CN104491830A - Traditional Chinese medicine composition for preventing and controlling tuberculosis and preparation method thereof - Google Patents

Traditional Chinese medicine composition for preventing and controlling tuberculosis and preparation method thereof Download PDF

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CN104491830A
CN104491830A CN201510033410.0A CN201510033410A CN104491830A CN 104491830 A CN104491830 A CN 104491830A CN 201510033410 A CN201510033410 A CN 201510033410A CN 104491830 A CN104491830 A CN 104491830A
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张金梅
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Abstract

The invention discloses a traditional Chinese medicine composition for preventing and controlling tuberculosis. The traditional Chinese medicine composition is composed of tortoise plastron, donkey-hide gelatin, cordyceps sinensis, lily, dried rehmannia root, unibract fritillary bulb, curcuma aromatica, tangerine pith, loofah, Chinese thorowax root, lotus stamen, lalang grass rhizome, dried tangerine or orange peel, radix paeoniae alba, figwort root, panax notoginseng, Gorgon euryale seed, sessile stemona root, radix asteris, radix glehniae, ginger, licorice roots northwest origin and Chinese date according to certain weight ratios. The traditional Chinese medicine composition has the effects of nourishing yin and suppressing yang, tonifying the kidney and strengthening bone, moisturizing dryness by nourishing yin, and removing heat to cool blood, and can effectively preventing and controlling tuberculosis.

Description

A kind of control Chinese medicine composition lungy and preparation method thereof
Technical field
The present invention relates to a kind of Chinese medicine composition, be specifically related to a kind of control Chinese medicine composition lungy.The invention still further relates to the preparation method of this Chinese medicine composition.
Background technology
Tuberculosis is a kind of chronic infectious disease of serious harm people ' s health, and by mycobacteria, (mainly mycobacterium tuberculosis (Mycobacterium tuberculosis), causes also known as " tubercule bacillus " (tubercle bacillus).Tuberculosis usually infects and destroys lung and (claims " pulmonary tuberculosis ", also known as " pulmonary tuberculosis " or be called " spitting of blood sick ") and lymphsystem (claim " Tuberculous lymphadenopathy ", also known as " lymphoid tuberculosis "), but other organ as brain, central nervous system, blood circulation, urinary system, skeleton, joint, even skin also can infected (as infect brain can cause " tuberculous meningitis ").China's tuberculosis number of patients occupies second place of the world, is only second to India.Tuberculosis is one of major disease of China's priority control.Tuberculosis is the highest with juvenile onset rate, and according to statistics, the whole world about has 1,700,000,000 people to infect tuberculosis, every year dead 3,000,000 people, and therefore tuberculosis becomes " the second cancer " by a lot of people.Tubercule bacillus passes through respiratory tract infection, attack pulmonary at first, when Abwehrkraft des Koepers reduction to be easy to cause the inflammatory infiltration sexually transmitted disease (STD) of lungs to become, clinical manifestation weight lungy differs, and common are local and the General Symptomies such as cough, expectoration, hemoptysis, chest pain, heating, weak, loss of appetite.All multiple organ of health are got involved and can be caused tuberculosis, the most common with pulmonary tuberculosis clinically, as tuberculous pleuritis, tuberculous meningitis, Tuberculous tuberculosis of intestine, renal tuberculosis, lymphoid tuberculosis, pelvic tuberculosis etc., tuberculosis is quite a few sees for other, is generally secondary to pulmonary tuberculosis more.
Current modern medicine is used for the treatment of lungy mainly based on Western medicine, and as rifampicin, streptomycin etc., these medicines not only have many side effect, as auditory dysesthesia, and tinnitus is dizzy, visual deterioration, hematuria, oliguria etc., and along with long-term and irrational use, the drug resistance of tulase also can be more and more higher, the traditional Chinese medical science is said, prevention of diseae, therefore preventing exacerbation after being taken ill is also very important in control lungy.
Summary of the invention
The object of this invention is to provide a kind of Chinese medicine composition, this Chinese medicine composition has control for treatment tuberculosis and takes into account, and determined curative effect is easy to use, the feature had no side effect.
Another object of the present invention is to provide the preparation method of this control Chinese medicine composition lungy.
Inventor is in clinical treatment practice for many years, observe the misery that tuberculosis is brought to patient, according to the law of development of this disease, and the combination principle of Chinese medicine, and by a large amount of clinical verifications, Exploration and conclusion goes out a kind of new formula preventing and treating Chinese medicine composition lungy repeatedly, the present invention selects Carapax et Plastrum Testudinis, Colla Corii Asini, Cordyceps, Bulbus Lilii, Radix Rehmanniae, Bulbus Fritillariae Cirrhosae, Radix Curcumae, Vascular aurantii, Retinervus Luffae Fructus, Radix Bupleuri, Stamen Nelumbinis, Rhizoma Imperatae, Pericarpium Citri Reticulatae, the Radix Paeoniae Alba, Radix Scrophulariae, Radix Notoginseng, Semen Euryales, the Radix Stemonae, Radix Asteris, Radix Glehniae, Rhizoma Zingiberis Recens, Radix Glycyrrhizae, Fructus Jujubae combines, each efficacy of drugs is made by these drug regimens to produce synergism, make it that there is nourishing YIN for suppressing the hyperactive YANG, invigorating function of kidney and strengthening bone, nourishing YIN and moistening the lung, effect of clearing away heat and cooling blood, thus effectively can prevent and treat tuberculosis.
The effect of Chinese medicine of the present invention:
Wherein:
Carapax et Plastrum Testudinis: be sternite and the carapace of Testudinidae animal chinemys reevesii.Nature and flavor: salty, sweet, be slightly cold.Return liver, kidney, heart channel.Effect: nourishing YIN for suppressing the hyperactive YANG, kidney tonifying bone strengthening, Gu through only collapsing, reinforcing the heart of nourishing blood.Carapax et Plastrum Testudinis contains several amino acids, protein, fat and calcium salt etc. containing bone gelatin, hydrolysate.Cure mainly hyperactivity of YANG due to deficiency of YIN, yin asthenia generating intrinsic heat, stirring-up of pathogenic wind in the interior resulting from deficiency.To suffer from a deficiency of the kidney the atrophic debility of bones, infantile metopism.Deficiency of YIN-blood, palpitation with fear, insomnia, forgetful.This product energy tonifying kidney-yin is appointed with Gu Chong, again heat clearing away cold in nature, and holding concurrently can cooling blood for hemostasis.For the menorrhagia of YinXuXueRe, metrorrhagia and metrostaxis.This product can nourish blood reinforcing the heart, can be used for insomnia forgetfulness.
Colla Corii Asini: for the skin of equine species donkey Equus Asinus L. is through decocting, concentrating the solid gum made.Nature and flavor: sweet are flat.Return lung, liver, kidney channel.Effect: YIN nourishing of enriching blood, moisturizes, hemostasis.For blood deficiency and yellow complexion, dizzy cardiopalmus, flesh flaccidity is unable, dysphoria and insomnia, stirring-up of pathogenic wind in the interior resulting from deficiency, xeropulmonary cough, and chronic cough is spat blood, haematemesis hematuria, metrorrhagia of having blood in stool, vaginal bleeding during pregnancy." detailed outline ": Colla Corii Asini, will just enrich blood and liquid greatly, therefore can lung heat clearing tonifying YIN and control all cards.By Chen Ziming cloud: tonify deficiency animal glue, remove wind Colla Corii Asini.Cheng Wuji cloud: deficiency of YIN person, tonifying with drugs of thick flavor, Colla Corii Asini sweet, with nourishing YIN blood.Yang Shiying cloud: all control to breathe heavily cough, no matter the deficiency of the lung, excess of the lung, can under can temperature, palpus Colla Corii Asini is to pacify lung lung moistening, and its property is peaceful, is lung meridian key medicine.
Cordyceps: for section ergot fungus cordyceps sinensis bacterium Cordyceps sinensis (Berk.) Sacc. colonizes in Stroma on Hepialidae insect larvae and larva cadaveric complex.Nature and flavor: sweet are flat.Return lung, kidney channel.Effect: invigorating the lung and the kidney, hemostasis and phlegm.For chronic cough dyspnea due to deficiency, chronic cough is spat blood, impotence and seminal emission, soreness of waist and knee joint." Chongqing hall random notes ": Cordyceps, the property of the flat benefit of tool gentleness is the panacea of intermittent fever of deficiency type, stuffy sensation of deftciency type, deficiency-distension, empty pain, merit victory Aspongopus.All hyperactivity of YANG due to deficiency of YIN and be dyspnea phlegmatic cough person, throwing know effect, not only have specially can be also for regulating menstruation seed.Mr.'s Zhou Zhigui cloud, must be good with day in the Autumnal Equinox person of adopting.Male meaning summer taker can control the sagging disease of yang-energy.
Bulbus Lilii: be the dry meat scale leaf of liliaceous plant tiger lily Lilium lancifolium Thunb., Bulbus Lilii Lilium brownii F.E.Brown var. viridulum Baker or Lilium tenuifolium Lilium pumilum DC..Nature and flavor: sweet, cold.GUIXIN, lung meridian.Effect: nourishing YIN and moistening the lung, clearing away heart-fire for tranquillization.For deficiency of YIN chronic cough, sputum mixed with blood, fidgets due to deficiency is palpitated with fear, insomnia and dreamful sleep, absentminded." Bencao Jingshu ": Bulbus Lilii, main pathogen abdominal distention.So-called pathogen person, namely pathogenic heat also.Pathogenic heat are in abdomen event abdominal distention, and its pathogenic heat are then swollen clearly disappears.Separate the pathogenic heat of sharp heart man, then pained from Liao.Kidney controlling urination and defecation, kidney and large intestine two are through having pathogenic heat then not tonneau, the pathogenic heat of clear two warps, then defecation diarrhea.The invigorating middle warmer of sweet energy, the clear then gas of heat is raw, therefore invigorating the spleen and replenishing QI.Heat clearing away diuresis, thus except edema, set out swollen.Feeling of fullness cold and heat, the whole body pain, breast is difficult, and sufficient Yang Mingre is also; Sore throat person, hands few sun three Jiao, hands few cloudy heart man heat are also; Tears, tear, lung liver-heat is also; Clear sun bright three is felt terribly worried the heat in portion, then all diseases of coming up are from removing.
Radix Rehmanniae: be the fresh or dried root of scrophulariaceae rehmannia glutinosa plant Rehmannia glutinosa Libosch..Nature and flavor: sweet, cold.GUIXIN, liver, kidney channel.Effect: clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting.Can be used for Tianjin wound thirsty, interior-heat is quenched one's thirst.This product is sweet cold, can among heat clearing away YIN nourishing and the production of body fluid promoting, cold in nature and enter blood system, can not only the heat of clearing heat in YING system blood system and removing heat from blood, and sweet in the mouth is cold in nature can promote the production of body fluid, and has the effect of nourishing YIN and clearing away heat.Research shows: the existing anastalsis of Radix Rehmanniae, has blood coagulation resisting function again, and the yellow needles of Radix Rehmanniae ethanol extraction gained can shorten rabbit clotting time.
Bulbus Fritillariae Cirrhosae: be the dry bulb of liliaceous plant Bulbus Fritillariae Cirrhosae Fritillaria cirrhosa D.Don, Fritillaria unibracteata Fritillaria unibracteata Hsiao et K.C.Hsia, Gansu Bulbus Fritillariae Uninbracteatae Fritillaria przewalskii Maxim. or Bulbus Fritillariae cirrhosae Fritillaria delav ayi Franch..Nature and flavor: bitter, sweet, are slightly cold.Return lung, heart channel.Effect: clearing heat and moistening lung, preventing phlegm from forming and stopping coughing.For lung-heat type cough, the few expectorant of dry cough, deficiency of YIN chronic cough, sputum with blood." book on Chinese herbal medicine is not mentionleted alone ": the gas Bulbus Fritillariae Uninbracteatae of breast pent-up of relieving boredom, controls the unhappy how melancholy person of gas in the heart very meritorious.Wang Haogu: Bulbus Fritillariae Uninbracteatae, be lung meridian edema caused by disorder of QI medicine also, Zhong Jing controls blocked-up chest due to accumulation of coldphlegm, outer without heat syndrome person, three things little sunken chest soup master it, white loose also can, there to be Bulbus Fritillariae Uninbracteatae also in it.Cheng Wuji cloud: pungent loose and hardship is let out, the toil of Radix Platycodonis, Bulbus Fritillariae Uninbracteatae, in order to the therapeutic method to keep the adverse QI flowing downwards.
Radix Curcumae: be the dried root of zingiberaceous plant RADIX CURCUMAE Curcuma wenyujin Y. H. Chen et C. Ling, Rhizoma Curcumae Longae Curcuma longa L., Guangxi zedoary Curcuma kwangsiensis S. G. Lee et C. F. Liang or Rhizoma Curcumae Curcuma phaeocaulis Val..Nature and flavor: pungent, bitter, cold.Return liver, the heart, lung meridian.Effect: regulating qi to disperse stagnation, heart fire-clearing upset-relieving, promoting the function of the gallbladder to alleviate jaundice, removing heat from blood removing blood stasis with potent drugs.Cure mainly: all pains of breast abdomen side of body rib, lose the heart demented, calentura coma, spit blood, epistaxis, hematuria, stranguria with blood, women's vicarious menstruation, jaundice.The pungent loose hardship of this product is let out, heat clearing away cold in nature, can have one's ideas straightened out by heart fire-clearing upset-relieving.Radix Curcumae pungent drugs can disperse and bitter drugs can descend, fragrance a surname reach, cold in nature again can heat clearing away.Both entered edema caused by disorder of QI with promoting QI circulation for relieving depression, entered again blood system with cooling blood and dissolving stasis, and be the gas medicine in blood, be used for the treatment of the chest pain of QI and blood stasis.
Vascular aurantii: be the grain in the peel of rutaceae orange Citrus reticulata Blanco.Nature and flavor: bitter are flat.Return liver, spleen two warp.Effect: dredging collateral; Regulate the flow of vital energy; Reduce phlegm.Main blockage of meridian-QI; Chronic cough chest pain; Sputum mixed with blood; Get sick from drinking too much wine thirsty.
Retinervus Luffae Fructus: be the vascular bundle of the dry mature fruit of cucurbitaceous plant Fructus Luffae Luffa cylindrica (L.) Roem..Nature and flavor: sweet are flat.Return lung, stomach, Liver Channel.Effect: dredging collateral, invigorates blood circulation, and dispels the wind.For arthralgia pain contracture, distending pain in the chest and hypochondrium, galactostasis." book on Chinese herbal medicine is new again ": the meridian dredging, and blood vessels, reduces phlegm pleasant.
Radix Bupleuri: be Umbelliferae herbaceos perennial Radix Bupleuri Bupleurum chinense DC.(Radix Bupleuri) or Radix Bupeuri Scorzonerfolii. Bupleurum scorzonerifolium Willd.(Radix Bupleuri Scorzonerifolii) root or herb.Nature and flavor: bitter, pungent, be slightly cold.Return liver, gallbladder meridian.Effect: reducing fever by reconciliation, dispersing the stagnated live-QI to relieve the stagnation of QI, ascending up spleen-Qi and Yang.Modern pharmacological research proves: " medicineization justice ": Radix Bupleuri, and property is gently clear, and main liter falls apart, mildly bitter flavor, main soothing the liver." book on Chinese herbal medicine is through separating ": Radix Bupleuri, stagnation of QI person in its main trusted subordinate's the intestines and stomach, trusted subordinate's the intestines and stomach, five hide six mansions also, and Zang Fu is totally ten two warps, gallbladder is all depended in all 11 Tibetan, and Radix Bupleuri is gently clear, and rise and reach courage, courage bar reaches, then 11 hide from Xuanhua, therefore in trusted subordinate's the intestines and stomach, all have stagnation of QI, all can fall apart also.Its main diet accumulator, lid diet enters stomach, the spleen transporting essential substances to the liver, the evacuation of liver, borrow again few positive gallbladder be the master of hair growth promoting also, Radix Bupleuri liter reaches courage, then liver can fall apart essence, and diet gathers from lower.Shaoyang channel row half exterior and half interior, few sun, by evil, evilly also then to be trembled with fear in the moon, evil and in Yang Zere, Radix Bupleuri treating SHAO YANG disease by mediation, therefore the pathogen of main cold and heat also.
Stamen Nelumbinis: be the dry stamen of nymphaeaceae plant lotus Nelumbo nucifera Gaertn..Nature and flavor: sweet, puckery are flat.GUIXIN, kidney channel.Effect: reinforcing the kindey to control nocturnal emission.For emission and spermatorrhea, leukorrhagia, frequent micturition." book on Chinese herbal medicine is looked for the truth ": Stamen Nelumbinis, Gan Wen and puckery, merit and Semen Nelumbinis slightly with.But adstringency is in the majority, do not tremble with fear puckery like Os Draconis, have receipts the moon, determine the wonderful of soul peace soul; Concha Ostreae is salty and bitter to be slightly cold, the merit that having concurrently is hard antipyretic; The power that Fructus Rosae Laevigatae has on foot resistance puckery, and without the reason ear of the logical kidney that clears away heart-fire.
Rhizoma Imperatae: be the rhizome of grass perennial herb Herba Imperatae Imperata cylindrica.Nature and flavor: sweet, cold.Return lung, stomach, urinary bladder channel.Effect: cooling blood for hemostasis, clearing away heat and promoting diuresis.Spit blood for heat in blood, epistaxis, hematuria, calentura excessive thirst, jaundice, edema, the puckery pain of pyretic stranguria; Acute nephritis edema." Bencao Jingshu " is recorded: impairment caused by overstrain void is won, must interior-heat, and Rhizoma Imperatae is sweet can spleen reinforcing, sweet, though cold and do not violate stomach.Gan Hanneng is except interior-heat, therefore main impairment caused by overstrain void is won.Strengthening the spleen so invigorating middle warmer, heat extraction so QI invigorating, the beneficial blood of sweet energy, heat in blood is the stasis of blood then, and the stasis of blood is then closed, and closes then cold and heat and does, cold and cool blood, sweet beneficial blood, heat go then blood and, and then stagnation resolvation and close logical, general rule cold and heat are from only also.Dysuria, due to interior-heat also, pyrolysis then just diarrhea.Pouring person, caused by blood system deficiency-heat also, removing heat from blood benefit blood, then drench spontaneous recovery, and the exopathogenic heat of the intestines and stomach is explained by oneself, and body fluid is raw and yearningly also stop.Blood stored in the liver and main muscle, cool liver of enriching blood, then muscle is hard.Heat in blood then collapses, and removing heat from blood and blood, then collapse spontaneous recovery.Heat in blood is absurd row then, overflow upper orifices for telling, for coughing up, be epistaxis, bleeding from the gum, removing heat from blood and blood, then all cards are from removing.Strengthening the spleen invigorating middle warmer, diuresis, therefore swollen jaundice of also harnessing the river, and hold concurrently reason typhoid fever hiccup also.
Pericarpium Citri Reticulatae: be the dry mature skin of rutaceae orange Citrus reticulata Blanco and variety thereof.Nature and flavor: temperature are pungent, bitter.Enter spleen, stomach, lung meridian.Effect: regulating qi-flowing for strengthening spleen, in tune, dampness, reduces phlegm.This product temperature can circulation of qi promoting, pungently can disperse, bitter and sluice.Pericarpium Citri Reticulatae and the same use of Fructus Aurantii Immaturus, acrid in the mouth circulation of qi promoting, fragrance enters spleen, therefore can promoting the circulation of QI to relieve pain, spleen invigorating and in, Pericarpium Citri Reticulatae and the Rhizoma Pinelliae can drying dampness to eliminate phlegm with use, again can warming for resolving cold-phlegm.
The Radix Paeoniae Alba: be the dry root of dicotyledon ranunculaceae plant Radix Paeoniae Paeonia lactiflora Pall..Nature and flavor: cool, picric acid, is slightly cold.Effect: easing the affected liver of enriching blood, suppressing the hyperactive liver pain relieving, yin fluid astringing receives antiperspirant.Research shows: the paeoniflorin contained in the Radix Paeoniae Alba has antibacterial, antipyretic, antiinflammatory, increase coronary flow, improves the effect of myocardial nutritional flow, blood vessel dilating, antagonism acute myocardial ischemia, anticoagulant, calmness, analgesia, spasmolytic, antiulcer, adjustment blood glucose.Radix Paeoniae Alba decoct can suppress dysentery bacterium, streptococcus pneumoniae, escherichia coli, Bacillus typhi, Hemolytic streptococcus, bacillus pyocyaneus etc.This product energy nourishing the liver blood, holding back liver-yin, subduing the hyperfunction of the liver sun, dispersing liver-energy, can delay again that contraction is anxious, relieve the pain pain, is the good medicine of the various pain for the treatment of Liver Channel.
Radix Scrophulariae: be the dry root of goatweed Radix Scrophulariae Scrophularia ningpoensis Hemsl..Nature and flavor: sweet, bitter, salty, are slightly cold.Return lung, stomach, kidney channel.Effect: clearing away heat and cooling blood, eliminating fire and detoxication, YIN nourishing.There is slight hypoglycemic activity.To join the army for: warm febrile disease the card of blood, consumption of YIN caused by febrile disease.There is clearing away heat and cooling blood, effect of removing toxic substances YIN nourishing.Control warm febrile disease to join the army blood, impairment of YIN robs the fever of the body excessive thirst caused by liquid, uneasy sleeping at night, crimson tongue person, can share, as qingying decoction with the medicine such as the Radix Rehmanniae, Cornu rhinocerotis, Radix Salviae Miltiorrhizae; Control the high fever that warm febrile disease falls into pericardium, unconsciousness and delirium person, can share, as clearing heat in the pericardium soup with medicines such as Cornu rhinocerotis, golden bell core, Radix Ophiopogonis; Control epidemic febrile disease Gao Refa speckle person, can share, as Huaban Tang with medicines such as Gypsum Fibrosum, Cornu rhinocerotis, the Rhizoma Anemarrhenaes.
Radix Notoginseng: be the dry root of panax araliaceae plant Panax notoginseng (Burk.) F. H. Chen.Nature and flavor: sweet, micro-hardship, temperature.Return liver, stomach warp.Effect: dissipating blood stasis stops blooding, subduing swelling and relieving pain.For spitting of blood, spit blood, epistaxis, has blood in stool, metrorrhagia, traumatic hemorrhage, and breast abdomen twinges, tumbling and swelling.Record in " book on Chinese herbal medicine is looked for the truth ": Radix Notoginseng, common people only know that function is stopped blooding bitterly, hardly realize bitterly because blood stasis then aches work, and blood is because only applying loose then blood.The bitter temperature of Radix Notoginseng abnormal smells from the patient, can in its blood stasis of blood systemization.
Semen Euryales: be the dry mature kernal of nymphaeaceae plant Gorgon euryale Euryale ferox Salisb..Nature and flavor: sweet, puckery are flat.Return spleen, kidney channel.Effect: supplementing the kidney to control the nocturnal, spleen reinforcing antidiarrheal, damp eliminating leukorrhagia stopping.For emission, enuresis frequent micturition, insufficiency of the spleen chronic diarrhea, nebulousurine, leukorrhagia.Record in " Bencao Congxin ": " spleen reinforcing is reinforced the kidney, and helps gas arresting seminal emission.Control emission, separate summer-heat alcoholism, treat foul leukorrhea and have loose bowels, incontinence of urine." " book on Chinese herbal medicine is newly organized ": Semen Euryales, assistant envoy also, entirely dry in the kidney invigorating by its merit.The medicine of husband's the kidney invigorating, moist person is in the majority mostly, and moist person is then rather few wet.Semen Euryales invigorating middle warmer is dried, and property is not dry again, therefore the water and mend true water, use same with all YIN-tonifying drug of uncharming, especially can help to add essence, do not consider and throw humidification more yet.The not special benefit essence of Semen Euryales, and can arresting seminal emission the kidney invigorating.With Rhizoma Dioscoreae and use, be respectively end, everyday rice is taken after mixing with liquid.
The Radix Stemonae: be the dried root of Stemonaceae plant Radix Stemonae Stemona sessilifolia (Miq.) Miq., Radix stemonae japonicae Stemona japonica (Bl.) Miq. or radix stemonae tuberosae Stemona tuberosa Lour..Nature and flavor: sweet, bitter, tepor.Return lung meridian.Slightly poisonous.Effect: nourishing the lung to keep the adverse QI downward cough-relieving, parasite killing.Cough for new chronic cough, pulmonary tuberculosis cough, pertussis; Outer for head louse, body louse, enterobiasis, pudendal pruritus.For deficiency of YIN chronic cough.Research shows that Radix stemonae japonicae infusion is in vitro to various pathogens, and some pathomycete has certain inhibitory action.
Radix Asteris: be the dry root and rhizome of feverfew Radix Asteris Aster tataricus L. f..Nature and flavor: pungent, bitter, temperature.Return lung meridian.Effect: nourishing the lung to keep the adverse QI downward, stopping coughing and removing phlegm.Breath with cough for abundant expectoration, new chronic cough is coughed, chronic cough hemoptysis.The traditional Chinese medical science thinks that Radix Asteris has warming the lung, the therapeutic method to keep the adverse QI flowing downwards, the function that expectorant, cough-relieving are coughed.Radix Asteris has certain inhibitory action to 7 kinds of Gram-negative enteral pathogenic bacterium such as escherichia coli, dysentery bacterium, mycetozoan, Bacillus typhi, Salmonella paratyphi, bacillus pyocyaneus and vibrio cholera in vitro; And have the effect of antagonism pathogenic fungus.Water decoction infected by influenza in chick embryo allantois has obvious inhibitory action.There is significantly antibacterial and antiviral effect.This product master enters lung meridian, and bitter in the mouth falls to be let out, slightly warm in nature and matter profit, has again the property of unclogging and readjusting and opening concurrently, can fall lung qi, again can lung qi dispersing gas and reach the merit of relieving cough and asthma, is the key medicine for the treatment of cough with asthma.
Radix Glehniae: be the dry root of samphire glehnia littoralis Glehnia littoralis Fr. Schmidt ex Miq..Nature and flavor: sweet, micro-hardship, to be slightly cold.Return lung, kidney channel.Effect: nourishing YIN and clearing away lung-heat, reinforcing stomach reg fluid.Thirsty for lung-heat type cough, chronic cough expectorant blood, calentura Tianjin wound.Research display: Radix Glehniae not only has the effect of antipyretic-antalgic, can also strengthen body immunity.
Rhizoma Zingiberis Recens: be the fresh rhizome of zingiber Zingiber officinale Rosc..Nature and flavor are pungent, tepor.Return lung, spleen, stomach warp.Effect: relieving the exterior syndrome by diaphoresis, warming middle-JIAO to arrest vomiting, warming the lung to relieve cough, solving toxin of fish and crab, separates poison of drug.Especially for fish Eriocheir sinensis poison, the drug intoxication such as the Rhizoma Pinelliae, Rhizoma Arisaematis has Detoxication.
Radix Glycyrrhizae: be the dry root and rhizome of glycyrrhizic legume Glycyrrhiza uralensis Fisch., Glycyrrhiza inflata Bat. Glycyrrhiza Inflata Bat. or Glycyrrhiza glabra L. Glycyrrhiza Glabra L..Nature and flavor: sweet are flat.GUIXIN, lung, spleen, stomach warp.Effect: spleen reinforcing stomach function regulating, Yiqi and vein recovery." Japan hanako materia medica ": peace soul determines soul.Mend five kinds of strain and seven kinds of impairment, all be deficient, palpitation with fear, unhappy, forgetful.Logical nine orifices, sharp hundred arteries and veins, beneficial intensive culture gas, strengthening bone and muscle, separates cold and hot.
Fructus Jujubae: be the dry mature fruit of Rhamnaceae jujube Fructus Jujubae Ziziphus jujuba Mill. var. inermis (Bunge) Rehd..Nature and flavor: sweet, temperature.Return spleen, stomach warp.Effect: really (Fructus Jujubae): invigorating the spleen and replenishing QI, nourishing blood to tranquillize the mind.For insufficiency of the spleen lack of appetite, weak loose stool, woman hysteria." herbal classic ": main trusted subordinate's pathogen, regulating the spleen and stomach supports spleen, helps 12 warps.Flat gastric qi, logical nine orifices, mends weak breath, few body fluid, not enough, frightened in body, heaviness of limbs, and hundred medicines." book on Chinese herbal medicine is new again ": invigorating the spleen and replenishing QI, nourishing kidney warming the stomach, controls the deficiency of YIN.
Side's solution of the present invention is: side in Carapax et Plastrum Testudinis nourishing YIN for suppressing the hyperactive YANG, kidney tonifying bone strengthening, nourish heart and enrich blood, Colla Corii Asini nourishing blood YIN nourishing, moisturize hemostasis, Cordyceps invigorating the lung and the kidney, hemostasis and phlegm, Bulbus Lilii nourishing YIN and moistening the lung, clearing away heart-fire for tranquillization, Radix Rehmanniae clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting, the above five tastes are monarch drug altogether, fundamentally carry out conditioning health from health, pacify the five internal organs, the traditional Chinese medical science is said the five internal organs are all identical, by conditioning health, make patient can health invigorating, thus fundamentally prevent and treat generation lungy.Bulbus Fritillariae Cirrhosae clearing heat and moistening lung, preventing phlegm from forming and stopping coughing, Radix Curcumae regulating qi to disperse stagnation, heart fire-clearing upset-relieving, Vascular aurantii activating QI to eliminate phlegm, Retinervus Luffae Fructus dredging collateral is invigorated blood circulation, Radix Bupleuri reducing fever by reconciliation, dispersing the stagnated live-QI to relieve the stagnation of QI, Stamen Nelumbinis reinforcing the kindey to control nocturnal emission, Rhizoma Imperatae cooling blood for hemostasis, clearing away heat and promoting diuresis, above seven tastes are ministerial drug altogether, increase the nourishing YIN and moistening the lung of monarch drug, effect of clearing away heat and cooling blood, also there is effect of regulating qi to disperse stagnation, activating QI to eliminate phlegm simultaneously, thus the misery that can alleviate on patient clinical and prevent tuberculosis from continuing to involve other histoorgans.Pericarpium Citri Reticulatae regulating qi-flowing for strengthening spleen, the Radix Paeoniae Alba is enriched blood easing the affected liver, suppressing the hyperactive liver pain relieving, Radix Scrophulariae clearing away heat and cooling blood, eliminating fire and detoxication, Radix Notoginseng dissipating blood stasis stops blooding, Semen Euryales supplementing the kidney to control the nocturnal, spleen reinforcing antidiarrheal, the Radix Stemonae, Radix Asteris nourishing the lung to keep the adverse QI downward, stopping coughing and removing phlegm, Radix Glehniae nourishing YIN and clearing away lung-heat, Rhizoma Zingiberis Recens relieving the exterior syndrome by diaphoresis, warming the lung to relieve cough, Fructus Jujubae is enriched blood in benefit, nourishing blood to tranquillize the mind, and above a few taste is adjuvant drug altogether, not only there is the effect increasing drug effect, also there is the effects such as dissipating blood stasis hemostasis, nourishing blood to tranquillize the mind, reduce the phenomenons such as patient's spitting of blood from the symptom of disease, thus reach the object for the treatment of.Radix Glycyrrhizae priming is returned through, coordinating the actions of various ingredients in a prescription, for making medicine.The all medicines of this side share, and the monarch and his subjects pull together, and assistant makes auxiliary altogether, has nourishing YIN for suppressing the hyperactive YANG, invigorating function of kidney and strengthening bone, nourishing YIN and moistening the lung, effect of clearing away heat and cooling blood, effectively can prevent and treat tuberculosis.
Medicine material consumption of the present invention is groped to sum up to draw through inventor in a large number, each raw material dosage is for all to have good curative effect in following weight parts scope: Carapax et Plastrum Testudinis 13-23 part, Colla Corii Asini 3-9 part, Cordyceps 2-8 part, Bulbus Lilii 7-17 part, Radix Rehmanniae 10-20 part, Bulbus Fritillariae Cirrhosae 2-8 part, Radix Curcumae 7-17 part, Vascular aurantii 7-17 part, Retinervus Luffae Fructus 10-20 part, Radix Bupleuri 7-17 part, Stamen Nelumbinis 7-17 part, Rhizoma Imperatae 10-20 part, Pericarpium Citri Reticulatae 7-17 part, Radix Paeoniae Alba 7-17 part, Radix Scrophulariae 7-17 part, Radix Notoginseng 3-9 part, Semen Euryales 4-14 part, Radix Stemonae 5-15 part, Radix Asteris 7-17 part, Radix Glehniae 10-20 part, Rhizoma Zingiberis Recens 3-9 part, Radix Glycyrrhizae 1-5 part, Fructus Jujubae 3-9 part.
Wherein be preferably: Carapax et Plastrum Testudinis 18 parts, 6 parts, Colla Corii Asini, Cordyceps 5 parts, Bulbus Lilii 12 parts, Radix Rehmanniae 15 parts, Bulbus Fritillariae Cirrhosae 5 parts, Radix Curcumae 12 parts, Vascular aurantii 12 parts, Retinervus Luffae Fructus 15 parts, Radix Bupleuri 12 parts, Stamen Nelumbinis 12 parts, Rhizoma Imperatae 15 parts, Pericarpium Citri Reticulatae 12 parts, the Radix Paeoniae Alba 12 parts, Radix Scrophulariae 12 parts, Radix Notoginseng 6 parts, Semen Euryales 9 parts, the Radix Stemonae 10 parts, Radix Asteris 12 parts, Radix Glehniae 15 parts, 6 parts, Rhizoma Zingiberis Recens, Radix Glycyrrhizae 3 parts, 6 parts, Fructus Jujubae.
Medicine of the present invention can adopt the conventional method of Chinese medicine composition to be prepared into any conventional oral preparations, as pill, powder, tablet, oral liquid etc.Such as these crude drug pulverize mix homogeneously can be made powder to take after mixing it with water; Can decocting be used, obtain filtrate after filtration, add antiseptic and make oral liquid; Also directly decoction can be taken if desired.
The preferred preparation method of the present invention is pill, and its preparation method is as follows:
Step one: according to weight proportion of the present invention, becomes medicated bag by Semen Euryales, Fructus Jujubae bundle, is put in water and soaks about 45 minutes, filters, for subsequent use;
Step 2: by weight proportion of the present invention, take Carapax et Plastrum Testudinis suitably to pulverize, put into after marmite adds step one immersion and remain cold water, exceed powder 4 ~ 8 centimetres, after being fried boiling with high heat, again with 20 ~ 30 minutes at a simmer, filter, obtain filtrate, the water of 4 cm is added in residue medicinal residues, then Radix Rehmanniae is added, Radix Curcumae, Rhizoma Imperatae, the Radix Paeoniae Alba, Radix Scrophulariae, Radix Notoginseng, the Radix Stemonae, Radix Asteris, Radix Glehniae, Rhizoma Zingiberis Recens is put into after marmite adds step one immersion and is remained cold water, exceed powder 3 ~ 4 li centimetres, after being fried boiling with high heat, again with 20 ~ 30 minutes at a simmer, filter, obtain filtrate, the water of 3 cm is added in residue medicinal residues, add Cordyceps, Bulbus Lilii, Bulbus Fritillariae Cirrhosae, Vascular aurantii, Retinervus Luffae Fructus, Radix Bupleuri, Pericarpium Citri Reticulatae, medicated bag in Radix Glycyrrhizae and step one, decoct 30 minutes, filter, waste, for subsequent use,
Step 3: twice filtrate in step 3 is merged, add Stamen Nelumbinis powder while hot, stir, and Colla Corii Asini is put in molten in gained hot soup medicine, and by about concentration of liquid medicine to 80 DEG C time, add 75% ethanol, place precipitation, filter, abandon precipitation, filtrate recycling ethanol, the thick paste of relative density 1.13 ~ 1.20 under 60 DEG C of environment, by air-dry for thick paste pulverizing, add Mel, antiseptic, wetting agent etc., carry out beating, rubbing, one-tenth ball, dry, be distributed into bag, both the honeyed pill for the treatment of interstitial lung disease of the present invention.
Medicine of the present invention has nourishing YIN for suppressing the hyperactive YANG, invigorating function of kidney and strengthening bone, nourishing YIN and moistening the lung, the effects such as clearing away heat and cooling blood, and control takes into account, determined curative effect, easy to use, have no side effect, the mode that this Chinese medicine composition adopts is treated and can be reduced the damage of Western medicine to human liver renal function, alleviates the slight illness of patient.According to clinical 240 routine patient view statistics, use medicine of the present invention the total effective rate course for the treatment of 90%, two the total effective rate course for the treatment of 96.7%.
Detailed description of the invention
Embodiment one, Carapax et Plastrum Testudinis 13 parts, 3 parts, Colla Corii Asini, Cordyceps 2 parts, Bulbus Lilii 7 parts, Radix Rehmanniae 10 parts, Bulbus Fritillariae Cirrhosae 2 parts, Radix Curcumae 7 parts, Vascular aurantii 7 parts, Retinervus Luffae Fructus 10 parts, Radix Bupleuri 7 parts, Stamen Nelumbinis 7 parts, Rhizoma Imperatae 10 parts, Pericarpium Citri Reticulatae 7 parts, the Radix Paeoniae Alba 7 parts, Radix Scrophulariae 7 parts, Radix Notoginseng 3 parts, Semen Euryales 4 parts, the Radix Stemonae 5 parts, Radix Asteris 7 parts, Radix Glehniae 10 parts, 3 parts, Rhizoma Zingiberis Recens, Radix Glycyrrhizae 1 part, 3 parts, Fructus Jujubae.
Embodiment two, Carapax et Plastrum Testudinis 18 parts, 6 parts, Colla Corii Asini, Cordyceps 5 parts, Bulbus Lilii 12 parts, Radix Rehmanniae 15 parts, Bulbus Fritillariae Cirrhosae 5 parts, Radix Curcumae 12 parts, Vascular aurantii 12 parts, Retinervus Luffae Fructus 15 parts, Radix Bupleuri 12 parts, Stamen Nelumbinis 12 parts, Rhizoma Imperatae 15 parts, Pericarpium Citri Reticulatae 12 parts, the Radix Paeoniae Alba 12 parts, Radix Scrophulariae 12 parts, Radix Notoginseng 6 parts, Semen Euryales 9 parts, the Radix Stemonae 10 parts, Radix Asteris 12 parts, Radix Glehniae 15 parts, 6 parts, Rhizoma Zingiberis Recens, Radix Glycyrrhizae 3 parts, 6 parts, Fructus Jujubae.
Embodiment three, Carapax et Plastrum Testudinis 23 parts, 9 parts, Colla Corii Asini, Cordyceps 8 parts, Bulbus Lilii 17 parts, Radix Rehmanniae 20 parts, Bulbus Fritillariae Cirrhosae 8 parts, Radix Curcumae 17 parts, Vascular aurantii 17 parts, Retinervus Luffae Fructus 20 parts, Radix Bupleuri 17 parts, Stamen Nelumbinis 17 parts, Rhizoma Imperatae 20 parts, Pericarpium Citri Reticulatae 17 parts, the Radix Paeoniae Alba 17 parts, Radix Scrophulariae 17 parts, Radix Notoginseng 9 parts, Semen Euryales 14 parts, the Radix Stemonae 15 parts, Radix Asteris 17 parts, Radix Glehniae 20 parts, 9 parts, Rhizoma Zingiberis Recens, Radix Glycyrrhizae 5 parts, 9 parts, Fructus Jujubae.
Here is the clinical statistics data that patient uses medicine of the present invention:
One, physical data and Therapeutic Method
Accept out-patient 240 example for medical treatment.According to Medications Example two of the present invention, and honeyed pill prepared by preferred preparation method, sooner or later service once, each 2, decoction being taken warmly.It within 10th, is a course for the treatment of.
Two, efficacy assessment standard
1, cure: clinical symptoms lungy disappears completely, and the tuberculosis symptom manifested everywhere disappears all completely, place's enlargements such as bone, joint, lymph disappear, and routine urinalysis etc. check normal.
2, take a turn for the better: clinical symptoms lungy is alleviated gradually, and the tuberculosis symptom manifested everywhere is controlled.
3, do not heal: control lungy is without any effect.
Three, therapeutic outcome statistics
As can be seen from above-mentioned, Chinese medicine of the present invention has good clinical effectiveness preventing and treating in tuberculosis, effectively can improve the cure rate for the treatment of, be worth promoting in clinical practice.
Model case and curative effect:
Case one, Ma, female, 41 years old, often there is lumbago in recent months, and once in a while with fever, loss of appetite, the symptoms such as cold perspiration, remove examination in hospital, be diagnosed as tuberculosis of spine, treat two wheat harvesting periods at hospital, effect is not clearly, carrys out here treatment after being introduced, adopt case two method of the present invention, after patient takes two courses for the treatment of, sensory symptoms obviously alleviates, and diet, sleep and body constitution are strengthened all to some extent, continue two courses for the treatment of of use, patient goes to hospital to check, and lumbar vertebra place tuberculosis symptom disappears completely, recovery from illness.
Case two, Wang, man, 22 years old, patient suffers from pulmonary tuberculosis, seeks medical advice everywhere, takes various medicine and treats, but effect is not clearly always, went to a doctor in here afterwards, adopts case two method of the present invention, after patient took for two each and every one courses for the treatment of, sensory symptoms obviously alleviates, and cough, spitting of blood phenomenon fade away, body constitution is restored gradually, and continue a course for the treatment of of use, patient's readme feels light from head to foot, go to hospital to check, pulmonary tuberculosis is fully recovered.
Case three, appoint certain, female, 50 years old, patient suffers from bone tuberculosis, and focus is at lumbar vertebra position, undesirable in hospitalize effect, Post operation affected area recurs, and skin and flesh festers, and comes here and goes to a doctor, adopt case two method of the present invention, after patient takes three courses for the treatment of, sensory symptoms obviously alleviates, symptom disappears substantially, continues a course for the treatment of of use, and symptom completely disappearance affected area is recovered as before, go to hospital to check, every inspection is normal, recovery from illness.

Claims (4)

1. a control Chinese medicine composition lungy, it is characterized in that, this Chinese medicine composition is made up of the medicine of following weight portion: Carapax et Plastrum Testudinis 13-23 part, Colla Corii Asini 3-9 part, Cordyceps 2-8 part, Bulbus Lilii 7-17 part, Radix Rehmanniae 10-20 part, Bulbus Fritillariae Cirrhosae 2-8 part, Radix Curcumae 7-17 part, Vascular aurantii 7-17 part, Retinervus Luffae Fructus 10-20 part, Radix Bupleuri 7-17 part, Stamen Nelumbinis 7-17 part, Rhizoma Imperatae 10-20 part, Pericarpium Citri Reticulatae 7-17 part, Radix Paeoniae Alba 7-17 part, Radix Scrophulariae 7-17 part, Radix Notoginseng 3-9 part, Semen Euryales 4-14 part, Radix Stemonae 5-15 part, Radix Asteris 7-17 part, Radix Glehniae 10-20 part, Rhizoma Zingiberis Recens 3-9 part, Radix Glycyrrhizae 1-5 part, Fructus Jujubae 3-9 part.
2. the Chinese medicine composition lungy of the control according to claims 1, it is characterized in that, be made up of the medicine of following weight portion: Carapax et Plastrum Testudinis 18 parts, 6 parts, Colla Corii Asini, Cordyceps 5 parts, Bulbus Lilii 12 parts, Radix Rehmanniae 15 parts, Bulbus Fritillariae Cirrhosae 5 parts, Radix Curcumae 12 parts, Vascular aurantii 12 parts, Retinervus Luffae Fructus 15 parts, Radix Bupleuri 12 parts, Stamen Nelumbinis 12 parts, Rhizoma Imperatae 15 parts, Pericarpium Citri Reticulatae 12 parts, the Radix Paeoniae Alba 12 parts, Radix Scrophulariae 12 parts, Radix Notoginseng 6 parts, Semen Euryales 9 parts, the Radix Stemonae 10 parts, Radix Asteris 12 parts, Radix Glehniae 15 parts, 6 parts, Rhizoma Zingiberis Recens, Radix Glycyrrhizae 3 parts, 6 parts, Fructus Jujubae.
3. control according to claim 1 and 2 Chinese medicine composition lungy, is characterized in that: described Chinese medicine composition is pill.
4. prevent and treat a Chinese medicine composition for Chinese medicine composition lungy, it is characterized in that, preparation method is as follows: step one: according to weight proportion of the present invention, and Semen Euryales, Fructus Jujubae bundle are become medicated bag, is put in water and soaks about 45 minutes, filters, for subsequent use, step 2: by weight proportion of the present invention, take Carapax et Plastrum Testudinis suitably to pulverize, put into after marmite adds step one immersion and remain cold water, exceed powder 4 ~ 8 centimetres, after being fried boiling with high heat, again with 20 ~ 30 minutes at a simmer, filter, obtain filtrate, the water of 4 cm is added in residue medicinal residues, then Radix Rehmanniae is added, Radix Curcumae, Rhizoma Imperatae, the Radix Paeoniae Alba, Radix Scrophulariae, Radix Notoginseng, the Radix Stemonae, Radix Asteris, Radix Glehniae, Rhizoma Zingiberis Recens is put into after marmite adds step one immersion and is remained cold water, exceed powder 3 ~ 4 li centimetres, after being fried boiling with high heat, again with 20 ~ 30 minutes at a simmer, filter, obtain filtrate, the water of 3 cm is added in residue medicinal residues, add Cordyceps, Bulbus Lilii, Bulbus Fritillariae Cirrhosae, Vascular aurantii, Retinervus Luffae Fructus, Radix Bupleuri, Pericarpium Citri Reticulatae, medicated bag in Radix Glycyrrhizae and step one, decoct 30 minutes, filter, waste, for subsequent use, step 3: twice filtrate in step 3 is merged, add Stamen Nelumbinis powder while hot, stir, and Colla Corii Asini is put in molten in gained hot soup medicine, and by about concentration of liquid medicine to 80 DEG C time, add 75% ethanol, place precipitation, filter, abandon precipitation, filtrate recycling ethanol, the thick paste of relative density 1.13 ~ 1.20 under 60 DEG C of environment, by air-dry for thick paste pulverizing, add Mel, antiseptic, wetting agent etc., carry out beating, rubbing, one-tenth ball, dry, be distributed into bag, both the honeyed pill for the treatment of interstitial lung disease of the present invention.
CN201510033410.0A 2015-01-23 2015-01-23 Traditional Chinese medicine composition for preventing and controlling tuberculosis and preparation method thereof Pending CN104491830A (en)

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CN106360546A (en) * 2016-08-25 2017-02-01 明光市昊昊蜂业有限公司 Traditional Chinese medicine health caring honey and preparation method thereof

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