CN104491945A - Blood plasma collecting device - Google Patents
Blood plasma collecting device Download PDFInfo
- Publication number
- CN104491945A CN104491945A CN201410854903.6A CN201410854903A CN104491945A CN 104491945 A CN104491945 A CN 104491945A CN 201410854903 A CN201410854903 A CN 201410854903A CN 104491945 A CN104491945 A CN 104491945A
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- China
- Prior art keywords
- blood
- connector
- anticoagulant
- air probe
- air
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/38—Removing constituents from donor blood and storing or returning remainder to body, e.g. for transfusion
Abstract
The invention discloses a blood plasma collecting device. The blood plasma collecting device comprises a needle for collecting blood, a first connector, a first puncture device for charging an anticoagulant, a first anticoagulant tube connected with the first puncture device, a blood filter, a blood tube connected with the blood filter, a centrifuging cup for separating the blood plasma, a second connector, a blood plasma collecting bag, a second puncture device for charging normal saline, an anticoagulant pump, a blood pump, a first air probe, a second air probe, a third air probe and a fourth air probe, wherein the probes are used for detecting air; the first air probe and the second air probe are sequentially arranged on the blood tube between the first connector and the blood filter along the blood extracting direction; the third air probe is arranged on the anticoagulant tube between the anticoagulant pump and the first connector; the fourth air probe is arranged on the blood tube between the blood filter and the blood pump. With the adoption of the blood plasma collecting device, red blood cells in an outlet of the centrifuging cup and the air and pressure in the tube can be detected during collecting and returning.
Description
Technical field
The invention belongs to technical field of medical equipment, be specifically related to a kind of sampled plasma device.
Background technology
Adopt slurry, full name is Plasma Pheresis/Apheresis Plasma, refers to human whole blood to go out blood plasma through physical method for separation, and all the other components is also passed to a process in plasma donor body.
Blood-collecting station sets up through examination & approval, gathers the unit of supply blood products production raw blood plasma.Nearly ten years, along with the progressively increase of China's blood products volume of production, various places are provided with a large amount of blood-collecting station in succession, to ensure blood products production raw material.
Meet and offer the personnel that slurry requires and can become and offer slurry personnel after medical fitness.In order to ensure the health offering slurry personnel, national correlation department specifies: everyone gathers plasma volume at every turn must not more than 580ml (containing anticoagulant solution, be converted into quality with volume and be no more than 600g); Adopt slurry interval and must not be shorter than 14 days.
Sampled plasma device has been widely used in blood-collecting station, Blood Center or medical usage at present, the effect of sampled plasma device is exactly be separated by blood constituent according to the difference of blood constituent density, obtain high-quality blood plasma, and guarantee that other compositions of blood are injury-free, feed back to safely in plasma donor body.If the blood plasma gathered has been mixed into erythrocyte, the quality of blood plasma can be affected, air is forbidden to enter blood when feeding back erythrocyte, prevent angiostenosis place from forming air embolism, hinder blood circulation path, cause shock, and in the process gathered and feed back, if blood pump rotating speed is too fast, the negative pressure produce human body and the too high meeting of malleation cause the discomfort of plasma donor.
Summary of the invention
The object of the invention is to solve the problem, a kind of sampled plasma device that can detect air in collection and returning step in the erythrocyte in Centrifuge Cup exit, pipeline and pressure is provided.
For solving the problems of the technologies described above, technical scheme of the present invention is: a kind of sampled plasma device, comprises for the syringe needle of blood collection, connector one, first perforator, the anticoagulant pipeline be connected with the first perforator, blood filter, the transducer potector be connected with blood filter, Centrifuge Cup for separating of blood plasma, connector two, blood plasma collecting bag, the second perforator, anticoagulant pump, blood pump and air probe one, air probe two, air probe three and air probe four for detecting air; Described syringe needle, anticoagulant pipeline, blood filter are connected with connector one respectively, and described blood filter is connected with the import of Centrifuge Cup by transducer potector; Described connector two is connected with the second perforator with the outlet of Centrifuge Cup, blood plasma collecting bag respectively; Described anticoagulant pipeline is arranged on anticoagulant pump, and the transducer potector between blood filter and Centrifuge Cup is arranged on blood pump; Transducer potector between described connector one and blood filter is provided with air probe one and air probe two successively along the direction extracting blood; Anticoagulant pipeline between anticoagulant pump and connector one is provided with air probe three; Transducer potector between blood filter and blood pump is provided with air probe four.
Preferably, the erythrocyte detector be located between connector two and Centrifuge Cup on transducer potector is also comprised.
Preferably, the pressure detector be connected with blood filter is also comprised.
Preferably, also comprise the valve one be located between blood filter and air probe four on transducer potector, be located at the valve two between connector two and blood plasma collecting bag, and be located at the valve three between connector two and the second perforator.
Preferably, the electronic scale for weighing blood plasma collecting bag quality is also comprised.
Preferably, also comprise position limiting clamp, anticoagulant pipeline and transducer potector are installed on position limiting clamp.
Preferably, described connector one and connector two are three way cock.
Preferably, described first perforator is connected for accessing anticoagulant with anticoagulant bag, and the second perforator is connected for accessing normal saline with normal saline bottle.
The invention has the beneficial effects as follows: sampled plasma device provided by the present invention, ducted air in collection and returning step can be detected by the several air probe be arranged on pipeline, prevent air intravasation from causing damage to human body; Detect erythrocyte by the erythrocyte detector be arranged between Centrifuge Cup and connector two, preventing erythrocyte from entering blood plasma collecting bag affects acquisition quality; Detect by the pressure detector be connected with blood filter the pressure gathered and in returning step, prevent the discomfort that hypertonia causes human body.
Accompanying drawing explanation
Fig. 1 is the structural representation of sampled plasma device of the present invention.
Description of reference numerals: 1, syringe needle; 2, connector one; 3, the first perforator; 4, anticoagulant pipeline; 5, blood filter; 6, transducer potector; 7, Centrifuge Cup; 8, connector two; 9, blood plasma collecting bag; 10, the second perforator; 11, anticoagulant pump; 12, blood pump; 13, air probe one; 14, air probe two; 15, air probe three; 16, valve one; 17, air probe four; 18, erythrocyte detector; 19, valve two; 20, valve three; 21, position limiting clamp; 22, pressure detector; 23, electronic scale.
Detailed description of the invention
Below in conjunction with the drawings and specific embodiments, the present invention is described further:
As shown in Figure 1, sampled plasma device of the present invention, comprise for the syringe needle 1 of blood collection, connector one 2, first perforator 3, the anticoagulant pipeline 4 be connected with the first perforator 3, for filtering microgranule and the blood filter 5 of azelon in consumptive material, the transducer potector 6 be connected with blood filter 5, Centrifuge Cup 7 for separating of blood plasma, connector 28, blood plasma collecting bag 9, second perforator 10, anticoagulant pump 11, blood pump 12 and air probe 1, air probe 2 14, air probe 3 15 and air probe 4 17 for detecting air; First perforator 3 is connected for accessing anticoagulant with anticoagulant bag, and the second perforator 10 is connected for accessing normal saline with normal saline bottle.
Connector 1 and connector 28 are three way cock, and syringe needle 1, anticoagulant pipeline 4, blood filter 5 are connected with connector 1 respectively, and blood filter 5 is connected with the import of Centrifuge Cup 7 by transducer potector 6; Connector 28 is connected with the second perforator 10 with the outlet of Centrifuge Cup 7, blood plasma collecting bag 9 respectively; Blood plasma collecting bag 9 is slightly stable to be suspended on electronic scale 23 support arm, electronic scale 23 can weigh blood plasma collecting bag 9 quality in real time, during collection, electronic scale detects that quality (comprising blood plasma collecting bag 9 quality) is more than 680g, machine warning " electronic scale quality is excessive ".
Anticoagulant pipeline 4 and transducer potector 6 are transparent hose, and anticoagulant pipeline 4 is arranged on anticoagulant pump 11, and the transducer potector 6 between blood filter 5 and Centrifuge Cup 7 is arranged on blood pump 12; By the running of blood pump 12, whole blood is sent into Centrifuge Cup 7, maybe get back to human body by defeated for the erythrocyte after separation; In order to make pipeline and pump coordinate better, the both sides of anticoagulant pump 11 and blood pump 12 are equipped with position limiting clamp 21, and anticoagulant pipeline 4 and transducer potector 6 are arranged on position limiting clamp 21 and locate.
Air probe is responsible for the air in signal piping in machine runs, vital effect is played to Blood donation safety, its operation principle is: air probe is according to ultrasonic wave principle, utilizes the difference of ultrasound wave transmission speed in liquids and gases to identify gas and liquid.
Transducer potector 6 between connector 1 and blood filter 5 is provided with air probe 1 and air probe 2 14 successively along the direction extracting blood; Transducer potector 6 between blood filter 5 and blood pump 12 is provided with air probe 4 17; Traditional slurry of adopting is divided into three circulations, when first time and second time feed back time, stops feeding back when air probe 4 17 detects air; When last feedback time, air probe 1 and air probe 2 14 any one stop feeding back when air being detected; During each circle collection, after after air probe 4 17 detects liquid, blood pump 12 starts to count up to 330 circles, electronic scale does not detect the increase of plasma purity, and machine can be warned " crossing long-time non-pulp ".
Anticoagulant pipeline 4 between anticoagulant pump 11 and connector 1 is provided with air probe 3 15; In gatherer process, send air alarm signal when air probe 3 15 finds air, prompting operator anticoagulant is finished or anticoagulant pipeline is provided with problem.
Enter blood plasma collecting bag to prevent erythrocyte and affect acquisition quality, between connector 28 and Centrifuge Cup 7, transducer potector 6 is provided with erythrocyte detector 18, erythrocyte detector 18 is the critical components ensureing to adopt slurry quality, be a kind of photoelectric sensor, it carrys out detection zone according to the difference of light propagation characteristic in different colours liquid and divides erythrocyte and blood plasma.
In order to the discomfort preventing hypertonia from causing human body, blood filter 5 is connected with pressure detector 22, pressure detector 22 ensures the vitals offering slurry safety, pressure detector 22 is for detecting the pressure in collection and returning step, when sending warning higher than machine during setting value, operator can reduce pressure by the rotating speed adjusting blood pump 12.
Between blood filter 5 and air probe 4 17, transducer potector 6 is provided with valve 1, valve 2 19 is provided with between connector 28 and blood plasma collecting bag 9, valve 3 20 is provided with between connector 28 and the second perforator 10, when gathering blood plasma, open valve 1 and valve 2 19, valve-off 3 20, makes whole blood flow into Centrifuge Cup 7 by blood pump 12, and separated blood plasma flows into blood plasma collecting bag 9 by the valve 2 19 opened; When feeding back erythrocytic, to needing the user of supplementing water to add a valve 3 20, valve-off 2 19, the normal saline opening valve 1 and the access of valve 3 20, second perforator 10 feeds back to human body.
The work process of above-mentioned sampled plasma device is:
Open sampled plasma device, syringe needle 1 is inserted human body, by the operation of anticoagulant pump 11 and blood pump 12, the whole blood feeding Centrifuge Cup 7 of mixing anticoagulant is carried out centrifugal.Along with Centrifuge Cup 7 speed increases, whole blood is by progressively layering, and the cell that density is larger is split into skin.Can export from Centrifuge Cup 7 overflow when the whole blood through being separated is full of blood plasma after Centrifuge Cup 7, enter after the detection of erythrocyte detector 18 in blood plasma collecting bag 9, by electronic scale 23 detect overflow blood plasma number; After the blood plasma detected in blood plasma collecting bag 9 when electronic scale 23 reaches preset value, stop the operation of anticoagulant pump 11, blood pump 12 and Centrifuge Cup 7, terminate this circle collection task.Start to feed back erythrocyte after Centrifuge Cup 7 stops operating, the erythrocyte in Centrifuge Cup 7 etc. is fed back the Huis' body by blood pump 12 antikinesis.Liquid case in returning step in the continuous signal piping of air probe, warns once find that air will send and stops feeding back.After feeding back, start the collecting work of next circulation, so circulate.
Those of ordinary skill in the art will appreciate that, embodiment described here is to help reader understanding's principle of the present invention, should be understood to that protection scope of the present invention is not limited to so special statement and embodiment.Those of ordinary skill in the art can make various other various concrete distortion and combination of not departing from essence of the present invention according to these technology enlightenment disclosed by the invention, and these distortion and combination are still in protection scope of the present invention.
Claims (8)
1. a sampled plasma device, it is characterized in that: comprise the syringe needle (1) for blood collection, connector one (2), first perforator (3), the anticoagulant pipeline (4) be connected with the first perforator (3), blood filter (5), the transducer potector (6) be connected with blood filter (5), for separating of the Centrifuge Cup (7) of blood plasma, connector two (8), blood plasma collecting bag (9), second perforator (10), anticoagulant pump (11), blood pump (12) and the air probe one (13) for detecting air, air probe two (14), air probe three (15) and air probe four (17),
Described syringe needle (1), anticoagulant pipeline (4), blood filter (5) are connected with connector one (2) respectively, and described blood filter (5) is connected by the import of transducer potector (6) with Centrifuge Cup (7); Described connector two (8) is connected with the second perforator (10) with the outlet of Centrifuge Cup (7), blood plasma collecting bag (9) respectively;
Described anticoagulant pipeline (4) is arranged on anticoagulant pump (11), and the transducer potector (6) between blood filter (5) and Centrifuge Cup (7) is arranged on blood pump (12);
Transducer potector (6) between described connector one (2) and blood filter (5) is provided with air probe one (13) and air probe two (14) successively along the direction extracting blood; Anticoagulant pipeline (4) between anticoagulant pump (11) and connector one (2) is provided with air probe three (15); Transducer potector (6) between blood filter (5) and blood pump (12) is provided with air probe four (17).
2. sampled plasma device according to claim 1, is characterized in that: also comprise the erythrocyte detector (18) be located between connector two (8) and Centrifuge Cup (7) on transducer potector (6).
3. sampled plasma device according to claim 1, is characterized in that: also comprise the pressure detector (22) be connected with blood filter (5).
4. according to the arbitrary described sampled plasma device of claims 1 to 3, it is characterized in that: also comprise the valve one (16) be located between blood filter (5) and air probe four (17) on transducer potector (6), be located at the valve two (19) between connector two (8) and blood plasma collecting bag (9), and be located at the valve three (20) between connector two (8) and the second perforator (10).
5., according to the arbitrary described sampled plasma device of claims 1 to 3, it is characterized in that: also comprise the electronic scale (23) for weighing blood plasma collecting bag (9) quality.
6., according to the arbitrary described sampled plasma device of claims 1 to 3, it is characterized in that: also comprise position limiting clamp (21), anticoagulant pipeline (4) and transducer potector (6) are installed on position limiting clamp (21).
7., according to the arbitrary described sampled plasma device of claims 1 to 3, it is characterized in that: described connector one (2) and connector two (8) are three way cock.
8. according to the arbitrary described sampled plasma device of claims 1 to 3, it is characterized in that: described first perforator (3) is connected for accessing anticoagulant with anticoagulant bag, and the second perforator (10) is connected for accessing normal saline with normal saline bottle.
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CN201410854903.6A CN104491945B (en) | 2014-12-31 | 2014-12-31 | A kind of sampled plasma device |
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CN201410854903.6A CN104491945B (en) | 2014-12-31 | 2014-12-31 | A kind of sampled plasma device |
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CN104491945B CN104491945B (en) | 2017-06-06 |
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Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
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CN105498010A (en) * | 2016-01-13 | 2016-04-20 | 重庆三大伟业制药有限公司 | Full-automatic whole blood collection and separation device and method |
CN105950457A (en) * | 2016-03-15 | 2016-09-21 | 绍兴市人民医院 | Apparatus for enriching stem cells |
CN106913918A (en) * | 2017-03-29 | 2017-07-04 | 艾沃生物科技(苏州)有限公司 | A kind of external circulating therapy centrifugal plasma isolation of purified instrument |
CN107790298A (en) * | 2016-08-29 | 2018-03-13 | 赛若麦得(上海)生物技术有限公司 | A kind of sampled plasma device and its control method |
CN110859635A (en) * | 2019-10-18 | 2020-03-06 | 四川南格尔生物科技有限公司 | Plasma sampling pipeline system and sampling method |
CN116392857A (en) * | 2023-06-08 | 2023-07-07 | 深圳赛桥生物创新技术有限公司 | Sample collection method and device |
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CN204170180U (en) * | 2014-10-14 | 2015-02-25 | 四川南格尔生物科技有限公司 | A kind of single use removes blood fat separator |
CN204352269U (en) * | 2014-12-31 | 2015-05-27 | 成都市佳颖医用制品有限公司 | A kind of sampled plasma device |
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Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105498010A (en) * | 2016-01-13 | 2016-04-20 | 重庆三大伟业制药有限公司 | Full-automatic whole blood collection and separation device and method |
CN105498010B (en) * | 2016-01-13 | 2019-01-11 | 重庆三大伟业制药有限公司 | Full-automatic whole blood collecting and separating device and method |
CN105950457A (en) * | 2016-03-15 | 2016-09-21 | 绍兴市人民医院 | Apparatus for enriching stem cells |
CN107790298A (en) * | 2016-08-29 | 2018-03-13 | 赛若麦得(上海)生物技术有限公司 | A kind of sampled plasma device and its control method |
CN106913918A (en) * | 2017-03-29 | 2017-07-04 | 艾沃生物科技(苏州)有限公司 | A kind of external circulating therapy centrifugal plasma isolation of purified instrument |
CN110859635A (en) * | 2019-10-18 | 2020-03-06 | 四川南格尔生物科技有限公司 | Plasma sampling pipeline system and sampling method |
CN116392857A (en) * | 2023-06-08 | 2023-07-07 | 深圳赛桥生物创新技术有限公司 | Sample collection method and device |
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Address after: 610100 No. 138 Wuxing Street, Damian Street, Longquanyi District, Chengdu City, Sichuan Province Patentee after: CHENGDU JIAYING MEDICAL PRODUCT CO., LTD. Address before: 610100 Wuxing Street, Damian Street, Longquanyi District, Chengdu City, Sichuan Province Patentee before: CHENGDU JIAYING MEDICAL PRODUCT CO., LTD. |
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