CN104521979A - Insecticide composition containing thiobenzamide and neonicotinoid insecticide - Google Patents

Abstract

The invention relates to the technical field of pesticides, and in particular relates to an insecticide composition containing thiobenzamide and a neonicotinoid insecticide. The insecticide composition is composed of thiobenzamide and the neonicotinoid insecticide, wherein thiobenzamide is 3-bromo-N-[4-chloro-2-methyl-6-(methylaminothioformyl) benzene]-1-(3-chloropyridine-2-yl)-1H-pyrazol-5-formamide; the neonicotinoid insecticide is any one of dinotefuran, clothianidin, thiamethoxam, imidacloprid, cycloxaprid, acetamiprid, nitenpyram, imidaclothiz or thiacloprid; and the mass ratio of thiobenzamide to the neonicotinoid insecticide ranges from (1:50) to (50:1). The insecticide composition and the insecticide thereof have the obvious synergistic effect when compared with a single dosage, and can be used for effectively preventing and treating various crop insects; and the use dosage of pesticides is reduced, and the drug use cost is saved.

Description

Containing the Pesticidal combination of thiobenzamide and nicotinic insecticide

Technical field

The present invention relates to technical field of pesticide, specifically relate to a kind of Pesticidal combination and the preparation thereof that contain thiobenzamide and nicotinic insecticide.

Background technology

Chinese invention patent CN103109816A discloses thiobenzamide compounds and application thereof, and the general structure 1 of thiobenzamide compounds is:

Have the thiobenzamide compounds of above-mentioned general formula 1, not only have high activity to lepidoptera pest, and also have beyond thought high activity to sucking pest (as rice fulgorid), this compounds has well double controlling and acts on and comprehensive function.The applicant is chlorine according to the preferred R1 of general formula 1, and R2 is methyl, and synthesize Compound I of the present invention (hereinafter referred to as thiobenzamide) with reference to the method in Chinese patent CN103109816A, structural formula is as follows:

Although Compound I (i.e. thiobenzamide) is also the same with thiobenzamide compounds have outstanding insecticidal effect.But its long-term single use, easily develops immunity to drugs, insecticidal activity declines.Find through lot of experiments, thiobenzamide and nicotinic insecticide are composite, not only play synergistic effect, and also delay the pesticide resistance of damage by disease and insect to thiobenzamide and nicotinic insecticide, raising control efficiency.

Up to now, there is not yet thiobenzamide and the bactericide compounded relevant report of nicotinoids.

Summary of the invention

The object of the present invention is to provide a kind of Pesticidal combination and insecticide thereof, this Pesticidal combination and insecticide thereof have obvious synergistic effect relative to single dose, can effectively prevent and treat various crop pests, reduce the using dosage of agricultural chemicals, save drug cost.

For realizing above-mentioned object, the technical solution used in the present invention is as follows:

Containing the Pesticidal combination of thiobenzamide and nicotinic insecticide; this Pesticidal combination is made up of thiobenzamide and nicotinic insecticide, and described thiobenzamide is the bromo-N-of 3-[4-chloro-2-methyl-6-(methylamino thioformyl) benzene]-1-(3-chloropyridine-2-base)-1H-pyrazoles-5-formamide.When in Pesticidal combination of the present invention, reactive compound exists with specified weight ratio, syneryistic effect highly significant.Preferably, the weight ratio of thiobenzamide and nicotinic insecticide is 1:50 ~ 50:1.

Preferably, the weight ratio of described thiobenzamide and nicotinic insecticide is 1:30 ~ 30:1.

In the present invention, the structural formula of described thiobenzamide is as follows:

The nicotinic insecticide mentioned in the present invention is all known and the pesticide species be disclosed.The preferred nicotinic insecticide of the present invention is any one in MTI-446, clothianidin, Diacloden, Imidacloprid, cycloxaprid, Acetamiprid, Nitenpyram, imidaclothiz or thiacloprid, is more preferably any one in MTI-446, clothianidin, Diacloden, Imidacloprid.Wherein cycloxaprid CAS No.:116705 is the agricultural insecticide of the super-active of new generation of East China University of Science's research and development, toxicity of the special end.Chemical name: 9-((6-chloropyridine-3-base) methyl)-4-nitro-8-oxa--10,11-glyoxalidine also (2,3-a) dicyclo (3,2,1) pungent-3-alkene, English common name: cycloxaprid.

The present invention also provides a kind of agricultural insecticide, is made up of auxiliary material acceptable on above-mentioned Pesticidal combination and agricultural chemicals.Wherein auxiliary material is the mixture of a kind of and auxiliary agent in solid carrier or liquid-carrier.In order to ensure that insecticide has better insecticidal effect, as preferably, Pesticidal combination accounts for 0.1% ~ 80% of the gross weight of described agricultural insecticide, and further preferably, Pesticidal combination accounts for 1% ~ 60% of described insecticidal total weight.More preferably, Pesticidal combination accounts for 5% ~ 41% of described insecticidal total weight.

Carrier of the present invention can be solid or liquid, and any carrier being generally used for preparing insecticides all can use.Liquid-carrier comprises organic solvent and water, and organic solvent comprises one or more in 1-METHYLPYRROLIDONE, two wires oil, methyl oleate, C10 aromatic hydrocarbons, methyl naphthalene.Solid carrier comprise kaolin, diatomite, ammonium chloride, superphosphate, an ammonium, urea, borax, potassium chloride, urea, humic acid, white carbon, precipitated calcium carbonate, bentonite, talcous one or more.

Described auxiliary agent can comprise according to the requirement of different dosage form draws together surfactant, defoamer, thickener, disintegrant, binding agent and antifreezing agent, can also comprise other functional aids that the industry is conventional as required.

In the present invention, surfactant comprises emulsifier, wetting agent and dispersant, surfactant is alkylphenol polyoxyethylene, dispersing agent MF, aliphatic alcohol polyoxyvinethene phosphate, naphthalene sulfonic acid formaldehyde polymer sodium salt, sodium lignin sulfonate, alkylnaphthalene sulfonate, SOPA-270, lauryl sodium sulfate, polymeric polycarboxylic acid salt, polycarboxylate, phenethyl phenol polyethenoxy ether, calcium dodecyl benzene sulfonate, castor oil polyoxyethylene ether, fatty alcohol-polyoxyethylene ether, sodium metnylene bis-naphthalene sulfonate, fatty alcohol polyoxyethylene ether sulfate, methyl naphthalene sulfonate formaldehyde condensate, calcium lignosulfonate, TERWET-1007, alkyl benzene calcium sulfonate, Negel, methyl naphthalene sulfonic acid sodium, naphthalene sulfonic acid condensate sodium salt, fatty alcohol ethyl oxide, EO/PO block polyether, maleic acid-acrylic acid copolymer sodium salt, agriculture breast 601#, tallow ethyoxyl ammonium salt, phenolsulfonic acid condensation product sodium salt, lauryl alcohol polyethylene glycol oxide base ether, pull open one or more in powder.

Film forming agent comprises one or more in sodium carboxymethylcellulose, xanthans, polyvinyl alcohol, carboxymethyl cellulose, methylcellulose.Binding agent comprises one or more in starch, polyvinyl alcohol, methylcellulose, xanthans.Disintegrant comprises one or more in ammonium sulfate, sodium sulphate, sodium chloride.Thickener comprises one or more in polyvinyl alcohol, Magnesiumaluminumsilicate, xanthans.Antifreezing agent comprises one or more in glycerine, propane diols, urea.Defoamer is organosilicon.Preservative comprises one or more in starch Sodium Octenyl Succinate, Phenylsalicylate.Warning colouration comprises famille rose, acid red or magenta.

According to different user demands, insecticide provided by the invention is according to becoming various type according to the method preparation that this area is general.The formulation of insecticide of the present invention can be the one of seed treatment formulations, ultra low volume liquids, granule, missible oil, wetting powder, water dispersible granules or suspending agent.

Described seed treatment formulations comprises seed treatment solid pharmaceutical preparation and seed treatment liquid preparation.Seed treatment solid pharmaceutical preparation is seed treatment dry powder doses, seed treatment dispersibles pulvis, the solvable pulvis of seed treatment; Seed treatment liquid preparation is seed treatment liquor, seed treatment emulsion, seed treatment suspending agent, suspension seed-coating agent and seed treatment microcapsule suspending agent.As preferably, the embodiment of seed treatment formulations provided by the invention is seed treatment dry powder doses, suspension seed-coating agent, seed treatment microcapsule suspending agent.

The invention provides above-mentioned Pesticidal combination and the application of insecticide in control crop pests.Especially special efficacy is had to the rice fulgorid of crops, thrips, aphid.

Pesticidal combination of the present invention and insecticide can be used by commonsense method, as spraying cauline leaf process, also can soil treatment, and such as solid root spreads fertilizer over the fields or liquid fills with root, can also dress seed, to soak seed or seed pelleting uses.

The present invention has following beneficial effect relative to prior art:

1, Pesticidal combination of the present invention and insecticide thereof, has obvious synergistic effect compared with single dose, and the insecticidal effect of the Pesticidal combination after mixture significantly improves compared with its single dose, and its lasting period is long.

2, reduce using dosage, decrease cost accounting.

3, utilize two kinds of active components to carry out reasonably mixture to the different mode of action of insect, the different mechanism of action, both extended the Pesticide use life-span, delayed again the generation of pest resistance to insecticide.

Embodiment:

Below in conjunction with specific embodiment, the present invention is further described, but does not limit the invention to these embodiments.Following thiobenzamide all refers to the material of its chemistry bromo-N-of 3-[4-chloro-2-methyl-6-(methylamino thioformyl) benzene]-1-(3-chloropyridine-2-base)-1H-pyrazoles-5-formamide by name, thiobenzamide is synthesized by laboratory, and other medicaments are commercial; Unless otherwise indicated, all percentage is all weight percentage.

One, the preparation of seed treatment formulations

Embodiment 1 10% thiobenzamide MTI-446 suspension seed-coating agent (9:1)

Thiobenzamide 9%, MTI-446 1%, alkylphenol polyoxyethylene 2.5%, dispersing agent MF 2%, carboxymethyl cellulose 2%, xanthans 1.5%, glycerine 2%, famille rose 0.5%, water are mended to 100%.

Preparation technology: thiobenzamide and MTI-446, surfactant alkylphenol polyoxyethylene, dispersing agent MF are mixed by formula rate, then suitable quantity of water is added, use sand mill wet-milling, again material is transferred to and shears in still, add film forming agent carboxymethyl cellulose, xanthans, antifreezing agent glycerine, famille rose and remaining water, meet standard through high speed shear to viscosity, particle diameter, obtains the suspension seed-coating agent containing 10% thiobenzamide MTI-446.

According to the preparation technology that embodiment 1 is identical, preparation embodiment 2-embodiment 3.

Embodiment 2 10% thiobenzamide clothianidin suspension seed-coating agent (1:1)

Thiobenzamide 5%, clothianidin 5%, aliphatic alcohol polyoxyvinethene phosphate 2%, naphthalene sulfonic acid formaldehyde polymer sodium salt 2.5%, sodium lignin sulfonate 1%, polyvinyl alcohol 2%, propane diols 2%, acid red 0.5%, water are mended to 100%.

Embodiment 3 15% thiobenzamide Imidacloprid suspension seed-coating agent (14:1)

Thiobenzamide 14%, Imidacloprid 1%, alkylphenol polyoxyethylene 3%, alkylnaphthalene sulfonate 1.5%, polyvinyl alcohol 1%, carboxymethyl cellulose 1%, propane diols 2%, magenta 1%, water are mended to 100%.

Embodiment 4 11% thiobenzamide Diacloden seed treatment dry powder doses (1:10)

Thiobenzamide 1%, Diacloden 10%, SOPA-2702%, naphthalene sulfonic acid formaldehyde polymer sodium salt 2%, lauryl sodium sulfate 1.3%, sodium carboxymethylcellulose 2%, azogeramine .5%, kaolin are mended to 100%.

Preparation technology: by above-mentioned formula rate by thiobenzamide, Diacloden, surfactant aliphatic alcohol polyoxyvinethene phosphate, naphthalene sulfonic acid formaldehyde polymer sodium salt, lauryl sodium sulfate, binding agent sodium carboxymethylcellulose, acid red, kaolin carries out pulverizing and mixes and obtain 11% thiobenzamide Diacloden seed treatment dry powder doses.

According to the preparation technology that embodiment 4 is identical, preparation embodiment 5-embodiment 8.

Embodiment 5 15% thiobenzamide MTI-446 seed treatment dry powder doses (1:14)

Thiobenzamide 1%, MTI-446 14%, aliphatic alcohol polyoxyvinethene phosphate 1.5%, dispersing agent MF 2%, sodium lignin sulfonate 1.5%, polyvinyl alcohol 2%, magenta 0.5%, kaolin are mended to 100%.

Embodiment 6 12% thiobenzamide cycloxaprid seed treatment dry powder doses (1:1)

Thiobenzamide 6%, cycloxaprid 6%, polymeric polycarboxylic acid salt 3%, lauryl sodium sulfate 2.5%, polyvinyl alcohol 2%, famille rose 1.2%, kaolin are mended to 100%.

Embodiment 7 21% thiobenzamide Acetamiprid seed treatment dry powder doses (20:1)

Thiobenzamide 20%, Acetamiprid 1%, naphthalene sulfonic acid formaldehyde polymer sodium salt 2%, polymeric polycarboxylic acid salt 1.5%, sodium lignin sulfonate 1%, methylcellulose 2%, famille rose 1%, kaolin are mended to 100%.

Embodiment 8 8% thiobenzamide thiacloprid seed treatment dry powder doses (3:1)

Thiobenzamide 6%, thiacloprid 2%, naphthalene sulfonic acid formaldehyde polymer sodium salt 2%, polycarboxylate 1.2%, sodium lignin sulfonate 1.3%, methylcellulose 2%, magenta 1%, diatomite are mended to 100%.

Two, the preparation of ultra low volume liquids

Embodiment 9:6% thiobenzamide MTI-446 ultra low volume liquids (5:1)

Thiobenzamide 5%, MTI-446 1%, 1-METHYLPYRROLIDONE 12%, phenethyl phenol polyethenoxy ether 3%, calcium dodecyl benzene sulfonate 1.5%, two wires oil complement to 100%.

Preparation technology: by formula rate first with solvent by after thiobenzamide, MTI-446 stirring and dissolving, then add surfactant, be fully uniformly mixed, obtain 6% thiobenzamide MTI-446 ultra low volume liquids.

According to the preparation technology that embodiment 9 is identical, preparation embodiment 10-embodiment 11.

Embodiment 10:8% thiobenzamide clothianidin ultra low volume liquids (1:3)

Thiobenzamide 2%, clothianidin 6%, 1-METHYLPYRROLIDONE 15%, methyl oleate 5%, castor oil polyoxyethylene ether 2%, fatty alcohol-polyoxyethylene ether 1.5%, calcium dodecyl benzene sulfonate 1%, C10 aromatic hydrocarbons complement to 100%.

Embodiment 11:11% thiobenzamide Diacloden ultra low volume liquids (10:1)

Thiobenzamide 10%, Diacloden 1%, 1-METHYLPYRROLIDONE 20%, methyl naphthalene 6%, alkylphenol polyoxyethylene 3.5%, calcium dodecyl benzene sulfonate 2%, ethyl oleate complement to 100%.

Three, the preparation of granule

Embodiment 12:1% thiobenzamide MTI-446 granule (1:9)

Thiobenzamide 0.1%, MTI-446 0.9%, sodium lignin sulfonate 3%, fatty alcohol-polyoxyethylene ether 2%, polyvinyl alcohol 3%, ammonium chloride 3%, superphosphate 2%, an ammonium 1%, urea supplies 100%.

Preparation technology: mixed by above-mentioned recipe ingredient, pulverizes, adds granulation in roller pelletizer, is drying to obtain granule containing 1% thiobenzamide MTI-446.

According to the preparation technology that embodiment 12 is identical, preparation embodiment 10-embodiment 17.

Embodiment 13:5% thiobenzamide MTI-446 granule (1:4)

Thiobenzamide 1%, MTI-446 4%, naphthalene sulfonic acid formaldehyde polymer sodium salt 3%, sodium metnylene bis-naphthalene sulfonate 2%, fatty alcohol-polyoxyethylene ether 1%, methylcellulose 3%, ammonium chloride 3%, superphosphate 2%, humic acid 1%, urea supplies 100%.

Embodiment 14:6% thiobenzamide clothianidin granule (1:5)

Thiobenzamide 1%, clothianidin 5%, naphthalene sulfonic acid formaldehyde polymer sodium salt 2%, polymeric polycarboxylic acid salt 1.5%, methylcellulose 2%, urea 2%, borax are mended to 100%.

Embodiment 15:0.5% thiobenzamide Diacloden granule (1:4)

Thiobenzamide 0.1%, Diacloden 0.4%, sodium metnylene bis-naphthalene sulfonate 3%, lauryl sodium sulfate 1%, polyvinyl alcohol 1%, ammonium chloride 2%, potassium chloride 2%, urea are mended to 100%.

Embodiment 16 6% thiobenzamide Imidacloprid granule (1:2)

Thiobenzamide 2%, Imidacloprid 4%, sodium lignin sulfonate 2%, naphthalene sulfonic acid formaldehyde polymer sodium salt 3%, starch 2%, humic acid 5%, urea are mended to 100%.

Embodiment 17 9.3% thiobenzamide cycloxaprid granule (30:1)

Thiobenzamide 9%, cycloxaprid 0.3%, fatty alcohol polyoxyethylene ether sulfate 1%, naphthalene sulfonic acid formaldehyde polymer sodium salt 3.5%, starch 2%, kaolin are mended to 100%.

Four, the preparation of wetting powder

Embodiment 18:51% thiobenzamide clothianidin wetting powder (1:50)

Thiobenzamide 1%, clothianidin 50%, lauryl sodium sulfate 4%, sodium lignin sulfonate 3.6%, white carbon 10%, kaolin supply 100%.

Preparation technology: above-mentioned recipe ingredient is mixed, then through air-flow crushing to certain particle diameter, i.e. obtained 51% thiobenzamide clothianidin wetting powder.

According to the preparation technology that embodiment 18 is identical, preparation embodiment 18-embodiment 28.

Embodiment 19:21% thiobenzamide clothianidin wetting powder (20:1)

Thiobenzamide 20%, clothianidin 1%, methyl naphthalene sulfonate formaldehyde condensate 2.5%, polymeric polycarboxylic acid salt 2.4%, precipitated calcium carbonate 3%, bentonite supply 100%.

Embodiment 20 33% thiobenzamide clothianidin wetting powder (1:10)

Thiobenzamide 3%, clothianidin 30%, methyl naphthalene sulfonic acid sodium 3%, alkyl benzene calcium sulfonate 2.5%TERWET-10072%, kaolin complement to 100%.

Embodiment 21:31% thiobenzamide MTI-446 wetting powder (30:1)

Thiobenzamide 30%, MTI-446 1%, polymeric polycarboxylic acid salt 3%, Negel 4%, precipitated calcium carbonate 5%, kaolin supply 100%.

CK1:20% thiobenzamide wetting powder

Thiobenzamide 20%, polymeric polycarboxylic acid salt 3%, Negel 4%, precipitated calcium carbonate 5%, kaolin supply 100%.

Embodiment 22 20% thiobenzamide MTI-446 wetting powder (1:9)

Thiobenzamide 2%, MTI-446 18%, calcium lignosulfonate 5%, methyl naphthalene sulfonic acid sodium 3%, polycarboxylate 5%, precipitated calcium carbonate 10%, bentonite complement to 100%.

Embodiment 23 21% thiobenzamide cycloxaprid wettable powder (1:20)

Thiobenzamide 1%, cycloxaprid 20%, calcium lignosulfonate 5%, alkylphenol polyoxyethylene 3%, pull open powder 5%, white carbon 6%, kaolin complements to 100%.

CK2:20% cycloxaprid wettable powder

Cycloxaprid 20%, calcium lignosulfonate 5%, alkylphenol polyoxyethylene 3%, pull open powder 5%, white carbon 6%, kaolin complements to 100%.

Embodiment 24 60% thiobenzamide Diacloden wetting powder (4:1)

Thiobenzamide 48%, Diacloden 12%, naphthalene sulfonic acid condensate sodium salt 5%, polycarboxylate 3%, precipitated calcium carbonate 10%, diatomite complement to 100%.

Embodiment 25:55% thiobenzamide thiacloprid wetting powder (1:10)

Thiobenzamide 5%, thiacloprid 50%, naphthalene sulfonic acid condensate sodium salt 4.3%, calcium lignosulfonate 2%, polymeric polycarboxylic acid salt 1%, kaolin supply 100%.

Embodiment 26:30% thiobenzamide imidaclothiz wetting powder (1:14)

Thiobenzamide 2%, imidaclothiz 28%, naphthalene sulfonic acid condensate sodium salt 3.5%, polymeric polycarboxylic acid salt 2%, white carbon 2%, diatomite supply 100%.

Embodiment 27:18% thiobenzamide imidacloprid wettable powder (2:1)

Thiobenzamide 12%, Imidacloprid 6%, dispersing agent MF 3%, polymeric polycarboxylic acid salt 2%, white carbon 10%, kaolin supply 100%.

Embodiment 28:80% thiobenzamide Nitenpyram wetting powder (9:1)

Thiobenzamide 72%, Nitenpyram 8%, naphthalene sulfonic acid formaldehyde polymer sodium salt 3.5%, sodium lignin sulfonate 2%, white carbon 6%, kaolin supply 100%.

Five, the preparation of suspending agent

Embodiment 29:11% thiobenzamide MTI-446 suspending agent (1:10)

Thiobenzamide 1%, MTI-446 10%, fatty alcohol ethyl oxide 4%, EO/PO block polyether 1%, maleic acid-acrylic acid copolymer sodium salt 2%, polymeric polycarboxylic acid salt 3%, polyvinyl alcohol 0.5%, urea 2%, organosilicon 0.1%, water supply 100%.

Preparation technology: put into by above-mentioned formula in high shear homogeneous emulsifying machine, high speed shear 25 minutes, then sand milling 90 minutes in pump to sand mill, obtain 11% thiobenzamide MTI-446 suspending agent (1:10).

According to the preparation technology that embodiment 30 is identical, preparation embodiment 30-embodiment 37.

Embodiment 30:20.5% thiobenzamide MTI-446 suspending agent (40:1)

Thiobenzamide 20%, MTI-446 0.5%, agriculture breast 601#2%, polymeric polycarboxylic acid salt 4%, dodecyl sulphate calcium 1%, Magnesiumaluminumsilicate 0.4%, urea 2%, organosilicon 0.1%, water supply 100%.

Embodiment 31:22% thiobenzamide clothianidin suspending agent (10:1)

Thiobenzamide 20%, clothianidin 2%, fatty alcohol-polyoxyethylene ether 3%, sodium metnylene bis-naphthalene sulfonate 2.5%, EO/PO block co-polyether 2%, xanthans 0.3%, glycerine 2%, organosilicon 0.01%, water are mended to 100%.

Embodiment 32:15% thiobenzamide acetamiprid suspending agent (4:1)

Thiobenzamide 12%, Acetamiprid 3%, tallow ethyoxyl ammonium salt 2%, phenolsulfonic acid condensation product sodium salt 2%, methyl naphthalene sulfonate formaldehyde condensate 2.5%, starch Sodium Octenyl Succinate 2%, glycerine 2%, organosilicon 0.2%, water supply 100%.

Embodiment 33:10% thiobenzamide cycloxaprid suspending agent (4:1)

Thiobenzamide 8%, cycloxaprid 2%, alkylnaphthalene sulfonate 2%, fatty alcohol polyoxyethylene ether sulfate 1.3%, phenolsulfonic acid condensation product sodium salt 2%, glycerine 2%, organosilicon 0.1%, water supply 100%.

Embodiment 34:11% thiobenzamide imidacloprid suspending agent (10:1)

Thiobenzamide 10%, Imidacloprid 1%, fatty alcohol-polyoxyethylene ether 2.5%, alkylnaphthalene sulfonate 3%, sodium metnylene bis-naphthalene sulfonate 1%, maleic-acrylic acid homopolymers sodium salt 3%, xanthans 0.5%, glycerine 2%, organosilicon 0.1%, water supply 100%.

Embodiment 35:6.2% thiobenzamide imidacloprid suspending agent (30:1)

Thiobenzamide 6%, Imidacloprid 0.2%, fatty alcohol-polyoxyethylene ether 2%, alkylnaphthalene sulfonate 3.2%, maleic-acrylic acid homopolymers sodium salt 3%, Magnesiumaluminumsilicate 0.6%, propane diols 2%, organosilicon 0.1%, water supply 100%.

Embodiment 36:21% thiobenzamide imidacloprid suspending agent (1:20)

Thiobenzamide 1%, Imidacloprid 20%, lauryl alcohol polyethylene glycol oxide base ether 2.3%, alkylnaphthalene sulfonate 3%, sodium metnylene bis-naphthalene sulfonate 4%, xanthans 0.05%, Magnesiumaluminumsilicate 0.6%, glycerine 2%, organosilicon 0.1%, water supply 100%.

Embodiment 37:6.3% thiobenzamide thiacloprid suspending agent (20:1)

Thiobenzamide 6%, thiacloprid 0.3%, fatty alcohol-polyoxyethylene ether 2%, alkylnaphthalene sulfonate 3.2%, sodium metnylene bis-naphthalene sulfonate 1%, Magnesiumaluminumsilicate 0.6%, glycerine 2%, Phenylsalicylate 0.4%, organosilicon 0.1%, water supply 100%.

Six, the preparation of water dispersible granules

Embodiment 38:21% thiobenzamide MTI-446 water dispersible granules (20:1)

Thiobenzamide 20%, MTI-446 1%, lignosulfonates 3%, naphthalene sulfonate 3.0%, ammonium sulfate 15%, xanthans 1%, talcum powder 1%, kaolin are supplied 100% and are fully mixed, then by air-flow crushing, granulating and forming obtains water dispersible granules.Containing 21% content reactive compound in water dispersible granules, product cut size is 0.8-2mm.

Preparation technology: mix by above-mentioned formula rate and carry out ultra-fine grinding, then carry out compression granulation or rotary table granulation, carries out being drying to obtain 21% thiobenzamide MTI-446 water dispersible granules.

According to the preparation technology that embodiment 38 is identical, preparation embodiment 39-embodiment 51.

Embodiment 39:30% thiobenzamide MTI-446 water dispersible granules (1:1)

Thiobenzamide 15%, MTI-446 15%, EO/PO block polyether 4%, naphthalene sulfonate 3%, starch 5%, xanthans 1%, diatomite supply 100%.

Embodiment 40:1% thiobenzamide MTI-446 water dispersible granules (1:4)

Thiobenzamide 0.02%, MTI-446 0.08%, lignosulfonates 5.0%, sodium metnylene bis-naphthalene sulfonate 3%, sodium sulphate 10%, xanthans 1%, bentonite supply 100%.

Embodiment 41:21% thiobenzamide clothianidin water dispersible granules (1:20)

Thiobenzamide 1%, clothianidin 20%, fatty alcohol-polyoxyethylene ether 5%, lignosulfonates 3.5%, methylcellulose 3%, ammonium sulfate 2%, white carbon 5%, bentonite supply 100%.

Embodiment 42:62% thiobenzamide clothianidin water dispersible granules (1:30)

Thiobenzamide 2%, clothianidin 60%, lauryl sodium sulfate 5%, fatty alcohol-polyoxyethylene ether 5%, sodium sulphate 4%, xanthans 1%, kaolin supply 100%.

Embodiment 43:25% thiobenzamide Diacloden water dispersible granules (4:1)

Thiobenzamide 20%, Diacloden 5%, EO/PO block polyether 3.8%, fatty alcohol-polyoxyethylene ether 6%, sodium chloride 11%, xanthans 2%, white carbon 10%, diatomite supply 100%.

Embodiment 44:15% thiobenzamide Diacloden water dispersible granules (1:14)

Thiobenzamide 1%, Diacloden 14%, lauryl sodium sulfate 4.2%, fatty alcohol-polyoxyethylene ether 5.8%, methylcellulose 2%, kaolin supply 100%.

Embodiment 45:31% thiobenzamide Diacloden water dispersible granules (30:1)

Thiobenzamide 30%, Diacloden 1%, lignosulfonates 6%, naphthalene sulfonate 3%, polyvinyl alcohol 1%, precipitated calcium carbonate 5%, kaolin supply 100%.

Embodiment 46:41% thiobenzamide imidacloprid water dispersible granule (40:1)

Thiobenzamide 40%, Imidacloprid 1%, lignosulfonates 5.0%, naphthalene sulfonate 3%, sodium sulphate 10%, xanthans 1%, bentonite supply 100%.

Embodiment 47:32% thiobenzamide cycloxaprid water dispersible granule (1:15)

Thiobenzamide 2%, cycloxaprid 30%, naphthalene sulfonic acid formaldehyde polymer sodium salt 4%, lignosulfonates 1.8%, starch 3%, white carbon 5%, kaolin supply 100%.

Embodiment 48:51% thiobenzamide cycloxaprid water dispersible granule (1:50)

Thiobenzamide 1%, cycloxaprid 50%, naphthalene sulfonic acid formaldehyde polymer sodium salt 3%, lignosulfonates 2.5%, polyvinyl alcohol 3%, white carbon 5%, bentonite supply 100%.

Embodiment 49:51% thiobenzamide Nitenpyram water dispersible granules (1:50)

Thiobenzamide 1%, Nitenpyram 50%, EO/PO block polyether 4%, lignosulfonates 2.8%, starch 5%, polyvinyl alcohol 2%, precipitated calcium carbonate 3%, diatomite supply 100%.

Embodiment 50:25% thiobenzamide Nitenpyram water dispersible granules (24:1)

Thiobenzamide 24%, Nitenpyram 1%, fatty alcohol-polyoxyethylene ether 4.0%, lignosulfonates 3.0%, sodium sulphate 15.0%, methylcellulose 2.0%, white carbon 2%, kaolin supply 100%.

Embodiment 51:10.2% thiobenzamide Nitenpyram water dispersible granules (50:1)

Thiobenzamide 10%, Nitenpyram 0.2%, fatty alcohol-polyoxyethylene ether 4%, lignosulfonates 3%, sodium sulphate 15.0%, polyvinyl alcohol 2%, white carbon 10%, kaolin supply 100%.

Bioassay test:

For determining thiobenzamide and the composite synergistic effect of nicotinic insecticide, the applicant uses these two kinds of compositions to carry out Toxicity Determination.

Data processing method: control efficiency is converted into probability value (y), liquor strength (μ g/m l) converts logarithm value (x) to, calculate virulence equation and concentration LC50 in suppressing with method of least squares, calculate toxicity index and the co-toxicity coefficient (CTC) of medicament according to the abundant method of Sun Yun.

Actual measurement toxicity index (ATI)=(standard agent LC50/ reagent agent LC50) × 100

In theoretical toxicity index (TTI)=A medicament toxicity index × mixture A percentage composition+B medicament toxicity index × mixture in the percentage composition of B

Co-toxicity coefficient (CTC)=[the theoretical toxicity index (TTI) of mixture actual measurement toxicity index (ATI)/mixture] × 100

Evaluation criterion: when CTC≤80, then composition shows as antagonism, and as 80 < CTC < 120, then composition shows as summation action, and when CTC >=120, then composition shows as synergistic effect.

Biologicall test example 1 prevents and treats the Toxicity Determination test of rice fulgorid

Test method: with reference to " NY/T1154.11-2008 farm-chemical indoor determination test rule insecticide the 11st part: rice-stem dipping method ".

Table 1 thiobenzamide and dinotefuran mixed Toxicity Determination result of preventing and treating rice fulgorid

Process	LC50(μg/ml)	ATI	TTI	CTC
					Thiobenzamide (A)	38.25	100.00	/	/
MTI-446 (B)	8.61	444.25	/	/
					A:B＝50:1	28.50	134.21	106.75	125.72
A:B＝40:1	26.30	145.44	108.40	134.17
					A:B＝30:1	21.49	177.99	111.10	160.20

A:B＝20:1	19.41	197.06	116.39	169.31
					A:B＝14:1	15.28	250.33	122.95	203.60
A:B＝10:1	12.86	297.43	131.30	226.54
					A:B＝9:1	14.54	263.07	134.43	195.70
A:B＝5:1	12.92	296.05	157.38	188.12
					A:B＝4:1	12.78	299.30	168.85	177.26
A:B＝2:1	10.42	367.08	214.75	170.93
					A:B＝1:1	8.19	467.03	272.13	171.62
A:B＝1:2	7.06	541.78	329.50	164.43
					A:B＝1:4	6.32	605.22	375.40	161.22
A:B＝1:5	6.15	621.95	386.88	160.76
					A:B＝1:9	5.84	654.97	409.83	159.82
A:B＝1:10	6.02	635.38	412.96	153.86
					A:B＝1:14	5.97	640.70	421.30	152.08
A:B＝1:20	5.66	675.80	427.86	157.95
					A:B＝1:30	5.72	668.71	433.15	154.38
A:B＝1:34	5.90	648.31	434.42	149.24
					A:B＝1:40	6.32	605.22	435.85	138.86
A:B＝1:50	6.84	559.21	437.50	127.82

Table 2 thiobenzamide and clothianidin mixture prevent and treat the Toxicity Determination result of rice fulgorid

Process	LC50(μg/ml)	ATI	TTI	CTC
					Thiobenzamide (A)	38.17	100.00	/	/
Clothianidin (C)	8.31	459.33	/	/
					A:C＝50:1	32.06	119.06	107.05	111.22
A:C＝40:1	27.91	136.76	108.76	125.74
					A:C＝30:1	21.3	179.20	111.59	160.59
A:C＝20:1	20.8	183.51	117.11	156.70
					A:C＝15:1	18.55	205.77	122.46	168.03
A:C＝10:1	16.53	230.91	132.67	174.06
					A:C＝5:1	14.2	268.80	159.89	168.12

A:C＝3:1	12.17	313.64	189.83	165.22
					A:C＝1:1	8.50	449.06	279.66	160.57
A:C＝1:3	6.65	573.98	369.49	155.34
					A:C＝1:5	6.10	625.74	399.44	156.65
A:C＝1:10	5.87	650.26	426.66	152.41
					A:C＝1:15	5.53	690.24	436.87	158.00
A:C＝1:20	6.10	625.74	442.22	141.50
					A:C＝1:30	5.20	734.04	447.73	163.94
A:C＝1:40	6.60	578.33	450.56	128.36
					A:C＝1:50	6.81	560.50	452.28	123.93

Table 3 thiobenzamide and Diacloden mixture prevent and treat the Toxicity Determination result of rice fulgorid

Process	LC50(μg/ml)	ATI	TTI	CTC
					Thiobenzamide (A)	38.09	100.00	/	/
Diacloden (D)	69.12	55.11	/	/
					A:D＝50:1	30.26	125.88	99.12	126.99
A:D＝40:1	28.15	135.31	98.91	136.81
					A:D＝30:1	26.56	143.41	98.55	145.52
A:D＝20:1	23.48	162.22	97.86	165.77
					A:D＝14:1	23.06	165.18	97.01	170.27
A:D＝10:1	22.31	170.73	95.92	177.99
					A:D＝4:1	22.57	168.76	91.02	185.41
A:D＝2:1	21.30	178.83	85.04	210.30
					A:D＝1:1	24.71	154.15	77.55	198.76
A:D＝1:2	27.63	137.86	70.07	196.74
					A:D＝1:4	32.27	118.04	64.09	184.18
A:D＝1:10	35.85	106.25	59.19	179.51
					A:D＝1:14	38.20	99.71	58.10	171.62
A:D＝1:20	39.11	97.39	57.24	170.13
					A:D＝1:30	42.54	89.54	56.56	158.32
A:D＝1:40	46.73	81.51	56.20	145.03

A:D＝1:50

49.50

76.95

55.99

137.44

Table 4 thiobenzamide and Imidacloprid mixture prevent and treat the Toxicity Determination result of rice fulgorid

Process	LC50(μg/ml)	ATI	TTI	CTC
					Thiobenzamide (A)	38.16	100.00	/	/
Imidacloprid (E)	35.23	108.32	/	/
					A:E＝50:1	29.65	128.70	100.16	128.49
A:E＝40:1	27.21	140.24	100.20	139.96
					A:E＝30:1	25.08	152.15	100.27	151.75
A:E＝24:1	23.17	164.70	100.33	164.15
					A:E＝20:1	24.43	156.20	100.40	155.59
A:E＝10:1	22.06	172.98	100.76	171.68
					A:E＝4:1	19.60	194.69	101.66	191.51
A:E＝2:1	20.56	185.60	102.77	180.60
					A:E＝1:1	21.14	180.51	104.16	173.30
A:E＝1:2	19.81	192.63	105.54	182.51
					A:E＝1:4	20.75	183.90	106.65	172.43
A:E＝1:10	21.66	176.18	107.56	163.79
					A:E＝1:14	22.54	169.30	107.76	157.10
A:E＝1:20	23.19	164.55	107.92	152.48
					A:E＝1:30	23.42	162.94	108.05	150.80
A:E＝1:40	25.65	148.77	108.11	137.61
					A:E＝1:50	27.34	139.58	108.15	129.05

Table 5 thiobenzamide and cycloxaprid mixture prevent and treat the Toxicity Determination result of rice fulgorid

Process	LC50(μg/ml)	ATI	TTI	CTC
					Thiobenzamide (A)	37.99	100.00	/	/
Cycloxaprid (F)	0.35	10854.29	/	/
					A:F＝50:1	9.65	393.68	310.87	126.64
A:F＝40:1	7.33	518.28	362.30	143.05
					A:F＝30:1	5.85	649.40	446.91	145.31

A:F＝20:1	4.12	922.09	612.11	150.64
					A:F＝19:1	3.27	1161.77	637.71	182.18
A:F＝10:1	1.82	2087.36	1077.66	193.69
					A:F＝9:1	1.75	2170.86	1175.43	184.69
A:F＝4:1	0.98	3876.53	2250.86	172.22
					A:F＝1:1	0.43	8834.88	5477.14	161.30
A:F＝1:4	0.3	12663.33	8703.43	145.50
					A:F＝1:9	0.25	15196.00	9778.86	155.40
A:F＝1:10	0.26	14611.54	9876.62	147.94
					A:F＝1:15	0.27	14070.37	10182.14	138.19
A:F＝1:20	0.28	13567.86	10342.18	131.19
					A:F＝1:30	0.27	14070.37	10507.37	133.91
A:F＝1:40	0.28	13567.86	10591.99	128.10
					A:F＝1:50	0.29	13100.00	10643.42	123.08

Table 6 thiobenzamide and Nitenpyram mixture prevent and treat the Toxicity Determination result of rice fulgorid

Process	LC50(μg/ml)	ATI	TTI	CTC
					Thiobenzamide (A)	38.46	100.00	/	/
Nitenpyram (H)	8.82	436.05	/	/
					A:H＝50:1	27.36	140.57	106.59	131.88
A:H＝40:1	26.52	145.02	108.20	134.04
					A:H＝30:1	23.11	166.42	110.84	150.15
A:H＝24:1	22.25	172.85	113.44	152.37
					A:H＝20:1	20.78	185.08	116.00	159.55
A:H＝19:1	20.06	191.72	116.80	164.14
					A:H＝10:1	18.37	209.36	130.55	160.37
A:H＝9:1	17.61	218.40	133.61	163.47
					A:H＝4:1	12.75	301.65	167.21	180.40
A:H＝1:1	7.60	506.05	268.03	188.81
					A:H＝1:4	5.19	741.04	368.84	200.91
A:H＝1:9	4.88	788.11	402.45	195.83

A:H＝1:10	5.47	703.11	405.50	173.39
					A:H＝1:15	5.79	664.25	415.05	160.04
A:H＝1:20	5.81	661.96	420.05	157.59
					A:H＝1:30	5.90	651.86	425.21	153.30
A:H＝1:40	6.14	626.38	427.86	146.40
					A:H＝1:50	7.08	543.22	429.47	126.49

Table 7 thiobenzamide and imidaclothiz mixture prevent and treat the Toxicity Determination result of rice fulgorid

Process	LC50(μg/ml)	ATI	TTI	CTC
					Thiobenzamide (A)	38.7	100.00	/	/
Imidaclothiz (I)	37.3	103.75	/	/
					A:I＝50:1	31.2	124.04	100.07	123.95
A:I＝40:1	29.23	132.40	100.09	132.28
					A:I＝30:1	27.51	140.68	100.12	140.51
A:I＝20:1	25.46	152.00	100.18	151.73
					A:I＝10:1	22.37	173.00	100.34	172.41
A:I＝9:1	19.41	199.38	100.38	198.64
					A:I＝4:1	19.67	196.75	100.75	195.28
A:I＝1:1	21.43	180.59	101.88	177.26
					A:I＝1:4	22.96	168.55	103.00	163.64
A:I＝1:9	22.82	169.59	103.38	164.05
					A:I＝1:10	24.65	157.00	103.41	151.82
A:I＝1:14	25.20	153.57	103.50	148.37
					A:I＝1:20	26.06	148.50	103.57	143.38
A:I＝1:30	26.73	144.78	103.63	139.71
					A:I＝1:40	27.25	142.02	103.66	137.00
A:I＝1:50	29.68	130.39	103.68	125.76

Table 8 thiobenzamide and thiacloprid mixture prevent and treat the Toxicity Determination result of rice fulgorid

Process	LC50(μg/ml)	ATI	TTI	CTC
					Thiobenzamide (A)	38.8	100.00	/	/

Thiacloprid (J)	52.58	73.79	/	/
					A:J＝50:1	29.45	131.75	99.49	132.43
A:J＝40:1	26.37	147.14	99.36	148.08
					A:J＝30:1	23.16	167.53	99.15	168.96
A:J＝20:1	21.75	178.39	98.75	180.65
					A:J＝10:1	20.37	190.48	97.62	195.13
A:J＝9:1	21.41	181.22	97.38	186.10
					A:J＝3:1	23.62	164.27	93.45	175.78
A:J＝1:1	25.31	153.30	86.90	176.42
					A:J＝1:3	27.96	138.77	80.34	172.72
A:J＝1:9	30.23	128.35	76.41	167.97
					A:J＝1:10	29.85	129.98	76.17	170.64
A:J＝1:14	33.17	116.97	75.54	154.85
					A:J＝1:20	35.56	109.11	75.04	145.40
A:J＝1:30	35.97	107.87	74.64	144.52
					A:J＝1:40	37.44	103.63	74.43	139.23
A:J＝1:50	38.28	101.36	74.31	136.41

Toxicity Determination result table 1-table 8 shows, when water prevention rice fulgorid, thiobenzamide is that within the scope of 1:50 ~ 50:1, composite co-toxicity coefficient is greater than 120 with nicotinic insecticides such as MTI-446 at mass ratio respectively, has obvious synergistic function; Especially, when mass ratio is 1:30 ~ 30:1, synergistic effect is especially more outstanding.

Assays Example 2 prevents and treats black bean aphid activity test

Experimental technique: with reference to " NYT 1154.14-2008 farm-chemical indoor determination test rule insecticide the 14th part: leaf dipping method "

Table 9 thiobenzamide and Imidacloprid mixture are to black bean aphid toxicity test

Process	LC50(μg/ml)	ATI	TTI	CTC
					Thiobenzamide (A)	22.16	100.00	/	/
Imidacloprid (E)	10.29	215.35	/	/

A:E＝50:1	17.08	129.74	102.26	126.87
					A:E＝40:1	16.26	136.29	102.81	132.56
A:E＝30:1	15.12	146.56	103.72	141.30
					A:E＝20:1	14.84	149.33	105.49	141.55
A:E＝10:1	12.14	182.54	110.49	165.21
					A:E＝4.5:1	9.39	236.00	120.97	195.08
A:E＝1:1	8.11	273.24	157.68	173.29
					A:E＝1:4.5	6.77	327.33	194.38	168.39
A:E＝1:10	6.9	321.16	204.87	156.76
					A:E＝1:20	6.77	327.33	209.86	155.97
A:E＝1:30	7.16	309.50	211.63	146.24
					A:E＝1:40	7.39	299.86	212.54	141.09
A:E＝1:50	8.23	269.26	213.09	126.36

Table 10 thiobenzamide and Acetamiprid mixture are to black bean aphid toxicity test

Process	LC50(μg/ml)	ATI	TTI	CTC
					Thiobenzamide (A)	22.64	100.00	/	/
Acetamiprid (G)	19.65	115.22	/	/
					A:G＝50:1	17.53	129.15	100.30	128.77
A:G＝40:1	15.98	141.68	100.37	141.15
					A:G＝30:1	17.51	129.29	100.49	128.66
A:G＝20:1	16.15	140.17	100.72	139.16
					A:G＝10:1	15.33	147.73	101.38	145.71
A:G＝4:1	14.53	155.84	103.04	151.24
					A:G＝1:1	13.20	171.46	107.61	159.34
A:G＝1:4	12.17	186.03	112.17	165.84
					A:G＝1:10	13.23	171.10	113.83	150.31
A:G＝1:20	14.09	160.65	114.49	140.32
					A:G＝1:30	15.10	149.93	114.73	130.69
A:G＝1:40	14.87	152.25	114.85	132.57
					A:G＝1:50	15.24	148.56	114.92	129.27

Table 11 thiobenzamide and Nitenpyram mixture are to black bean aphid toxicity test

Process	LC50(μg/ml)	ATI	TTI	CTC
					Thiobenzamide (A)	22.74	100.00	/	/
Nitenpyram (H)	10.25	221.85	/	/
					A:H＝50:1	17.65	128.84	102.39	125.83
A:H＝40:1	17.59	129.28	102.97	125.55
					A:H＝30:1	13.36	170.21	103.93	163.77
A:H＝20:1	13.8	164.78	105.80	155.75
					A:H＝10:1	10.45	217.61	111.08	195.91
A:H＝2:1	9.17	247.98	140.62	176.35
					A:H＝1:1	9.39	242.17	160.93	150.49
A:H＝1:5	6.35	358.11	201.54	177.68
					A:H＝1:10	6.64	342.47	210.78	162.48
A:H＝1:20	6.57	346.12	216.05	160.20
					A:H＝1:30	6.23	365.01	217.92	167.49
A:H＝1:40	7.96	285.68	218.88	130.52
					A:H＝1:50	8.13	279.70	219.46	127.45

Toxicity Determination result table 9-table 11 shows, when preventing and treating black bean aphid, thiobenzamide is that within the scope of 1:50 ~ 50:1, composite co-toxicity coefficient is greater than 120 with the nicotinic insecticide such as Imidacloprid at mass ratio respectively, has obvious synergistic function; Especially, when mass ratio is 1:30 ~ 30:1, synergistic effect is especially more outstanding.

Field trial embodiment

In the following table, medicament thiobenzamide is referred to as sulfo-.

Contrast medicament

CK1:20% thiobenzamide wetting powder, self-control.

CK2:20% cycloxaprid wettable powder, self-control.

CK3:20% MTI-446 soluble granule, registration card number is LS20130077, Mitsui chemistry AGRO Co., Ltd..

CK4:20% clothianidin suspending agent, registration card number is LS20130279, Hebei Weiyuan Biochemical Co., Ltd..

CK5:25% Diacloden water dispersible granules, registration card number is PD20122066, Hailir Pharmaceutical Group Co., Ltd..

CK6:25% imidacloprid wettable powder, registration card number is PD20130581, Shandong Cao Da Chemical Co., Ltd..

CK7:40% acetamiprid water dispersible granules, registration card number is PD20131398, Guangdong Zhongxun Agricultural Technology Co., Ltd..

CK8:60% Nitenpyram wetting powder registration card number is PD20130674, Jiangsu Fengshan Group Co.

CK9:50% thiacloprid water dispersible granules, registration card number is LS20110019, Shaanxi Welch Crop Protection Co., Ltd..

CK10:40% imidaclothiz water dispersible granules, registration card number is PD20096024, Jiangshan Pesticides & Chemical Co., Ltd., Nantong of Jiangsu Province.

Experimental technique: with reference to " GB/T 17980.4-2000 pesticide field efficacy medicine test criterion (one) insecticide control water rice hopper ".Controlling object: rice fulgorid; Application method: conventional spraying.

Drug effect computational methods:

Result of the test: in Table 12-table 15 (data are the mean value repeated for 4 times in table)

Table 12 water prevention rice fulgorid field test results (one)

Result of the test table 12 shows, thiobenzamide respectively with MTI-446, clothianidin, Diacloden, Imidacloprid, cycloxaprid, Acetamiprid, thiacloprid composite water prevention rice fulgorid preventive effect is high and be all greater than 81%; Compared with single dose, the preventive effect after composite is higher than single dose more than 9%.

Table 13 water prevention rice fulgorid field test results (two)

Result of the test table 13 shows, thiobenzamide is effective with MTI-446, clothianidin, Thiamethoxam compound water prevention rice fulgorid respectively, and preventive effect is all greater than 85%; Compared with single dose, the preventive effect after composite is higher than single dose more than 13%.

Table 14 water prevention rice fulgorid field test results (three)

Result of the test table 14 shows, thiobenzamide is effective with MTI-446, clothianidin, Diacloden, Imidacloprid, cycloxaprid, Acetamiprid, Nitenpyram, thiacloprid, imidaclothiz composite water prevention rice fulgorid respectively, and the preventive effect after composite is all greater than 84%; Compared with single dose, the preventive effect after composite is higher than single dose more than 11%.

Table 15 water prevention rice fulgorid field test results (four)

Result of the test table 15 shows, thiobenzamide is effective with MTI-446, clothianidin, Diacloden, Imidacloprid, cycloxaprid composite water prevention rice fulgorid respectively, and the preventive effect after composite is all greater than 83%; Compared with single dose, the preventive effect after composite is higher than single dose more than 13%.

The compound synergic effect of the present composition, is not limited to the activity experiment listed by invention.Verified composition of the present invention, sucking pest control has broad application prospects, and particularly in rice fulgorid, thrips, aphid, two spotted spider mite control, effect is very outstanding.The present invention simultaneously also has good preventive effect to some lepidoptera pests, is a kind of insecticide of wide spectrum.In addition, the control efficiency of above-mentioned Pesticidal combination and preparation thereof 7d after medicine still can reach more than 85%, and the Pesticidal combination lasting period of the present invention is long.

Although the bromo-N-of reactive compound I 3-[4-chloro-2-methyl-6-(methylamino thioformyl) benzene]-1-(3-chloropyridine-2-base)-1H-pyrazoles-5-formamide and elite insecticidal active compound II are known compound in the present invention, above-mentioned reactive compound is composite is then non-obvious with the more outstanding insecticidal effect realized desired by the present invention for those skilled in the art.

Claims (10)

1. contain the Pesticidal combination of thiobenzamide and nicotinic insecticide; it is characterized in that: described Pesticidal combination is made up of thiobenzamide and nicotinic insecticide; described thiobenzamide is the bromo-N-of 3-[4-chloro-2-methyl-6-(methylamino thioformyl) benzene]-1-(3-chloropyridine-2-base)-1H-pyrazoles-5-formamide, and the weight ratio of described thiobenzamide and nicotinic insecticide is 1:50 ~ 50:1.

2. the Pesticidal combination containing thiobenzamide and nicotinic insecticide according to claim 1, is characterized in that: described nicotinic insecticide is any one in MTI-446, clothianidin, Diacloden, Imidacloprid, cycloxaprid, Acetamiprid, Nitenpyram, imidaclothiz or thiacloprid.

3. the Pesticidal combination containing thiobenzamide and nicotinic insecticide according to claim 2, is characterized in that: described nicotinic insecticide is any one in MTI-446, clothianidin, Diacloden, Imidacloprid.

4. the Pesticidal combination containing thiobenzamide and nicotinic insecticide according to claim 1,2 or 3, is characterized in that: the weight ratio of described thiobenzamide and nicotinic insecticide is 1:30 ~ 30:1.

5. an agricultural insecticide, is characterized in that: the Pesticidal combination containing thiobenzamide and nicotinic insecticide according to any one of claim 1-4 and auxiliary material form, and wherein, described Pesticidal combination accounts for 0.1% ~ 80% of described insecticidal total weight.

6. a kind of agricultural insecticide according to claim 5, is characterized in that: described Pesticidal combination accounts for 1% ~ 60% of described insecticidal total weight.

7. a kind of agricultural insecticide according to claim 6, is characterized in that: described Pesticidal combination accounts for 5% ~ 41% of described insecticidal total weight.

8. a kind of agricultural insecticide according to claim 5,6 or 7, is characterized in that: described insecticide can be mixed with seed treatment formulations, ultra low volume liquids, granule, missible oil, wetting powder, water dispersible granules or suspending agent.

9. the application of a kind of agricultural insecticide in controlling crop diseases and insect pests according to any one of claim 5-8.

10. the application of a kind of agricultural insecticide according to claim 9 in controlling crop diseases and insect pests, is characterized in that: the application of described agricultural insecticide on control rice fulgorid, thrips, aphid.