CN104524177A - Novel traditional Chinese medicine mixture for treating sphagitis - Google Patents

Novel traditional Chinese medicine mixture for treating sphagitis Download PDF

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Publication number
CN104524177A
CN104524177A CN201510049443.4A CN201510049443A CN104524177A CN 104524177 A CN104524177 A CN 104524177A CN 201510049443 A CN201510049443 A CN 201510049443A CN 104524177 A CN104524177 A CN 104524177A
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parts
radix
radiotherapy
chinese medicine
traditional chinese
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CN201510049443.4A
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刘秀平
褚磊
孙敬
靖景艳
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Qingdao Tumour Hospital
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Qingdao Tumour Hospital
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/80—Scrophulariaceae (Figwort family)
    • A61K36/808—Scrophularia (figwort)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236—Ligusticum (licorice-root)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/34—Campanulaceae (Bellflower family)
    • A61K36/346—Platycodon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/35—Caprifoliaceae (Honeysuckle family)
    • A61K36/355—Lonicera (honeysuckle)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/42—Cucurbitaceae (Cucumber family)
    • A61K36/428—Trichosanthes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/536—Prunella or Brunella (selfheal)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/752—Citrus, e.g. lime, orange or lemon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/80—Scrophulariaceae (Figwort family)
    • A61K36/804—Rehmannia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8966—Fritillaria, e.g. checker lily or mission bells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8968—Ophiopogon (Lilyturf)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
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  • Animal Behavior & Ethology (AREA)
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  • Alternative & Traditional Medicine (AREA)
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Abstract

The invention relates to a novel traditional Chinese medicine mixture for treating sphagitis. The novel traditional Chinese medicine mixture is prepared from the following components in parts by mass: 15-30 parts of radix scrophulariae, 10-15 parts of burdocks, 10-15 parts of platycodon grandiflorum, 10-20 parts of radix ophiopogonis, 15-30 parts of radices trichosanthis, 10-15 parts of pericarpium citri reticulatae, 15-30 parts of selfheal, 7-10 parts of raw liquorice, 10-20 parts of ligusticum wallichii, 15-30 parts of honeysuckles, 15-30 parts of dried radix rehmanniae and 15-30 parts of fritillary bulbs. The novel traditional Chinese medicine mixture provided by the invention has the effects of clearing away heat and toxic materials and nourishing yin and generating body fluid, and not only can be used for alleviating congestion, edema, erosion and anabrosis of mucosa of cavum pharyngis and formation of albuginea induced by radiotherapy and alleviating the symptoms of pharyngoxerosis and pharyngalgia, but also improving the effective rate of radiotherapy at neck, and the curative effect of radiotherapy is improved by 5-18%.

Description

A kind of herb mixture of novel therapeutic pharyngolaryngitis
Technical field
The invention belongs to Chinese drug preparation technique field, be specifically related to a kind of herb mixture of novel therapeutic pharyngolaryngitis.
Background technology
Head, modal toxicity is because radiation damage causes the hyperemia of pharyngeal cavity mucosa, edema, erosion and ulcer in neck malignant tumor patient radiotherapy, tunica albuginea is formed, clinical main manifestations is the disease such as dry pharynx, pharyngalgia, therefore patient often affects feed, even be forced to interrupt radiotherapy, these not only bring great misery to patient, have also had a strong impact on the effect of radiotherapy.
Summary of the invention
The present invention overcomes the deficiencies in the prior art, proposes a kind of herb mixture of novel therapeutic pharyngolaryngitis, and described herb mixture can treat the side reaction of head-cervical radiotherapy effectively, especially for radioactive pharyngitis, has good therapeutic effect.
Technical scheme of the present invention is: a kind of herb mixture of novel therapeutic pharyngolaryngitis, and the formula of described herb mixture and mass parts are: Radix Scrophulariae 15-30, Fructus Arctii 10-15, Radix Platycodonis 10-15, Radix Ophiopogonis 10-20, Radix Trichosanthis 15-30, Pericarpium Citri Reticulatae 10-15, Spica Prunellae 15-30, Radix Glycyrrhizae 7-10, Rhizoma Chuanxiong 10-20, Flos Lonicerae 15-30, Radix Rehmanniae 15-30, Bulbus Fritillariae Thunbergii 15-30.
Preparation method is: said medicine is directly carried out decocting extraction, and adjust about PH7, through centrifugal 300 order filtering and impurity removings, embedding, is prepared.Instructions about how to take medicine: each 20ml, every day 3 times, oral, within 7 days, be 1 course for the treatment of.
The invention has the beneficial effects as follows:
The present invention has the effect of heat-clearing and toxic substances removing, YIN nourishing and the production of body fluid promoting, can not only alleviate radiotherapy and cause the hyperemia of pharyngeal cavity mucosa, edema, erosion and ulcer, tunica albuginea is formed, and alleviates the symptom of dry pharynx, pharyngalgia, and the effective percentage of head-cervical radiotherapy can be improved, improve radiotherapy effect 5-18%.
Detailed description of the invention
Embodiment 1: the radiotherapy of nasopharyngeal carcinoma
Get Radix Scrophulariae 15g Fructus Arctii 12g Radix Platycodonis 15g 15g Radix Ophiopogonis Radix Trichosanthis 20g Pericarpium Citri Reticulatae 10g Spica Prunellae 15 Radix Glycyrrhizae 10 Rhizoma Chuanxiong 20g Flos Lonicerae 15g Radix Rehmanniae 30g Bulbus Fritillariae Thunbergii 15g, after preparation.Preparation method is: said medicine is directly carried out decocting extraction, and adjust about PH7, through centrifugal 300 order filtering and impurity removings, embedding, is prepared.Instructions about how to take medicine: each 20ml, every day 3 times, oral, within 7 days, be 1 course for the treatment of, improve radiotherapy effect 10%.
Embodiment 2: the lymphadenomatous radiotherapy of Cervical Malignant
Data or component are below changed, for the lymphadenomatous radiotherapy of Cervical Malignant
Radix Scrophulariae 30g Fructus Arctii 12g Radix Platycodonis 12g 15g Radix Ophiopogonis Radix Trichosanthis 15g Pericarpium Citri Reticulatae 10g Spica Prunellae 30 Radix Glycyrrhizae 10 Rhizoma Chuanxiong 15g Flos Lonicerae 15g Radix Rehmanniae 15g Bulbus Fritillariae Thunbergii 30g
Preparation method is: said medicine is directly carried out decocting extraction, and adjust about PH7, through centrifugal 300 order filtering and impurity removings, embedding, is prepared.Instructions about how to take medicine: each 20ml, every day 3 times, oral, within 7 days, be 1 course for the treatment of, improve radiotherapy effect 6%.
Embodiment 3: thyroid carcinoma metastasic cervical lymph nodes postoperation radiotherapy
Data or component are changed, for thyroid carcinoma metastasic cervical lymph nodes postoperation radiotherapy below
Radix Scrophulariae 20g Fructus Arctii 12g Radix Platycodonis 12g 15g Radix Ophiopogonis Radix Trichosanthis 15g Pericarpium Citri Reticulatae 10g Spica Prunellae 20g Radix Glycyrrhizae 8g Rhizoma Chuanxiong 15g Flos Lonicerae 15g Radix Rehmanniae 15g Bulbus Fritillariae Thunbergii 20g
Preparation method is: said medicine is directly carried out decocting extraction, and adjust about PH7, through centrifugal 300 order filtering and impurity removings, embedding, is prepared.Instructions about how to take medicine: each 20ml, every day 3 times, oral, within 7 days, be 1 course for the treatment of, improve radiotherapy effect 16%.
Embodiment 4: breast carcinoma metastasic cervical lymph nodes radiotherapy
Data or component are changed, for the radiotherapy of breast carcinoma metastasic cervical lymph nodes below
Radix Scrophulariae 15g Fructus Arctii 12g Radix Platycodonis 12g 15g Radix Ophiopogonis Radix Trichosanthis 15g Pericarpium Citri Reticulatae 15g Spica Prunellae 15g Radix Glycyrrhizae 7 g Rhizoma Chuanxiong 15g Flos Lonicerae 20g Radix Rehmanniae 15g Bulbus Fritillariae Thunbergii 15g
Preparation method is: said medicine is directly carried out decocting extraction, and adjust about PH7, through centrifugal 300 order filtering and impurity removings, embedding, is prepared.Instructions about how to take medicine: each 20ml, every day 3 times, oral, within 7 days, be 1 course for the treatment of, improve radiotherapy effect 18%.
Embodiment 5: epimere esophageal carcinoma radiotherapy
Data or component are changed, for the radiotherapy of epimere esophageal carcinoma below
Radix Scrophulariae 15g Fructus Arctii 12g Radix Platycodonis 15g 15g Radix Ophiopogonis Radix Trichosanthis 30g Pericarpium Citri Reticulatae 12g Spica Prunellae 15g Radix Glycyrrhizae 10g Rhizoma Chuanxiong 15g Flos Lonicerae 20g Radix Rehmanniae 20g Bulbus Fritillariae Thunbergii 15g
Preparation method is: said medicine is directly carried out decocting extraction, and adjust about PH7, through centrifugal 300 order filtering and impurity removings, embedding, is prepared.Instructions about how to take medicine: each 20ml, every day 3 times, oral, within 7 days, be 1 course for the treatment of.These tumor radiotherapies all can cause radioactive pharyngitis, therefore need to give Chinese medicine therapeutic alliance attenuation synergistic, improve radiotherapy effect 13%.

Claims (1)

1. a herb mixture for novel therapeutic pharyngolaryngitis, is characterized in that: the formula of described herb mixture and mass parts are: Radix Scrophulariae 15-30, Fructus Arctii 10-15, Radix Platycodonis 10-15, Radix Ophiopogonis 10-20, Radix Trichosanthis 15-30, Pericarpium Citri Reticulatae 10-15, Spica Prunellae 15-30, Radix Glycyrrhizae 7-10, Rhizoma Chuanxiong 10-20, Flos Lonicerae 15-30, Radix Rehmanniae 15-30, Bulbus Fritillariae Thunbergii 15-30;
Said medicine is directly carried out decocting extraction, and adjust about PH7, through centrifugal 300 order filtering and impurity removings, embedding, is prepared.
CN201510049443.4A 2015-01-31 2015-01-31 Novel traditional Chinese medicine mixture for treating sphagitis Pending CN104524177A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105495207A (en) * 2015-12-10 2016-04-20 覃瑞权 Beverage capable of preventing and treating chronic pharyngitis and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101757414A (en) * 2008-11-07 2010-06-30 唐超 Chinese medicinal pill for clearing pharyngeal heat and detoxicating
CN102861226A (en) * 2012-09-29 2013-01-09 曲延丽 Traditional Chinese medicine for treating sphagitis
CN103041149A (en) * 2012-12-23 2013-04-17 徐化利 Traditional Chinese medicine formula for treating chronic pharyngolaryngitis

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101757414A (en) * 2008-11-07 2010-06-30 唐超 Chinese medicinal pill for clearing pharyngeal heat and detoxicating
CN102861226A (en) * 2012-09-29 2013-01-09 曲延丽 Traditional Chinese medicine for treating sphagitis
CN103041149A (en) * 2012-12-23 2013-04-17 徐化利 Traditional Chinese medicine formula for treating chronic pharyngolaryngitis

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
任应化: "慢性咽炎证型分布及临床辨治效果分析", 《中医学报》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105495207A (en) * 2015-12-10 2016-04-20 覃瑞权 Beverage capable of preventing and treating chronic pharyngitis and preparation method thereof

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Application publication date: 20150422