CN104510447A - Visible light and near-infrared light sublingual image acquisition system - Google Patents

Visible light and near-infrared light sublingual image acquisition system Download PDF

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CN104510447A
CN104510447A CN201510016921.1A CN201510016921A CN104510447A CN 104510447 A CN104510447 A CN 104510447A CN 201510016921 A CN201510016921 A CN 201510016921A CN 104510447 A CN104510447 A CN 104510447A
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sublingual
image
tongue
circuit board
image acquisition
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闫子飞
沈毅
张大鹏
李乃民
朱焕超
丁皓伦
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Harbin Institute of Technology
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0033Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room
    • A61B5/004Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room adapted for image acquisition of a particular organ or body part
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0075Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/48Other medical applications

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Abstract

The invention discloses a visible light and near-infrared light sublingual image acquisition system, belongs to the technical field of sublingual images, and aims to solve the problems of poor signal quality, limited effective information and difficult standardization of image signal processing for a sublingual image obtained by existing equipment. The system is characterized in that a left supporting plate, a right supporting plate, an upper supporting plate, a lower supporting plate and a rear back plate define a cuboid cavity; a light source module and a video camera module are arranged in the cuboid cavity; the opening end of the cuboid cavity serves as a test end; the test end is opposite to the end surface of the rear back plate; a pair of parallel grooves are formed in the positions, close to the lower supporting plate, of the inner side surfaces of the left supporting plate and the right supporting plate, and inner insertion plates are inserted and fixed in the grooves; a display is arranged on the upper supporting plate and close to one side of the rear back plate. The system is used for acquiring the visible light and near-infrared light sublingual image.

Description

Visible ray and near infrared light Sublingual image capturing system
Technical field
The present invention relates to visible ray and near infrared light Sublingual image capturing system, belong to image technique field, Sublingual.
Background technology
The internal organs that tongue uniquely exposes as human body, see it and resemble the overall health that can reflect human body, can disclose again the local patholoic change of human five internal organs's six internal organs, sometimes even can also find the pathological changes that the modern medical equipments such as B ultrasonic, CT, nuclear magnetic resonance, NMR can not check out.
In recent years, along with the modernization of inspection of the tongue, the particularly modernization of tongue reconstruction detecting instrument, picture of the tongue both domestic and external particularly obtains for the quantitative research work of lingual surface image aspect to be carried out widely.Extract at tongue image collecting device, picture of the tongue quantization characteristic, all achieve certain achievement based in the picture of the tongue diagnosis of quantization characteristic and the foundation of inspection of the tongue system etc.But, at present to the important component part of Evolution of Tongue Inspection of TCM---the quantitative research of the sublingual vessel diagnostic method is carried out also considerably less.
For portal hypertension, as a kind of Comprehensive Clinical performance of portal vein circulatory disturbance caused by many reasons, the method of current doctor trained in Western medicine clinical evaluation portal venous pressure is mainly the invasive methods of traditional digital subtraction angiography, but because it is greatly traumatic, technical requirement is high, and patient's factors such as large and complication is many by quantity of X-rays X make it be difficult to as routine examination.And in the traditional Chinese medical science sublingual vessel diagnostic method, according to the expansion of tongue vascular footpath, morphologic change, color, dark violet and patient has the information of hepatitis history, namely should diagnose and suffer from portal hypertension.In addition, tongue arteries and veins is upheld and is changed in arachnoid beading sample, and color is dark reddish purple cough and asthma medical history, namely should be thought of as pulmonary heart disease; Tongue arteries and veins extends pinniform collateral formation, has ecchymosis petechia, color red or pale purple, with sensation of oppression over the chest with shortness of breath and blood pressure rising person, is thought of as hypertension more.Three kinds of diseases, because its pathomechanism is different, its sublingual vessel lesion degree produced is had nothing in common with each other, and illustrates further, and in some disease, observe bottom tongue, i.e. sublingual area, has important dialectical differential diagnosis of diseases meaning, is worth applied research.
In recent years, the research that objectifies of the sublingual vessel diagnostic method has caused the attention of numerous scholar gradually, but be all be main acquisition target with tongue upper surface due to most of existing inspection of the tongue image acquisition instrument, compared to the lingual surface region stretching out oral cavity and open larger area, the required diagnostic characteristic such as sublingual vein, Sublingual vegetation observed of the sublingual vessel diagnostic method is all positioned at and cannot stretches out oral cavity and bottom the less tongue of area.Therefore, apply Sublingual image-region in the image that existing inspection of the tongue image acquisition instrument obtains very little, by Sublingual quality of image signals and comprise the restriction of the aspects such as effective information, great majority still rest on the extraction stage of sublingual vein being carried out to preliminary contours extract and rough diagnostic characteristic for the research of sublingual area.The defect of Sublingual this data source of picture signal causes the diagnostic characteristic in the sublingual vessel diagnostic method to be difficult to standardization, quantification, more need not carry and Sublingual feature application being diagnosed a disease in clinical.Therefore, the research that objectifies of the sublingual vessel diagnostic method must carry out brand-new exploration from the Sublingual Image Acquisition strategy stage, and then seek the solution of carrying out the feature extraction of multiple Sublingual and quantification for standardization Sublingual image, the Sublingual feature finally quantized in conjunction with the application of traditional Chinese medical science sublingual vessel diagnostic method theory carries out medical diagnosis on disease.
Summary of the invention
It is poor to the present invention seeks to solve the Sublingual quality of image signals adopting existing equipment to obtain, and it is limited to include effective information, and picture signal process is difficult to standardized problem, provides a kind of visible ray and near infrared light Sublingual image capturing system.
Visible ray of the present invention and near infrared light Sublingual image capturing system, it comprises shell, light source module, camara module and display,
Shell is made up of left support plate, right support plate, upper backup pad, lower supporting plate, postnotum and built-in inserted plate,
Left support plate, right support plate, upper backup pad, lower supporting plate and postnotum surround a cuboid cavity, in this cuboid cavity, light source module and camara module are set, the opening of cuboid cavity is as test lead, and this test lead is relative with postnotum place end face; The inner surface of left support plate and right support plate arranges near the position of lower supporting plate correspondence the groove be parallel to each other for a pair, and built-in inserted plate grafting is fixed in groove; Display is arranged on upper backup pad, and near postnotum side;
Light source module comprises circuit board, near-infrared LED, electric filament lamp, four fans, fin and Switching Power Supplies, circuit board is fixedly installed on the opening of cuboid cavity, cuboid cavity is divided into the test space and image acquisition space, image acquisition space is the length space between circuit board and postnotum; The center of circuit board arranges image acquisition through hole, circuit board on the surface in image acquisition space, fin is set, the position at fin four angles arranges a fan respectively; The outer surface of circuit board has near-infrared LED along the circumferential uniform welding of image acquisition through hole, and the bezel locations all round of circuit board outer surface arranges an electric filament lamp respectively; Switching Power Supply is arranged in image acquisition space, for providing working power for near-infrared LED, electric filament lamp, fan and display;
Camara module comprises 2CCD industrial camera, near-infrared camera lenses, base and switch, base and switch configuration are on the built-in inserted plate in image acquisition space, 2CCD industrial camera is fixed on base, 2CCD industrial camera is rotary with near-infrared camera lenses, near-infrared camera lenses stretches out image acquisition through hole, and the photocentre of near-infrared camera lenses and circuit board image gather the center conllinear of through hole; 2CCD industrial camera is via the network interface transmission data of switch;
Switching Power Supply is also for providing working power for 2CCD industrial camera.
At the opening of cuboid cavity, the edge of upper backup pad has a downward inclined plane, and the bottom center of this inclined plane has a nose outline curved support mouth.
Left support plate and right support plate arrange louvre respectively.
Circuit board is aluminium base circuit board.
2CCD industrial camera has GigE and transmits network interface, and this GigE transmits network interface and is connected with the network interface of switch, and transmits data.
Advantage of the present invention: present system is intended to for the research that objectifies of the sublingual vessel diagnostic method provides the Sublingual image catching Sublingual diagnostic characteristic as much as possible, due to sublingual vein because its physiological characteristics makes cannot intactly to be showed in the image of colored Sublingual, can the principle of blur-free imaging under near-infrared light source environment according to vein, The present invention gives the equipment solution that simultaneously can gather colored Sublingual image and near-infrared Sublingual image, while the imaging effect obtaining reaction sublingual vein physiological characteristics, also other tongue characteristics of sublingual vein are comprised under catching visible light environment.
Present system obtains clear picture, and comprises the whole Sublingual information needed for the diagnosis of tongue picture, is conducive to the standardization of picture signal process.
Accompanying drawing explanation
Fig. 1 is the internal structure schematic diagram of visible ray of the present invention and near infrared light Sublingual image capturing system;
Fig. 2 is an orientation three-dimensional structure diagram of the exterior contour of visible ray and near infrared light Sublingual image capturing system;
Fig. 3 is another orientation three-dimensional structure diagram of the exterior contour of visible ray and near infrared light Sublingual image capturing system;
Fig. 4 is the schematic diagram of camara module;
Fig. 5 is the side schematic surface of light source module;
Fig. 6 is the opposite side schematic surface of light source module;
Fig. 7 is ventral surface of tongue contour extraction method flow chart in the image of colored Sublingual;
Fig. 8 is excrescent extracting method flow chart in the image of colored Sublingual;
Fig. 9 is the extracting method flow chart of sublingual vein profile in the image of near-infrared Sublingual;
Figure 10 is the processing procedure overview flow chart of the image that present system obtains.
Detailed description of the invention
Detailed description of the invention one: present embodiment is described below in conjunction with Fig. 1 to Fig. 6, visible ray described in present embodiment and near infrared light Sublingual image capturing system, it comprises shell, light source module, camara module and display 4,
Shell is made up of left support plate 11, right support plate 12, upper backup pad 13, lower supporting plate 14, postnotum 16 and built-in inserted plate 15,
Left support plate 11, right support plate 12, upper backup pad 13, lower supporting plate 14 and postnotum 16 surround a cuboid cavity, in this cuboid cavity, light source module and camara module are set, the opening of cuboid cavity is as test lead, and this test lead is relative with postnotum 16 place end face; The inner surface of left support plate 11 and right support plate 12 arranges near the position of lower supporting plate 14 correspondence the groove be parallel to each other for a pair, and built-in inserted plate 15 grafting is fixed in groove; Display 4 is arranged on upper backup pad 13, and near postnotum 16 side;
Light source module comprises circuit board 21, near-infrared LED 22, electric filament lamp 23, four fans 24, fin 25 and Switching Power Supplies 26, circuit board 21 is fixedly installed on the opening of cuboid cavity, cuboid cavity is divided into the test space and image acquisition space, image acquisition space is the length space between circuit board 21 and postnotum 16; The center of circuit board 21 arranges image acquisition through hole, circuit board 21 on the surface in image acquisition space, fin 25 is set, the position at fin 25 4 angles arranges a fan 24 respectively; The outer surface of circuit board 21 has near-infrared LED 22 along the circumferential uniform welding of image acquisition through hole, and the bezel locations all round of circuit board 21 outer surface arranges an electric filament lamp 23 respectively; Switching Power Supply 26 is arranged in image acquisition space, for providing working power for near-infrared LED 22, electric filament lamp 23, fan 24 and display 4;
Camara module comprises 2CCD industrial camera 31, near-infrared camera lenses 32, base 33 and switch 34, base 33 and switch 34 are arranged on the built-in inserted plate 15 in image acquisition space, 2CCD industrial camera 31 is fixed on base 33,2CCD industrial camera 31 is rotary with near-infrared camera lenses 32, near-infrared camera lenses 32 stretches out image acquisition through hole, the photocentre of near-infrared camera lenses 32 and the center conllinear of circuit board 21 image acquisition through hole; 2CCD industrial camera 31 is via the network interface transmission data of switch 34;
Switching Power Supply 26 is also for providing working power for 2CCD industrial camera 31.
The data transmitted via the network interface of switch 34 comprise colored Sublingual image and the near-infrared Sublingual image that 2CCD industrial camera 31 gathers acquisition; The colored Sublingual image that 2CCD industrial camera 31 collection obtains passes to computer by switch 34, then passes to display 4 by computer and show.
Owing to needing gathered person retroflects body when gathering Sublingual image, demonstrate out the diagnostic characteristic of sublingual area and leave standstill a moment, image effect clearly could be obtained.But because the tongue body of people often slightly trembles, if application different cameras gathers colored Sublingual image and the near-infrared Sublingual image of same gathered person respectively, the two kinds of Sublingual images obtained can present notable difference, are unfavorable for the comparison and analysis of follow-up feature of the same race.In addition, if adopt color video camera and near-infrared video camera two cameras to gather Sublingual image simultaneously, although the state of same tongue body at synchronization can be captured, need the more problems considered, as the 1. position of two video cameras and the position arrangement of respective sources; 2. when obtaining dissimilar image, the handover mechanism of video camera and corresponding light source; 3. the position deviation owing to using two video cameras to produce, needs the image to obtaining to carry out image registration etc.This all can cause equipment complexity greatly to increase, and the volume of equipment also significantly increases.
Therefore, present embodiment adopts the 2CCD video camera of JAI company, gathers the light spectrum image-forming image of visible ray and near infrared light simultaneously, and exported via two transmission channels by two kinds of images simultaneously under same optical aperture.The coloured image be converted to by Bayer under a passage exports visible light conditions; Another passage exports the monochrome image under near infrared light condition.
The two-way view data that in camara module, switch is used for 2CCD industrial camera obtains spreads out of.Because the present invention need gather colored with near-infrared two kinds of images simultaneously, therefore, what require the camera lens of video camera to have visible ray and near infrared light is dual by property, selects here and retains the near-infrared camera lenses of visible ray by property.The data exported by switch finally input computer and carry out image procossing, realize two groups of image sequence transmission captured by 2CCD camera on computer.
The colored Sublingual image sequence that display is mainly used in camera to catch shows in real time, enables gathered person see the shooting situation of oneself tongue body, adjusts with auxiliary gathered person the attitude that lolls.Herein the video source of display be the video flowing that forms of the colored Sublingual image sequence in the two-path video source that obtains of computer terminal through device housings video input port transmission to the imaging on liquid crystal display.
Switching Power Supply and switch are controlled by facility switching, and equipment outer end adopts 220V mains-supplied.
Detailed description of the invention two: present embodiment is described below in conjunction with Fig. 2 and Fig. 3, present embodiment is described further embodiment one, at the opening of cuboid cavity, the edge of upper backup pad 13 has a downward inclined plane, and the bottom center of this inclined plane has a nose outline curved support mouth.
Present embodiment is the head of fixing gathered person, and can keep more consistent head pose when gathered person is lolled, upper backup pad near gathered person one end specialized designs one smooth and meet the nose supported design of nose outline.
Detailed description of the invention three: present embodiment is described below in conjunction with Fig. 1 to Fig. 3, present embodiment is described further embodiment one or two, and left support plate 11 and right support plate 12 arrange louvre respectively.
Due to more heat release assemblies such as using light source, video camera, Switching Power Supplies in present system, therefore, left support plate 11 and right support plate 12 are provided with two groups of louvres respectively.
Detailed description of the invention four: present embodiment is described further embodiment one, two or three, circuit board 21 is aluminium base circuit board.
Because the thermal discharge when continuous firing of two kinds of light sources in light source module is larger, common glass PCB cannot load its work long hours, therefore need to select the aluminium base with better heat sinking function, coordinate the heat abstractor such as fan, fin simultaneously, the heat that components and parts are sent more effectively is transmitted on fin, be dispersed in surrounding air through fin again, four groups of louvres on cooperating equipment shell, fan is utilized to be discharged from device interior by the amount of heat that the assembly such as light source, video camera produces in time, the normal operation of effective maintenance equipment.
Detailed description of the invention five: present embodiment is described further embodiment one, two, three or four, 2CCD industrial camera 31 has GigE and transmits network interface, and this GigE transmits network interface and is connected with the network interface of switch 34, and transmits data.
Below in conjunction with Fig. 7 to Figure 10, the processing procedure of the image that present system collection obtains is described:
Sublingual vessel diagnosis multispectral Sublingual image characteristic extracting method, this image extraction method gathers visible ray and near infrared light Sublingual image capturing system simultaneously and obtains colored Sublingual image and near-infrared Sublingual image extracts, and described image extraction method comprises the extraction of sublingual vein profile in excrescent extraction and near-infrared Sublingual image in the extraction of ventral surface of tongue profile in the image of colored Sublingual, colored Sublingual image;
Wherein in the image of colored Sublingual, the extracting method of ventral surface of tongue profile is:
First the interference of shade and tooth regions in the image of colored Sublingual is removed: be Lab pattern by the color space of colored Sublingual image by RGB patten transformation, extract a component in the image of Lab pattern color Sublingual, and histogram equalization process is carried out to it, to strengthen shade and the tooth regions contrast relative to ventral surface of tongue region; Again by thresholding process, in separation a component, chromatic value is lower than the pixel of preset value, and this pixel is judged to be interference region pixel, then set to 0 in the image of original color Sublingual with the rgb value of described pixel opposite position, the interference realizing shade and tooth regions in the image of colored Sublingual is removed, and obtains ventral surface of tongue region;
Then coarse segmentation is carried out to the ventral surface of tongue region obtained: adopt the method based on histogram contrast to obtain the Saliency maps of colored Sublingual image, through extracting and screening, the shadow band with most highly significant is isolated in Saliency maps, obtain the minimum enclosed rectangle comprising ventral surface of tongue region, and using the initialization border of this minimum enclosed rectangle as GrabCut, the inside of described minimum enclosed rectangle is as the possible prospect comprising ventral surface of tongue region, and outside is as the background in ventral surface of tongue region; Adopt GrabCut algorithm to carry out GrabCut auto Segmentation to described ventral surface of tongue region again, obtain the ventral surface of tongue candidate region after coarse segmentation;
Again secondary splitting is carried out to the ventral surface of tongue candidate region after coarse segmentation: adopt the method based on histogram contrast to obtain the Saliency maps of the ventral surface of tongue candidate region after coarse segmentation, thresholding method is adopted to remove low marking area in the Saliency maps of ventral surface of tongue candidate region, obtain the minimum enclosed rectangle in largest connected region in the Saliency maps of ventral surface of tongue candidate region, the minimum enclosed rectangle applying this largest connected region initializes GrabCut algorithm, GrabCut auto Segmentation is carried out to the ventral surface of tongue candidate region after coarse segmentation, obtain ventral surface of tongue profile in the image of colored Sublingual,
In the image of colored Sublingual, excrescent extracting method is:
First detection was carried out to the retroreflective regions of colored Sublingual image: thresholding is carried out in the region that the ventral surface of tongue profile obtained in the extracting method of ventral surface of tongue profile in the image of colored Sublingual surrounds, the weight increasing high luminance value regions when retroreflective regions threshold value is chosen is carried out in this thresholding process, in the region surround ventral surface of tongue profile, highlight regions is rejected completely, then the image repair method based on Fast Marching is used to carry out area filling to disallowable highlight regions, obtain the Sublingual vegetation image effect figure that Sublingual vegetation and body of the tongue vision difference increase, described body of the tongue is other region in the region of ventral surface of tongue profile encirclement except the vegetation of Sublingual,
Then coarse segmentation is carried out to Sublingual vegetation image effect figure: use multi thresholds Da-Jin algorithm to find best trough between the histogrammic adjacent peaks of Sublingual vegetation image effect figure, vegetation in the vegetation image effect figure of Sublingual to be separated with body of the tongue, obtain the excrescent coarse segmentation image in Sublingual;
Again Sublingual excrescent coarse segmentation image is carried out to the rejecting in vegetation region, non-Sublingual: use geometric measures to screen out, excrescent for Sublingual coarse segmentation image is carried out shade morphological dilations process among a small circle, if expansion results does not overlap with shade among a small circle, then determine this among a small circle shadow region be non-vegetation region, and non-vegetation region is rejected, obtain the vegetation region retained;
The edge in the vegetation region of reservation is superimposed upon in the image of described colored Sublingual, obtains final vegetation and extract image;
In the image of near-infrared Sublingual, the extracting method of sublingual vein profile is:
First near-infrared Sublingual image is carried out to the extraction of ventral surface of tongue profile: the ventral surface of tongue contour edge pixel position obtained in the extracting method according to ventral surface of tongue profile in the image of colored Sublingual, in the image of near-infrared Sublingual, determine ventral surface of tongue contour area, extract the ventral surface of tongue contour images obtaining near-infrared Sublingual image;
Then reflective spot in the ventral surface of tongue contour images of near-infrared Sublingual image is removed: the gray-value variation scope determining reflective spot region in the statistic histogram of this ventral surface of tongue contour images, reflective spot region is rejected by thresholding method, re-use 8-neighborhood minimum method and fill disallowable reflective spot region, and gray scale morphology opening operation is carried out to the pixel that 8-neighborhood is reflective spot, other reflective spot region in further elimination statistic histogram, obtains the sublingual vein profile preliminary images of near-infrared Sublingual image;
Extract candidate's sublingual vein area image again: the initial threshold μ being obtained the sublingual vein profile preliminary images of near-infrared Sublingual image by the method for statistics with histogram, and according to this initial threshold, sublingual vein profile preliminary images pixel is divided into A, B two regions, calculating the pixel grey scale average obtaining region A is μ 1, the pixel grey scale average of region B is μ 2, then calculate and obtain all pixels in A, B two regions and divide and be clipped to μ 1, μ 2euclidean distance d 1, d 2, and all adopt binaryzation method to be set to 0 and 255 pixel in A, B two regions:
d i = | f ( x , y ) - μ i ‾ | i = 1,2 ,
f ( x , y ) = 255 d 1 < d 2 0 d 2 < d 1 ;
In formula, f (x, y) represents the coordinate figure of all pixels in A, B two regions;
Obtain the sublingual vein image after binaryzation thus;
Again morphologic filtering denoising is used to the sublingual vein image after binaryzation, adopt the method for the first iteration corrosion of variable corrosion to ask for candidate's sublingual vein area image;
Finally extract and obtain sublingual vein contour images in the image of near-infrared Sublingual: the seed points determined in the method according to the first iteration corrosion of variable corrosion, based on sublingual vein profile preliminary images, use region-growing method, when the gray value differences of the pixel corresponding to sublingual vein profile preliminary images when the current pixel point being in candidate's sublingual vein area image is less than predetermined threshold, judge that current pixel point is as sublingual vein area pixel point, until when the pixel that adjacent two secondary growths increase is less than setting threshold value, growth course terminates, the region that thus obtained all sublingual vein area pixel points are formed is sublingual vein contour images in the image of near-infrared Sublingual,
Again the contour edge of this sublingual vein contour images is added in the image of colored Sublingual, obtains the sublingual vein profile in the image of colored Sublingual;
In the colored Sublingual image of above-mentioned acquisition, in ventral surface of tongue profile, colored Sublingual image, vegetation extracts image, sublingual vein profile in the image of near-infrared Sublingual in sublingual vein contour images and colored Sublingual image diagnoses for sublingual vessel jointly.
The concrete grammar of the excrescent coarse segmentation image in described acquisition Sublingual is:
First, make { 0,1,2 ..., 255} represents 256 gray levels of Sublingual vegetation image effect figure, and according to the grey level histogram of Sublingual vegetation image effect figure, check the minimum adjacent with maximum, when two minimums are all greater than given threshold value when about maximum, judge that this maximum is as an independent peak; Otherwise this maximum is compared with a previous or rear maximum, chooses maximum maximum as peak value;
Then, application Da-Jin algorithm calculates the optimal segmenting threshold between pairwise independent peak value, the optimal segmenting threshold obtained is used to split Sublingual vegetation image effect figure, vegetation is split in top region, the Shadow segmentation of vegetation in body of the tongue is in the region of lowermost layer, realize being separated of vegetation and shade in the vegetation image effect figure of Sublingual, obtain the excrescent coarse segmentation image in Sublingual.
The concrete grammar that the method that the first iteration of the variable corrosion of described employing is corroded asks for candidate's sublingual vein area image is:
Sublingual vein image after setting binaryzation is bianry image I, does K erosion operation continuously to I, obtains bianry image I k:
I k=(...((IΘs 1)Θs 2)...Θs k),
In formula, Θ represents etching operation, and s represents corrosion unit;
Time corrosion of setting kth makes all connected regions in bianry image I all disappear, then the result of kth-1 corrosion is the center in the largest connected region of bianry image I, using the result of kth time iteration corrosion as seed points; In the bianry image I obtained according to this seed points, largest connected region is first venosomes, is removed by first venosomes from bianry image I; Repeat described process and obtain second venosomes, after first venosomes and second venosomes being arranged, obtain candidate's sublingual vein area image.
Described image extraction method provides data by image capture module: image capture module comprises camera control module, image capture module, image storage module and image database management module.
Camera control module is mainly for 2CCD video camera used in the present invention, and the connection completing video camera detects, start the function such as video camera and closedown video camera.
Image capture module, mainly comprises and starts to gather image and terminate to gather image function.Wherein, start to gather after image function enables, colour and each 6 width of near-infrared Sublingual image of current gathered person can be gathered respectively, and this 6 width image is temporarily stored in current operating environment, review 12 gathered width images by interface button.
Image storage module is activated by image capture module, after startup starts to gather image function, will eject the dialog box of input gathered person personal information, and system can be direct stored in correspondence database to collected sample automatic numbering.After information input, by the colour of this sample of continuous acquisition and near-infrared Sublingual image.After reaching the collection amount of images upper limit, by automatic spring personal information input dialogue frame, point out the image acquisition to next sample.
Image database management module mainly complete to this equipment gather image construction visible/near infrared Sublingual image library carry out the work such as information management and maintenance.This module can realize, by different keyword query, amendment gathered person information, checking whole colour and the near-infrared Sublingual image of arbitrary gathered person, and to attended operations such as the deletion of selected digital image and path amendments.
Sublingual image processing method:
The colour obtained for the visible ray in the present invention and near infrared light Sublingual image capturing system and near-infrared Sublingual image, sets forth the diagnostic characteristic that can quantize further that the sublingual vessel diagnostic method objectifies in research, as the contour extraction method of the features such as ventral surface of tongue, sublingual vein and Sublingual vegetation.
The extraction of ventral surface of tongue profile in the image of colored Sublingual:
First the interference in the region such as shade and tooth in oral cavity is removed: colored Sublingual image is formed primarily of regions such as ventral surface of tongue, lip, tooth, beard, skin of face and shades, bottom ventral surface of tongue and tongue, therefore, in the image of colored Sublingual, the extraction of tongue bottom profile is called ventral surface of tongue contours extract; Image Tooth and dash area due to distance tongue body close together, and have more marginal information, easily cause interference to the extraction in ventral surface of tongue region.Therefore for ensureing the accurate and efficient of segmentation, should first remove these interference regions.This patent takes the method based on color characteristic to remove these interference regions.Be Lab pattern by the color space of colored Sublingual image by RGB patten transformation, in Lab color space three different components, can find out that shade, tooth interference region and ventral surface of tongue region colourity difference in a component is larger, therefore a component in image extracted separately and histogram equalization process is carried out to it, strengthening the contrast in two regions further.After this process, the colourity between two regions has been provided with larger difference, and the interference region such as shade, tooth colourity is starkly lower than other regions.By thresholding process, pixel lower for chromatic value in a component is separated, obtain the pixel that a group is judged as interference region, again the rgb value of these pixel correspondence positions in the image of original color Sublingual is set to 0, the interference in the outlet intracavity major part region such as shade and tooth can be realized.
The coarse segmentation in ventral surface of tongue region: the Main Function of this step is by determining that one rough, the rectangular area be completely contained in wherein initializes GrabCut algorithm by ventral surface of tongue part, then, primary segmentation is carried out by GrabCut ventral surface of tongue region of getting it right.In the image of original color Sublingual, between ventral surface of tongue and lip, there is a shadow band, surround the region at ventral surface of tongue place, may be used for the initialization split.First adopt the method based on histogram contrast to obtain the Saliency maps of original color Sublingual image, in this Saliency maps, shadow band has the highest significance, can obviously and other regions distinguish and come.Through extracting and screening, can isolate shadow band in Saliency maps, obtain the minimum enclosed rectangle in this region simultaneously, this rectangle comprises ventral surface of tongue region completely.Adopt GrabCut algorithm to carry out GrabCut auto Segmentation to described ventral surface of tongue region again, can substantially be removed skin of face region and comprise the image in ventral surface of tongue region.But owing to there being some shadow regions near tongue body to remove between lip and ventral surface of tongue, in the image after segmentation, still likely comprise part lip-region.
Secondary splitting to ventral surface of tongue candidate region:
This step again adopts GrabCut algorithm to the ventral surface of tongue candidate region obtained above, realizes the secondary splitting to ventral surface of tongue region.First, the Saliency maps of gained ventral surface of tongue candidate image is above obtained based on histogram contrast.In this Saliency maps, the shadow region of not yet removing between lip and ventral surface of tongue has minimum significance.After removing low salient region by thresholding, obtain the minimum enclosed rectangle in the largest connected region in figure, and then apply this rectangular area initialization GrabCut algorithm, GrabCut auto Segmentation is carried out to the ventral surface of tongue candidate region after coarse segmentation, finally obtains ventral surface of tongue region more accurately.
Excrescent extracting method in the image of colored Sublingual:
Crossing of retroreflective regions detects: due to Sublingual vegetation, comparatively around body of the tongue region is more outstanding, causes the brightness of vegetation central area higher or easily form reflective spot.Thus, other highlight regions of ventral surface of tongue can cause very large interference to excrescent extraction.The salivary distribution that the highlight regions of ventral surface of tongue mainly covers due to tongue body periphery is uneven and formed under the irradiation of light, and subregion brightness is very high, and saturation is very low.To lose part sublingual vein color characteristic for cost, by the dual restriction to saturation and brightness, increase the weight of brightness value upper zone when carrying out retroreflective regions threshold value and choosing,
Concrete formula is as follows:
T s = &gamma; I max I max - I min S &OverBar; ,
Wherein, I maxand I minrepresent the maximum and minimum luminance value in ventral surface of tongue image respectively, for the saturation average in this region, γ is regulating parameter, T sfor the saturation threshold value obtained by the method.
After thresholding is carried out in the region that the ventral surface of tongue profile obtained in the extracting method of ventral surface of tongue profile in the image of colored Sublingual surrounds, the highlight regions affecting vegetation extraction is rejected completely, then use the image repair method based on Fast Marching to carry out area filling to disallowable region, obtain the image effect that Sublingual vegetation and other region vision differences of ventral surface of tongue obviously increase.
The excrescent coarse segmentation in Sublingual:
This step uses multi thresholds Da-Jin algorithm to find best trough between histogrammic adjacent peaks, vegetation is separated with body of the tongue, to realize the excrescent coarse segmentation in Sublingual.
First, make { 0,1,2 ... 255} represents Sublingual image 256 gray levels and adds up the grey level histogram of ventral surface of tongue image, check the minimum adjacent with maximum, when two, left and right minimum is all greater than given threshold value, think that this maximum is an independent peak, otherwise it is compared with a previous or rear maximum, gets large person as peak value;
Then, apply Da-Jin algorithm and calculate optimal segmenting threshold between par wise irrelevance peak value.Suppose that independently peak value is η 1, η 2, threshold value k is treated to C between adjacent independent peak 1and C 2two classes, according to σ 2inter-class variance formula determination cut-point, is shown below:
σ 2(k)=P 1(m 1-m G) 2+P 2(m 2-m G) 2
Wherein, m gfor the average gray of entire image, P 1k () is class C 1the probability occurred, P 2k () is class C 2the probability occurred, m 1, m 2c respectively 1and C 2the average gray of class.The k value that gradually changes makes σ 2inter-class variance value is maximum, and k is now the optimal segmenting threshold distinguishing these two classes.Use these cut-points to Image Segmentation Using, show that vegetation is divided in top region, shade is divided in the region of lowermost layer.
The vegetation candidate region, Sublingual that application the method coarse segmentation obtains remains excrescent complete area information, and vegetation region and surrounding body of the tongue background adhere to different layers separately.
Vegetation region, non-Sublingual based on provincial characteristics is rejected:
First, geometric measures is used to screen out non-vegetation region.Calculate the circularity of each connected region, rectangular degree and compression respectively.The region not meeting vegetation Morphological Features is rejected.
In view of excrescent protuberance can produce the feature of shade in its proximity, after above-mentioned process, vegetation and the shadow region around it lay respectively at the highest gray scale layer and minimum gray scale layer that multi thresholds Da-Jin algorithm delimit.Morphological dilations process is among a small circle carried out to region to be measured, if this expansion results does not overlap with shade, then non-vegetation region, this region is described, is rejected.
After above-mentioned process, the non-vegetation region in candidate's vegetation region that coarse segmentation obtains all is rejected, and is superimposed upon in the image of original color Sublingual at the edge in the vegetation region be retained and obtains final vegetation segmentation result.
The extraction of sublingual vein profile in the image of near-infrared Sublingual:
The extraction of ventral surface of tongue profile in the image of near-infrared Sublingual:
Because the collecting device that relates in the present invention to obtain two width images of same tongue body by same aperture, although two width images present different image effects due to the difference of imaging source, the tongue body state that both catch and all features are consistent.Therefore, the ventral surface of tongue profile in the image of near-infrared Sublingual can be determined simply by by ventral surface of tongue contour edge pixel position in the image of colored Sublingual.
Remove the reflective spot in near-infrared ventral surface of tongue image:
Caused by reflective spot in the image of near-infrared Sublingual is mainly reflective by the saliva of tongue body surface distributed inequality, if this reflective spot is on sublingual vein, the accuracy of sublingual vein segmentation will be affected.By the statistic histogram analysis to near-infrared ventral surface of tongue region, the gray-value variation scope of such reflective spot can be obtained, fluctuate near gray value 250.Can be rejected by simple thresholding method.
Then 8-neighborhood minimum method is used to fill the retroreflective regions detected, kept original image information as far as possible and the consistent image effect of vision, and gray scale morphology opening operation is carried out, globally to eliminate other highlight regions to the pixel that 8-neighborhood is reflective spot.
Extract in the process in candidate's sublingual vein region, morphologic filtering denoising is used further to the image after binaryzation, adopt the method for the first iteration corrosion of variable corrosion to ask for candidate's sublingual vein region.By the erosion operation of continuous several times, can in the hope of the utmost erode of bianry image.Utmost erode be each connected region by continuous corrosion until the union of the previous result that disappears completely.In order to obtain the utmost erode image of the binary image of sublingual vein image, can by doing continuous print etching operation to image, namely iteration corrosion realizes.
For a bianry image, if kth time corrosion makes all connected regions in image all disappear, then the result of kth-1 corrosion is exactly the center in largest connected region in original image.The result of last iteration being corroded is as seed points.According to the largest connected region that seed points obtains---namely after first venosomes, it is removed from former figure, repeat said process and can obtain second largest connected region, i.e. second venosomes.Because most Sublingual picture only presents two radicular veins, iteration corrosion only need be carried out twice.Small-sized noise in binary image, because Area comparison is little, naturally can be eliminated in the process of iteration corrosion.
Sublingual vein contours extract based on region-growing method: apply the seed points determined, by go reflective after ventral surface of tongue image based on, use region-growing method, when the difference of the gray value of the pixel of the pixel and current consideration that are in candidate region is less, then think that this pixel belongs to sublingual vein region.The enough hours growth processes of pixel increased when adjacent two secondary growths terminate, and the region now formed is the sublingual vein region finally split and obtain.
The sublingual vein contour edge obtained in near-infrared image is added in the image of colored Sublingual, the sublingual vein profile in the image of colored Sublingual can be obtained.Analyze the colouring information of this contour line institute enclosing region, more fully can describe and quantize sublingual vein color characteristic.

Claims (5)

1. visible ray and a near infrared light Sublingual image capturing system, is characterized in that, it comprises shell, light source module, camara module and display (4),
Shell is made up of left support plate (11), right support plate (12), upper backup pad (13), lower supporting plate (14), postnotum (16) and built-in inserted plate (15),
Left support plate (11), right support plate (12), upper backup pad (13), lower supporting plate (14) and postnotum (16) surround a cuboid cavity, in this cuboid cavity, light source module and camara module are set, the opening of cuboid cavity is as test lead, and this test lead is relative with postnotum (16) place end face; The inner surface of left support plate (11) and right support plate (12) arranges near the position of lower supporting plate (14) correspondence the groove be parallel to each other for a pair, and built-in inserted plate (15) grafting is fixed in groove; Display (4) is arranged on upper backup pad (13), and near postnotum (16) side;
Light source module comprises circuit board (21), near-infrared LED (22), electric filament lamp (23), four fans (24), fin (25) and Switching Power Supplies (26), circuit board (21) is fixedly installed on the opening of cuboid cavity, cuboid cavity is divided into the test space and image acquisition space, image acquisition space is the length space between circuit board (21) and postnotum (16); The center of circuit board (21) arranges image acquisition through hole, circuit board (21) on the surface in image acquisition space, fin (25) is set, the position at fin (25) four angles arranges a fan (24) respectively; The outer surface of circuit board (21) has near-infrared LED (22) along the circumferential uniform welding of image acquisition through hole, and the bezel locations all round of circuit board (21) outer surface arranges an electric filament lamp (23) respectively; Switching Power Supply (26) is arranged in image acquisition space, for providing working power for near-infrared LED (22), electric filament lamp (23), fan (24) and display (4);
Camara module comprises 2CCD industrial camera (31), near-infrared camera lenses (32), base (33) and switch (34), base (33) and switch (34) are arranged on the built-in inserted plate (15) in image acquisition space, 2CCD industrial camera (31) is fixed on base (33), 2CCD industrial camera (31) is rotary with near-infrared camera lenses (32), near-infrared camera lenses (32) stretches out image acquisition through hole, the photocentre of near-infrared camera lenses (32) and the center conllinear of circuit board (21) image acquisition through hole; 2CCD industrial camera (31) is via the network interface transmission data of switch (34);
Switching Power Supply (26) is also for providing working power for 2CCD industrial camera (31).
2. visible ray according to claim 1 and near infrared light Sublingual image capturing system, it is characterized in that, at the opening of cuboid cavity, the edge of upper backup pad (13) has a downward inclined plane, and the bottom center of this inclined plane has a nose outline curved support mouth.
3. visible ray according to claim 1 and near infrared light Sublingual image capturing system, is characterized in that, left support plate (11) and right support plate (12) arrange louvre respectively.
4. visible ray according to claim 1 and near infrared light Sublingual image capturing system, is characterized in that, circuit board (21) is aluminium base circuit board.
5. visible ray according to claim 1 and near infrared light Sublingual image capturing system, it is characterized in that, 2CCD industrial camera (31) has GigE and transmits network interface, and this GigE transmits network interface and is connected with the network interface of switch (34), and transmits data.
CN201510016921.1A 2015-01-13 2015-01-13 Visible light and near-infrared light sublingual image acquisition system Pending CN104510447A (en)

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