Summary of the invention
The technical problem to be solved in the present invention is, can not carry out the defect of Measurement accuracy, provide a kind of patella osteotomy method for three-dimensional measurement and system for existing method before patella bone-culting operation to the three-dimensional parameter of patella.
The technical solution adopted for the present invention to solve the technical problems is: construct a kind of patella osteotomy method for three-dimensional measurement, comprise the following steps:
S1, set up patella three-dimensional digitalization model based on the kneed medical image data of patient;
S2, import described patella three-dimensional digitalization model by reverse engineering software, and form new coordinate system based on patella Character adjustment co-ordinate system location, based on this new coordinate system, measure the three-dimensional parameter of patella;
S3, employing area of computer aided virtual technology, patella bone-culting operation in simulation total knee arthroplasty, carries out virtual osteotomy to patella;
The three-dimensional parameter of patella is remained after S4, measurement virtual osteotomy.
According in patella osteotomy method for three-dimensional measurement of the present invention, described step S1 is specially: imported the patient knee joint CT/MRI tomoscan image preserved in dicom format by medical image software, there is according to bone and soft tissue the feature of different gray value, carry out Iamge Segmentation and repairing, calculate and obtain patella three-dimensional digitalization model, and save as PLY form.
According in patella osteotomy method for three-dimensional measurement of the present invention, described step S2 specifically comprises:
S21, import described patella three-dimensional digitalization model by reverse engineering software, adopt selection tool to select patella frontal cortex surface, according to principle of least square method matching first plane, and select at patella central median ridge place create the first straight lines at 2;
S22, based on patella Character adjustment co-ordinate system location, make XY plane and described first planar registration, Y-axis and described first aligned, to form new coordinate system;
S23, based on this new coordinate system, measured the three-dimensional parameter of patella by constraint frame instrument.
According in patella osteotomy method for three-dimensional measurement of the present invention, described step S3 specifically comprises: by the clipping tool of reverse engineering software, select to cut out according to characteristic plane, the virtual osteotomy plane being parallel to described first plane generated is moved in parallel minimum point place, lateral articular face to patella along Z axis, to simulate patella bone-culting operation in total knee arthroplasty, virtual osteotomy rear enclosed osteotomy surface is carried out to patella.
According in patella osteotomy method for three-dimensional measurement of the present invention, described step S4 specifically comprises: the three-dimensional parameter remaining patella after measuring virtual osteotomy by the constraint frame instrument of reverse engineering software, comprises residue patella thickness, the width of osteotomy surface and length.
The present invention is also corresponding provides a kind of patella osteotomy three-dimension measuring system, comprising:
Model building module, for setting up patella three-dimensional digitalization model based on the kneed medical image data of patient;
Coordinate modification module, for being imported described patella three-dimensional digitalization model by reverse engineering software, and is formed new coordinate system based on patella Character adjustment co-ordinate system location, measures the three-dimensional parameter of patella based on this new coordinate system;
Virtual osteotomy module, for adopting area of computer aided virtual technology, patella bone-culting operation in simulation total knee arthroplasty, carries out virtual osteotomy to patella;
Osteotomy parameters measurement module, for remaining the three-dimensional parameter of patella after measuring virtual osteotomy.
According in patella osteotomy three-dimension measuring system of the present invention, described model building module sets up patella three-dimensional digitalization model based on the kneed medical image data of patient in the following manner: imported the patient knee joint CT/MRI tomoscan image preserved in dicom format by medical image software, there is according to bone and soft tissue the feature of different gray value, carry out Iamge Segmentation and repairing, calculate and obtain patella three-dimensional digitalization model, and save as PLY form.
According in patella osteotomy three-dimension measuring system of the present invention, described coordinate modification module specifically comprises:
Feature selection unit, for being imported described patella three-dimensional digitalization model by reverse engineering software, adopt selection tool to select patella frontal cortex surface, according to principle of least square method matching first plane, and select at patella central median ridge place create the first straight line at 2;
Coordinate Adjusting unit, for based on patella Character adjustment co-ordinate system location, make XY plane and described first planar registration, Y-axis and described first aligned, to form new coordinate system;
Patella parameter measurement unit, for measuring the three-dimensional parameter of patella based on this new coordinate system by constraint frame instrument.
According in patella osteotomy three-dimension measuring system of the present invention, described virtual osteotomy module carries out virtual osteotomy to patella in the following manner: by the clipping tool of reverse engineering software, select to cut out according to characteristic plane, the virtual osteotomy plane being parallel to described first plane generated is moved in parallel minimum point place, lateral articular face to patella along Z axis, to simulate patella bone-culting operation in total knee arthroplasty, virtual osteotomy rear enclosed osteotomy surface is carried out to patella.
According in patella osteotomy three-dimension measuring system of the present invention, described osteotomy parameters measurement module remains the three-dimensional parameter of patella after measuring virtual osteotomy by the constraint frame instrument of reverse engineering software, comprise residue patella thickness, the width of osteotomy surface and length.
Implement patella osteotomy method for three-dimensional measurement of the present invention and system, there is following beneficial effect:
1, the present invention utilizes computer virtual technology to provide a kind of technical scheme measured patella three-dimensional parameter and carry out virtual osteotomy, quantitative analysis can be carried out to patella three-dimensional configuration, and can the postoperative patella three-dimensional configuration of virtual operation accurate analysis be passed through, make surgical doctor can fully understand the patella form of this patient in the preoperative, implement " personalization " osteotomy, contribute to improving postoperative clinical effectiveness;
2, the perioperative three-dimensional data of patella virtual osteotomy that the present invention obtains can also be used to make patellar prosthesis, especially can carry out measure prostheses parameter according to the patella parameter of current patents, improves the matching degree of prosthese in operation;
3, for the irregular characteristic of patella, the feature that the present invention is based on patella adjusts co-ordinate system location, make the data measured more accurate, subjectivity operation in process is dropped to minimum on the impact of result, ensure the concordance of measurement result, prove that the measurement concordance of (ICC value 0.86 ~ 0.98) between (ICC value 0.80 ~ 0.99) and same observer between this measuring method different observers is higher by statistical test, can promote the use of.
Detailed description of the invention
In order to make object of the present invention, technical scheme and advantage clearly understand, below in conjunction with drawings and Examples, the present invention is further elaborated.
Patella osteotomy method for three-dimensional measurement of the present invention refers to and passes through computer means, measure the three-dimensional parameter of preoperative patella, such as patella width, length, thickness, the three-dimensional parameters such as facies articularis patellae width, length and central median ridge position, simultaneously by computer virtual means simulation patella bone-culting operation, determine osteotomy surface position, and the thickness to residue patella, the three-dimensional parameters such as the width of osteotomy surface and length are measured.
Referring to Fig. 1, is the flow chart of patella osteotomy method for three-dimensional measurement according to the preferred embodiment of the invention.As shown in Figure 1, the patella osteotomy method for three-dimensional measurement that this embodiment provides comprises the following steps:
1, in step sl, patella three-dimensional digitalization model is set up based on the kneed medical image data of patient.
Particularly, the present invention needs to obtain patient knee joint CT/MRI tomoscan image in advance.Subsequently, import this CT/MRI tomoscan image by medical image software, there is according to bone and soft tissue the feature of different gray value, carry out Iamge Segmentation and repairing, calculate and obtain patella three-dimensional digitalization model, and store for subsequent use.The medical image software adopted in the present invention can be Mimics 17.0 or other software of the same type.In a preferred embodiment of the invention, this step is realized based on medical image software Mimics 17.0, therefore in advance the patient knee joint CT/MRI tomoscan image of acquisition is preserved in dicom format, imported in medical image software Mimics 17.0 subsequently, obtain patella three-dimensional digitalization model after carrying out three-dimensional reconstruction, store for subsequent use with PLY form.
2, in step s 2, import patella three-dimensional digitalization model by reverse engineering software, and based on patella Character adjustment co-ordinate system location, set up new coordinate system, based on this new coordinate system, measure the three-dimensional parameter of patella.
The reverse engineering software adopted in the present invention can be Geomagic Studio 2014 or other software of the same type.Be illustrated in figure 2 the patella three-dimensional digitalization model schematic diagram imported by reverse engineering software Geomagic Studio 2014.In a preferred embodiment of the invention, realize this step based on Geomagic Studio2014, adjust co-ordinate system location based on patella feature, make the three-dimensional parameter recorded more meet the morphological characteristic of patella.The three-dimensional parameter of this patella comprises patella width, length, thickness, the three-dimensional parameters such as facies articularis patellae width, length and central median ridge position.
3, in step s3, adopt area of computer aided virtual technology, patella bone-culting operation in simulation total knee arthroplasty, carries out virtual osteotomy to patella.Fig. 3 is the schematic diagram by patella bone-culting operation in reverse engineering software simulation total knee arthroplasty.Particularly, can by the clipping tool of reverse engineering software, select to cut out according to characteristic plane, virtual osteotomy plane is represented with this characteristic plane generated, move in patella bone-culting operation the position needing to intercept, the i.e. position of facies articularis patellae, closes osteotomy surface, to realize virtual osteotomy after cutting out.In Fig. 3, the top of shadow representation is the patella part cut out from facies articularis patellae, and bottom is remaining patella part.
4, in step s 4 which, the three-dimensional parameter of patella is remained after measuring virtual osteotomy.For reverse engineering software Geomagic Studio 2014, the three-dimensional parameter of patella is remained after can measuring virtual osteotomy by the constraint frame instrument (bondingbox) of reverse engineering software, comprise residue patella thickness, the width of osteotomy surface and length.
Patella osteotomy method for three-dimensional measurement of the present invention, computer virtual technology is utilized to provide a kind of technical scheme measured patella three-dimensional parameter and carry out virtual osteotomy, the three-dimensional stereo model of patient can be set up by the medical image image of preoperative acquisition, on threedimensional model, morphometry and virtual patella osteotomy is carried out by reverse engineering software, thus the three-dimensional parameter of preoperative patella can be measured, utilize the clipping tool of reverse engineering software to cut out according to characteristic plane simultaneously, realize virtual osteotomy, and remain the three-dimensional parameter of patella after measuring osteotomy.Therefore, surgical doctor can fully understand the patella form of this patient in the preoperative, by osteotomy operation in virtual art, implements " personalization " osteotomy, remains the morphological indexes of patella, will contribute to improving postoperative clinical effectiveness after obtaining osteotomy.In addition, the perioperative three-dimensional data of patella virtual osteotomy that the present invention can also be utilized to obtain, to make patellar prosthesis, especially can carry out measure prostheses parameter according to the patella parameter of current patents, improves the matching degree of prosthese in operation.
Another original creation part of the present invention is to adjust co-ordinate system location based on the feature of patella, and the data making it measure are more accurate, and ensured the concordance of measurement result.Correspondingly, in another preferred embodiment of the invention, step S2 may further include following steps:
(1) first, in the step s 21, import patella three-dimensional digitalization model by reverse engineering software, adopt selection tool to select patella frontal cortex surface, according to principle of least square method matching first plane 2, and select create the first straight line 1 at 2 at patella central median ridge place.
Particularly, the patella three-dimensional digitalization model preserved with PLY form can be imported reverse engineering software Geomagic Studio 2014, selection tool is adopted to select patella frontal cortex surface, as the cambered surface region smoothly transitted below articular surface in the irregular patella model of Fig. 2.Can by the mutual region manually being selected place, patella frontal cortex surface by user of computer and user in the present invention, also can by the region at algorithm determination patella frontal cortex surface place of computer by carrying.Subsequently, according to principle of least square method, the method for least square plane fitting instrument as carried by reverse engineering software simulates the first plane 2.After least square fitting, this patella frontal cortex surface can be made to the square distance of this first plane 2 with for minimum.In this step, also need to select create the first straight line 1 at 2 at patella central median ridge place.
(2) subsequently, in step S22, based on patella Character adjustment co-ordinate system location, XY plane is alignd with the first plane 2, and Y-axis is alignd with the first straight line 1, to form new coordinate system.As in Fig. 2, the position of coordinate system is adjusted to XY plane parallel with the first plane 2, Y-axis is parallel with the first straight line 1.
(3) last, in step S23, based on this new coordinate system, measured the three-dimensional parameter of patella by constraint frame instrument (bondingbox), comprise patella width, length, thickness, the three-dimensional parameters such as facies articularis patellae width, length and central median ridge position.
At present, when using computer virtual technology to carry out the three-dimensional dimension of Measuring Object model, especially time for irregularly shaped object, usually rule of thumb subjectively select coordinate system by operator, and co-ordinate system location difference will make the data such as length, width and the height measured different.For patella model, if select coordinate system by operator's subjectivity, final patella three-dimensional parameter measurement result also can be made to there is larger randomness.Although selected patella frontal cortex surface link to there is subjectivity by selection tool in the present invention, may difference be there is in the patella frontal cortex surface that namely different personnel choose, but the present invention can overcome this problem by the method for adjustment of subsequent coordinates system, and drops to minimum by the difference of last measurement result.
The present invention is by randomly drawing 20 routine patellas in digitized bone bank, three-dimensional measurement is carried out by two independent doctors, obtain respectively build width, length, the thickness of patella model, the thickness of patella is remained, the parameters such as osteotomy surface width, length after facies articularis patellae width, length and central median ridge position and virtual osteotomy; In addition, by wherein doctor at interval the above-mentioned parameter of the routine patella of repeated measure 20 after month, it is 0.80 ~ 0.99 that statistical method records ICC between different observers (interclass correlation coefficient) value, between same observer, ICC value is 0.86 ~ 0.98, prove that the concordance that measuring method of the present invention is measured is higher thus, can promote the use of.
Correspondingly, determine in the present invention that the method for virtual osteotomy plane also improves the accuracy of virtual osteotomy operation.In a preferred embodiment of the invention, can by the clipping tool of reverse engineering software in step S3, select to cut out according to characteristic plane, and the virtual osteotomy plane being parallel to the first plane 2 generated is moved in parallel minimum point place, lateral articular face to patella, i.e. virtual osteotomy plane 3 in Fig. 3 along Z axis.Based on the determined virtual osteotomy plane 3 of new coordinate system, be located substantially on the articular surface position of patella, ensure that the precision that virtual osteotomy is performed the operation.
The present invention is also corresponding provides a kind of patella osteotomy three-dimension measuring system.Referring to Fig. 4, is the module diagram of patella osteotomy three-dimension measuring system according to the present invention.As shown in Figure 4, this patella osteotomy three-dimension measuring system 100 comprises: model building module 10, coordinate modification module 20, virtual osteotomy module 30 and osteotomy parameters measurement module 40.
Wherein, model building module 10 is for setting up patella three-dimensional digitalization model based on the kneed medical image data of patient.This model building module 10 based on medical image software simulating, can include but not limited to Mimics 17.0.Particularly, in advance the patient knee joint CT/MRI tomoscan image of acquisition is preserved in dicom format, obtained by the model building module 10 based on medical image software Mimics 17.0 subsequently and import this DICOM formatted file, there is according to bone and soft tissue the feature of different gray value, carry out Iamge Segmentation and repairing, calculate and obtain patella three-dimensional digitalization model, and store for subsequent use with PLY form.
Coordinate modification module 20 for importing patella three-dimensional digitalization model by reverse engineering software, and forms new coordinate system based on patella Character adjustment co-ordinate system location, measures the three-dimensional parameter of patella, as shown in Figure 2 based on this new coordinate system.This coordinate modification module 20 can realize based on reverse engineering software, includes but not limited to Geomagic Studio 2014.The three-dimensional parameter of the patella measured in this step comprises patella width, length, thickness, the three-dimensional parameters such as facies articularis patellae width, length and central median ridge position.
Virtual osteotomy module 30 is for adopting area of computer aided virtual technology, and patella bone-culting operation in simulation total knee arthroplasty, carries out virtual osteotomy to patella.This virtual osteotomy module 30 also can realize based on reverse engineering software, includes but not limited to Geomagic Studio 2014.Particularly, virtual osteotomy module 30 can by the clipping tool of reverse engineering software, select to cut out according to characteristic plane, virtual osteotomy plane is represented with this characteristic plane generated, move in patella bone-culting operation the position needing to intercept, i.e. the position of facies articularis patellae, after cutting out, close osteotomy surface, to realize virtual osteotomy, specifically as shown in Figure 3.
Osteotomy parameters measurement module 40 is for remaining the three-dimensional parameter of patella after measuring virtual osteotomy.This osteotomy parameters measurement module 40 also can realize based on reverse engineering software, includes but not limited to GeomagicStudio 2014.Osteotomy parameters measurement module 40 remains the three-dimensional parameter of patella after can measuring virtual osteotomy by the constraint frame instrument (bonding box) of reverse engineering software, comprise residue patella thickness, the width of osteotomy surface and length.
In another preferred embodiment of the invention, coordinate modification module 10 specifically comprises: feature selection unit, Coordinate Adjusting unit and patella parameter measurement unit.
Wherein feature selection unit is used for importing patella three-dimensional digitalization model by reverse engineering software, selection tool is adopted to select patella frontal cortex surface, according to principle of least square method matching first plane 2, and select create the first straight line 1 at 2 at patella central median ridge place.Particularly, the patella three-dimensional digitalization model preserved with PLY form can be imported reverse engineering software Geomagic Studio 2014, selection tool is adopted to select patella frontal cortex surface, as the cambered surface region smoothly transitted below articular surface in the irregular patella model of Fig. 2.The patella frontal cortex surface data that this Coordinate Adjusting unit manually can be selected by user by the mutual reception of computer and user, also can by the algorithm determination patella frontal cortex surface of computer by carrying.Subsequently, according to principle of least square method, the method for least square plane fitting instrument as carried by reverse engineering software simulates the first plane 2.After least square fitting, this patella frontal cortex surface can be made to the square distance of this first plane 2 with for minimum.Feature selection unit can also select create the first straight line 1 at 2 at patella central median ridge place according to the input of user or the algorithm carried.
Coordinate Adjusting unit is used for based on patella Character adjustment co-ordinate system location, and XY plane is alignd with the first plane 2, and Y-axis is alignd with the first straight line 1, to form new coordinate system.As in Fig. 2, the position of coordinate system is adjusted to XY plane parallel with the first plane 2, Y-axis is parallel with the first straight line 1.
Patella parameter measurement unit is used for the three-dimensional parameter being measured patella based on this new coordinate system by constraint frame instrument (bondingbox), comprise patella width, length, thickness, the three-dimensional parameters such as facies articularis patellae width, length and central median ridge position.
Correspondingly, determine in the present invention that the method for virtual osteotomy plane also improves the accuracy of virtual osteotomy operation.In a preferred embodiment of the invention, virtual osteotomy module 30 can by the clipping tool of reverse engineering software, select to cut out according to characteristic plane, and the virtual osteotomy plane being parallel to the first plane 2 generated is moved in parallel minimum point place, lateral articular face to patella, i.e. virtual osteotomy plane 3 in Fig. 3 along Z axis.Based on the determined virtual osteotomy plane 3 of new coordinate system, be located substantially on the articular surface position of patella, ensure that the precision that virtual osteotomy is performed the operation.
Therefore, patella osteotomy three-dimension measuring system 100 of the present invention can be combined by soft and hardware and realize.This system can pass through permanent computer readable medium and/or storage medium, and/or permanent machine readable medium and/or storage medium realize, the machine code that they store and/or computer program comprise at least one code segment, at least one code segment described is performed by machine and/or computer, thus makes this machine and/or computer perform the step of above-mentioned patella osteotomy three-dimensional measurement.The present invention can also be realized by computer system.The present invention can realize in a centralised manner at least one computer system, or is realized by the different piece be distributed in the computer system of several interconnection with a scattered manner.Any can computer system to implement the methods or miscellaneous equipment be all applicatory.The combination of conventional software and hardware can be the general-purpose computing system being provided with computer program.The present invention can also be embedded into computer program and implement, and program package, containing whole features that can realize method of the present invention, when it is installed in computer system, can realize these methods of the present invention.
It should be appreciated that, patella osteotomy method for three-dimensional measurement of the present invention is identical with implementation with the principle of system, is therefore also adapted to patella osteotomy three-dimension measuring system of the present invention to the specific descriptions of patella osteotomy method for three-dimensional measurement embodiment in the present invention.
The present invention is described according to specific embodiment, but it will be understood by those skilled in the art that when not departing from the scope of the invention, can carry out various change and equivalent replacement.In addition, for adapting to specific occasion or the material of the technology of the present invention, can many amendments be carried out to the present invention and not depart from its protection domain.Therefore, the present invention is not limited to specific embodiment disclosed herein, and comprises all embodiments dropping into claims.