesic effect to headache, migraine, toothache; Carsick, seasick use Peppermint essential oil has the effect of relieving fainting, emesis; Be highly profitable to digestive system, particularly to stomach, liver and small intestinal, he has antitetanic function, can the smooth muscle of stomach, intestinal gently, therefore can treat intestinal colic, diarrhoea, dyspepsia, vomiting and regurgitation.2, to the effect of skin: improve eczema, tinea, scabies; Help to shrink blood capillary, refrigerant sensation is provided; Get rid of the choking phenomenon of toxicity alluvial; Remove blackhead, good to oiliness skin effect.
Picea mariana quintessence oil: base is former: distill from the aciculiform tender leaf of Lmabrian Black PiceameyeriRehd. Et Wils. tree and obtain.Picea mariana quintessence oil is a kind of senior massage quintessence oil, to mix be specially adapted to stimulate that to recover adrenal gland tired according to 5% concentration with hazelnut oil.Mix with Oleum menthae and Cedrus deoclar (Roxb.) G. Don oil and can produce splendid effect of refreshing oneself.The some other tradition application of Picea mariana quintessence oil also comprises whole body myalgia of releiving, and improves blood circulation and rheumatism.Hemlock oil can also promote asthma, the respiration capability of bronchitis and cough patient.
test example 1the present invention's (embodiment 5) gained eliminates the clinical practice of the Traditional Chinese medicine external preparation of old cicatrix:
Choose crowd: hospital dermatology department filter out old cicatrix patient 328 example, be burnings, scald, wound or Post operation wound healing formation scar tissue, be mainly distributed in face, cervical region, back and extremity.Wherein women 161 example, male 167 example, oldest is 65 years old, and minimal ages is 3 years old, and 34.8 years old mean age, the cicatrization time is all more than half a year.
Before test, patient is divided into two groups at random, experimental group 224 example and matched group 104 routine, two groups in sex, age, the course of disease, the state of an illness etc. without significant difference.Experimental group uses gained externally applied formulation of the present invention, and uniform application, in affected part, is massaged one minute gently, (uses before liking to sleep most) once a day; Matched group uses other conventional medicines (except scar cream, Kang Ruibao, scar one are pasted or Aloe glue etc.).Period in a medicine carries out Continuous Observation to two groups of patients, record symptom and change.
Curative effect determinate standard: reference literature criterion of therapeutical effect, effective: cicatrix place skin is moistened, without depression, projection, without cicatrix trace, after stopping treatment, Continuous Observation is unchanged after 1 month; Effective: cicatrix place skin is moistened, depression boss is not obvious, and cicatrix place skin colour is close to surrounding normal skin, and after stopping treatment, Continuous Observation is symptoms stabilize after 1 month; Invalid: cicatrix quality makes moderate progress, but after stopping treatment, symptom is restored.
Clinical effectiveness: after bimestrial treatment, the therapeutic outcome of two groups is as shown in table 1:
As seen from the above table, the total effective rate of experimental group is apparently higher than matched group, and treatments period, use products obtained therefrom of the present invention, the elimination cicatrix time used is shorter, and recovery situation comparatively other drug is good, illustrate that the present invention is evident in efficacy for elimination old cicatrix, effect obviously.
The Chinese medicine used in the present invention, wherein Radix Platycodonis can lung qi dispersing evacuation of pus, Fructus Dauci Sativae can dampness cold expelling, Semen Litchi can regulating QI to relieve pain, Lithargyrum can restrain anticorrosion, and Folium Artemisiae Argyi can be regulated the flow of vital energy hemostasis, and Radix Sophorae Flavescentis can heat clearing and damp drying, Radix Cirsii Japonici can dissipating blood stasis eliminating carbuncle, Olibanum can detumescence and promoting granulation, and Radix Kansui can removing water retention by purgation drink, removing mass gather, and Fructus Piperis can warming the middle warmer and descending qi, Cinnabaris can calm detoxify, Fructus Polygoni Orientalis can repercussive removing mass, adds Mentha arvensis L. syn.M.haplocalyxBrig quintessence oil and the specific balance of Picea mariana quintessence oil improves effect, can effectively eliminate old cicatrix, make skin recover normal, improve the self-confidence of patient.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.
Claims (10)
1. eliminate the Traditional Chinese medicine external preparation of old cicatrix, it is characterized in that, be prepared from primarily of following bulk drugs, be weight portion: Radix Platycodonis 10-15; Fructus Dauci Sativae 9-15; Semen Litchi 6-10; Lithargyrum 5-10; Folium Artemisiae Argyi 10-15; Radix Sophorae Flavescentis 9-16; Radix Cirsii Japonici 8-16; Olibanum 9-15; Radix Kansui 6-12; Fructus Piperis 5-10; Cinnabaris 0.8-1.5; Fructus Polygoni Orientalis 9-15; Mentha arvensis L. syn.M.haplocalyxBrig quintessence oil 0.6-1.4; Picea mariana quintessence oil 0.8-1.3.
2. the Traditional Chinese medicine external preparation eliminating old cicatrix as claimed in claim 1, is characterized in that, Radix Platycodonis 11-14; Fructus Dauci Sativae 11-13; Semen Litchi 7-9; Lithargyrum 6-9; Folium Artemisiae Argyi 11-14; Radix Sophorae Flavescentis 10-15; Radix Cirsii Japonici 10-14; Olibanum 11-13; Radix Kansui 8-10; Fructus Piperis 6-9; Cinnabaris 1.0-1.3; Fructus Polygoni Orientalis 11-13; Mentha arvensis L. syn.M.haplocalyxBrig quintessence oil 0.8-1.2; Picea mariana quintessence oil 0.9-1.2.
3. the Traditional Chinese medicine external preparation eliminating old cicatrix as claimed in claim 1, is characterized in that, Radix Platycodonis 12.5; Fructus Dauci Sativae 12; Semen Litchi 8; Lithargyrum 7.5; Folium Artemisiae Argyi 12.5; Radix Sophorae Flavescentis 12.5; Radix Cirsii Japonici 12; Olibanum 12; Radix Kansui 9; Fructus Piperis 7.5; Cinnabaris 1.15; Fructus Polygoni Orientalis 12; Mentha arvensis L. syn.M.haplocalyxBrig quintessence oil 1.0; Picea mariana quintessence oil 1.05.
4. the preparation method of the Traditional Chinese medicine external preparation of the elimination old cicatrix as described in as arbitrary in claim 1-3, it is characterized in that, step is as follows:
(1) get Semen Litchi to smash to pieces, with wet cloth parcel, be placed in saline and soak, after taking-up, be placed in pot, slow fire is slowly dried and is constantly stirred, and takes out after its surface turns yellow;
(2) get Adeps caprae seu ovis and be placed in heat fused in pot, add Fructus Dauci Sativae and Fructus Polygoni Orientalis, slow fire heats, and constantly stir-fries, and then takes out and is rolled into frost;
(3) get Lithargyrum and Cinnabaris, soak with liquorice beverage, draw iron filings with Magnet after taking-up, be then placed in non iron container, water flies into fine powder, dries, sieve at 60 DEG C;
(4) Radix Platycodonis, Radix Sophorae Flavescentis, Olibanum, Radix Kansui and Fructus Piperis are cleaned, add water and do not have medical material 5cm to soak, big fire is boiled to boiling, continues 15 minutes, then adds Folium Artemisiae Argyi, Radix Cirsii Japonici and step (1) (2) made medical material, turns little fire and decocts, collect filtrate after closing fire;
(5) add water step (4) remaining medicinal residues continuation decoction 20 minutes, mixing twice gained filtrate after filtering, add step (3) gained medicated powder while hot, stir, be evaporated to 1/2 of original volume, treat that it is cooled to room temperature, then add Mentha arvensis L. syn.M.haplocalyxBrig quintessence oil and Picea mariana quintessence oil, encapsulate to obtain externally applied formulation.
5. the preparation method eliminating the Traditional Chinese medicine external preparation of old cicatrix as claimed in claim 4, it is characterized in that, step (1) mesohalobic concentration is that 40%-60%(is preferred: brine strength is 45%-55%; Be more preferably: brine strength is 50%).
6. the preparation method eliminating the Traditional Chinese medicine external preparation of old cicatrix as claimed in claim 4, is characterized in that, soaks 60-90 minute (preferably: soak 70-80 minute in step (1); Be more preferably: soak 75 minutes).
7. the preparation method eliminating the Traditional Chinese medicine external preparation of old cicatrix as claimed in claim 4, is characterized in that, constantly stir-fries 10-20 minute (preferably: constantly stir-fry 12-18 minute in step (2); Be more preferably: constantly stir-fry 15 minutes).
8. the preparation method eliminating the Traditional Chinese medicine external preparation of old cicatrix as claimed in claim 4, is characterized in that, crosses 180-220 mesh sieve (preferred: to cross 190-210 mesh sieve in step (3); Be more preferably: cross 200 mesh sieves).
9. the preparation method eliminating the Traditional Chinese medicine external preparation of old cicatrix as claimed in claim 4, is characterized in that, the little fire of step (4) decocts 25-45 minute (preferably: little fire decocts 30-40 minute; Be more preferably: little fire decocts 35 minutes).
10. the preparation method eliminating the Traditional Chinese medicine external preparation of old cicatrix as claimed in claim 4, is characterized in that, it is (preferred: medicinal residues add medical material gross weight 5-6 water doubly that step (5) Chinese medicine slag adds medical material gross weight 4-7 water doubly; Be more preferably: medicinal residues add the water of medical material gross weight 5.5 times).
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